Iva Susan Greenwald - Publications

Genetics and Development Columbia University, New York, NY 
Genetics, Molecular Biology, Human Development

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Luo KL, Underwood RS, Greenwald I. Positive autoregulation of in response to LIN-12 activation in cell fate decisions during reproductive system development. Development (Cambridge, England). PMID 32839181 DOI: 10.1242/Dev.193482  0.68
2019 Deng Y, Luo KL, Shaye DD, Greenwald I. A Screen of the Conserved Kinome for Negative Regulators of LIN-12 Negative Regulatory Region ("NRR")-Missense Activity in . G3 (Bethesda, Md.). PMID 31519743 DOI: 10.1534/G3.119.400471  1
2018 Kim W, Underwood RS, Greenwald I, Shaye DD. OrthoList 2: A New Comparative Genomic Analysis of Human and Genes. Genetics. PMID 30120140 DOI: 10.1534/Genetics.118.301307  1
2017 Underwood R, Deng Y, Greenwald I. Integration of EGFR and LIN-12/Notch Signaling by LIN-1/Elk1, the Cdk8 Kinase Module, and SUR-2/Med23 in Vulval Precursor Cell Fate Patterning in Caenorhabditis elegans. Genetics. PMID 28954762 DOI: 10.1534/Genetics.117.300192  1
2017 de la Cova C, Townley R, Regot S, Greenwald I. A Real-Time Biosensor for ERK Activity Reveals Signaling Dynamics during C. elegans Cell Fate Specification. Developmental Cell. PMID 28826819 DOI: 10.1016/J.Devcel.2017.07.014  1
2017 Sallee MD, Littleford HE, Greenwald I. A bHLH Code for Sexually Dimorphic Form and Function of the C. elegans Somatic Gonad. Current Biology : Cb. PMID 28602651 DOI: 10.1016/J.Cub.2017.05.059  1
2016 Shaye DD, Greenwald I. A network of conserved formins, regulated by the guanine exchange factor EXC-5/FGD and the GTPase Cdc42, modulates tubulogenesis in vivo. Development (Cambridge, England). PMID 27697907 DOI: 10.1242/Dev.141861  1
2016 Deng Y, Greenwald I. Determinants in the LIN-12/Notch Intracellular Domain That Govern Its Activity and Stability During Caenorhabditis elegans Vulval Development. G3 (Bethesda, Md.). PMID 27646703 DOI: 10.1534/G3.116.034363  0.68
2016 Greenwald I. WormBook: WormBiology for the 21st Century. Genetics. 202: 883-4. PMID 26953267 DOI: 10.1534/Genetics.116.187575  0.12
2015 Sallee MD, Aydin T, Greenwald I. Influences of LIN-12/Notch and POP-1/TCF on the Robustness of Ventral Uterine Cell Fate Specification in Caenorhabditis elegans Gonadogenesis. G3 (Bethesda, Md.). 5: 2775-82. PMID 26483009 DOI: 10.1534/g3.115.022608  1
2015 Sallee MD, Greenwald I. Dimerization-driven degradation of C. elegans and human E proteins. Genes & Development. 29: 1356-61. PMID 26159995 DOI: 10.1101/Gad.261917.115  1
2015 Shaye DD, Greenwald I. The disease-associated formin INF2/EXC-6 organizes lumen and cell outgrowth during tubulogenesis by regulating F-actin and microtubule cytoskeletons. Developmental Cell. 32: 743-55. PMID 25771894 DOI: 10.1016/J.Devcel.2015.01.009  1
2015 Chen Y, Greenwald I. hecd-1 modulates notch activity in Caenorhabditis elegans. G3 (Bethesda, Md.). 5: 353-9. PMID 25552605 DOI: 10.1534/G3.114.015321  0.68
2013 Greenwald I, Kovall R. Notch signaling: genetics and structure. Wormbook : the Online Review of C. Elegans Biology. 1-28. PMID 23355521 DOI: 10.1895/Wormbook.1.10.2  0.36
