| Year |
Citation |
Score |
| 2023 |
Boegholm N, Petriman NA, Loureiro-López M, Wang J, Vela MIS, Liu B, Kanie T, Ng R, Jackson PK, Andersen JS, Lorentzen E. The IFT81-IFT74 complex acts as an unconventional RabL2 GTPase-activating protein during intraflagellar transport. The Embo Journal. e111807. PMID 37606072 DOI: 10.15252/embj.2022111807 |
0.794 |
|
| 2023 |
Kostyrko K, Román M, Lee AG, Simpson DR, Dinh PT, Leung SG, Marini KD, Kelly MR, Broyde J, Califano A, Jackson PK, Alejandro Sweet-Cordero E. UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma. Nature Communications. 14: 3966. PMID 37407562 DOI: 10.1038/s41467-023-39591-2 |
0.678 |
|
| 2023 |
Weiss LE, Love JF, Yoon J, Comerci CJ, Milenkovic L, Kanie T, Jackson PK, Stearns T, Gustavsson AK. Single-molecule imaging in the primary cilium. Methods in Cell Biology. 176: 59-83. PMID 37164543 DOI: 10.1016/bs.mcb.2023.01.003 |
0.782 |
|
| 2023 |
Kanie T, Ng R, Abbott KL, Pongs O, Jackson PK. Myristoylated Neuronal Calcium Sensor-1 captures the ciliary vesicle at distal appendages. Biorxiv : the Preprint Server For Biology. PMID 36712037 DOI: 10.1101/2023.01.06.523037 |
0.775 |
|
| 2023 |
Kanie T, Love JF, Fisher SD, Gustavsson AK, Jackson PK. A hierarchical pathway for assembly of the distal appendages that organize primary cilia. Biorxiv : the Preprint Server For Biology. PMID 36711481 DOI: 10.1101/2023.01.06.522944 |
0.789 |
|
| 2023 |
Tang R, Shuldiner EG, Kelly M, Murray CW, Hebert JD, Andrejka L, Tsai MK, Hughes NW, Parker MI, Cai H, Li YC, Wahl GM, Dunbrack RL, Jackson PK, Petrov DA, et al. Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth. Nature Cell Biology. PMID 36635501 DOI: 10.1038/s41556-022-01049-w |
0.672 |
|
| 2023 |
Yang J, Xiao Y, Lidsky PV, Wu CT, Bonser LR, Peng S, Garcia-Knight MA, Tassetto M, Chung CI, Li X, Nakayama T, Lee IT, Nayak JV, Ghias K, Hargett KL, ... ... Jackson PK, et al. Fluorogenic reporter enables identification of compounds that inhibit SARS-CoV-2. Nature Microbiology. 8: 121-134. PMID 36604514 DOI: 10.1038/s41564-022-01288-5 |
0.751 |
|
| 2022 |
Wu CT, Lidsky PV, Xiao Y, Cheng R, Lee IT, Nakayama T, Jiang S, He W, Demeter J, Knight MG, Turn RE, Rojas-Hernandez LS, Ye C, Chiem K, Shon J, ... ... Jackson PK, et al. SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming. Cell. PMID 36580912 DOI: 10.1016/j.cell.2022.11.030 |
0.774 |
|
| 2022 |
Janas JA, Zhang L, Luu JH, Demeter J, Meng L, Marro SG, Mall M, Mooney NA, Schaukowitch K, Ng YH, Yang N, Huang Y, Neumayer G, Gozani O, Elias JE, ... Jackson PK, et al. Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation. Molecular Cell. PMID 36417913 DOI: 10.1016/j.molcel.2022.11.002 |
0.542 |
|
| 2022 |
Porpiglia E, Mai T, Kraft P, Holbrook CA, de Morree A, Gonzalez VD, Hilgendorf KI, Frésard L, Trejo A, Bhimaraju S, Jackson PK, Fantl WJ, Blau HM. Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration. Cell Stem Cell. PMID 36384141 DOI: 10.1016/j.stem.2022.10.009 |
0.757 |
|
| 2022 |
Schmidt HB, Jaafar ZA, Wulff BE, Rodencal JJ, Hong K, Aziz-Zanjani MO, Jackson PK, Leonetti MD, Dixon SJ, Rohatgi R, Brandman O. Oxaliplatin disrupts nucleolar function through biophysical disintegration. Cell Reports. 41: 111629. PMID 36351392 DOI: 10.1016/j.celrep.2022.111629 |
0.522 |
|
| 2022 |
Yao Y, Du Jiang P, Chao BN, Cagdas D, Kubo S, Balasubramaniyam A, Zhang Y, Shadur B, NaserEddin A, Folio LR, Schwarz B, Bohrnsen E, Zheng L, Lynberg M, Gottlieb S, ... ... Jackson PK, et al. GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans. The Journal of Experimental Medicine. 219. PMID 35551368 DOI: 10.1084/jem.20201405 |
0.537 |
|
| 2022 |
Raj N, Wang M, Seoane JA, Zhao RL, Kaiser AM, Moonie NA, Demeter J, Boutelle AM, Kerr CH, Mulligan AS, Moffatt C, Zeng SX, Lu H, Barna M, Curtis C, ... ... Jackson PK, et al. The Mettl3 epitranscriptomic writer amplifies p53 stress responses. Molecular Cell. PMID 35512709 DOI: 10.1016/j.molcel.2022.04.010 |
0.632 |
|
| 2022 |
Palla AR, Hilgendorf KI, Yang AV, Kerr JP, Hinken AC, Demeter J, Kraft P, Mooney NA, Yucel N, Burns DM, Wang YX, Jackson PK, Blau HM. Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging. Nature Communications. 13: 1439. PMID 35301320 DOI: 10.1038/s41467-022-29150-6 |
0.764 |
|
| 2022 |
Murray CW, Brady JJ, Han M, Cai H, Tsai MK, Pierce SE, Cheng R, Demeter J, Feldser DM, Jackson PK, Shackelford DB, Winslow MM. LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer. Nature Communications. 13: 1090. PMID 35228570 DOI: 10.1038/s41467-022-28619-8 |
0.654 |
|
| 2022 |
Mascharak S, Talbott HE, Januszyk M, Griffin M, Chen K, Davitt MF, Demeter J, Henn D, Bonham CA, Foster DS, Mooney N, Cheng R, Jackson PK, Wan DC, Gurtner GC, et al. Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing. Cell Stem Cell. PMID 35077667 DOI: 10.1016/j.stem.2021.12.011 |
0.624 |
|
| 2021 |
Xiao Y, Lidsky PV, Shirogane Y, Aviner R, Wu CT, Li W, Zheng W, Talbot D, Catching A, Doitsh G, Su W, Gekko CE, Nayak A, Ernst JD, Brodsky L, ... ... Jackson PK, et al. A defective viral genome strategy elicits broad protective immunity against respiratory viruses. Cell. PMID 34852237 DOI: 10.1016/j.cell.2021.11.023 |
0.725 |
|
| 2021 |
