| Year |
Citation |
Score |
| 2024 |
Rana J, Herzog RW, Muñoz-Melero M, Yamada K, Kumar SRP, Lam AK, Markusic DM, Duan D, Terhorst C, Byrne BJ, Corti M, Biswas M. B cell focused transient immune suppression protocol for efficient AAV readministration to the liver. Molecular Therapy. Methods & Clinical Development. 32: 101216. PMID 38440160 DOI: 10.1016/j.omtm.2024.101216 |
0.302 |
|
| 2023 |
Shoti J, Qing K, Keeler GD, Duan D, Byrne BJ, Srivastava A. Development of capsid- and genome-modified optimized AAVrh74 vectors for muscle gene therapy. Molecular Therapy. Methods & Clinical Development. 31: 101147. PMID 38046199 DOI: 10.1016/j.omtm.2023.101147 |
0.419 |
|
| 2023 |
Haffner V, Nourian Z, Boerman EM, Lambert MD, Hanft LM, Krenz M, Baines CP, Duan D, McDonald KS, Domeier TL. Calcium handling dysfunction and cardiac damage following acute ventricular preload challenge in the dystrophin-deficient mouse heart. American Journal of Physiology. Heart and Circulatory Physiology. PMID 37737731 DOI: 10.1152/ajpheart.00265.2023 |
0.315 |
|
| 2023 |
Duan D. Duchenne Muscular Dystrophy Gene Therapy in 2023: Status, Perspective, and Beyond. Human Gene Therapy. 34: 345-349. PMID 37219994 DOI: 10.1089/hum.2023.29242.ddu |
0.34 |
|
| 2023 |
Kumar SRP, Duan D, Herzog R. Immune Responses to Muscle-Directed AAV Gene Transfer in Clinical Studies. Human Gene Therapy. PMID 37154743 DOI: 10.1089/hum.2023.056 |
0.398 |
|
| 2023 |
Morales ED, Yue Y, Watkins TB, Han J, Pan X, Gibson AM, Hu B, Brito-Estrada O, Yao G, Makarewich CA, Babu GJ, Duan D. Dwarf Open Reading Frame (DWORF) Gene Therapy Ameliorated Duchenne Muscular Dystrophy Cardiomyopathy in Aged mdx Mice. Journal of the American Heart Association. e027480. PMID 36695318 DOI: 10.1161/JAHA.122.027480 |
0.419 |
|
| 2023 |
Chamberlain J, Robb M, Braun S, Brown K, Danos O, Ganot A, Gonzalez-Alegre P, Hunter N, McDonald C, Morris C, Tobolowsky M, Wagner K, Ziolkowski O, Duan D. Micro-dystrophin expression as a surrogate endpoint for Duchenne muscular dystrophy clinical trials. Human Gene Therapy. PMID 36694468 DOI: 10.1089/hum.2022.190 |
0.433 |
|
| 2023 |
Birch SM, Lawlor MW, Conlon TJ, Guo LJ, Crudele JM, Hawkins EC, Nghiem PP, Ahn M, Meng H, Beatka MJ, Fickau BA, Prieto JC, Styner MA, Struharik MJ, Shanks C, ... ... Duan D, et al. Assessment of systemic AAV-microdystrophin gene therapy in the GRMD model of Duchenne muscular dystrophy. Science Translational Medicine. 15: eabo1815. PMID 36599002 DOI: 10.1126/scitranslmed.abo1815 |
0.408 |
|
| 2022 |
Wasala N, Yue Y, Hu B, Shin JH, Srivastava A, Yao G, Duan D. Life-long outcomes of systemic AAV micro-dystrophin gene therapy in a murine Duchenne muscular dystrophy model. Human Gene Therapy. PMID 36515166 DOI: 10.1089/hum.2022.181 |
0.336 |
|
| 2022 |
Hakim CH, Kumar SRP, Pérez-López D, Teixeira J, Herzog RW, Duan D. Assessment of the Gene Therapy Immune Response in the Canine Muscular Dystrophy Model. Methods in Molecular Biology (Clifton, N.J.). 2587: 353-375. PMID 36401038 DOI: 10.1007/978-1-0716-2772-3_18 |
0.322 |
|
| 2022 |
Zalcman AR, Hakim CH, Lattimer JC, Holland JR, Dodam JR, Duan D. MRI Evaluation of Gene Therapy in the Canine Model of Duchenne Muscular Dystrophy. Methods in Molecular Biology (Clifton, N.J.). 2587: 339-352. PMID 36401037 DOI: 10.1007/978-1-0716-2772-3_17 |
0.363 |
|
| 2022 |
Hakim CH, Burke MJ, Teixeira J, Duan D. Histological Assessment of Gene Therapy in the Canine DMD Model. Methods in Molecular Biology (Clifton, N.J.). 2587: 303-338. PMID 36401036 DOI: 10.1007/978-1-0716-2772-3_16 |
0.383 |
|
| 2022 |
Hakim CH, Pérez-López D, Burke MJ, Teixeira J, Duan D. Molecular and Biochemical Assessment of Gene Therapy in the Canine Model of Duchenne Muscular Dystrophy. Methods in Molecular Biology (Clifton, N.J.). 2587: 255-301. PMID 36401035 DOI: 10.1007/978-1-0716-2772-3_15 |
0.432 |
|
| 2022 |
Hakim CH, Teixeira J, Leach SB, Duan D. Physiological Assessment of Muscle, Heart, and Whole Body Function in the Canine Model of Duchenne Muscular Dystrophy. Methods in Molecular Biology (Clifton, N.J.). 2587: 67-103. PMID 36401025 DOI: 10.1007/978-1-0716-2772-3_5 |
0.36 |
|
| 2022 |
Wasala N, Million ED, Watkins T, Wasala LP, Han J, Yue Y, Lu B, Chen SJ, Hakim C, Duan D. The gRNA vector level determines the outcome of systemic AAV CRISPR therapy for Duchenne muscular dystrophy. Human Gene Therapy. PMID 35350865 DOI: 10.1089/hum.2021.130 |
0.328 |
|
| 2021 |
Hakim CH, Kumar SRP, Pérez-López DO, Wasala NB, Zhang D, Yue Y, Teixeira J, Pan X, Zhang K, Million ED, Nelson CE, Metzger S, Han J, Louderman JA, Schmidt F, ... ... Duan D, et al. Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models. Nature Communications. 12: 6769. PMID 34819506 DOI: 10.1038/s41467-021-26830-7 |
0.328 |
|
| 2021 |
Zheng A, Arias EB, Wang H, Kwak SE, Pan X, Duan D, Cartee GD. The Exercise-induced Improvement in Insulin-stimulated Glucose Uptake by Rat Skeletal Muscle Is Absent in Male AS160-Knockout Rats, Partially Restored by Muscle Expression of Phosphomutated AS160, and Fully Restored by Muscle Expression of Wildtype AS160. Diabetes. PMID 34753801 DOI: 10.2337/db21-0601 |
0.308 |
|
| 2021 |
Hakim CH, Yang HT, Burke MJ, Teixeira J, Jenkins GJ, Yang NN, Yao G, Duan D. Extensor carpi ulnaris muscle shows unexpected slow-to-fast fiber type switch in Duchenne muscular dystrophy dogs. Disease Models & Mechanisms. PMID 34704592 DOI: 10.1242/dmm.049006 |
0.351 |
|
| 2021 |
Pan X, Yue Y, Boftsi M, Wasala LP, Tran NT, Zhang K, Pintel DJ, Tai PWL, Duan D. Rational engineering of a functional CpG-free ITR for AAV gene therapy. Gene Therapy. PMID 34611321 DOI: 10.1038/s41434-021-00296-0 |
0.392 |
|
| 2021 |
Mareedu S, Million ED, Duan D, Babu GJ. Abnormal Calcium Handling in Duchenne Muscular Dystrophy: Mechanisms and Potential Therapies. Frontiers in Physiology. 12: 647010. PMID 33897454 DOI: 10.3389/fphys.2021.647010 |
0.341 |
|
| 2021 |
Duan D, Goemans N, Takeda S, Mercuri E, Aartsma-Rus A. Duchenne muscular dystrophy. Nature Reviews. Disease Primers. 7: 13. PMID 33602943 DOI: 10.1038/s41572-021-00248-3 |
