| Year |
Citation |
Score |
| 2017 |
Tyml K. Vitamin C and Microvascular Dysfunction in Systemic Inflammation. Antioxidants (Basel, Switzerland). 6. PMID 28661424 DOI: 10.3390/Antiox6030049 |
0.376 |
|
| 2016 |
Siddiqui M, Swarbreck S, Shao Q, Secor D, Peng T, Laird DW, Tyml K. Critical Role of Cx40 in Reduced Endothelial Electrical Coupling by Lipopolysaccharide and Hypoxia-Reoxygenation. Journal of Vascular Research. 52: 396-403. PMID 27194161 DOI: 10.1159/000445772 |
0.352 |
|
| 2016 |
Secor D, Swarbreck S, Ellis CG, Sharpe MD, Feng Q, Tyml K. Ascorbate inhibits platelet-endothelial adhesion in an in-vitro model of sepsis via reduced endothelial surface P-selectin expression. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. PMID 26829365 DOI: 10.1097/Mbc.0000000000000528 |
0.333 |
|
| 2015 |
Swarbreck SB, Secor D, Ellis CG, Sharpe MD, Wilson JX, Tyml K. Effect of ascorbate on plasminogen activator inhibitor-1 expression and release from platelets and endothelial cells in an in-vitro model of sepsis. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 26: 436-42. PMID 25730478 DOI: 10.1097/Mbc.0000000000000273 |
0.356 |
|
| 2014 |
Swarbreck S, Secor D, Li F, Gross PL, Ellis CG, Sharpe MD, Wilson JX, Tyml K. Effect of ascorbate on fibrinolytic factors in septic mouse skeletal muscle. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 25: 745-53. PMID 24824492 DOI: 10.1097/Mbc.0000000000000138 |
0.396 |
|
| 2014 |
Swarbreck SB, Secor D, Ellis CG, Sharpe MD, Wilson JX, Tyml K. Short-term effect of ascorbate on bacterial content, plasminogen activator inhibitor-1, and myeloperoxidase in septic mice. The Journal of Surgical Research. 191: 432-40. PMID 24814200 DOI: 10.1016/J.Jss.2014.04.017 |
0.363 |
|
| 2011 |
Tyml K. Critical role for oxidative stress, platelets, and coagulation in capillary blood flow impairment in sepsis. Microcirculation (New York, N.Y. : 1994). 18: 152-62. PMID 21199094 DOI: 10.1111/J.1549-8719.2010.00080.X |
0.339 |
|
| 2011 |
Tyml K. Role of connexins in microvascular dysfunction during inflammation. Canadian Journal of Physiology and Pharmacology. 89: 1-12. PMID 21186372 DOI: 10.1139/y10-099 |
0.327 |
|
| 2010 |
Secor D, Li F, Ellis CG, Sharpe MD, Gross PL, Wilson JX, Tyml K. Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries. Intensive Care Medicine. 36: 1928-34. PMID 20689935 DOI: 10.1007/S00134-010-1969-3 |
0.341 |
|
| 2010 |
Yu G, Bolon M, Laird DW, Tyml K. Hypoxia and reoxygenation-induced oxidant production increase in microvascular endothelial cells depends on connexin40. Free Radical Biology & Medicine. 49: 1008-13. PMID 20541007 DOI: 10.1016/J.Freeradbiomed.2010.06.005 |
0.37 |
|
| 2009 |
McKinnon RL, Bolon ML, Wang HX, Swarbreck S, Kidder GM, Simon AM, Tyml K. Reduction of electrical coupling between microvascular endothelial cells by NO depends on connexin37. American Journal of Physiology. Heart and Circulatory Physiology. 297: H93-H101. PMID 19429814 DOI: 10.1152/Ajpheart.01148.2008 |
0.383 |
|
| 2008 |
Tyml K, Li F, Wilson JX. Septic impairment of capillary blood flow requires nicotinamide adenine dinucleotide phosphate oxidase but not nitric oxide synthase and is rapidly reversed by ascorbate through an endothelial nitric oxide synthase-dependent mechanism. Critical Care Medicine. 36: 2355-62. PMID 18596627 DOI: 10.1097/Ccm.0B013E31818024F6 |
0.366 |
|
| 2008 |
Bolon ML, Peng T, Kidder GM, Tyml K. Lipopolysaccharide plus hypoxia and reoxygenation synergistically reduce electrical coupling between microvascular endothelial cells by dephosphorylating connexin40. Journal of Cellular Physiology. 217: 350-9. PMID 18521823 DOI: 10.1002/Jcp.21505 |
0.366 |
|
| 2008 |