Nakayama T, Lee IT, Jiang S, Matter MS, Yan CH, Overdevest JB, Wu CT, Goltsev Y, Shih LC, Liao CK, Zhu B, Bai Y, Lidsky P, Xiao Y, Zarabanda D, ... ... Jackson PK, et al. Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers. Cell Reports. Medicine. 100421. PMID 34604819 DOI: 10.1016/j.xcrm.2021.100421 |
0.727 |
|
| 2021 |
Cheng R, Jackson PK. Identifying cancer drivers. Science (New York, N.Y.). 374: 38-39. PMID 34591644 DOI: 10.1126/science.abl9080 |
0.433 |
|
| 2021 |
Li X, Lidsky P, Xiao Y, Wu CT, Garcia-Knight M, Yang J, Nakayama T, Nayak JV, Jackson PK, Andino R, Shu X. Ethacridine inhibits SARS-CoV-2 by inactivating viral particles. Plos Pathogens. 17: e1009898. PMID 34478458 DOI: 10.1371/journal.ppat.1009898 |
0.736 |
|
| 2021 |
Chen CK, Cheng R, Demeter J, Chen J, Weingarten-Gabbay S, Jiang L, Snyder MP, Weissman JS, Segal E, Jackson PK, Chang HY. Structured elements drive extensive circular RNA translation. Molecular Cell. PMID 34437836 DOI: 10.1016/j.molcel.2021.07.042 |
0.706 |
|
| 2021 |
Wu CT, Hilgendorf KI, Bevacqua RJ, Hang Y, Demeter J, Kim SK, Jackson PK. Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion. Genes & Development. PMID 34385262 DOI: 10.1101/gad.348261.121 |
0.771 |
|
| 2021 |
Wu CT, Lidsky PV, Xiao Y, Lee IT, Cheng R, Nakayama T, Jiang S, Demeter J, Bevacqua RJ, Chang CA, Whitener RL, Stalder AK, Zhu B, Chen H, Goltsev Y, ... ... Jackson PK, et al. SARS-CoV-2 infects human pancreatic β cells and elicits β cell impairment. Cell Metabolism. PMID 34081912 DOI: 10.1016/j.cmet.2021.05.013 |
0.764 |
|
| 2021 |
Nano PR, Johnson TK, Kudo T, Mooney NA, Ni J, Demeter J, Jackson PK, Chen JK. Structure-activity mapping of ARHGAP36 reveals regulatory roles for its GAP homology and C-terminal domains. Plos One. 16: e0251684. PMID 33999959 DOI: 10.1371/journal.pone.0251684 |
0.587 |
|
| 2021 |
Chaikovsky AC, Li C, Jeng EE, Loebell S, Lee MC, Murray CW, Cheng R, Demeter J, Swaney DL, Chen SH, Newton BW, Johnson JR, Drainas AP, Shue YT, Seoane JA, ... ... Jackson PK, et al. The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D. Nature. PMID 33854239 DOI: 10.1038/s41586-021-03474-7 |
0.695 |
|
| 2021 |
Kanie T, Jackson PK. Connecting autoimmune disease to Bardet-Biedl syndrome and primary cilia. Embo Reports. e52180. PMID 33511755 DOI: 10.15252/embr.202052180 |
0.754 |
|
| 2020 |
Zaro BW, Noh JJ, Mascetti VL, Demeter J, George B, Zukowska M, Gulati GS, Sinha R, Flynn RA, Banuelos A, Zhang A, Wilkinson AC, Jackson P, Weissman IL. Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells. Elife. 9. PMID 33236985 DOI: 10.7554/eLife.62210 |
0.534 |
|
| 2020 |
Li X, Lidsky P, Xiao Y, Wu CT, Garcia-Knight M, Yang J, Nakayama T, Nayak JV, Jackson PK, Andino R, Shu X. Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models. Biorxiv : the Preprint Server For Biology. PMID 33140048 DOI: 10.1101/2020.10.28.359042 |
0.737 |
|
| 2020 |
Lee IT, Nakayama T, Wu CT, Goltsev Y, Jiang S, Gall PA, Liao CK, Shih LC, Schürch CM, McIlwain DR, Chu P, Borchard NA, Zarabanda D, Dholakia SS, Yang A, ... ... Jackson PK, et al. ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs. Nature Communications. 11: 5453. PMID 33116139 DOI: 10.1038/s41467-020-19145-6 |
0.776 |
|
| 2020 |
Jackson PK. cAMP Signaling in Nanodomains. Cell. 182: 1379-1381. PMID 32946779 DOI: 10.1016/J.Cell.2020.08.041 |
0.31 |
|
| 2020 |
Broyde J, Simpson DR, Murray D, Paull EO, Chu BW, Tagore S, Jones SJ, Griffin AT, Giorgi FM, Lachmann A, Jackson P, Sweet-Cordero EA, Honig B, Califano A. Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses. Nature Biotechnology. PMID 32929263 DOI: 10.1038/S41587-020-0652-7 |
0.327 |
|
| 2020 |
Kelly MR, Kostyrko K, Han K, Mooney NA, Jeng EE, Spees K, Dinh PT, Abbott KL, Gwinn DM, Sweet-Cordero EA, Bassik MC, Jackson PK. Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities. Cancer Discovery. PMID 32727735 DOI: 10.1158/2159-8290.Cd-19-1274 |
0.699 |
|
| 2020 |
Coles GL, Cristea S, Webber JT, Levin RS, Moss SM, He A, Sangodkar J, Hwang YC, Arand J, Drainas AP, Mooney NA, Demeter J, Spradlin JN, Mauch B, Le V, ... ... Jackson PK, et al. Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells. Cancer Cell. PMID 32531271 DOI: 10.1016/J.Ccell.2020.05.003 |
0.628 |
|
| 2020 |
Lee IT, Nakayama T, Wu CT, Goltsev Y, Jiang S, Gall PA, Liao CK, Shih LC, Schurch CM, McIlwain DR, Chu P, Borchard NA, Zarabanda D, Dholakia SS, Yang A, ... ... Jackson PK, et al. Robust ACE2 protein expression localizes to the motile cilia of the respiratory tract epithelia and is not increased by ACE inhibitors or angiotensin receptor blockers. Medrxiv : the Preprint Server For Health Sciences. PMID 32511516 DOI: 10.1101/2020.05.08.20092866 |
0.779 |
|
| 2020 |
Han K, Pierce SE, Li A, Spees K, Anderson GR, Seoane JA, Lo YH, Dubreuil M, Olivas M, Kamber RA, Wainberg M, Kostyrko K, Kelly MR, Yousefi M, Simpkins SW, ... ... Jackson PK, et al. CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities. Nature. 580: 136-141. PMID 32238925 DOI: 10.1038/S41586-020-2099-X |
0.688 |
|
| 2020 |
Bennett HW, Gustavsson AK, Bayas CA, Petrov PN, Mooney N, Moerner WE, Jackson PK. Novel fibrillar structure in the inversin compartment of primary cilia revealed by 3D single-molecule super-resolution microscopy. Molecular Biology of the Cell. mbcE19090499. PMID 31895004 DOI: 10.1091/Mbc.E19-09-0499 |
0.785 |
|
| 2020 |
