| Year |
Citation |
Score |
| 2024 |
Kim T, Martínez-Bonet M, Wang Q, Hackert N, Sparks JA, Baglaenko Y, Koh B, Darbousset R, Laza-Briviesca R, Chen X, Aguiar VRC, Chiu DJ, Westra HJ, Gutierrez-Arcelus M, Weirauch MT, et al. Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development. Nature Communications. 15: 2150. PMID 38459032 DOI: 10.1038/s41467-024-46457-8 |
0.515 |
|
| 2024 |
Vochteloo M, Deelen P, Vink B, Tsai EA, Runz H, Andreu-Sánchez S, Fu J, Zhernakova A, Westra HJ, Franke L. PICALO: principal interaction component analysis for the identification of discrete technical, cell-type, and environmental factors that mediate eQTLs. Genome Biology. 25: 29. PMID 38254182 DOI: 10.1186/s13059-023-03151-0 |
0.783 |
|
| 2023 |
Li S, Schmid KT, de Vries DH, Korshevniuk M, Losert C, Oelen R, van Blokland IV, Groot HE, Swertz MA, van der Harst P, Westra HJ, van der Wijst MGP, Heinig M, Franke L. Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data. Genome Biology. 24: 80. PMID 37072791 DOI: 10.1186/s13059-023-02897-x |
0.692 |
|
| 2023 |
de Klein N, Tsai EA, Vochteloo M, Baird D, Huang Y, Chen CY, van Dam S, Oelen R, Deelen P, Bakker OB, El Garwany O, Ouyang Z, Marshall EE, Zavodszky MI, van Rheenen W, ... ... Westra HJ, et al. Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases. Nature Genetics. PMID 36823318 DOI: 10.1038/s41588-023-01300-6 |
0.774 |
|
| 2023 |
Boulogne F, Claus LR, Wiersma H, Oelen R, Schukking F, de Klein N, Li S, Westra HJ, van der Zwaag B, van Reekum F, Sierks D, Schönauer R, Li Z, Bijlsma EK, Bos WJW, et al. KidneyNetwork: using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease. European Journal of Human Genetics : Ejhg. PMID 36807342 DOI: 10.1038/s41431-023-01296-x |
0.786 |
|
| 2022 |
Oelen R, de Vries DH, Brugge H, Gordon MG, Vochteloo M, Ye CJ, Westra HJ, Franke L, van der Wijst MGP. Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure. Nature Communications. 13: 3267. PMID 35672358 DOI: 10.1038/s41467-022-30893-5 |
0.681 |
|
| 2022 |
van Rheenen W, van der Spek RAA, Bakker MK, van Vugt JJFA, Hop PJ, Zwamborn RAJ, de Klein N, Westra HJ, Bakker OB, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, et al. Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics. PMID 35102318 DOI: 10.1038/s41588-022-01020-3 |
0.779 |
|
| 2021 |
van Rheenen W, van der Spek RAA, Bakker MK, van Vugt JJFA, Hop PJ, Zwamborn RAJ, de Klein N, Westra HJ, Bakker OB, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, et al. Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics. 53: 1636-1648. PMID 34873335 DOI: 10.1038/s41588-021-00973-1 |
0.8 |
|
| 2021 |
Võsa U, Claringbould A, Westra HJ, Bonder MJ, Deelen P, Zeng B, Kirsten H, Saha A, Kreuzhuber R, Yazar S, Brugge H, Oelen R, de Vries DH, van der Wijst MGP, Kasela S, et al. Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nature Genetics. PMID 34475573 DOI: 10.1038/s41588-021-00913-z |
0.833 |
|
| 2021 |
Hemani G, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Yang J, Gibson G, Martin NG, Metspalu A, Franke L, Montgomery GW, Visscher PM, Powell JE. Retraction Note: Detection and replication of epistasis influencing transcription in humans. Nature. 596: 306. PMID 34381240 DOI: 10.1038/s41586-021-03766-y |
0.582 |
