Derin B. Keskin, Ph.D. - Publications

Affiliations: 
2002 Medical College of Georgia, Augusta, GA, United States 
Area:
Immunology, Cell Biology

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bae J, Kitayama S, Herbert Z, Daheron L, Kurata K, Keskin D, Livak K, Li S, Tarannum M, Romee R, Samur MK, Munshi NC, Kaneko S, Ritz J, Anderson KC. Differentiation of BCMA-specific induced pluripotent stem cells into CD8αβ+ T cells targeting multiple myeloma. Blood. PMID 37890146 DOI: 10.1182/blood.2023020528  0.365
2023 Truex NL, Mohapatra S, Melo M, Rodriguez J, Li N, Abraham W, Sementa D, Touti F, Keskin DB, Wu CJ, Irvine DJ, Gómez-Bombarelli R, Pentelute BL. Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons. Biorxiv : the Preprint Server For Biology. PMID 37662211 DOI: 10.1101/2023.08.22.554289  0.328
2023 Mota I, Patrucco E, Mastini C, Mahadevan NR, Thai TC, Bergaggio E, Cheong TC, Leonardi G, Karaca-Atabay E, Campisi M, Poggio T, Menotti M, Ambrogio C, Longo DL, Klaeger S, ... ... Keskin DB, et al. ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer. Nature Cancer. PMID 37430060 DOI: 10.1038/s43018-023-00591-2  0.307
2022 Lee PC, Klaeger S, Le PM, Korthauer K, Cheng J, Ananthapadmanabhan V, Frost TC, Stevens JD, Wong AY, Iorgulescu JB, Tarren AY, Chea VA, Carulli IP, Lemvigh CK, Pedersen CB, ... ... Keskin DB, et al. Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma. The Journal of Clinical Investigation. 132. PMID 35775490 DOI: 10.1172/JCI151666  0.301
2022 Oliveira G, Stromhaug K, Cieri N, Iorgulescu JB, Klaeger S, Wolff JO, Rachimi S, Chea V, Krause K, Freeman SS, Zhang W, Li S, Braun DA, Neuberg D, Carr SA, ... ... Keskin DB, et al. Landscape of helper and regulatory antitumour CD4 T cells in melanoma. Nature. PMID 35508657 DOI: 10.1038/s41586-022-04682-5  0.34
2021 Bachireddy P, Azizi E, Burdziak C, Nguyen VN, Ennis CS, Maurer K, Park CY, Choo ZN, Li S, Gohil SH, Ruthen NG, Ge Z, Keskin DB, Cieri N, Livak KJ, et al. Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy. Cell Reports. 37: 109992. PMID 34758319 DOI: 10.1016/j.celrep.2021.109992  0.338
2021 Oliveira G, Stromhaug K, Klaeger S, Kula T, Frederick DT, Le PM, Forman J, Huang T, Li S, Zhang W, Xu Q, Cieri N, Clauser KR, Shukla SA, Neuberg D, ... ... Keskin DB, et al. Phenotype, specificity and avidity of antitumour CD8 T cells in melanoma. Nature. PMID 34290406 DOI: 10.1038/s41586-021-03704-y  0.371
2021 Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Gallagher KME, Bauer MR, Taylor HB, Dunn WA, Tarr C, Sidney J, Rachimi S, Conway HL, Katsis K, Wang Y, ... ... Keskin DB, et al. Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs. Cell. PMID 34171305 DOI: 10.1016/j.cell.2021.05.046  0.364
2021 Zhang G, Chitkushev L, Olsen LR, Keskin DB, Brusic V. TANTIGEN 2.0: a knowledge base of tumor T cell antigens and epitopes. Bmc Bioinformatics. 22: 40. PMID 33849445 DOI: 10.1186/s12859-021-03962-7  0.329
2021 Braun DA, Street K, Burke KP, Cookmeyer DL, Denize T, Pedersen CB, Gohil SH, Schindler N, Pomerance L, Hirsch L, Bakouny Z, Hou Y, Forman J, Huang T, Li S, ... ... Keskin DB, et al. Progressive immune dysfunction with advancing disease stage in renal cell carcinoma. Cancer Cell. PMID 33711273 DOI: 10.1016/j.ccell.2021.02.013  0.331