0.345 |
|
| 2020 |
Zhao J, Yue Y, Patel A, Wasala L, Karp JF, Zhang K, Duan D, Lai Y. High-Resolution Histological Landscape of AAV DNA Distribution in Cellular Compartments and Tissues following Local and Systemic Injection. Molecular Therapy. Methods & Clinical Development. 18: 856-868. PMID 32953935 DOI: 10.1016/J.Omtm.2020.08.006 |
0.418 |
|
| 2020 |
Hakim CH, Clément N, Wasala LP, Yang HT, Yue Y, Zhang K, Kodippili K, Adamson-Small L, Pan X, Schneider JS, Yang NN, Chamberlain JS, Byrne BJ, Duan D. Micro-dystrophin AAV Vectors Made by Transient Transfection and Herpesvirus System Are Equally Potent in Treating mdx Mouse Muscle Disease. Molecular Therapy. Methods & Clinical Development. 18: 664-678. PMID 32775499 DOI: 10.1016/J.Omtm.2020.07.004 |
0.497 |
|
| 2020 |
Chiao YA, Zhang H, Sweetwyne M, Whitson J, Ting YS, Basisty N, Pino LK, Quarles E, Nguyen NH, Campbell MD, Zhang T, Gaffrey MJ, Merrihew G, Wang L, Yue Y, ... Duan D, et al. Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice. Elife. 9. PMID 32648542 DOI: 10.7554/Elife.55513 |
0.319 |
|
| 2020 |
White Z, Hakim CH, Theret M, Yang NN, Rossi F, Cox D, Francis GA, Straub V, Selby K, Panagiotopoulos C, Duan D, Bernatchez P. High prevalence of plasma lipid abnormalities in human and canine Duchenne and Becker muscular dystrophies depicts a new type of primary genetic dyslipidemia. Journal of Clinical Lipidology. PMID 32593511 DOI: 10.1016/J.Jacl.2020.05.098 |
0.385 |
|
| 2020 |
Nance ME, Ravanfar M, Messler M, Duan D, Yao G. Temporal dynamics of muscle optical properties during degeneration and regeneration in a canine muscle xenograft model. Biomedical Optics Express. 11: 2383-2393. PMID 32499931 DOI: 10.1364/Boe.390936 |
0.354 |
|
| 2020 |
Story BD, Miller ME, Bradbury AM, Million ED, Duan D, Taghian T, Faissler D, Fernau D, Beecy SJ, Gray-Edwards HL. Canine Models of Inherited Musculoskeletal and Neurodegenerative Diseases. Frontiers in Veterinary Science. 7: 80. PMID 32219101 DOI: 10.3389/Fvets.2020.00080 |
0.309 |
|
| 2020 |
Wasala NB, Chen SJ, Duan D. Duchenne muscular dystrophy animal models for high-throughput drug discovery and precision medicine. Expert Opinion On Drug Discovery. 1-14. PMID 32000537 DOI: 10.1080/17460441.2020.1718100 |
0.371 |
|
| 2020 |
Wasala NB, Yue Y, Lostal W, Wasala LP, Niranjan N, Hajjar RJ, Babu GJ, Duan D. Single SERCA2a Therapy Ameliorated Dilated Cardiomyopathy for 18 Months in a Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31981493 DOI: 10.1016/J.Ymthe.2019.12.011 |
0.43 |
|
| 2019 |
Hakim CH, Lessa TB, Jenkins GJ, Yang NN, Ambrosio CE, Duan D. An improved method for studying mouse diaphragm function. Scientific Reports. 9: 19453. PMID 31857625 DOI: 10.1038/S41598-019-55704-8 |
0.387 |
|
| 2019 |
Duan D. Micro-utrophin Therapy for Duchenne Muscular Dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 27: 1872-1874. PMID 31653398 DOI: 10.1016/J.Ymthe.2019.10.011 |
0.34 |
|
| 2019 |
Niranjan N, Mareedu S, Tian Y, Kodippili K, Fefelova N, Voit A, Xie LH, Duan D, Babu GJ. Sarcolipin overexpression impairs myogenic differentiation in Duchenne muscular dystrophy. American Journal of Physiology. Cell Physiology. PMID 31365291 DOI: 10.1152/Ajpcell.00146.2019 |
0.345 |
|
| 2019 |
Nance ME, Shi R, Hakim CH, Wasala NB, Yue Y, Pan X, Zhang T, Robinson CA, Duan SX, Yao G, Yang NN, Chen SJ, Wagner KR, Gersbach CA, Duan D. AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31327755 DOI: 10.1016/J.Ymthe.2019.06.012 |
0.517 |
|
| 2019 |
Zhao J, Yang HT, Wasala L, Zhang K, Yue Y, Duan D, Lai Y. Dystrophin R16/17 protein therapy restores sarcolemmal nNOS in trans and improves muscle perfusion and function. Molecular Medicine (Cambridge, Mass.). 25: 31. PMID 31266455 DOI: 10.1186/S10020-019-0101-6 |
0.471 |
|
| 2019 |
Pan X, Sands SA, Yue Y, Zhang K, LeVine SM, Duan D. An engineered galactosylceramidase construct improves AAV gene therapy for Krabbe disease in twitcher mice. Human Gene Therapy. PMID 31184217 DOI: 10.1089/Hum.2019.008 |
0.444 |
|
| 2019 |
Patel A, Zhao J, Duan D, Lai Y. Design of AAV Vectors for Delivery of Large or Multiple Transgenes. Methods in Molecular Biology (Clifton, N.J.). 1950: 19-33. PMID 30783966 DOI: 10.1007/978-1-4939-9139-6_2 |
0.495 |
|
| 2019 |
Wasala LP, Hakim CH, Yue Y, Yang NN, Duan D. Systemic Delivery of Adeno-Associated Viral Vectors in Mice and Dogs. Methods in Molecular Biology (Clifton, N.J.). 1937: 281-294. PMID 30706404 DOI: 10.1007/978-1-4939-9065-8_18 |
0.497 |
|
| 2019 |
Wasala NB, Hakim C, Chen SJ, Yang NN, Duan D. Questions answered and unanswered by the first CRISPR editing study in the canine model of Duchenne muscular dystrophy. Human Gene Therapy. PMID 30648435 DOI: 10.1089/Hum.2018.243 |
0.497 |
|
| 2018 |
Duan D. CRISPR alleviates muscular dystrophy in dogs. Nature Biomedical Engineering. 2: 795-796. PMID 31015617 DOI: 10.1038/S41551-018-0320-0 |
0.455 |
|
| 2018 |
Hakim CH, Wasala NB, Nelson CE, Wasala LP, Yue Y, Louderman JA, Lessa TB, Dai A, Zhang K, Jenkins GJ, Nance ME, Pan X, Kodippili K, Yang NN, Chen SJ, ... ... Duan D, et al. AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice. Jci Insight. 3. PMID 30518686 DOI: 10.1172/Jci.Insight.124297 |
0.562 |
|
| 2018 |
Patel A, Zhao J, Yue Y, Zhang K, Duan D, Lai Y. Dystrophin R16/17-syntrophin PDZ fusion protein restores sarcolemmal nNOSμ. Skeletal Muscle. 8: 36. PMID 30466494 DOI: 10.1186/S13395-018-0182-X |
0.432 |
|
| 2018 |
Gordish-Dressman H, Willmann R, Pazze LD, Kreibich A, van Putten M, Heydemann A, Bogdanik L, Lutz C, Davies K, Demonbruen AR, Duan D, Elsey D, Fukada SI, Girgenrath M, Gonzalez JP, et al. "Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic First Workshop Report: Examining current findings and opportunities around the emerging D2.B10-Dmdmdx/J (D2/mdx) model in context of the classic C57BL/10ScSn-Dmdmdx/J (Bl10/mdx). Journal of Neuromuscular Diseases. PMID 30198876 DOI: 10.3233/Jnd-180324 |
0.345 |
|
| 2018 |
