Dirk Bohmann - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Genetics, Cell Biology

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cheng Y, Pitoniak A, Wang J, Bohmann D. Preserving transcriptional stress responses as an anti-aging strategy. Aging Cell. e13297. PMID 33474790 DOI: 10.1111/acel.13297  0.336
2020 Mello S, Bohmann D. Counting the Minutes. Elife. 9. PMID 31909709 DOI: 10.7554/Elife.53348  0.34
2018 Chatterjee N, Bohmann D. BET-ting on Nrf2: How Nrf2 Signaling can Influence the Therapeutic Activities of BET Protein Inhibitors. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 29603290 DOI: 10.1002/Bies.201800007  0.755
2017 Li X, Eberhardt A, Hansen JN, Bohmann D, Li H, Schor NF. Methylation of the phosphatase-transcription activator EYA1 by protein arginine methyltransferase 1: mechanistic, functional, and structural studies. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28213359 DOI: 10.1096/Fj.201601050Rr  0.383
2016 Chatterjee N, Tian M, Spirohn K, Boutros M, Bohmann D. Keap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain Protein. Plos Genetics. 12: e1006072. PMID 27233051 DOI: 10.1371/Journal.Pgen.1006072  0.773
2016 Li X, Chatterjee N, Spirohn K, Boutros M, Bohmann D. Cdk12 Is A Gene-Selective RNA Polymerase II Kinase That Regulates a Subset of the Transcriptome, Including Nrf2 Target Genes. Scientific Reports. 6: 21455. PMID 26911346 DOI: 10.1038/Srep21455  0.777
2016 Li X, Chatterjee N, Spirohn K, Boutros M, Bohmann D. Cdk12 is a gene-selective RNA polymerase II kinase that regulates a subset of the transcriptome, including Nrf2 target genes Scientific Reports. 6. DOI: 10.1038/srep21455  0.738
2015 Pitoniak A, Bohmann D. Mechanisms and functions of Nrf2 signaling in Drosophila. Free Radical Biology & Medicine. 88: 302-13. PMID 26117322 DOI: 10.1016/J.Freeradbiomed.2015.06.020  0.495
2014 Bohmann D, Dhillon P. Towards a systems-level understanding of aging and cancer: an interview with Dirk Bohmann Disease Models & Mechanisms. 7: 499-502. PMID 24795432 DOI: 10.1242/Dmm.016329  0.306
2013 Tsakiri EN, Sykiotis GP, Papassideri IS, Terpos E, Dimopoulos MA, Gorgoulis VG, Bohmann D, Trougakos IP. Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging. Aging Cell. 12: 802-13. PMID 23738891 DOI: 10.1111/Acel.12111  0.403
2013 Rahman MM, Sykiotis GP, Nishimura M, Bodmer R, Bohmann D. Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes. Aging Cell. 12: 554-62. PMID 23521918 DOI: 10.1111/Acel.12078  0.429
2013 Tsakiri EN, Sykiotis GP, Papassideri IS, Gorgoulis VG, Bohmann D, Trougakos IP. Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2407-20. PMID 23457214 DOI: 10.1096/Fj.12-221408  0.357
2013 Tsakiri EN, Terpos E, Sykiotis GP, Papassideri IS, Gorgoulis VG, Bohmann D, Dimopoulos MA, Trougakos IP. Molecular Analyses Of The Effects Induced By Orally Administered Bortezomib In Drosophila Flies: A Novel In Vivo Experimental Platform To Screen For The Tissue- and Age-Dependent Effects Of Proteasome Inhibitors Blood. 122: 2910-2910. DOI: 10.1182/Blood.V122.21.2910.2910  0.42
2013 Tsakiri EN, Sykiotis GP, Papassideri IS, Terpos E, Dimopoulos MA, Gorgoulis VG, Bohmann D, Trougakos IP. Differential regulation of the proteasome and of antioxidant responses during aging in the somatic tissues and the gonads of Drosophila Free Radical Biology and Medicine. 65: S52-S53. DOI: 10.1016/J.Freeradbiomed.2013.08.089  0.33
2012 Chatterjee N, Bohmann D. A versatile ΦC31 based reporter system for measuring AP-1 and Nrf2 signaling in Drosophila and in tissue culture. Plos One. 7: e34063. PMID 22509270 DOI: 10.1371/Journal.Pone.0034063  0.77
