Jacqueline A. Lees - Publications

Affiliations: 
Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
tumorigenicity
Website:
https://ki.mit.edu/people/faculty/lees

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Mori M, Hazan R, Danielian PS, Mahoney JE, Li H, Lu J, Miller ES, Zhu X, Lees JA, Cardoso WV. Author Correction: Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis. Nature Communications. 9: 16157. PMID 30451964 DOI: 10.1038/ncomms16157  0.32
2018 Perez DE, Henle AM, Amsterdam A, Hagen HR, Lees JA. Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology. Pigment Cell & Melanoma Research. PMID 29570931 DOI: 10.1111/pcmr.12700  0.32
2017 Mori M, Hazan R, Danielian PS, Mahoney JE, Li H, Lu J, Miller ES, Zhu X, Lees JA, Cardoso WV. Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis. Nature Communications. 8: 15857. PMID 28675157 DOI: 10.1038/ncomms15857  0.32
2016 Danielian PS, Hess RA, Lees JA. E2f4 and E2f5 are essential for the development of the male reproductive system. Cell Cycle (Georgetown, Tex.). 15: 250-60. PMID 26825228 DOI: 10.1080/15384101.2015.1121350  0.32
2015 Nicolay BN, Danielian PS, Kottakis F, Lapek JD, Sanidas I, Miles WO, Dehnad M, Tschöp K, Gierut JJ, Manning AL, Morris R, Haigis K, Bardeesy N, Lees JA, Haas W, et al. Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation. Genes & Development. 29: 1875-89. PMID 26314710 DOI: 10.1101/gad.264127.115  0.32
2015 Percival SM, Thomas HR, Amsterdam A, Carroll AJ, Lees JA, Yost HJ, Parant JM. Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome. Disease Models & Mechanisms. 8: 941-55. PMID 26044958 DOI: 10.1242/dmm.019059  0.32
2013 Zhang G, Hoersch S, Amsterdam A, Whittaker CA, Beert E, Catchen JM, Farrington S, Postlethwait JH, Legius E, Hopkins N, Lees JA. Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery. Plos Genetics. 9: e1003734. PMID 24009526 DOI: 10.1371/journal.pgen.1003734  0.32
2013 Hilgendorf KI, Leshchiner ES, Nedelcu S, Maynard MA, Calo E, Ianari A, Walensky LD, Lees JA. The retinoblastoma protein induces apoptosis directly at the mitochondria. Genes & Development. 27: 1003-15. PMID 23618872 DOI: 10.1101/gad.211326.112  0.32
2012 Ravi A, Gurtan AM, Kumar MS, Bhutkar A, Chin C, Lu V, Lees JA, Jacks T, Sharp PA. Proliferation and tumorigenesis of a murine sarcoma cell line in the absence of DICER1. Cancer Cell. 21: 848-55. PMID 22698408 DOI: 10.1016/j.ccr.2012.04.037  0.32
2010 Zhang G, Hoersch S, Amsterdam A, Whittaker CA, Lees JA, Hopkins N. Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers. Proceedings of the National Academy of Sciences of the United States of America. 107: 16940-5. PMID 20837522 DOI: 10.1073/pnas.1011548107  0.32
2010 Calo E, Quintero-Estades JA, Danielian PS, Nedelcu S, Berman SD, Lees JA. Rb regulates fate choice and lineage commitment in vivo. Nature. 466: 1110-4. PMID 20686481 DOI: 10.1038/nature09264  0.32
2010 Miller ES, Berman SD, Yuan TL, Lees JA. Disruption of calvarial ossification in E2f4 mutant embryos correlates with increased proliferation and progenitor cell populations. Cell Cycle (Georgetown, Tex.). 9: 2620-8. PMID 20581455 DOI: 10.4161/cc.9.13.12108  0.32
2010 Sansam CL, Cruz NM, Danielian PS, Amsterdam A, Lau ML, Hopkins N, Lees JA. A vertebrate gene, ticrr, is an essential checkpoint and replication regulator. Genes & Development. 24: 183-94. PMID 20080954 DOI: 10.1101/gad.1860310  0.32
2010 Zhang J, Lee EY, Liu Y, Berman SD, Lodish HF, Lees JA. pRB and E2F4 play distinct cell-intrinsic roles in fetal erythropoiesis. Cell Cycle (Georgetown, Tex.). 9: 371-6. PMID 20023434 DOI: 10.4161/cc.9.2.10467  0.32
2009 Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA. Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects. Proceedings of the National Academy of Sciences of the United States of America. 106: 14932-6. PMID 19706423 DOI: 10.1073/pnas.0902408106  0.32
2009 Amsterdam A, Lai K, Komisarczuk AZ, Becker TS, Bronson RT, Hopkins N, Lees JA. Zebrafish Hagoromo mutants up-regulate fgf8 postembryonically and develop neuroblastoma. Molecular Cancer Research : McR. 7: 841-50. PMID 19531571 DOI: 10.1158/1541-7786.MCR-08-0555  0.32
2009 Lee EY, Yuan TL, Danielian PS, West JC, Lees JA. E2F4 cooperates with pRB in the development of extra-embryonic tissues. Developmental Biology. 332: 104-15. PMID 19433082 DOI: 10.1016/j.ydbio.2009.05.541  0.32
