Harm-Jan Westra - Publications

Affiliations: 
Genetics Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States 

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Amariuta T, Luo Y, Gazal S, Davenport EE, van de Geijn B, Ishigaki K, Westra HJ, Teslovich N, Okada Y, Yamamoto K, Price AL, Raychaudhuri S. IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors. American Journal of Human Genetics. PMID 31006511 DOI: 10.1016/j.ajhg.2019.03.012  0.36
2018 van der Wijst MGP, de Vries DH, Brugge H, Westra HJ, Franke L. An integrative approach for building personalized gene regulatory networks for precision medicine. Genome Medicine. 10: 96. PMID 30567569 DOI: 10.1186/s13073-018-0608-4  1
2018 Davenport EE, Amariuta T, Gutierrez-Arcelus M, Slowikowski K, Westra HJ, Luo Y, Shen C, Rao DA, Zhang Y, Pearson S, von Schack D, Beebe JS, Bing N, John S, Vincent MS, et al. Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial. Genome Biology. 19: 168. PMID 30340504 DOI: 10.1186/s13059-018-1560-8  0.36
2018 Westra HJ, Martínez-Bonet M, Onengut-Gumuscu S, Lee A, Luo Y, Teslovich N, Worthington J, Martin J, Huizinga T, Klareskog L, Rantapaa-Dahlqvist S, Chen WM, Quinlan A, Todd JA, Eyre S, et al. Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. Nature Genetics. PMID 30224649 DOI: 10.1038/s41588-018-0216-7  1
2018 Li G, Martínez-Bonet M, Wu D, Yang Y, Cui J, Nguyen HN, Cunin P, Levescot A, Bai M, Westra HJ, Okada Y, Brenner MB, Raychaudhuri S, Hendrickson EA, Maas RL, et al. High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction. Nature Genetics. PMID 30013183 DOI: 10.1038/s41588-018-0159-z  0.36
2017 Kasela S, Kisand K, Tserel L, Kaleviste E, Remm A, Fischer K, Esko T, Westra HJ, Fairfax BP, Makino S, Knight JC, Franke L, Metspalu A, Peterson P, Milani L. Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells. Plos Genetics. 13: e1006643. PMID 28248954 DOI: 10.1371/journal.pgen.1006643  1
2017 Zych K, Snoek BL, Elvin M, Rodriguez M, Van der Velde KJ, Arends D, Westra HJ, Swertz MA, Poulin G, Kammenga JE, Breitling R, Jansen RC, Li Y. reGenotyper: Detecting mislabeled samples in genetic data. Plos One. 12: e0171324. PMID 28192439 DOI: 10.1371/journal.pone.0171324  1
2016 Zhernakova DV, Deelen P, Vermaat M, van Iterson M, van Galen M, Arindrarto W, van 't Hof P, Mei H, van Dijk F, Westra HJ, Bonder MJ, van Rooij J, Verkerk M, Jhamai PM, Moed M, et al. Identification of context-dependent expression quantitative trait loci in whole blood. Nature Genetics. PMID 27918533 DOI: 10.1038/ng.3737  1
2016 Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Westra HJ, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 1591. PMID 27898078 DOI: 10.1038/ng1216-1587b  1
2016 van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I, Eijgelsheim M, Sotoodehnia N, Hayward C, Sorice R, Meirelles O, Lyytikäinen LP, Polašek O, ... ... Westra HJ, et al. 52 Genetic Loci Influencing Myocardial Mass. Journal of the American College of Cardiology. 68: 1435-48. PMID 27659466 DOI: 10.1016/j.jacc.2016.07.729  0.01
2016 Okbay A, Baselmans BM, Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Westra HJ, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 970. PMID 27463399 DOI: 10.1038/ng0816-970c  1
2016 Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Westra HJ, et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. PMID 27089181 DOI: 10.1038/ng.3552  1
2016 Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J, Han B, Park YR, Raychaudhuri S, Pouget JG, Hübenthal M, Folseraas T, Wang Y, Esko T, Metspalu A, Westra HJ, et al. Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nature Genetics. PMID 26974007 DOI: 10.1038/ng.3528  1
