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David Frederick Stern - Publications

Affiliations: 
1988- Pathology Yale University, New Haven, CT 
Area:
Receptors and Signal Transduction
Website:
http://bbs.yale.edu/people/df_stern.profile

115 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gale M, Li Y, Cao J, Liu ZZ, Holmbeck MA, Zhang M, Lang SM, Wu L, Do Carmo M, Gupta S, Aoshima K, DiGiovanna MP, Stern DF, Rimm DL, Shadel GS, et al. Acquired resistance to HER2-targeted therapies creates vulnerability to ATP synthase inhibition. Cancer Research. PMID 31690671 DOI: 10.1158/0008-5472.Can-18-3985  0.333
2019 Colavito SA, Platt JT, Held MA, Liu Z, Sokup R, Stern DF. Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer. Oncotarget. 10: 4822-4839. PMID 31448050 DOI: 10.18632/Oncotarget.27104  0.378
2018 Theodosakis N, Langdon CG, Micevic G, Krykbaeva I, Means RE, Stern DF, Bosenberg MW. Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment-resistant melanoma, colorectal, and lung cancer. Pigment Cell & Melanoma Research. PMID 30281931 DOI: 10.1111/Pcmr.12742  0.337
2018 Stern DF. Keeping Tumors Out of the MAPK Fitness Zone. Cancer Discovery. 8: 20-23. PMID 29311225 DOI: 10.1158/2159-8290.Cd-17-1243  0.351
2017 Klein MI, Stern DF, Zhao H. GRAPE: a pathway template method to characterize tissue-specific functionality from gene expression profiles. Bmc Bioinformatics. 18: 317. PMID 28651562 DOI: 10.1186/S12859-017-1711-Z  0.302
2017 Theodosakis N, Micevic G, Langdon CG, Ventura A, Means R, Stern DF, Bosenberg MW. p90RSK blockade inhibits dual BRAF and MEK inhibitor-resistant melanoma by targeting protein synthesis. The Journal of Investigative Dermatology. PMID 28599981 DOI: 10.1016/J.Jid.2016.12.033  0.366
2017 Langdon CG, Platt JT, Means RE, Iyidogan P, Mamillapalli R, Klein M, Held MA, Lee JW, Koo JS, Hatzis C, Hochster HS, Stern DF. Combinatorial screening of pancreatic adenocarcinoma reveals sensitivity to drug combinations including bromodomain inhibitor plus neddylation inhibitor. Molecular Cancer Therapeutics. PMID 28292938 DOI: 10.1158/1535-7163.Mct-16-0794  0.359
2016 Wali VB, Langdon CG, Held MA, Platt JT, Patwardhan GA, Safonov A, Aktas B, Pusztai L, Stern DF, Hatzis C. Systematic drug screening identifies tractable targeted combination therapies in triple-negative breast cancer. Cancer Research. PMID 27872098 DOI: 10.1158/0008-5472.Can-16-1901  0.365
2016 Jeong J, VanHouten JN, Dann P, Kim W, Sullivan C, Yu H, Liotta L, Espina V, Stern DF, Friedman PA, Wysolmerski JJ. PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 26729871 DOI: 10.1073/Pnas.1516138113  0.383
2015 Haskins JW, Zhang S, Means RE, Kelleher JK, Cline GW, Canfrán-Duque A, Suárez Y, Stern DF. Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake. Science Signaling. 8: ra111. PMID 26535009 DOI: 10.1126/Scisignal.Aac5124  0.418
2015 Langdon CG, Wiedemann N, Held MA, Mamillapalli R, Iyidogan P, Theodosakis N, Platt JT, Levy F, Vuagniaux G, Wang S, Bosenberg MW, Stern DF. SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells. Oncotarget. PMID 26485762 DOI: 10.18632/Oncotarget.6138  0.358
2015 Theodosakis N, Held MA, Marzuka-Alcala A, Meeth KM, Micevic G, Long GV, Scolyer RA, Stern DF, Bosenberg MW. BRAF Inhibition Decreases Cellular Glucose Uptake in Melanoma in Association with Reduction in Cell Volume. Molecular Cancer Therapeutics. 14: 1680-92. PMID 25948295 DOI: 10.1158/1535-7163.Mct-15-0080  0.33