|
| 2021 |
Hemani G, Powell JE, Wang H, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Martin NG, Metspalu A, Franke L, Montgomery GW, Goddard ME, Gibson G, Yang J, et al. Phantom epistasis between unlinked loci. Nature. 596: E1-E3. PMID 34381229 DOI: 10.1038/s41586-021-03765-z |
0.657 |
|
| 2021 |
Pellegrino-Coppola D, Claringbould A, Stutvoet M, Boomsma DI, Ikram MA, Slagboom PE, Westra HJ, Franke L. Correction for both common and rare cell types in blood is important to identify genes that correlate with age. Bmc Genomics. 22: 184. PMID 33722199 DOI: 10.1186/s12864-020-07344-w |
0.624 |
|
| 2021 |
Hu S, Uniken Venema WT, Westra HJ, Vich Vila A, Barbieri R, Voskuil MD, Blokzijl T, Jansen BH, Li Y, Daly MJ, Xavier RJ, Dijkstra G, Festen EA, Weersma RK. Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease. Nature Communications. 12: 1122. PMID 33602935 DOI: 10.1038/s41467-021-21458-z |
0.543 |
|
| 2021 |
Kurilshikov A, Medina-Gomez C, Bacigalupe R, Radjabzadeh D, Wang J, Demirkan A, Le Roy CI, Raygoza Garay JA, Finnicum CT, Liu X, Zhernakova DV, Bonder MJ, Hansen TH, Frost F, Rühlemann MC, ... ... Westra HJ, et al. Large-scale association analyses identify host factors influencing human gut microbiome composition. Nature Genetics. PMID 33462485 DOI: 10.1038/s41588-020-00763-1 |
0.783 |
|
| 2020 |
Folkersen L, Gustafsson S, Wang Q, Hansen DH, Hedman ÅK, Schork A, Page K, Zhernakova DV, Wu Y, Peters J, Eriksson N, Bergen SE, Boutin TS, Bretherick AD, Enroth S, ... ... Westra HJ, et al. Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. Nature Metabolism. 2: 1135-1148. PMID 33067605 DOI: 10.1038/s42255-020-00287-2 |
0.628 |
|
| 2020 |
van der Graaf A, Claringbould A, Rimbert A, Westra HJ, Li Y, Wijmenga C, Sanna S. Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids. Nature Communications. 11: 4930. PMID 33004804 DOI: 10.1038/s41467-020-18716-x |
0.591 |
|
| 2020 |
Lu X, Fraszczyk E, van der Meer TP, van Faassen M, Bloks VW, Kema IP, van Beek AP, Li S, Franke L, Westra HJ, Xu X, Huo X, Snieder H, Wolffenbuttel BHR, et al. An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors. Environment International. 144: 106016. PMID 32916427 DOI: 10.1016/J.Envint.2020.106016 |
0.66 |
|
| 2020 |
de Vries DH, Matzaraki V, Bakker OB, Brugge H, Westra HJ, Netea MG, Franke L, Kumar V, van der Wijst MGP. Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response. Plos Pathogens. 16: e1008408. PMID 32251450 DOI: 10.1371/Journal.Ppat.1008408 |
0.659 |
|
| 2019 |
Amariuta T, Luo Y, Gazal S, Davenport EE, van de Geijn B, Ishigaki K, Westra HJ, Teslovich N, Okada Y, Yamamoto K, Price AL, Raychaudhuri S. IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors. American Journal of Human Genetics. PMID 31006511 DOI: 10.1016/J.Ajhg.2019.03.012 |
0.787 |
|
| 2018 |
van der Wijst MGP, de Vries DH, Brugge H, Westra HJ, Franke L. An integrative approach for building personalized gene regulatory networks for precision medicine. Genome Medicine. 10: 96. PMID 30567569 DOI: 10.1186/S13073-018-0608-4 |
0.684 |
|
| 2018 |
Davenport EE, Amariuta T, Gutierrez-Arcelus M, Slowikowski K, Westra HJ, Luo Y, Shen C, Rao DA, Zhang Y, Pearson S, von Schack D, Beebe JS, Bing N, John S, Vincent MS, et al. Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial. Genome Biology. 19: 168. PMID 30340504 DOI: 10.1186/S13059-018-1560-8 |