2016 Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman ÅK, ... ... Westra HJ, et al. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications. 7: 10495. PMID 26833246 DOI: 10.1038/ncomms10495  1
2015 Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T, Ramos YF, ... ... Westra HJ, et al. The transcriptional landscape of age in human peripheral blood. Nature Communications. 6: 8570. PMID 26490707 DOI: 10.1038/ncomms9570  1
2015 Kogelman LJ, Zhernakova DV, Westra HJ, Cirera S, Fredholm M, Franke L, Kadarmideen HN. An integrative systems genetics approach reveals potential causal genes and pathways related to obesity. Genome Medicine. 7: 105. PMID 26482556 DOI: 10.1186/s13073-015-0229-0  1
2015 Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... Westra HJ, et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 11: e1005378. PMID 26426971 DOI: 10.1371/journal.pgen.1005378  1
2015 Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, Abedian S, Cheon JH, Cho J, Daryani NE, Franke L, ... ... Westra HJ, et al. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nature Genetics. PMID 26192919 DOI: 10.1038/ng.3359  1
2015 Trynka G, Westra HJ, Slowikowski K, Hu X, Xu H, Stranger BE, Klein RJ, Han B, Raychaudhuri S. Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci. American Journal of Human Genetics. 97: 139-52. PMID 26140449 DOI: 10.1016/j.ajhg.2015.05.016  1
2015 Draisma HH, Pool R, Kobl M, Jansen R, Petersen AK, Vaarhorst AA, Yet I, Haller T, Demirkan A, Esko T, Zhu G, Böhringer S, Beekman M, van Klinken JB, Römisch-Margl W, ... ... Westra HJ, et al. Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature Communications. 6: 7208. PMID 26068415 DOI: 10.1038/ncomms8208  1
2015 Surakka I, Horikoshi M, Mägi R, Sarin AP, Mahajan A, Lagou V, Marullo L, Ferreira T, Miraglio B, Timonen S, Kettunen J, Pirinen M, Karjalainen J, Thorleifsson G, Hägg S, ... ... Westra HJ, et al. The impact of low-frequency and rare variants on lipid levels. Nature Genetics. 47: 589-97. PMID 25961943 DOI: 10.1038/ng.3300  1
2015 Westra HJ, Arends D, Esko T, Peters MJ, Schurmann C, Schramm K, Kettunen J, Yaghootkar H, Fairfax BP, Andiappan AK, Li Y, Fu J, Karjalainen J, Platteel M, Visschedijk M, et al. Cell Specific eQTL Analysis without Sorting Cells. Plos Genetics. 11: e1005223. PMID 25955312 DOI: 10.1371/journal.pgen.1005223  1
2015 Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der Meer P, Tanaka T, ... ... Westra HJ, et al. Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nature Communications. 6: 6542. PMID 25817829 DOI: 10.1038/ncomms7542  1
2015 Jin P, Andiappan AK, Quek JM, Lee B, Au B, Sio YY, Irwanto A, Schurmann C, Grabe HJ, Suri BK, Matta SA, Westra HJ, Franke L, Esko T, Sun L, et al. A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis. The Journal of Allergy and Clinical Immunology. 135: 1486-1493.e8. PMID 25649076 DOI: 10.1016/j.jaci.2014.12.1870  1
2015 Pers TH, Karjalainen JM, Chan Y, Westra HJ, Wood AR, Yang J, Lui JC, Vedantam S, Gustafsson S, Esko T, Frayling T, Speliotes EK, Boehnke M, Raychaudhuri S, et al. Biological interpretation of genome-wide association studies using predicted gene functions. Nature Communications. 6: 5890. PMID 25597830 DOI: 10.1038/ncomms6890  1
2015 Fehrmann RS, Karjalainen JM, Krajewska M, Westra HJ, Maloney D, Simeonov A, Pers TH, Hirschhorn JN, Jansen RC, Schultes EA, van Haagen HH, de Vries EG, te Meerman GJ, Wijmenga C, van Vugt MA, et al. Gene expression analysis identifies global gene dosage sensitivity in cancer. Nature Genetics. 47: 115-25. PMID 25581432 DOI: 10.1038/ng.3173  1
