Jianfu Chen, Ph.D. - Publications

Affiliations: 
2008 Cell & Developmental Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cell Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhang W, Ma L, Yang M, Shao Q, Xu J, Lu Z, Zhao Z, Chen R, Chai Y, Chen JF. Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Genes & Development. PMID 32115408 DOI: 10.1101/Gad.332494.119  0.6
2020 Liang C, Shao Q, Zhang W, Yang M, Chang Q, Chen R, Chen JF. Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models. Human Molecular Genetics. PMID 32057072 DOI: 10.1093/hmg/ddaa012  0.458
2019 Shao Q, Yang M, Liang C, Ma L, Zhang W, Jiang Z, Luo J, Lee JK, Liang C, Chen JF. and mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis. Autophagy. PMID 31847700 DOI: 10.1080/15548627.2019.1703353  0.583
2019 Liang C, Shao Q, Zhang W, Yang M, Chang Q, Chen R, Chen JF. Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models. Human Molecular Genetics. PMID 31625563 DOI: 10.1093/Hmg/Ddz230  0.552
2019 Zhang W, Yang SL, Yang M, Herrlinger S, Shao Q, Collar JL, Fierro E, Shi Y, Liu A, Lu H, Herring BE, Guo ML, Buch S, Zhao Z, Xu J, ... ... Chen JF, et al. Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors. Nature Communications. 10: 2612. PMID 31197141 DOI: 10.1038/S41467-019-10497-2  0.784
2019 Herrlinger S, Shao Q, Yang M, Chang Q, Liu Y, Pan X, Yin H, Xie LW, Chen JF. Lin28-mediated promotion of protein synthesis is critical for neural progenitor cell maintenance and brain development in mice. Development (Cambridge, England). PMID 31064784 DOI: 10.1242/Dev.173765  0.783
2019 Gao F, Kataoka M, Liu N, Liang T, Huang ZP, Gu F, Ding J, Liu J, Zhang F, Ma Q, Wang Y, Zhang M, Hu X, Kyselovic J, Hu X, ... ... Chen J, et al. Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction. Nature Communications. 10: 1802. PMID 30996254 DOI: 10.1038/S41467-019-09530-1  0.548
2019 Shao Q, Liang C, Chang Q, Zhang W, Yang M, Chen JF. C9orf72 deficiency promotes motor deficits of a C9ALS/FTD mouse model in a dose-dependent manner. Acta Neuropathologica Communications. 7: 32. PMID 30832726 DOI: 10.1186/S40478-019-0685-7  0.52
2018 Herrlinger SA, Shao Q, Ma L, Brindley M, Chen JF. Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult. Journal of Visualized Experiments : Jove. PMID 29757270 DOI: 10.3791/56486  0.762
2018 Dong K, Guo X, Chen W, Hsu AC, Shao Q, Chen JF, Chen SY. Mesenchyme Homeobox 1 mediates transforming growth factor-β (TGF-β)-induced smooth muscle cell differentiation from mouse mesenchymal progenitors. The Journal of Biological Chemistry. PMID 29678882 DOI: 10.1074/Jbc.Ra118.002350  0.582
2018 Wang YC, Chuang YH, Shao Q, Chen JF, Chen SY. Brain cytoplasmic RNA 1 suppresses smooth muscle differentiation and vascular development in mice. The Journal of Biological Chemistry. PMID 29467228 DOI: 10.1074/Jbc.Ra117.001578  0.608
2017 Diniz GP, Huang ZP, Liu J, Chen J, Ding J, Fonseca RI, Barreto-Chaves ML, Donato J, Hu X, Wang DZ. Loss of microRNA-22 prevents high fat diet induced dyslipidemia and increases energy expenditure without affecting cardiac hypertrophy. Clinical Science (London, England : 1979). PMID 29101298 DOI: 10.1042/Cs20171368  0.56
2017 Shao Q, Herrlinger S, Zhu YN, Yang M, Goodfellow F, Stice SL, Qi XP, Brindley MA, Chen JF. The African Zika virus MR-766 is more virulent and causes more severe brain damage than current Asian lineage and Dengue virus. Development (Cambridge, England). PMID 28993398 DOI: 10.1242/Dev.156752  0.759
2017 Ai S, Peng Y, Li C, Gu F, Yu X, Yue Y, Ma Q, Chen J, Lin Z, Zhou P, Xie H, Prendiville TW, Zheng W, Liu Y, Orkin SH, et al. EED orchestration of heart maturation through interaction with HDACs is H3K27me3-independent. Elife. 6. PMID 28394251 DOI: 10.7554/Elife.24570  0.547
2016 Shao Q, Herrlinger S, Yang SL, Lai F, Moore JM, Brindley MA, Chen JF. Zika virus infection disrupts neurovascular development and results in postnatal microcephaly with brain damage. Development (Cambridge, England). PMID 27729407 DOI: 10.1242/Dev.143768  0.763
2016 Yang M, Liang C, Swaminathan K, Herrlinger S, Lai F, Shiekhattar R, Chen JF. A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy. Science Advances. 2: e1601167. PMID 27617292 DOI: 10.1126/Sciadv.1601167  0.771
