Year |
Citation |
Score |
2024 |
Dowrey TW, Cranston SF, Skvir N, Lok Y, Gould B, Petrowitz B, Villar D, Shan J, James M, Dodge M, Belkina AC, Giadone RM, Sebastiani P, Perls TT, Andersen SL, ... Murphy GJ, et al. A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring. Biorxiv : the Preprint Server For Biology. PMID 38559230 DOI: 10.1101/2024.03.12.584663 |
0.421 |
|
2023 |
Hoffman SE, Dowrey TW, Villacorta Martin C, Bi K, Titchen B, Johri S, DelloStritto L, Patel M, Mackichan C, Inga S, Chen J, Grimaldi G, Napolitano S, Wakiro I, Wu J, ... ... Murphy GJ, et al. Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors. Science Advances. 9: eadd9668. PMID 37756410 DOI: 10.1126/sciadv.add9668 |
0.319 |
|
2023 |
Yeung AK, Villacorta-Martin C, Lindstrom-Vautrin J, Belkina AC, Vanuytsel K, Dowrey TW, Ysasi AB, Bawa P, Wang F, Vrbanac V, Mostoslavsky G, Balazs A, Murphy GJ. De-novo hematopoiesis from the fetal lung. Blood Advances. PMID 37729429 DOI: 10.1182/bloodadvances.2022008347 |
0.348 |
|
2022 |
Heinze D, Park S, McCracken A, Haratianfar M, Lindstrom J, Villacorta-Martin C, Mithal A, Wang F, Yang MW, Murphy G, Mostoslavsky G. Notch activation during early mesoderm induction modulates emergence of the T/NK cell lineage from human iPSCs. Stem Cell Reports. PMID 36332629 DOI: 10.1016/j.stemcr.2022.10.007 |
0.477 |
|
2022 |
Vanuytsel K, Yeung AK, Dowrey TW, Murphy GJ, Belkina AC. Comprehensive phenotyping of hematopoietic stem and progenitor cells in the human fetal liver. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 35253987 DOI: 10.1002/cyto.a.24540 |
0.547 |
|
2022 |
Vanuytsel K, Villacorta-Martin C, Lindstrom-Vautrin J, Wang Z, Garcia-Beltran WF, Vrbanac V, Parsons D, Lam EC, Matte TM, Dowrey TW, Kumar SS, Li M, Wang F, Yeung AK, Mostoslavsky G, ... ... Murphy GJ, et al. Multi-modal profiling of human fetal liver hematopoietic stem cells reveals the molecular signature of engraftment. Nature Communications. 13: 1103. PMID 35232959 DOI: 10.1038/s41467-022-28616-x |
0.544 |
|
2022 |
Sun Y, Habara A, Le CQ, Nguyen N, Chen R, Murphy GJ, Chui DHK, Steinberg MH, Cui S. Pharmacologic induction of PGC-1α stimulates fetal haemoglobin gene expression. British Journal of Haematology. PMID 35118652 DOI: 10.1111/bjh.18042 |
0.411 |
|
2021 |
Blakemore D, Vilaplana-Lopera N, Almaghrabi R, Gonzalez E, Moya M, Ward C, Murphy G, Gambus A, Petermann E, Stewart GS, García P. MYBL2 and ATM suppress replication stress in pluripotent stem cells. Embo Reports. e51120. PMID 33779025 DOI: 10.15252/embr.202051120 |
0.307 |
|
2020 |
Giadone RM, Liberti DC, Matte TM, Rosarda JD, Torres-Arancivia C, Ghosh S, Diedrich JK, Pankow S, Skvir N, Jean JC, Yates JR, Wilson AA, Connors LH, Kotton DN, Wiseman RL, ... Murphy GJ, et al. Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease. Stem Cell Reports. PMID 32735824 DOI: 10.1016/J.Stemcr.2020.07.003 |
0.541 |
|
2020 |
Kanchan K, Iyer K, Yanek LR, Carcamo-Orive I, Taub MA, Malley C, Baldwin K, Becker LC, Broeckel U, Cheng L, Cowan C, D'Antonio M, Frazer KA, Quertermous T, Mostoslavsky G, ... Murphy G, et al. Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program. Stem Cell Research. 46: 101803. PMID 32442913 DOI: 10.1016/J.Scr.2020.101803 |
0.315 |
|
2019 |