2015 Langdon CG, Held MA, Platt JT, Meeth K, Iyidogan P, Mamillapalli R, Koo AB, Klein M, Liu Z, Bosenberg MW, Stern DF. The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors. Pigment Cell & Melanoma Research. 28: 417-30. PMID 25854919 DOI: 10.1111/Pcmr.12376  0.396
2015 Scortegagna M, Lau E, Zhang T, Feng Y, Sereduk C, Yin H, De SK, Meeth K, Platt JT, Langdon CG, Halaban R, Pellecchia M, Davies MA, Brown K, Stern DF, et al. PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets. Cancer Research. 75: 1399-412. PMID 25712345 DOI: 10.1158/0008-5472.Can-14-2785  0.419
2015 Langdon CG, Wiedemann N, Held MA, Platt JT, Mamillapalli R, Iyidogan P, Theodosakis N, Levy F, Robichon D, Zanna C, Vuagniaux G, Sorensen M, Wang S, Bosenberg MW, Stern DF. Abstract 2529: Debio 1143 synergizes with taxanes, topoisomerase and bromodomain inhibitors to inhibit growth of lung adenocarcinoma Cancer Research. 75: 2529-2529. DOI: 10.1158/1538-7445.Am2015-2529  0.355
2014 Wali VB, Gilmore-Hebert M, Mamillapalli R, Haskins JW, Kurppa KJ, Elenius K, Booth CJ, Stern DF. Overexpression of ERBB4 JM-a CYT-1 and CYT-2 isoforms in transgenic mice reveals isoform-specific roles in mammary gland development and carcinogenesis. Breast Cancer Research : Bcr. 16: 501. PMID 25516216 DOI: 10.1186/S13058-014-0501-Z  0.464
2014 Haskins JW, Nguyen DX, Stern DF. Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration. Science Signaling. 7: ra116. PMID 25492965 DOI: 10.1126/Scisignal.2005770  0.512
2014 Colavito SA, Zou MR, Yan Q, Nguyen DX, Stern DF. Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway. Breast Cancer Research : Bcr. 16: 444. PMID 25252859 DOI: 10.1186/S13058-014-0444-4  0.429
2014 Wali VB, Haskins JW, Gilmore-Hebert M, Platt JT, Liu Z, Stern DF. Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells. Molecular Cancer Research : McR. 12: 1140-55. PMID 24829397 DOI: 10.1158/1541-7786.Mcr-13-0637  0.461
2014 Langdon CG, Wiedemann N, Held MA, Platt JT, Lévy F, Robichon D, Zanna C, Vuagniaux G, Sorensen M, Wang S, Bosenberg MW, Stern DF. Abstract 5441: Debio 1143, an oral antagonist of the inhibitor of apoptosis proteins, synergistically enhances the effects of multiple standard of care agents in human lung cancer models Cancer Research. 74: 5441-5441. DOI: 10.1158/1538-7445.Am2014-5441  0.347
2014 Langdon CG, Wiedemann N, Hajjami HM, Held MA, Platt JT, Vuagniaux G, Bosenberg MW, Stern DF, Lévy F. Abstract 1792: Identification of synergistic drug combinations with the oral HSP90 inhibitor Debio 0932 in non-small cell lung cancer and renal cell cancer Cancer Research. 74: 1792-1792. DOI: 10.1158/1538-7445.Am2014-1792  0.352
2013 Bai Y, Cheng H, Bordeaux J, Neumeister V, Kumar S, Rimm DL, Stern DF. Comparison of HER2 and phospho-HER2 expression between biopsy and resected breast cancer specimens using a quantitative assessment method. Plos One. 8: e79901. PMID 24278211 DOI: 10.1371/Journal.Pone.0079901  0.315
2013 Breindel JL, Haskins JW, Cowell EP, Zhao M, Nguyen DX, Stern DF. EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Cancer Research. 73: 5053-65. PMID 23794705 DOI: 10.1158/0008-5472.Can-12-3775  0.776
2013 Tworkoski KA, Platt JT, Bacchiocchi A, Bosenberg M, Boggon TJ, Stern DF. MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL. Pigment Cell & Melanoma Research. 26: 527-41. PMID 23617806 DOI: 10.1111/Pcmr.12110  0.775
2013 Held MA, Langdon CG, Platt JT, Graham-Steed T, Liu Z, Chakraborty A, Bacchiocchi A, Koo A, Haskins JW, Bosenberg MW, Stern DF. Genotype-selective combination therapies for melanoma identified by high-throughput drug screening. Cancer Discovery. 3: 52-67. PMID 23239741 DOI: 10.1158/2159-8290.Cd-12-0408  0.331
