Wolfram Goessling - Publications

Affiliations: 
Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Genetics, Human Development

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Schepers AG, Shan J, Cox AG, Huang A, Evans H, Walesky C, Fleming HE, Goessling W, Bhatia SN. Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function. Acs Chemical Biology. PMID 34427427 DOI: 10.1021/acschembio.1c00503  1
2021 Miller BM, Oderberg IM, Goessling W. The Hepatic Nervous System in Development, Regeneration, and Disease. Hepatology (Baltimore, Md.). PMID 34256416 DOI: 10.1002/hep.32055  1
2021 Oderberg IM, Goessling W. Partial Hepatectomy in Adult Zebrafish. Journal of Visualized Experiments : Jove. PMID 33871461 DOI: 10.3791/62349  1
2021 Wrighton PJ, Shwartz A, Heo JM, Quenzer ED, LaBella KA, Harper JW, Goessling W. Quantitative intravital imaging reveals dynamics of physiological-stress induced mitophagy. Journal of Cell Science. PMID 33536245 DOI: 10.1242/jcs.256255  1
2020 Giugliano RP, Gencer B, Wiviott SD, Park JG, Fuchs CS, Goessling W, Musliner TA, Tershakovec AM, Blazing MA, Califf R, Cannon CP, Braunwald E. Prospective Evaluation of Malignancy in 17,708 Patients Randomized to Ezetimibe Versus Placebo: Analysis From IMPROVE-IT. Jacc. Cardiooncology. 2: 385-396. PMID 34396246 DOI: 10.1016/j.jaccao.2020.07.008  1
2020 Walesky CM, Kolb KE, Winston CL, Henderson J, Kruft B, Fleming I, Ko S, Monga SP, Mueller F, Apte U, Shalek AK, Goessling W. Functional compensation precedes recovery of tissue mass following acute liver injury. Nature Communications. 11: 5785. PMID 33214549 DOI: 10.1038/s41467-020-19558-3  0.01
2020 Demy DL, Carrère M, Noche R, Tauzin M, Le Bris M, Baek C, Leshchiner I, Goessling W, Herbomel P. The cationic amino acid exporter Slc7a7 is induced and vital in tissue macrophages with sustained efferocytic activity. Journal of Cell Science. PMID 32973110 DOI: 10.1242/jcs.249037  1
2020 Kochis M, Goessling W. Learning During and From a Crisis: The Student-Led Development of a COVID-19 Curriculum. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 32941252 DOI: 10.1097/ACM.0000000000003755  0.01
2020 Frame JM, Kubaczka C, Long TL, Esain V, Soto RA, Hachimi M, Jing R, Shwartz A, Goessling W, Daley GQ, North TE. Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Developmental Cell. PMID 32810442 DOI: 10.1016/J.Devcel.2020.07.015  1
2020 Zhang Y, Guillermier C, De Raedt T, Cox AG, Maertens O, Yimlamai D, Lun M, Whitney A, Maas RL, Goessling W, Cichowski K, Steinhauser ML. Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity. Iscience. 23: 101355. PMID 32712466 DOI: 10.1016/J.Isci.2020.101355  1
2020 Freeburg SH, Goessling W. Hepatobiliary Differentiation: Principles from Embryonic Liver Development. Seminars in Liver Disease. PMID 32526786 DOI: 10.1055/S-0040-1709679  0.01
2020 Weeks O, Bossé GD, Oderberg IM, Akle S, Houvras Y, Wrighton PJ, LaBella K, Iversen I, Tavakoli S, Adatto I, Schwartz A, Kloosterman D, Tsomides A, Charness ME, Peterson RT, ... ... Goessling W, et al. Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood. The Journal of Clinical Investigation. PMID 32202514 DOI: 10.1172/Jci132139  1
2020 DiNapoli SE, Martinez-McFaline R, Gribbin CK, Wrighton PJ, Balgobin CA, Nelson I, Leonard A, Maskin CR, Shwartz A, Quenzer ED, Mailhiot D, Kao C, McConnell SC, de Jong JLO, Goessling W, et al. Synthetic CRISPR/Cas9 reagents facilitate genome editing and homology directed repair. Nucleic Acids Research. PMID 32064511 DOI: 10.1093/Nar/Gkaa085  1