2011 Barone MC, Sykiotis GP, Bohmann D. Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease. Disease Models & Mechanisms. 4: 701-7. PMID 21719443 DOI: 10.1242/Dmm.007575  0.332
2011 Schreck I, Al-Rawi M, Mingot JM, Scholl C, Diefenbacher ME, O'Donnell P, Bohmann D, Weiss C. c-Jun localizes to the nucleus independent of its phosphorylation by and interaction with JNK and vice versa promotes nuclear accumulation of JNK. Biochemical and Biophysical Research Communications. 407: 735-40. PMID 21439937 DOI: 10.1016/J.Bbrc.2011.03.092  0.409
2011 Hochmuth CE, Biteau B, Bohmann D, Jasper H. Redox regulation by keap1 and Nrf2 controls intestinal stem cell proliferation in drosophila Cell Stem Cell. 8: 188-199. PMID 21295275 DOI: 10.1016/J.Stem.2010.12.006  0.422
2011 Sykiotis GP, Habeos IG, Samuelson AV, Bohmann D. The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation. Current Opinion in Clinical Nutrition and Metabolic Care. 14: 41-8. PMID 21102319 DOI: 10.1097/Mco.0B013E32834136F2  0.495
2010 Sykiotis GP, Bohmann D. Stress-activated cap'n'collar transcription factors in aging and human disease. Science Signaling. 3: re3. PMID 20215646 DOI: 10.1126/Scisignal.3112Re3  0.394
2010 Wang Q, Uhlirova M, Bohmann D. Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis. Developmental Cell. 18: 157-64. PMID 20152186 DOI: 10.1016/J.Devcel.2009.11.004  0.343
2010 Sekyrova P, Bohmann D, Jindra M, Uhlirova M. Interaction between Drosophila bZIP proteins Atf3 and Jun prevents replacement of epithelial cells during metamorphosis. Development (Cambridge, England). 137: 141-50. PMID 20023169 DOI: 10.1242/Dev.037861  0.483
2009 Wu H, Wang MC, Bohmann D. JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy. Mechanisms of Development. 126: 624-37. PMID 19540338 DOI: 10.1016/J.Mod.2009.06.1082  0.618
2008 Sykiotis GP, Bohmann D. Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila. Developmental Cell. 14: 76-85. PMID 18194654 DOI: 10.1016/J.Devcel.2007.12.002  0.4
2007 Luo X, Puig O, Hyun J, Bohmann D, Jasper H. Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation. The Embo Journal. 26: 380-90. PMID 17183370 DOI: 10.1038/Sj.Emboj.7601484  0.758
2006 Uhlirova M, Bohmann D. JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila. The Embo Journal. 25: 5294-304. PMID 17082773 DOI: 10.1038/Sj.Emboj.7601401  0.405
2006 Hyun J, Bécam I, Yanicostas C, Bohmann D. Control of G2/M transition by Drosophila Fos. Molecular and Cellular Biology. 26: 8293-302. PMID 16966382 DOI: 10.1128/Mcb.02455-05  0.751
2006 Miotto B, Sagnier T, Berenger H, Bohmann D, Pradel J, Graba Y. Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis. Genes & Development. 20: 101-12. PMID 16391236 DOI: 10.1101/Gad.359506  0.51
2006 Homsy JG, Jasper H, Peralta XG, Wu H, Kiehart DP, Bohmann D. JNK signaling coordinates integrin and actin functions during Drosophila embryogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 427-34. PMID 16317725 DOI: 10.1002/Dvdy.20649  0.779
2005 Uhlirova M, Jasper H, Bohmann D. Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model. Proceedings of the National Academy of Sciences of the United States of America. 102: 13123-8. PMID 16150723 DOI: 10.1073/Pnas.0504170102  0.333
2005 Hyun J, Jasper H, Bohmann D. DREF is required for efficient growth and cell cycle progression in Drosophila imaginal discs. Molecular and Cellular Biology. 25: 5590-8. PMID 15964814 DOI: 10.1128/Mcb.25.13.5590-5598.2005  0.765
2005 Etter PD, Narayanan R, Navratilova Z, Patel C, Bohmann D, Jasper H, Ramaswami M. Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons. Bmc Neuroscience. 6: 39. PMID 15932641 DOI: 10.1186/1471-2202-6-39  0.448