Wu F, Tyml K, Wilson JX. iNOS expression requires NADPH oxidase-dependent redox signaling in microvascular endothelial cells. Journal of Cellular Physiology. 217: 207-14. PMID 18481258 DOI: 10.1002/Jcp.21495 |
0.392 |
|
| 2007 |
McKinnon RL, Lidington D, Tyml K. Ascorbate inhibits reduced arteriolar conducted vasoconstriction in septic mouse cremaster muscle. Microcirculation (New York, N.Y. : 1994). 14: 697-707. PMID 17885995 DOI: 10.1080/10739680701410389 |
0.679 |
|
| 2007 |
Yu G, Peng T, Feng Q, Tyml K. Abrupt reoxygenation of microvascular endothelial cells after hypoxia activates ERK1/2 and JNK1, leading to NADPH oxidase-dependent oxidant production. Microcirculation (New York, N.Y. : 1994). 14: 125-36. PMID 17365667 DOI: 10.1080/10739680601131218 |
0.343 |
|
| 2007 |
Lidington D, Li F, Tyml K. Deletion of neuronal NOS prevents impaired vasodilation in septic mouse skeletal muscle. Cardiovascular Research. 74: 151-8. PMID 17258180 DOI: 10.1016/J.Cardiores.2006.12.022 |
0.697 |
|
| 2007 |
Wu F, Schuster DP, Tyml K, Wilson JX. Ascorbate inhibits NADPH oxidase subunit p47phox expression in microvascular endothelial cells. Free Radical Biology & Medicine. 42: 124-31. PMID 17157199 DOI: 10.1016/J.Freeradbiomed.2006.10.033 |
0.417 |
|
| 2007 |
Bolon ML, Kidder GM, Simon AM, Tyml K. Lipopolysaccharide reduces electrical coupling in microvascular endothelial cells by targeting connexin40 in a tyrosine-, ERK1/2-, PKA-, and PKC-dependent manner. Journal of Cellular Physiology. 211: 159-66. PMID 17149706 DOI: 10.1002/Jcp.20928 |
0.412 |
|
| 2006 |
McKinnon RL, Lidington D, Bolon M, Ouellette Y, Kidder GM, Tyml K. Reduced arteriolar conducted vasoconstriction in septic mouse cremaster muscle is mediated by nNOS-derived NO. Cardiovascular Research. 69: 236-44. PMID 16226732 DOI: 10.1016/J.Cardiores.2005.09.003 |
0.678 |
|
| 2005 |
Tyml K, Li F, Wilson JX. Delayed ascorbate bolus protects against maldistribution of microvascular blood flow in septic rat skeletal muscle. Critical Care Medicine. 33: 1823-8. PMID 16096461 DOI: 10.1097/01.Ccm.0000172548.34622.De |
0.375 |
|
| 2005 |
Bolon ML, Ouellette Y, Li F, Tyml K. Abrupt reoxygenation following hypoxia reduces electrical coupling between endothelial cells of wild-type but not connexin40 null mice in oxidant- and PKA-dependent manner. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1725-7. PMID 16037099 DOI: 10.1096/Fj.04-3446Fje |
0.387 |
|
| 2005 |
Rose K, Ouellette Y, Bolon M, Tyml K. Hypoxia/reoxygenation reduces microvascular endothelial cell coupling by a tyrosine and MAP kinase dependent pathway. Journal of Cellular Physiology. 204: 131-8. PMID 15672421 DOI: 10.1002/Jcp.20283 |
0.374 |
|
| 2004 |
Wu F, Wilson JX, Tyml K. Ascorbate protects against impaired arteriolar constriction in sepsis by inhibiting inducible nitric oxide synthase expression. Free Radical Biology & Medicine. 37: 1282-9. PMID 15451067 DOI: 10.1016/J.Freeradbiomed.2004.06.025 |
0.411 |
|
| 2003 |
Lidington D, Ouellette Y, Li F, Tyml K. Conducted vasoconstriction is reduced in a mouse model of sepsis. Journal of Vascular Research. 40: 149-58. PMID 12808351 DOI: 10.1159/000070712 |
0.712 |
|
| 2003 |
Wu F, Wilson JX, Tyml K. Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 285: R50-6. PMID 12637347 DOI: 10.1152/Ajpregu.00564.2002 |
0.471 |
|
| 2003 |
Tyml K, Anderson D, Lidington D, Ladak HM. A new method for assessing arteriolar diameter and hemodynamic resistance using image analysis of vessel lumen. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1721-8. PMID 12521937 DOI: 10.1152/Ajpheart.00741.2002 |
0.643 |
|
| 2002 |
Lidington D, Tyml K, Ouellette Y. Lipopolysaccharide-induced reductions in cellular coupling correlate with tyrosine phosphorylation of connexin 43. Journal of Cellular Physiology. 193: 373-9. PMID 12384989 DOI: 10.1002/Jcp.10179 |