2021 Hu Z, Leet DE, Allesøe RL, Oliveira G, Li S, Luoma AM, Liu J, Forman J, Huang T, Iorgulescu JB, Holden R, Sarkizova S, Gohil SH, Redd RA, Sun J, ... ... Keskin DB, et al. Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma. Nature Medicine. PMID 33479501 DOI: 10.1038/s41591-020-01206-4  0.331
2021 Oliveira G, Stromhaug K, Klaeger S, Cieri N, Iorgulescu B, Li S, Braun D, Neuberg D, Carr S, Livak K, Tompers D, Fritsch E, Wind-Rotolo M, Hacohen N, Sade-Feldman M, ... Keskin D, et al. 655 Landscape of helper and regulatory CD4+ T cells in melanoma Journal For Immunotherapy of Cancer. 9: A684-A684. DOI: 10.1136/jitc-2021-sitc2021.655  0.348
2020 Kuai R, Singh PB, Sun X, Xu C, Najafabadi AH, Scheetz L, Yuan W, Xu Y, Hong H, Keskin DB, Wu CJ, Jain R, Schwendeman A, Moon JJ. Robust anti-tumor T cell response with efficient intratumoral infiltration by nanodisc cancer immunotherapy. Advanced Therapeutics. 3. PMID 38317797 DOI: 10.1002/adtp.202000094  0.323
2020 Sands RW, Tabansky I, Verbeke CS, Keskin D, Michel S, Stern J, Mooney DJ. Steroid-Peptide Immunoconjugates for Attenuating T Cell Responses in an Experimental Autoimmune Encephalomyelitis Murine Model of Multiple Sclerosis. Bioconjugate Chemistry. PMID 33284575 DOI: 10.1021/acs.bioconjchem.0c00582  0.333
2020 Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Bauer MR, Taylor HB, Conway HL, Tomkins-Tinch CH, Finkel Y, Nachshon A, Gentili M, Rivera KD, Keskin DB, Rice CM, et al. SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs. Biorxiv : the Preprint Server For Biology. PMID 33024965 DOI: 10.1101/2020.10.02.324145  0.333
2020 Bachireddy P, Ennis C, Nguyen VN, Gohil SH, Clement K, Shukla SA, Forman J, Barkas N, Freeman S, Bavli N, Elagina L, Leshchiner I, Mohammad AW, Mathewson ND, Keskin DB, et al. Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect. Science Translational Medicine. 12. PMID 32938797 DOI: 10.1126/Scitranslmed.Abb7661  0.354
2019 Sarkizova S, Klaeger S, Le PM, Li LW, Oliveira G, Keshishian H, Hartigan CR, Zhang W, Braun DA, Ligon KL, Bachireddy P, Zervantonakis IK, Rosenbluth JM, Ouspenskaia T, Law T, ... ... Keskin DB, et al. A large peptidome dataset improves HLA class I epitope prediction across most of the human population. Nature Biotechnology. PMID 31844290 DOI: 10.1038/S41587-019-0322-9  0.353
2019 Li S, Sun J, Allesøe R, Datta K, Bao Y, Oliveira G, Forman J, Jin R, Olsen LR, Keskin DB, Shukla SA, Wu CJ, Livak KJ. RNase H-dependent PCR-enabled T-cell receptor sequencing for highly specific and efficient targeted sequencing of T-cell receptor mRNA for single-cell and repertoire analysis. Nature Protocols. PMID 31341290 DOI: 10.1038/S41596-019-0195-X  0.378
2019 Sarkizova S, Klaeger S, Keskin DB, Clauser K, Keshishian H, Hartigan CR, Hacohen N, Carr SA, Wu CJ. Abstract B042: Broad analysis and more accurate predictions of HLA class I epitope binding in 92 common HLA alleles profiled by mono-allelic mass spectrometry Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B042  0.371
2019 Hu Z, Leet D, Sarkizova S, Holden R, Sun J, Klaeger S, Clauser KR, Shukla SA, Zhang W, Carr SA, Fritsch EF, Pentelute BL, Hacohen N, Keskin DB, Ott PA, et al. Abstract A010: Personalized neoantigen-targeting vaccines for high-risk melanoma generate epitope spreading Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A010  0.451
2019 Ouspenskaia T, Law TE, Clauser KR, Klaeger S, Keskin DB, Li B, Christian E, Chow YT, Le PM, Gould J, Ji Z, Zhang W, Bachireddy P, Sarkizova S, Hacohen N, et al. Abstract 566: Neoantigens from translated unannotated open reading frames in cancer Cancer Research. 79: 566-566. DOI: 10.1158/1538-7445.Am2019-566  0.39