2013 Karp X, Greenwald I. Control of cell-fate plasticity and maintenance of multipotency by DAF-16/FoxO in quiescent Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 110: 2181-6. PMID 23341633 DOI: 10.1073/Pnas.1222377110  1
2012 de la Cova C, Greenwald I. SEL-10/Fbw7-dependent negative feedback regulation of LIN-45/Braf signaling in C. elegans via a conserved phosphodegron. Genes & Development. 26: 2524-35. PMID 23154983 DOI: 10.1101/Gad.203703.112  0.68
2012 Greenwald I. Notch and the awesome power of genetics. Genetics. 191: 655-69. PMID 22785620 DOI: 10.1534/Genetics.112.141812  0.16
2011 Shaye DD, Greenwald I. OrthoList: a compendium of C. elegans genes with human orthologs. Plos One. 6: e20085. PMID 21647448 DOI: 10.1371/Journal.Pone.0020085  1
2011 Zhang X, Greenwald I. Spatial regulation of lag-2 transcription during vulval precursor cell fate patterning in Caenorhabditis elegans. Genetics. 188: 847-58. PMID 21596897 DOI: 10.1534/Genetics.111.128389  0.52
2010 Li J, Greenwald I. LIN-14 inhibition of LIN-12 contributes to precision and timing of C. elegans vulval fate patterning. Current Biology : Cb. 20: 1875-9. PMID 20951046 DOI: 10.1016/J.Cub.2010.09.055  0.64
2010 Choi MS, Yoo AS, Greenwald I. sel-11 and cdc-42, two negative modulators of LIN-12/Notch activity in C. elegans. Plos One. 5: e11885. PMID 20686701 DOI: 10.1371/Journal.Pone.0011885  1
2010 Dunn CD, Sulis ML, Ferrando AA, Greenwald I. A conserved tetraspanin subfamily promotes Notch signaling in Caenorhabditis elegans and in human cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 5907-12. PMID 20220101 DOI: 10.1073/Pnas.1001647107  0.36
2008 Jarriault S, Schwab Y, Greenwald I. A Caenorhabditis elegans model for epithelial-neuronal transdifferentiation. Proceedings of the National Academy of Sciences of the United States of America. 105: 3790-5. PMID 18308937 DOI: 10.1073/Pnas.0712159105  1
2007 Myers TR, Greenwald I. Wnt signal from multiple tissues and lin-3/EGF signal from the gonad maintain vulval precursor cell competence in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 104: 20368-73. PMID 18077322 DOI: 10.1073/Pnas.0709989104  1
2007 de Souza N, Vallier LG, Fares H, Greenwald I. SEL-2, the C. elegans neurobeachin/LRBA homolog, is a negative regulator of lin-12/Notch activity and affects endosomal traffic in polarized epithelial cells. Development (Cambridge, England). 134: 691-702. PMID 17215302 DOI: 10.1242/Dev.02767  1
2006 Katic I, Greenwald I. EMB-4: a predicted ATPase that facilitates lin-12 activity in Caenorhabditis elegans. Genetics. 174: 1907-15. PMID 17030954 DOI: 10.1534/Genetics.106.063453  1
2006 Cui M, Chen J, Myers TR, Hwang BJ, Sternberg PW, Greenwald I, Han M. SynMuv genes redundantly inhibit lin-3/EGF expression to prevent inappropriate vulval induction in C. elegans. Developmental Cell. 10: 667-72. PMID 16678779 DOI: 10.1016/J.Devcel.2006.04.001  1
2005 Greenwald I. LIN-12/Notch signaling in C. elegans. Wormbook : the Online Review of C. Elegans Biology. 1-16. PMID 18050403 DOI: 10.1895/Wormbook.1.10.1  0.16
2005 Yoo AS, Greenwald I. LIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans. Science (New York, N.Y.). 310: 1330-3. PMID 16239437 DOI: 10.1126/Science.1119481  1
2005 Shaye DD, Greenwald I. LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans. Development (Cambridge, England). 132: 5081-92. PMID 16236769 DOI: 10.1242/Dev.02076  1