2013 Park S, Platt J, Park HS, Lee JW, Stern DF, Herbst RS, Koo JP. Abstract 4382: Genome-Wide Gene Expression analysis and molecular portraits regulated by NASEp, an inhibitor of CREB and CBP interaction, in non-small cell lung cancer. Cancer Research. 73: 4382-4382. DOI: 10.1158/1538-7445.Am2013-4382  0.416
2013 Wali VB, Gilmore-Hebert M, Elenius K, Stern DF. Abstract 1401: Overexpression of HER4 isoforms in transgenic mice reveal isoform-specific role in mammary gland development and carcinogenesis. Cancer Research. 73: 1401-1401. DOI: 10.1158/1538-7445.Am2013-1401  0.419
2013 Langdon CG, Held MA, Koo AB, Klein M, Liu Z, Platt JT, Stern DF. Abstract B275: Dovitinib as a single-agent or in combination with other small molecule inhibitors for mutant BRAF melanomas. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B275  0.37
2013 Langdon CG, Wiedemann N, Held MA, Platt JT, Lévy F, Zanna C, Vuagniaux G, Sorensen M, Wang S, Bosenberg MW, Stern DF. Abstract A16: A drug combination screen identifies taxanes as synergistic agents with the oral IAP inhibitor Debio 1143 in non-small cell lung cancer cells. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A16  0.362
2012 Krauthammer M, Kong Y, Ha BH, Evans P, Bacchiocchi A, McCusker JP, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, ... ... Stern DF, et al. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nature Genetics. 44: 1006-14. PMID 22842228 DOI: 10.1038/Ng.2359  0.337
2012 Liu J, Luo S, Zhao H, Liao J, Li J, Yang C, Xu B, Stern DF, Xu X, Ye K. Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain. Nucleic Acids Research. 40: 3898-912. PMID 22234877 DOI: 10.1093/Nar/Gkr1296  0.307
2011 Singhal G, Akhter MZ, Stern DF, Gupta SD, Ahuja A, Sharma U, Jagannathan NR, Rajeswari MR. DNA triplex-mediated inhibition of MET leads to cell death and tumor regression in hepatoma. Cancer Gene Therapy. 18: 520-30. PMID 21660063 DOI: 10.1038/Cgt.2011.21  0.425
2011 Wilson KA, Colavito SA, Schulz V, Wakefield PH, Sessa W, Tuck D, Stern DF. NFBD1/MDC1 regulates Cav1 and Cav2 independently of DNA damage and p53. Molecular Cancer Research : McR. 9: 766-81. PMID 21551225 DOI: 10.1158/1541-7786.Mcr-10-0317  0.362
2011 Tworkoski K, Singhal G, Szpakowski S, Zito CI, Bacchiocchi A, Muthusamy V, Bosenberg M, Krauthammer M, Halaban R, Stern DF. Phosphoproteomic screen identifies potential therapeutic targets in melanoma. Molecular Cancer Research : McR. 9: 801-12. PMID 21521745 DOI: 10.1158/1541-7786.Mcr-10-0512  0.797
2011 Godshalk SE, Paranjape T, Nallur S, Speed W, Chan E, Molinaro AM, Bacchiocchi A, Hoyt K, Tworkoski K, Stern DF, Sznol M, Ariyan S, Lazova R, Halaban R, Kidd KK, et al. A Variant in a MicroRNA complementary site in the 3' UTR of the KIT oncogene increases risk of acral melanoma. Oncogene. 30: 1542-50. PMID 21119596 DOI: 10.1038/Onc.2010.536  0.742
2010 Stern DF. EGFs and ERBBs--brief history and prospects. Seminars in Cell & Developmental Biology. 21: 917-21. PMID 20970513 DOI: 10.1016/J.Semcdb.2010.10.006  0.379
2010 Gilmore-Hebert M, Ramabhadran R, Stern DF. Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways. Molecular Cancer Research : McR. 8: 1388-98. PMID 20858735 DOI: 10.1158/1541-7786.Mcr-10-0042  0.471
2010 Golan A, Pick E, Tsvetkov L, Nadler Y, Kluger H, Stern DF. Centrosomal Chk2 in DNA damage responses and cell cycle progression. Cell Cycle (Georgetown, Tex.). 9: 2647-56. PMID 20581449 DOI: 10.4161/Cc.9.13.12121  0.342