2016 Huang ZP, Ding Y, Chen J, Wu G, Kataoka M, Hu Y, Yang JH, Liu J, Drakos SG, Selzman CH, Kyselovic J, Qu LH, Dos Remedios CG, Pu WT, Wang DZ. Long non-coding RNAs link extracellular matrix gene expression to ischemic cardiomyopathy. Cardiovascular Research. PMID 27557636 DOI: 10.1093/cvr/cvw201  0.515
2015 Yang SL, Yang M, Herrlinger S, Liang C, Lai F, Chen JF. MiR-302/367 regulate neural progenitor proliferation, differentiation, and survival in neurulation. Developmental Biology. PMID 26441343 DOI: 10.1016/J.Ydbio.2015.09.020  0.797
2015 Huang ZP, Kataoka M, Chen J, Wu G, Ding J, Nie M, Lin Z, Liu J, Hu X, Ma L, Zhou B, Wakimoto H, Zeng C, Kyselovic J, Deng ZL, et al. Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. The Journal of Clinical Investigation. PMID 26436652 DOI: 10.1172/Jci82423  0.566
2015 Ding J, Chen J, Wang Y, Kataoka M, Ma L, Zhou P, Hu X, Lin Z, Nie M, Deng ZL, Pu WT, Wang DZ. Trbp regulates heart function through microRNA-mediated Sox6 repression. Nature Genetics. 47: 776-83. PMID 26029872 DOI: 10.1038/Ng.3324  0.618
2015 Prendiville TW, Guo H, Lin Z, Zhou P, Stevens SM, He A, VanDusen N, Chen J, Zhong L, Wang DZ, Gao G, Pu WT. Novel Roles of GATA4/6 in the Postnatal Heart Identified through Temporally Controlled, Cardiomyocyte-Specific Gene Inactivation by Adeno-Associated Virus Delivery of Cre Recombinase. Plos One. 10: e0128105. PMID 26023924 DOI: 10.1371/Journal.Pone.0128105  0.558
2015 Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF. Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development (Cambridge, England). 142: 1616-27. PMID 25922525 DOI: 10.1242/Dev.120543  0.792
2015 Wang G, Chen JH, Qiang Y, Wang DZ, Chen Z. Decreased STAT4 indicates poor prognosis and enhanced cell proliferation in hepatocellular carcinoma. World Journal of Gastroenterology : Wjg. 21: 3983-93. PMID 25852285 DOI: 10.3748/wjg.v21.i13.3983  0.446
2015 Lin Z, Zhou P, von Gise A, Gu F, Ma Q, Chen J, Guo H, van Gorp PR, Wang DZ, Pu WT. Pi3kcb links Hippo-YAP and PI3K-AKT signaling pathways to promote cardiomyocyte proliferation and survival. Circulation Research. 116: 35-45. PMID 25249570 DOI: 10.1161/Circresaha.115.304457  0.496
2014 Wu G, Cai J, Han Y, Chen J, Huang ZP, Chen C, Cai Y, Huang H, Yang Y, Liu Y, Xu Z, He D, Zhang X, Hu X, Pinello L, et al. LincRNA-p21 regulates neointima formation, vascular smooth muscle cell proliferation, apoptosis, and atherosclerosis by enhancing p53 activity. Circulation. 130: 1452-65. PMID 25156994 DOI: 10.1161/Circulationaha.114.011675  0.488
2014 Chen JF, Zhang Y, Wilde J, Hansen KC, Lai F, Niswander L. Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nature Communications. 5: 3885. PMID 24875059 DOI: 10.1038/Ncomms4885  0.633
2014 Lin Z, von Gise A, Zhou P, Gu F, Ma Q, Jiang J, Yau AL, Buck JN, Gouin KA, van Gorp PR, Zhou B, Chen J, Seidman JG, Wang DZ, Pu WT. Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model. Circulation Research. 115: 354-63. PMID 24833660 DOI: 10.1161/Circresaha.115.303632  0.549
2014 Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zhang D, Zangi L, Geva J, Roberts AE, Ma Q, Ding J, Chen J, et al. Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. Nature Medicine. 20: 616-23. PMID 24813252 DOI: 10.1038/Nm.3545  0.498
2014 Seok HY, Chen J, Kataoka M, Huang ZP, Ding J, Yan J, Hu X, Wang DZ. Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophy. Circulation Research. 114: 1585-95. PMID 24657879 DOI: 10.1161/Circresaha.114.303784  0.746
2014 Harmacek L, Watkins-Chow DE, Chen J, Jones KL, Pavan WJ, Salbaum JM, Niswander L. A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice. Developmental Neurobiology. 74: 483-97. PMID 24170322 DOI: 10.1002/Dneu.22142  0.778
2013 Chen J, Huang ZP, Seok HY, Ding J, Kataoka M, Zhang Z, Hu X, Wang G, Lin Z, Wang S, Pu WT, Liao R, Wang DZ. mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circulation Research. 112: 1557-66. PMID 23575307 DOI: 10.1161/Circresaha.112.300658  0.754
2013 Huang ZP, Chen J, Seok HY, Zhang Z, Kataoka M, Hu X, Wang DZ. MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circulation Research. 112: 1234-43. PMID 23524588 DOI: 10.1161/Circresaha.112.300682  0.747