0.66 |
|
| 2002 |
Lidington D, Ouellette Y, Tyml K. Communication of agonist-induced electrical responses along 'capillaries' in vitro can be modulated by lipopolysaccharide, but not nitric oxide. Journal of Vascular Research. 39: 405-13. PMID 12297703 DOI: 10.1159/000064519 |
0.698 |
|
| 2002 |
Mitchell D, Bihari A, Sandig M, Tyml K. Endothelin-a receptor in rat skeletal muscle microvasculature. Microvascular Research. 64: 179-85. PMID 12074645 DOI: 10.1006/Mvre.2002.2427 |
0.353 |
|
| 2002 |
Korcok J, Wu F, Tyml K, Hammond RR, Wilson JX. Sepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition. Journal of Neurochemistry. 81: 185-93. PMID 12067232 DOI: 10.1046/J.1471-4159.2002.00814.X |
0.367 |
|
| 2002 |
Wu F, Tyml K, Wilson JX. Ascorbate inhibits iNOS expression in endotoxin- and IFN gamma-stimulated rat skeletal muscle endothelial cells. Febs Letters. 520: 122-6. PMID 12044883 DOI: 10.1016/S0014-5793(02)02804-1 |
0.436 |
|
| 2001 |
Armour J, Tyml K, Lidington D, Wilson JX. Ascorbate prevents microvascular dysfunction in the skeletal muscle of the septic rat Journal of Applied Physiology. 90: 795-803. PMID 11181585 DOI: 10.1152/Jappl.2001.90.3.795 |
0.668 |
|
| 2001 |
Wu F, Cepinskas G, Wilson JX, Tyml K. Nitric Oxide Attenuates but Superoxide Enhances iNOS Expression in Endotox in- and IFNγ-Stimulated Skeletal Muscle Endothelial Cells Microcirculation. 8: 415-425. DOI: 10.1111/J.1549-8719.2001.Tb00188.X |
0.448 |
|
| 2000 |
Ouellette Y, Lidington D, Naus CG, Tyml K. A new in vitro model for agonist-induced communication between microvascular endothelial cells Microvascular Research. 60: 222-231. PMID 11078638 DOI: 10.1006/Mvre.2000.2263 |
0.666 |
|
| 2000 |
Lidington D, Ouellette Y, Tyml K. Endotoxin increases intercellular resistance in microvascular endothelial cells by a tyrosine kinase pathway. Journal of Cellular Physiology. 185: 117-125. PMID 10942525 DOI: 10.1002/1097-4652(200010)185:1<117::Aid-Jcp11>3.0.Co;2-7 |
0.694 |
|
| 2000 |
Yu J, Bihari A, Lidington D, Tyml K. Gap junction uncouplers attenuate arteriolar response to distal capillary stimuli. Microvascular Research. 59: 162-168. PMID 10625583 DOI: 10.1006/Mvre.1999.2192 |
0.643 |
|
| 1998 |
Tyml K, Yu J, McCormack DG. Capillary and arteriolar responses to local vasodilators are impaired in a rat model of sepsis. Journal of Applied Physiology (Bethesda, Md. : 1985). 84: 837-44. PMID 9480941 DOI: 10.1152/Jappl.1998.84.3.837 |
0.446 |
|
| 1997 |
Tyml K, Song H, Munoz P, Ouellette Y. Evidence for K+ channels involvement in capillary sensing and for bidirectionality in capillary communication. Microvascular Research. 53: 245-253. PMID 9211402 DOI: 10.1006/Mvre.1997.2013 |
0.343 |
|
| 1997 |
Mitchell D, Yu J, Tyml K. Comparable effects of arteriolar and capillary stimuli on blood flow in rat skeletal muscle Microvascular Research. 53: 22-32. PMID 9056473 DOI: 10.1006/Mvre.1996.1988 |
0.403 |
|
| 1996 |
Mitchell D, Tyml K. Nitric oxide release in rat skeletal muscle capillary American Journal of Physiology-Heart and Circulatory Physiology. 270. PMID 8928876 DOI: 10.1152/Ajpheart.1996.270.5.H1696 |
0.406 |
|
| 1995 |
Tyml K, Mathieu-Costello O, Noble E. Microvascular response to ischemia, and endothelial ultrastructure, in disused skeletal muscle. Microvascular Research. 49: 17-32. PMID 7746162 DOI: 10.1006/Mvre.1995.1003 |
0.432 |
|
| 1995 |
Tyml K, Cheng L. Heterogeneity of Red Blood Cell Velocity in Skeletal Muscle Decreases with Increased Flow Microcirculation. 2: 181-193. PMID 7497170 DOI: 10.3109/10739689509146766 |
0.405 |
|
| 1994 |