2020 Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W. Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development. Hepatology (Baltimore, Md.). PMID 32060934 DOI: 10.1002/Hep.31184  1
2020 Lundin V, Sugden WW, Theodore LN, Sousa PM, Han A, Chou S, Wrighton PJ, Cox AG, Ingber DE, Goessling W, Daley GQ, North TE. YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. Developmental Cell. PMID 32032546 DOI: 10.1016/J.Devcel.2020.01.006  1
2020 Goyal L, Chaudhary SP, Kwak EL, Abrams TA, Carpenter AN, Wolpin BM, Wadlow RC, Allen JN, Heist R, McCleary NJ, Chan JA, Goessling W, Schrag D, Ng K, Enzinger PC, et al. A phase 2 clinical trial of the heat shock protein 90 (HSP 90) inhibitor ganetespib in patients with refractory advanced esophagogastric cancer. Investigational New Drugs. PMID 31898183 DOI: 10.1007/S10637-019-00889-Y  1
2019 Shwartz A, Goessling W, Yin C. Macrophages in Zebrafish Models of Liver Diseases. Frontiers in Immunology. 10: 2840. PMID 31867007 DOI: 10.3389/Fimmu.2019.02840  1
2019 Luong P, Li Q, Chen PF, Wrighton PJ, Chang D, Dwyer S, Bayer MT, Snapper SB, Hansen SH, Thiagarajah JT, Goessling W, Lencer WI. A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization. Molecular Biology of the Cell. mbcE19070375. PMID 31774722 DOI: 10.1091/Mbc.E19-07-0375  1
2019 Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wucherpfennig JI, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, ... ... Goessling W, et al. Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer. Nature Genetics. PMID 31406347 DOI: 10.1038/S41588-019-0475-Y  1
2019 Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA. Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development (Cambridge, England). PMID 31160420 DOI: 10.1242/Dev.172387  1
2019 Wrighton PJ, Oderberg IM, Goessling W. There's Something Fishy About Liver Cancer: Zebrafish Models of Hepatocellular Carcinoma. Cellular and Molecular Gastroenterology and Hepatology. PMID 31108233 DOI: 10.1016/J.Jcmgh.2019.05.002  1
2019 Goessling W. Position Is Destiny: Metabolism and Cell Identity. Cell Metabolism. 29: 1017-1019. PMID 31067445 DOI: 10.1016/J.Cmet.2019.04.008  0.01
2019 Chaturantabut S, Shwartz A, Evason KJ, Cox AG, Labella K, Schepers AG, Yang S, Aravena M, Houvras Y, Mancio-Silva L, Romano S, Gorelick DA, Cohen DE, Zon LI, Bhatia SN, ... ... Goessling W, et al. Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. PMID 30641053 DOI: 10.1053/J.Gastro.2019.01.010  1
2019 Soto R, rocha ELd, Vo LT, Hachimi M, Frame JM, Wrighton PJ, Goessling W, Daley GQ, North TE. Ezh1 Inhibits Commitment to Hemogenic Fate and HSPC Formation during Vertebrate Development Blood. 134: 3710-3710. DOI: 10.1182/Blood-2019-131464  1
2019 Soto R, rocha ELd, Wrighton P, Daley G, Goessling W, North T. Investigating The Role Of Ezh1 In Developmental Hematopoiesis Experimental Hematology. 76. DOI: 10.1016/J.Exphem.2019.06.437  1
2018 Cox AG, Tsomides A, Yimlamai D, Hwang KL, Miesfeld J, Galli GG, Fowl BH, Fort M, Ma KY, Sullivan MR, Hosios AM, Snay E, Yuan M, Brown KK, Lien EC, ... ... Goessling W, et al. Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth. The Embo Journal. PMID 30348863 DOI: 10.15252/Embj.2018100294  1
2018 Haghighi A, Krier JB, Toth-Petroczy A, Cassa CA, Frank NY, Carmichael N, Fieg E, Bjonnes A, Mohanty A, Briere LC, Lincoln S, Lucia S, Gupta VA, Söylemez O, Sutti S, ... ... Goessling W, et al. An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery. Npj Genomic Medicine. 3: 21. PMID 30131872 DOI: 10.1038/S41525-018-0060-9  1
