Michael C. Ostrowski - Publications

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Genetics, Pathology, Oncology, Molecular Biology, Human Development

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Xu L, Fu M, Chen D, Han W, Ostrowski MC, Grossfeld P, Gao P, Ye M. Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition. Bmb Reports. PMID 30670148  0.32
2018 Carey HA, Hildreth BE, Samuvel DJ, Thies KA, Rosol TJ, Toribio RE, Charles JF, Ostrowski MC, Sharma SM. Eomes partners with PU.1 and MITF to Regulate Transcription Factors Critical for osteoclast differentiation. Iscience. 11: 238-245. PMID 30634169 DOI: 10.1016/j.isci.2018.12.018  0.44
2018 Pitarresi JR, Liu X, Avendano A, Thies KA, Sizemore GM, Hammer AM, Hildreth BE, Wang DJ, Steck SA, Donohue S, Cuitiño MC, Kladney RD, Mace TA, Chang JJ, Ennis CS, ... ... Ostrowski MC, et al. Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth. Life Science Alliance. 1: e201800190. PMID 30456390 DOI: 10.26508/lsa.201800190  0.44
2018 Sizemore GM, Balakrishnan S, Thies KA, Hammer AM, Sizemore ST, Trimboli AJ, Cuitiño MC, Steck SA, Tozbikian G, Kladney RD, Shinde N, Das M, Park D, Majumder S, Krishnan S, ... ... Ostrowski MC, et al. Stromal PTEN determines mammary epithelial response to radiotherapy. Nature Communications. 9: 2783. PMID 30018330 DOI: 10.1038/s41467-018-05266-6  0.44
2018 Carey HA, Hildreth BE, Geisler JA, Nickel MC, Cabrera J, Ghosh S, Jiang Y, Yan J, Lee J, Makam S, Young NA, Valiente GR, Jarjour WN, Huang K, Rosol TJ, ... ... Ostrowski MC, et al. Enhancer variants reveal a conserved transcription factor network governed by PU.1 during osteoclast differentiation. Bone Research. 6: 8. PMID 29619268 DOI: 10.1038/s41413-018-0011-1  0.44
2018 Hawley CA, Rojo R, Raper A, Sauter KA, Lisowski ZM, Grabert K, Bain CC, Davis GM, Louwe PA, Ostrowski MC, Hume DA, Pridans C, Jenkins SJ. -mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System. Journal of Immunology (Baltimore, Md. : 1950). PMID 29440354 DOI: 10.4049/jimmunol.1701488  0.4
2016 Pitarresi JR, Liu X, Sharma SM, Cuitiño MC, Kladney RD, Mace TA, Donohue S, Nayak SG, Qu C, Lee J, Woelke SA, Trela S, LaPak K, Yu L, McElroy J, ... ... Ostrowski MC, et al. Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia (New York, N.Y.). 18: 541-52. PMID 27659014 DOI: 10.1016/j.neo.2016.07.006  0.44
2016 Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, ... ... Ostrowski MC, et al. Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. Genes & Development. PMID 27633013 DOI: 10.1101/gad.283499.116  0.72
2015 Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, ... ... Ostrowski MC, et al. Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo. Genes & Development. 29: 1707-20. PMID 26302789 DOI: 10.1101/gad.262568.115  0.72
2015 Carey HA, Bronisz A, Cabrera J, Hildreth BE, Cuitiño M, Fu Q, Ahmad A, Toribio RE, Ostrowski MC, Sharma SM. Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-eyed Mutant. Journal of Cellular Physiology. PMID 26218069 DOI: 10.1002/jcp.25108  0.72
2015 Nair MS, Lee MM, Bonnegarde-Bernard A, Wallace JA, Dean DH, Ostrowski MC, Burry RW, Boyaka PN, Chan MK. Cry protein crystals: a novel platform for protein delivery. Plos One. 10: e0127669. PMID 26030844 DOI: 10.1371/journal.pone.0127669  0.72
2015 Meisen WH, Dubin S, Sizemore ST, Mathsyaraja H, Thies K, Lehman NL, Boyer P, Jaime-Ramirez AC, Elder JB, Powell K, Chakravarti A, Ostrowski MC, Kaur B. Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies. Molecular Cancer Therapeutics. 14: 307-14. PMID 25376607 DOI: 10.1158/1535-7163.MCT-14-0659  0.72
2014 Kabbout M, Dakhlallah D, Sharma S, Bronisz A, Srinivasan R, Piper M, Marsh CB, Ostrowski MC. MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation. Plos One. 9: e100693. PMID 24968297 DOI: 10.1371/journal.pone.0100693  0.72