Kodippili K, Hakim CH, Yang HT, Pan X, Yang NN, Laughlin MH, Terjung RL, Duan D. Nitric oxide dependent attenuation of norepinephrine-induced vasoconstriction is impaired in the canine model of Duchenne muscular dystrophy. The Journal of Physiology. PMID 30152022 DOI: 10.1113/Jp275672 |
0.304 |
|
| 2018 |
Duan D. Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30093306 DOI: 10.1016/J.Ymthe.2018.07.011 |
0.552 |
|
| 2018 |
Nelson DM, Lindsay A, Judge LM, Duan D, Chamberlain JS, Lowe DA, Ervasti JM. Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins. Human Molecular Genetics. PMID 29901725 DOI: 10.1093/hmg/ddy209 |
0.321 |
|
| 2018 |
Nelson DM, Lindsay A, Judge LM, Duan D, Chamberlain JS, Lowe DA, Ervasti JM. Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins. Human Molecular Genetics. PMID 29618008 DOI: 10.1093/Hmg/Ddy113 |
0.512 |
|
| 2018 |
Duan D. Micro-dystrophin gene therapy goes systemic in Duchenne muscular dystrophy patients. Human Gene Therapy. PMID 29463117 DOI: 10.1089/Hum.2018.012 |
0.51 |
|
| 2018 |
Wasala NB, Shin JH, Lai Y, Yue Y, Montanaro F, Duan D. Cardiac specific expression of ∆H2-R15 mini-dystrophin normalized all ECG abnormalities and the end-diastolic volume in a 23-m-old mouse model of Duchenne dilated cardiomyopathy. Human Gene Therapy. PMID 29433343 DOI: 10.1089/Hum.2017.144 |
0.422 |
|
| 2018 |
Wang Y, Ravanfar M, Zhang K, Duan D, Yao G. Automatic quantification of microscopic heart damage in a mouse model of Duchenne muscular dystrophy using optical polarization tractography. Journal of Biophotonics. PMID 29314725 DOI: 10.1002/Jbio.201700284 |
0.316 |
|
| 2017 |
Voit A, Patel V, Pachon R, Shah V, Bakhutma M, Kohlbrenner E, McArdle JJ, Dell'Italia LJ, Mendell JR, Xie LH, Hajjar RJ, Duan D, Fraidenraich D, Babu GJ. Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice. Nature Communications. 8: 1068. PMID 29051551 DOI: 10.1038/S41467-017-01146-7 |
0.54 |
|
| 2017 |
Hakim CH, Wasala NB, Pan X, Kodippili K, Yue Y, Zhang K, Yao G, Haffner B, Duan SX, Ramos J, Schneider JS, Yang NN, Chamberlain JS, Duan D. A Five-Repeat Micro-Dystrophin Gene Ameliorated Dystrophic Phenotype in the Severe DBA/2J-mdx Model of Duchenne Muscular Dystrophy. Molecular Therapy. Methods & Clinical Development. 6: 216-230. PMID 28932757 DOI: 10.1016/J.Omtm.2017.06.006 |
0.54 |
|
| 2017 |
Kodippili K, Hakim C, Pan X, Yang HT, YUe Y, Zhang Y, Shin JH, Yang NN, Duan D. Dual AAV gene therapy for Duchenne muscular dystrophy with a 7-kb mini-dystrophin gene in the canine model. Human Gene Therapy. PMID 28793798 DOI: 10.1089/Hum.2017.095 |
0.589 |
|
| 2017 |
Nance ME, Hakim CH, Yang NN, Duan D. Nanotherapy for Duchenne muscular dystrophy. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. PMID 28398005 DOI: 10.1002/Wnan.1472 |
0.509 |
|
| 2017 |
Hakim CH, Mijailovic A, Lessa TB, Coates JR, Shin C, Rutkove SB, Duan D. Non-invasive evaluation of muscle disease in the canine model of Duchenne muscular dystrophy by electrical impedance myography. Plos One. 12: e0173557. PMID 28339469 DOI: 10.1371/Journal.Pone.0173557 |
0.408 |
|
| 2016 |
Wasala NB, Yue Y, Vance J, Duan D. Uniform low-level dystrophin expression in the heart partially preserved cardiac function in an aged mouse model of Duchenne cardiomyopathy. Journal of Molecular and Cellular Cardiology. PMID 27908661 DOI: 10.1016/J.Yjmcc.2016.11.011 |
0.428 |
|
| 2016 |
Stroud C, Dmitriev I, Kashentseva E, Bryan JN, Curiel DT, Rindt H, Reinero C, Henry CJ, Bergman PJ, Mason NJ, Gnanandarajah JS, Engiles JB, Gray F, Laughlin D, Gaurnier-Hausser A, ... ... Duan D, et al. A One Health overview, facilitating advances in comparative medicine and translational research. Clinical and Translational Medicine. 5: 26. PMID 27558513 DOI: 10.1186/S40169-016-0107-4 |
0.311 |
|
| 2016 |
Duan D. Systemic delivery of adeno-associated viral vectors. Current Opinion in Virology. 21: 16-25. PMID 27459604 DOI: 10.1016/J.Coviro.2016.07.006 |
0.482 |
|
| 2016 |
Yue Y, Wasala NB, Bostick B, Duan D. 100-fold but not 50-fold dystrophin overexpression aggravates electrocardiographic defects in the mdx model of Duchenne muscular dystrophy. Molecular Therapy. Methods & Clinical Development. 3: 16045. PMID 27419194 DOI: 10.1038/Mtm.2016.45 |
0.481 |
|
| 2016 |
Zhao J, Kodippili K, Yue Y, Hakim CH, Wasala L, Pan X, Zhang K, Yang NN, Duan D, Lai Y. Dystrophin contains multiple independent membrane-binding domains. Human Molecular Genetics. PMID 27378693 DOI: 10.1093/Hmg/Ddw210 |
0.338 |
|
| 2016 |
Yue Y, Binalsheikh IM, Leach SB, Domeier TL, Duan D. Prospect of gene therapy for cardiomyopathy in hereditary muscular dystrophy. Expert Opinion On Orphan Drugs. 4: 169-183. PMID 27340611 DOI: 10.1517/21678707.2016.1124039 |
0.431 |
|
| 2016 |
Wasala NB, Lai Y, Shin J, Zhao J, Yue Y, Duan D. Genomic removal of a therapeutic mini-dystrophin gene from adult mice elicits a Duchenne muscular dystrophy-like phenotype. Human Molecular Genetics. PMID 27106099 DOI: 10.1093/Hmg/Ddw123 |
0.543 |
|
| 2016 |
Duan D. Dystrophin Gene Replacement and Gene Repair Therapy for Duchenne Muscular Dystrophy in 2016: An Interview. Human Gene Therapy. Clinical Development. 27: 9-18. PMID 27003751 DOI: 10.1089/Humc.2016.001 |
0.464 |
|
| 2016 |
Duan D. Dystrophin gene replacement and gene repair therapy for Duchenne muscular dystrophy in 2016. Human Gene Therapy. Clinical Development. PMID 26942265 DOI: 10.1089/Hum.2016.001 |
0.472 |
|
| 2016 |
Duan D, Rafael-Fortney JA, Blain A, Kass DA, McNally EM, Metzger JM, Spurney CF, Kinnett K. Standard Operating Procedures (SOPs) for Evaluating the Heart in Preclinical Studies of Duchenne Muscular Dystrophy. Journal of Cardiovascular Translational Research. 9: 85-6. PMID 26718928 DOI: 10.1007/S12265-015-9669-6 |
0.306 |
|
| 2016 |
Hakim C, Pan X, Kodippili K, Blessa T, Yang HT, Yao G, Leach S, Emter C, Yue Y, Zhang K, Duan SX, Wasala N, Jenkins G, Legg CR, Schneider JS, ... ... Duan D, et al. 499. Intravenous Delivery of a Novel Micro-Dystrophin Vector Prevented Muscle Deterioration in Young Adult Canine Duchenne Muscular Dystrophy Dogs Molecular Therapy. 24: S198-S199. DOI: 10.1016/S1525-0016(16)33308-1 |
