Gosia Trynka - Publications

Affiliations: 
Genetics Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Bonder MJ, Tigchelaar EF, Cai X, Trynka G, Cenit MC, Hrdlickova B, Zhong H, Vatanen T, Gevers D, Wijmenga C, Wang Y, Zhernakova A. The influence of a short-term gluten-free diet on the human gut microbiome. Genome Medicine. 8: 45. PMID 27102333 DOI: 10.1186/S13073-016-0295-Y  0.48
2015 Gutierrez-Achury J, Zorro MM, Ricaño-Ponce I, Zhernakova DV, Diogo D, Raychaudhuri S, Franke L, Trynka G, Wijmenga C, Zhernakova A. Functional implications of disease-specific variants in loci jointly associated to coeliac disease and rheumatoid arthritis. Human Molecular Genetics. PMID 26546613 DOI: 10.1093/Hmg/Ddv455  0.48
2015 Hayes JE, Trynka G, Vijai J, Offit K, Raychaudhuri S, Klein RJ. Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements. Plos One. 10: e0139360. PMID 26422229 DOI: 10.1371/Journal.Pone.0139360  0.48
2015 Finucane HK, Bulik-Sullivan B, Gusev A, Trynka G, Reshef Y, Loh PR, Anttila V, Xu H, Zang C, Farh K, Ripke S, Day FR, et al. Partitioning heritability by functional annotation using genome-wide association summary statistics. Nature Genetics. PMID 26414678 DOI: 10.1038/Ng.3404  0.48
2015 Trynka G, Westra HJ, Slowikowski K, Hu X, Xu H, Stranger BE, Klein RJ, Han B, Raychaudhuri S. Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci. American Journal of Human Genetics. 97: 139-52. PMID 26140449 DOI: 10.1016/J.Ajhg.2015.05.016  0.48
2015 Franke L, El Bannoudi H, Jansen DT, Kok K, Trynka G, Diogo D, Swertz M, Fransen K, Knevel R, Gutierrez-Achury J, Ärlestig L, Greenberg JD, Kremer J, Pappas DA, Kanterakis A, et al. Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes. European Journal of Human Genetics : Ejhg. PMID 25966632 DOI: 10.1038/Ejhg.2015.95  0.48
2015 Coleman C, Quinn EM, Ryan AW, Conroy J, Trimble V, Mahmud N, Kennedy N, Corvin AP, Morris DW, Donohoe G, O'Morain C, MacMathuna P, Byrnes V, Kiat C, Trynka G, et al. Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci. European Journal of Human Genetics : Ejhg. PMID 25920553 DOI: 10.1038/Ejhg.2015.87  0.48
2015 Gutierrez-Achury J, Zhernakova A, Pulit SL, Trynka G, Hunt KA, Romanos J, Raychaudhuri S, van Heel DA, Wijmenga C, de Bakker PI. Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease. Nature Genetics. 47: 577-8. PMID 25894500 DOI: 10.1038/Ng.3268  0.48
2015 Palles C, Chegwidden L, Li X, Findlay JM, Farnham G, Castro Giner F, Peppelenbosch MP, Kovac M, Adams CL, Prenen H, Briggs S, Harrison R, Sanders S, MacDonald D, Haigh C, ... ... Trynka G, et al. Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus. Gastroenterology. 148: 367-78. PMID 25447851 DOI: 10.1053/J.Gastro.2014.10.041  0.48
2014 Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E, Kähler AK, Hultman CM, Purcell SM, et al. Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. American Journal of Human Genetics. 95: 535-52. PMID 25439723 DOI: 10.1016/J.Ajhg.2014.10.004  0.48
2014 Gockel I, Becker J, Wouters MM, Niebisch S, Gockel HR, Hess T, Ramonet D, Zimmermann J, Vigo AG, Trynka G, de León AR, de la Serna JP, Urcelay E, Kumar V, Franke L, et al. Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. Nature Genetics. 46: 901-4. PMID 24997987 DOI: 10.1038/Ng.3029  0.48
2014 Hu X, Kim H, Raj T, Brennan PJ, Trynka G, Teslovich N, Slowikowski K, Chen WM, Onengut S, Baecher-Allan C, De Jager PL, Rich SS, Stranger BE, Brenner MB, Raychaudhuri S. Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells. Plos Genetics. 10: e1004404. PMID 24968232 DOI: 10.1371/Journal.Pgen.1004404  0.48
2014 Laayouni H, Oosting M, Luisi P, Ioana M, Alonso S, Ricaño-Ponce I, Trynka G, Zhernakova A, Plantinga TS, Cheng SC, van der Meer JW, Popp R, Sood A, Thelma BK, Wijmenga C, et al. Convergent evolution in European and Rroma populations reveals pressure exerted by plague on Toll-like receptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 2668-73. PMID 24550294 DOI: 10.1073/Pnas.1317723111  0.48
2014 Okada Y, Diogo D, Greenberg JD, Mouassess F, Achkar WA, Fulton RS, Denny JC, Gupta N, Mirel D, Gabriel S, Li G, Kremer JM, Pappas DA, Carroll RJ, Eyler AE, ... Trynka G, et al. Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene. Plos One. 9: e87645. PMID 24520335 DOI: 10.1371/Journal.Pone.0087645  0.48
2014 Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, et al. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 506: 376-81. PMID 24390342 DOI: 10.1038/Nature12873  0.48
2014 Almeida R, Ricaño-Ponce I, Kumar V, Deelen P, Szperl A, Trynka G, Gutierrez-Achury J, Kanterakis A, Westra HJ, Franke L, Swertz MA, Platteel M, Bilbao JR, Barisani D, Greco L, et al. Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant. Human Molecular Genetics. 23: 2481-9. PMID 24334606 DOI: 10.1093/Hmg/Ddt619  0.48
