| Year |
Citation |
Score |
| 2023 |
Schüssler M, Schott K, Fuchs NV, Oo A, Zahadi M, Rauch P, Kim B, König R. Gene editing of in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction, and cellular dNTP levels. Mbio. e0225223. PMID 37800914 DOI: 10.1128/mbio.02252-23 |
0.439 |
|
| 2023 |
Schüssler M, Schott K, Fuchs NV, Oo A, Zahadi M, Rauch P, Kim B, König R. Gene editing of in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction and cellular dNTP levels. Biorxiv : the Preprint Server For Biology. PMID 37662193 DOI: 10.1101/2023.08.24.554731 |
0.446 |
|
| 2023 |
Bowen NE, Tao S, Cho YJ, Schinazi RF, Kim B. Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages. The Journal of Biological Chemistry. 104984. PMID 37390988 DOI: 10.1016/j.jbc.2023.104984 |
0.407 |
|
| 2023 |
Singer MR, Dinh T, Levintov L, Annamalai AS, Rey JS, Briganti L, Cook NJ, Pye VE, Taylor IA, Kim K, Engelman AN, Kim B, Perilla JR, Kvaratskhelia M, Cherepanov P. The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. Mbio. e0356022. PMID 36744954 DOI: 10.1128/mbio.03560-22 |
0.358 |
|
| 2022 |
Bowen NE, Oo A, Kim B. Mechanistic Interplay between HIV-1 Reverse Transcriptase Enzyme Kinetics and Host SAMHD1 Protein: Viral Myeloid-Cell Tropism and Genomic Mutagenesis. Viruses. 14. PMID 35893688 DOI: 10.3390/v14081622 |
0.452 |
|
| 2021 |
Martinat C, Cormier A, Tobaly-Tapiero J, Palmic N, Casartelli N, Mahboubi B, Coggins SA, Buchrieser J, Persaud M, Diaz-Griffero F, Espert L, Bossis G, Lesage P, Schwartz O, Kim B, et al. SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells. Nature Communications. 12: 4582. PMID 34321470 DOI: 10.1038/s41467-021-24802-5 |
0.34 |
|
| 2021 |
Maehigashi T, Ahn S, Kim UI, Lindenberger J, Oo A, Koneru PC, Mahboubi B, Engelman AN, Kvaratskhelia M, Kim K, Kim B. A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site. Plos Pathogens. 17: e1009671. PMID 34293041 DOI: 10.1371/journal.ppat.1009671 |
0.351 |
|
| 2021 |
Roth M, McDaniel YZ, Daly MB, Talledge N, Greggs WM, Patterson SE, Kim B, Mansky LM. Distinct antiretroviral mechanisms elicited by a viral mutagen. Journal of Molecular Biology. 167111. PMID 34153286 DOI: 10.1016/j.jmb.2021.167111 |
0.396 |
|
| 2020 |
Coggins SA, Kim DH, Schinazi RF, Desrosier RC, Kim B. Enhanced enzyme kinetics of reverse transcriptase variants cloned from animals infected with SIVmac239 lacking viral protein X. The Journal of Biological Chemistry. 295: 16975-16986. PMID 33453952 DOI: 10.1074/jbc.RA120.015273 |
0.398 |
|
| 2020 |
Coggins SA, Kim DH, Schinazi RF, Desrosiers RC, Kim B. Enhanced enzyme kinetics of reverse transcriptase variants cloned from animals infected with SIVmac239 lacking Viral Protein X. The Journal of Biological Chemistry. PMID 33008888 DOI: 10.1074/jbc.RA120.015273 |
0.397 |
|
| 2020 |
Coggins SA, Mahboubi B, Schinazi RF, Kim B. Mechanistic Crosstalk between DNA/RNA Polymerase Enzyme Kinetics and Nucleotide Substrate Availability in Cells: Implications for Polymerase Inhibitor Discovery. The Journal of Biological Chemistry. PMID 32737197 DOI: 10.1074/Jbc.Rev120.013746 |
0.392 |
|
| 2020 |
Gandhi M, Groß M, Holler JM, Coggins SA, Patil N, Leupold JH, Munschauer M, Schenone M, Hartigan CR, Allgayer H, Kim B, Diederichs S. The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer. Nature Communications. 11: 3214. PMID 32587247 DOI: 10.1038/S41467-020-17007-9 |
0.31 |
|
| 2020 |
Benayas B, Sastre I, López-Martín S, Oo A, Kim B, Bullido MJ, Aldudo J, Yáñez-Mó M. Tetraspanin CD81 regulates HSV-1 infection. Medical Microbiology and Immunology. PMID 32500359 DOI: 10.1007/S00430-020-00684-0 |
0.367 |
|
| 2020 |