2018 Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, et al. Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial. Nature. PMID 30568305 DOI: 10.1038/S41586-018-0792-9  0.444
2018 Hu Z, Anandappa AJ, Sun J, Kim J, Leet DE, Bozym DJ, Chen C, Williams L, Shukla SA, Zhang W, Tabbaa D, Steelman S, Olive O, Livak KJ, Kishi H, ... ... Keskin DB, et al. A cloning and expression system to probe T cell receptor specificity and assess functional avidity to neoantigens. Blood. PMID 30150207 DOI: 10.1182/Blood-2018-04-843763  0.463
2018 Tabansky I, Keskin DB, Watts D, Petzold C, Funaro M, Sands W, Wright P, Yunis EJ, Najjar S, Diamond B, Cao Y, Mooney D, Kretschmer K, Stern JNH. Targeting DEC-205DCIR2 dendritic cells promotes immunological tolerance in proteolipid protein-induced experimental autoimmune encephalomyelitis. Molecular Medicine (Cambridge, Mass.). 24: 17. PMID 30134798 DOI: 10.1186/S10020-018-0017-6  0.435
2018 Shukla SA, Bachireddy P, Schilling B, Galonska C, Zhan Q, Bango C, Langer R, Lee PC, Gusenleitner D, Keskin DB, Babadi M, Mohammad A, Gnirke A, Clement K, Cartun ZJ, et al. Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade. Cell. PMID 29656892 DOI: 10.1016/J.Cell.2018.03.026  0.323
2018 Reardon DA, Neuberg DS, Keskin DB, Tirosh I, Anandappa A, Mathewson ND, Sun J, Shukla SA, Gjini E, Li S, Giobbie-Hurder A, Wucherpfennig K, Suva M, Fritsch E, Rodig S, et al. Effect of dexamethasone in glioblastoma (GBM) patients on systemic and intratumoral T-cell responses induced by personalized neoantigen-targeting vaccine. Journal of Clinical Oncology. 36: 2020-2020. DOI: 10.1200/Jco.2018.36.15_Suppl.2020  0.342
2018 Keskin DB, Tirosh I, Anandappa A, Sun J, Mathewson ND, Shukla SA, Gjini E, Li S, Li L, Giobbie-Hurder A, Le PM, Hu Z, Zhang W, Olive O, McCluskey C, et al. Abstract 5631: Personal neoantigen-targeting vaccination generates neoepitope-specific T cell responses in tumors of patients with glioblastoma Cancer Research. 78: 5631-5631. DOI: 10.1158/1538-7445.Am2018-5631  0.404
2018 Li S, Sun J, Anandappa A, Spiro O, Leshchiner I, Datta K, Bao Y, Hu Z, Hacohen N, Mathewson ND, Tirosh I, Wucherpfennig K, Regev A, Suva M, Keskin DB, et al. Abstract 5387: Novel targeted single-cell TCR sequencing method used for analysis of a T cell infiltrate from a glioblastoma patient Cancer Research. 78: 5387-5387. DOI: 10.1158/1538-7445.Am2018-5387  0.457
2018 Reardon D, Keskin D, Tirosh I, Anandappa A, Mathewson N, Sun J, Shukla S, Gjini E, Li S, Giobbie-Hurder A, McCluskey C, Chiocca EA, Neuberg D, Wucherpfennig K, Suva M, et al. ATIM-32. PERSONALIZED NEOANTIGEN-TARGETING VACCINE GENERATES ROBUST SYSTEMIC AND INTRATUMORAL T CELL RESPONSES IN GLIOBLASTOMA (GBM) PATIENTS Neuro-Oncology. 20: vi8-vi8. DOI: 10.1093/Neuonc/Noy148.027  0.366
2017 Bae J, Hideshima T, Zhang GL, Zhou J, Keskin DB, Munshi NC, Anderson KC. Identification and characterization of HLA-A24 specific XBP1, CD138 (Syndecan-1), and CS1 (SLAMF7) peptides inducing antigens-specific memory cytotoxic T lymphocytes targeting multiple myeloma. Leukemia. PMID 29089645 DOI: 10.1038/Leu.2017.316  0.396
2017 Yoshikawa A, Bi K, Keskin DB, Zhang G, Reinhold B, Reinherz EL. TCR-pMHC encounter differentially regulates transcriptomes of(-) tissue-resident CD8 T cells. European Journal of Immunology. PMID 28872670 DOI: 10.1002/Eji.201747174  0.383
