Isabel E. Beerman, Ph.D. - Publications

Affiliations: 
2007 Yale University, New Haven, CT 
Area:
Genetics

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tanaka-Yano M, Zong L, Park B, Yanai H, Tekin-Turhan F, Blackshear PJ, Beerman I. Tristetraprolin overexpression drives hematopoietic changes in young and middle-aged mice generating dominant mitigating effects on induced inflammation in murine models. Geroscience. PMID 37535204 DOI: 10.1007/s11357-023-00879-2  0.787
2023 Schaffer ED, Beerman I, de Cabo R, Brosh RM. Frontiers in aging special issue: DNA repair and interventions in aging perspective on "loss of epigenetic information as a cause of mammalian aging". Frontiers in Aging. 4: 1199596. PMID 37475956 DOI: 10.3389/fragi.2023.1199596  0.383
2023 Stock AJ, Ayyar S, Kashyap A, Wang Y, Yanai H, Starost MF, Tanaka-Yano M, Bodogai M, Sun C, Wang Y, Gong Y, Puligilla C, Fang EF, Bohr VA, Liu Y, ... Beerman I, et al. Boosting NAD ameliorates hematopoietic impairment linked to short telomeres in vivo. Geroscience. PMID 36826621 DOI: 10.1007/s11357-023-00752-2  0.729
2022 Ayyar S, Beerman I. Detection of DNA Damage in Hematopoietic Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 2567: 11-28. PMID 36255692 DOI: 10.1007/978-1-0716-2679-5_2  0.331
2022 Chen C, Park B, Ragonnaud E, Bodogai M, Wang X, Zong L, Lee JM, Beerman I, Biragyn A. Cancer co-opts differentiation of B-cell precursors into macrophage-like cells. Nature Communications. 13: 5376. PMID 36104343 DOI: 10.1038/s41467-022-33117-y  0.741
2022 Yanai H, Dunn C, Park B, Coletta C, McDevitt RA, McNeely T, Leone M, Wersto RP, Perdue KA, Beerman I. Male rat leukocyte population dynamics predict a window for intervention in aging. Elife. 11. PMID 35507394 DOI: 10.7554/eLife.76808  0.728
2022 Tsitsipatis D, Martindale JL, Ubaida-Mohien C, Lyashkov A, Yanai H, Kashyap A, Shin CH, Herman AB, Ji E, Yang JH, Munk R, Dunn C, Lukyanenko Y, Yang X, Chia CW, ... ... Beerman I, et al. Proteomes of primary skin fibroblasts from healthy individuals reveal altered cell responses across the life span. Aging Cell. e13609. PMID 35429111 DOI: 10.1111/acel.13609  0.74
2022 Hare JM, Beerman I. Stem cells' potential to restore function in aging systems; are we there yet? The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 34984451 DOI: 10.1093/gerona/glac003  0.43
2021 Zong L, Tanaka-Yano M, Park B, Yanai H, Turhan FT, Croteau DL, Tian J, Fang EF, Bohr VA, Beerman I. NAD augmentation with nicotinamide riboside improves lymphoid potential of Atm and old mice HSCs. Npj Aging and Mechanisms of Disease. 7: 25. PMID 34548492 DOI: 10.1038/s41514-021-00078-3  0.8
2020 Yanai H, Beerman I. Proliferation: Driver of HSC aging phenotypes? Mechanisms of Ageing and Development. 191: 111331. PMID 32798509 DOI: 10.1016/J.Mad.2020.111331  0.81
2020 Spehar K, Pan A, Beerman I. Restoring Aged Stem Cell Functionality: Current Progress and Future Directions. Stem Cells (Dayton, Ohio). PMID 32473067 DOI: 10.1002/Stem.3234  0.554
2019 Luis TC, Wilkinson AC, Beerman I, Jaiswal S, Shlush LI. Biological implications of clonal hematopoiesis. Experimental Hematology. PMID 31472170 DOI: 10.1016/J.Exphem.2019.08.004  0.403
2019 McNeely T, Leone M, Yanai H, Beerman I. DNA damage in aging, the stem cell perspective. Human Genetics. PMID 31324975 DOI: 10.1007/S00439-019-02047-Z  0.786