Kostyrko K, Kelly M, Han K, Jeng E, Morgens D, Bassik M, Jackson P, Sweet-Cordero A. Abstract PR07: Combinatorial knockout of Rap1GDS1 and RhoA leads to lethality in KRAS-driven non-small cell lung cancer Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Ras18-Pr07 |
0.322 |
|
| 2019 |
Hilgendorf KI, Johnson CT, Mezger A, Rice SL, Norris AM, Demeter J, Greenleaf WJ, Reiter JF, Kopinke D, Jackson PK. Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis. Cell. PMID 31761534 DOI: 10.1016/J.Cell.2019.11.005 |
0.762 |
|
| 2019 |
Hsu J, Arand J, Chaikovsky A, Mooney NA, Demeter J, Brison CM, Oliverio R, Vogel H, Rubin SM, Jackson PK, Sage J. E2F4 regulates transcriptional activation in mouse embryonic stem cells independently of the RB family. Nature Communications. 10: 2939. PMID 31270324 DOI: 10.1038/S41467-019-10901-X |
0.717 |
|
| 2019 |
Lin CH, Wang Z, Duque-Afonso J, Wong SH, Demeter J, Loktev AV, Somervaille TCP, Jackson PK, Cleary ML. Oligomeric self-association contributes to E2A-PBX1-mediated oncogenesis. Scientific Reports. 9: 4915. PMID 30894657 DOI: 10.1038/S41598-019-41393-W |
0.618 |
|
| 2018 |
Kanie T, Jackson PK. Guanine Nucleotide Exchange Assay Using Fluorescent MANT-GDP. Bio-Protocol. 8. PMID 29951569 DOI: 10.21769/BioProtoc.2795 |
0.761 |
|
| 2018 |
Kelly MR, Han K, Mooney N, Jeng E, Kostyrko K, Sweet-Cordero A, Bassik M, Jackson PK. Abstract PR12: A combined protein-protein interaction and genetic interaction map defines new and critical Kras effectors in non-small cell lung cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-Pr12 |
0.359 |
|
| 2017 |
Qin EY, Cooper DD, Abbott KL, Lennon J, Nagaraja S, Mackay A, Jones C, Vogel H, Jackson PK, Monje M. Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma. Cell. PMID 28823557 DOI: 10.1016/J.Cell.2017.07.016 |
0.317 |
|
| 2017 |
Kanie T, Abbott KL, Mooney NA, Plowey ED, Demeter J, Jackson PK. The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Developmental Cell. PMID 28625565 DOI: 10.1016/J.Devcel.2017.05.016 |
0.797 |
|
| 2017 |
Li B, Ding S, Feng N, Mooney N, Ooi YS, Ren L, Diep J, Kelly MR, Yasukawa LL, Patton JT, Yamazaki H, Shirao T, Jackson PK, Greenberg HB. Drebrin restricts rotavirus entry by inhibiting dynamin-mediated endocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416666 DOI: 10.1073/Pnas.1619266114 |
0.736 |
|
| 2017 |
Kelly MR, Kyuho H, Jeng EE, Morgans D, Kostyrko K, Simpson D, Gwinn D, Sweet-Cordero A, Bassik MC, Jackson PK. Abstract PR03: Linking AP/MS-driven protein-protein interaction networks and combination CRISPR/sgRNA screens defines new Kras effectors and target candidates for non-small cell lung cancer Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Pr03 |
0.345 |
|
| 2016 |
Ding S, Mooney N, Li B, Kelly MR, Feng N, Loktev AV, Sen A, Patton JT, Jackson PK, Greenberg HB. Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. Plos Pathogens. 12: e1005929. PMID 27706223 DOI: 10.1371/Journal.Ppat.1005929 |
0.72 |
|
| 2016 |
Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun DA, Pierquin G, Biver A, Wagner K, ... ... Jackson PK, et al. Corrigendum: The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. Nature Genetics. 48: 970. PMID 27463398 DOI: 10.1038/Ng0816-970B |
0.688 |
|
| 2016 |
Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun D, Pierquin G, Biver A, Wagner K, ... ... Jackson PK, et al. The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. Nature Genetics. PMID 27158779 DOI: 10.1038/Ng.3558 |
0.739 |
|
| 2016 |
Pal K, Hwang SH, Somatilaka B, Badgandi H, Jackson PK, DeFea K, Mukhopadhyay S. Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. The Journal of Cell Biology. PMID 27002170 DOI: 10.1083/Jcb.201506132 |
0.554 |
|
| 2016 |
Hilgendorf KI, Johnson CT, Jackson PK. The primary cilium as a cellular receiver: organizing ciliary GPCR signaling. Current Opinion in Cell Biology. 39: 84-92. PMID 26926036 DOI: 10.1016/J.Ceb.2016.02.008 |
0.775 |
|
| 2015 |
Gholkar AA, Senese S, Lo YC, Capri J, Deardorff WJ, Dharmarajan H, Contreras E, Hodara E, Whitelegge JP, Jackson PK, Torres JZ. Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis. Cell Cycle (Georgetown, Tex.). 14: 1116-25. PMID 25830415 DOI: 10.4161/15384101.2014.985066 |
0.517 |
|
| 2015 |
Broyde J, Simpson D, Wah DA, Giorgi FM, Petrey D, Alvarez MJ, Silkov A, Lachmann A, Hill DE, Vidal M, Jackson P, Honig B, Sweet-Cordero A, Califano A. Abstract PR13: Systems and structural biology approaches to elucidate new effectors in KRAS mutant tumors Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr13 |
0.328 |
|
| 2015 |
Acharya S, Petersen KYD, Golubkov V, Kwong M, Adams CM, Jackson PK, Lewis DB. Abstract 5002: Abstract Submission Cancer Research. 75: 5002-5002. DOI: 10.1158/1538-7445.Am2015-5002 |
0.344 |
|
| 2014 |
Del Nagro CJ, Choi J, Xiao Y, Rangell L, Mohan S, Pandita A, Zha J, Jackson PK, O'Brien T. Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death. Cell Cycle (Georgetown, Tex.). 13: 303-14. PMID 24247149 DOI: 10.4161/Cc.27055 |
0.34 |
|
| 2014 |
Thomas S, Wright KJ, Le Corre S, Micalizzi A, Romani M, Abhyankar A, Saada J, Perrault I, Amiel J, Litzler J, Filhol E, Elkhartoufi N, Kwong M, Casanova JL, Boddaert N, ... ... Jackson PK, et al. A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium. Human Mutation. 35: 137-46. PMID 24166846 DOI: 10.1002/Humu.22470 |
