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Guocan Wang, Ph.D. - Publications

Affiliations: 
2011 Weill Cornell Medical College, New York, NY, United States 
Area:
Oncology, Molecular Biology, Cell Biology
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lee YC, Lin SC, Yu G, Zhu M, Song JH, Rivera K, Pappin DJ, Logothetis CJ, Panaretakis T, Wang G, Yu-Lee LY, Lin SH. Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition. Oncogene. PMID 34845375 DOI: 10.1038/s41388-021-02131-7  0.302
2021 Zhu M, Peng R, Liang X, Lan Z, Tang M, Hou P, Song JH, Mak CSL, Park J, Zheng SE, Huang A, Ma X, Chen R, Chang Q, Logothetis CJ, ... ... Wang G, et al. P4HA2-induced prolyl hydroxylation suppresses YAP1-mediated prostate cancer cell migration, invasion, and metastasis. Oncogene. PMID 34471235 DOI: 10.1038/s41388-021-02000-3  0.379
2021 Yu G, Shen P, Lee YC, Pan J, Song JH, Pan T, Lin SC, Liang X, Wang G, Panaretakis T, Logothetis CJ, Gallick GE, Yu-Lee LY, Lin SH. Multiple pathways coordinating reprogramming of endothelial cells into osteoblasts by BMP4. Iscience. 24: 102388. PMID 33981975 DOI: 10.1016/j.isci.2021.102388  0.331
2020 Lunardi A, Ala U, Epping MT, Salmena L, Clohessy JG, Webster KA, Wang G, Mazzucchelli R, Bianconi M, Stack EC, Lis R, Patnaik A, Cantley LC, Bubley G, Cordon-Cardo C, et al. Author Correction: A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer. Nature Genetics. PMID 32884149 DOI: 10.1038/S41588-020-0701-7  0.509
2020 Zhao D, Cai L, Lu X, Liang X, Li J, Chen P, Ittmann M, Shang X, Jiang S, Li H, Meng C, Flores I, Song JH, Horner JW, Lan Z, ... ... Wang G, et al. Chromatin Regulator, CHD1, Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer. Cancer Discovery. PMID 32385075 DOI: 10.1158/2159-8290.Cd-19-1352  0.5
2020 Corn PG, Zhang M, Nogueras-Gonzalez GM, Xiao L, Zurita AJ, Subudhi SK, Tu SM, Aparicio AM, Coarfa C, Rajapakshe K, Huang S, Navone NM, Lin SH, Wang G, Ramachandran S, et al. A Phase II Study of Cabozantinib and Androgen Ablation in Patients with Hormone-Naïve Metastatic Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31941830 DOI: 10.1158/1078-0432.Ccr-19-2389  0.391
2020 Liao W, Overman MJ, Boutin A, Dey P, Zhao D, Wang G, Li J, Lan Z, Li J, Shang X, Tang M, Jiang S, Ma X, Chen P, Katkhuda R, et al. Abstract IA27: Context-dependent role of KRAS in GI malignancies Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Ras18-Ia27  0.44
2020 Wang G, Lu X, Chakravarti D, Kapoor A, Yao W, Ying H, Dey P, Wu C, Spring D, Hou P, Deng P, Zhao D, Hu B, Xizeng M, Logothesis C, et al. Abstract IA24: YAP in cancer and inflammation Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-Ia24  0.407
2019 Su W, Han HH, Wang Y, Zhang B, Zhou B, Cheng Y, Rumandla A, Gurrapu S, Chakraborty G, Su J, Yang G, Liang X, Wang G, Rosen N, Scher HI, et al. The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression. Cancer Cell. PMID 31327655 DOI: 10.1016/J.Ccell.2019.06.009  0.433
2019 Liao W, Overman MJ, Boutin AT, Shang X, Zhao D, Dey P, Li J, Wang G, Lan Z, Li J, Tang M, Jiang S, Ma X, Chen P, Katkhuda R, et al. KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer. Cancer Cell. PMID 30905761 DOI: 10.1016/J.Ccell.2019.02.008  0.366