2014 Wallace JA, Pitarresi JR, Sharma N, Palettas M, Cuitiño MC, Sizemore ST, Yu L, Sanderlin A, Rosol TJ, Mehta KD, Sizemore GM, Ostrowski MC. Protein kinase C Beta in the tumor microenvironment promotes mammary tumorigenesis. Frontiers in Oncology. 4: 87. PMID 24795864 DOI: 10.3389/fonc.2014.00087  0.72
2014 Bronisz A, Wang Y, Nowicki MO, Peruzzi P, Ansari KI, Ogawa D, Balaj L, De Rienzo G, Mineo M, Nakano I, Ostrowski MC, Hochberg F, Weissleder R, Lawler SE, Chiocca EA, et al. Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. Cancer Research. 74: 738-50. PMID 24310399 DOI: 10.1158/0008-5472.CAN-13-2650  0.72
2014 Bronisz A, Carey HA, Godlewski J, Sif S, Ostrowski MC, Sharma SM. The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF) Journal of Biological Chemistry. 289: 326-334. PMID 24257758 DOI: 10.1074/jbc.M113.493874  0.72
2013 Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, ... ... Ostrowski MC, et al. Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. Plos One. 8: e71533. PMID 23977064 DOI: 10.1371/journal.pone.0071533  0.72
2013 Wolford CC, McConoughey SJ, Jalgaonkar SP, Leon M, Merchant AS, Dominick JL, Yin X, Chang Y, Zmuda EJ, O'Toole SA, Millar EK, Roller SL, Shapiro CL, Ostrowski MC, Sutherland RL, et al. Transcription factor ATF3 links host adaptive response to breast cancer metastasis. The Journal of Clinical Investigation. 123: 2893-906. PMID 23921126 DOI: 10.1172/JCI64410  0.72
2013 Peruzzi P, Bronisz A, Nowicki MO, Wang Y, Ogawa D, Price R, Nakano I, Kwon CH, Hayes J, Lawler SE, Ostrowski MC, Chiocca EA, Godlewski J. MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. Neuro-Oncology. 15: 1212-24. PMID 23733246 DOI: 10.1093/neuonc/not055  0.72
2013 Wojton J, Chu Z, Mathsyaraja H, Meisen WH, Denton N, Kwon CH, Chow LM, Palascak M, Franco R, Bourdeau T, Thornton S, Ostrowski MC, Kaur B, Qi X. Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1517-25. PMID 23732993 DOI: 10.1038/mt.2013.114  0.72
2012 Mathsyaraja H, Ostrowski MC. Setting Snail2's pace during EMT Nature Cell Biology. 14: 1122-1123. PMID 23131919 DOI: 10.1038/ncb2616  0.72
2011 Blackwell TS, Hipps AN, Yamamoto Y, Han W, Barham WJ, Ostrowski MC, Yull FE, Prince LS. NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis. Journal of Immunology (Baltimore, Md. : 1950). 187: 2740-7. PMID 21775686 DOI: 10.4049/jimmunol.1101495  0.32
2011 Baran CP, Fischer SN, Nuovo GJ, Kabbout MN, Hitchcock CL, Bringardner BD, McMaken S, Newland CA, Cantemir-Stone CZ, Phillips GS, Ostrowski MC, Marsh CB. Transcription factor ets-2 plays an important role in the pathogenesis of pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 45: 999-1006. PMID 21562315 DOI: 10.1165/rcmb.2010-0490OC  0.72
2011 Wallace JA, Li F, Leone G, Ostrowski MC. Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution. Cancer Research. 71: 1203-7. PMID 21303970 DOI: 10.1158/0008-5472.CAN-10-3263  0.72
2010 Acharyya S, Sharma SM, Cheng AS, Ladner KJ, He W, Kline W, Wang H, Ostrowski MC, Huang TH, Guttridge DC. TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy. Plos One. 5: e12479. PMID 20814569 DOI: 10.1371/journal.pone.0012479  0.72
2010 Godlewski J, Nowicki MO, Bronisz A, Nuovo G, Palatini J, De Lay M, Van Brocklyn J, Ostrowski MC, Chiocca EA, Lawler SE. MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. Molecular Cell. 37: 620-32. PMID 20227367 DOI: 10.1016/j.molcel.2010.02.018  0.72
2010 Zabuawala T, Taffany DA, Sharma SM, Merchant A, Adair B, Srinivasan R, Rosol TJ, Fernandez S, Huang K, Leone G, Ostrowski MC. An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis. Cancer Research. 70: 1323-33. PMID 20145133 DOI: 10.1158/0008-5472.CAN-09-1474  0.44
2009 Srinivasan R, Zabuawala T, Huang H, Zhang J, Gulati P, Fernandez S, Karlo JC, Landreth GE, Leone G, Ostrowski MC. Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis. Plos One. 4: e8283. PMID 20011539 DOI: 10.1371/journal.pone.0008283  0.72