Balachander S, Gombolay AL, Yang T, Xu P, Newnam G, Keskin H, El-Sayed WMM, Bryksin AV, Tao S, Bowen NE, Schinazi RF, Kim B, Koh KD, Vannberg FO, Storici F. Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine. Nature Communications. 11: 2447. PMID 32415081 DOI: 10.1038/S41467-020-16152-5 |
0.338 |
|
| 2020 |
Coggins SA, Mahboubi B, Schinazi RF, Kim B. SAMHD1 Functions and Human Diseases. Viruses. 12. PMID 32244340 DOI: 10.3390/V12040382 |
0.412 |
|
| 2020 |
Poliaková M, Medo M, Koch J, Coggins S, Kim B, Aebersold DM, Zamboni N, Medová M, Zimmer Y. Abstract PR05: A metabolomics discovery profiling approach identifies an E2F1-associated purine synthesis pathway as a major component of the MET-DNA damage response network Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Pr05 |
0.344 |
|
| 2019 |
Qin Z, Bonifati S, St Gelais C, Li TW, Kim SH, Antonucci JM, Mahboubi B, Yount JS, Xiong Y, Kim B, Wu L. The dNTPase activity of SAMHD1 is important for its suppression of innate immune responses in differentiated monocytic cells. The Journal of Biological Chemistry. PMID 31914403 DOI: 10.1074/Jbc.Ra119.010360 |
0.34 |
|
| 2019 |
Basbous J, Aze A, Chaloin L, Lebdy R, Hodroj D, Ribeyre C, Larroque M, Shepard C, Kim B, Pruvost A, Moreaux J, Maiorano D, Mechali M, Constantinou A. Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites. Nucleic Acids Research. PMID 31853544 DOI: 10.1093/Nar/Gkz1162 |
0.368 |
|
| 2019 |
Oo A, Kim DH, Schinazi RF, Kim B. Viral protein X Reduces the Incorporation of Mutagenic Noncanonical rNTPs during Lentivirus Reverse Transcription in Macrophages. The Journal of Biological Chemistry. PMID 31806704 DOI: 10.1074/Jbc.Ra119.011466 |
0.515 |
|
| 2019 |
Shepard C, Xu J, Holler J, Kim DH, Mansky LM, Schinazi RF, Kim B. Effect of induced dNTP pool imbalance on HIV-1 reverse transcription in macrophages. Retrovirology. 16: 29. PMID 31655617 DOI: 10.1186/S12977-019-0491-0 |
0.469 |
|
| 2019 |
Coggins SA, Holler JM, Kimata JT, Kim DH, Schinazi RF, Kim B. Efficient pre-catalytic conformational change of reverse transcriptases from SAMHD1 non-counteracting primate lentiviruses during dNTP incorporation. Virology. 537: 36-44. PMID 31442614 DOI: 10.1016/J.Virol.2019.08.010 |
0.475 |
|
| 2019 |
Jung E, Nam S, Oh H, Jun S, Ro HJ, Kim B, Kim M, Go YY. Neutralization of Acidic Intracellular Vesicles by Niclosamide Inhibits Multiple Steps of the Dengue Virus Life Cycle In Vitro. Scientific Reports. 9: 8682. PMID 31213630 DOI: 10.1038/S41598-019-45095-1 |
0.346 |
|
| 2019 |
Buffone C, Kutzner J, Opp S, Martinez-Lopez A, Selyutina A, Coggings SA, Studdard LR, Ding L, Kim B, Spearman P, Schaller T, Diaz-Griffero F. The ability of SAMHD1 to block HIV-1 but not SIV requires expression of MxB. Virology. 531: 260-268. PMID 30959264 DOI: 10.1016/J.Virol.2019.03.018 |
0.485 |
|
| 2018 |
Plitnik T, Sharkey ME, Mahboubi B, Kim B, Stevenson M. Incomplete Suppression of HIV-1 by SAMHD1 Permits Efficient Macrophage Infection. Pathogens & Immunity. 3: 197-223. PMID 30656243 DOI: 10.20411/pai.v3i2.263 |
0.376 |
|
| 2018 |
Mahboubi B, Gavegnano C, Kim DH, Schinazi RF, Kim B. Host SAMHD1 protein restricts endogenous reverse transcription of HIV-1 in nondividing macrophages. Retrovirology. 15: 69. PMID 30316304 DOI: 10.1186/S12977-018-0452-Z |
0.527 |
|
| 2018 |
Gustafsson NMS, Färnegårdh K, Bonagas N, Ninou AH, Groth P, Wiita E, Jönsson M, Hallberg K, Lehto J, Pennisi R, Martinsson J, Norström C, Hollers J, Schultz J, Andersson M, ... ... Kim B, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nature Communications. 9: 3872. PMID 30250201 DOI: 10.2210/Pdb6Etj/Pdb |
0.362 |
|
| 2018 |
Mereby SA, Maehigashi T, Holler JM, Kim DH, Schinazi RF, Kim B. Interplay of ancestral non-primate lentiviruses with the virus-restricting SAMHD1 proteins of their hosts. The Journal of Biological Chemistry. PMID 30181218 DOI: 10.1074/Jbc.Ra118.004567 |
