Linda J. Metheny-Barlow - Publications

Affiliations: 
Cancer Biology Wake Forest University, Winston-Salem, NC, United States 
Area:
Cell Biology, Oncology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mackert JD, Stirling ER, Wilson AS, Westwood B, Zhao D, Lo HW, Metheny-Barlow L, Cook KL, Lesser GJ, Soto-Pantoja DR. Anti-CD47 immunotherapy as a therapeutic strategy for the treatment of breast cancer brain metastasis. Biorxiv : the Preprint Server For Biology. PMID 37546807 DOI: 10.1101/2023.07.25.550566  0.366
2021 Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Regua AT, Arrigo A, Anguelov M, et al. Correction: TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment. Oncogene. PMID 33654200 DOI: 10.1038/s41388-020-01620-5  0.443
2020 Su J, Song Q, Qasem S, O'Neill S, Lee J, Furdui CM, Pasche B, Metheny-Barlow L, Masters AH, Lo HW, Xing F, Watabe K, Miller LD, Tatter SB, Laxton AW, et al. Multi-Omics Analysis of Brain Metastasis Outcomes Following Craniotomy. Frontiers in Oncology. 10: 615472. PMID 33889540 DOI: 10.3389/fonc.2020.615472  0.307
2020 Renfrow JJ, Soike MH, West JL, Ramkissoon SH, Metheny-Barlow L, Mott RT, Kittel CA, D'Agostino RB, Tatter SB, Laxton AW, Frenkel MB, Hawkins GA, Herpai D, Sanders S, Sarkaria JN, et al. Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor. Scientific Reports. 10: 15195. PMID 32938997 DOI: 10.1038/S41598-020-72290-2  0.412
2020 Doheny DL, Sirkisoon SR, Rimkus T, Zhu D, Aguayo NR, Harrison A, Anguelov M, Manore S, Xing F, Metheny-Barlow LJ, Watabe K, Thomas A, Masters AH, Strowd R, Lo H. Abstract 5025: Antifungal ketoconazole inhibits tumor-specific transcription factor tGLI1 leading to suppression of breast cancer stem cells and brain metastasis Cancer Research. 80: 5025-5025. DOI: 10.1158/1538-7445.Am2020-5025  0.545
2019 Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Regua AT, Arrigo A, Anguelov M, et al. TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment. Oncogene. PMID 31462709 DOI: 10.1038/S41388-019-0959-3  0.54
2019 Sharma S, Wu SY, Jimenez H, Xing F, Zhu D, Liu Y, Wu K, Tyagi A, Zhao D, Lo HW, Metheny-Barlow L, Sun P, Bourland JD, Chan MD, Thomas A, et al. Ca and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF. Ebiomedicine. PMID 31129098 DOI: 10.1016/J.Ebiom.2019.05.038  0.436
2019 Dohm A, Su J, McTyre ER, Taylor JM, Miller LD, Petty WJ, Xing F, Lo HW, Metheny-Barlow LJ, O'Neill S, Bellinger C, Dotson T, Pasche B, Watabe K, Chan MD, et al. Identification of CD37, cystatin A, and IL-23A gene expression in association with brain metastasis: analysis of a prospective trial. The International Journal of Biological Markers. 1724600818803104. PMID 30854931 DOI: 10.1177/1724600818803104  0.324
2019 Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Anguelov M, Arrigo A, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Pasche BC, et al. Abstract 3689: Tumor-specific gain-of-function tGLI1 transcription factor is a novel mediator of breast cancer stem cells and a novel transcriptional activator of cancer stemness genes Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3689  0.432
2019 Sirkisoon S, Carpenter R, Rimkus T, Doheny D, Zhu D, Aguayo N, Anguelov M, Arrigo A, Regua A, Xing F, Chan M, Metheny-Barlow L, Watabe K, Lo H. BSCI-13. TUMOR-SPECIFIC tGLI1 TRANSCRIPTION FACTOR MEDIATES BREAST CANCER BRAIN METASTASIS VIA ACTIVATING METASTASIS-INITIATING CANCER STEM CELLS AND ASTROCYTES IN THE TUMOR MICROENVIRONMENT Neuro-Oncology Advances. 1: i3-i3. DOI: 10.1093/noajnl/vdz014.011  0.516