2017 Kroeger PT, Drummond BE, Miceli R, McKernan M, Gerlach GF, Marra AN, Fox A, McCampbell KK, Leshchiner I, Rodriguez-Mari A, BreMiller R, Thummel R, Davidson AJ, Postlethwait J, Goessling W, et al. The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development. Developmental Biology. PMID 28579318 DOI: 10.1016/J.Ydbio.2017.05.025  1
2017 Walesky C, Goessling W. WNTing no RASt for HCC. Hepatology (Baltimore, Md.). PMID 28295459 DOI: 10.1002/Hep.29157  1
2017 Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wücherpfennig J, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, ... ... Goessling W, et al. Abstract 4272: Mutations inRABL3alter RAS prenylation and are associated with hereditary pancreatic cancer Epidemiology. 77: 4272-4272. DOI: 10.1158/1538-7445.Am2017-4272  1
2016 North TE, Goessling W. Haematopoietic stem cells show their true colours. Nature Cell Biology. 19: 10-12. PMID 28008181 DOI: 10.1038/Ncb3459  1
2016 Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, ... ... Goessling W, et al. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. Journal of the American Society of Nephrology : Jasn. PMID 27920155 DOI: 10.1681/Asn.2016020131  1
2016 Chu AY, Deng X, Fisher VA, Drong A, Zhang Y, Feitosa MF, Liu CT, Weeks O, Choh AC, Duan Q, Dyer TD, Eicher JD, Guo X, Heard-Costa NL, Kacprowski T, ... ... Goessling W, et al. Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Nature Genetics. PMID 27918534 DOI: 10.1038/Ng.3738  1
2016 Cortes M, Chen MJ, Stachura DL, Liu SY, Kwan W, Wright F, Vo LT, Theodore LN, Esain V, Frost IM, Schlaeger TM, Goessling W, Daley GQ, North TE. Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production. Cell Reports. 17: 458-468. PMID 27705794 DOI: 10.1016/J.Celrep.2016.09.012  1
2016 Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Chang CJ, ... ... Goessling W, et al. Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27588899 DOI: 10.1073/Pnas.1600204113  1
2016 Nissim S, Weeksb O, Talbot JC, Hedgepeth JW, Wucherpfennig J, Schatzman-Bone S, Swinburne I, Cortes M, Alexa K, Megason S, North TE, Amacher SL, Goessling W. Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development. Developmental Biology. PMID 27474396 DOI: 10.1016/J.Ydbio.2016.07.019  1
2016 Cox AG, Hwang KL, Brown KK, Evason KJ, Beltz S, Tsomides A, O'Connor K, Galli GG, Yimlamai D, Chhangawala S, Yuan M, Lien EC, Wucherpfennig J, Nissim S, Minami A, ... ... Goessling W, et al. Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature Cell Biology. PMID 27428308 DOI: 10.1038/Ncb3389  1
2016 Kwan W, Cortes M, Frost I, Esain V, Theodore LN, Liu SY, Budrow N, Goessling W, North TE. The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell. PMID 27424782 DOI: 10.1016/J.Stem.2016.06.004  1
2016 Walesky C, Goessling W. Nature and Nurture - Environmental Toxins and Biliary Atresia. Hepatology (Baltimore, Md.). PMID 27349921 DOI: 10.1002/Hep.28701  1
2016 Bao XR, Ong SE, Goldberger O, Peng J, Sharma R, Thompson DA, Vafai SB, Cox AG, Marutani E, Ichinose F, Goessling W, Regev A, Carr SA, Clish CB, Mootha VK. Mitochondrial dysfunction remodels one-carbon metabolism in human cells. Elife. 5. PMID 27307216 DOI: 10.7554/Elife.10575  1
2016 Hwang KL, Goessling W. Baiting for Cancer: Using the Zebrafish as a Model in Liver and Pancreatic Cancer. Advances in Experimental Medicine and Biology. 916: 391-410. PMID 27165363 DOI: 10.1007/978-3-319-30654-4_17  0.01