Steinberg MH, Kumar S, Murphy GJ, Vanuytsel K. Sickle cell disease in the era of precision medicine: looking to the future. Expert Review of Precision Medicine and Drug Development. 4: 357-367. PMID 33015364 DOI: 10.1080/23808993.2019.1688658 |
0.432 |
|
2019 |
Le CQ, Myers G, Habara A, Jearawiriyapaisarn N, Murphy GJ, Chui DHK, Steinberg M, Engel JD, Cui S. Inhibition of LSD1 by small molecule inhibitors stimulates fetal hemoglobin synthesis. Blood. PMID 30992270 DOI: 10.1182/Blood.2018892737 |
0.391 |
|
2019 |
Athwal HK, Murphy G, Tibbs E, Cornett A, Hill E, Yeoh K, Berenstein E, Hoffman MP, Lombaert IMA. Sox10 Regulates Plasticity of Epithelial Progenitors toward Secretory Units of Exocrine Glands. Stem Cell Reports. PMID 30713042 DOI: 10.1016/j.stemcr.2019.01.002 |
0.405 |
|
2019 |
Vanuytsel K, Villacorta-Martin C, Garcia Beltran W, Matte T, Balazs A, Murphy GJ. Transcriptional, Protein-Level and Functional Profiling of Human Fetal Liver-Derived Hematopoietic Stem Cells at Single Cell Resolution Blood. 134: 1187-1187. DOI: 10.1182/Blood-2019-126857 |
0.501 |
|
2018 |
Seo H, Chen SJ, Hashimoto K, Endo H, Nishi Y, Ohta A, Yamamoto T, Hotta A, Sawaguchi A, Hayashi H, Koseki N, Murphy GJ, Fukuda K, Sugimoto N, Eto K. A β1-tubulin-based megakaryocyte maturation reporter system identifies novel drugs that promote platelet production. Blood Advances. 2: 2262-2272. PMID 30206099 DOI: 10.1182/Bloodadvances.2018019547 |
0.373 |
|
2018 |
Vanuytsel K, Matte T, Leung A, Naing ZH, Morrison T, Chui DHK, Steinberg MH, Murphy GJ. Induced pluripotent stem cell-based mapping of β-globin expression throughout human erythropoietic development. Blood Advances. 2: 1998-2011. PMID 30108108 DOI: 10.1182/Bloodadvances.2018020560 |
0.592 |
|
2018 |
Giadone RM, Rosarda JD, Akepati PR, Thomas AC, Boldbaatar B, James MF, Wilson AA, Sanchorawala V, Connors LH, Berk JL, Wiseman RL, Murphy GJ. A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-8. PMID 30032658 DOI: 10.1080/13506129.2018.1489228 |
0.538 |
|
2018 |
Leung A, Zulick E, Skvir N, Vanuytsel K, Morrison TA, Naing ZH, Wang Z, Dai Y, Chui DHK, Steinberg MH, Sherr DH, Murphy GJ. Notch and AHR signaling impact definitive hematopoiesis from human pluripotent stem cells. Stem Cells (Dayton, Ohio). PMID 29569827 DOI: 10.1002/Stem.2822 |
0.659 |
|
2018 |
Habara A, Le C, Murphy GJ, Chui DHK, Steinberg MH, Cui S. Regulating Transcriptional Co-Activator PGC-1α for the Treatment of Sickle Cell Disease Blood. 132: 2358-2358. DOI: 10.1182/Blood-2018-99-111022 |
0.403 |
|
2017 |
Morrison TA, Wilcox I, Luo HY, Farrell JJ, Kurita R, Nakamura Y, Murphy GJ, Cui S, Steinberg MH, Chui DHK. A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression. Blood Cells, Molecules & Diseases. 69: 1-9. PMID 29227829 DOI: 10.1016/j.bcmd.2017.11.003 |
0.436 |
|
2017 |
Shaikho EM, Farrell JJ, Alsultan A, Qutub H, Al-Ali AK, Figueiredo MS, Chui DHK, Farrer LA, Murphy GJ, Mostoslavsky G, Sebastiani P, Steinberg MH. A phased SNP-based classification of sickle cell anemia HBB haplotypes. Bmc Genomics. 18: 608. PMID 28800727 DOI: 10.1186/S12864-017-4013-Y |
0.351 |
|
2017 |
Park S, Gianotti-Sommer A, Molina-Estevez FJ, Vanuytsel K, Skvir N, Leung A, Rozelle SS, Shaikho EM, Weir I, Jiang Z, Luo HY, Chui DH, Figueiredo MS, Alsultan A, Al-Ali A, ... ... Murphy GJ, et al. A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells. Stem Cell Reports. PMID 28111279 DOI: 10.1016/J.Stemcr.2016.12.017 |