Lee JJ, Tyml K, Menkis AH, Novick RJ, McKenzie FN. Evaluation of Pulsatile and Nonpulsatile Flow in Capillaries of Goat Skeletal Muscle Using Intravital Microscopy Microvascular Research. 48: 316-327. PMID 7731396 DOI: 10.1006/Mvre.1994.1058 |
0.317 |
|
| 1994 |
Potter RF, Ellis CG, Tyml K, Groom AC. Effect of superoxide dismutase and 21-aminosteroids (lazaroids) on microvascular perfusion following ischemia-reperfusion in skeletal muscle. International Journal of Microcirculation, Clinical and Experimental / Sponsored by the European Society For Microcirculation. 14: 313-8. PMID 7635646 DOI: 10.1159/000178849 |
0.402 |
|
| 1993 |
Song H, Tyml K. Evidence for sensing and integration of biological signals by the capillary network American Journal of Physiology-Heart and Circulatory Physiology. 265: 1235-1242. PMID 8238410 DOI: 10.1152/Ajpheart.1993.265.4.H1235 |
0.386 |
|
| 1992 |
Tyml K, Mathieu-Costello O, Budreau CH. Distribution of red blood cell velocity in capillary network, and endothelial ultrastructure, in aged rat skeletal muscle. Microvascular Research. 44: 1-13. PMID 1640874 DOI: 10.1016/0026-2862(92)90097-9 |
0.396 |
|
| 1992 |
Dietrich HH, Tyml K. Microvascular flow response to localized application of norepinephrine on capillaries in rat and frog skeletal muscle Microvascular Research. 43: 73-86. PMID 1608342 DOI: 10.1016/0026-2862(92)90007-C |
0.409 |
|
| 1992 |
Dietrich HH, Tyml K. Capillary as a communicating medium in the microvasculature. Microvascular Research. 43: 87-99. PMID 1318992 DOI: 10.1016/0026-2862(92)90008-D |
0.366 |
|
| 1990 |
Tyml K, Mathieu-Costello O, Budreau CH. Microvascular response to ischemia, and tissue structure, in normal and atrophied skeletal muscle. Microvascular Research. 39: 223-239. PMID 2352492 DOI: 10.1016/0026-2862(90)90072-Y |
0.419 |
|
| 1989 |
Tyml K, Ellis CG. Localized Heterogeneity of Red Cell Velocity in Skeletal Muscle at Rest and After Contraction Advances in Experimental Medicine and Biology. 248: 735-743. PMID 2789469 DOI: 10.1007/978-1-4684-5643-1_83 |
0.32 |
|
| 1988 |
Tyml K, Mikulash K. Evidence for increased perfusion heterogeneity in skeletal muscle during reduced flow. Microvascular Research. 35: 316-324. PMID 3260655 DOI: 10.1016/0026-2862(88)90086-6 |
0.34 |
|
| 1986 |
Tyml K. Capillary recruitment and heterogeneity of microvascular flow in skeletal muscle before and after contraction Microvascular Research. 32: 84-98. PMID 3488492 DOI: 10.1016/0026-2862(86)90045-2 |
0.406 |
|
| 1983 |
Safranyos RGA, Ellis CG, Tyml K, Groom AC. Heterogeneity of capillary diameters in skeletal muscle of the frog. Microvascular Research. 26: 151-156. PMID 6604860 DOI: 10.1016/0026-2862(83)90066-3 |
0.326 |
|
| 1981 |
Tyml K, Ellis CG, Safranyos RG, Fraser S, Groom AC. Temporal and spatial distributions of red cell velocity in capillaries of resting skeletal muscle, including estimates of red cell transit times Microvascular Research. 22: 14-31. PMID 6974295 DOI: 10.1016/0026-2862(81)90108-4 |
0.338 |
|
| 1980 |
Tyml K, Sherebrin MH. A method for on-line measurements of red cell velocity in microvessels using computerized frame-by-frame analysis of television images Microvascular Research. 20: 1-8. PMID 7412582 DOI: 10.1016/0026-2862(80)90014-X |
0.326 |
|
| 1980 |
Tyml K, Groom AC. Regulation of blood flow in individual capillaries of resting skeletal muscle in frogs. Microvascular Research. 20: 346-357. PMID 6970878 DOI: 10.1016/0026-2862(80)90063-1 |
0.326 |
|
| 1980 |
Tyml K, Groom AC. Fourier transform analysis of periodic variations of red cell velocity in capillaries of resting skeletal muscle in frogs. Microvascular Research. 20: 9-18. PMID 6968017 DOI: 10.1016/0026-2862(80)90015-1 |
0.33 |
|
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