2009 Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, ... ... Ostrowski MC, et al. Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature. 461: 1084-91. PMID 19847259 DOI: 10.1038/nature08486  0.72
2009 Pan F, Yu H, Dang EV, Barbi J, Pan X, Grosso JF, Jinasena D, Sharma SM, McCadden EM, Getnet D, Drake CG, Liu JO, Ostrowski MC, Pardoll DM. Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science (New York, N.Y.). 325: 1142-6. PMID 19696312 DOI: 10.1126/science.1176077  0.72
2009 Wei G, Srinivasan R, Cantemir-Stone CZ, Sharma SM, Santhanam R, Weinstein M, Muthusamy N, Man AK, Oshima RG, Leone G, Ostrowski MC. Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood. 114: 1123-30. PMID 19411629 DOI: 10.1182/blood-2009-03-211391  0.72
2009 Sharma SM, Sif S, Ostrowski MC, Sankar U. Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice. Journal of Cellular Physiology. 220: 230-7. PMID 19288495 DOI: 10.1002/jcp.21755  0.44
2009 Sun Q, Yue P, Deiuliis JA, Lumeng CN, Kampfrath T, Mikolaj MB, Cai Y, Ostrowski MC, Lu B, Parthasarathy S, Brook RD, Moffatt-Bruce SD, Chen LC, Rajagopalan S. Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity. Circulation. 119: 538-46. PMID 19153269 DOI: 10.1161/CIRCULATIONAHA.108.799015  0.72
2009 Joshi T, Ganesan LP, Cheney C, Ostrowski MC, Muthusamy N, Byrd JC, Tridandapani S. The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma. Plos One. 4: e4208. PMID 19148288 DOI: 10.1371/journal.pone.0004208  0.72
2008 Saltz J, Kurc T, Hastings S, Langella S, Oster S, Ervin D, Sharma A, Pan T, Gurcan M, Permar J, Ferreira R, Payne P, Catalyurek U, Caserta E, Leone G, ... Ostrowski MC, et al. e-Science, caGrid, and Translational Biomedical Research. Computer. 41: 58-66. PMID 21311723 DOI: 10.1109/MC.2008.459  0.72
2008 Lin HJ, Zuo T, Lin CH, Kuo CT, Liyanarachchi S, Sun S, Shen R, Deatherage DE, Potter D, Asamoto L, Lin S, Yan PS, Cheng AL, Ostrowski MC, Huang TH. Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Research. 68: 10257-66. PMID 19074894 DOI: 10.1158/0008-5472.CAN-08-0288  0.72
2008 Aliprantis AO, Ueki Y, Sulyanto R, Park A, Sigrist KS, Sharma SM, Ostrowski MC, Olsen BR, Glimcher LH. NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. The Journal of Clinical Investigation. 118: 3775-89. PMID 18846253 DOI: 10.1172/JCI35711  0.72
2008 Hume DA, Sasmono T, Himes SR, Sharma SM, Bronisz A, Constantin M, Ostrowski MC, Ross IL. The ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene Journal of Immunology. 180: 6733-6742. PMID 18453593  0.72
2008 Crotti TN, Sharma SM, Fleming JD, Flannery MR, Ostrowski MC, Goldring SR, McHugh KP. PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter. Journal of Cellular Physiology. 215: 636-44. PMID 18288635 DOI: 10.1002/jcp.21344  0.72
2008 Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Research. 68: 937-45. PMID 18245497 DOI: 10.1158/0008-5472.CAN-07-2148  0.72
2008 Sussan TE, Yang A, Li F, Ostrowski MC, Reeves RH. Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome. Nature. 451: 73-5. PMID 18172498 DOI: 10.1038/nature06446  0.72
2007 Hu R, Sharma SM, Bronisz A, Srinivasan R, Sankar U, Ostrowski MC. Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors. Molecular and Cellular Biology. 27: 4018-27. PMID 17403896 DOI: 10.1128/MCB.01839-06  0.44
2007 Sharma SM, Bronisz A, Hu R, Patel K, Mansky KC, Sif S, Ostrowski MC. MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation. The Journal of Biological Chemistry. 282: 15921-9. PMID 17403683 DOI: 10.1074/jbc.M609723200  0.48
2007 Meadows NA, Sharma SM, Faulkner GJ, Ostrowski MC, Hume DA, Cassady AI. The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor Journal of Biological Chemistry. 282: 1891-1904. PMID 17105730 DOI: 10.1074/jbc.M608572200  0.72