0.438 |
|
| 2018 |
Kueck T, Cassella E, Holler J, Kim B, Bieniasz PD. The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression. Elife. 7. PMID 30132758 DOI: 10.7554/Elife.38867 |
0.459 |
|
| 2018 |
Martinez-Lopez A, Martin-Fernandez M, Buta S, Kim B, Bogunovic D, Diaz-Griffero F. SAMHD1 deficient human monocytes autonomously trigger type I interferon. Molecular Immunology. 101: 450-460. PMID 30099227 DOI: 10.1016/J.Molimm.2018.08.005 |
0.331 |
|
| 2018 |
Osei Kuffour E, Schott K, Jaguva Vasudevan AA, Holler J, Schulz WA, Lang PA, Lang KS, Kim B, Häussinger D, König R, Münk C. USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1. Journal of Virology. PMID 30068654 DOI: 10.1128/Jvi.00592-18 |
0.498 |
|
| 2018 |
Wang Z, Bhattacharya A, White T, Buffone C, McCabe A, Nguyen LA, Shepard CN, Pardo S, Kim B, Weintraub ST, Demeler B, Diaz-Griffero F, Ivanov DN. Functionality of Redox-Active Cysteines Is Required for Restriction of Retroviral Replication by SAMHD1. Cell Reports. 24: 815-823. PMID 30044979 DOI: 10.1016/J.Celrep.2018.06.090 |
0.384 |
|
| 2018 |
Schott K, Fuchs NV, Derua R, Mahboubi B, Schnellbächer E, Seifried J, Tondera C, Schmitz H, Shepard C, Brandariz-Nuñez A, Diaz-Griffero F, Reuter A, Kim B, Janssens V, König R. Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit. Nature Communications. 9: 2227. PMID 29884836 DOI: 10.1038/S41467-018-04671-1 |
0.466 |
|
| 2018 |
Thientosapol ES, Bosnjak D, Durack T, Stevanovski I, van Geldermalsen M, Holst J, Jahan Z, Shepard C, Weninger W, Kim B, Brink R, Jolly CJ. SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29669924 DOI: 10.1073/Pnas.1719771115 |
0.329 |
|
| 2018 |
Herrmann A, Wittmann S, Thomas D, Shepard CN, Kim B, Ferreirós N, Gramberg T. The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation. Mobile Dna. 9: 11. PMID 29610582 DOI: 10.1186/S13100-018-0116-5 |
0.371 |
|
| 2018 |
St Gelais C, Kim SH, Maksimova VV, Buzovetsky O, Knecht K, Shepard C, Kim B, Xiong Y, Wu L. A Cyclin-binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation. Journal of Virology. PMID 29321329 DOI: 10.1128/Jvi.01787-17 |
0.509 |
|
| 2018 |
Oh C, Ryoo J, Park K, Kim B, Daly MB, Cho D, Ahn K. A central role for PI3K-AKT signaling pathway in linking SAMHD1-deficiency to the type I interferon signature. Scientific Reports. 8: 84. PMID 29311560 DOI: 10.1038/S41598-017-18308-8 |
0.303 |
|
| 2017 |
Valle-Casuso JC, Allouch A, David A, Lenzi GM, Studdard L, Barré-Sinoussi F, Müller-Trutwin M, Kim B, Pancino G, Sáez-Cirión A. p21 restricts HIV-1 in monocyte-derived dendritic cells through the reduction of dNTP biosynthesis and regulation of SAMHD1 antiviral activity. Journal of Virology. PMID 28931685 DOI: 10.1128/Jvi.01324-17 |
0.51 |
|
| 2017 |
Rocha-Perugini V, Suárez H, Álvarez S, López-Martín S, Lenzi GM, Vences-Catalán F, Levy S, Kim B, Muñoz-Fernández MA, Sánchez-Madrid F, Yáñez-Mó M. CD81 association with SAMHD1 enhances HIV-1 reverse transcription by increasing dNTP levels. Nature Microbiology. PMID 28871089 DOI: 10.1038/S41564-017-0019-0 |
0.449 |
|
| 2017 |
Daddacha W, Koyen AE, Bastien AJ, Head PE, Dhere VR, Nabeta GN, Connolly EC, Werner E, Madden MZ, Daly MB, Minten EV, Whelan DR, Schlafstein AJ, Zhang H, Anand R, ... ... Kim B, et al. SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination. Cell Reports. 20: 1921-1935. PMID 28834754 DOI: 10.1016/J.Celrep.2017.08.008 |
0.38 |
|
| 2017 |
Goetze RW, Kim DH, Schinazi RF, Kim B. A CRISPR/Cas9 approach reveals that the polymerase activity of DNA Polymerase β is dispensable for HIV-1 infection in dividing and nondividing cells. The Journal of Biological Chemistry. PMID 28684413 DOI: 10.1074/Jbc.M117.793661 |
0.728 |
|
| 2017 |
