Douglas P. Mortlock - Publications

Human Genetics Vanderbilt University, Nashville, TN 
Human Development, Genetics

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Pregizer SK, Mortlock DP. Dynamics and cellular localization of Bmp2, Bmp4, and Noggin transcription in the postnatal mouse skeleton. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 64-70. PMID 25043193 DOI: 10.1002/jbmr.2313  0.56
2014 Yutzey KE, Demer LL, Body SC, Huggins GS, Towler DA, Giachelli CM, Hofmann-Bowman MA, Mortlock DP, Rogers MB, Sadeghi MM, Aikawa E. Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2387-93. PMID 25189570 DOI: 10.1161/ATVBAHA.114.302523  0.56
2014 Marsell R, Steen B, Bais MV, Mortlock DP, Einhorn TA, Gerstenfeld LC. Skeletal trauma generates systemic BMP2 activation that is temporally related to the mobilization of CD73+ cells. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 17-23. PMID 24018651 DOI: 10.1002/jor.22487  0.56
2013 Samuels DC, Li C, Li B, Song Z, Torstenson E, Boyd Clay H, Rokas A, Thornton-Wells TA, Moore JH, Hughes TM, Hoffman RD, Haines JL, Murdock DG, Mortlock DP, Williams SM. Recurrent tissue-specific mtDNA mutations are common in humans. Plos Genetics. 9: e1003929. PMID 24244193 DOI: 10.1371/journal.pgen.1003929  0.56
2013 Swinehart IT, Schlientz AJ, Quintanilla CA, Mortlock DP, Wellik DM. Hox11 genes are required for regional patterning and integration of muscle, tendon and bone. Development (Cambridge, England). 140: 4574-82. PMID 24154528 DOI: 10.1242/dev.096693  0.56
2013 Kamiya N, Shafer S, Oxendine I, Mortlock DP, Chandler RL, Oxburgh L, Kim HK. Acute BMP2 upregulation following induction of ischemic osteonecrosis in immature femoral head. Bone. 53: 239-47. PMID 23219944 DOI: 10.1016/j.bone.2012.11.023  0.56
2012 Clendenning DE, Mortlock DP. The BMP ligand Gdf6 prevents differentiation of coronal suture mesenchyme in early cranial development. Plos One. 7: e36789. PMID 22693558 DOI: 10.1371/journal.pone.0036789  1
2012 Ainoya K, Moriguchi T, Ohmori S, Souma T, Takai J, Morita M, Chandler KJ, Mortlock DP, Shimizu R, Engel JD, Lim KC, Yamamoto M. UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice. Molecular and Cellular Biology. 32: 2312-22. PMID 22493062 DOI: 10.1128/MCB.06699-11  0.56
2012 Matsubara H, Hogan DE, Morgan EF, Mortlock DP, Einhorn TA, Gerstenfeld LC. Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis. Bone. 51: 168-80. PMID 22391215 DOI: 10.1016/j.bone.2012.02.017  0.56
2012 Mortlock DP, Pregizer S. Identifying functional annotation for noncoding genomic sequences. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit1.10. PMID 22241655 DOI: 10.1002/0471142905.hg0110s72  0.56
2011 Zuvich RL, Bush WS, McCauley JL, Beecham AH, De Jager PL, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Sawcer SJ, Pericak-Vance MA, Barcellos LF, Mortlock DP, Haines JL. Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex. Human Molecular Genetics. 20: 3517-24. PMID 21653641 DOI: 10.1093/hmg/ddr250  0.56
2011 Kruithof BP, Fritz DT, Liu Y, Garsetti DE, Frank DB, Pregizer SK, Gaussin V, Mortlock DP, Rogers MB. An autonomous BMP2 regulatory element in mesenchymal cells. Journal of Cellular Biochemistry. 112: 666-74. PMID 21268088 DOI: 10.1002/jcb.22975  0.56
2010 Collins PL, Chang S, Henderson M, Soutto M, Davis GM, McLoed AG, Townsend MJ, Glimcher LH, Mortlock DP, Aune TM. Distal regions of the human IFNG locus direct cell type-specific expression. Journal of Immunology (Baltimore, Md. : 1950). 185: 1492-501. PMID 20574006 DOI: 10.4049/jimmunol.1000124  0.56
2010 Jiang S, Chandler RL, Fritz DT, Mortlock DP, Rogers MB. Repressive BMP2 gene regulatory elements near the BMP2 promoter. Biochemical and Biophysical Research Communications. 392: 124-8. PMID 20060812 DOI: 10.1016/j.bbrc.2009.12.157  0.56