0.548 |
|
| 2016 |
Nelson C, Gemberling M, Hakim CH, Ousterout DG, Thakore PI, Castellanos RM, Madhavan S, Pan X, Ran FA, Yan W, Asokan A, Zhang F, Duan D, Gersbach CA. 482. Local and Systemic Gene Editing in a Mouse Model of Duchenne Muscular Dystrophy Molecular Therapy. 24: S191. DOI: 10.1016/S1525-0016(16)33291-9 |
0.568 |
|
| 2015 |
Hakim CH, Peters AA, Feng F, Yao G, Duan D. Night Activity Reduction is a Signature Physiological Biomarker for Duchenne Muscular Dystrophy Dogs. Journal of Neuromuscular Diseases. 2: 397-407. PMID 27812508 DOI: 10.3233/Jnd-150114 |
0.372 |
|
| 2015 |
Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science (New York, N.Y.). PMID 26721684 DOI: 10.1126/Science.Aad5143 |
0.573 |
|
| 2015 |
Nance ME, Duan D. Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy. Human Gene Therapy. 26: 786-800. PMID 26414293 DOI: 10.1089/Hum.2015.107 |
0.542 |
|
| 2015 |
Yue Y, Pan X, Hakim CH, Kodippili K, Zhang K, Shin JH, Yang HT, McDonald T, Duan D. Safe and bodywide muscle transduction in young adult Duchenne muscular dystrophy dogs with adeno-associated virus. Human Molecular Genetics. 24: 5880-90. PMID 26264580 DOI: 10.1093/Hmg/Ddv310 |
0.576 |
|
| 2015 |
McNally EM, Kaltman JR, Benson DW, Canter CE, Cripe LH, Duan D, Finder JD, Hoffman EP, Judge DP, Kertesz N, Kinnett K, Kirsch R, Metzger JM, Pearson GD, Rafael-Fortney JA, et al. Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy. Circulation. 131: 1590-8. PMID 25940966 DOI: 10.1161/Circulationaha.114.015151 |
0.354 |
|
| 2015 |
Wang Y, Zhang K, Wasala NB, Duan D, Yao G. Optical polarization tractography revealed significant fiber disarray in skeletal muscles of a mouse model for Duchenne muscular dystrophy. Biomedical Optics Express. 6: 347-52. PMID 25780728 DOI: 10.1364/Boe.6.000347 |
0.425 |
|
| 2015 |
Pan X, Yue Y, Zhang K, Hakim CH, Kodippili K, McDonald T, Duan D. AAV-8 is more efficient than AAV-9 in transducing neonatal dog heart. Human Gene Therapy Methods. 26: 54-61. PMID 25763686 DOI: 10.1089/Hgtb.2014.128 |
0.527 |
|
| 2015 |
McGreevy JW, Hakim CH, McIntosh MA, Duan D. Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy. Disease Models & Mechanisms. 8: 195-213. PMID 25740330 DOI: 10.1242/Dmm.018424 |
0.466 |
|
| 2015 |
Duan D, Hakim CH, Ambrosio CE, Smith BF, Sweeney HL. Early loss of ambulation is not a representative clinical feature in Duchenne muscular dystrophy dogs: remarks on the article of Barthélémy et al. Disease Models & Mechanisms. 8: 193-4. PMID 25740329 DOI: 10.1242/Dmm.019216 |
0.416 |
|
| 2015 |
Wasala NB, Zhang K, Wasala LP, Hakim CH, Duan D. The FVB Background Does Not Dramatically Alter the Dystrophic Phenotype of Mdx Mice. Plos Currents. 7. PMID 25737807 DOI: 10.1371/Currents.Md.28266819Ca0Ec5Fefcac767Ea9A3461C |
0.398 |
|
| 2015 |
Duan D. Duchenne muscular dystrophy gene therapy in the canine model. Human Gene Therapy. Clinical Development. 26: 57-69. PMID 25710459 DOI: 10.1089/Humc.2015.006 |
0.502 |
|
| 2015 |
Cheever TR, Berkley D, Braun S, Brown RH, Byrne BJ, Chamberlain JS, Cwik V, Duan D, Federoff HJ, High KA, Kaspar BK, Klinger KW, Larkindale J, Lincecum J, Mavilio F, et al. Perspectives on best practices for gene therapy programs. Human Gene Therapy. 26: 127-33. PMID 25654329 DOI: 10.1089/Hum.2014.147 |
0.39 |
|
| 2015 |
Duan D. Duchenne muscular dystrophy gene therapy in the canine model. Human Gene Therapy. Clinical Development. PMID 25587874 DOI: 10.1089/hum.2015.006 |
0.412 |
|
| 2015 |
Kodippili K, Pan X, Yang H, Hakim C, Zhang Y, Yue Y, Duan D. 679. Efficient Reconstitution of a 7kb Therapeutic Mini-Dystrophin Gene in Duchenne Muscular Dystrophy Dog Muscle Molecular Therapy. 23: S270. DOI: 10.1016/S1525-0016(16)34288-5 |
0.608 |
|
| 2015 |
Lessa TB, Hakim CH, Ambrósio CE, Duan D. 406. The MDX/UTR +/- Mouse Is a Superior Mouse Model for Duchenne Muscular Dystrophy Molecular Therapy. 23: S160-S161. DOI: 10.1016/S1525-0016(16)34015-1 |
0.493 |
|
| 2015 |
Hakim CH, Yue Y, Lai Y, Duan D. 403. Engineering Micro-Dystrophin AAV Vector for Clinical Translation Molecular Therapy. 23: S159-S160. DOI: 10.1016/S1525-0016(16)34012-6 |
0.522 |
|
| 2014 |
Hakim CH, Yue Y, Shin JH, Williams RR, Zhang K, Smith BF, Duan D. Systemic gene transfer reveals distinctive muscle transduction profile of tyrosine mutant AAV-1, -6, and -9 in neonatal dogs. Molecular Therapy. Methods & Clinical Development. 1: 14002. PMID 25105153 DOI: 10.1038/Mtm.2014.2 |
0.576 |
|
| 2014 |
Lostal W, Kodippili K, Yue Y, Duan D. Full-length dystrophin reconstitution with adeno-associated viral vectors. Human Gene Therapy. 25: 552-62. PMID 24580018 DOI: 10.1089/Hum.2013.210 |
0.565 |
|
| 2014 |
Kodippili K, Vince L, Shin JH, Yue Y, Morris GE, McIntosh MA, Duan D. Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot. Plos One. 9: e88280. PMID 24516626 DOI: 10.1371/Journal.Pone.0088280 |
0.35 |
|
| 2014 |
Lai Y, Zhao J, Yue Y, Wasala NB, Duan D. Partial restoration of cardiac function with ΔPDZ nNOS in aged mdx model of Duchenne cardiomyopathy. Human Molecular Genetics. 23: 3189-99. PMID 24463882 DOI: 10.1093/Hmg/Ddu029 |
0.489 |
|
| 2013 |
Hakim CH, Burkin DJ, Duan D. Alpha 7 integrin preserves the function of the extensor digitorum longus muscle in dystrophin-null mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 115: 1388-92. PMID 23990247 DOI: 10.1152/Japplphysiol.00602.2013 |
0.452 |
|
| 2013 |
Li D, Duan D. Mitochondria-targeted antiaging gene therapy with adeno-associated viral vectors. Methods in Molecular Biology (Clifton, N.J.). 1048: 161-80. PMID 23929105 DOI: 10.1007/978-1-62703-556-9_13 |
0.542 |
|
| 2013 |
Zhang Y, Yue Y, Li L, Hakim CH, Zhang K, Thomas GD, Duan D. Dual AAV therapy ameliorates exercise-induced muscle injury and functional ischemia in murine models of Duchenne muscular dystrophy. Human Molecular Genetics. 22: 3720-9. PMID 23681067 DOI: 10.1093/Hmg/Ddt224 |
0.543 |
|
| 2013 |