2017 Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, et al. An immunogenic personal neoantigen vaccine for patients with melanoma. Nature. PMID 28678778 DOI: 10.1038/Nature22991  0.453
2017 Abelin JG, Keskin DB, Sarkizova S, Hartigan CR, Zhang W, Sidney J, Stevens J, Lane W, Zhang GL, Eisenhaure TM, Clauser KR, Hacohen N, Rooney MS, Carr SA, Wu CJ. Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction. Immunity. 46: 315-326. PMID 28228285 DOI: 10.1016/J.Immuni.2017.02.007  0.37
2017 Hu Z, Sun J, Kim J, Anandappa AJ, Leet D, Williams L, Bozym DJ, Chen C, Zhang W, Tabbaa D, Bachireddy P, Shukla S, Steelman S, Keskin D, Wu CJ. Defining the Diversity and Specificity of Neoantigen-Specific T Cells in Chronic Lymphocytic Leukemia Blood. 130: 386-386. DOI: 10.1182/Blood.V130.Suppl_1.386.386  0.479
2017 Rooney MS, Abelin J, Sarkizova S, Keskin D, Hartigan C, Zhang W, Sidney J, Lane W, Stevens J, Zhang GL, Clauser K, Hacohen N, Carr S, Wu C. Abstract LB-179: Next-generation epitope prediction using mass spectrometry and integrative genomics Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-179  0.36
2016 Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Fritsch E, Hacohen N, Wu CJ. Abstract PR02: A personalized neoantigen vaccine in patients with high risk melanoma Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-Pr02  0.376
2016 Rooney MS, Abelin JG, Keskin DB, Sarkizova S, Hartigan C, Zhang W, Sidney J, Stevens J, Lane WJ, Zhang GL, Clauser KR, Hacohen N, Carr SA, Wu CJ. Abstract B089: High-throughput profiling of HLA allele-specific peptides by MS for improved epitope prediction Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B089  0.369
2015 Bae J, Keskin DB, Cowens K, Lee AH, Dranoff G, Munshi NC, Anderson KC. Lenalidomide Polarizes Th1-specific Anti-tumor Immune Response and Expands XBP1 Antigen-Specific Central Memory CD3(+)CD8(+) T cells against Various Solid Tumors. Journal of Leukemia (Los Angeles, Calif.). 3. PMID 27668268 DOI: 10.4172/2329-6917.1000178  0.389
2015 Tabansky I, Messina MD, Bangeranye C, Goldstein J, Blitz-Shabbir KM, Machado S, Jeganathan V, Wright P, Najjar S, Cao Y, Sands W, Keskin DB, Stern JN. Advancing drug delivery systems for the treatment of multiple sclerosis. Immunologic Research. PMID 26475738 DOI: 10.1007/S12026-015-8719-0  0.303
2015 Keskin DB, Reinhold BB, Zhang GL, Ivanov AR, Karger BL, Reinherz EL. Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity. Proceedings of the National Academy of Sciences of the United States of America. 112: 2151-6. PMID 25646416 DOI: 10.1073/Pnas.1423482112  0.447
2015 Das DK, Feng Y, Mallis RJ, Li X, Keskin DB, Hussey RE, Brady SK, Wang JH, Wagner G, Reinherz EL, Lang MJ. Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime. Proceedings of the National Academy of Sciences of the United States of America. 112: 1517-22. PMID 25605925 DOI: 10.1073/Pnas.1424829112  0.392
2014 Bae J, Samur M, Munshi A, Hideshima T, Keskin D, Kimmelman A, Lee AH, Dranoff G, Anderson KC, Munshi NC. Heteroclitic XBP1 peptides evoke tumor-specific memory cytotoxic T lymphocytes against breast cancer, colon cancer, and pancreatic cancer cells. Oncoimmunology. 3: e970914. PMID 25941601 DOI: 10.4161/21624011.2014.970914  0.404