2010 Anderson L, Lowery JW, Frank DB, Novitskaya T, Jones M, Mortlock DP, Chandler RL, de Caestecker MP. Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R833-42. PMID 20042692 DOI: 10.1152/ajpregu.00534.2009  0.56
2009 Pregizer S, Mortlock DP. Control of BMP gene expression by long-range regulatory elements. Cytokine & Growth Factor Reviews. 20: 509-15. PMID 19900834 DOI: 10.1016/j.cytogfr.2009.10.011  0.56
2009 Granero-Moltó F, Weis JA, Miga MI, Landis B, Myers TJ, O'Rear L, Longobardi L, Jansen ED, Mortlock DP, Spagnoli A. Regenerative effects of transplanted mesenchymal stem cells in fracture healing. Stem Cells (Dayton, Ohio). 27: 1887-98. PMID 19544445 DOI: 10.1002/stem.103  0.56
2009 Chandler KJ, Chandler RL, Mortlock DP. Identification of an ancient Bmp4 mesoderm enhancer located 46 kb from the promoter. Developmental Biology. 327: 590-602. PMID 19159624 DOI: 10.1016/j.ydbio.2008.12.033  0.56
2008 Luppen CA, Chandler RL, Noh T, Mortlock DP, Frenkel B. BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization. Growth Factors (Chur, Switzerland). 26: 226-37. PMID 19021035 DOI: 10.1080/08977190802277880  0.56
2008 Boyle S, Misfeldt A, Chandler KJ, Deal KK, Southard-Smith EM, Mortlock DP, Baldwin HS, de Caestecker M. Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia. Developmental Biology. 313: 234-45. PMID 18061157 DOI: 10.1016/j.ydbio.2007.10.014  0.56
2007 Chandler KJ, Chandler RL, Broeckelmann EM, Hou Y, Southard-Smith EM, Mortlock DP. Relevance of BAC transgene copy number in mice: transgene copy number variation across multiple transgenic lines and correlations with transgene integrity and expression. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 693-708. PMID 17882484 DOI: 10.1007/s00335-007-9056-y  0.56
2007 McCauley JL, Kenealy SJ, Margulies EH, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Pericak-Vance MA, Haines JL, Mortlock DP. SNPs in Multi-species Conserved Sequences (MCS) as useful markers in association studies: a practical approach. Bmc Genomics. 8: 266. PMID 17683615 DOI: 10.1186/1471-2164-8-266  0.56
2007 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL. TGF-beta signaling is essential for joint morphogenesis. The Journal of Cell Biology. 177: 1105-17. PMID 17576802 DOI: 10.1083/jcb.200611031  0.56
2007 Chandler RL, Chandler KJ, McFarland KA, Mortlock DP. Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter. Molecular and Cellular Biology. 27: 2934-51. PMID 17283059 DOI: 10.1128/MCB.01609-06  0.56
2006 Deal KK, Cantrell VA, Chandler RL, Saunders TL, Mortlock DP, Southard-Smith EM. Distant regulatory elements in a Sox10-βGEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues Developmental Dynamics. 235: 1413-1432. PMID 16586440 DOI: 10.1002/dvdy.20769  0.56
2005 Portnoy ME, McDermott KJ, Antonellis A, Margulies EH, Prasad AB, Kingsley DM, Green ED, Mortlock DP. Detection of potential GDF6 regulatory elements by multispecies sequence comparisons and identification of a skeletal joint enhancer. Genomics. 86: 295-305. PMID 15979840 DOI: 10.1016/j.ygeno.2005.05.003  0.56
2004 Mortlock DP, Portnoy ME, Chandler RL, Green ED. Comparative sequence analysis of the Gdf6 locus reveals a duplicon-mediated chromosomal rearrangement in rodents and rapidly diverging coding and regulatory sequences. Genomics. 84: 814-23. PMID 15475260 DOI: 10.1016/j.ygeno.2004.07.009  0.56
2003 Mortlock DP, Guenther C, Kingsley DM. A general approach for identifying distant regulatory elements applied to the Gdf6 gene. Genome Research. 13: 2069-81. PMID 12915490 DOI: 10.1101/gr.1306003  0.56
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