Pan X, Yue Y, Zhang K, Lostal W, Shin JH, Duan D. Long-term robust myocardial transduction of the dog heart from a peripheral vein by adeno-associated virus serotype-8. Human Gene Therapy. 24: 584-94. PMID 23551085 DOI: 10.1089/Hum.2013.044 |
0.479 |
|
| 2013 |
Shin JH, Greer B, Hakim CH, Zhou Z, Chung YC, Duan Y, He Z, Duan D. Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring. Plos One. 8: e59875. PMID 23544107 DOI: 10.1371/Journal.Pone.0059875 |
0.301 |
|
| 2013 |
Wasala NB, Bostick B, Yue Y, Duan D. Exclusive skeletal muscle correction does not modulate dystrophic heart disease in the aged mdx model of Duchenne cardiomyopathy. Human Molecular Genetics. 22: 2634-41. PMID 23459935 DOI: 10.1093/Hmg/Ddt112 |
0.498 |
|
| 2013 |
Hakim CH, Wasala NB, Duan D. Evaluation of muscle function of the extensor digitorum longus muscle ex vivo and tibialis anterior muscle in situ in mice. Journal of Visualized Experiments : Jove. PMID 23426237 DOI: 10.3791/50183 |
0.452 |
|
| 2013 |
Shin JH, Pan X, Hakim CH, Yang HT, Yue Y, Zhang K, Terjung RL, Duan D. Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 750-7. PMID 23319056 DOI: 10.1038/Mt.2012.283 |
0.546 |
|
| 2013 |
Hakim CH, Duan D. Truncated dystrophins reduce muscle stiffness in the extensor digitorum longus muscle of mdx mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 114: 482-9. PMID 23221959 DOI: 10.1152/Japplphysiol.00866.2012 |
0.54 |
|
| 2012 |
Hakim CH, Duan D. A marginal level of dystrophin partially ameliorates hindlimb muscle passive mechanical properties in dystrophin-null mice. Muscle & Nerve. 46: 948-50. PMID 23225385 DOI: 10.1002/Mus.23536 |
0.469 |
|
| 2012 |
Yang HT, Shin JH, Hakim CH, Pan X, Terjung RL, Duan D. Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy. Plos One. 7: e44438. PMID 22973449 DOI: 10.1371/Journal.Pone.0044438 |
0.45 |
|
| 2012 |
Bostick B, Shin JH, Yue Y, Wasala NB, Lai Y, Duan D. AAV micro-dystrophin gene therapy alleviates stress-induced cardiac death but not myocardial fibrosis in >21-m-old mdx mice, an end-stage model of Duchenne muscular dystrophy cardiomyopathy. Journal of Molecular and Cellular Cardiology. 53: 217-22. PMID 22587991 DOI: 10.1016/J.Yjmcc.2012.05.002 |
0.477 |
|
| 2012 |
Lai Y, Duan D. Progress in gene therapy of dystrophic heart disease. Gene Therapy. 19: 678-85. PMID 22318092 DOI: 10.1038/Gt.2012.10 |
0.482 |
|
| 2012 |
Hakim CH, Duan D. Gender differences in contractile and passive properties of mdx extensor digitorum longus muscle. Muscle & Nerve. 45: 250-6. PMID 22246882 DOI: 10.1002/Mus.22275 |
0.485 |
|
| 2012 |
Shin JH, Yue Y, Duan D. Recombinant adeno-associated viral vector production and purification. Methods in Molecular Biology (Clifton, N.J.). 798: 267-84. PMID 22130842 DOI: 10.1007/978-1-61779-343-1_15 |
0.576 |
|
| 2012 |
Bacman SR, Williams SL, Duan D, Moraes CT. Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria-targeted restriction endonuclease. Gene Therapy. 19: 1101-6. PMID 22130448 DOI: 10.1038/Gt.2011.196 |
0.413 |
|
| 2012 |
Shin JH, Yue Y, Smith B, Duan D. Humoral immunity to AAV-6, 8, and 9 in normal and dystrophic dogs. Human Gene Therapy. 23: 287-94. PMID 22040468 DOI: 10.1089/Hum.2011.125 |
0.377 |
|
| 2012 |
Shin JH, Yue Y, Srivastava A, Smith B, Lai Y, Duan D. A simplified immune suppression scheme leads to persistent micro-dystrophin expression in Duchenne muscular dystrophy dogs. Human Gene Therapy. 23: 202-9. PMID 21967249 DOI: 10.1089/Hum.2011.147 |
0.423 |
|
| 2012 |
Zhang Y, Duan D. Novel mini-dystrophin gene dual adeno-associated virus vectors restore neuronal nitric oxide synthase expression at the sarcolemma. Human Gene Therapy. 23: 98-103. PMID 21933029 DOI: 10.1089/Hum.2011.131 |
0.519 |
|
| 2012 |
Hakim CH, Grange RW, Duan D. Reply to Head Journal of Applied Physiology. 112: 332-332. DOI: 10.1152/Japplphysiol.01425.2011 |
0.446 |
|
| 2011 |
Duan D. Gene delivery to the heart: an updated review on vectors and methods. The Journal of Gene Medicine. 13: 556. PMID 22025443 DOI: 10.1002/Jgm.1619 |
0.438 |
|
| 2011 |
Wasala NB, Shin JH, Duan D. The evolution of heart gene delivery vectors. The Journal of Gene Medicine. 13: 557-65. PMID 21837689 DOI: 10.1002/Jgm.1600 |
0.477 |
|
| 2011 |
Shin JH, Bostick B, Yue Y, Hajjar R, Duan D. SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice. Journal of Translational Medicine. 9: 132. PMID 21834967 DOI: 10.1186/1479-5876-9-132 |
0.408 |
|
| 2011 |
Bostick B, Shin JH, Yue Y, Duan D. AAV-microdystrophin therapy improves cardiac performance in aged female mdx mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1826-32. PMID 21811246 DOI: 10.1038/Mt.2011.154 |
0.496 |
|
| 2011 |
Li D, Shin JH, Duan D. iNOS ablation does not improve specific force of the extensor digitorum longus muscle in dystrophin-deficient mdx4cv mice. Plos One. 6: e21618. PMID 21738735 DOI: 10.1371/Journal.Pone.0021618 |
0.443 |
|
| 2011 |
Duan D. Duchenne muscular dystrophy gene therapy: Lost in translation? Research and Reports in Biology. 2011: 31-42. PMID 21691429 DOI: 10.2147/RRB.S13463 |
0.394 |
|
| 2011 |
Fine DM, Shin JH, Yue Y, Volkmann D, Leach SB, Smith BF, McIntosh M, Duan D. Age-matched comparison reveals early electrocardiography and echocardiography changes in dystrophin-deficient dogs. Neuromuscular Disorders : Nmd. 21: 453-61. PMID 21570848 DOI: 10.1016/J.Nmd.2011.03.010 |
0.332 |
|
| 2011 |
Hakim CH, Grange RW, Duan D. The passive mechanical properties of the extensor digitorum longus muscle are compromised in 2- to 20-mo-old mdx mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 110: 1656-63. PMID 21415170 DOI: 10.1152/Japplphysiol.01425.2010 |
0.469 |
|
| 2011 |
Shin JH, Hakim CH, Zhang K, Duan D. Genotyping mdx, mdx3cv, and mdx4cv mice by primer competition polymerase chain reaction. Muscle & Nerve. 43: 283-6. PMID 21254096 DOI: 10.1002/Mus.21873 |
0.31 |
|
| 2011 |
Yue Y, Shin JH, Duan D. Whole body skeletal muscle transduction in neonatal dogs with AAV-9. Methods in Molecular Biology (Clifton, N.J.). 709: 313-29. PMID 21194038 DOI: 10.1007/978-1-61737-982-6_21 |
0.554 |
|
| 2011 |