0.782 |
|
| 2018 |
Westra HJ, Martínez-Bonet M, Onengut-Gumuscu S, Lee A, Luo Y, Teslovich N, Worthington J, Martin J, Huizinga T, Klareskog L, Rantapaa-Dahlqvist S, Chen WM, Quinlan A, Todd JA, Eyre S, et al. Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. Nature Genetics. PMID 30224649 DOI: 10.1038/S41588-018-0216-7 |
0.594 |
|
| 2018 |
Li G, Martínez-Bonet M, Wu D, Yang Y, Cui J, Nguyen HN, Cunin P, Levescot A, Bai M, Westra HJ, Okada Y, Brenner MB, Raychaudhuri S, Hendrickson EA, Maas RL, et al. High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction. Nature Genetics. PMID 30013183 DOI: 10.1038/S41588-018-0159-Z |
0.579 |
|
| 2017 |
Kasela S, Kisand K, Tserel L, Kaleviste E, Remm A, Fischer K, Esko T, Westra HJ, Fairfax BP, Makino S, Knight JC, Franke L, Metspalu A, Peterson P, Milani L. Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells. Plos Genetics. 13: e1006643. PMID 28248954 DOI: 10.1371/Journal.Pgen.1006643 |
0.692 |
|
| 2016 |
Zhernakova DV, Deelen P, Vermaat M, van Iterson M, van Galen M, Arindrarto W, van 't Hof P, Mei H, van Dijk F, Westra HJ, Bonder MJ, van Rooij J, Verkerk M, Jhamai PM, Moed M, et al. Identification of context-dependent expression quantitative trait loci in whole blood. Nature Genetics. PMID 27918533 DOI: 10.1038/Ng.3737 |
0.837 |
|
| 2016 |
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Westra HJ, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 1591. PMID 27898078 DOI: 10.1038/Ng1216-1587B |
0.675 |
|
| 2016 |
van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I, Eijgelsheim M, Sotoodehnia N, Hayward C, Sorice R, Meirelles O, Lyytikäinen LP, Polašek O, ... ... Westra HJ, et al. 52 Genetic Loci Influencing Myocardial Mass. Journal of the American College of Cardiology. 68: 1435-48. PMID 27659466 DOI: 10.1016/J.Jacc.2016.07.729 |
0.757 |
|
| 2016 |
Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, ... ... Westra HJ, et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics. PMID 27618452 DOI: 10.1038/Ng.3667 |
0.697 |
|
| 2016 |
Okbay A, Baselmans BM, Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Westra HJ, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 970. PMID 27463399 DOI: 10.1038/ng0816-970c |
0.659 |
|
| 2016 |
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... Westra HJ, et al. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 12: e1006166. PMID 27355579 DOI: 10.1371/Journal.Pgen.1006166 |
0.71 |
|
| 2016 |
Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, ... ... Westra HJ, et al. Genome-wide association study identifies 74 loci associated with educational attainment. Nature. 533: 539-42. PMID 27225129 DOI: 10.1038/Nature17671 |
0.736 |
|
| 2016 |
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Westra HJ, et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. PMID 27089181 DOI: 10.1038/Ng.3552 |
0.7 |
|
| 2016 |
Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J, Han B, Park YR, Raychaudhuri S, Pouget JG, Hübenthal M, Folseraas T, Wang Y, Esko T, Metspalu A, Westra HJ, et al. Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nature Genetics. PMID 26974007 DOI: 10.1038/Ng.3528 |