White TE, Brandariz-Nuñez A, Martinez-Lopez A, Knowlton C, Lenzi G, Kim B, Ivanov D, Diaz-Griffero F. A SAMHD1 mutation associated with Aicardi-Goutières Syndrome uncouples the ability of SAMHD1 to restrict HIV-1 from its ability to downmodulate type I interferon in humans. Human Mutation. PMID 28229507 DOI: 10.1002/Humu.23201 |
0.454 |
|
| 2017 |
Baldauf HM, Stegmann L, Schwarz SM, Ambiel I, Trotard M, Martin M, Burggraf M, Lenzi GM, Lejk H, Pan X, Fregoso OI, Lim ES, Abraham L, Nguyen LA, Rutsch F, ... ... Kim B, et al. Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28228523 DOI: 10.1073/Pnas.1613635114 |
0.485 |
|
| 2017 |
Mlcochova P, Sutherland KA, Watters SA, Bertoli C, de Bruin RA, Rehwinkel J, Neil SJ, Lenzi GM, Kim B, Khwaja A, Gage MC, Georgiou C, Chittka A, Yona S, Noursadeghi M, et al. A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages. The Embo Journal. PMID 28122869 DOI: 10.15252/Embj.201696025 |
0.399 |
|
| 2017 |
Hollenbaugh JA, Shelton J, Tao S, Amiralaei S, Liu P, Lu X, Goetze RW, Zhou L, Nettles JH, Schinazi RF, Kim B. Substrates and Inhibitors of SAMHD1. Plos One. 12: e0169052. PMID 28046007 DOI: 10.1371/Journal.Pone.0169052 |
0.689 |
|
| 2017 |
Valle-Casuso JC, Allouch A, David A, Lenzi G, Studdard L, Barré-Sinoussi F, Muller-Trutwin M, Kim B, Pancino G, Saez-Cirion A. p21 Restricts HIV-1 in Monocyte-Derived Dendritic Cells through the Reduction of Deoxynucleoside Triphosphate Biosynthesis and Regulation of SAMHD1 Antiviral Activity VIRUS-CELL INTERACTIONS crossm Journal of Neurovirology. 91: 1324-1341. DOI: 10.1128/Jvi |
0.513 |
|
| 2016 |
Bloch N, Gläsker S, Sitaram P, Hofmann H, Shepard CN, Schultz ML, Kim B, Landau NR. A Highly Active Isoform of Lentivirus Restriction Factor SAMHD1 in Mouse. The Journal of Biological Chemistry. PMID 27920203 DOI: 10.1074/Jbc.M116.743740 |
0.456 |
|
| 2016 |
Anacker DC, Aloor HL, Shepard CN, Lenzi GM, Johnson BA, Kim B, Moody CA. HPV31 utilizes the ATR-Chk1 pathway to maintain elevated RRM2 levels and a replication-competent environment in differentiating Keratinocytes. Virology. 499: 383-396. PMID 27764728 DOI: 10.1016/J.Virol.2016.09.028 |
0.349 |
|
| 2016 |
Antonucci JM, St Gelais C, de Silva S, Yount JS, Tang C, Ji X, Shepard C, Xiong Y, Kim B, Wu L. SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity. Nature Medicine. 22: 1072-1074. PMID 27711056 DOI: 10.1038/Nm.4163 |
0.487 |
|
| 2016 |
Bhattacharya A, Wang Z, White T, Buffone C, Nguyen LA, Shepard CN, Kim B, Demeler B, Diaz-Griffero F, Ivanov DN. Effects of T592 phosphomimetic mutations on tetramer stability and dNTPase activity of SAMHD1 can not explain the retroviral restriction defect. Scientific Reports. 6: 31353. PMID 27511536 DOI: 10.1038/Srep31353 |
0.389 |
|
| 2016 |
White TE, Brandariz-Nuñez A, Han K, Sawyer SL, Kim B, Diaz-Griffero F. Modulation of LINE-1 Retrotransposition by a Human SAMHD1 Polymorphism. Virology Reports. 6: 53-60. PMID 27482511 DOI: 10.1016/J.Virep.2016.06.001 |
0.346 |
|
| 2016 |
Juvekar A, Hu H, Yadegarynia S, Lyssiotis CA, Ullas S, Lien EC, Bellinger G, Son J, Hok RC, Seth P, Daly MB, Kim B, Scully R, Asara JM, Cantley LC, et al. Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion. Proceedings of the National Academy of Sciences of the United States of America. PMID 27402769 DOI: 10.1073/Pnas.1522223113 |
0.343 |
|
| 2016 |
Zerbato JM, Serrao E, Lenzi G, Kim B, Ambrose Z, Watkins SC, Engelman AN, Sluis-Cremer N. Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro. Journal of Virology. 90: 8059-73. PMID 27356901 DOI: 10.1128/Jvi.00553-16 |
0.469 |
|
| 2016 |
Sommer AF, Rivière L, Qu B, Schott K, Riess M, Ni Y, Shepard C, Schnellbächer E, Finkernagel M, Himmelsbach K, Welzel K, Kettern N, Donnerhak C, Münk C, Flory E, ... ... Kim B, et al. Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle. Scientific Reports. 6: 26616. PMID 27229711 DOI: 10.1038/Srep26616 |