2019 Hare JM, Beerman I. Regenerative Medicine and the Biology of Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 74: 1339-1340. PMID 31125054 DOI: 10.1093/Gerona/Glz132  0.426
2019 Beerman I. Loss of hematopoietic diversity with age. Blood. 133: 1921-1922. PMID 31048301 DOI: 10.1182/Blood-2019-03-900902  0.423
2019 Scaramozza A, Park D, Kollu S, Beerman I, Sun X, Rossi DJ, Lin CP, Scadden DT, Crist C, Brack AS. Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress. Cell Stem Cell. PMID 31006621 DOI: 10.1016/J.Stem.2019.03.020  0.671
2019 Elias HK, Shin JY, Ali MA, Chakraborty S, Ha CJ, Dolgalev I, Konishi C, Beerman I, Park CY. Identification of Old HSCs with Preserved Self-Renewal and Long-Term Reconstitution Potential Blood. 134: 2479-2479. DOI: 10.1182/Blood-2019-129508  0.386
2018 Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A. Targets and genomic constraints of ectopic Dnmt3b expression. Elife. 7. PMID 30468428 DOI: 10.7554/Elife.40757  0.622
2018 Beerman I. Cell umbrella protects stem cells from DNA damage. Nature. 558: 374-375. PMID 29907823 DOI: 10.1038/D41586-018-05166-1  0.483
2018 Beerman I. Set(d1a)-ing novel links between HSC regulators. Blood. 131: 1267-1269. PMID 29567754 DOI: 10.1182/Blood-2018-02-829077  0.488
2018 Gutierrez-Martinez P, Hogdal L, Nagai M, Kruta M, Singh R, Sarosiek K, Nussenzweig A, Beerman I, Letai A, Rossi DJ. Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage. Nature Cell Biology. PMID 29531308 DOI: 10.1038/S41556-018-0054-Y  0.72
2018 Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A. Author response: Targets and genomic constraints of ectopic Dnmt3b expression Elife. DOI: 10.7554/Elife.40757.024  0.553
2017 Garrison BS, Rybak AP, Beerman I, Heesters B, Mercier FE, Scadden DT, Bryder D, Baron R, Rossi DJ. ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells. Blood. PMID 28615219 DOI: 10.1182/Blood-2016-09-738591  0.79
2017 Beerman I, Luis TC, Singbrant S, Lo Celso C, Méndez-Ferrer S. The evolving view of the hematopoietic stem cell niche. Experimental Hematology. 50: 22-26. PMID 28189651 DOI: 10.1016/J.Exphem.2017.01.008  0.507
2017 Beerman I. Accumulation of DNA damage in the aged hematopoietic stem cell compartment. Seminars in Hematology. 54: 12-18. PMID 28088982 DOI: 10.1053/J.Seminhematol.2016.11.001  0.582
2016 Inoue S, Li WY, Tseng A, Beerman I, Elia AJ, Bendall SC, Lemonnier F, Kron KJ, Cescon DW, Hao Z, Lind EF, Takayama N, Planello AC, Shen SY, Shih AH, et al. Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2. Cancer Cell. PMID 27424808 DOI: 10.1016/J.Ccell.2016.05.018  0.66
2016 Gutierrez-Martinez P, Rossi DJ, Beerman I. DNA Damage and Aging Around the Clock. Trends in Molecular Medicine. 22: 635-637. PMID 27345866 DOI: 10.1016/J.Molmed.2016.06.006  0.706
2016 Kokkaliaris KD, Lucas D, Beerman I, Kent DG, Perié L. Understanding hematopoiesis from a single-cell standpoint. Experimental Hematology. 44: 447-50. PMID 26997547 DOI: 10.1016/J.Exphem.2016.03.003  0.445
2016 Thomas DD, Sommer AG, Balazs AB, Beerman I, Murphy GJ, Rossi D, Mostoslavsky G. Insulin-like growth factor 2 (IGF2) modulates murine hematopoietic stem cell maintenance through upregulation of p57. Experimental Hematology. PMID 26872540 DOI: 10.1016/J.Exphem.2016.01.010  0.668
2015 Beerman I, Rossi DJ. Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and Disease. Cell Stem Cell. 16: 613-25. PMID 26046761 DOI: 10.1016/J.Stem.2015.05.009  0.743