2019 Doheny D, Sirkisoon S, Rimkus T, Zhu D, Aguayo N, Harrison A, Anguelov M, Xing F, Metheny-Barlow L, Watabe K, Thomas A, Masters AH, Strowd R, Lo H. BSCI-02. tGLI1 IS A NOVEL, ACTIONABLE TARGET FOR THE TREATMENT OF BREAST CANCER BRAIN METASTASES Neuro-Oncology Advances. 1: i1-i1. DOI: 10.1093/noajnl/vdz014.001  0.443
2018 Shenker RF, Hughes RT, McTyre ER, Lanier C, Lo HW, Metheny-Barlow L, Su J, Thomas A, Brown DR, Avery T, Pasche B, Cramer CK, Laxton AW, Tatter SB, Watabe K, et al. Potential prognostic markers for survival and neurologic death in patients with breast cancer brain metastases who receive upfront SRS alone. Journal of Radiosurgery and Sbrt. 5: 277-283. PMID 30538888 DOI: 10.1016/J.Ijrobp.2018.07.926  0.415
2018 Cramer CK, Alphonse-Sullivan N, Isom S, Metheny-Barlow LJ, Cummings TL, Page BR, Brown DR, Blackstock AW, Peiffer AM, Strowd RE, Rapp S, Lesser GJ, Shaw EG, Chan MD. Safety of pioglitazone during and after radiation therapy in patients with brain tumors: a phase I clinical trial. Journal of Cancer Research and Clinical Oncology. PMID 30417218 DOI: 10.1007/S00432-018-2791-5  0.387
2018 Xing F, Liu Y, Wu SY, Wu K, Sharma S, Mo YY, Feng J, Sanders S, Jin G, Singh R, Vidi PA, Tyagi A, Chan MD, Ruiz J, Debinski W, ... ... Metheny-Barlow LJ, et al. Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis. Cancer Research. PMID 30026327 DOI: 10.1158/0008-5472.Can-18-1102  0.564
2018 Andrews RN, Caudell DL, Metheny-Barlow LJ, Peiffer AM, Tooze JA, Bourland JD, Hampson RE, Deadwyler SA, Cline JM. Fibronectin Produced by Cerebral Endothelial and Vascular Smooth Muscle Cells Contributes to Perivascular Extracellular Matrix in Late-Delayed Radiation-Induced Brain Injury. Radiation Research. PMID 30016219 DOI: 10.1667/Rr14961.1  0.435
2017 Okoukoni C, McTyre ER, Ayala Peacock DN, Peiffer AM, Strowd R, Cramer C, Hinson WH, Rapp S, Metheny-Barlow L, Shaw EG, Chan MD. Hippocampal dose volume histogram predicts Hopkins Verbal Learning Test scores after brain irradiation. Advances in Radiation Oncology. 2: 624-629. PMID 29204530 DOI: 10.1016/J.Adro.2017.08.013  0.319
2017 Carpenter RL, Sirkisoon S, Zhu D, Rimkus T, Harrison A, Anderson A, Paw I, Qasem S, Xing F, Liu Y, Chan M, Metheny-Barlow L, Pasche BC, Debinski W, Watabe K, et al. Combined inhibition of AKT and HSF1 suppresses breast cancer stem cells and tumor growth. Oncotarget. 8: 73947-73963. PMID 29088759 DOI: 10.18632/Oncotarget.18166  0.474
2017 Carpenter RL, Sirkisoon S, Zhu D, Rimkus T, Harrison A, Anderson A, Paw I, Qasem S, Xing F, Liu Y, Chan M, Metheny-Barlow L, Pasche BC, Debinski W, Watabe K, et al. Combined inhibition of AKT and HSF1 suppresses breast cancer stem cells and tumor growth. Oncotarget. PMID 28598816 DOI: 10.18632/oncotarget.18166  0.383
2017 Wang EC, Huang AJ, Huang KE, McTyre ER, Lo HW, Watabe K, Metheny-Barlow L, Laxton AW, Tatter SB, Strowd RE, Chan MD, Page BR. Leptomeningeal failure in patients with breast cancer receiving stereotactic radiosurgery for brain metastases. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. PMID 28511975 DOI: 10.1016/J.Jocn.2017.04.033  0.42
2017 Andrews RN, Metheny-Barlow LJ, Peiffer AM, Hanbury DB, Tooze JA, Bourland JD, Hampson RE, Deadwyler SA, Cline JM. Cerebrovascular Remodeling and Neuroinflammation is a Late Effect of Radiation-Induced Brain Injury in Non-Human Primates. Radiation Research. PMID 28398880 DOI: 10.1667/Rr14616.1  0.366
2017 Chen W, Gallagher P, Tallant A, Metheny-Barlow LJ. Abstract 5125: Muscadine grape extract inhibits breast cancer brain metastatic cells by multiple mechanisms Cancer Research. 77: 5125-5125. DOI: 10.1158/1538-7445.Am2017-5125  0.531
2017 Tallant EA, Deng G, Chen W, Metheny-Barlow LJ, Gallagher PE. Abstract 1227: Angiotensin-(1-7) reduces triple negative breast cancer brain metastatic growth in association with decreased c-Met signaling Cancer Research. 77: 1227-1227. DOI: 10.1158/1538-7445.Am2017-1227  0.55