0.362 |
|
| 2016 |
Bonifati S, Daly MB, St Gelais C, Kim SH, Hollenbaugh JA, Shepard C, Kennedy EM, Kim DH, Schinazi RF, Kim B, Wu L. SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells. Virology. 495: 92-100. PMID 27183329 DOI: 10.1016/J.Virol.2016.05.002 |
0.459 |
|
| 2016 |
Rawson JM, Roth ME, Xie J, Daly MB, Clouser CL, Landman SR, Reilly CS, Bonnac L, Kim B, Patterson SE, Mansky LM. Synergistic reduction of HIV-1 infectivity by 5-azacytidine and inhibitors of ribonucleotide reductase. Bioorganic & Medicinal Chemistry. PMID 27117260 DOI: 10.1016/J.Bmc.2016.03.052 |
0.458 |
|
| 2016 |
Daly MB, Roth ME, Bonnac L, Maldonado JO, Xie J, Clouser CL, Patterson SE, Kim B, Mansky LM. Dual anti-HIV mechanism of clofarabine. Retrovirology. 13: 20. PMID 27009333 DOI: 10.1186/S12977-016-0254-0 |
0.522 |
|
| 2016 |
Hollenbaugh JA, Montero C, Schinazi RF, Munger J, Kim B. Metabolic profiling during HIV-1 and HIV-2 infection of primary human monocyte-derived macrophages. Virology. 491: 106-114. PMID 26895248 DOI: 10.1016/J.Virol.2016.01.023 |
0.462 |
|
| 2016 |
Rawson JM, Daly MB, Xie J, Clouser CL, Landman SR, Reilly CS, Bonnac L, Kim B, Patterson SE, Mansky LM. 5-azacytidine enhances the mutagenesis of HIV-1 by reduction to 5-aza-2'-deoxycytidine. Antimicrobial Agents and Chemotherapy. PMID 26833151 DOI: 10.1128/Aac.03084-15 |
0.447 |
|
| 2016 |
Hollenbaugh JA, Kim B. HIV-1 Reverse Transcriptase-Based Assay to Determine Cellular dNTP Concentrations. Methods in Molecular Biology (Clifton, N.J.). 1354: 61-70. PMID 26714705 DOI: 10.1007/978-1-4939-3046-3_5 |
0.451 |
|
| 2015 |
Wang F, St Gelais C, de Silva S, Zhang H, Geng Y, Shepard C, Kim B, Yount JS, Wu L. Phosphorylation of mouse SAMHD1 regulates its restriction of human immunodeficiency virus type 1 infection, but not murine leukemia virus infection. Virology. 487: 273-284. PMID 26580513 DOI: 10.1016/J.Virol.2015.10.024 |
0.476 |
|
| 2015 |
Lenzi GM, Domaoal RA, Kim DH, Schinazi RF, Kim B. Mechanistic and Kinetic Differences Between Reverse Transcriptases of Vpx Coding and Non-coding Lentiviruses. The Journal of Biological Chemistry. PMID 26483545 DOI: 10.1074/Jbc.M115.691576 |
0.505 |
|
| 2015 |
Hollenbaugh JA, Schader SM, Schinazi RF, Kim B. Differential regulatory activities of viral protein X for anti-viral efficacy of nucleos(t)ide reverse transcriptase inhibitors in monocyte-derived macrophages and activated CD4(+) T cells. Virology. 485: 313-321. PMID 26319213 DOI: 10.1016/J.Virol.2015.08.006 |
0.446 |
|
| 2015 |
Li D, Schlaepfer E, Audigé A, Rochat MA, Ivic S, Knowlton CN, Kim B, Keppler OT, Speck RF. Vpx mediated degradation of SAMHD1 has only a very limited effect on lentiviral transduction rate in ex vivo cultured HSPCs. Stem Cell Research. 15: 271-280. PMID 26207584 DOI: 10.1016/J.Scr.2015.06.012 |
0.399 |
|
| 2015 |
Nguyen LA, Domaoal RA, Kennedy EM, Kim DH, Schinazi RF, Kim B. Pre-steady state kinetic analysis of HIV-1 reverse transcriptase for non-canonical ribonucleoside triphosphate incorporation and DNA synthesis from ribonucleoside-containing DNA template. Antiviral Research. 115: 75-82. PMID 25557601 DOI: 10.1016/J.Antiviral.2014.12.016 |
0.511 |
|
| 2015 |
Stevaert A, Nurra S, Pala N, Carcelli M, Rogolino D, Shepard C, Domaoal RA, Kim B, Alfonso-Prieto M, Marras SAE, Sechi M, Naesens L. An integrated biological approach to guide the development of metal-chelating inhibitors of influenza virus PA endonuclease Molecular Pharmacology. 87: 323-337. PMID 25477342 DOI: 10.1124/Mol.114.095588 |
0.341 |
|
| 2015 |