0.76 |
|
2016 |
Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, ... ... Murphy G, et al. A Candidate Trans-acting Modulator of Fetal Hemoglobin Gene Expression in the Arab-Indian Haplotype of Sickle Cell Anemia: -ANTXR1 Variants and HbF. American Journal of Hematology. PMID 27501013 DOI: 10.1002/Ajh.24527 |
0.519 |
|
2016 |
Smith BW, Stanford EA, Sherr DH, Murphy GJ. Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development. Stem Cells International. 2016: 2574152. PMID 27148368 DOI: 10.1155/2016/2574152 |
0.495 |
|
2016 |
Tirosh I, Izar B, Prakadan SM, Wadsworth MH, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, et al. Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq. Science (New York, N.Y.). 352: 189-196. PMID 27124452 DOI: 10.1126/Science.Aad0501 |
0.392 |
|
2016 |
Stanford EA, Wang Z, Novikov O, Mulas F, Landesman-Bollag E, Monti S, Smith BW, Seldin DC, Murphy GJ, Sherr DH. The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells. Bmc Biology. 14: 20. PMID 26984638 DOI: 10.1186/S12915-016-0240-Y |
0.524 |
|
2016 |
Thomas DD, Sommer AG, Balazs AB, Beerman I, Murphy GJ, Rossi D, Mostoslavsky G. Insulin-like growth factor 2 (IGF2) modulates murine hematopoietic stem cell maintenance through upregulation of p57. Experimental Hematology. PMID 26872540 DOI: 10.1016/J.Exphem.2016.01.010 |
0.468 |
|
2016 |
Stanford E, Wang Z, Novikov O, Ramirez-Cardenas A, Mulas F, Landesman-Bollag E, Monti S, Smith B, Bais M, Kukuruzinska M, Murphy G, Sherr D. A role for the aryl hydrocarbon receptor (Ahr) in the production and function of breast and oral cancer stem-like cells and the potential therapeutic value of Ahr modulators Toxicology Letters. 259: S20. DOI: 10.1016/j.toxlet.2016.07.090 |
0.322 |
|
2015 |
Wilson AA, Ying L, Liesa M, Segeritz CP, Mills JA, Shen SS, Jean J, Lonza GC, Liberti DC, Lang AH, Nazaire J, Gower AC, Müeller FJ, Mehta P, Ordóñez A, ... ... Murphy GJ, et al. Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells. Stem Cell Reports. 4: 873-85. PMID 25843048 DOI: 10.1016/J.Stemcr.2015.02.021 |
0.566 |
|
2015 |
Leung A, Murphy GJ. Multisystemic Disease Modeling of Liver-Derived Protein Folding Disorders Using Induced Pluripotent Stem Cells (iPSCs). Methods in Molecular Biology (Clifton, N.J.). PMID 25646614 DOI: 10.1007/7651_2014_194 |
0.447 |
|
2015 |
Vathipadiekal V, Farrell J, Shuai Z, Edward H, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Simkin I, Farrer L, Jiang Z, Luo HY, Huang S, Mostoslavsky G, ... Murphy GJ, et al. A Candidate Trans-Acting Modulator of Fetal Hemoglobin Gene Expression in the Arab-Indian Haplotype of Sickle Cell Anemia Blood. 126: 409-409. DOI: 10.1182/Blood.V126.23.409.409 |
0.355 |
|
2015 |
Park S, Gianotti-Sommer A, Chui DHK, Figueiredo MS, Alsultan A, Al-Ali A, Steinberg MH, Murphy GJ, Mostoslavsky G. A Library of Sickle Cell Anemia Induced Pluripotent Stem Cells of Diverse Haplotypes and Ethnicities Blood. 126: 2354-2354. DOI: 10.1182/Blood.V126.23.2354.2354 |
0.638 |
|
2014 |
Smith BW, Murphy GJ. Stem cells, megakaryocytes, and platelets. Current Opinion in Hematology. 21: 430-7. PMID 25023469 DOI: 10.1097/Moh.0000000000000064 |
0.491 |
|
2014 |