0.319 |
|
| 2013 |
Xiao Y, Elkins K, Durieux JK, Lee L, Oeh J, Yang LX, Liang X, DelNagro C, Tremayne J, Kwong M, Liederer BM, Jackson PK, Belmont LD, Sampath D, O'Brien T. Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618. Neoplasia (New York, N.Y.). 15: 1151-60. PMID 24204194 DOI: 10.1593/Neo.131304 |
0.311 |
|
| 2013 |
Xiao Y, Ramiscal J, Kowanetz K, Del Nagro C, Malek S, Evangelista M, Blackwood E, Jackson PK, O'Brien T. Identification of preferred chemotherapeutics for combining with a CHK1 inhibitor. Molecular Cancer Therapeutics. 12: 2285-95. PMID 24038068 DOI: 10.1158/1535-7163.Mct-13-0404 |
0.313 |
|
| 2013 |
Magnaghi P, D'Alessio R, Valsasina B, Avanzi N, Rizzi S, Asa D, Gasparri F, Cozzi L, Cucchi U, Orrenius C, Polucci P, Ballinari D, Perrera C, Leone A, Cervi G, ... ... Jackson PK, et al. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death. Nature Chemical Biology. 9: 548-56. PMID 23892893 DOI: 10.1038/Nchembio.1313 |
0.347 |
|
| 2013 |
Blackwood E, Epler J, Yen I, Flagella M, O'Brien T, Evangelista M, Schmidt S, Xiao Y, Choi J, Kowanetz K, Ramiscal J, Wong K, Jakubiak D, Yee S, Cain G, ... ... Jackson PK, et al. Combination drug scheduling defines a "window of opportunity" for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900. Molecular Cancer Therapeutics. 12: 1968-80. PMID 23873850 DOI: 10.1158/1535-7163.Mct-12-1218 |
0.348 |
|
| 2013 |
Mukhopadhyay S, Jackson PK. Cilia, tubby mice, and obesity. Cilia. 2: 1. PMID 23351214 DOI: 10.1186/2046-2530-2-1 |
0.476 |
|
| 2013 |
Mukhopadhyay S, Wen X, Ratti N, Loktev A, Rangell L, Scales SJ, Jackson PK. The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell. 152: 210-23. PMID 23332756 DOI: 10.1016/J.Cell.2012.12.026 |
0.556 |
|
| 2013 |
Lahtela J, Corson LB, Hemmes A, Brauer MJ, Koopal S, Lee J, Hunsaker TL, Jackson PK, Verschuren EW. A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. Cell Cycle (Georgetown, Tex.). 12: 625-34. PMID 23324396 DOI: 10.4161/Cc.23515 |
0.315 |
|
| 2013 |
Polucci P, Magnaghi P, Angiolini M, Asa D, Avanzi N, Badari A, Bertrand J, Casale E, Cauteruccio S, Cirla A, Cozzi L, Galvani A, Jackson PK, Liu Y, Magnuson S, et al. Alkylsulfanyl-1,2,4-triazoles, a new class of allosteric valosine containing protein inhibitors. Synthesis and structure-activity relationships. Journal of Medicinal Chemistry. 56: 437-50. PMID 23245311 DOI: 10.1021/Jm3013213 |
0.342 |
|
| 2012 |
Beales P, Jackson PK. Cilia - the prodigal organelle. Cilia. 1: 1. PMID 23351984 DOI: 10.1186/2046-2530-1-1 |
0.307 |
|
| 2012 |
Jackson PK. Cilia develop long-lasting contacts, with other cilia. Cilia. 1: 5. PMID 23351843 DOI: 10.1186/2046-2530-1-5 |
0.341 |
|
| 2012 |
Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, ... ... Jackson PK, et al. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 5299-304. PMID 22431598 DOI: 10.1073/Pnas.1116510109 |
0.62 |
|
| 2012 |
Magnaghi P, D'Alessio R, Valsasina B, Avanzi NR, Rizzi S, Asa D, Gasparri F, Cozzi L, Cucchi U, Orrenius C, Polucci P, Ballinari D, Perrera C, Leone A, Cervi G, ... ... Jackson PK, et al. Abstract 2940: Identification of potent VCP/p97/CDC48 inhibitors with distinct biochemical mechanisms including a reversible, allosteric inhibitor that activates the unfolded protein response, induce autophagy and cancer cell death Cancer Research. 72: 2940-2940. DOI: 10.1158/1538-7445.Am2012-2940 |
0.386 |
|
| 2011 |
Torres JZ, Summers MK, Peterson D, Brauer MJ, Lee J, Senese S, Gholkar AA, Lo YC, Lei X, Jung K, Anderson DC, Davis DP, Belmont L, Jackson PK. The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly. Cell. 147: 1309-23. PMID 22153075 DOI: 10.1016/J.Cell.2011.11.020 |
0.708 |
|
| 2011 |
Wright KJ, Baye LM, Olivier-Mason A, Mukhopadhyay S, Sang L, Kwong M, Wang W, Pretorius PR, Sheffield VC, Sengupta P, Slusarski DC, Jackson PK. An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium. Genes & Development. 25: 2347-60. PMID 22085962 DOI: 10.1101/Gad.173443.111 |
0.652 |
|
| 2011 |
Anderson DJ, Durieux JK, Song K, Alvarado R, Jackson PK, Hatzivassiliou G, Ludlam MJ. Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics. Plos One. 6: e22607. PMID 21829637 DOI: 10.1371/Journal.Pone.0022607 |
0.355 |
|
| 2011 |
Mukhopadhyay S, Jackson PK. The tubby family proteins. Genome Biology. 12: 225. PMID 21722349 DOI: 10.1186/Gb-2011-12-6-225 |
0.546 |
|
| 2011 |
Huang X, Summers MK, Pham V, Lill JR, Liu J, Lee G, Kirkpatrick DS, Jackson PK, Fang G, Dixit VM. Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry. Molecular Cell. 42: 511-23. PMID 21596315 DOI: 10.1016/J.Molcel.2011.03.027 |
0.777 |
|
| 2011 |
Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, ... ... Jackson PK, et al. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 145: 513-28. PMID 21565611 DOI: 10.1016/J.Cell.2011.04.019 |
0.49 |
|
| 2011 |
Jackson PK. Do cilia put brakes on the cell cycle? Nature Cell Biology. 13: 340-2. PMID 21460803 DOI: 10.1038/Ncb0411-340 |
0.322 |
|
| 2011 |
Wertz IE, Kusam S, Lam C, Okamoto T, Sandoval W, Anderson DJ, Helgason E, Ernst JA, Eby M, Liu J, Belmont LD, Kaminker JS, O'Rourke KM, Pujara K, Kohli PB, ... ... Jackson PK, et al. Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7. Nature. 471: 110-4. PMID 21368834 DOI: 10.1038/Nature09779 |
0.365 |
|
| 2011 |
Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK. Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Proceedings of the National Academy of Sciences of the United States of America. 108: 2759-64. PMID 21273506 DOI: 10.1073/Pnas.1018823108 |
0.667 |
|
| 2011 |
Chu CW, Hou F, Zhang J, Phu L, Loktev AV, Kirkpatrick DS, Jackson PK, Zhao Y, Zou H. A novel acetylation of β-tubulin by San modulates microtubule polymerization via down-regulating tubulin incorporation. Molecular Biology of the Cell. 22: 448-56. PMID 21177827 DOI: 10.1091/Mbc.E10-03-0203 |
0.321 |
|
| 2011 |
Maurer T, Garrenton L, Oh A, Pitts K, Skelton N, Fauber B, Pan B, Malek S, Stokoe D, Bowman K, Wu J, Giannetti A, Starovasnik M, Mellman I, Jackson P, et al. Abstract 4759: Drugging the undruggable: Small molecule inhibition of the Ras oncoprotein Cancer Research. 72: 4759-4759. DOI: 10.1158/1538-7445.Am2012-4759 |
0.628 |
|
| 2011 |
Jackson PK. Abstract SY14-02: From disease genetics to diagnostics to functional biology: High-throughput proteomics and protein interaction network building guides discovery of novel disease genes in ciliopathies, cystic disease, and cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy14-02 |
0.357 |
|
| 2011 |
Fang G, Maurer T, Garrenton L, Skelton N, Fauber B, Malek S, Giannetti A, Jackson P, Rudolph J, Wang W. Drugging the Undruggable Small-molecule Inhibition of Ras Oncoprotein European Journal of Cancer. 47: 9. DOI: 10.1016/S0959-8049(11)70114-9 |
0.564 |
|
| 2010 |
Peart MJ, Poyurovsky MV, Kass EM, Urist M, Verschuren EW, Summers MK, Jackson PK, Prives C. APC/C(Cdc20) targets E2F1 for degradation in prometaphase. Cell Cycle (Georgetown, Tex.). 9: 3956-64. PMID 20948288 DOI: 10.4161/Cc.9.19.13162 |
0.657 |
|
| 2010 |
Mukhopadhyay S, Wen X, Chih B, Nelson CD, Lane WS, Scales SJ, Jackson PK. TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Genes & Development. 24: 2180-93. PMID 20889716 DOI: 10.1101/Gad.1966210 |
0.554 |
|
| 2010 |
Peterson D, Lee J, Lei XC, Forrest WF, Davis DP, Jackson PK, Belmont LD. A chemosensitization screen identifies TP53RK, a kinase that restrains apoptosis after mitotic stress. Cancer Research. 70: 6325-35. PMID 20647325 DOI: 10.1158/0008-5472.Can-10-0015 |
0.312 |
|
| 2010 |
O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, ... ... Jackson PK, ... ... Jackson P, et al. Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. The Journal of Clinical Investigation. 120: 791-802. PMID 20179356 DOI: 10.1172/Jci40076 |
0.328 |
|
| 2010 |
Torres JZ, Ban KH, Jackson PK. A specific form of phospho protein phosphatase 2 regulates anaphase-promoting complex/cyclosome association with spindle poles. Molecular Biology of the Cell. 21: 897-904. PMID 20089842 DOI: 10.1091/Mbc.E09-07-0598 |
0.775 |
|
| 2010 |
Summers MK, Jackson PK. Biochemical Regulation of the Anaphase Promoting Complex Annual Review of Biochemistry. 80: 110301095147058. DOI: 10.1146/Annurev.Biochem.78.072407.171958 |
0.316 |
|
| 2009 |
Jackson PK. Navigating the deubiquitinating proteome with a CompPASS. Cell. 138: 222-4. PMID 19632171 DOI: 10.1016/J.Cell.2009.07.008 |
0.3 |
|
| 2009 |
Summers MK, Jackson PK. Biochemical analysis of the Anaphase Promoting Complex: activities of E2 enzymes and substrate competitive (pseudosubstrate) inhibitors. Methods in Molecular Biology (Clifton, N.J.). 545: 313-30. PMID 19475398 DOI: 10.1007/978-1-60327-993-2_20 |
0.622 |
|
| 2009 |
Torres JZ, Miller JJ, Jackson PK. High-throughput generation of tagged stable cell lines for proteomic analysis. Proteomics. 9: 2888-91. PMID 19405035 DOI: 10.1002/Pmic.200800873 |
0.646 |
|
| 2008 |
Loktev AV, Zhang Q, Beck JS, Searby CC, Scheetz TE, Bazan JF, Slusarski DC, Sheffield VC, Jackson PK, Nachury MV. A BBSome subunit links ciliogenesis, microtubule stability, and acetylation. Developmental Cell. 15: 854-65. PMID 19081074 DOI: 10.1016/J.Devcel.2008.11.001 |
0.67 |
|
| 2008 |
Summers MK, Pan B, Mukhyala K, Jackson PK. The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC. Molecular Cell. 31: 544-56. PMID 18722180 DOI: 10.1016/J.Molcel.2008.07.014 |
0.621 |
|
| 2008 |
Jackson PK. The hunt for cyclin. Cell. 134: 199-202. PMID 18662532 DOI: 10.1016/J.Cell.2008.07.011 |
0.331 |
|
| 2008 |
Tang W, Wu JQ, Guo Y, Hansen DV, Perry JA, Freel CD, Nutt L, Jackson PK, Kornbluth S. Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. Molecular Biology of the Cell. 19: 3536-43. PMID 18550795 DOI: 10.1091/Mbc.E08-04-0417 |
0.647 |
|
| 2008 |
Jackson PK. Stopping replication, at the beginning. Nature Chemical Biology. 4: 331-2. PMID 18488006 DOI: 10.1038/Nchembio0608-331 |
0.354 |
|
| 2008 |
Berdougo E, Nachury MV, Jackson PK, Jallepalli PV. The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells. Cell Cycle (Georgetown, Tex.). 7: 1184-90. PMID 18418058 DOI: 10.4161/Cc.7.9.5792 |
0.693 |
|
| 2008 |
Gütgemann I, Lehman NL, Jackson PK, Longacre TA. Emi1 protein accumulation implicates misregulation of the anaphase promoting complex/cyclosome pathway in ovarian clear cell carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 445-54. PMID 18204430 DOI: 10.1038/Modpathol.3801022 |
0.674 |
|
| 2007 |
Wu JQ, Hansen DV, Guo Y, Wang MZ, Tang W, Freel CD, Tung JJ, Jackson PK, Kornbluth S. Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Proceedings of the National Academy of Sciences of the United States of America. 104: 16564-9. PMID 17881560 DOI: 10.1073/Pnas.0707537104 |