2010 Mok J, Kim PM, Lam HY, Piccirillo S, Zhou X, Jeschke GR, Sheridan DL, Parker SA, Desai V, Jwa M, Cameroni E, Niu H, Good M, Remenyi A, Ma JL, ... ... Stern DF, et al. Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Science Signaling. 3: ra12. PMID 20159853 DOI: 10.1126/Scisignal.2000482  0.406
2010 Singhal G, Stern D, Gupta SD, Ahuja A, Sharma U, Jagannathan N, Rajeswari M. 532 Down-regulation of MET via DNA triplex-forming oligodeoxyribonucleotides targeting the promoter of c-Met gene results in growth inhibition and apoptosis in liver cancer European Journal of Cancer Supplements. 8: 170. DOI: 10.1016/S1359-6349(10)72239-4  0.339
2009 Agarwal S, Zerillo C, Kolmakova J, Christensen JG, Harris LN, Rimm DL, Digiovanna MP, Stern DF. Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells. British Journal of Cancer. 100: 941-9. PMID 19240716 DOI: 10.1038/Sj.Bjc.6604937  0.459
2009 Stern DF. BRCTing up is hard to do. Molecular Cell. 33: 137-8. PMID 19187753 DOI: 10.1016/J.Molcel.2009.01.005  0.329
2008 Jackson-Fisher AJ, Bellinger G, Breindel JL, Tavassoli FA, Booth CJ, Duong JK, Stern DF. ErbB3 is required for ductal morphogenesis in the mouse mammary gland. Breast Cancer Research : Bcr. 10: R96. PMID 19019207 DOI: 10.1186/Bcr2198  0.758
2008 Wilson KA, Stern DF. NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway. Cell Cycle (Georgetown, Tex.). 7: 3584-94. PMID 19001859 DOI: 10.4161/Cc.7.22.7102  0.344
2008 Stern DF. ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer. Journal of Mammary Gland Biology and Neoplasia. 13: 215-23. PMID 18454306 DOI: 10.1007/S10911-008-9083-7  0.486
2008 Zito CI, Riches D, Kolmakova J, Simons J, Egholm M, Stern DF. Direct resequencing of the complete ERBB2 coding sequence reveals an absence of activating mutations in ERBB2 amplified breast cancer. Genes, Chromosomes & Cancer. 47: 633-8. PMID 18418848 DOI: 10.1002/Gcc.20566  0.358
2008 DiGiovanna MP, Stern DF, Edgerton S, Broadwater G, Dressler LG, Budman DR, Henderson IC, Norton L, Liu ET, Muss HB, Berry DA, Hayes DF, Thor AD. Influence of activation state of ErbB-2 (HER-2) on response to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for stage II, node-positive breast cancer: study 8541 from the Cancer and Leukemia Group B. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 2364-72. PMID 18390970 DOI: 10.1200/Jco.2007.13.6580  0.392
2008 Jia-Lin Ma N, Stern DF. Regulation of the Rad53 protein kinase in signal amplification by oligomer assembly and disassembly. Cell Cycle (Georgetown, Tex.). 7: 808-17. PMID 18239457 DOI: 10.4161/Cc.7.6.5595  0.384
2006 Jackson-Fisher AJ, Bellinger G, Shum E, Duong JK, Perkins AS, Gassmann M, Muller W, Kent Lloyd KC, Stern DF. Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4. Oncogene. 25: 5664-72. PMID 16652155 DOI: 10.1038/Sj.Onc.1209574  0.386
2006 Ma JL, Lee SJ, Duong JK, Stern DF. Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1. The Journal of Biological Chemistry. 281: 3954-63. PMID 16365046 DOI: 10.1074/Jbc.M507508200  0.405
2005 Ptacek J, Devgan G, Michaud G, Zhu H, Zhu X, Fasolo J, Guo H, Jona G, Breitkreutz A, Sopko R, McCartney RR, Schmidt MC, Rachidi N, Lee SJ, Mah AS, ... ... Stern DF, et al. Global analysis of protein phosphorylation in yeast. Nature. 438: 679-84. PMID 16319894 DOI: 10.1038/Nature04187  0.391
2005 Modi S, DiGiovanna MP, Lu Z, Moskowitz C, Panageas KS, Van Poznak C, Hudis CA, Norton L, Tan L, Stern DF, Carter D, Seidman AD. Phosphorylated/activated HER2 as a marker of clinical resistance to single agent taxane chemotherapy for metastatic breast cancer. Cancer Investigation. 23: 483-7. PMID 16203655 DOI: 10.1080/07357900500201301  0.341