2005 Jarriault S, Greenwald I. Evidence for functional redundancy between C. elegans ADAM proteins SUP-17/Kuzbanian and ADM-4/TACE. Developmental Biology. 287: 1-10. PMID 16197940 DOI: 10.1016/J.Ydbio.2005.08.014  1
2005 Katic I, Vallier LG, Greenwald I. New positive regulators of lin-12 activity in Caenorhabditis elegans include the BRE-5/Brainiac glycosphingolipid biosynthesis enzyme. Genetics. 171: 1605-15. PMID 16157663 DOI: 10.1534/Genetics.105.048041  1
2005 Patton A, Knuth S, Schaheen B, Dang H, Greenwald I, Fares H. Endocytosis function of a ligand-gated ion channel homolog in Caenorhabditis elegans. Current Biology : Cb. 15: 1045-50. PMID 15936276 DOI: 10.1016/J.Cub.2005.04.057  1
2005 Myers TR, Greenwald I. lin-35 Rb acts in the major hypodermis to oppose ras-mediated vulval induction in C. elegans. Developmental Cell. 8: 117-23. PMID 15621535 DOI: 10.1016/J.Devcel.2004.11.015  1
2004 Karp X, Greenwald I. Multiple roles for the E/Daughterless ortholog HLH-2 during C. elegans gonadogenesis. Developmental Biology. 272: 460-9. PMID 15282161 DOI: 10.1016/J.Ydbio.2004.05.015  1
2004 Chen J, Li X, Greenwald I. sel-7, a positive regulator of lin-12 activity, encodes a novel nuclear protein in Caenorhabditis elegans. Genetics. 166: 151-60. PMID 15020414 DOI: 10.1534/Genetics.166.1.151  1
2004 Chen N, Greenwald I. The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins. Developmental Cell. 6: 183-92. PMID 14960273 DOI: 10.1016/S1534-5807(04)00021-8  0.68
2004 Yu H, Yoo AS, Greenwald I. Cluster Analyzer for Transcription Sites (CATS): a C++-based program for identifying clustered transcription factor binding sites. Bioinformatics (Oxford, England). 20: 1198-200. PMID 14764556 DOI: 10.1093/Bioinformatics/Bth057  1
2004 Yoo AS, Bais C, Greenwald I. Crosstalk between the EGFR and LIN-12/Notch pathways in C. elegans vulval development. Science (New York, N.Y.). 303: 663-6. PMID 14752159 DOI: 10.1126/Science.1091639  1
2003 Karp X, Greenwald I. Post-transcriptional regulation of the E/Daughterless ortholog HLH-2, negative feedback, and birth order bias during the AC/VU decision in C. elegans. Genes & Development. 17: 3100-11. PMID 14701877 DOI: 10.1101/Gad.1160803  1
2003 Jarriault S, Greenwald I. Induction and Lateral Specification Mediated by LIN-12/Notch Proteins Handbook of Cell Signaling. 2: 809-812. DOI: 10.1016/B978-012124546-7/50617-3  1
2002 Shaye DD, Greenwald I. Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans. Nature. 420: 686-90. PMID 12478297 DOI: 10.1038/Nature01234  1
2002 Jarriault S, Greenwald I. Suppressors of the egg-laying defective phenotype of sel-12 presenilin mutants implicate the CoREST corepressor complex in LIN-12/Notch signaling in C. elegans. Genes & Development. 16: 2713-28. PMID 12381669 DOI: 10.1101/Gad.1022402  1
2001 Struhl G, Greenwald I. Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 98: 229-34. PMID 11134525 DOI: 10.1073/Pnas.98.1.229  1
2001 Wen C, Levitan D, Li X, Greenwald I. spr-2, a suppressor of the egg-laying defect caused by loss of sel-12 presenilin in Caenorhabditis elegans, is a member of the SET protein subfamily. Proceedings of the National Academy of Sciences of the United States of America. 97: 14524-9. PMID 11114162 DOI: 10.1073/Pnas.011446498  0.32