Kretschmer S, Wolf C, König N, Staroske W, Guck J, Häusler M, Luksch H, Nguyen LA, Kim B, Alexopoulou D, Dahl A, Rapp A, Cardoso MC, Shevchenko A, Lee-Kirsch MA. SAMHD1 prevents autoimmunity by maintaining genome stability. Annals of the Rheumatic Diseases. 74: e17. PMID 24445253 DOI: 10.1136/Annrheumdis-2013-204845 |
0.354 |
|
| 2014 |
Lenzi GM, Domaoal RA, Kim DH, Schinazi RF, Kim B. Kinetic variations between reverse transcriptases of viral protein X coding and noncoding lentiviruses. Retrovirology. 11: 111. PMID 25524560 DOI: 10.1186/S12977-014-0111-Y |
0.502 |
|
| 2014 |
Hollenbaugh JA, Tao S, Lenzi GM, Ryu S, Kim DH, Diaz-Griffero F, Schinazi RF, Kim B. dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages. Retrovirology. 11: 63. PMID 25158827 DOI: 10.1186/S12977-014-0063-2 |
0.439 |
|
| 2014 |
Beach LB, Rawson JM, Kim B, Patterson SE, Mansky LM. Novel inhibitors of human immunodeficiency virus type 2 infectivity. The Journal of General Virology. 95: 2778-83. PMID 25103850 DOI: 10.1099/Vir.0.069864-0 |
0.479 |
|
| 2014 |
Ryoo J, Choi J, Oh C, Kim S, Seo M, Kim SY, Seo D, Kim J, White TE, Brandariz-Nuñez A, Diaz-Griffero F, Yun CH, Hollenbaugh JA, Kim B, Baek D, et al. The ribonuclease activity of SAMHD1 is required for HIV-1 restriction. Nature Medicine. 20: 936-41. PMID 25038827 DOI: 10.1038/Nm.3626 |
0.508 |
|
| 2014 |
White TE, Brandariz-Nuñez A, Valle-Casuso JC, Knowlton C, Kim B, Sawyer SL, Diaz-Griffero F. Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility. Virology. 460: 34-44. PMID 25010268 DOI: 10.1016/J.Virol.2014.04.023 |
0.474 |
|
| 2014 |
Jeong JJ, Kim B, Kim DH. Ginsenoside Rb1 eliminates HIV-1 (D3)-transduced cytoprotective human macrophages by inhibiting the AKT pathway Journal of Medicinal Food. 17: 849-854. PMID 24983400 DOI: 10.1089/jmf.2013.3020 |
0.353 |
|
| 2014 |
Allouch A, David A, Amie SM, Lahouassa H, Chartier L, Margottin-Goguet F, Barré-Sinoussi F, Kim B, Sáez-Cirión A, Pancino G. Reply to Pauls et al.: P21 is a master regulator of HIV replication in macrophages through dNTP synthesis block Proceedings of the National Academy of Sciences of the United States of America. 111: E1325-E1326. PMID 24834497 DOI: 10.1073/Pnas.1322699111 |
0.385 |
|
| 2014 |
Zhang R, Bloch N, Nguyen LA, Kim B, Landau NR. SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells. Plos One. 9: e89558. PMID 24586870 DOI: 10.1371/Journal.Pone.0089558 |
0.509 |
|
| 2014 |
Reinhard C, Bottinelli D, Kim B, Luban J. Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration. Retrovirology. 11: 12. PMID 24485168 DOI: 10.1186/1742-4690-11-12 |
0.498 |
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| 2014 |
Nguyen LA, Kim DH, Daly MB, Allan KC, Kim B. Host SAMHD1 protein promotes HIV-1 recombination in macrophages. The Journal of Biological Chemistry. 289: 2489-96. PMID 24352659 DOI: 10.1074/Jbc.C113.522326 |
0.51 |
|
| 2014 |
Wulf GM, Juvekar A, Lyssiotis CA, Hu H, Yadegarynia S, Liu H, Kim B, Winter E, Scully R, Asara J, Cantley LC, Matulonis U. Abstract CT338: Combination of a PI3K- and a PARP-inhibitor to treat high-grade serous ovarian or triple-negative breast cancer Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Ct338 |
0.304 |
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| 2013 |
Brandariz-Nuñez A, Valle-Casuso JC, White TE, Nguyen L, Bhattacharya A, Wang Z, Demeler B, Amie S, Knowlton C, Kim B, Ivanov DN, Diaz-Griffero F. Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1. Retrovirology. 10: 131. PMID 24219908 DOI: 10.1186/1742-4690-10-131 |
0.474 |
|
| 2013 |
Van Cor-Hosmer SK, Kim DH, Daly MB, Daddacha W, Kim B. Restricted 5'-end gap repair of HIV-1 integration due to limited cellular dNTP concentrations in human primary macrophages. The Journal of Biological Chemistry. 288: 33253-62. PMID 24097986 DOI: 10.1074/Jbc.M113.486787 |