2005 Li J, Stern DF. DNA damage regulates Chk2 association with chromatin. The Journal of Biological Chemistry. 280: 37948-56. PMID 16150728 DOI: 10.1074/Jbc.M509299200  0.336
2005 Stern DF. Phosphoproteomics for oncology discovery and treatment. Expert Opinion On Therapeutic Targets. 9: 851-60. PMID 16083347 DOI: 10.1517/14728222.9.4.851  0.421
2005 Amin DN, Tuck D, Stern DF. Neuregulin-regulated gene expression in mammary carcinoma cells. Experimental Cell Research. 309: 12-23. PMID 15963498 DOI: 10.1016/J.Yexcr.2005.04.034  0.776
2005 Tsvetkov LM, Tsekova RT, Xu X, Stern DF. The Plk1 Polo box domain mediates a cell cycle and DNA damage regulated interaction with Chk2. Cell Cycle (Georgetown, Tex.). 4: 609-17. PMID 15876876 DOI: 10.4161/Cc.4.4.1599  0.388
2005 DiGiovanna MP, Stern DF, Edgerton SM, Whalen SG, Moore D, Thor AD. Relationship of epidermal growth factor receptor expression to ErbB-2 signaling activity and prognosis in breast cancer patients. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 1152-60. PMID 15718311 DOI: 10.1200/Jco.2005.09.055  0.411
2005 Li J, Stern DF. Regulation of CHK2 by DNA-dependent protein kinase. The Journal of Biological Chemistry. 280: 12041-50. PMID 15668230 DOI: 10.1074/Jbc.M412445200  0.381
2005 Tsvetkov L, Stern DF. Interaction of chromatin-associated Plk1 and Mcm7. The Journal of Biological Chemistry. 280: 11943-7. PMID 15654075 DOI: 10.1074/Jbc.M413514200  0.352
2005 Tsvetkov L, Stern DF. Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage. Cell Cycle (Georgetown, Tex.). 4: 166-71. PMID 15611664 DOI: 10.4161/Cc.4.1.1348  0.4
2004 Jackson-Fisher AJ, Bellinger G, Ramabhadran R, Morris JK, Lee KF, Stern DF. ErbB2 is required for ductal morphogenesis of the mammary gland. Proceedings of the National Academy of Sciences of the United States of America. 101: 17138-43. PMID 15569931 DOI: 10.1073/Pnas.0407057101  0.417
2004 Lee SJ, Duong JK, Stern DF. A Ddc2-Rad53 fusion protein can bypass the requirements for RAD9 and MRC1 in Rad53 activation. Molecular Biology of the Cell. 15: 5443-55. PMID 15456903 DOI: 10.1091/Mbc.E04-07-0608  0.35
2004 Xu X, Lee J, Stern DF. Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. The Journal of Biological Chemistry. 279: 34091-4. PMID 15220350 DOI: 10.1074/Jbc.C400139200  0.345
2004 Xu X, Stern DF. Establishment of a cell-free system to study the activation of Chk2. Methods in Molecular Biology (Clifton, N.J.). 280: 165-74. PMID 15187252 DOI: 10.1385/1-59259-788-2:165  0.407
2004 Amin DN, Perkins AS, Stern DF. Gene expression profiling of ErbB receptor and ligand-dependent transcription. Oncogene. 23: 1428-38. PMID 14973552 DOI: 10.1038/Sj.Onc.1207257  0.765
2003 Xu X, Stern DF. NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1842-8. PMID 14519663 DOI: 10.1096/Fj.03-0310Com  0.333
2003 Lee SJ, Schwartz MF, Duong JK, Stern DF. Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling. Molecular and Cellular Biology. 23: 6300-14. PMID 12917350 DOI: 10.1128/Mcb.23.17.6300-6314.2003  0.391
2003 Schwartz MF, Lee SJ, Duong JK, Eminaga S, Stern DF. FHA domain-mediated DNA checkpoint regulation of Rad53. Cell Cycle (Georgetown, Tex.). 2: 384-96. PMID 12851493 DOI: 10.4161/Cc.2.4.457  0.345
2003 Stern DF. ErbBs in mammary development. Experimental Cell Research. 284: 89-98. PMID 12648468 DOI: 10.1016/S0014-4827(02)00103-9  0.44