2015 Kumar V, Gutierrez-Achury J, Kanduri K, Almeida R, Hrdlickova B, Zhernakova DV, Westra HJ, Karjalainen J, Ricaño-Ponce I, Li Y, Stachurska A, Tigchelaar EF, Abdulahad WH, Lähdesmäki H, Hofker MH, et al. Systematic annotation of celiac disease loci refines pathological pathways and suggests a genetic explanation for increased interferon-gamma levels. Human Molecular Genetics. 24: 397-409. PMID 25190711 DOI: 10.1093/hmg/ddu453  1
2015 Andiappan AK, Narayanan S, Myers RA, Lee B, Nieuwenhuis MA, Nardin A, Park CS, Shin HD, Kim JH, Westra HJ, Franke L, Esko T, Metspalu A, Teo YY, Saw SM, et al. Genetic variants of inducible costimulator are associated with allergic asthma susceptibility. The Journal of Allergy and Clinical Immunology. 135: 556-8. PMID 25109803 DOI: 10.1016/j.jaci.2014.06.028  1
2014 Deelen P, Bonder MJ, van der Velde KJ, Westra HJ, Winder E, Hendriksen D, Franke L, Swertz MA. Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration. Bmc Research Notes. 7: 901. PMID 25495213 DOI: 10.1186/1756-0500-7-901  1
2014 Pierce BL, Tong L, Chen LS, Rahaman R, Argos M, Jasmine F, Roy S, Paul-Brutus R, Westra HJ, Franke L, Esko T, Zaman R, Islam T, Rahman M, Baron JA, et al. Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians. Plos Genetics. 10: e1004818. PMID 25474530 DOI: 10.1371/journal.pgen.1004818  1
2014 Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der Meer P, Tanaka T, ... ... Westra HJ, et al. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nature Communications. 5: 4926. PMID 25352340 DOI: 10.1038/ncomms5926  1
2014 Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, ... ... Westra HJ, et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics. 46: 1173-86. PMID 25282103 DOI: 10.1038/ng.3097  1
2014 Hemani G, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Yang J, Gibson G, Martin NG, Metspalu A, Franke L, Montgomery GW, Visscher PM, Powell JE. Hemani et al. reply. Nature. 514: E5-6. PMID 25279929 DOI: 10.1038/nature13692  1
2014 Gockel I, Becker J, Wouters MM, Niebisch S, Gockel HR, Hess T, Ramonet D, Zimmermann J, Vigo AG, Trynka G, de León AR, de la Serna JP, Urcelay E, Kumar V, Franke L, ... Westra HJ, et al. Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. Nature Genetics. 46: 901-4. PMID 24997987 DOI: 10.1038/ng.3029  1
2014 Cozen W, Timofeeva MN, Li D, Diepstra A, Hazelett D, Delahaye-Sourdeix M, Edlund CK, Franke L, Rostgaard K, Van Den Berg DJ, Cortessis VK, Smedby KE, Glaser SL, Westra HJ, Robison LL, et al. A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus. Nature Communications. 5: 3856. PMID 24920014 DOI: 10.1038/ncomms4856  1
2014 Deelen P, Menelaou A, van Leeuwen EM, Kanterakis A, van Dijk F, Medina-Gomez C, Francioli LC, Hottenga JJ, Karssen LC, Estrada K, Kreiner-Møller E, Rivadeneira F, van Setten J, Gutierrez-Achury J, Westra HJ, et al. Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'. European Journal of Human Genetics : Ejhg. 22: 1321-6. PMID 24896149 DOI: 10.1038/ejhg.2014.19  1
2014 Westra HJ, Franke L. From genome to function by studying eQTLs. Biochimica Et Biophysica Acta. 1842: 1896-1902. PMID 24798236 DOI: 10.1016/j.bbadis.2014.04.024  1
2014 Li H, Chan L, Bartuzi P, Melton SD, Weber A, Ben-Shlomo S, Varol C, Raetz M, Mao X, Starokadomskyy P, van Sommeren S, Mokadem M, Schneider H, Weisberg R, Westra HJ, et al. Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer. Gastroenterology. 147: 184-195.e3. PMID 24727021 DOI: 10.1053/j.gastro.2014.04.007  1