2000 Doyle TG, Wen C, Greenwald I. SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 97: 7877-81. PMID 10884418 DOI: 10.1073/Pnas.97.14.7877  0.76
1999 Struhl G, Greenwald I. Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature. 398: 522-5. PMID 10206646 DOI: 10.1038/19091  1
1998 Wu G, Hubbard EJA, Kitajewski JK, Greenwald I. Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin Proceedings of the National Academy of Sciences of the United States of America. 95: 15787-15791. PMID 9861048 DOI: 10.1073/Pnas.95.26.15787  1
1997 Hubbard EJA, Wu G, Kitajewski J, Greenwald I. sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins Genes and Development. 11: 3182-3193. PMID 9389650 DOI: 10.1101/Gad.11.23.3182  1
1996 Levitan D, Doyle TG, Brousseau D, Lee MK, Thinakaran G, Slunt HH, Sisodia SS, Greenwald I. Assessment of normal and mutant human presenilin function in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 93: 14940-4. PMID 8962160 DOI: 10.1073/Pnas.93.25.14940  0.76
1995 Beitel GJ, Tuck S, Greenwald I, Horvitz HR. The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway. Genes & Development. 9: 3149-62. PMID 8543158 DOI: 10.1101/Gad.9.24.3149  1
1993 Seydoux G, Savage C, Greenwald I. Isolation and characterization of mutations causing abnormal eversion of the vulva in Caenorhabditis elegans. Developmental Biology. 157: 423-36. PMID 8500652 DOI: 10.1006/Dbio.1993.1146  1
1993 Struhl G, Fitzgerald K, Greenwald I. Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell. 74: 331-45. PMID 8343960 DOI: 10.1016/0092-8674(93)90424-O  1
1990 Seydoux G, Schedl T, Greenwald I. Cell-cell interactions prevent a potential inductive interaction between soma and germline in C. elegans. Cell. 61: 939-51. PMID 2350786 DOI: 10.1016/0092-8674(90)90060-R  1
1990 Greenwald I. Genetic and molecular analysis of EGF- related genes in Caenorhabditis elegans. Molecular Reproduction and Development. 27: 73-79. PMID 2271190 DOI: 10.1002/Mrd.1080270114  0.36
1990 Greenwald I, Seydoux G. Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans. Nature. 346: 197-9. PMID 2164160 DOI: 10.1038/346197A0  1
1989 Seydoux G, Greenwald I. Cell autonomy of lin-12 function in a cell fate decision in C. elegans. Cell. 57: 1237-45. PMID 2736627 DOI: 10.1016/0092-8674(89)90060-3  1
1987 Greenwald I, Coulson A, Sulston J, Priess J. Correlation of the physical and genetic maps in the lin-12 region of Caenorhabditis elegans. Nucleic Acids Research. 15: 2295-307. PMID 2882468 DOI: 10.1093/Nar/15.5.2295  1
1986 Weston K, Cozens A, Nelson HCM, Fairall L, Amos L, Mengle-Gaw L, Lefebvre FA, Clark MJ, Kenyon C, Bienz M, Breeden L, Schnabel H, Robinson M, Albertson D, Greenwald I, et al. Sexist ads Nature. 321: 106. DOI: 10.1038/321106b0  1
1983 Greenwald IS, Sternberg PW, Horvitz HR. The lin-12 locus specifies cell fates in Caenorhabditis elegans. Cell. 34: 435-44. PMID 6616618 DOI: 10.1016/0092-8674(83)90377-X  1
1983 Horvitz HR, Sternberg PW, Greenwald IS, Fixsen W, Ellis HM. Mutations that affect neural cell lineages and cell fates during the development of the nematode Caenorhabditis elegans. Cold Spring Harbor Symposia On Quantitative Biology. 48: 453-63. PMID 6586368 DOI: 10.1101/Sqb.1983.048.01.050  1
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