2006 Sharma SM, Hu R, Bronisz A, Meadows N, Lusby T, Fletcher B, Hume DA, Cassady AI, Ostrowski MC. Genetics and genomics of osteoclast differentiation: integrating cell signaling pathways and gene networks. Critical Reviews in Eukaryotic Gene Expression. 16: 253-77. PMID 17073554  0.4
2006 Dai B, Kim O, Xie Y, Guo Z, Xu K, Wang B, Kong X, Melamed J, Chen H, Bieberich CJ, Borowsky AD, Kung HJ, Wei G, Ostrowski MC, Brodie A, et al. Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse. Cancer Research. 66: 8058-64. PMID 16912182 DOI: 10.1158/0008-5472.CAN-06-1364  0.72
2006 Bronisz A, Sharma SM, Hu R, Godlewski J, Tzivion G, Mansky KC, Ostrowski MC. Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors. Molecular Biology of the Cell. 17: 3897-906. PMID 16822840 DOI: 10.1091/mbc.E06-05-0470  0.48
2006 Pengal RA, Ganesan LP, Wei G, Fang H, Ostrowski MC, Tridandapani S. Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt. Molecular Immunology. 43: 1557-64. PMID 16263172 DOI: 10.1016/j.molimm.2005.09.022  0.72
2004 Ganesan LP, Wei G, Pengal RA, Moldovan L, Moldovan N, Ostrowski MC, Tridandapani S. The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase. The Journal of Biological Chemistry. 279: 54416-25. PMID 15485887 DOI: 10.1074/jbc.M408188200  0.72
2004 Wei G, Guo J, Doseff AI, Kusewitt DF, Man AK, Oshima RG, Ostrowski MC. Activated Ets2 is required for persistent inflammatory responses in the motheaten viable model. Journal of Immunology (Baltimore, Md. : 1950). 173: 1374-9. PMID 15240733  0.72
2004 Sankar U, Patel K, Rosol TJ, Ostrowski MC. RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 1339-48. PMID 15231022 DOI: 10.1359/JBMR.040321  0.44
2004 Cao X, Wei G, Fang H, Guo J, Weinstein M, Marsh CB, Ostrowski MC, Tridandapani S. The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages. Journal of Immunology (Baltimore, Md. : 1950). 172: 4851-7. PMID 15067063  0.72
2003 Wei G, Schaffner AE, Baker KM, Mansky KC, Ostrowski MC. Ets-2 interacts with co-repressor BS69 to repress target gene expression. Anticancer Research. 23: 2173-8. PMID 12894593  0.72
2003 Baker KM, Wei G, Schaffner AE, Ostrowski MC. Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter. The Journal of Biological Chemistry. 278: 17876-84. PMID 12637547 DOI: 10.1074/jbc.M209480200  0.72
2003 Wu L, de Bruin A, Saavedra HI, Starovic M, Trimboli A, Yang Y, Opavska J, Wilson P, Thompson JC, Ostrowski MC, Rosol TJ, Woollett LA, Weinstein M, Cross JC, Robinson ML, et al. Extra-embryonic function of Rb is essential for embryonic development and viability. Nature. 421: 942-7. PMID 12607001 DOI: 10.1038/nature01417  0.72
2003 Sasmono RT, Oceandy D, Pollard JW, Tong W, Pavli P, Wainwright BJ, Ostrowski MC, Himes SR, Hume DA. A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood. 101: 1155-63. PMID 12393599 DOI: 10.1182/blood-2002-02-0569  0.72
2002 Weng LP, Brown JL, Baker KM, Ostrowski MC, Eng C. PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway. Human Molecular Genetics. 11: 1687-96. PMID 12095911  0.72
2002 Mansky KC, Sulzbacher S, Purdom G, Nelsen L, Hume DA, Rehli M, Ostrowski MC. The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter Journal of Leukocyte Biology. 71: 304-310. PMID 11818452  0.72
2002 Mansky KC, Marfatia K, Purdom GH, Luchin A, Hume DA, Ostrowski MC. The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts Journal of Leukocyte Biology. 71: 295-303. PMID 11818451  0.72
2002 Mansky KC, Sankar U, Han J, Ostrowski MC. Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling. The Journal of Biological Chemistry. 277: 11077-83. PMID 11792706 DOI: 10.1074/jbc.M111696200  0.48
2000 Smith JL, Schaffner AE, Hofmeister JK, Hartman M, Wei G, Forsthoefel D, Hume DA, Ostrowski MC. ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice. Molecular and Cellular Biology. 20: 8026-34. PMID 11027273  0.72
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