2005 Wang MC, Bohmann D, Jasper H. JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell. 121: 115-25. PMID 15820683 DOI: 10.1016/J.Cell.2005.02.030  0.42
2004 Portman DS, Bohmann D. Toward the computable transcriptome. Molecular Cell. 14: 693-4. PMID 15200946 DOI: 10.1016/J.Molcel.2004.06.013  0.366
2004 Su C, Gao G, Schneider S, Helt C, Weiss C, O'Reilly MA, Bohmann D, Zhao J. DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway. The Embo Journal. 23: 1133-43. PMID 14976556 DOI: 10.1038/Sj.Emboj.7600120  0.405
2004 Weiss C, Bohmann D. Deregulated repression of c-Jun provides a potential link to its role in tumorigenesis. Cell Cycle (Georgetown, Tex.). 3: 111-3. PMID 14712066 DOI: 10.4161/Cc.3.2.648  0.4
2003 Wang MC, Bohmann D, Jasper H. JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila. Developmental Cell. 5: 811-6. PMID 14602080 DOI: 10.1016/S1534-5807(03)00323-X  0.443
2003 Weiss C, Schneider S, Wagner EF, Zhang X, Seto E, Bohmann D. JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun. The Embo Journal. 22: 3686-95. PMID 12853483 DOI: 10.1093/Emboj/Cdg364  0.435
2002 Jasper H, Benes V, Atzberger A, Sauer S, Ansorge W, Bohmann D. A genomic switch at the transition from cell proliferation to terminal differentiation in the Drosophila eye. Developmental Cell. 3: 511-21. PMID 12408803 DOI: 10.1016/S1534-5807(02)00297-6  0.426
2002 Gallo A, Cuozzo C, Esposito I, Maggiolini M, Bonofiglio D, Vivacqua A, Garramone M, Weiss C, Bohmann D, Musti AM. Menin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activation. Oncogene. 21: 6434-45. PMID 12226747 DOI: 10.1038/Sj.Onc.1205822  0.429
2002 Lafarga M, Berciano MT, Pena E, Mayo I, Castaño JG, Bohmann D, Rodrigues JP, Tavanez JP, Carmo-Fonseca M. Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome. Molecular Biology of the Cell. 13: 2771-82. PMID 12181345 DOI: 10.1091/Mbc.E02-03-0122  0.365
2002 Gritzan U, Weiss C, Brennecke J, Bohmann D. Transrepression of AP-1 by nuclear receptors in Drosophila. Mechanisms of Development. 115: 91-100. PMID 12049770 DOI: 10.1016/S0925-4773(02)00116-8  0.327
2002 Ciapponi L, Bohmann D. An essential function of AP-1 heterodimers in Drosophila development. Mechanisms of Development. 115: 35-40. PMID 12049765 DOI: 10.1016/S0925-4773(02)00093-X  0.415
2002 Westermarck J, Weiss C, Saffrich R, Kast J, Musti AM, Wessely M, Ansorge W, Séraphin B, Wilm M, Valdez BC, Bohmann D. The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription. The Embo Journal. 21: 451-60. PMID 11823437 DOI: 10.1093/Emboj/21.3.451  0.441
2001 Jasper H, Benes V, Schwager C, Sauer S, Clauder-Münster S, Ansorge W, Bohmann D. The genomic response of the Drosophila embryo to JNK signaling. Developmental Cell. 1: 579-86. PMID 11703947 DOI: 10.1016/S1534-5807(01)00045-4  0.501
2001 Ciapponi L, Jackson DB, Mlodzik M, Bohmann D. Drosophila Fos mediates ERK and JNK signals via distinct phosphorylation sites. Genes & Development. 15: 1540-53. PMID 11410534 DOI: 10.1101/Gad.886301  0.41
2001 Kockel L, Homsy JG, Bohmann D. Drosophila AP-1: lessons from an invertebrate. Oncogene. 20: 2347-64. PMID 11402332 DOI: 10.1038/Sj.Onc.1204300  0.764
2001 Leppä S, Eriksson M, Saffrich R, Ansorge W, Bohmann D. Complex functions of AP-1 transcription factors in differentiation and survival of PC12 cells. Molecular and Cellular Biology. 21: 4369-78. PMID 11390664 DOI: 10.1128/Mcb.21.13.4369-4378.2001  0.437
2001 Mihaly J, Kockel L, Gaengel K, Weber U, Bohmann D, Mlodzik M. The role of the Drosophila TAK homologue dTAK during development. Mechanisms of Development. 102: 67-79. PMID 11287182 DOI: 10.1016/S0925-4773(01)00285-4  0.446