0.737 |
|
| 2016 |
Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman ÅK, ... ... Westra HJ, et al. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications. 7: 10495. PMID 26833246 DOI: 10.1038/Ncomms10495 |
0.717 |
|
| 2015 |
Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T, Ramos YF, ... ... Westra HJ, et al. The transcriptional landscape of age in human peripheral blood. Nature Communications. 6: 8570. PMID 26490707 DOI: 10.1038/Ncomms9570 |
0.63 |
|
| 2015 |
Kogelman LJ, Zhernakova DV, Westra HJ, Cirera S, Fredholm M, Franke L, Kadarmideen HN. An integrative systems genetics approach reveals potential causal genes and pathways related to obesity. Genome Medicine. 7: 105. PMID 26482556 DOI: 10.1186/S13073-015-0229-0 |
0.715 |
|
| 2015 |
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... Westra HJ, et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 11: e1005378. PMID 26426971 DOI: 10.1371/Journal.Pgen.1005378 |
0.688 |
|
| 2015 |
Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, Abedian S, Cheon JH, Cho J, Daryani NE, Franke L, ... ... Westra HJ, et al. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nature Genetics. PMID 26192919 DOI: 10.1038/Ng.3359 |
0.742 |
|
| 2015 |
Trynka G, Westra HJ, Slowikowski K, Hu X, Xu H, Stranger BE, Klein RJ, Han B, Raychaudhuri S. Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci. American Journal of Human Genetics. 97: 139-52. PMID 26140449 DOI: 10.1016/J.Ajhg.2015.05.016 |
0.834 |
|
| 2015 |
Draisma HH, Pool R, Kobl M, Jansen R, Petersen AK, Vaarhorst AA, Yet I, Haller T, Demirkan A, Esko T, Zhu G, Böhringer S, Beekman M, van Klinken JB, Römisch-Margl W, ... ... Westra HJ, et al. Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature Communications. 6: 7208. PMID 26068415 DOI: 10.1038/Ncomms8208 |
0.722 |
|
| 2015 |
Surakka I, Horikoshi M, Mägi R, Sarin AP, Mahajan A, Lagou V, Marullo L, Ferreira T, Miraglio B, Timonen S, Kettunen J, Pirinen M, Karjalainen J, Thorleifsson G, Hägg S, ... ... Westra HJ, et al. The impact of low-frequency and rare variants on lipid levels. Nature Genetics. 47: 589-97. PMID 25961943 DOI: 10.1038/Ng.3300 |
0.716 |
|
| 2015 |
Westra HJ, Arends D, Esko T, Peters MJ, Schurmann C, Schramm K, Kettunen J, Yaghootkar H, Fairfax BP, Andiappan AK, Li Y, Fu J, Karjalainen J, Platteel M, Visschedijk M, et al. Cell Specific eQTL Analysis without Sorting Cells. Plos Genetics. 11: e1005223. PMID 25955312 DOI: 10.1371/Journal.Pgen.1005223 |
0.768 |
|
| 2015 |
Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der Meer P, Tanaka T, ... ... Westra HJ, et al. Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nature Communications. 6: 6542. PMID 25817829 DOI: 10.1038/Ncomms7542 |
0.626 |
|
| 2015 |
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, ... ... Westra HJ, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 518: 197-206. PMID 25673413 DOI: 10.1038/Nature14177 |
0.697 |
|
| 2015 |
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, ... ... Westra HJ, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 518: 187-96. PMID 25673412 DOI: 10.1038/Nature14132 |
0.726 |
|
| 2015 |