2016 Goessling W, North TE. EnaBILEing Growth in the Fetal Liver. Cell Stem Cell. 18: 427-8. PMID 27058931 DOI: 10.1016/J.Stem.2016.03.019  1
2016 Jain IH, Zazzeron L, Goli R, Alexa K, Schatzman-Bone S, Dhillon H, Goldberger O, Peng J, Shalem O, Sanjana NE, Zhang F, Goessling W, Zapol WM, Mootha VK. Hypoxia as a therapy for mitochondrial disease. Science (New York, N.Y.). PMID 26917594 DOI: 10.1126/Science.Aad9642  1
2016 Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW. Corrigendum: Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nature Cell Biology. 18: 347. PMID 26911913 DOI: 10.1038/Ncb3318  1
2016 Liu LY, Alexa K, Cortes M, Schatzman-Bone S, Kim AJ, Mukhopadhyay B, Cinar R, Kunos G, North TE, Goessling W. Cannabinoid receptor signaling regulates liver development and metabolism. Development (Cambridge, England). 143: 609-22. PMID 26884397 DOI: 10.1242/Dev.121731  1
2015 Mancias JD, Pontano Vaites L, Nissim S, Biancur DE, Kim AJ, Wang X, Liu Y, Goessling W, Kimmelman AC, Harper JW. Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. Elife. 4. PMID 26436293 DOI: 10.7554/Elife.10308  1
2015 Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW. Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nature Cell Biology. PMID 26389662 DOI: 10.1038/Ncb3238  1
2015 Cortes M, Liu SY, Kwan W, Alexa K, Goessling W, North TE. Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation. Stem Cell Reports. 5: 471-9. PMID 26365513 DOI: 10.1016/J.Stemcr.2015.08.010  1
2015 Goessling W, Sadler KC. Zebrafish: An Important Tool for Liver Disease Research. Gastroenterology. 149: 1361-77. PMID 26319012 DOI: 10.1053/J.Gastro.2015.08.034  1
2015 Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. Stem Cells (Dayton, Ohio). PMID 25931248 DOI: 10.1002/Stem.2044  1
2015 Cox AG, Goessling W. The lure of zebrafish in liver research: regulation of hepatic growth in development and regeneration. Current Opinion in Genetics & Development. 32: 153-61. PMID 25863341 DOI: 10.1016/J.Gde.2015.03.002  1
2015 Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, et al. ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Nature Communications. 6: 6023. PMID 25599650 DOI: 10.1038/Ncomms7023  1
2015 Bao XR, Ong S, Goldberger O, Peng J, Sharma R, Thompson DA, Vafai SB, Cox AG, Marutani E, Ichinose F, Goessling W, Regev A, Carr SA, Clish CB, Mootha VK. Author response: Mitochondrial dysfunction remodels one-carbon metabolism in human cells Elife. DOI: 10.7554/Elife.10575.030  1
2015 Mancias JD, Vaites LP, Nissim S, Biancur DE, Kim AJ, Wang X, Liu Y, Goessling W, Kimmelman AC, Harper JW. Author response: Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis Elife. DOI: 10.7554/Elife.10308.014  1
2015 Kwan W, Cortes M, Liu S, Frost I, Goessling W, North T. Hypoxic Stress-Induced Serotonergic Stimulation Controls Hematopoietic Stem Cell Production Via the Hypothalamic-Pituitary-Interrenal Axis and Glucocorticoid Signaling Blood. 126: 895-895. DOI: 10.1182/Blood.V126.23.895.895  1
2015 Cox AG, Hwang KL, Evason K, Brown KK, Beltz S, O'Connor K, Galli GG, Yimlamai D, Chhangawala S, Lien E, Camargo FD, Asara J, Houvras Y, Stainier DY, Goessling W. Abstract 5151: Yap reprograms glutamine metabolism and supports growth during liver development and tumorigenesis Cancer Research. 75: 5151-5151. DOI: 10.1158/1538-7445.Am2015-5151  1
2015 Nissim S, Weeks O, Hedgepeth J, Wucherpfennig J, Wang X, Kimmelman A, Goessling W. Abstract 5148: NR5A2 is essential for pancreas development and affects pancreas carcinogenesis Cancer Research. 75: 5148-5148. DOI: 10.1158/1538-7445.Am2015-5148  1