2003 Xu X, Stern DF. NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways. The Journal of Biological Chemistry. 278: 8795-803. PMID 12499369 DOI: 10.1074/Jbc.M211392200  0.332
2003 Tsvetkov L, Xu X, Li J, Stern DF. Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody. The Journal of Biological Chemistry. 278: 8468-75. PMID 12493754 DOI: 10.1074/Jbc.M211202200  0.362
2002 DiGiovanna MP, Roussel RR, Stern DF. Production of antibodies that recognize specific tyrosine-phosphorylated peptides. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 16.6. PMID 18228399 DOI: 10.1002/0471143030.Cb1606S13  0.338
2002 Schwartz MF, Duong JK, Sun Z, Morrow JS, Pradhan D, Stern DF. Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. Molecular Cell. 9: 1055-65. PMID 12049741 DOI: 10.1016/S1097-2765(02)00532-4  0.352
2002 Xu X, Tsvetkov LM, Stern DF. Chk2 activation and phosphorylation-dependent oligomerization. Molecular and Cellular Biology. 22: 4419-32. PMID 12024051 DOI: 10.1128/Mcb.22.12.4419-4432.2002  0.405
2001 Claus EB, Chu P, Howe CL, Davison TL, Stern DF, Carter D, DiGiovanna MP. Pathobiologic findings in DCIS of the breast: morphologic features, angiogenesis, HER-2/neu and hormone receptors. Experimental and Molecular Pathology. 70: 303-16. PMID 11418009 DOI: 10.1006/Exmp.2001.2366  0.325
2000 Stern DF. Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases. Breast Cancer Research : Bcr. 2: 176-83. PMID 11250707 DOI: 10.1186/Bcr51  0.464
2000 Thor AD, Liu S, Edgerton S, Moore D, Kasowitz KM, Benz CC, Stern DF, DiGiovanna MP. Activation (tyrosine phosphorylation) of ErbB-2 (HER-2/neu): a study of incidence and correlation with outcome in breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 18: 3230-9. PMID 10986055 DOI: 10.1200/Jco.2000.18.18.3230  0.361
1999 Russell KS, Stern DF, Polverini PJ, Bender JR. Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis. American Journal of Physiology. Heart and Circulatory Physiology. 277: H2205-H2211. PMID 29592287 DOI: 10.1152/Ajpheart.1999.277.6.H2205  0.425
1999 Jones FE, Welte T, Fu XY, Stern DF. ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation. The Journal of Cell Biology. 147: 77-88. PMID 10508857 DOI: 10.1083/Jcb.147.1.77  0.45
1999 Jones FE, Stern DF. Expression of dominant-negative ErbB2 in the mammary gland of transgenic mice reveals a role in lobuloalveolar development and lactation. Oncogene. 18: 3481-90. PMID 10376526 DOI: 10.1038/Sj.Onc.1202698  0.4
1998 DiGiovanna MP, Lerman MA, Coffey RJ, Muller WJ, Cardiff RD, Stern DF. Active signaling by Neu in transgenic mice. Oncogene. 17: 1877-84. PMID 9778054 DOI: 10.1038/Sj.Onc.1202091  0.359
1998 Burke CL, Stern DF. Activation of Neu (ErbB-2) mediated by disulfide bond-induced dimerization reveals a receptor tyrosine kinase dimer interface Molecular and Cellular Biology. 18: 5371-7379. PMID 9710621 DOI: 10.1128/Mcb.18.9.5371  0.382
1998 Sun Z, Hsiao J, Fay DS, Stern DF. Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint Science. 281: 272-274. PMID 9657725 DOI: 10.1126/Science.281.5374.272  0.669
1998 Riese DJ, Komurasaki T, Plowman GD, Stern DF. Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2. The Journal of Biological Chemistry. 273: 11288-94. PMID 9556621 DOI: 10.1074/Jbc.273.18.11288  0.694
1998 Riese DJ, Stern DF. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 41-8. PMID 9504046 DOI: 10.1002/(Sici)1521-1878(199801)20:1<41::Aid-Bies7>3.0.Co;2-V  0.7