0.803 |
|
| 2007 |
Verschuren EW, Ban KH, Masek MA, Lehman NL, Jackson PK. Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence. Molecular and Cellular Biology. 27: 7955-65. PMID 17875940 DOI: 10.1128/Mcb.00908-07 |
0.81 |
|
| 2007 |
Iwai H, Kim M, Yoshikawa Y, Ashida H, Ogawa M, Fujita Y, Muller D, Kirikae T, Jackson PK, Kotani S, Sasakawa C. A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling. Cell. 130: 611-23. PMID 17719540 DOI: 10.1016/J.Cell.2007.06.043 |
0.354 |
|
| 2007 |
Keck JM, Summers MK, Tedesco D, Ekholm-Reed S, Chuang LC, Jackson PK, Reed SI. Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). The Journal of Cell Biology. 178: 371-85. PMID 17664332 DOI: 10.1083/Jcb.200703202 |
0.646 |
|
| 2007 |
Ban KH, Torres JZ, Miller JJ, Mikhailov A, Nachury MV, Tung JJ, Rieder CL, Jackson PK. The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. Developmental Cell. 13: 29-42. PMID 17609108 DOI: 10.1016/J.Devcel.2007.04.017 |
0.798 |
|
| 2007 |
Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peränen J, Merdes A, Slusarski DC, Scheller RH, Bazan JF, Sheffield VC, Jackson PK. A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell. 129: 1201-13. PMID 17574030 DOI: 10.1016/J.Cell.2007.03.053 |
0.663 |
|
| 2007 |
Lehman NL, Tibshirani R, Hsu JY, Natkunam Y, Harris BT, West RB, Masek MA, Montgomery K, van de Rijn M, Jackson PK. Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. The American Journal of Pathology. 170: 1793-805. PMID 17456782 DOI: 10.2353/Ajpath.2007.060767 |
0.789 |
|
| 2007 |
Tung JJ, Padmanabhan K, Hansen DV, Richter JD, Jackson PK. Translational unmasking of Emi2 directs cytostatic factor arrest in meiosis II. Cell Cycle (Georgetown, Tex.). 6: 725-31. PMID 17361107 DOI: 10.4161/Cc.6.6.3936 |
0.796 |
|
| 2007 |
Hansen DV, Pomerening JR, Summers MK, Miller JJ, Ferrell JE, Jackson PK. Emi2 at the crossroads: where CSF meets MPF. Cell Cycle (Georgetown, Tex.). 6: 732-8. PMID 17361104 DOI: 10.4161/Cc.6.6.3937 |
0.775 |
|
| 2007 |
Wu Q, Guo Y, Yamada A, Perry JA, Wang MZ, Araki M, Freel CD, Tung JJ, Tang W, Margolis SS, Jackson PK, Yamano H, Asano M, Kornbluth S. A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest. Current Biology : Cb. 17: 213-24. PMID 17276914 DOI: 10.1016/J.Cub.2006.12.045 |
0.8 |
|
| 2007 |
Verschuren EW, Jackson PK. Putting transcription repression and protein destruction in pRb's pocket. Developmental Cell. 12: 169-70. PMID 17276331 DOI: 10.1016/J.Devcel.2007.01.015 |
0.363 |
|
| 2007 |
Westlake CJ, Junutula JR, Simon GC, Pilli M, Prekeris R, Scheller RH, Jackson PK, Eldridge AG. Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene. Proceedings of the National Academy of Sciences of the United States of America. 104: 1236-41. PMID 17229837 DOI: 10.1073/Pnas.0610500104 |
0.763 |
|
| 2007 |
Marangos P, Verschuren EW, Chen R, Jackson PK, Carroll J. Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1). The Journal of Cell Biology. 176: 65-75. PMID 17190794 DOI: 10.1083/Jcb.200607070 |
0.402 |
|
| 2006 |
Madgwick S, Hansen DV, Levasseur M, Jackson PK, Jones KT. Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis. The Journal of Cell Biology. 174: 791-801. PMID 16966421 DOI: 10.1083/Jcb.200604140 |
0.623 |
|
| 2006 |
Miller JJ, Summers MK, Hansen DV, Nachury MV, Lehman NL, Loktev A, Jackson PK. Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor. Genes & Development. 20: 2410-20. PMID 16921029 DOI: 10.1101/Gad.1454006 |
0.787 |
|
| 2006 |
Lehman NL, Verschuren EW, Hsu JY, Cherry AM, Jackson PK. Overexpression of the anaphase promoting complex/cyclosome inhibitor Emi1 leads to tetraploidy and genomic instability of p53-deficient cells. Cell Cycle (Georgetown, Tex.). 5: 1569-73. PMID 16861914 DOI: 10.4161/Cc.5.14.2925 |
0.805 |
|
| 2006 |
Jackson PK. Climbing the Greatwall to mitosis. Molecular Cell. 22: 156-7. PMID 16630886 DOI: 10.1016/J.Molcel.2006.04.005 |
0.315 |
|
| 2006 |
Eldridge AG, Loktev AV, Hansen DV, Verschuren EW, Reimann JD, Jackson PK. The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1. Cell. 124: 367-80. PMID 16439210 DOI: 10.1016/J.Cell.2005.10.038 |
0.816 |
|
| 2006 |
Huntzicker EG, Estay IS, Zhen H, Lokteva LA, Jackson PK, Oro AE. Dual degradation signals control Gli protein stability and tumor formation. Genes & Development. 20: 276-81. PMID 16421275 DOI: 10.1101/Gad.1380906 |
0.346 |
|
| 2006 |
Hansen DV, Tung JJ, Jackson PK. CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit. Proceedings of the National Academy of Sciences of the United States of America. 103: 608-13. PMID 16407128 DOI: 10.1073/Pnas.0509549102 |
0.798 |
|
| 2006 |
Eldridge AG, Loktev AV, Hansen DV, Verschuren EW, Reimann JDR, Jackson PK. The Evi5 Oncogene Regulates Cyclin Accumulation by Stabilizing the Anaphase-Promoting Complex Inhibitor Emi1 (DOI:10.1016/j.cell.2005.10.038) Cell. 124: 1301-1302. DOI: 10.1016/j.cell.2006.03.014 |
0.734 |
|
| 2005 |
Lehman NL, van de Rijn M, Jackson PK. Screening of tissue microarrays for ubiquitin proteasome system components in tumors. Methods in Enzymology. 399: 334-55. PMID 16338367 DOI: 10.1016/S0076-6879(05)99023-X |
0.675 |
|
| 2005 |