Jin P, Andiappan AK, Quek JM, Lee B, Au B, Sio YY, Irwanto A, Schurmann C, Grabe HJ, Suri BK, Matta SA, Westra HJ, Franke L, Esko T, Sun L, et al. A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis. The Journal of Allergy and Clinical Immunology. 135: 1486-1493.e8. PMID 25649076 DOI: 10.1016/J.Jaci.2014.12.1870 |
0.639 |
|
| 2015 |
Pers TH, Karjalainen JM, Chan Y, Westra HJ, Wood AR, Yang J, Lui JC, Vedantam S, Gustafsson S, Esko T, Frayling T, Speliotes EK, Boehnke M, Raychaudhuri S, et al. Biological interpretation of genome-wide association studies using predicted gene functions. Nature Communications. 6: 5890. PMID 25597830 DOI: 10.1038/Ncomms6890 |
0.764 |
|
| 2015 |
Fehrmann RS, Karjalainen JM, Krajewska M, Westra HJ, Maloney D, Simeonov A, Pers TH, Hirschhorn JN, Jansen RC, Schultes EA, van Haagen HH, de Vries EG, te Meerman GJ, Wijmenga C, van Vugt MA, et al. Gene expression analysis identifies global gene dosage sensitivity in cancer. Nature Genetics. 47: 115-25. PMID 25581432 DOI: 10.1038/Ng.3173 |
0.761 |
|
| 2015 |
Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, ... ... Westra HJ, et al. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry. 20: 647-56. PMID 25288136 DOI: 10.1038/Mp.2014.107 |
0.713 |
|
| 2015 |
Kumar V, Gutierrez-Achury J, Kanduri K, Almeida R, Hrdlickova B, Zhernakova DV, Westra HJ, Karjalainen J, Ricaño-Ponce I, Li Y, Stachurska A, Tigchelaar EF, Abdulahad WH, Lähdesmäki H, Hofker MH, et al. Systematic annotation of celiac disease loci refines pathological pathways and suggests a genetic explanation for increased interferon-gamma levels. Human Molecular Genetics. 24: 397-409. PMID 25190711 DOI: 10.1093/Hmg/Ddu453 |
0.77 |
|
| 2015 |
Andiappan AK, Narayanan S, Myers RA, Lee B, Nieuwenhuis MA, Nardin A, Park CS, Shin HD, Kim JH, Westra HJ, Franke L, Esko T, Metspalu A, Teo YY, Saw SM, et al. Genetic variants of inducible costimulator are associated with allergic asthma susceptibility. The Journal of Allergy and Clinical Immunology. 135: 556-8. PMID 25109803 DOI: 10.1016/J.Jaci.2014.06.028 |
0.64 |
|
| 2014 |
Deelen P, Bonder MJ, van der Velde KJ, Westra HJ, Winder E, Hendriksen D, Franke L, Swertz MA. Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration. Bmc Research Notes. 7: 901. PMID 25495213 DOI: 10.1186/1756-0500-7-901 |
0.781 |
|
| 2014 |
Pierce BL, Tong L, Chen LS, Rahaman R, Argos M, Jasmine F, Roy S, Paul-Brutus R, Westra HJ, Franke L, Esko T, Zaman R, Islam T, Rahman M, Baron JA, et al. Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians. Plos Genetics. 10: e1004818. PMID 25474530 DOI: 10.1371/Journal.Pgen.1004818 |
0.675 |
|
| 2014 |
Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der Meer P, Tanaka T, ... ... Westra HJ, et al. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nature Communications. 5: 4926. PMID 25352340 DOI: 10.1038/Ncomms5926 |
0.629 |
|
| 2014 |
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, ... ... Westra HJ, et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics. 46: 1173-86. PMID 25282103 DOI: 10.1038/Ng.3097 |
0.746 |
|
| 2014 |
Hemani G, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Yang J, Gibson G, Martin NG, Metspalu A, Franke L, Montgomery GW, Visscher PM, Powell JE. Hemani et al. reply. Nature. 514: E5-6. PMID 25279929 DOI: 10.1038/Nature13692 |
0.605 |
|
| 2014 |