0.496 |
|
| 2013 |
Allouch A, David A, Amie SM, Lahouassa H, Chartier L, Margottin-Goguet F, Barré-Sinoussi F, Kim B, Sáez-Cirión A, Pancino G. P21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway Proceedings of the National Academy of Sciences of the United States of America. 110: E3997-E4006. PMID 24082141 DOI: 10.1073/Pnas.1306719110 |
0.506 |
|
| 2013 |
Behrendt R, Schumann T, Gerbaulet A, Nguyen LA, Schubert N, Alexopoulou D, Berka U, Lienenklaus S, Peschke K, Gibbert K, Wittmann S, Lindemann D, Weiss S, Dahl A, Naumann R, ... ... Kim B, et al. Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response. Cell Reports. 4: 689-96. PMID 23972988 DOI: 10.1016/J.Celrep.2013.07.037 |
0.359 |
|
| 2013 |
Amie SM, Bambara RA, Kim B. GTP is the primary activator of the anti-HIV restriction factor SAMHD1. The Journal of Biological Chemistry. 288: 25001-6. PMID 23880768 DOI: 10.1074/Jbc.C113.493619 |
0.453 |
|
| 2013 |
Jin Z, Smith LK, Rajwanshi VK, Kim B, Deval J. The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase. Plos One. 8: e68347. PMID 23874596 DOI: 10.1371/Journal.Pone.0068347 |
0.329 |
|
| 2013 |
Hollenbaugh JA, Gee P, Baker J, Daly MB, Amie SM, Tate J, Kasai N, Kanemura Y, Kim DH, Ward BM, Koyanagi Y, Kim B. Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells. Plos Pathogens. 9: e1003481. PMID 23825958 DOI: 10.1371/Journal.Ppat.1003481 |
0.45 |
|
| 2013 |
Jeong JJ, Kim B, Kim DH. Ginsenoside Rh1 eliminates the cytoprotective phenotype of human immunodeficiency virus type 1-transduced human macrophages by inhibiting the phosphorylation of pyruvate dehydrogenase lipoamide kinase isozyme 1 Biological and Pharmaceutical Bulletin. 36: 1088-1094. PMID 23811558 DOI: 10.1248/Bpb.B13-00013 |
0.442 |
|
| 2013 |
Amie SM, Daly MB, Noble E, Schinazi RF, Bambara RA, Kim B. Anti-HIV host factor SAMHD1 regulates viral sensitivity to nucleoside reverse transcriptase inhibitors via modulation of cellular deoxyribonucleoside triphosphate (dNTP) levels. The Journal of Biological Chemistry. 288: 20683-91. PMID 23744077 DOI: 10.1074/Jbc.M113.472159 |
0.528 |
|
| 2013 |
White TE, Brandariz-Nuñez A, Valle-Casuso JC, Amie S, Nguyen LA, Kim B, Tuzova M, Diaz-Griffero F. The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation. Cell Host & Microbe. 13: 441-51. PMID 23601106 DOI: 10.1016/J.Chom.2013.03.005 |
0.399 |
|
| 2013 |
Dragin L, Nguyen LA, Lahouassa H, Sourisce A, Kim B, Ramirez BC, Margottin-Goguet F. Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply. Retrovirology. 10: 30. PMID 23497353 DOI: 10.1186/1742-4690-10-30 |
0.489 |
|
| 2013 |
Gramberg T, Kahle T, Bloch N, Wittmann S, Müllers E, Daddacha W, Hofmann H, Kim B, Lindemann D, Landau NR. Restriction of diverse retroviruses by SAMHD1. Retrovirology. 10: 26. PMID 23497255 DOI: 10.1186/1742-4690-10-26 |
0.512 |
|
| 2013 |
Daddacha W, Noble E, Nguyen LA, Kennedy EM, Kim B. Effect of ribonucleotides embedded in a DNA template on HIV-1 reverse transcription kinetics and fidelity Journal of Biological Chemistry. 288: 12522-12532. PMID 23479739 DOI: 10.1074/Jbc.M113.458398 |
0.497 |
|
| 2013 |
Goujon C, Schaller T, Galão RP, Amie SM, Kim B, Olivieri K, Neil SJ, Malim MH. Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection. Retrovirology. 10: 23. PMID 23442224 DOI: 10.1186/1742-4690-10-23 |
0.494 |
|
| 2013 |
Amie SM, Noble E, Kim B. Intracellular nucleotide levels and the control of retroviral infections. Virology. 436: 247-54. PMID 23260109 DOI: 10.1016/J.Virol.2012.11.010 |
0.484 |
|
| 2013 |
White TE, Brandariz-Nuñez A, Valle-Casuso JC, Amie S, Nguyen L, Kim B, Brojatsch J, Diaz-Griffero F. Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1. Virology. 436: 81-90. PMID 23158101 DOI: 10.1016/J.Virol.2012.10.029 |