2009 Lai K, Amsterdam A, Farrington S, Bronson RT, Hopkins N, Lees JA. Many ribosomal protein mutations are associated with growth impairment and tumor predisposition in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 76-85. PMID 19097187 DOI: 10.1002/dvdy.21815  0.32
2008 Berman SD, Yuan TL, Miller ES, Lee EY, Caron A, Lees JA. The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development. Molecular Cancer Research : McR. 6: 1440-51. PMID 18819932 DOI: 10.1158/1541-7786.MCR-08-0176  0.32
2008 Berman SD, Calo E, Landman AS, Danielian PS, Miller ES, West JC, Fonhoue BD, Caron A, Bronson R, Bouxsein ML, Mukherjee S, Lees JA. Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proceedings of the National Academy of Sciences of the United States of America. 105: 11851-6. PMID 18697945 DOI: 10.1073/pnas.0805462105  0.32
2008 Dovey JS, Zacharek SJ, Kim CF, Lees JA. Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion. Proceedings of the National Academy of Sciences of the United States of America. 105: 11857-62. PMID 18697930 DOI: 10.1073/pnas.0803574105  0.32
2008 MacInnes AW, Amsterdam A, Whittaker CA, Hopkins N, Lees JA. Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations. Proceedings of the National Academy of Sciences of the United States of America. 105: 10408-13. PMID 18641120 DOI: 10.1073/pnas.0805036105  0.32
2007 Conboy CM, Spyrou C, Thorne NP, Wade EJ, Barbosa-Morais NL, Wilson MD, Bhattacharjee A, Young RA, Tavaré S, Lees JA, Odom DT. Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor. Plos One. 2: e1061. PMID 17957245 DOI: 10.1371/journal.pone.0001061  0.32
2007 Danielian PS, Bender Kim CF, Caron AM, Vasile E, Bronson RT, Lees JA. E2f4 is required for normal development of the airway epithelium. Developmental Biology. 305: 564-76. PMID 17383628 DOI: 10.1016/j.ydbio.2007.02.037  0.32
2007 Reinhardt HC, Aslanian AS, Lees JA, Yaffe MB. p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage. Cancer Cell. 11: 175-89. PMID 17292828 DOI: 10.1016/j.ccr.2006.11.024  0.32
2007 Parisi T, Yuan TL, Faust AM, Caron AM, Bronson R, Lees JA. Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues. Molecular and Cellular Biology. 27: 2283-93. PMID 17210634 DOI: 10.1128/MCB.01854-06  0.32
2006 Sansam CL, Shepard JL, Lai K, Ianari A, Danielian PS, Amsterdam A, Hopkins N, Lees JA. DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint. Genes & Development. 20: 3117-29. PMID 17085480 DOI: 10.1101/gad.1482106  0.32
2004 Amsterdam A, Sadler KC, Lai K, Farrington S, Bronson RT, Lees JA, Hopkins N. Many ribosomal protein genes are cancer genes in zebrafish. Plos Biology. 2: E139. PMID 15138505 DOI: 10.1371/journal.pbio.0020139  0.32
2003 Ziebold U, Lee EY, Bronson RT, Lees JA. E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas. Molecular and Cellular Biology. 23: 6542-52. PMID 12944480 DOI: 10.1128/MCB.23.18.6542-6552.2003  0.32
2003 Baudino TA, Maclean KH, Brennan J, Parganas E, Yang C, Aslanian A, Lees JA, Sherr CJ, Roussel MF, Cleveland JL. Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss. Molecular Cell. 11: 905-14. PMID 12718877 DOI: 10.1016/S1097-2765(03)00102-3  0.32
2003 Landsberg RL, Sero JE, Danielian PS, Yuan TL, Lee EY, Lees JA. The role of E2F4 in adipogenesis is independent of its cell cycle regulatory activity. Proceedings of the National Academy of Sciences of the United States of America. 100: 2456-61. PMID 12604789 DOI: 10.1073/pnas.0138064100  0.32
2002 Lee EY, Cam H, Ziebold U, Rayman JB, Lees JA, Dynlacht BD. E2F4 loss suppresses tumorigenesis in Rb mutant mice. Cancer Cell. 2: 463-72. PMID 12498715 DOI: 10.1016/S1535-6108(02)00207-6  0.32
2002 Fajas L, Landsberg RL, Huss-Garcia Y, Sardet C, Lees JA, Auwerx J. E2Fs regulate adipocyte differentiation. Developmental Cell. 3: 39-49. PMID 12110166 DOI: 10.1016/S1534-5807(02)00190-9  0.32
2002 Cloud JE, Rogers C, Reza TL, Ziebold U, Stone JR, Picard MH, Caron AM, Bronson RT, Lees JA. Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo. Molecular and Cellular Biology. 22: 2663-72. PMID 11909960 DOI: 10.1128/MCB.22.8.2663-2672.2002  0.32
2002 Trimarchi JM, Lees JA. Sibling rivalry in the E2F family. Nature Reviews. Molecular Cell Biology. 3: 11-20. PMID 11823794 DOI: 10.1038/nrm714  0.92
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