2015 Beerman I, Ziller M, Vandiver A, Gaudin R, Kirchhausen T, Feinberg A, Meissner A, Rossi D. AGE-associated clonal dominance of myeloid-biased HSC is underwritten by unique transcriptional and epigenetic alterations Experimental Hematology. 43: S49. DOI: 10.1016/J.Exphem.2015.06.065  0.68
2014 Stewart MH, Gutierrez-Martinez P, Beerman I, Garrison B, Gallagher EJ, LeRoith D, Rossi DJ. Growth hormone receptor signaling is dispensable for HSC function and aging. Blood. 124: 3076-80. PMID 25274507 DOI: 10.1182/Blood-2014-05-575308  0.8
2014 Beerman I, Rossi DJ. Epigenetic regulation of hematopoietic stem cell aging. Experimental Cell Research. 329: 192-9. PMID 25261778 DOI: 10.1016/J.Yexcr.2014.09.013  0.754
2014 Beerman I, Seita J, Inlay MA, Weissman IL, Rossi DJ. Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle. Cell Stem Cell. 15: 37-50. PMID 24813857 DOI: 10.1016/J.Stem.2014.04.016  0.753
2014 Beerman I, Seita J, Inlay M, Weissman I, Rossi D. Hematopoietic stem cell quiescence attenuates DNA damage repair and response contributing to age-dependent DNA damage accumulation Experimental Hematology. 42: S24. DOI: 10.1016/J.Exphem.2014.07.083  0.729
2013 Beerman I, Bock C, Garrison BS, Smith ZD, Gu H, Meissner A, Rossi DJ. Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. Cell Stem Cell. 12: 413-25. PMID 23415915 DOI: 10.1016/J.Stem.2013.01.017  0.736
2012 Bock C, Beerman I, Lien WH, Smith ZD, Gu H, Boyle P, Gnirke A, Fuchs E, Rossi DJ, Meissner A. DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Molecular Cell. 47: 633-47. PMID 22841485 DOI: 10.1016/J.Molcel.2012.06.019  0.683
2011 Pang WW, Price EA, Sahoo D, Beerman I, Maloney WJ, Rossi DJ, Schrier SL, Weissman IL. Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. Proceedings of the National Academy of Sciences of the United States of America. 108: 20012-7. PMID 22123971 DOI: 10.1073/Pnas.1116110108  0.757
2011 Gharavi AG, Kiryluk K, Choi M, Li Y, Hou P, Xie J, Sanna-Cherchi S, Men CJ, Julian BA, Wyatt RJ, Novak J, He JC, Wang H, Lv J, Zhu L, ... ... Beerman I, et al. Genome-wide association study identifies susceptibility loci for IgA nephropathy. Nature Genetics. 43: 321-7. PMID 21399633 DOI: 10.1038/Ng.787  0.559
2010 Beerman I, Maloney WJ, Weissmann IL, Rossi DJ. Stem cells and the aging hematopoietic system. Current Opinion in Immunology. 22: 500-6. PMID 20650622 DOI: 10.1016/J.Coi.2010.06.007  0.741
2010 Beerman I, Bhattacharya D, Zandi S, Sigvardsson M, Weissman IL, Bryder D, Rossi DJ. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proceedings of the National Academy of Sciences of the United States of America. 107: 5465-70. PMID 20304793 DOI: 10.1073/Pnas.1000834107  0.785
2006 Liu N, Beerman I, Lifton R, Zhao H. Haplotype analysis in the presence of informatively missing genotype data Genetic Epidemiology. 30: 290-300. PMID 16528706 DOI: 10.1002/Gepi.20144  0.443
2006 Izzi C, Sanna-Cherchi S, Prati E, Belleri R, Remedio A, Tardanico R, Foramitti M, Guerini S, Viola BF, Movilli E, Beerman I, Lifton R, Leone L, Gharavi A, Scolari F. Familial aggregation of primary glomerulonephritis in an Italian population isolate: Valtrompia study Kidney International. 69: 1033-1040. PMID 16528253 DOI: 10.1038/Sj.Ki.5000185  0.444
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