Anne M. Gardner, Ph.D. - Publications

Affiliations: 
 
Area:
immunoglobulin misfolding, signaling kinases, NO metabolism

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gardner AM, Gardner PR. Dioxygen and glucose force motion of the electron-transfer switch in the iron(III) flavohemoglobin-type nitric oxide dioxygenase. Journal of Inorganic Biochemistry. 245: 112257. PMID 37229820 DOI: 10.1016/j.jinorgbio.2023.112257  0.515
2021 Gardner AM, Gardner PR. Correction: Allostery in the nitric oxide dioxygenase mechanism of flavohemoglobin. The Journal of Biological Chemistry. 296: 100542. PMID 34237890 DOI: 10.1016/j.jbc.2021.100542  0.514
2020 Gardner AM, Gardner PR. Allostery in the nitric-oxide dioxygenase mechanism of flavohemoglobin. The Journal of Biological Chemistry. PMID 33310705 DOI: 10.1074/jbc.RA120.016637  0.535
2010 Gardner AM, Cook MR, Gardner PR. Nitric-oxide dioxygenase function of human cytoglobin with cellular reductants and in rat hepatocytes. The Journal of Biological Chemistry. 285: 23850-7. PMID 20511233 DOI: 10.1074/Jbc.M110.132340  0.53
2008 Gardner PR, Gardner AM. Nitric oxide dioxygenase. an ancient enzymic function of hemoglobin The Smallest Biomolecules: Diatomics and Their Interactions With Heme Proteins. 290-326. DOI: 10.1016/B978-044452839-1.50013-9  0.525
2006 Gardner PR, Gardner AM, Brashear WT, Suzuki T, Hvitved AN, Setchell KD, Olson JS. Hemoglobins dioxygenate nitric oxide with high fidelity. Journal of Inorganic Biochemistry. 100: 542-50. PMID 16439024 DOI: 10.1016/J.Jinorgbio.2005.12.012  0.524
2005 Helmick RA, Fletcher AE, Gardner AM, Gessner CR, Hvitved AN, Gustin MC, Gardner PR. Imidazole antibiotics inhibit the nitric oxide dioxygenase function of microbial flavohemoglobin. Antimicrobial Agents and Chemotherapy. 49: 1837-43. PMID 15855504 DOI: 10.1128/Aac.49.5.1837-1843.2005  0.573
2004 Hallstrom CK, Gardner AM, Gardner PR. Nitric oxide metabolism in mammalian cells: substrate and inhibitor profiles of a NADPH-cytochrome P450 oxidoreductase-coupled microsomal nitric oxide dioxygenase. Free Radical Biology & Medicine. 37: 216-28. PMID 15203193 DOI: 10.1016/j.freeradbiomed.2004.04.031  0.554
2004 Gardner PR, Gardner AM, Hallstrom CK. Dioxygen-dependent metabolism of nitric oxide. Methods in Molecular Biology (Clifton, N.J.). 279: 133-50. PMID 15199242 DOI: 10.1385/1-59259-807-2:133  0.548
2003 Gardner AM, Gessner CR, Gardner PR. Regulation of the nitric oxide reduction operon (norRVW) in Escherichia coli. Role of NorR and sigma54 in the nitric oxide stress response. The Journal of Biological Chemistry. 278: 10081-6. PMID 12529359 DOI: 10.1074/Jbc.M212462200  0.545
2002 Pathania R, Navani NK, Gardner AM, Gardner PR, Dikshit KL. Nitric oxide scavenging and detoxification by the Mycobacterium tuberculosis haemoglobin, HbN in Escherichia coli. Molecular Microbiology. 45: 1303-14. PMID 12207698 DOI: 10.1046/J.1365-2958.2002.03095.X  0.546
2002 Gardner AM, Helmick RA, Gardner PR. Flavorubredoxin, an inducible catalyst for nitric oxide reduction and detoxification in Escherichia coli. The Journal of Biological Chemistry. 277: 8172-7. PMID 11751865 DOI: 10.1074/Jbc.M110471200  0.556
2002 Gardner AM, Gardner PR. Flavohemoglobin detoxifies nitric oxide in aerobic, but not anaerobic, Escherichia coli. Evidence for a novel inducible anaerobic nitric oxide-scavenging activity. The Journal of Biological Chemistry. 277: 8166-71. PMID 11751864 DOI: 10.1074/Jbc.M110470200  0.606
2001 Gardner PR, Martin LA, Hall D, Gardner AM. Dioxygen-dependent metabolism of nitric oxide in mammalian cells. Free Radical Biology & Medicine. 31: 191-204. PMID 11440831 DOI: 10.1016/S0891-5849(01)00569-X  0.572
2000 Gardner PR, Gardner AM, Martin LA, Dou Y, Li T, Olson JS, Zhu H, Riggs AF. Nitric-oxide dioxygenase activity and function of flavohemoglobins. sensitivity to nitric oxide and carbon monoxide inhibition. The Journal of Biological Chemistry. 275: 31581-7. PMID 10922365 DOI: 10.1074/Jbc.M004141200  0.548
2000 Gardner AM, Martin LA, Gardner PR, Dou Y, Olson JS. Steady-state and transient kinetics of Escherichia coli nitric-oxide dioxygenase (flavohemoglobin). The B10 tyrosine hydroxyl is essential for dioxygen binding and catalysis. The Journal of Biological Chemistry. 275: 12581-9. PMID 10777548 DOI: 10.1074/Jbc.275.17.12581  0.559