2014 Zhang GL, Keskin DB, Lin HN, Lin HH, DeLuca DS, Leppanen S, Milford EL, Reinherz EL, Brusic V. Human leukocyte antigen typing using a knowledge base coupled with a high-throughput oligonucleotide probe array analysis. Frontiers in Immunology. 5: 597. PMID 25505899 DOI: 10.3389/Fimmu.2014.00597  0.331
2014 Reinherz EL, Keskin DB, Reinhold B. Forward Vaccinology: CTL Targeting Based upon Physical Detection of HLA-Bound Peptides. Frontiers in Immunology. 5: 418. PMID 25237310 DOI: 10.3389/Fimmu.2014.00418  0.425
2014 Rajasagi M, Shukla SA, Fritsch EF, Keskin DB, DeLuca D, Carmona E, Zhang W, Sougnez C, Cibulskis K, Sidney J, Stevenson K, Ritz J, Neuberg D, Brusic V, Gabriel S, et al. Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia. Blood. 124: 453-62. PMID 24891321 DOI: 10.1182/Blood-2014-04-567933  0.423
2014 Brazin KN, Mallis RJ, Li C, Keskin DB, Arthanari H, Gao Y, Wu SL, Karger BL, Wagner G, Reinherz EL. Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments. The Journal of Biological Chemistry. 289: 18880-92. PMID 24849600 DOI: 10.1074/Jbc.M114.574996  0.35
2014 Zhang GL, Riemer AB, Keskin DB, Chitkushev L, Reinherz EL, Brusic V. HPVdb: a data mining system for knowledge discovery in human papillomavirus with applications in T cell immunology and vaccinology. Database : the Journal of Biological Databases and Curation. 2014: bau031. PMID 24705205 DOI: 10.1093/Database/Bau031  0.357
2012 Cai A, Keskin DB, DeLuca DS, Alonso A, Zhang W, Zhang GL, Hammond NN, Nardi V, Stone RM, Neuberg D, Sidney J, Brusic V, Wu CJ. Mutated BCR-ABL generates immunogenic T-cell epitopes in CML patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5761-72. PMID 22912393 DOI: 10.1158/1078-0432.Ccr-12-1182  0.351
2012 Zakka LR, Fradkov E, Keskin DB, Tabansky I, Stern JN, Ahmed AR. The role of natural killer cells in autoimmune blistering diseases. Autoimmunity. 45: 44-54. PMID 21923616 DOI: 10.3109/08916934.2011.606446  0.422
2012 Rajasagi M, Keskin D, Kim J, Zhang W, Shukla S, DeLuca D, Sidney J, Brusic V, Neuberg DS, Getz G, Lander ES, Hacohen N, Wu CJ. Systematic Identification of Personal Mutated Tumor-Specific Neoantigens in CLL Blood. 120: 954-954. DOI: 10.1182/Blood.V120.21.954.954  0.426
2011 Keskin DB, Reinhold B, Lee SY, Zhang G, Lank S, O'Connor DH, Berkowitz RS, Brusic V, Kim SJ, Reinherz EL. Direct identification of an HPV-16 tumor antigen from cervical cancer biopsy specimens. Frontiers in Immunology. 2: 75. PMID 22566864 DOI: 10.3389/Fimmu.2011.00075  0.35
2011 Olsen LR, Zhang GL, Keskin DB, Reinherz EL, Brusic V. Conservation analysis of dengue virus T-cell epitope-based vaccine candidates using Peptide block entropy. Frontiers in Immunology. 2: 69. PMID 22566858 DOI: 10.3389/Fimmu.2011.00069  0.404
2011 Touma M, Keskin DB, Shiroki F, Saito I, Koyasu S, Reinherz EL, Clayton LK. Impaired B cell development and function in the absence of IkappaBNS. Journal of Immunology (Baltimore, Md. : 1950). 187: 3942-52. PMID 21900180 DOI: 10.4049/Jimmunol.1002109  0.37
2011 Zhang GL, Lin HH, Keskin DB, Reinherz EL, Brusic V. Dana-Farber repository for machine learning in immunology. Journal of Immunological Methods. 374: 18-25. PMID 21782820 DOI: 10.1016/J.Jim.2011.07.007  0.32
2011 Zhang Z, Tongchusak S, Mizukami Y, Kang YJ, Ioji T, Touma M, Reinhold B, Keskin DB, Reinherz EL, Sasada T. Induction of anti-tumor cytotoxic T cell responses through PLGA-nanoparticle mediated antigen delivery. Biomaterials. 32: 3666-78. PMID 21345488 DOI: 10.1016/J.Biomaterials.2011.01.067  0.403