1997 Chang H, Riese DJ, Gilbert W, Stern DF, McMahan UJ. Ligands for ErbB-family receptors encoded by a neuregulin-like gene. Nature. 387: 509-12. PMID 9168114 DOI: 10.1038/387509A0  0.723
1997 Burke CL, Lemmon MA, Coren BA, Engelman DM, Stern DF. Dimerization of the p185neu transmembrane domain is necessary but not sufficient for transformation. Oncogene. 14: 687-96. PMID 9038376 DOI: 10.1038/Sj.Onc.1200873  0.369
1997 Fay DS, Sun Z, Stern DF. Mutations in SPK1/RAD53 that specifically abolish checkpoint but not growth related functions Current Genetics. 31: 97-105. PMID 9021124 DOI: 10.1007/S002940050181  0.692
1997 Kannan S, De Santis M, Lohmeyer M, Riese DJ, Smith GH, Hynes N, Seno M, Brandt R, Bianco C, Persico G, Kenney N, Normanno N, Martinez-Lacaci I, Ciardiello F, Stern DF, et al. Cripto enhances the tyrosine phosphorylation of Shc and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cells. The Journal of Biological Chemistry. 272: 3330-5. PMID 9013573 DOI: 10.1074/Jbc.272.6.3330  0.741
1996 García-Cardeña G, Fan R, Stern DF, Liu J, Sessa WC. Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1. The Journal of Biological Chemistry. 271: 27237-40. PMID 8910295 DOI: 10.1074/Jbc.271.44.27237  0.384
1996 DiGiovanna MP, Carter D, Flynn SD, Stern DF. Functional assay for HER-2/neu demonstrates active signalling in a minority of HER-2/neu-overexpressing invasive human breast tumours. British Journal of Cancer. 74: 802-6. PMID 8795585 DOI: 10.1038/Bjc.1996.439  0.327
1996 Riese DJ, Kim ED, Elenius K, Buckley S, Klagsbrun M, Plowman GD, Stern DF. The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4. The Journal of Biological Chemistry. 271: 20047-52. PMID 8702723 DOI: 10.1074/Jbc.271.33.20047  0.699
1996 Sun Z, Fay DS, Marini F, Foiani M, Stern DF. Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways Genes and Development. 10: 395-406. PMID 8600024 DOI: 10.1101/Gad.10.4.395  0.686
1995 Riese DJ, van Raaij TM, Plowman GD, Andrews GC, Stern DF. The cellular response to neuregulins is governed by complex interactions of the erbB receptor family. Molecular and Cellular Biology. 15: 5770-6. PMID 7565730 DOI: 10.1128/Mcb.15.10.5770  0.718
1993 Zheng P, Fay DS, Burton J, Xiao H, Pinkham JL, Stern DF. SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase Molecular and Cellular Biology. 13: 5829-5842. PMID 8355715 DOI: 10.1128/Mcb.13.9.5829  0.69
1992 Bangalore L, Tanner AJ, Laudano AP, Stern DF. Antiserum raised against a synthetic phosphotyrosine-containing peptide selectively recognizes p185neu/erbB-2 and the epidermal growth factor receptor Proceedings of the National Academy of Sciences of the United States of America. 89: 11637-11641. PMID 1280833 DOI: 10.1073/Pnas.89.23.11637  0.426
1992 Cao H, Bangalore L, Bormann B, Stern D. A subdomain in the transmembrane domain is necessary for p185neu* activation. The Embo Journal. 11: 923-932. DOI: 10.1002/J.1460-2075.1992.Tb05131.X  0.394
1991 Stern DF, Zheng P, Beidler DR, Zerillo C. Spk1, a new kinase from Saccharomyces cerevisiae, phosphorylates proteins on serine, threonine, and tyrosine Molecular and Cellular Biology. 11: 987-1001. PMID 1899289 DOI: 10.1128/Mcb.11.2.987  0.399
1990 Connelly PA, Stern DF. The epidermal growth factor receptor and the product of the neu protooncogene are members of a receptor tyrosine phosphorylation cascade. Proceedings of the National Academy of Sciences of the United States of America. 87: 6054-7. PMID 1974718 DOI: 10.1073/Pnas.87.16.6054  0.455
1990 Filvaroff E, Stern DF, Dotto GP. Tyrosine phosphorylation is an early and specific event involved in primary keratinocyte differentiation. Molecular and Cellular Biology. 10: 1164-73. PMID 1689456 DOI: 10.1128/Mcb.10.3.1164  0.392