2019 Chakravarti D, Multani A, Dey P, Hu B, Zhao D, Chang K, Xizeng M, Wang G, Terranova C, Liao W, Spring D, Hou P, Zhang J, Okhuysen P, Vilar E, et al. Abstract LB-290: Telomere dysfunction is a driver of inflammatory bowel disease Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-290  0.308
2019 Jayaprakash P, Ai M, Liu A, Budhani P, Bartkowiak T, Sheng J, Ager C, Nicholas C, Jaiswal A, Sun Y, Shah K, Balasubramanyam S, Li N, Wang G, Ning J, et al. Abstract 5011: Targeting hypoxia-induced immune suppression to overcome immunotherapy resistance in prostate cancer Cancer Research. 79: 5011-5011. DOI: 10.1158/1538-7445.Am2019-5011  0.464
2018 Jayaprakash P, Ai M, Liu A, Budhani P, Bartkowiak T, Sheng J, Ager CR, Nicholas C, Jaiswal AR, Sun Y, Shah K, Balasubramanyam S, Li N, Wang G, Ning J, et al. Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy. The Journal of Clinical Investigation. PMID 30188869 DOI: 10.1172/Jci96268  0.368
2018 Wang G, Zhao D, Spring DJ, DePinho RA. Genetics and biology of prostate cancer. Genes & Development. 32: 1105-1140. PMID 30181359 DOI: 10.1101/Gad.315739.118  0.45
2018 Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, ... ... Wang G, et al. Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Cancer Cell. 33: 152. PMID 29316430 DOI: 10.1016/J.Ccell.2017.12.012  0.315
2018 Bezzi M, Seitzer N, Ishikawa T, Reschke M, Chen M, Wang G, Mitchell C, Ng C, Katon J, Lunardi A, Signoretti S, Clohessy JG, Zhang J, Pandolfi PP. Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms. Nature Medicine. PMID 29309058 DOI: 10.1038/Nm.4463  0.55
2017 Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, ... ... Wang G, et al. Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Cancer Cell. 32: 42-56.e6. PMID 28697342 DOI: 10.1016/J.Ccell.2017.06.003  0.358
2017 Zhao D, Lu X, Wang G, Lan Z, Liao W, Li J, Liang X, Chen JR, Shah S, Shang X, Tang M, Deng P, Dey P, Chakravarti D, Chen P, et al. Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer. Nature. PMID 28166537 DOI: 10.1038/Nature21357  0.448
2017 Wang Q, Hu B, Hu X, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel FP, Cho HJ, Lin Y, Satani N, Martinez-Ledesma E, Zheng S, ... ... Wang G, et al. TMIC-22. DECIPHERING GLIOMA INTRINSIC TRANSCRIPTIONAL SUBTYPES IDENTIFIES TUMOR EVOLUTION ASSOCIATES WITH CHANGES IN IMMUNE-MICROENVIRONMENT Neuro-Oncology. 19: vi247-vi248. DOI: 10.1093/Neuonc/Nox168.1011  0.342
2016 Hu B, Wang Q, Wang YA, Hua S, Sauvé CG, Ong D, Lan ZD, Chang Q, Ho YW, Monasterio MM, Lu X, Zhong Y, Zhang J, Deng P, Tan Z, ... Wang G, et al. Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth. Cell. 167: 1281-1295.e18. PMID 27863244 DOI: 10.1016/J.Cell.2016.10.039  0.355
2015 Wang G, Lu X, Dey P, Deng P, Wu CC, Jiang S, Fang Z, Zhao K, Konaparthi R, Hua S, Zhang J, Li-Ning-Tapia EM, Kapoor A, Wu CJ, Patel NB, et al. Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression. Cancer Discovery. PMID 26701088 DOI: 10.1186/2051-1426-3-S2-P421  0.497
2015 Liu XS, Chandramouly G, Rass E, Guan Y, Wang G, Hobbs RM, Rajendran A, Xie A, Shah JV, Davis AJ, Scully R, Lunardi A, Pandolfi PP. LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair. Nature Communications. 6: 8325. PMID 26446488 DOI: 10.1038/Ncomms9325  0.484