2011 Zhang GL, DeLuca DS, Keskin DB, Chitkushev L, Zlateva T, Lund O, Reinherz EL, Brusic V. MULTIPRED2: a computational system for large-scale identification of peptides predicted to bind to HLA supertypes and alleles. Journal of Immunological Methods. 374: 53-61. PMID 21130094 DOI: 10.1016/J.Jim.2010.11.009  0.374
2010 Zakka LR, Keskin DB, Reche PA, Ahmed AR. Relationship between target antigens and major histocompatibility complex (MHC) class II genes in producing two pathogenic antibodies simultaneously. Clinical and Experimental Immunology. 162: 224-236. PMID 21069937 DOI: 10.1111/J.1365-2249.2010.04239.X  0.307
2010 Stern JN, Keskin DB, Kato Z, Waldner H, Schallenberg S, Anderson A, von Boehmer H, Kretschmer K, Strominger JL. Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 17280-5. PMID 20855626 DOI: 10.1073/Pnas.1010263107  0.49
2010 Riemer AB, Keskin DB, Zhang G, Handley M, Anderson KS, Brusic V, Reinhold B, Reinherz EL. A conserved E7-derived cytotoxic T lymphocyte epitope expressed on human papillomavirus 16-transformed HLA-A2+ epithelial cancers. The Journal of Biological Chemistry. 285: 29608-22. PMID 20615877 DOI: 10.1074/Jbc.M110.126722  0.377
2010 Ofran Y, Kim HT, Brusic V, Blake L, Mandrell M, Wu CJ, Sarantopoulos S, Bellucci R, Keskin DB, Soiffer RJ, Antin JH, Ritz J. Diverse patterns of T-cell response against multiple newly identified human Y chromosome-encoded minor histocompatibility epitopes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 1642-51. PMID 20160060 DOI: 10.1158/1078-0432.Ccr-09-2701  0.384
2010 Cai A, Keskin D, Alonso A, DeLuca D, Zhang W, Lokko N, Nardi V, Stone RM, Sidney J, Brusic V, Wu CJ. Peptides Derived From Mutated BCR-ABL Elicit T Cell Immunity In CML Patients Blood. 116: 887-887. DOI: 10.1182/Blood.V116.21.887.887  0.433
2010 Ochiai K, Singh H, Vu T, Funnell A, Gatto D, Brink R, Pearson R, Crossley M, Minamino K, Adachi T, Nagaoka K, Takahara K, Taki S, Inaba K, Touma M, ... Keskin DB, et al. B cell development (WS-030) Chairpersons: Daisuke Kitamura, David Gray International Immunology. 22. DOI: 10.1093/Intimm/Dxq187  0.316
2010 Riemer A, Keskin D, Reinhold B, Zhang G, Anderson K, Brusic V, Reinherz E. Mass Spectrometry Identifies a Single Dominant T Cell Epitope on HPV16-transformed HLA-A0201+ Tumor Cells Clinical Immunology. 135: S106. DOI: 10.1016/J.Clim.2010.03.319  0.375
2009 Gürcan HM, Keskin DB, Stern JN, Nitzberg MA, Shekhani H, Ahmed AR. A review of the current use of rituximab in autoimmune diseases. International Immunopharmacology. 9: 10-25. PMID 19000786 DOI: 10.1016/J.Intimp.2008.10.004  0.316
2008 Stern JN, Keskin DB, Barteneva N, Zuniga J, Yunis EJ, Ahmed AR. Possible role of natural killer cells in pemphigus vulgaris - preliminary observations. Clinical and Experimental Immunology. 152: 472-81. PMID 18373702 DOI: 10.1111/J.1365-2249.2008.03638.X  0.404
2008 Stern JN, Keskin DB, Zhang H, Lv H, Kato Z, Strominger JL. Amino acid copolymer-specific IL-10-secreting regulatory T cells that ameliorate autoimmune diseases in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 5172-6. PMID 18362339 DOI: 10.1073/Pnas.0712131105  0.352
2007 Touma M, Antonini V, Kumar M, Osborn SL, Bobenchik AM, Keskin DB, Connolly JE, Grusby MJ, Reinherz EL, Clayton LK. Functional role for I kappa BNS in T cell cytokine regulation as revealed by targeted gene disruption. Journal of Immunology (Baltimore, Md. : 1950). 179: 1681-92. PMID 17641034 DOI: 10.4049/Jimmunol.179.3.1681  0.371