2012 Chen J, Lai F, Niswander L. The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes & Development. 26: 803-15. PMID 22508726 DOI: 10.1101/Gad.187641.112  0.607
2012 Huang ZP, Young Seok H, Zhou B, Chen J, Chen JF, Tao Y, Pu WT, Wang DZ. CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circulation Research. 110: 818-30. PMID 22343712 DOI: 10.1161/Circresaha.111.259663  0.578
2012 Chen J, Wang DZ. microRNAs in cardiovascular development. Journal of Molecular and Cellular Cardiology. 52: 949-57. PMID 22300733 DOI: 10.1016/J.Yjmcc.2012.01.012  0.588
2011 Tao Y, Neppl RL, Huang ZP, Chen J, Tang RH, Cao R, Zhang Y, Jin SW, Wang DZ. The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly. The Journal of Cell Biology. 194: 551-65. PMID 21859860 DOI: 10.1083/Jcb.201010090  0.558
2011 Deng Z, Chen JF, Wang DZ. Transgenic overexpression of miR-133a in skeletal muscle. Bmc Musculoskeletal Disorders. 12: 115. PMID 21615921 DOI: 10.1186/1471-2474-12-115  0.641
2011 Chen J, Yin H, Jiang Y, Radhakrishnan SK, Huang ZP, Li J, Shi Z, Kilsdonk EP, Gui Y, Wang DZ, Zheng XL. Induction of microRNA-1 by myocardin in smooth muscle cells inhibits cell proliferation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 368-75. PMID 21051663 DOI: 10.1161/Atvbaha.110.218149  0.578
2010 Huang ZP, Chen JF, Regan JN, Maguire CT, Tang RH, Dong XR, Majesky MW, Wang DZ. Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 2575-86. PMID 20884876 DOI: 10.1161/Atvbaha.110.213306  0.606
2010 Chen JF, Tao Y, Li J, Deng Z, Yan Z, Xiao X, Wang DZ. microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. The Journal of Cell Biology. 190: 867-79. PMID 20819939 DOI: 10.1083/Jcb.200911036  0.563
2009 Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, Willis MS, Selzman CH, Wang DZ. MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. The Journal of Clinical Investigation. 119: 2772-86. PMID 19726871 DOI: 10.1172/Jci36154  0.796
2009 Chen JF, Callis TE, Wang DZ. microRNAs and muscle disorders. Journal of Cell Science. 122: 13-20. PMID 19092056 DOI: 10.1242/Jcs.041723  0.781
2008 Chen JF, Wang S, Wu Q, Cao D, Nguyen T, Chen Y, Wang DZ. Myocardin marks the earliest cardiac gene expression and plays an important role in heart development. Anatomical Record (Hoboken, N.J. : 2007). 291: 1200-11. PMID 18780304 DOI: 10.1002/Ar.20756  0.619
2008 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ. Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proceedings of the National Academy of Sciences of the United States of America. 105: 2111-6. PMID 18256189 DOI: 10.1073/Pnas.0710228105  0.774
2008 Callis TE, Deng Z, Chen JF, Wang DZ. Muscling through the microRNA world. Experimental Biology and Medicine (Maywood, N.J.). 233: 131-8. PMID 18222968 DOI: 10.3181/0709-Mr-237  0.783
2007 Gustafson-Wagner EA, Sinn HW, Chen YL, Wang DZ, Reiter RS, Lin JL, Yang B, Williamson RA, Chen J, Lin CI, Lin JJ. Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2680-92. PMID 17766470 DOI: 10.1152/Ajpheart.00806.2007  0.683
2007 Tatsuguchi M, Seok HY, Callis TE, Thomson JM, Chen JF, Newman M, Rojas M, Hammond SM, Wang DZ. Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy Journal of Molecular and Cellular Cardiology. 42: 1137-1141. PMID 17498736 DOI: 10.1016/J.Yjmcc.2007.04.004  0.794
2007 Callis TE, Chen JF, Wang DZ. MicroRNAs in skeletal and cardiac muscle development. Dna and Cell Biology. 26: 219-25. PMID 17465888 DOI: 10.1089/Dna.2006.0556  0.781
2007 Yan KL, Huang W, Zhang XJ, Yang S, Chen YM, Xiao FL, Fan X, Gao M, Cui Y, Zhang GL, Sun LD, Wang PG, Chen JJ, Li W, Chen ZH, et al. Follow-up analysis of PSORS9 in 151 Chinese families confirmed the linkage to 4q31-32 and refined the evidence to the families of early-onset psoriasis. The Journal of Investigative Dermatology. 127: 312-8. PMID 17139270 DOI: 10.1038/Sj.Jid.5700506  0.416
2006 Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM, Conlon FL, Wang DZ. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation Nature Genetics. 38: 228-233. PMID 16380711 DOI: 10.1038/Ng1725  0.785
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