Carrie L. Lucas, Ph.D. - Publications

Affiliations: 
2010 Harvard University, Cambridge, MA, United States 
Area:
Immunology, Cell Biology

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Axisa PP, Yoshida TM, Lucca LE, Kasler HG, Lincoln MR, Pham GH, Del Priore D, Carpier JM, Lucas CL, Verdin E, Sumida TS, Hafler DA. A multiple sclerosis-protective coding variant reveals an essential role for HDAC7 in regulatory T cells. Science Translational Medicine. 14: eabl3651. PMID 36516268 DOI: 10.1126/scitranslmed.abl3651  0.316
2020 Reed JC, Preston-Hurlburt P, Philbrick W, Betancur G, Korah M, Lucas C, Herold KC. The receptor for advanced glycation endproducts (RAGE) modulates T cell signaling. Plos One. 15: e0236921. PMID 32986722 DOI: 10.1371/journal.pone.0236921  0.424
2019 Takeda AJ, Maher TJ, Zhang Y, Lanahan SM, Bucklin ML, Compton SR, Tyler PM, Comrie WA, Matsuda M, Olivier KN, Pittaluga S, McElwee JJ, Long Priel DA, Kuhns DB, Williams RL, ... ... Lucas CL, et al. Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology. Nature Communications. 10: 4364. PMID 31554793 DOI: 10.1038/S41467-019-12311-5  0.447
2017 Carpier JM, Lucas CL. Epstein-Barr Virus Susceptibility in Activated PI3Kδ Syndrome (APDS) Immunodeficiency. Frontiers in Immunology. 8: 2005. PMID 29387064 DOI: 10.3389/Fimmu.2017.02005  0.363
2017 Rao VK, Webster S, Dalm VASH, Šedivá A, van Hagen PM, Holland S, Rosenzweig SD, Christ AD, Sloth B, Cabanski M, Joshi AD, de Buck S, Doucet J, Guerini D, Kalis C, ... ... Lucas CL, et al. Effective 'Activated PI3Kδ Syndrome'-targeted therapy with the PI3Kδ inhibitor leniolisib. Blood. PMID 28972011 DOI: 10.1182/Blood-2017-08-801191  0.491
2016 Lucas CL, Chandra A, Nejentsev S, Condliffe AM, Okkenhaug K. PI3Kδ and primary immunodeficiencies. Nature Reviews. Immunology. PMID 27616589 DOI: 10.1038/Nri.2016.93  0.337
2016 Elkaim E, Neven B, Bruneau J, Mitsui-Sekinaka K, Stanislas A, Heurtier L, Lucas CL, Matthews H, Deau MC, Sharapova S, Curtis J, Reichenbach J, Glastre C, Parry DA, Arumugakani G, et al. Clinical and immunologic phenotype associated with activated phosphoinositide 3-kinase δ syndrome 2: A cohort study. The Journal of Allergy and Clinical Immunology. PMID 27221134 DOI: 10.1016/J.Jaci.2016.03.022  0.323
2014 Lucas CL, Zhang Y, Venida A, Wang Y, Hughes J, McElwee J, Butrick M, Matthews H, Price S, Biancalana M, Wang X, Richards M, Pozos T, Barlan I, Ozen A, et al. Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K. The Journal of Experimental Medicine. 211: 2537-47. PMID 25488983 DOI: 10.1084/Jem.20141759  0.427
2014 Haspot F, Li HW, Lucas CL, Fehr T, Beyaz S, Sykes M. Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 49-58. PMID 24304495 DOI: 10.1111/Ajt.12525  0.66
2014 Lucas CL, Kuehn HS, Zhao F, Niemela JE, Deenick EK, Palendira U, Avery DT, Moens L, Cannons JL, Biancalana M, Stoddard J, Ouyang W, Frucht DM, Rao VK, Atkinson TP, et al. Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency. Nature Immunology. 15: 88-97. PMID 24165795 DOI: 10.1038/Ni.2771  0.413
2013 Chaigne-Delalande B, Li FY, O'Connor GM, Lukacs MJ, Jiang P, Zheng L, Shatzer A, Biancalana M, Pittaluga S, Matthews HF, Jancel TJ, Bleesing JJ, Marsh RA, Kuijpers TW, Nichols KE, ... Lucas CL, et al. Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D. Science (New York, N.Y.). 341: 186-91. PMID 23846901 DOI: 10.1126/Science.1240094  0.442
2011 Lucas CL, Sykes M. Layers of regulation in induction of mixed chimerism by anti-CD40L. Chimerism. 2: 111-3. PMID 22509427 DOI: 10.4161/Chim.2.4.19053  0.554
2011 Lucas CL, Workman CJ, Beyaz S, LoCascio S, Zhao G, Vignali DA, Sykes M. LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L. Blood. 117: 5532-40. PMID 21422469 DOI: 10.1182/Blood-2010-11-318675  0.647
2011 Hermanrud CE, Lucas CL, Sykes M, Huang CA, Wang Z. Expression and purification of soluble murine CD40L monomers and polymers in yeast Pichia pastoris. Protein Expression and Purification. 76: 115-20. PMID 21074618 DOI: 10.1016/J.Pep.2010.11.006  0.483
2010 Mollov JL, Lucas CL, Haspot F, Kurtz J, Gaspar C, Guzman A, Sykes M. Recipient dendritic cells, but not B cells, are required antigen-presenting cells for peripheral alloreactive CD8+ T-cell tolerance. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10: 518-26. PMID 20121730 DOI: 10.1111/J.1600-6143.2009.02967.X  0.66
2010 Fehr T, Lucas CL, Kurtz J, Onoe T, Zhao G, Hogan T, Vallot C, Rao A, Sykes M. A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo. Blood. 115: 1280-7. PMID 20007805 DOI: 10.1182/Blood-2009-07-230680  0.659
2010 del Rio ML, Lucas CL, Buhler L, Rayat G, Rodriguez-Barbosa JI. HVEM/LIGHT/BTLA/CD160 cosignaling pathways as targets for immune regulation. Journal of Leukocyte Biology. 87: 223-35. PMID 20007250 DOI: 10.1189/jlb.0809590  0.366
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