2014 Fransen K, van Sommeren S, Westra HJ, Veenstra M, Lamberts LE, Modderman R, Dijkstra G, Fu J, Wijmenga C, Franke L, Weersma RK, van Diemen CC. Correlation of genetic risk and messenger RNA expression in a Th17/IL23 pathway analysis in inflammatory bowel disease. Inflammatory Bowel Diseases. 20: 777-82. PMID 24662057 DOI: 10.1097/MIB.0000000000000013  1
2014 Hemani G, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Yang J, Gibson G, Martin NG, Metspalu A, Franke L, Montgomery GW, Visscher PM, Powell JE. Detection and replication of epistasis influencing transcription in humans. Nature. 508: 249-53. PMID 24572353 DOI: 10.1038/nature13005  1
2014 Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, ... ... Westra HJ, et al. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 506: 376-81. PMID 24390342 DOI: 10.1038/nature12873  1
2014 Almeida R, Ricaño-Ponce I, Kumar V, Deelen P, Szperl A, Trynka G, Gutierrez-Achury J, Kanterakis A, Westra HJ, Franke L, Swertz MA, Platteel M, Bilbao JR, Barisani D, Greco L, et al. Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant. Human Molecular Genetics. 23: 2481-9. PMID 24334606 DOI: 10.1093/hmg/ddt619  1
2013 Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE, Zhernakova A, Zhernakova DV, Veldink JH, Van den Berg LH, Karjalainen J, et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nature Genetics. 45: 1238-43. PMID 24013639 DOI: 10.1038/ng.2756  1
2013 Zhernakova DV, de Klerk E, Westra HJ, Mastrokolias A, Amini S, Ariyurek Y, Jansen R, Penninx BW, Hottenga JJ, Willemsen G, de Geus EJ, Boomsma DI, Veldink JH, van den Berg LH, Wijmenga C, et al. DeepSAGE reveals genetic variants associated with alternative polyadenylation and expression of coding and non-coding transcripts. Plos Genetics. 9: e1003594. PMID 23818875 DOI: 10.1371/journal.pgen.1003594  1
2013 Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, et al. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (New York, N.Y.). 340: 1467-71. PMID 23722424 DOI: 10.1126/science.1235488  1
2013 Trouw LA, Daha N, Kurreeman FA, Böhringer S, Goulielmos GN, Westra HJ, Zhernakova A, Franke L, Stahl EA, Levarht EW, Stoeken-Rijsbergen G, Verduijn W, Roos A, Li Y, Houwing-Duistermaat JJ, et al. Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis. Clinical and Experimental Immunology. 173: 76-83. PMID 23607884 DOI: 10.1111/cei.12097  1
2013 den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, et al. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics. 45: 621-31. PMID 23583979 DOI: 10.1038/ng.2610  1
2013 Cvejic A, Haer-Wigman L, Stephens JC, Kostadima M, Smethurst PA, Frontini M, van den Akker E, Bertone P, Bielczyk-MaczyÅ„ska E, Farrow S, Fehrmann RS, Gray A, de Haas M, Haver VG, Jordan G, ... ... Westra HJ, et al. SMIM1 underlies the Vel blood group and influences red blood cell traits. Nature Genetics. 45: 542-5. PMID 23563608 DOI: 10.1038/ng.2603  1
2013 Knevel R, Krabben A, Wilson AG, Brouwer E, Leijsma MK, Lindqvist E, de Rooy DP, Daha NA, van der Linden MP, Tsonaka S, Zhernakova A, Westra HJ, Franke L, Houwing-Duistermaat JJ, Toes RE, et al. A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis. Arthritis and Rheumatism. 65: 582-9. PMID 23440692 DOI: 10.1002/art.37808  1
2013 Kumar V, Westra HJ, Karjalainen J, Zhernakova DV, Esko T, Hrdlickova B, Almeida R, Zhernakova A, Reinmaa E, Võsa U, Hofker MH, Fehrmann RS, Fu J, Withoff S, Metspalu A, et al. Human disease-associated genetic variation impacts large intergenic non-coding RNA expression. Plos Genetics. 9: e1003201. PMID 23341781 DOI: 10.1371/journal.pgen.1003201  1