Gockel I, Becker J, Wouters MM, Niebisch S, Gockel HR, Hess T, Ramonet D, Zimmermann J, Vigo AG, Trynka G, de León AR, de la Serna JP, Urcelay E, Kumar V, Franke L, ... Westra HJ, et al. Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. Nature Genetics. 46: 901-4. PMID 24997987 DOI: 10.1038/Ng.3029 |
0.79 |
|
| 2014 |
Cozen W, Timofeeva MN, Li D, Diepstra A, Hazelett D, Delahaye-Sourdeix M, Edlund CK, Franke L, Rostgaard K, Van Den Berg DJ, Cortessis VK, Smedby KE, Glaser SL, Westra HJ, Robison LL, et al. A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus. Nature Communications. 5: 3856. PMID 24920014 DOI: 10.1038/Ncomms4856 |
0.685 |
|
| 2014 |
Deelen P, Menelaou A, van Leeuwen EM, Kanterakis A, van Dijk F, Medina-Gomez C, Francioli LC, Hottenga JJ, Karssen LC, Estrada K, Kreiner-Møller E, Rivadeneira F, van Setten J, Gutierrez-Achury J, Westra HJ, et al. Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'. European Journal of Human Genetics : Ejhg. 22: 1321-6. PMID 24896149 DOI: 10.1038/Ejhg.2014.19 |
0.805 |
|
| 2014 |
Westra HJ, Franke L. From genome to function by studying eQTLs. Biochimica Et Biophysica Acta. 1842: 1896-1902. PMID 24798236 DOI: 10.1016/J.Bbadis.2014.04.024 |
0.769 |
|
| 2014 |
Li H, Chan L, Bartuzi P, Melton SD, Weber A, Ben-Shlomo S, Varol C, Raetz M, Mao X, Starokadomskyy P, van Sommeren S, Mokadem M, Schneider H, Weisberg R, Westra HJ, et al. Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer. Gastroenterology. 147: 184-195.e3. PMID 24727021 DOI: 10.1053/J.Gastro.2014.04.007 |
0.696 |
|
| 2014 |
Fransen K, van Sommeren S, Westra HJ, Veenstra M, Lamberts LE, Modderman R, Dijkstra G, Fu J, Wijmenga C, Franke L, Weersma RK, van Diemen CC. Correlation of genetic risk and messenger RNA expression in a Th17/IL23 pathway analysis in inflammatory bowel disease. Inflammatory Bowel Diseases. 20: 777-82. PMID 24662057 DOI: 10.1097/Mib.0000000000000013 |
0.729 |
|
| 2014 |
Hemani G, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Yang J, Gibson G, Martin NG, Metspalu A, Franke L, Montgomery GW, Visscher PM, Powell JE. Detection and replication of epistasis influencing transcription in humans. Nature. 508: 249-53. PMID 24572353 DOI: 10.1038/Nature13005 |
0.735 |
|
| 2014 |
Okada Y, Wu D, Trynka G, Raj T, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Yoshida S, Graham RR, Manoharan A, Ortmann W, Bhangale T, Denny JC, ... ... Westra HJ, et al. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 506: 376-81. PMID 24390342 DOI: 10.1038/Nature12873 |
0.813 |
|
| 2014 |
Almeida R, Ricaño-Ponce I, Kumar V, Deelen P, Szperl A, Trynka G, Gutierrez-Achury J, Kanterakis A, Westra HJ, Franke L, Swertz MA, Platteel M, Bilbao JR, Barisani D, Greco L, et al. Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant. Human Molecular Genetics. 23: 2481-9. PMID 24334606 DOI: 10.1093/Hmg/Ddt619 |
0.827 |
|
| 2013 |
Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE, Zhernakova A, Zhernakova DV, Veldink JH, Van den Berg LH, Karjalainen J, et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nature Genetics. 45: 1238-43. PMID 24013639 DOI: 10.1038/Ng.2756 |
0.762 |
|
| 2013 |