Casaletto JB, Nutt LK, Wu Q, Moore JD, Etkin LD, Jackson PK, Hunt T, Kornbluth S. Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase. The Journal of Cell Biology. 169: 61-71. PMID 15824132 DOI: 10.1083/Jcb.200411056 |
0.42 |
|
| 2005 |
Tung JJ, Hansen DV, Ban KH, Loktev AV, Summers MK, Adler JR, Jackson PK. A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs. Proceedings of the National Academy of Sciences of the United States of America. 102: 4318-23. PMID 15753281 DOI: 10.1073/Pnas.0501108102 |
0.801 |
|
| 2005 |
Tung JJ, Jackson PK. Emi1 class of proteins regulate entry into meiosis and the meiosis I to meiosis II transition in Xenopus oocytes. Cell Cycle (Georgetown, Tex.). 4: 478-82. PMID 15701974 DOI: 10.4161/Cc.4.3.1532 |
0.797 |
|
| 2004 |
Baumeister W, Bachmair A, Chau V, Cohen R, Coffino P, Demartino G, Deshaies R, Dohmen J, Emr S, Finley D, Hampton R, Hill C, Hochstrasser M, Huber R, Jackson P, et al. Varshavsky's contributions. Science (New York, N.Y.). 306: 1290-2. PMID 15550643 DOI: 10.1126/Science.306.5700.1290 |
0.711 |
|
| 2004 |
Hansen DV, Loktev AV, Ban KH, Jackson PK. Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1. Molecular Biology of the Cell. 15: 5623-34. PMID 15469984 DOI: 10.1091/Mbc.E04-07-0598 |
0.803 |
|
| 2004 |
Pagano M, Jackson PK. Wagging the dogma; tissue-specific cell cycle control in the mouse embryo. Cell. 118: 535-8. PMID 15339658 DOI: 10.1016/J.Cell.2004.08.013 |
0.369 |
|
| 2004 |
Kaiser BK, Nachury MV, Gardner BE, Jackson PK. Xenopus Cdc14 alpha/beta are localized to the nucleolus and centrosome and are required for embryonic cell division. Bmc Cell Biology. 5: 27. PMID 15251038 DOI: 10.1186/1471-2121-5-27 |
0.799 |
|
| 2004 |
Jackson PK. Linking tumor suppression, DNA damage and the anaphase-promoting complex. Trends in Cell Biology. 14: 331-4. PMID 15246424 DOI: 10.1016/J.Tcb.2004.05.005 |
0.373 |
|
| 2003 |
Jackson PK. Can Fizzy fly solo? Nature Cell Biology. 5: 864-5. PMID 14523400 DOI: 10.1038/Ncb1003-864 |
0.326 |
|
| 2003 |
He L, Eldridge AG, Jackson PK, Gunn TM, Barsh GS. Accessory proteins for melanocortin signaling: attractin and mahogunin. Annals of the New York Academy of Sciences. 994: 288-98. PMID 12851328 DOI: 10.1111/J.1749-6632.2003.Tb03192.X |
0.725 |
|
| 2003 |
Margottin-Goguet F, Hsu JY, Loktev A, Hsieh HM, Reimann JD, Jackson PK. Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. Developmental Cell. 4: 813-26. PMID 12791267 DOI: 10.1016/S1534-5807(03)00153-9 |
0.805 |
|
| 2003 |
Guardavaccaro D, Kudo Y, Boulaire J, Barchi M, Busino L, Donzelli M, Margottin-Goguet F, Jackson PK, Yamasaki L, Pagano M. Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo. Developmental Cell. 4: 799-812. PMID 12791266 DOI: 10.1016/S1534-5807(03)00154-0 |
0.682 |
|
| 2003 |
He L, Lu XY, Jolly AF, Eldridge AG, Watson SJ, Jackson PK, Barsh GS, Gunn TM. Spongiform degeneration in mahoganoid mutant mice. Science (New York, N.Y.). 299: 710-2. PMID 12560552 DOI: 10.1126/Science.1079694 |
0.72 |
|
| 2003 |
Jackson PK. Ubiquitinating a phosphorylated Cdk inhibitor on the blades of the Cdc4 beta-propeller. Cell. 112: 142-4. PMID 12553901 DOI: 10.1016/S0092-8674(03)00041-2 |
0.339 |
|
| 2002 |
Borchers AG, Hufton AL, Eldridge AG, Jackson PK, Harland RM, Baker JC. The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development. Developmental Biology. 251: 395-408. PMID 12435366 DOI: 10.1006/Dbio.2002.0814 |
0.735 |
|
| 2002 |
Hansen DV, Hsu JY, Kaiser BK, Jackson PK, Eldridge AG. Control of the centriole and centrosome cycles by ubiquitination enzymes. Oncogene. 21: 6209-21. PMID 12214251 DOI: 10.1038/Sj.Onc.1205824 |
0.785 |
|
| 2002 |
Kaiser BK, Zimmerman ZA, Charbonneau H, Jackson PK. Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase. Molecular Biology of the Cell. 13: 2289-300. PMID 12134069 DOI: 10.1091/Mbc.01-11-0535 |
0.806 |
|
| 2002 |
Jackson PK, Eldridge AG. The SCF ubiquitin ligase: an extended look. Molecular Cell. 9: 923-5. PMID 12049727 DOI: 10.1016/S1097-2765(02)00538-5 |
0.735 |
|
| 2002 |
Hsu JY, Reimann JD, Sørensen CS, Lukas J, Jackson PK. E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1). Nature Cell Biology. 4: 358-66. PMID 11988738 DOI: 10.1038/Ncb785 |
0.8 |
|
| 2002 |
Reimann JD, Jackson PK. Emi1 is required for cytostatic factor arrest in vertebrate eggs. Nature. 416: 850-4. PMID 11976684 DOI: 10.1038/416850A |
0.802 |
|
| 2002 |
Mailand N, Lukas C, Kaiser BK, Jackson PK, Bartek J, Lukas J. Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation. Nature Cell Biology. 4: 317-22. PMID 11901424 DOI: 10.1038/Ncb777 |
0.759 |
|
| 2001 |
Reimann JD, Gardner BE, Margottin-Goguet F, Jackson PK. Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins. Genes & Development. 15: 3278-85. PMID 11751633 DOI: 10.1101/Gad.945701 |
0.391 |
|
| 2001 |
Jackson PK. A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases. Genes & Development. 15: 3053-8. PMID 11731472 DOI: 10.1101/Gad.955501 |
0.351 |
|
| 2001 |
Furstenthal L, Swanson C, Kaiser BK, Eldridge AG, Jackson PK. Triggering ubiquitination of a CDK inhibitor at origins of DNA replication. Nature Cell Biology. 3: 715-22. PMID 11483956 DOI: 10.1038/35087026 |
0.794 |
|
| 2001 |
Reimann JD, Freed E, Hsu JY, Kramer ER, Peters JM, Jackson PK. Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Cell. 105: 645-55. PMID 11389834 DOI: 10.1016/S0092-8674(01)00361-0 |