2015 Cox AG, Goessling W. The lure of zebrafish in liver research: Regulation of hepatic growth in development and regeneration Current Opinion in Genetics and Development. 32: 153-161. DOI: 10.1016/j.gde.2015.03.002  1
2015 Kwan W, Cortes M, Liu SY, Goessling W, North TE. Serotonin regulates HSC formation via glucocorticoid production from the hypothalamic-pituitary-interrenal axis Experimental Hematology. 43. DOI: 10.1016/J.Exphem.2015.06.053  1
2014 Goessling W, North TE. Repairing quite swimmingly: advances in regenerative medicine using zebrafish. Disease Models & Mechanisms. 7: 769-76. PMID 24973747 DOI: 10.1242/Dev.114751  1
2014 McMahon GM, Olden M, Garnaas M, Yang Q, Liu X, Hwang SJ, Larson MG, Goessling W, Fox CS. Sequencing of LRP2 reveals multiple rare variants associated with urinary trefoil factor-3. Journal of the American Society of Nephrology : Jasn. 25: 2896-905. PMID 24876117 DOI: 10.1681/Asn.2013111240  1
2014 Carroll KJ, Esain V, Garnaas MK, Cortes M, Dovey MC, Nissim S, Frechette GM, Liu SY, Kwan W, Cutting CC, Harris JM, Gorelick DA, Halpern ME, Lawson ND, Goessling W, et al. Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche. Developmental Cell. 29: 437-53. PMID 24871948 DOI: 10.1016/J.Devcel.2014.04.012  1
2014 Cox AG, Goessling W. Regenerative biology: Take the brakes off for liver repair. Nature. 506: 299-300. PMID 24553235 DOI: 10.1038/506299A  1
2014 Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Developmental Cell. 28: 423-37. PMID 24530296 DOI: 10.1016/J.Devcel.2014.01.006  1
2014 Cox AG, Saunders DC, Kelsey PB, Conway AA, Tesmenitsky Y, Marchini JF, Brown KK, Stamler JS, Colagiovanni DB, Rosenthal GJ, Croce KJ, North TE, Goessling W. S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury Cell Reports. 6: 56-69. PMID 24388745 DOI: 10.1016/J.Celrep.2013.12.007  1
2014 Nissim S, Wucherpfennig J, Wang X, Kimmelman A, Goessling W. Abstract 1953: The role of NR5a2 in pancreas development and carcinogenesis Cancer Research. 74: 1953-1953. DOI: 10.1158/1538-7445.Am2014-1953  1
2014 Kwan W, Cortes M, Goessling W, North T. Serotonergic regulation of hematopoietic stem cell production in the AGM Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.161  1
2013 Ryan S, Willer J, Marjoram L, Bagwell J, Mankiewicz J, Leshchiner I, Goessling W, Bagnat M, Katsanis N. Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish. Development (Cambridge, England). 140: 4445-51. PMID 24130329 DOI: 10.1242/Dev.101170  1
2013 Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, ... ... Goessling W, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 122: 3074-81. PMID 23996087 DOI: 10.1182/Blood-2013-05-503177  1
2013 Liu LY, Fox CS, North TE, Goessling W. Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development. Disease Models & Mechanisms. 6: 1271-8. PMID 23813869 DOI: 10.1242/Dmm.011726  1
2013 Shan J, Schwartz RE, Ross NT, Logan DJ, Thomas D, Duncan SA, North TE, Goessling W, Carpenter AE, Bhatia SN. Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nature Chemical Biology. 9: 514-20. PMID 23728495 DOI: 10.1038/Nchembio.1270  1
2013 Wolpin BM, Ng K, Zhu AX, Abrams T, Enzinger PC, McCleary NJ, Schrag D, Kwak EL, Allen JN, Bhargava P, Chan JA, Goessling W, Blaszkowsky LS, Supko JG, Elliot M, et al. Multicenter phase II study of tivozanib (AV-951) and everolimus (RAD001) for patients with refractory, metastatic colorectal cancer. The Oncologist. 18: 377-8. PMID 23580238 DOI: 10.1634/Theoncologist.2012-0378  1