2007 Keskin DB, Allan DS, Rybalov B, Andzelm MM, Stern JN, Kopcow HD, Koopman LA, Strominger JL. TGFbeta promotes conversion of CD16+ peripheral blood NK cells into CD16- NK cells with similarities to decidual NK cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 3378-83. PMID 17360654 DOI: 10.1073/Pnas.0611098104  0.358
2007 Keskin DB, Marshall B, Munn D, Mellor AL, Gearhart DA. Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase. Cellular & Molecular Biology Letters. 12: 82-102. PMID 17103092 DOI: 10.2478/S11658-006-0048-9  0.518
2006 Reche PA, Keskin DB, Hussey RE, Ancuta P, Gabuzda D, Reinherz EL. Elicitation from virus-naive individuals of cytotoxic T lymphocytes directed against conserved HIV-1 epitopes. Medical Immunology (London, England). 5: 1. PMID 16674822 DOI: 10.1186/1476-9433-5-1  0.329
2005 Illes Z, Stern JN, Keskin DB, Reddy J, Brosnan CF, Waldner H, Santambrogio L, Kuchroo VK, Strominger JL. Copolymer effects on microglia and T cells in the central nervous system of humanized mice. European Journal of Immunology. 35: 3683-93. PMID 16259003 DOI: 10.1002/Eji.200526121  0.429
2005 Stern JN, Illés Z, Reddy J, Keskin DB, Fridkis-Hareli M, Kuchroo VK, Strominger JL. Peptide 15-mers of defined sequence that substitute for random amino acid copolymers in amelioration of experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 102: 1620-5. PMID 15665083 DOI: 10.1073/Pnas.0409022102  0.395
2004 Stern JN, Illés Z, Reddy J, Keskin DB, Sheu E, Fridkis-Hareli M, Nishimura H, Brosnan CF, Santambrogio L, Kuchroo VK, Strominger JL. Amelioration of proteolipid protein 139-151-induced encephalomyelitis in SJL mice by modified amino acid copolymers and their mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 101: 11743-8. PMID 15292514 DOI: 10.1073/Pnas.0403832101  0.414
2003 Mellor AL, Munn D, Chandler P, Keskin D, Johnson T, Marshall B, Jhaver K, Baban B. Tryptophan catabolism and T cell responses. Advances in Experimental Medicine and Biology. 527: 27-35. PMID 15206713 DOI: 10.1007/978-1-4615-0135-0_3  0.621
2002 Mellor AL, Chandler P, Lee GK, Johnson T, Keskin DB, Lee J, Munn DH. Indoleamine 2,3-dioxygenase, immunosuppression and pregnancy. Journal of Reproductive Immunology. 57: 143-50. PMID 12385839 DOI: 10.1016/S0165-0378(02)00040-2  0.554
2002 Munn DH, Sharma MD, Lee JR, Jhaver KG, Johnson TS, Keskin DB, Marshall B, Chandler P, Antonia SJ, Burgess R, Slingluff CL, Mellor AL. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science (New York, N.Y.). 297: 1867-70. PMID 12228717 DOI: 10.1126/Science.1073514  0.617
2002 Mellor AL, Keskin DB, Johnson T, Chandler P, Munn DH. Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 168: 3771-6. PMID 11937528 DOI: 10.4049/Jimmunol.168.8.3771  0.624
2002 Fallarino F, Vacca C, Orabona C, Belladonna ML, Bianchi R, Marshall B, Keskin DB, Mellor AL, Fioretti MC, Grohmann U, Puccetti P. Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. International Immunology. 14: 65-8. PMID 11751753 DOI: 10.1093/Intimm/14.1.65  0.613
2001 Marshall B, Keskin DB, Mellor AL. Regulation of prostaglandin synthesis and cell adhesion by a tryptophan catabolizing enzyme. Bmc Biochemistry. 2: 5. PMID 11375052 DOI: 10.1186/1471-2091-2-5  0.529
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