Bostick B, Yue Y, Duan D. Phenotyping cardiac gene therapy in mice. Methods in Molecular Biology (Clifton, N.J.). 709: 91-104. PMID 21194023 DOI: 10.1007/978-1-61737-982-6_6 |
0.408 |
|
| 2011 |
Hakim CH, Li D, Duan D. Monitoring murine skeletal muscle function for muscle gene therapy. Methods in Molecular Biology (Clifton, N.J.). 709: 75-89. PMID 21194022 DOI: 10.1007/978-1-61737-982-6_5 |
0.519 |
|
| 2011 |
Li D, Yue Y, Lai Y, Hakim CH, Duan D. Nitrosative stress elicited by nNOSµ delocalization inhibits muscle force in dystrophin-null mice. The Journal of Pathology. 223: 88-98. PMID 21125668 DOI: 10.1002/Path.2799 |
0.422 |
|
| 2011 |
Bagher P, Duan D, Segal SS. Evidence for impaired neurovascular transmission in a murine model of Duchenne muscular dystrophy. Journal of Applied Physiology (Bethesda, Md. : 1985). 110: 601-9. PMID 21109597 DOI: 10.1152/Japplphysiol.01106.2010 |
0.35 |
|
| 2011 |
Smith BF, Yue Y, Woods PR, Kornegay JN, Shin JH, Williams RR, Duan D. An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 216-31. PMID 20714321 DOI: 10.1038/Labinvest.2010.146 |
0.432 |
|
| 2011 |
Ghosh A, Yue Y, Duan D. Efficient transgene reconstitution with hybrid dual AAV vectors carrying the minimized bridging sequences. Human Gene Therapy. 22: 77-83. PMID 20662564 DOI: 10.1089/Hum.2010.122 |
0.66 |
|
| 2010 |
Lai Y, Yue Y, Duan D. Evidence for the Failure of Adeno-associated Virus Serotype 5 to Package a Viral Genome ≥8.2 kb. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 75-79. PMID 28178552 DOI: 10.1038/mt.2009.256 |
0.373 |
|
| 2010 |
Li D, Yue Y, Duan D. Marginal level dystrophin expression improves clinical outcome in a strain of dystrophin/utrophin double knockout mice. Plos One. 5: e15286. PMID 21187970 DOI: 10.1371/Journal.Pone.0015286 |
0.385 |
|
| 2010 |
Bostick B, Yue Y, Duan D. Gender influences cardiac function in the mdx model of Duchenne cardiomyopathy. Muscle & Nerve. 42: 600-3. PMID 20878741 DOI: 10.1002/Mus.21763 |
0.327 |
|
| 2010 |
Qiao C, Zhang W, Yuan Z, Shin JH, Li J, Jayandharan GR, Zhong L, Srivastava A, Xiao X, Duan D. Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle. Human Gene Therapy. 21: 1343-8. PMID 20497037 DOI: 10.1089/Hum.2010.003 |
0.574 |
|
| 2010 |
Li D, Bareja A, Judge L, Yue Y, Lai Y, Fairclough R, Davies KE, Chamberlain JS, Duan D. Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin. Journal of Cell Science. 123: 2008-13. PMID 20483958 DOI: 10.1242/Jcs.064808 |
0.5 |
|
| 2010 |
Lei B, Zhang K, Yue Y, Ghosh A, Duan D. Adeno-associated virus serotype-9 mediated retinal outer plexiform layer transduction is mainly through the photoreceptors. Advances in Experimental Medicine and Biology. 664: 671-8. PMID 20238072 DOI: 10.1007/978-1-4419-1399-9_77 |
0.599 |
|
| 2010 |
Lai Y, Yue Y, Duan D. Evidence for the failure of adeno-associated virus serotype 5 to package a viral genome > or = 8.2 kb. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 75-9. PMID 19904238 DOI: 10.1038/Mt.2009.256 |
0.473 |
|
| 2010 |
Shin JH, Bostick B, Fine DM, Yue Y, Duan D. Duchenne cardiomyopathy gene therapy Muscle Gene Therapy. 141-162. DOI: 10.1007/978-1-4419-1207-7_9 |
0.381 |
|
| 2010 |
Lai Y, Yue Y, Bostick B, Duan D. Delivering large therapeutic genes for muscle gene therapy Muscle Gene Therapy. 205-218. DOI: 10.1007/978-1-4419-1207-7_12 |
0.484 |
|
| 2009 |
Li D, Lai Y, Yue Y, Rabinovitch PS, Hakim C, Duan D. Ectopic catalase expression in mitochondria by adeno-associated virus enhances exercise performance in mice. Plos One. 4: e6673. PMID 19690612 DOI: 10.1371/Journal.Pone.0006673 |
0.511 |
|
| 2009 |
Ghosh A, Yue Y, Shin JH, Duan D. Systemic Trans-splicing adeno-associated viral delivery efficiently transduces the heart of adult mdx mouse, a model for duchenne muscular dystrophy. Human Gene Therapy. 20: 1319-28. PMID 19627234 DOI: 10.1089/Hum.2009.058 |
0.728 |
|
| 2009 |
Lei B, Zhang K, Yue Y, Ghosh A, Duan D. Adeno-associated virus serotype-9 efficiently transduces the retinal outer plexiform layer. Molecular Vision. 15: 1374-82. PMID 19626133 |
0.608 |
|
| 2009 |
Lai Y, Thomas GD, Yue Y, Yang HT, Li D, Long C, Judge L, Bostick B, Chamberlain JS, Terjung RL, Duan D. Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy. The Journal of Clinical Investigation. 119: 624-35. PMID 19229108 DOI: 10.1172/Jci36612 |
0.487 |
|
| 2009 |
Li D, Long C, Yue Y, Duan D. Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx mice. Human Molecular Genetics. 18: 1209-20. PMID 19131360 DOI: 10.1093/Hmg/Ddp015 |
0.495 |
|
| 2009 |
Bostick B, Yue Y, Long C, Marschalk N, Fine DM, Chen J, Duan D. Cardiac expression of a mini-dystrophin that normalizes skeletal muscle force only partially restores heart function in aged Mdx mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 253-61. PMID 19066599 DOI: 10.1038/Mt.2008.264 |
0.475 |
|
| 2008 |
Yue Y, Ghosh A, Long C, Bostick B, Smith BF, Kornegay JN, Duan D. A single intravenous injection of adeno-associated virus serotype-9 leads to whole body skeletal muscle transduction in dogs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1944-52. PMID 18827804 DOI: 10.1038/Mt.2008.207 |
0.71 |
|
| 2008 |
Duan D. Dystrophin knockdown mice suggest that early, transient dystrophin expression might be enough to prevent later pathology. Neuromuscular Disorders : Nmd. 18: 904-5. PMID 18818078 DOI: 10.1016/J.Nmd.2008.06.371 |
0.531 |
|
| 2008 |
Lai Y, Li D, Yue Y, Duan D. Design of trans-splicing adeno-associated viral vectors for Duchenne muscular dystrophy gene therapy. Methods in Molecular Biology (Clifton, N.J.). 433: 259-75. PMID 18679629 DOI: 10.1007/978-1-59745-237-3_16 |
0.512 |
|
| 2008 |
Bostick B, Yue Y, Lai Y, Long C, Li D, Duan D. Adeno-associated virus serotype-9 microdystrophin gene therapy ameliorates electrocardiographic abnormalities in mdx mice. Human Gene Therapy. 19: 851-6. PMID 18666839 DOI: 10.1089/Hum.2008.058 |
0.574 |
|
| 2008 |
Li D, Yue Y, Duan D. Preservation of muscle force in Mdx3cv mice correlates with low-level expression of a near full-length dystrophin protein. The American Journal of Pathology. 172: 1332-41. PMID 18385524 DOI: 10.2353/Ajpath.2008.071042 |