2013 Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, ... ... Goessling W, et al. Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo. Blood. 121: 2483-93. PMID 23341543 DOI: 10.1182/Blood-2012-12-471201  1
2013 Kwak EL, Goyal L, Abrams TA, Carpenter A, Wolpin BM, Wadlow RC, Allen JN, Heist RS, McCleary NJ, Chan JA, Goessling W, Schrag D, Evans C, Ng K, Enzinger PC, et al. A phase II clinical trial of ganetespib (STA-9090) in previously treated patients with advanced esophagogastric cancers. Journal of Clinical Oncology. 31: 4090-4090. DOI: 10.1200/Jco.2013.31.15_Suppl.4090  1
2013 Nissim S, Wucherpfennig J, Wang X, Kimmelman A, Goessling W. Abstract 2657: The role of NR5A2 in pancreas development and oncogenesis. Cancer Research. 73: 2657-2657. DOI: 10.1158/1538-7445.Am2013-2657  1
2013 Cox AG, Beltz S, Evason K, Stainier DY, North TE, Goessling W. Abstract 1574: The Hippo pathway regulates liver development and tumorigenesis in zebrafish. Cancer Research. 73: 1574-1574. DOI: 10.1158/1538-7445.Am2013-1574  1
2013 Cohen AR, Cox AG, Goessling W. Tu2049 Hydrogen Sulfide (H2S) Regulates Liver Development and Protects From Acetaminophen (APAP)-Induced Liver Injury in Zebrafish Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63405-8  1
2013 Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, ... ... Goessling W, et al. Erratum: β-catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis (Cell (2012) 151 (1457-1473)) Cell. 153: 267-270. DOI: 10.1016/J.Cell.2013.03.007  1
2012 Wolpin BM, Ng K, Zhu AX, Abrams TA, Enzinger PC, McCleary N, Meyerhardt JA, Schrag D, Kwak EL, Allen JN, Bhargava P, Chan JA, Goessling W, Blaszkowsky LS, Elliott M, et al. Multicenter phase Ib/II study of everolimus (RAD001) and tivozanib (AV-951) in patients with refractory, metastatic colorectal cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 560. PMID 27983189 DOI: 10.1200/Jco.2012.30.4_Suppl.560  1
2012 Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, ... ... Goessling W, et al. β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell. 151: 1457-73. PMID 23245941 DOI: 10.1016/J.Cell.2012.11.026  1
2012 Garnaas MK, Cutting CC, Meyers A, Kelsey PB, Harris JM, North TE, Goessling W. Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Developmental Biology. 372: 178-89. PMID 22982668 DOI: 10.1016/J.Ydbio.2012.09.001  1
2012 Goessling W. Hepatic stellate cells and cirrhosis: fishing for cures. Hepatology (Baltimore, Md.). 56: 1596-8. PMID 22821548 DOI: 10.1002/Hep.25981  0.01
2012 Shaik S, Nucera C, Inuzuka H, Gao D, Garnaas M, Frechette G, Harris L, Wan L, Fukushima H, Husain A, Nose V, Fadda G, Sadow PM, Goessling W, North T, et al. SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. The Journal of Experimental Medicine. 209: 1289-307. PMID 22711876 DOI: 10.1084/Jem.20112446  1
2012 Leshchiner I, Alexa K, Kelsey P, Adzhubei I, Austin-Tse CA, Cooney JD, Anderson H, King MJ, Stottmann RW, Garnaas MK, Ha S, Drummond IA, Paw BH, North TE, Beier DR, ... Goessling W, et al. Mutation mapping and identification by whole-genome sequencing. Genome Research. 22: 1541-8. PMID 22555591 DOI: 10.1101/Gr.135541.111  1
2012 Cortes M, Natsuhara K, Goessling W, North TE. Vitamin D3 Modulates Definitive Hematopoiesis by Two Distinct Mechanisms in the Developing Zebrafish Embryo Blood. 120: 763-763. DOI: 10.1182/Blood.V120.21.763.763  1
2011 Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, ... ... Goessling W, et al. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nature Genetics. 43: 1131-8. PMID 22001757 DOI: 10.1038/Ng.970  1