2000 Barilá D, Mangano R, Gonfloni S, Kretzschmar J, Moro M, Bohmann D, Superti‐Furga G. A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK. The Embo Journal. 19: 273-281. PMID 10637231 DOI: 10.1093/Emboj/19.2.273  0.369
1999 Leppä S, Bohmann D. Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. Oncogene. 18: 6158-6162. PMID 10557107 DOI: 10.1038/Sj.Onc.1203173  0.403
1998 Leppä S, Saffrich R, Ansorge W, Bohmann D. Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation The Embo Journal. 17: 4404-4413. PMID 9687508 DOI: 10.1093/Emboj/17.15.4404  0.434
1997 Riesgo-Escovar JR, Hafen E, Hou XS, Goldstein ES, Perrimon N, Glise B, Noselli S, Kockel L, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D. Connecting up the pathways in Drosophila development. Trends in Cell Biology. 7: 421-2. PMID 17708993 DOI: 10.1016/S0962-8924(97)88135-4  0.492
1997 Isaksson A, Peverali FA, Kockel L, Mlodzik M, Bohmann D. The deubiquitination enzyme fat facets negatively regulates RTK/Ras/MAPK signalling during Drosophila eye development. Mechanisms of Development. 68: 59-67. PMID 9431804 DOI: 10.1016/S0925-4773(97)00126-3  0.413
1997 Zeitlinger J, Kockel L, Peverali FA, Jackson DB, Mlodzik M, Bohmann D. Defective dorsal closure and loss of epidermal decapentaplegic expression in Drosophila fos mutants. The Embo Journal. 16: 7393-401. PMID 9405368 DOI: 10.1093/Emboj/16.24.7393  0.4
1997 Kockel L, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D. Jun in Drosophila development: redundant and nonredundant functions and regulation by two MAPK signal transduction pathways. Genes & Development. 11: 1748-58. PMID 9224723 DOI: 10.1101/Gad.11.13.1748  0.428
1997 Kockel L, Vorbrüggen G, Jäckle H, Mlodzik M, Bohmann D. Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development. Genes & Development. 11: 1140-7. PMID 9159395 DOI: 10.1101/Gad.11.9.1140  0.4
1997 Eresh S, Riese J, Jackson DB, Bohmann D, Bienz M. A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction. The Embo Journal. 16: 2014-22. PMID 9155027 DOI: 10.1093/Emboj/16.8.2014  0.481
1997 Musti AM, Treier M, Bohmann D. Reduced Ubiquitin-Dependent Degradation of c-Jun After Phosphorylation by MAP Kinases Science. 275: 400-402. PMID 8994040 DOI: 10.1126/Science.275.5298.400  0.458
1996 Musti AM, Treier M, Peverali FA, Bohmann D. Differential regulation of c-Jun and JunD by ubiquitin-dependent protein degradation. Biological Chemistry. 377: 619-624. PMID 8922589 DOI: 10.1515/Bchm3.1996.377.10.619  0.403
1996 Isaksson A, Musti AM, Bohmann D. Ubiquitin in signal transduction and cell transformation. Biochimica Et Biophysica Acta. 1288. PMID 8764838 DOI: 10.1016/0304-419X(96)00011-X  0.462
1996 Peverali FA, Isaksson A, Papavassiliou AG, Plastina P, Staszewski LM, Mlodzik M, Bohmann D. Phosphorylation of Drosophila Jun by the MAP kinase rolled regulates photoreceptor differentiation. The Embo Journal. 15: 3943-50. PMID 8670899 DOI: 10.1002/J.1460-2075.1996.Tb00768.X  0.379
1995 Treier M, Bohmann D, Mlodzik M. JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye. Cell. 83: 753-60. PMID 8521492 DOI: 10.1016/0092-8674(95)90188-4  0.403
1995 Papavassiliou AG, Treier M, Bohmann D. Intramolecular signal transduction in c‐Jun. The Embo Journal. 14: 2014-2019. DOI: 10.1002/J.1460-2075.1995.Tb07193.X  0.35
1994 Treier M, Staszewski LM, Bohmann D. Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain Cell. 78: 787-798. PMID 8087846 DOI: 10.1016/S0092-8674(94)90502-9  0.317