0.479 |
|
| 2008 |
Ghosh A, Yue Y, Lai Y, Duan D. A hybrid vector system expands adeno-associated viral vector packaging capacity in a transgene-independent manner. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 124-30. PMID 17984978 DOI: 10.1038/Sj.Mt.6300322 |
0.713 |
|
| 2008 |
Bostick B, Yue Y, Long C, Duan D. Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression. Circulation Research. 102: 121-30. PMID 17967782 DOI: 10.1161/Circresaha.107.162982 |
0.432 |
|
| 2007 |
Ghosh A, Yue Y, Long C, Bostick B, Duan D. Efficient Whole-body Transduction with Trans-splicing Adeno-associated Viral Vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1220. PMID 28182924 DOI: 10.1038/sj.mt.6300153 |
0.586 |
|
| 2007 |
Ghosh A, Duan D. Expanding adeno-associated viral vector capacity: a tale of two vectors. Biotechnology & Genetic Engineering Reviews. 24: 165-77. PMID 18059632 DOI: 10.1080/02648725.2007.10648098 |
0.635 |
|
| 2007 |
Bostick B, Ghosh A, Yue Y, Long C, Duan D. Systemic AAV-9 transduction in mice is influenced by animal age but not by the route of administration. Gene Therapy. 14: 1605-9. PMID 17898796 DOI: 10.1038/Sj.Gt.3303029 |
0.709 |
|
| 2007 |
Liu M, Yue Y, Li D, Duan D. Catalase overexpression does not impair extensor digitorum longus muscle function in normal mice. Muscle & Nerve. 36: 833-41. PMID 17696155 DOI: 10.1002/Mus.20874 |
0.515 |
|
| 2007 |
Ghosh A, Yue Y, Long C, Bostick B, Duan D. Efficient whole-body transduction with trans-splicing adeno-associated viral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 750-5. PMID 17264855 DOI: 10.1038/Sj.Mt.6300081 |
0.723 |
|
| 2006 |
Duan D. From the smallest virus to the biggest gene: marching towards gene therapy for duchenne muscular dystrophy. Discovery Medicine. 6: 103-8. PMID 17234143 |
0.361 |
|
| 2006 |
Lai Y, Yue Y, Liu M, Duan D. Synthetic intron improves transduction efficiency of trans-splicing adeno-associated viral vectors. Human Gene Therapy. 17: 1036-42. PMID 17007565 DOI: 10.1089/Hum.2006.17.1036 |
0.495 |
|
| 2006 |
Duan D. Challenges and opportunities in dystrophin-deficient cardiomyopathy gene therapy. Human Molecular Genetics. 15: R253-61. PMID 16987891 DOI: 10.1093/Hmg/Ddl180 |
0.544 |
|
| 2006 |
Yue Y, Liu M, Duan D. C-terminal-truncated microdystrophin recruits dystrobrevin and syntrophin to the dystrophin-associated glycoprotein complex and reduces muscular dystrophy in symptomatic utrophin/dystrophin double-knockout mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 79-87. PMID 16563874 DOI: 10.1016/J.Ymthe.2006.01.007 |
0.552 |
|
| 2006 |
Ghosh A, Yue Y, Duan D. Viral serotype and the transgene sequence influence overlapping adeno-associated viral (AAV) vector-mediated gene transfer in skeletal muscle. The Journal of Gene Medicine. 8: 298-305. PMID 16385549 DOI: 10.1002/Jgm.835 |
0.723 |
|
| 2006 |
Lai Y, Yue Y, Liu M, Duan D. Brief Report: Synthetic Intron Improves Transduction Efficiency ofTrans-Splicing Adeno-associated Viral Vectors Human Gene Therapy. 60928063342004. DOI: 10.1089/Hum.2006.17.Ft-246 |
0.387 |
|
| 2006 |
Ghosh A, Yue Y, Duan D. 740. A Novel Hybrid System Efficiently Expands AAV Packaging Capacity Molecular Therapy. 13: S286. DOI: 10.1016/J.Ymthe.2006.08.822 |
0.509 |
|
| 2006 |
Lai Y, Duan D. 1063. Optimizing Intron Splicing Signal Overcomes the mRNA Accumulation Barrier in Trans-Splicing AAV Vectors Molecular Therapy. 13: S407-S408. DOI: 10.1016/J.Ymthe.2006.08.1161 |
0.35 |
|
| 2005 |
Lai Y, Yue Y, Liu M, Ghosh A, Engelhardt JF, Chamberlain JS, Duan D. Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors. Nature Biotechnology. 23: 1435-9. PMID 16244658 DOI: 10.1038/Nbt1153 |
0.719 |
|
| 2005 |
Liu M, Yue Y, Harper SQ, Grange RW, Chamberlain JS, Duan D. Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 245-56. PMID 15668136 DOI: 10.1016/J.Ymthe.2004.09.013 |
0.521 |
|
| 2005 |
Lai Y, Yue Y, Liu M, Ghosh A, Engelhardt JF, Chamberlain JS, Duan D. 793. Efficient Expression of the 6 kb Mini-Dystrophin Gene by Trans-Splicing Adeno-Associated Viral (AAV) Vector Restores the Entire Dystrophin-Associated Glycoprotein Complex and Reduces Contraction-Induced Damage in the Mdx Mouse Model of Duchenne Muscular Dystrophy Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.353 |
0.548 |
|
| 2005 |
Liu M, Yue Y, Duan D. 688. Adno-Associated Virus (AAV)-Mediated Catalase Overexpression Protects the Extensor Digitorum Longous Muscle from Contraction-Induced Injury Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.228 |
0.508 |
|
| 2005 |
Ghosh A, Yue Y, Duan D. 515. Overlapping Adeno-Associated Viral (AAV) Vector Mediated Gene Transfer Is Dependent on Viral Serotype and the Transgene Sequence in Skeletal Muscle Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.055 |
0.738 |
|
| 2004 |
Rex TS, Tsui I, Hahn P, Maguire AM, Duan D, Bennett J, Dunaief JL. Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress. Human Gene Therapy. 15: 960-7. PMID 15585111 DOI: 10.1089/Hum.2004.15.960 |
0.32 |
|
| 2004 |
Xu Z, Yue Y, Lai Y, Ye C, Qiu J, Pintel DJ, Duan D. Trans-splicing adeno-associated viral vector-mediated gene therapy is limited by the accumulation of spliced mRNA but not by dual vector coinfection efficiency. Human Gene Therapy. 15: 896-905. PMID 15353044 DOI: 10.1089/Hum.2004.15.896 |
0.543 |
|
| 2004 |
Yue Y, Skimming JW, Liu M, Strawn T, Duan D. Full-length dystrophin expression in half of the heart cells ameliorates beta-isoproterenol-induced cardiomyopathy in mdx mice. Human Molecular Genetics. 13: 1669-75. PMID 15190010 DOI: 10.1093/Hmg/Ddh174 |
0.53 |
|
| 2004 |
Yue Y, Skimming JW, Liu M, Fang Y, Strawn T, Duan D. 247. Expressing Full-Length Dystrophin in 50% Cardiomyocytes Corrects Cardiomyopathy in the Mdx Mouse Model for Duchenne Muscular Dystrophy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.188 |
0.442 |
|
| 2004 |