2011 Goessling W, North TE. Hematopoietic stem cell development: using the zebrafish to identify the signaling networks and physical forces regulating hematopoiesis. Methods in Cell Biology. 105: 117-36. PMID 21951528 DOI: 10.1016/B978-0-12-381320-6.00005-9  1
2011 Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, Peralta CA, de Boer IH, Lu X, Atkinson E, Ding J, Nalls M, Shriner D, Coresh J, Kutlar A, Bibbins-Domingo K, ... ... Goessling W, et al. Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. Plos Genetics. 7: e1002264. PMID 21931561 DOI: 10.1371/Journal.Pgen.1002264  1
2011 Saadi I, Alkuraya FS, Gisselbrecht SS, Goessling W, Cavallesco R, Turbe-Doan A, Petrin AL, Harris J, Siddiqui U, Grix AW, Hove HD, Leboulch P, Glover TW, Morton CC, Richieri-Costa A, et al. Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting. American Journal of Human Genetics. 89: 44-55. PMID 21703590 DOI: 10.1016/J.Ajhg.2011.05.023  1
2011 North TE, Goessling W. Endoderm specification, liver development, and regeneration. Methods in Cell Biology. 101: 205-23. PMID 21550446 DOI: 10.1016/B978-0-12-387036-0.00010-4  1
2011 Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, et al. Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell. 8: 445-58. PMID 21474107 DOI: 10.1016/J.Stem.2011.02.003  1
2010 North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W. PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proceedings of the National Academy of Sciences of the United States of America. 107: 17315-20. PMID 20855591 DOI: 10.1073/Pnas.1008209107  1
2010 Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA. The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (New York, N.Y.). 327: 1650-3. PMID 20339075 DOI: 10.1126/Science.1186624  1
2010 North TE, Goessling W. Previews. NOTCHing an arrow at cord blood: translating stem cell knowledge into clinical practice. Cell Stem Cell. 6: 186-7. PMID 20207217 DOI: 10.1016/J.Stem.2010.02.009  1
2010 Baba Y, Nosho K, Shima K, Goessling W, Chan AT, Ng K, Chan JA, Giovannucci EL, Fuchs CS, Ogino S. PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 822-31. PMID 20200425 DOI: 10.1158/1055-9965.Epi-09-1154  1
2009 Goessling W. Deciphering hepatocellular carcinoma: from bench to bedside and back. Gastroenterology. 137: 786-8. PMID 19643190 DOI: 10.1053/J.Gastro.2009.07.033  0.01
2009 North TE, Goessling W, Peeters M, Li P, Ceol C, Lord AM, Weber GJ, Harris J, Cutting CC, Huang P, Dzierzak E, Zon LI. Hematopoietic stem cell development is dependent on blood flow. Cell. 137: 736-48. PMID 19450519 DOI: 10.1016/J.Cell.2009.04.023  1
2009 Dovey M, Patton EE, Bowman T, North T, Goessling W, Zhou Y, Zon LI. Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish. Molecular and Cellular Biology. 29: 3746-53. PMID 19380487 DOI: 10.1128/Mcb.01684-08  1
2009 Goessling W, North TE, Loewer S, Lord AM, Lee S, Stoick-Cooper CL, Weidinger G, Puder M, Daley GQ, Moon RT, Zon LI. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell. 136: 1136-47. PMID 19303855 DOI: 10.1016/J.Cell.2009.01.015  1
2008 Goessling W, Massaro JM, Vasan RS, D'Agostino RB, Ellison RC, Fox CS. Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease. Gastroenterology. 135: 1935-44, 1944.e1. PMID 19010326 DOI: 10.1053/J.Gastro.2008.09.018  1
2008 Upadhyay G, Goessling W, North TE, Xavier R, Zon LI, Yajnik V. Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling. Oncogene. 27: 5845-55. PMID 18641688 DOI: 10.1038/Onc.2008.202  1