1994 Bohmann D, Ellis MC, Staszewski LM, Mlodzik M. Drosophila Jun mediates Ras-dependent photoreceptor determination. Cell. 78: 973-86. PMID 7923366 DOI: 10.1016/0092-8674(94)90273-9  0.382
1993 Smith SE, Papavassiliou AG, Bohmann D. Different TRE-related elements are distinguished by sets of DNA-binding proteins with overlapping sequence specificity Nucleic Acids Research. 21: 1581-1585. PMID 8479909 DOI: 10.1093/Nar/21.7.1581  0.362
1992 Papavassiliou AG, Treier M, Chavrier C, Bohmann D. Targeted degradation of c-Fos, but not v-Fos, by a phosphorylation-dependent signal on c-Jun. Science. 258: 1941-1944. PMID 1470918 DOI: 10.1126/Science.1470918  0.379
1992 Papavassiliou AG, Chavrier C, Bohmann D. Phosphorylation state and DNA-binding activity of c-Jun depend on the intracellular concentration of binding sites. Proceedings of the National Academy of Sciences of the United States of America. 89: 11562-11565. PMID 1454848 DOI: 10.1073/Pnas.89.23.11562  0.333
1992 Papavassiliou AG, Bohmann K, Bohmann D. Determining the effect of inducible protein phosphorylation on the DNA-binding activity of transcription factors. Analytical Biochemistry. 203: 302-309. PMID 1416026 DOI: 10.1016/0003-2697(92)90317-Z  0.461
1989 Bohmann D, Tjian R. Biochemical analysis of transcriptional activation by Jun: Differential activity of c- and v-Jun Cell. 59: 709-717. PMID 2510934 DOI: 10.1016/0092-8674(89)90017-2  0.417
1988 Bohmann D, Admon A, Turner DR, Tjian R. Transcriptional regulation by the AP-1 family of enhancer-binding proteins: A nuclear target for signal transduction Cold Spring Harbor Symposia On Quantitative Biology. 53: 695-700. PMID 3151183 DOI: 10.1101/Sqb.1988.053.01.079  0.427
1988 Rauscher FJ, Cohen DR, Curran T, Bos TJ, Vogt PK, Bohmann D, Tjian R, Franza BR. Fos-associated protein p39 is the product of the jun proto-oncogene. Science (New York, N.Y.). 240: 1010-6. PMID 3130660 DOI: 10.1126/Science.3130660  0.37
1988 Bos TJ, Bohmann D, Tsuchie H, Tijan R, Vogt PK. v-jun encodes a nuclear protein with enhancer binding properties of AP-1. Cell. 52: 705-712. PMID 2830989 DOI: 10.1016/0092-8674(88)90408-4  0.39
1988 Bohmann D, Bos TJ, Admon A, Nishimura T, Vogt PK, Tjian R. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science (New York, N.Y.). 238: 1386-92. PMID 2825349 DOI: 10.1126/Science.2825349  0.399
1987 Tebb G, Bohmann D, Mattaj IW. Only two of the four sites of interaction with nuclear factors within the Xenopus U2 gene promoter are necessary for efficient transcription. Nucleic Acids Research. 15: 6437-53. PMID 3627994 DOI: 10.1093/Nar/15.16.6437  0.395
1987 Bohmann D, Keller W, Dale T, Schöler HR, Tebb G, Mattaj IW. A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes. Nature. 325: 268-72. PMID 3027566 DOI: 10.1038/325268A0  0.436
1986 Schlokat U, Bohmann D, Schöler H, Gruss P. Nuclear factors binding specific sequences within the immunoglobulin enhancer interact differentially with other enhancer elements. The Embo Journal. 5: 3251-8. PMID 3102227 DOI: 10.1002/J.1460-2075.1986.Tb04636.X  0.387
1985 Shaw PE, Bohmann D, Sergeant A. The SV40 enhancer influences viral late transcription in vitro and in vivo but not on replicating templates. The Embo Journal. 4: 3247-3252. DOI: 10.1002/J.1460-2075.1985.Tb04073.X  0.402
1984 Sergeant A, Bohmann D, Zentgraf H, Weiher H, Keller W. A transcription enhancer acts in vitro over distances of hundreds of base-pairs on both circular and linear templates but not on chromatin-reconstituted DNA Journal of Molecular Biology. 180: 577-600. PMID 6098685 DOI: 10.1016/0022-2836(84)90028-7  0.383
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