Wang LB, Sommer AG, Leung A, Park S, Chui DHK, Steinberg MH, Mostoslavsky G, Murphy GJ. Multisystem, Induced Pluripotent Stem Cell (iPSC) Modeling Reveals a Role for Growth Differentiation Factors (GDFs) in the Etiology of β Thalassemia and Ineffective Erythropoiesis Blood. 124: 4039-4039. DOI: 10.1182/Blood.V124.21.4039.4039 |
0.486 |
|
2013 |
Leung A, Nah SK, Reid W, Ebata A, Koch CM, Monti S, Genereux JC, Wiseman RL, Wolozin B, Connors LH, Berk JL, Seldin DC, Mostoslavsky G, Kotton DN, Murphy GJ. Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis. Stem Cell Reports. 1: 451-63. PMID 24286032 DOI: 10.1016/J.Stemcr.2013.10.003 |
0.506 |
|
2013 |
Smith BW, Rozelle SS, Leung A, Ubellacker J, Parks A, Nah SK, French D, Gadue P, Monti S, Chui DH, Steinberg MH, Frelinger AL, Michelson AD, Theberge R, McComb ME, ... ... Murphy GJ, et al. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. Blood. 122: 376-85. PMID 23723449 DOI: 10.1182/Blood-2012-11-466722 |
0.78 |
|
2012 |
Sommer AG, Rozelle SS, Sullivan S, Mills JA, Park SM, Smith BW, Iyer AM, French DL, Kotton DN, Gadue P, Murphy GJ, Mostoslavsky G. Generation of human induced pluripotent stem cells from peripheral blood using the STEMCCA lentiviral vector. Journal of Visualized Experiments : Jove. PMID 23149977 DOI: 10.3791/4327 |
0.769 |
|
2012 |
Smith BW, Rozelle SS, Gadue P, French DL, Chui DHK, Steinberg MH, Sherr DH, Murphy GJ. The Aryl Hydrocarbon Receptor (AhR) Regulates the Production of Bipotential Hematopoietic Progenitor Cells Blood. 120: 766-766. DOI: 10.1182/Blood.V120.21.766.766 |
0.777 |
|
2012 |
Rozelle SS, Smith BW, Melista E, Aneni E, Sebastiani P, Baldwin CT, Alsultan A, Chui DHK, Mostoslavsky G, Steinberg MH, Murphy GJ. Induced Pluripotent Stem Cell Modeling of Sickle Cell Anemia Blood. 120: 3233-3233. DOI: 10.1182/Blood.V120.21.3233.3233 |
0.783 |
|
2011 |
Christodoulou C, Longmire TA, Shen SS, Bourdon A, Sommer CA, Gadue P, Spira A, Gouon-Evans V, Murphy GJ, Mostoslavsky G, Kotton DN. Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes. The Journal of Clinical Investigation. 121: 2313-25. PMID 21537085 DOI: 10.1172/Jci43853 |
0.646 |
|
2011 |
Purwar R, Campbell J, Murphy G, Richards WG, Clark RA, Kupper TS. Resident memory T cells (T(RM)) are abundant in human lung: diversity, function, and antigen specificity. Plos One. 6: e16245. PMID 21298112 DOI: 10.1371/Journal.Pone.0016245 |
0.335 |
|
2011 |
Smith BW, Kotton DN, Mostoslavsky G, Murphy GJ. Pluripotent Stem Cell Modeling of Normal and Abnormal Megakaryocyte Development and Platelet Production Blood. 118: 1276-1276. DOI: 10.1182/Blood.V118.21.1276.1276 |
0.567 |
|
2010 |
Somers A, Jean JC, Sommer CA, Omari A, Ford CC, Mills JA, Ying L, Sommer AG, Jean JM, Smith BW, Lafyatis R, Demierre MF, Weiss DJ, French DL, Gadue P, ... Murphy GJ, et al. Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette. Stem Cells (Dayton, Ohio). 28: 1728-40. PMID 20715179 DOI: 10.1002/Stem.495 |
0.595 |
|
2010 |
Wilson AA, Murphy GJ, Hamakawa H, Kwok LW, Srinivasan S, Hovav AH, Mulligan RC, Amar S, Suki B, Kotton DN. Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages. The Journal of Clinical Investigation. 120: 379-89. PMID 20038801 DOI: 10.1172/Jci36666 |
0.466 |
|
2010 |
Sommer CA, Sommer AG, Longmire TA, Christodoulou C, Thomas DD, Gostissa M, Alt FW, Murphy GJ, Kotton DN, Mostoslavsky G. Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector. Stem Cells (Dayton, Ohio). 28: 64-74. PMID 19904830 DOI: 10.1002/Stem.255 |