2008 Goessling W, North TE, Lord AM, Ceol C, Lee S, Weidinger G, Bourque C, Strijbosch R, Haramis AP, Puder M, Clevers H, Moon RT, Zon LI. APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Developmental Biology. 320: 161-74. PMID 18585699 DOI: 10.1016/J.Ydbio.2008.05.526  1
2008 White RM, Sessa A, Burke C, Bowman T, LeBlanc J, Ceol C, Bourque C, Dovey M, Goessling W, Burns CE, Zon LI. Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell. 2: 183-9. PMID 18371439 DOI: 10.1016/J.Stem.2007.11.002  1
2007 North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature. 447: 1007-11. PMID 17581586 DOI: 10.1038/Nature05883  1
2007 Goessling W, North TE, Zon LI. Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors. Nature Methods. 4: 551-3. PMID 17572681 DOI: 10.1038/Nmeth1059  1
2007 Goessling W, North TE, Zon LI. New waves of discovery: modeling cancer in zebrafish. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 25: 2473-9. PMID 17557959 DOI: 10.1200/Jco.2006.08.9821  1
2007 Langenau DM, Keefe MD, Storer NY, Guyon JR, Kutok JL, Le X, Goessling W, Neuberg DS, Kunkel LM, Zon LI. Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes & Development. 21: 1382-95. PMID 17510286 DOI: 10.1101/Gad.1545007  1
2006 Goessling W, Mayer RJ. Systemic treatment of patients who have colorectal cancer and inflammatory bowel disease. Gastroenterology Clinics of North America. 35: 713-27. PMID 16952747 DOI: 10.1016/J.Gtc.2006.07.006  1
2005 Goessling W, Friedman LS. Increased liver chemistry in an asymptomatic patient. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 3: 852-8. PMID 16234021 DOI: 10.1016/S1542-3565(05)00416-7  0.01
2002 Goessling W, Chung RT. Amebic Liver Abscess. Current Treatment Options in Gastroenterology. 5: 443-449. PMID 12408781  0.01
2002 Goessling W, McKee PH, Mayer RJ. Merkel cell carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 588-98. PMID 11786590 DOI: 10.1200/Jco.20.2.588  1
2000 Goessling W, Zucker SD. Role of apolipoprotein D in the transport of bilirubin in plasma. American Journal of Physiology-Gastrointestinal and Liver Physiology. 279. PMID 10915645 DOI: 10.1152/Ajpgi.2000.279.2.G356  1
2000 Zucker SD, Goessling W. Mechanism of hepatocellular uptake of albumin-bound bilirubin. Biochimica Et Biophysica Acta. 1463: 197-208. PMID 10675499 DOI: 10.1016/S0005-2736(99)00196-0  1
1999 Zucker SD, Goessling W, Hoppin AG. Unconjugated Bilirubin Exhibits Spontaneous Diffusion through Model Lipid Bilayers and Native Hepatocyte Membranes Journal of Biological Chemistry. 274: 10852-10862. PMID 10196162 DOI: 10.1074/Jbc.274.16.10852  1
1996 Zucker SD, Goessling W, Gollan JL. Intracellular transport of small hydrophobic compounds by the hepatocyte Seminars in Liver Disease. 16: 159-167. PMID 8781021 DOI: 10.1055/S-2007-1007229  1
1995 Zucker SD, Goessling W, Gollan JL. Kinetics of bilirubin transfer between serum albumin and membrane vesicles: Insight into the mechanism of organic anion delivery to the hepatocyte plasma membrane Journal of Biological Chemistry. 270: 1074-1081. PMID 7836362 DOI: 10.1074/Jbc.270.3.1074  1
1995 Zucker SD, Goessling W, Ransil BJ, Gollan JL. Influence of glutathione S-transferase B (ligandin) on the intermembrane transfer of bilirubin: Implications for the intracellular transport of nonsubstrate ligands in hepatocytes Journal of Clinical Investigation. 96: 1927-1935. PMID 7560084 DOI: 10.1172/Jci118238  1
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