2014 Romanos J, Rosén A, Kumar V, Trynka G, Franke L, Szperl A, Gutierrez-Achury J, van Diemen CC, Kanninga R, Jankipersadsing SA, Steck A, Eisenbarth G, van Heel DA, Cukrowska B, Bruno V, et al. Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants. Gut. 63: 415-22. PMID 23704318 DOI: 10.1136/Gutjnl-2012-304110  0.48
2013 Trynka G, Raychaudhuri S. Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases. Current Opinion in Genetics & Development. 23: 635-41. PMID 24287333 DOI: 10.1016/J.Gde.2013.10.009  0.48
2013 Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Trynka G, Raj T, Mirkov MU, Canhao H, Ikari K, Terao C, Okada Y, Wedrén S, Askling J, Yamanaka H, et al. Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis. Plos Genetics. 9: e1003394. PMID 23555300 DOI: 10.1371/Journal.Pgen.1003394  0.48
2013 Faraco J, Lin L, Kornum BR, Kenny EE, Trynka G, Einen M, Rico TJ, Lichtner P, Dauvilliers Y, Arnulf I, Lecendreux M, Javidi S, Geisler P, Mayer G, Pizza F, et al. ImmunoChip study implicates antigen presentation to T cells in narcolepsy. Plos Genetics. 9: e1003270. PMID 23459209 DOI: 10.1371/Journal.Pgen.1003270  0.48
2013 Trynka G, Sandor C, Han B, Xu H, Stranger BE, Liu XS, Raychaudhuri S. Chromatin marks identify critical cell types for fine mapping complex trait variants Nature Genetics. 45: 124-130. PMID 23263488 DOI: 10.1038/Ng.2504  0.48
2012 Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, ... Trynka G, et al. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nature Genetics. 44: 1336-40. PMID 23143596 DOI: 10.1038/Ng.2462  0.48
2012 Stahl EA, Wegmann D, Trynka G, Gutierrez-Achury J, Do R, Voight BF, Kraft P, Chen R, Kallberg HJ, Kurreeman FA, Kathiresan S, Wijmenga C, Gregersen PK, et al. Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis. Nature Genetics. 44: 483-9. PMID 22446960 DOI: 10.1038/Ng.2232  0.48
2012 Hunt KA, Smyth DJ, Balschun T, Ban M, Mistry V, Ahmad T, Anand V, Barrett JC, Bhaw-Rosun L, Bockett NA, Brand OJ, Brouwer E, Concannon P, Cooper JD, Dias KR, ... ... Trynka G, et al. Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry. Nature Genetics. 44: 3-5. PMID 22200769 DOI: 10.1038/Ng.1037  0.48
2011 Trynka G, Hunt KA, Bockett NA, Romanos J, Mistry V, Szperl A, Bakker SF, Bardella MT, Bhaw-Rosun L, Castillejo G, de la Concha EG, de Almeida RC, Dias KR, van Diemen CC, Dubois PC, et al. Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nature Genetics. 43: 1193-201. PMID 22057235 DOI: 10.1038/Ng.998  0.48
2011 Fehrmann RS, Jansen RC, Veldink JH, Westra HJ, Arends D, Bonder MJ, Fu J, Deelen P, Groen HJ, Smolonska A, Weersma RK, Hofstra RM, Buurman WA, Rensen S, Wolfs MG, ... ... Trynka G, et al. Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. Plos Genetics. 7: e1002197. PMID 21829388 DOI: 10.1371/Journal.Pgen.1002197  0.48
2011 Szperl A, Ricaño-Ponce I, Li J, Deelen P, Kanterakis A, Plagnol V, van Dijk F, Westra H, Trynka G, Mulder C, Swertz M, Wijmenga C, Zheng HC. Exome sequencing in a family segregating for celiac disease Clinical Genetics. 80: 138-147. PMID 21627641 DOI: 10.1111/J.1399-0004.2011.01714.X  0.48
2011 Zhernakova A, Stahl EA, Trynka G, Raychaudhuri S, Festen EA, Franke L, Westra HJ, Fehrmann RS, Kurreeman FA, Thomson B, Gupta N, Romanos J, McManus R, Ryan AW, Turner G, et al. Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. Plos Genetics. 7: e1002004. PMID 21383967 DOI: 10.1371/Journal.Pgen.1002004  0.48
2011 Festen EA, Goyette P, Green T, Boucher G, Beauchamp C, Trynka G, Dubois PC, Lagacé C, Stokkers PC, Hommes DW, Barisani D, Palmieri O, Annese V, van Heel DA, Weersma RK, et al. A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease. Plos Genetics. 7: e1001283. PMID 21298027 DOI: 10.1371/Journal.Pgen.1001283  0.48
2010 Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, et al. Multiple common variants for celiac disease influencing immune gene expression. Nature Genetics. 42: 295-302. PMID 20190752 DOI: 10.1038/Ng.543  0.48
2009 Heap GA, Trynka G, Jansen RC, Bruinenberg M, Swertz MA, Dinesen LC, Hunt KA, Wijmenga C, Vanheel DA, Franke L. Complex nature of SNP genotype effects on gene expression in primary human leucocytes. Bmc Medical Genomics. 2: 1. PMID 19128478 DOI: 10.1186/1755-8794-2-1  0.48
2008 Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, Gwilliam R, Takeuchi F, McLaren WM, Holmes GK, Howdle PD, ... ... Trynka G, et al. Newly identified genetic risk variants for celiac disease related to the immune response. Nature Genetics. 40: 395-402. PMID 18311140 DOI: 10.1038/Ng.102  0.48
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