2000 Gardner AM, Martin LA, Gardner PR, Dou Y, Olson JS, Kurtz D.M. J. Steady-state and transient kinetics of Escherichia coli nitric oxide dioxygenase (Flavohemoglobin) Chemtracts. 13: 534-538.  0.521
1999 Gardner PR, Martin LA, Gardner AM. Nitric oxide detoxification by an O2-dependent cyanide-sensitive pathway in mammalian cells: Protection of the aconitases Free Radical Biology and Medicine. 27: S75. DOI: 10.1016/S0891-5849(99)90753-0  0.577
1998 Gardner PR, Gardner AM, Martin LA, Salzman AL. Nitric oxide dioxygenase: an enzymic function for flavohemoglobin. Proceedings of the National Academy of Sciences of the United States of America. 95: 10378-83. PMID 9724711 DOI: 10.1073/Pnas.95.18.10378  0.578
1997 Widmann C, Johnson NL, Gardner AM, Smith RJ, Johnson GL. Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1. Oncogene. 15: 2439-47. PMID 9395240 DOI: 10.1038/Sj.Onc.1201421  0.556
1996 Vaillancourt RR, Gardner AM, Kazlauskas A, Johnson GL. The kinase-inactive PDGF beta-receptor mediates activation of the MAP kinase cascade via the endogenous PDGF alpha-receptor in HepG2 cells. Oncogene. 13: 151-9. PMID 8700541  0.462
1996 Gardner AM, Johnson GL. Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase. The Journal of Biological Chemistry. 271: 14560-6. PMID 8662985 DOI: 10.1074/Jbc.271.24.14560  0.504
1996 Johnson NL, Gardner AM, Diener KM, Lange-Carter CA, Gleavy J, Jarpe MB, Minden A, Karin M, Zon LI, Johnson GL. Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death. The Journal of Biological Chemistry. 271: 3229-37. PMID 8621725 DOI: 10.1074/Jbc.271.6.3229  0.569
1995 Winston BW, Lange-Carter CA, Gardner AM, Johnson GL, Riches DW. Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAPK kinase kinase-dependent, c-Raf-1-independent fashion in mouse macrophages. Proceedings of the National Academy of Sciences of the United States of America. 92: 1614-8. PMID 7878028 DOI: 10.1073/Pnas.92.5.1614  0.493
1994 Franklin RA, Tordai A, Patel H, Gardner AM, Johnson GL, Gelfand EW. Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes. The Journal of Clinical Investigation. 93: 2134-40. PMID 8182145 DOI: 10.1172/Jci117209  0.545
1994 Tordai A, Franklin RA, Patel H, Gardner AM, Johnson GL, Gelfand EW. Cross-linking of surface IgM stimulates the Ras/Raf-1/MEK/MAPK cascade in human B lymphocytes. The Journal of Biological Chemistry. 269: 7538-43. PMID 8125975  0.508
1994 Gardner AM, Vaillancourt RR, Lange-Carter CA, Johnson GL. MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity. Molecular Biology of the Cell. 5: 193-201. PMID 8019005 DOI: 10.1091/Mbc.5.2.193  0.55
1994 Johnson GL, Gardner AM, Lange-Carter C, Qian NX, Russell M, Winitz S. How does the G protein, Gi2, transduce mitogenic signals? Journal of Cellular Biochemistry. 54: 415-22. PMID 8014190 DOI: 10.1002/Jcb.240540408  0.557
1994 Vaillancourt RR, Gardner AM, Johnson GL. B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP. Molecular and Cellular Biology. 14: 6522-30. PMID 7935374 DOI: 10.1128/Mcb.14.10.6522  0.554
1994 Gardner AM, Lange-Carter CA, Vaillancourt RR, Johnson GL. Measuring activation of kinases in mitogen-activated protein kinase regulatory network. Methods in Enzymology. 238: 258-70. PMID 7799792 DOI: 10.1016/0076-6879(94)38024-4  0.535
1993 Gardner AM, Vaillancourt RR, Johnson GL. Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase by G protein and tyrosine kinase oncoproteins. The Journal of Biological Chemistry. 268: 17896-901. PMID 8394352  0.523
1993 Lange-Carter CA, Pleiman CM, Gardner AM, Blumer KJ, Johnson GL. A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science (New York, N.Y.). 260: 315-9. PMID 8385802 DOI: 10.1126/Science.8385802  0.548
1993 Gardner AM, Aviel S, Argon Y. Rapid degradation of an unassembled immunoglobulin light chain is mediated by a serine protease and occurs in a pre-Golgi compartment. The Journal of Biological Chemistry. 268: 25940-7. PMID 8245027  0.54
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