2017 Dohm A, Su J, McTyre E, Soike M, Miller L, Petty W, Xing F, Lo H, Metheny-Barlow L, Watabe K, Chan M, Ruiz J, Pasche B. Determination of Tumor Gene Expression in Non–small Cell Lung Cancer Patients Who Develop Brain Metastasis Diagnosis: Analysis of a Prospective Trial International Journal of Radiation Oncology*Biology*Physics. 99: E453. DOI: 10.1016/J.Ijrobp.2017.06.1687  0.469
2016 Xing F, Liu Y, Sharma S, Wu K, Chan MD, Lo HW, Carpenter RL, Metheny-Barlow LJ, Zhou X, Qasem SA, Pasche B, Watabe K. Activation of the c-Met pathway mobilizes an inflammatory network in the brain microenvironment to promote brain metastasis of breast cancer. Cancer Research. PMID 27364556 DOI: 10.1158/0008-5472.Can-15-3541  0.511
2016 Sirkisoon SR, Carpenter RL, Rimkus T, Miller L, Metheny-Barlow L, Lo HW. EGFR and HER2 signaling in breast cancer brain metastasis. Frontiers in Bioscience (Elite Edition). 8: 245-63. PMID 26709660 DOI: 10.2741/765  0.416
2015 Choudhary M, Naczki C, Chen W, Barlow KD, Case LD, Metheny-Barlow LJ. Tumor-induced loss of mural Connexin 43 gap junction activity promotes endothelial proliferation. Bmc Cancer. 15: 427. PMID 26002762 DOI: 10.1186/S12885-015-1420-9  0.716
2015 Deng G, Metheny-Barlow L, Gallagher PE, Tallant EA. Abstract 4981: Angiotensin-(1-7) targets c-Met signaling by up-regulating the phosphatase PTP1b to reduce triple negative breast cancer Cancer Research. 75: 4981-4981. DOI: 10.1158/1538-7445.Am2015-4981  0.357
2015 Kooshki M, Naczki C, Robbins ME, Metheny-Barlow LJ. Abstract 1792: Radiation-induced downregulation of GLT-1 glutamate transporter mRNA expression is reversed by renin-angiotensin system inhibitors Cancer Research. 75: 1792-1792. DOI: 10.1158/1538-7445.Am2015-1792  0.369
2014 Greene-Schloesser D, Payne V, Peiffer AM, Hsu FC, Riddle DR, Zhao W, Chan MD, Metheny-Barlow L, Robbins ME. The peroxisomal proliferator-activated receptor (PPAR) α agonist, fenofibrate, prevents fractionated whole-brain irradiation-induced cognitive impairment. Radiation Research. 181: 33-44. PMID 24397438 DOI: 10.1667/Rr13202.1  0.326
2014 Moore ED, Kooshki M, Wheeler KT, Metheny-Barlow LJ, Robbins ME. Differential expression of Homer1a in the hippocampus and cortex likely plays a role in radiation-induced brain injury. Radiation Research. 181: 21-32. PMID 24377717 DOI: 10.1667/Rr13475.1  0.404
2013 Moore ED, Kooshki M, Metheny-Barlow LJ, Gallagher PE, Robbins ME. Angiotensin-(1-7) prevents radiation-induced inflammation in rat primary astrocytes through regulation of MAP kinase signaling. Free Radical Biology & Medicine. 65: 1060-8. PMID 24012919 DOI: 10.1016/J.Freeradbiomed.2013.08.183  0.343
2013 Vincent A, Lesser G, Brown D, Vern-Gross T, Metheny-Barlow L, Lawrence J, Chan M. Prolonged regression of metastatic leptomeningeal breast cancer that has failed conventional therapy: a case report and review of the literature. Journal of Breast Cancer. 16: 122-6. PMID 23593093 DOI: 10.4048/Jbc.2013.16.1.122  0.348
2013 Barlow KD, Sanders AM, Soker S, Ergun S, Metheny-Barlow LJ. Pericytes on the tumor vasculature: jekyll or hyde? Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 6: 1-17. PMID 22467426 DOI: 10.1007/S12307-012-0102-2  0.55
2013 Chen W, McMahan CN, Barlow KD, Juarez D, Metheny-Barlow LJ. Abstract A64: Identification of p75NTR/TrkB-BDNF axis in breast cancer brain metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A64  0.514
2012 Vern-Gross TZ, Lawrence JA, Case LD, McMullen KP, Bourland JD, Metheny-Barlow LJ, Ellis TL, Tatter SB, Shaw EG, Urbanic JJ, Chan MD. Breast cancer subtype affects patterns of failure of brain metastases after treatment with stereotactic radiosurgery. Journal of Neuro-Oncology. 110: 381-8. PMID 23001361 DOI: 10.1007/S11060-012-0976-3  0.411