0.761 |
|
| 2001 |
Furstenthal L, Kaiser BK, Swanson C, Jackson PK. Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication. The Journal of Cell Biology. 152: 1267-78. PMID 11257126 DOI: 10.1083/Jcb.152.6.1267 |
0.795 |
|
| 2000 |
Jackson PK, Eldridge AG, Freed E, Furstenthal L, Hsu JY, Kaiser BK, Reimann JD. The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases. Trends in Cell Biology. 10: 429-39. PMID 10998601 DOI: 10.1016/S0962-8924(00)01834-1 |
0.763 |
|
| 2000 |
Swanson C, Ross J, Jackson PK. Nuclear accumulation of cyclin E/Cdk2 triggers a concentration-dependent switch for the destruction of p27Xic1. Proceedings of the National Academy of Sciences of the United States of America. 97: 7796-801. PMID 10884410 DOI: 10.1073/Pnas.97.14.7796 |
0.644 |
|
| 1999 |
Wolf DA, McKeon F, Jackson PK. Budding yeast Cdc6p induces re-replication in fission yeast by inhibition of SCF(Pop)-mediated proteolysis. Molecular & General Genetics : Mgg. 262: 473-80. PMID 10589835 DOI: 10.1007/S004380051108 |
0.642 |
|
| 1999 |
Freed E, Lacey KR, Huie P, Lyapina SA, Deshaies RJ, Stearns T, Jackson PK. Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle. Genes & Development. 13: 2242-57. PMID 10485847 DOI: 10.1101/Gad.13.17.2242 |
0.713 |
|
| 1999 |
Wolf DA, McKeon F, Jackson PK. F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p. Current Biology : Cb. 9: 373-6. PMID 10209119 DOI: 10.1016/S0960-9822(99)80165-1 |
0.631 |
|
| 1999 |
Lacey KR, Jackson PK, Stearns T. Cyclin-dependent kinase control of centrosome duplication. Proceedings of the National Academy of Sciences of the United States of America. 96: 2817-22. PMID 10077594 DOI: 10.1073/Pnas.96.6.2817 |
0.618 |
|
| 1998 |
Wolf DA, Jackson PK. Cell cycle: oiling the gears of anaphase. Current Biology : Cb. 8: R636-9. PMID 9740795 DOI: 10.1016/S0960-9822(07)00410-1 |
0.375 |
|
| 1996 |
Jackson PK. Cell cycle: Cull and destroy Current Biology. 6: 1209-1212. PMID 8939566 DOI: 10.1016/S0960-9822(96)00697-5 |
0.374 |
|
| 1996 |
Wen ST, Jackson PK, Van Etten RA. The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products Embo Journal. 15: 1583-1595. PMID 8612582 DOI: 10.1002/J.1460-2075.1996.Tb00503.X |
0.391 |
|
| 1995 |
Chen J, Jackson PK, Kirschner MW, Dutta A. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature. 374: 386-8. PMID 7885482 DOI: 10.1038/374386A0 |
0.537 |
|
| 1995 |
Jackson PK, Chevalier S, Philippe M, Kirschner MW. Early events in DNA replication require cyclin E and are blocked by p21CIP1. The Journal of Cell Biology. 130: 755-69. PMID 7642695 DOI: 10.1083/Jcb.130.4.755 |
0.565 |
|
| 1994 |
Van Etten RA, Jackson PK, Baltimore D, Sanders MC, Matsudaira PT, Janmey PA. The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity. The Journal of Cell Biology. 124: 325-40. PMID 8294516 DOI: 10.1083/Jcb.124.3.325 |
0.476 |
|
| 1994 |
Sugiyama H, Wang Y, Jackson P, Sawyers CL, Klein G. Molecular requirements for rapid plasmacytoma and pre-B lymphoma induction by Abelson murine leukemia virus in myc-transgenic mice. International Journal of Cancer. 58: 135-41. PMID 8014009 DOI: 10.1002/Ijc.2910580122 |
0.311 |
|
| 1994 |
King RW, Jackson PK, Kirschner MW. Mitosis in transition. Cell. 79: 563-71. PMID 7954823 DOI: 10.1016/0092-8674(94)90542-8 |
0.589 |
|
| 1993 |
Jackson PK, Paskind M, Baltimore D. Mutation of a phenylalanine conserved in SH3-containing tyrosine kinases activates the transforming ability of c-Abl. Oncogene. 8: 1943-56. PMID 8510937 |
0.417 |
|
| 1993 |
Jackson P, Baltimore D, Picard D. Hormone-conditional transformation by fusion proteins of c-Abl and its transforming variants Embo Journal. 12: 2809-2819. PMID 8334997 DOI: 10.1002/J.1460-2075.1993.Tb05942.X |
0.358 |
|
| 1992 |
Daley GQ, Van Etten RA, Jackson PK, Bernards A, Baltimore D. Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line. Molecular and Cellular Biology. 12: 1864-71. PMID 1549131 DOI: 10.1128/mcb.12.4.1864-1871.1992 |
0.589 |
|
| 1992 |
Mayer BJ, Jackson PK, Van Etten RA, Baltimore D. Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo. Molecular and Cellular Biology. 12: 609-18. PMID 1370711 DOI: 10.1128/Mcb.12.2.609 |
0.522 |
|
| 1991 |
Tybulewicz VLJ, Crawford CE, Jackson PK, Bronson RT, Mulligan RC. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene Cell. 65: 1153-1163. PMID 2065352 DOI: 10.1016/0092-8674(91)90011-M |
0.519 |
|
| 1991 |
Varticovski L, Daley GQ, Jackson P, Baltimore D, Cantley LC. Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants. Molecular and Cellular Biology. 11: 1107-13. PMID 1846663 DOI: 10.1128/Mcb.11.2.1107 |
0.621 |
|
| 1991 |
Mayer BJ, Jackson PK, Baltimore D. The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity. Proceedings of the National Academy of Sciences of the United States of America. 88: 627-31. PMID 1703304 DOI: 10.1073/Pnas.88.2.627 |
0.524 |
|
| 1989 |
Etten RAV, Jackson P, Baltimore D. The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization Cell. 58: 669-678. PMID 2670246 DOI: 10.1016/0092-8674(89)90102-5 |
0.331 |
|
| 1989 |
Jackson P, Baltimore D. N-terminal mutations activate the leukemogenic potential of the myristoylated form of c-abl. The Embo Journal. 8: 449-456. DOI: 10.1002/J.1460-2075.1989.Tb03397.X |
0.468 |
|
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