2012 van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan ST, Voss K, Weichenberger CX, Albers CA, ... ... Westra HJ, et al. Seventy-five genetic loci influencing the human red blood cell. Nature. 492: 369-75. PMID 23222517 DOI: 10.1038/nature11677  1
2012 Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, ... ... Westra HJ, et al. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nature Genetics. 44: 1336-40. PMID 23143596 DOI: 10.1038/ng.2462  1
2012 de Boer RA, Verweij N, van Veldhuisen DJ, Westra HJ, Bakker SJ, Gansevoort RT, Muller Kobold AC, van Gilst WH, Franke L, Mateo Leach I, van der Harst P. A genome-wide association study of circulating galectin-3. Plos One. 7: e47385. PMID 23056639 DOI: 10.1371/journal.pone.0047385  1
2012 Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, ... ... Westra HJ, et al. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. American Journal of Human Genetics. 91: 744-53. PMID 23022100 DOI: 10.1016/j.ajhg.2012.08.021  1
2012 Fu J, Wolfs MG, Deelen P, Westra HJ, Fehrmann RS, Te Meerman GJ, Buurman WA, Rensen SS, Groen HJ, Weersma RK, van den Berg LH, Veldink J, Ophoff RA, Snieder H, van Heel D, et al. Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. Plos Genetics. 8: e1002431. PMID 22275870 DOI: 10.1371/journal.pgen.1002431  1
2011 Johnson T, Gaunt TR, Newhouse SJ, Padmanabhan S, Tomaszewski M, Kumari M, Morris RW, Tzoulaki I, O'Brien ET, Poulter NR, Sever P, Shields DC, Thom S, Wannamethee SG, Whincup PH, ... ... Westra HJ, et al. Blood pressure loci identified with a gene-centric array. American Journal of Human Genetics. 89: 688-700. PMID 22100073 DOI: 10.1016/j.ajhg.2011.10.013  1
2011 Sampietro ML, Trompet S, Verschuren JJ, Talens RP, Deelen J, Heijmans BT, de Winter RJ, Tio RA, Doevendans PA, Ganesh SK, Nabel EG, Westra HJ, Franke L, van den Akker EB, Westendorp RG, et al. A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention. Human Molecular Genetics. 20: 4748-57. PMID 21878436 DOI: 10.1093/hmg/ddr389  1
2011 Fehrmann RS, Jansen RC, Veldink JH, Westra HJ, Arends D, Bonder MJ, Fu J, Deelen P, Groen HJ, Smolonska A, Weersma RK, Hofstra RM, Buurman WA, Rensen S, Wolfs MG, et al. Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. Plos Genetics. 7: e1002197. PMID 21829388 DOI: 10.1371/journal.pgen.1002197  1
2011 Westra HJ, Jansen RC, Fehrmann RS, te Meerman GJ, van Heel D, Wijmenga C, Franke L. MixupMapper: correcting sample mix-ups in genome-wide datasets increases power to detect small genetic effects. Bioinformatics (Oxford, England). 27: 2104-11. PMID 21653519 DOI: 10.1093/bioinformatics/btr323  1
2011 Szperl A, Ricaño-Ponce I, Li J, Deelen P, Kanterakis A, Plagnol V, van Dijk F, Westra H, Trynka G, Mulder C, Swertz M, Wijmenga C, Zheng HC. Exome sequencing in a family segregating for celiac disease Clinical Genetics. 80: 138-147. PMID 21627641 DOI: 10.1111/j.1399-0004.2011.01714.x  1
2011 Hrdlickova B, Westra HJ, Franke L, Wijmenga C. Celiac disease: moving from genetic associations to causal variants. Clinical Genetics. 80: 203-313. PMID 21595655 DOI: 10.1111/j.1399-0004.2011.01707.x  1
2011 Zhernakova A, Stahl EA, Trynka G, Raychaudhuri S, Festen EA, Franke L, Westra HJ, Fehrmann RS, Kurreeman FA, Thomson B, Gupta N, Romanos J, McManus R, Ryan AW, Turner G, et al. Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. Plos Genetics. 7: e1002004. PMID 21383967 DOI: 10.1371/journal.pgen.1002004  1
2011 Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, ... ... Westra HJ, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genetics. 43: 246-52. PMID 21297633 DOI: 10.1038/ng.764  1
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