2012 Buchanan CF, Szot CS, Wilson TD, Akman S, Metheny-Barlow LJ, Robertson JL, Freeman JW, Rylander MN. Cross-talk between endothelial and breast cancer cells regulates reciprocal expression of angiogenic factors in vitro. Journal of Cellular Biochemistry. 113: 1142-51. PMID 22095586 DOI: 10.1002/Jcb.23447  0.551
2012 Arter AA, Metheny-Barlow L, Gallagher PE, Tallant EA. Abstract 5224: Angiotensin-(1-7) inhibits proliferative and fibrotic signaling mechanisms in triple negative breast cancer Cancer Research. 72: 5224-5224. DOI: 10.1158/1538-7445.Am2012-5224  0.501
2012 Metheny-Barlow LJ, McMahan CN, Stadelman KM, Sanders AM, Barlow KD. Abstract 3728: Astaxanthin as an adjunct therapy for breast cancer Cancer Research. 72: 3728-3728. DOI: 10.1158/1538-7445.Am2012-3728  0.481
2011 Choudhary M, Chen W, Barlow KD, Mcmahan CN, Metheny-Barlow LJ. Abstract 1560: Breast tumor disrupt gap junction mediated vessel stabilization by two distinct mechanisms Cancer Research. 71: 1560-1560. DOI: 10.1158/1538-7445.Am2011-1560  0.723
2010 Cook KL, Metheny-Barlow LJ, Tallant EA, Gallagher PE. Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors Cancer Research. 70: 8319-8328. PMID 20837666 DOI: 10.1158/0008-5472.Can-10-1136  0.471
2010 Chen W, Olson J, McMahan CN, Choudhary M, Caldas H, Metheny-Barlow LJ. Abstract 473: Generation of a mouse model of breast cancer brain metastasis Cancer Research. 70: 473-473. DOI: 10.1158/1538-7445.Am10-473  0.705
2010 Choudhary M, Chen W, Naczki-McMahan C, Barlow KD, Metheny-Barlow LJ. Abstract 3430: Breast tumor cells inhibit vascular gap junction communication by downregulation of mural cell Connexin 43 Cancer Research. 70: 3430-3430. DOI: 10.1158/1538-7445.Am10-3430  0.731
2006 Metheny-Barlow LJ, Li LY. Vascular endothelial growth inhibitor (VEGI), an endogenous negative regulator of angiogenesis. Seminars in Ophthalmology. 21: 49-58. PMID 16517446 DOI: 10.1080/08820530500511446  0.466
2005 Ramljak D, Romanczyk LJ, Metheny-Barlow LJ, Thompson N, Knezevic V, Galperin M, Ramesh A, Dickson RB. Pentameric procyanidin from Theobroma cacao selectively inhibits growth of human breast cancer cells. Molecular Cancer Therapeutics. 4: 537-46. PMID 15827326 DOI: 10.1158/1535-7163.Mct-04-0286  0.499
2004 Metheny-Barlow LJ, Tian S, Hayes AJ, Li LY. Direct chemotactic action of angiopoietin-1 on mesenchymal cells in the presence of VEGF. Microvascular Research. 68: 221-30. PMID 15501241 DOI: 10.1016/J.Mvr.2004.08.005  0.479
2003 Metheny-Barlow LJ, Li LY. The enigmatic role of angiopoietin-1 in tumor angiogenesis. Cell Research. 13: 309-17. PMID 14672554 DOI: 10.1038/Sj.Cr.7290176  0.537
2002 Tian S, Hayes AJ, Metheny-Barlow LJ, Li LY. Stabilization of breast cancer xenograft tumour neovasculature by angiopoietin-1. British Journal of Cancer. 86: 645-51. PMID 11870550 DOI: 10.1038/sj.bjc.6600082  0.402
2001 Yu J, Tian S, Metheny-Barlow L, Chew L, Hayes AJ, Pan H, Yu G, Li L. Modulation of Endothelial Cell Growth Arrest and Apoptosis by Vascular Endothelial Growth Inhibitor Circulation Research. 89: 1161-1167. PMID 11739281 DOI: 10.1161/Hh2401.101909  0.443
2001 Metheny-Barlow LJ, Flynn B, Gijssel HEv, Marrogi A, Gerwin BI. Paradoxical effects of platelet-derived growth factor-A overexpression in malignant mesothelioma. Antiproliferative effects in vitro and tumorigenic stimulation in vivo. American Journal of Respiratory Cell and Molecular Biology. 24: 694-702. PMID 11415934 DOI: 10.1165/Ajrcmb.24.6.4334  0.352
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