Xu Z, Yue Y, Ye C, Qiu J, Pintel DJ, Duan D. 15. Trans-Splicing Adeno-Associated Viral Vector-Mediated Gene Therapy Is Limited by Transcription across the ITR Junction but Not by Dual Vector Co-Infection Efficiency Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.096 |
0.59 |
|
| 2003 |
Yue Y, Li Z, Harper SQ, Davisson RL, Chamberlain JS, Duan D. Microdystrophin gene therapy of cardiomyopathy restores dystrophin-glycoprotein complex and improves sarcolemma integrity in the mdx mouse heart. Circulation. 108: 1626-32. PMID 12952841 DOI: 10.1161/01.Cir.0000089371.11664.27 |
0.553 |
|
| 2003 |
Yue Y, Duan D. Double strand interaction is the predominant pathway for intermolecular recombination of adeno-associated viral genomes. Virology. 313: 1-7. PMID 12951015 DOI: 10.1016/S0042-6822(03)00432-X |
0.473 |
|
| 2003 |
Li Z, Sharma RV, Duan D, Davisson RL. Adenovirus-mediated gene transfer to adult mouse cardiomyocytes is selectively influenced by culture medium. The Journal of Gene Medicine. 5: 765-72. PMID 12950067 DOI: 10.1002/Jgm.405 |
0.384 |
|
| 2003 |
Duan D, Yue Y, Engelhardt JF. Consequences of DNA-dependent protein kinase catalytic subunit deficiency on recombinant adeno-associated virus genome circularization and heterodimerization in muscle tissue. Journal of Virology. 77: 4751-9. PMID 12663782 DOI: 10.1128/Jvi.77.8.4751-4759.2003 |
0.461 |
|
| 2003 |
Duan D, Yue Y, Engelhardt JF. Dual vector expansion of the recombinant AAV packaging capacity. Methods in Molecular Biology (Clifton, N.J.). 219: 29-51. PMID 12596997 DOI: 10.1385/1-59259-350-X:29 |
0.389 |
|
| 2003 |
Duan D, Yue Y, Yan Z, Engelhardt JF. Trans-splicing vectors expand the packaging limits of adeno-associated virus for gene therapy applications. Methods in Molecular Medicine. 76: 287-307. PMID 12526170 DOI: 10.1385/1-59259-304-6:287 |
0.466 |
|
| 2002 |
Yan Z, Ritchie TC, Duan D, Engelhardt JF. Recombinant AAV-mediated gene delivery using dual vector heterodimerization. Methods in Enzymology. 346: 334-57. PMID 11883078 DOI: 10.1016/S0076-6879(02)46065-X |
0.457 |
|
| 2002 |
Harper SQ, Hauser MA, DelloRusso C, Duan D, Crawford RW, Phelps SF, Harper HA, Robinson AS, Engelhardt JF, Brooks SV, Chamberlain JS. Modular flexibility of dystrophin: implications for gene therapy of Duchenne muscular dystrophy. Nature Medicine. 8: 253-61. PMID 11875496 DOI: 10.1038/Nm0302-253 |
0.57 |
|
| 2001 |
Duan D, Zhang Y, Engelhardt JF. Gene delivery to the airway. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 13.9. PMID 18428257 DOI: 10.1002/0471142905.Hg1309S23 |
0.39 |
|
| 2001 |
Duan D, Yue Y, Engelhardt JF. Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 383-91. PMID 11592843 DOI: 10.1006/Mthe.2001.0456 |
0.502 |
|
| 2001 |
Duan D, Yan Z, Yue Y, Ding W, Engelhardt JF. Enhancement of muscle gene delivery with pseudotyped adeno-associated virus type 5 correlates with myoblast differentiation. Journal of Virology. 75: 7662-71. PMID 11462038 DOI: 10.1128/Jvi.75.16.7662-7671.2001 |
0.591 |
|
| 2000 |
Yan Z, Zhang Y, Duan D, Engelhardt JF. Trans-splicing vectors expand the utility of adeno-associated virus for gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 97: 6716-21. PMID 10841568 DOI: 10.1073/Pnas.97.12.6716 |
0.557 |
|
| 2000 |
Duan D, Yue Y, Yan Z, Yang J, Engelhardt JF. Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus. The Journal of Clinical Investigation. 105: 1573-87. PMID 10841516 DOI: 10.1172/Jci8317 |
0.457 |
|
| 2000 |
Duan D, Yue Y, Yan Z, Engelhardt JF. A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation. Nature Medicine. 6: 595-8. PMID 10802719 DOI: 10.1038/75080 |
0.416 |
|
| 2000 |
Walters RW, Duan D, Engelhardt JF, Welsh MJ. Incorporation of adeno-associated virus in a calcium phosphate coprecipitate improves gene transfer to airway epithelia in vitro and in vivo. Journal of Virology. 74: 535-40. PMID 10590145 DOI: 10.1128/Jvi.74.1.535-540.2000 |
0.403 |
|
| 1999 |
Duan D, Yan Z, Yue Y, Engelhardt JF. Structural analysis of adeno-associated virus transduction circular intermediates. Virology. 261: 8-14. PMID 10484751 DOI: 10.1006/Viro.1999.9821 |
0.348 |
|
| 1999 |
Sanlioglu S, Duan D, Engelhardt JF. Two independent molecular pathways for recombinant adeno-associated virus genome conversion occur after UV-C and E4orf6 augmentation of transduction. Human Gene Therapy. 10: 591-602. PMID 10094202 DOI: 10.1089/10430349950018661 |
0.384 |
|
| 1999 |
Duan D, Sharma P, Dudus L, Zhang Y, Sanlioglu S, Yan Z, Yue Y, Ye Y, Lester R, Yang J, Fisher KJ, Engelhardt JF. Formation of adeno-associated virus circular genomes is differentially regulated by adenovirus E4 ORF6 and E2a gene expression. Journal of Virology. 73: 161-9. PMID 9847318 DOI: 10.1128/Jvi.73.1.161-169.1999 |
0.434 |
|
| 1999 |
Duan D, Li Q, Kao AW, Yue Y, Pessin JE, Engelhardt JF. Dynamin Is Required for Recombinant Adeno-Associated Virus Type 2 Infection Journal of Virology. 73: 10371-10376. DOI: 10.1128/Jvi.73.12.10371-10376.1999 |
0.445 |
|
| 1999 |
Duan D, Sharma P, Dudus L, Zhang Y, Sanlioglu S, Yan Z, Yue Y, Ye Y, Lester R, Yang J, Fisher KJ, Engelhardt JF. Formation of Adeno-Associated Virus Circular Genomes Is Differentially Regulated by Adenovirus E4 ORF6 and E2a Gene Expression Journal of Virology. 73: 161-169. DOI: 10.1128/jvi.73.1.161-169.1999 |
0.321 |
|
| 1998 |
Duan D, Sharma P, Yang J, Yue Y, Dudus L, Zhang Y, Fisher KJ, Engelhardt JF. Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. Journal of Virology. 72: 8568-77. PMID 9765395 DOI: 10.1128/Jvi.72.11.8568-8577.1998 |
0.484 |
|
| 1998 |
Duan D, Sehgal A, Yao J, Engelhardt JF. Lef1 transcription factor expression defines airway progenitor cell targets for in utero gene therapy of submucosal gland in cystic fibrosis. American Journal of Respiratory Cell and Molecular Biology. 18: 750-8. PMID 9618379 DOI: 10.1165/Ajrcmb.18.6.2987 |
0.403 |
|
| 1997 |
Duan D, Fisher KJ, Burda JF, Engelhardt JF. Structural and functional heterogeneity of integrated recombinant AAV genomes. Virus Research. 48: 41-56. PMID 9140193 DOI: 10.1016/S0168-1702(96)01425-6 |
0.384 |
|
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