2015 Guarnerio J, Riccardi L, Taulli R, Maeda T, Wang G, Hobbs RM, Song MS, Sportoletti P, Bernardi R, Bronson RT, Castillo-Martin M, Cordon-Cardo C, Lunardi A, Pandolfi PP. A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells. Cancer Discovery. 5: 396-409. PMID 25614485 DOI: 10.1158/2159-8290.Cd-14-1022  0.433
2014 Watson IR, Li L, Cabeceiras PK, Mahdavi M, Gutschner T, Genovese G, Wang G, Fang Z, Tepper JM, Stemke-Hale K, Tsai KY, Davies MA, Mills GB, Chin L. The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF. Cancer Research. 74: 4845-52. PMID 25056119 DOI: 10.1158/0008-5472.Can-14-1232-T  0.341
2013 Wang G, Lunardi A, Zhang J, Chen Z, Ala U, Webster KA, Tay Y, Gonzalez-Billalabeitia E, Egia A, Shaffer DR, Carver B, Liu XS, Taulli R, Kuo WP, Nardella C, et al. Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion. Nature Genetics. 45: 739-46. PMID 23727861 DOI: 10.1038/Ng.2654  0.578
2013 Lunardi A, Ala U, Epping MT, Salmena L, Clohessy JG, Webster KA, Wang G, Mazzucchelli R, Bianconi M, Stack EC, Lis R, Patnaik A, Cantley LC, Bubley G, Cordon-Cardo C, et al. A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer. Nature Genetics. 45: 747-55. PMID 23727860 DOI: 10.1038/Ng.2650  0.551
2013 Lunardi A, Guarnerio J, Wang G, Maeda T, Pandolfi PP. Role of LRF/Pokemon in lineage fate decisions. Blood. 121: 2845-53. PMID 23396304 DOI: 10.1182/Blood-2012-11-292037  0.382
2012 Wang G, Gao Y, Li L, Jin G, Cai Z, Chao JI, Lin HK. K63-linked ubiquitination in kinase activation and cancer. Frontiers in Oncology. 2: 5. PMID 22649774 DOI: 10.3389/Fonc.2012.00005  0.406
2012 Wang G, Wang Z, Sarkar FH, Wei W. Targeting prostate cancer stem cells for cancer therapy. Discovery Medicine. 13: 135-42. PMID 22369972  0.335
2012 Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A, Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, et al. Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases. Cell. 148: 896-907. PMID 22341455 DOI: 10.1016/J.Cell.2012.01.039  0.47
2012 Wang G, Chan CH, Gao Y, Lin HK. Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis. Chinese Journal of Cancer. 31: 169-77. PMID 22200179 DOI: 10.5732/Cjc.011.10319  0.425
2010 Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. Nature. 464: 374-9. PMID 20237562 DOI: 10.1038/Nature08815  0.531
2010 Lin H, Chen Z, Wang G, Nardella C, Lee S, Chan C, Yang W, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Erratum: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence Nature. 466: 398-398. DOI: 10.1038/Nature09280  0.469
2009 Maeda T, Ito K, Merghoub T, Poliseno L, Hobbs RM, Wang G, Dong L, Maeda M, Dore LC, Zelent A, Luzzatto L, Teruya-Feldstein J, Weiss MJ, Pandolfi PP. LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis. Developmental Cell. 17: 527-40. PMID 19853566 DOI: 10.1016/J.Devcel.2009.09.005  0.493
2009 Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, Yang WL, Erdjument-Bromage H, Nakayama KI, Nimer S, Tempst P, Pandolfi PP. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nature Cell Biology. 11: 420-32. PMID 19270694 DOI: 10.1038/Ncb1849  0.484
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