1989 Shaw AS, Amrein KE, Hammond C, Stern DF, Sefton BM, Rose JK. The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain. Cell. 59: 627-36. PMID 2582490 DOI: 10.1016/0092-8674(89)90008-1  0.61
1988 Stern DF, Kamps MP, Cao H. Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo. Molecular and Cellular Biology. 8: 3969-73. PMID 2464744 DOI: 10.1128/Mcb.8.9.3969  0.644
1988 Stern DF, Kamps MP. EGF-stimulated tyrosine phosphorylation of p185neu: a potential model for receptor interactions. The Embo Journal. 7: 995-1001. DOI: 10.1002/J.1460-2075.1988.Tb02906.X  0.675
1987 Stern DF, Hare DL, Cecchini MA, Weinberg RA. Construction of a novel oncogene based on synthetic sequences encoding epidermal growth factor. Science (New York, N.Y.). 235: 321-4. PMID 3492043 DOI: 10.1126/science.3492043  0.458
1987 Stern DF, Heffernan PA, Weinberg RA. p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity. Molecular and Cellular Biology. 6: 1729-40. PMID 2878363 DOI: 10.1128/MCB.6.5.1729  0.512
1986 Stern DF, Roberts AB, Roche NS, Sporn MB, Weinberg RA. Differential responsiveness of myc- and ras-transfected cells to growth factors: Selective stimulation of myc-transfected cells by epidermal growth factor Molecular and Cellular Biology. 6: 870-877. PMID 3022135 DOI: 10.1128/Mcb.6.3.870  0.504
1986 Hung MC, Schechter AL, Chevray PYM, Stern DF, Weinberg RA. Molecular cloning of the neu gene: Absence of gross structural alteration in oncogenic alleles Proceedings of the National Academy of Sciences of the United States of America. 83: 261-264. PMID 3001730 DOI: 10.1073/Pnas.83.2.261  0.606
1985 Roberts AB, Anzano MA, Wakefield LM, Roche NS, Stern DF, Sporn MB. Type beta transforming growth factor: a bifunctional regulator of cellular growth. Proceedings of the National Academy of Sciences of the United States of America. 82: 119-23. PMID 3871521 DOI: 10.1073/Pnas.82.1.119  0.306
1985 Drebin JA, Link VC, Stern DF, Weinberg RA, Greene MI. Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies Cell. 41: 695-706. PMID 2860972 DOI: 10.1016/S0092-8674(85)80050-7  0.417
1984 Stern DF, Sefton B. Organization of the IBV genome. Advances in Experimental Medicine and Biology. 173: 11-23. PMID 6331104 DOI: 10.1007/978-1-4615-9373-7_2  0.497
1984 Stern DF, Sefton BM. Coronavirus multiplication: locations of genes for virion proteins on the avian infectious bronchitis virus genome. Journal of Virology. 50: 22-9. PMID 6321790 DOI: 10.1128/jvi.50.1.22-29.1984  0.534
1982 Stern DF, Sefton BM. Coronavirus proteins: structure and function of the oligosaccharides of the avian infectious bronchitis virus glycoproteins. Journal of Virology. 44: 804-12. PMID 6294330 DOI: 10.1128/jvi.44.3.804-812.1982  0.52
1982 Stern DF, Sefton BM. Coronavirus proteins: biogenesis of avian infectious bronchitis virus virion proteins. Journal of Virology. 44: 794-803. PMID 6294329 DOI: 10.1128/jvi.44.3.794-803.1982  0.518
1982 Stern DF, Sefton BM. Synthesis of coronavirus mRNAs: kinetics of inactivation of infectious bronchitis virus RNA synthesis by UV light. Journal of Virology. 42: 755-9. PMID 6283182 DOI: 10.1128/jvi.42.2.755-759.1982  0.502
1982 Stern DF, Burgess L, Sefton BM. Structural analysis of virion proteins of the avian coronavirus infectious bronchitis virus. Journal of Virology. 42: 208-19. PMID 6283141 DOI: 10.1128/jvi.42.1.208-219.1982  0.525
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