0.607 |
|
2009 |
Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, Mostoslavsky G. Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells (Dayton, Ohio). 27: 543-9. PMID 19096035 DOI: 10.1634/Stemcells.2008-1075 |
0.642 |
|
2007 |
Alison MR, Murphy G, Leedham S. Stem cells and cancer: a deadly mix. Cell and Tissue Research. 331: 109-24. PMID 17938965 DOI: 10.1007/s00441-007-0510-7 |
0.495 |
|
2006 |
Murphy GJ, Mostoslavsky G, Kotton DN, Mulligan RC. Exogenous control of mammalian gene expression via modulation of translational termination. Nature Medicine. 12: 1093-9. PMID 16892063 DOI: 10.1038/Nm1376 |
0.404 |
|
2004 |
Gaur M, Murphy GJ, Frampton J, Leavitt AD. Using retroviruses to express genes in primary megakaryocyte lineage cells. Methods in Molecular Biology (Clifton, N.J.). 273: 381-96. PMID 15308813 DOI: 10.1385/1-59259-783-1:381 |
0.478 |
|
2004 |
Emambokus NR, Murphy GJ, Frampton J. Manipulation of gene expression in megakaryocytes. Methods in Molecular Biology (Clifton, N.J.). 273: 33-56. PMID 15308792 DOI: 10.1385/1-59259-783-1:033 |
0.506 |
|
2004 |
Göttgens B, Broccardo C, Sanchez MJ, Deveaux S, Murphy G, Göthert JR, Kotsopoulou E, Kinston S, Delaney L, Piltz S, Barton LM, Knezevic K, Erber WN, Begley CG, Frampton J, et al. The scl +18/19 stem cell enhancer is not required for hematopoiesis: identification of a 5' bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1. Molecular and Cellular Biology. 24: 1870-83. PMID 14966269 DOI: 10.1128/MCB.24.5.1870-1883.2004 |
0.461 |
|
2004 |
Petrovic A, Alpdogan O, Willis LM, Eng JM, Greenberg AS, Kappel BJ, Liu C, Murphy GJ, Heller G, van den Brink MR. LPAM (alpha 4 beta 7 integrin) is an important homing integrin on alloreactive T cells in the development of intestinal graft-versus-host disease. Blood. 103: 1542-7. PMID 14563643 DOI: 10.1182/Blood-2003-03-0957 |
0.322 |
|
2003 |
Murphy GJ, Göttgens B, Vegiopoulos A, Sanchez MJ, Leavitt AD, Watson SP, Green AR, Frampton J. Manipulation of mouse hematopoietic progenitors by specific retroviral infection. The Journal of Biological Chemistry. 278: 43556-63. PMID 12928443 DOI: 10.1074/Jbc.M302717200 |
0.592 |
|
2001 |
Gaur M, Murphy GJ, deSauvage FJ, Leavitt AD. Characterization of Mpl mutants using primary megakaryocyte-lineage cells from mpl(-/-) mice: a new system for Mpl structure-function studies. Blood. 97: 1653-61. PMID 11238104 DOI: 10.1182/Blood.V97.6.1653 |
0.534 |
|
2000 |
Berlanga O, Bobe R, Becker M, Murphy G, Leduc M, Bon C, Barry FA, Gibbins JM, Garcia P, Frampton J, Watson SP. Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation. Blood. 96: 2740-2745. DOI: 10.1182/Blood.V96.8.2740.H8002740_2740_2745 |
0.451 |
|
1999 |
Shiraga M, Ritchie A, Aidoudi S, Baron V, Wilcox D, White G, Ybarrondo B, Murphy G, Leavitt A, Shattil S. Primary Megakaryocytes Reveal a Role for Transcription Factor Nf-E2 in Integrin αiibβ3 Signaling Journal of Cell Biology. 147: 1419-1430. PMID 10613901 DOI: 10.1083/Jcb.147.7.1419 |
0.361 |
|
1999 |
Murphy GJ, Leavitt AD. A model for studying megakaryocyte development and biology. Proceedings of the National Academy of Sciences of the United States of America. 96: 3065-70. PMID 10077637 DOI: 10.1073/Pnas.96.6.3065 |
0.492 |
|
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