Zhernakova DV, de Klerk E, Westra HJ, Mastrokolias A, Amini S, Ariyurek Y, Jansen R, Penninx BW, Hottenga JJ, Willemsen G, de Geus EJ, Boomsma DI, Veldink JH, van den Berg LH, Wijmenga C, et al. DeepSAGE reveals genetic variants associated with alternative polyadenylation and expression of coding and non-coding transcripts. Plos Genetics. 9: e1003594. PMID 23818875 DOI: 10.1371/Journal.Pgen.1003594 |
0.792 |
|
| 2013 |
Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, et al. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (New York, N.Y.). 340: 1467-71. PMID 23722424 DOI: 10.1126/Science.1235488 |
0.691 |
|
| 2013 |
Trouw LA, Daha N, Kurreeman FA, Böhringer S, Goulielmos GN, Westra HJ, Zhernakova A, Franke L, Stahl EA, Levarht EW, Stoeken-Rijsbergen G, Verduijn W, Roos A, Li Y, Houwing-Duistermaat JJ, et al. Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis. Clinical and Experimental Immunology. 173: 76-83. PMID 23607884 DOI: 10.1111/Cei.12097 |
0.707 |
|
| 2013 |
den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, et al. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics. 45: 621-31. PMID 23583979 DOI: 10.1038/Ng.2610 |
0.741 |
|
| 2013 |
Cvejic A, Haer-Wigman L, Stephens JC, Kostadima M, Smethurst PA, Frontini M, van den Akker E, Bertone P, Bielczyk-Maczyńska E, Farrow S, Fehrmann RS, Gray A, de Haas M, Haver VG, Jordan G, ... ... Westra HJ, et al. SMIM1 underlies the Vel blood group and influences red blood cell traits. Nature Genetics. 45: 542-5. PMID 23563608 DOI: 10.1038/Ng.2603 |
0.684 |
|
| 2013 |
Knevel R, Krabben A, Wilson AG, Brouwer E, Leijsma MK, Lindqvist E, de Rooy DP, Daha NA, van der Linden MP, Tsonaka S, Zhernakova A, Westra HJ, Franke L, Houwing-Duistermaat JJ, Toes RE, et al. A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis. Arthritis and Rheumatism. 65: 582-9. PMID 23440692 DOI: 10.1002/Art.37808 |
0.62 |
|
| 2013 |
Kumar V, Westra HJ, Karjalainen J, Zhernakova DV, Esko T, Hrdlickova B, Almeida R, Zhernakova A, Reinmaa E, Võsa U, Hofker MH, Fehrmann RS, Fu J, Withoff S, Metspalu A, et al. Human disease-associated genetic variation impacts large intergenic non-coding RNA expression. Plos Genetics. 9: e1003201. PMID 23341781 DOI: 10.1371/Journal.Pgen.1003201 |
0.791 |
|
| 2013 |
Loos R, Hoed Md, Eijgelsheim M, Esko T, Peal DS, Segrè AV, Handsaker RE, Westra H, Johnson T, Yang J, Lundby A, Visscher PM, Willer C, Franke L, Sibon OC, et al. Identification of heart rate-associated loci and genes Protocol Exchange. DOI: 10.1038/Protex.2013.041 |
0.67 |
|
| 2012 |
van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan ST, Voss K, Weichenberger CX, Albers CA, ... ... Westra HJ, et al. Seventy-five genetic loci influencing the human red blood cell. Nature. 492: 369-75. PMID 23222517 DOI: 10.1038/Nature11677 |
0.697 |
|
| 2012 |
Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, ... ... Westra HJ, et al. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nature Genetics. 44: 1336-40. PMID 23143596 DOI: 10.1038/Ng.2462 |
0.829 |
|
| 2012 |
de Boer RA, Verweij N, van Veldhuisen DJ, Westra HJ, Bakker SJ, Gansevoort RT, Muller Kobold AC, van Gilst WH, Franke L, Mateo Leach I, van der Harst P. A genome-wide association study of circulating galectin-3. Plos One. 7: e47385. PMID 23056639 DOI: 10.1371/Journal.Pone.0047385 |
0.725 |
|
| 2012 |
Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, ... ... Westra HJ, et al. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. American Journal of Human Genetics. 91: 744-53. PMID 23022100 DOI: 10.1016/J.Ajhg.2012.08.021 |
0.691 |
|
| 2012 |
Fu J, Wolfs MG, Deelen P, Westra HJ, Fehrmann RS, Te Meerman GJ, Buurman WA, Rensen SS, Groen HJ, Weersma RK, van den Berg LH, Veldink J, Ophoff RA, Snieder H, van Heel D, et al. Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression. Plos Genetics. 8: e1002431. PMID 22275870 DOI: 10.1371/Journal.Pgen.1002431 |
0.826 |
|
| 2011 |
Johnson T, Gaunt TR, Newhouse SJ, Padmanabhan S, Tomaszewski M, Kumari M, Morris RW, Tzoulaki I, O'Brien ET, Poulter NR, Sever P, Shields DC, Thom S, Wannamethee SG, Whincup PH, ... ... Westra HJ, et al. Blood pressure loci identified with a gene-centric array. American Journal of Human Genetics. 89: 688-700. PMID 22100073 DOI: 10.1016/J.Ajhg.2011.10.013 |
0.734 |
|
| 2011 |
Sampietro ML, Trompet S, Verschuren JJ, Talens RP, Deelen J, Heijmans BT, de Winter RJ, Tio RA, Doevendans PA, Ganesh SK, Nabel EG, Westra HJ, Franke L, van den Akker EB, Westendorp RG, et al. A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention. Human Molecular Genetics. 20: 4748-57. PMID 21878436 DOI: 10.1093/Hmg/Ddr389 |
0.695 |
|
| 2011 |
Fehrmann RS, Jansen RC, Veldink JH, Westra HJ, Arends D, Bonder MJ, Fu J, Deelen P, Groen HJ, Smolonska A, Weersma RK, Hofstra RM, Buurman WA, Rensen S, Wolfs MG, et al. Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA. Plos Genetics. 7: e1002197. PMID 21829388 DOI: 10.1371/Journal.Pgen.1002197 |
0.839 |
|
| 2011 |
Westra HJ, Jansen RC, Fehrmann RS, te Meerman GJ, van Heel D, Wijmenga C, Franke L. MixupMapper: correcting sample mix-ups in genome-wide datasets increases power to detect small genetic effects. Bioinformatics (Oxford, England). 27: 2104-11. PMID 21653519 DOI: 10.1093/Bioinformatics/Btr323 |
0.73 |
|
| 2011 |
Szperl A, Ricaño-Ponce I, Li J, Deelen P, Kanterakis A, Plagnol V, van Dijk F, Westra H, Trynka G, Mulder C, Swertz M, Wijmenga C, Zheng HC. Exome sequencing in a family segregating for celiac disease Clinical Genetics. 80: 138-147. PMID 21627641 DOI: 10.1111/J.1399-0004.2011.01714.X |
0.799 |
|
| 2011 |
Hrdlickova B, Westra HJ, Franke L, Wijmenga C. Celiac disease: moving from genetic associations to causal variants. Clinical Genetics. 80: 203-313. PMID 21595655 DOI: 10.1111/j.1399-0004.2011.01707.x |
0.794 |
|
| 2011 |
Zhernakova A, Stahl EA, Trynka G, Raychaudhuri S, Festen EA, Franke L, Westra HJ, Fehrmann RS, Kurreeman FA, Thomson B, Gupta N, Romanos J, McManus R, Ryan AW, Turner G, et al. Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. Plos Genetics. 7: e1002004. PMID 21383967 DOI: 10.1371/Journal.Pgen.1002004 |
0.826 |
|
| 2011 |
Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, ... ... Westra HJ, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genetics. 43: 246-52. PMID 21297633 DOI: 10.1038/Ng.764 |
0.808 |
|
| 2011 |
Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, ... ... Westra H, et al. Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 Nature Genetics. 43: 919-919. DOI: 10.1038/Ng0911-919B |
0.76 |
|
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