0.469 |
|
| 2013 |
Reinhard C, Botinelli D, Kim B, Luban J. Vpx rescue of HIV-1 from the antiviral state is independent of the intracellular nucleotide concentration Retrovirology. 10. DOI: 10.1186/1742-4690-10-S1-P71 |
0.504 |
|
| 2013 |
Dragin L, Nguyen L, Lahouassa H, Sourisce A, Kim B, Ramirez C, Margottin-Goguet F. Interferon-α blocks HIV-1 infection in non-dividing myeloid cells despite SAMHD1 degradation and high deoxynucleoside triphosphates supply Retrovirology. 10: 69. DOI: 10.1186/1742-4690-10-S1-P69 |
0.507 |
|
| 2013 |
Allouch A, David A, Amie S, Lahouassa H, Chartier L, Margottin-Goguet F, Barré-Sinoussi F, Kim B, Saez-Cirion A, Pancino G. RNR2 repression by p21 restricts reverse transcription of HIV-1 and related-lentiviruses in macrophages Retrovirology. 10. DOI: 10.1186/1742-4690-10-S1-O27 |
0.485 |
|
| 2013 |
Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, ... ... Kim B, et al. Erratum: Corrigendum: SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates Nature Immunology. 14: 877-877. DOI: 10.1038/Ni0813-877A |
0.366 |
|
| 2012 |
St Gelais C, de Silva S, Amie SM, Coleman CM, Hoy H, Hollenbaugh JA, Kim B, Wu L. SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons. Retrovirology. 9: 105. PMID 23231760 DOI: 10.1186/1742-4690-9-105 |
0.316 |
|
| 2012 |
Joh E, Hollenbaugh JA, Kim B, Kim D. Pleckstrin homology domain of Akt kinase: a proof of principle for highly specific and effective non-enzymatic anti-cancer target. Plos One. 7. PMID 23189201 DOI: 10.1371/Journal.Pone.0050424 |
0.301 |
|
| 2012 |
Perez JT, Zlatev I, Aggarwal S, Subramanian S, Sachidanandam R, Kim B, Manoharan M, tenOever BR. A small-RNA enhancer of viral polymerase activity. Journal of Virology. 86: 13475-85. PMID 23035211 DOI: 10.1128/Jvi.02295-12 |
0.334 |
|
| 2012 |
Hofmann H, Logue EC, Bloch N, Daddacha W, Polsky SB, Schultz ML, Kim B, Landau NR. The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus. Journal of Virology. 86: 12552-60. PMID 22973040 DOI: 10.1128/Jvi.01657-12 |
0.403 |
|
| 2012 |
Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burggraf M, Schenkova K, Ambiel I, Wabnitz G, Gramberg T, Panitz S, Flory E, Landau NR, Sertel S, Rutsch F, ... ... Kim B, et al. SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells. Nature Medicine. 18: 1682-7. PMID 22972397 DOI: 10.1038/Nm.2964 |
0.363 |
|
| 2012 |
Noble E, Cox A, Deval J, Kim B. Endonuclease substrate selectivity characterized with full-length PA of influenza A virus polymerase. Virology. 433: 27-34. PMID 22841552 DOI: 10.1016/J.Virol.2012.07.008 |
0.36 |
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| 2012 |
Gavegnano C, Kennedy EM, Kim B, Schinazi RF. The Impact of Macrophage Nucleotide Pools on HIV-1 Reverse Transcription, Viral Replication, and the Development of Novel Antiviral Agents. Molecular Biology International. 2012: 625983. PMID 22811909 DOI: 10.1155/2012/625983 |
0.532 |
|
| 2012 |
Capella C, Beltejar MJ, Brown C, Fong V, Daddacha W, Kim B, Dewhurst S. Selective modification of adenovirus replication can be achieved through rational mutagenesis of the adenovirus type 5 DNA polymerase. Journal of Virology. 86: 10484-93. PMID 22811532 DOI: 10.1128/Jvi.00739-12 |
0.454 |
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| 2012 |
Kim B, Nguyen LA, Daddacha W, Hollenbaugh JA. Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages. Journal of Biological Chemistry. 287: 21570-21574. PMID 22589553 DOI: 10.1074/Jbc.C112.374843 |
0.527 |
|
| 2012 |
Mock DJ, Hollenbaugh JA, Daddacha W, Overstreet MG, Lazarski CA, Fowell DJ, Kim B. Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection Plos Pathogens. 8. PMID 22496656 DOI: 10.1371/Journal.Ppat.1002635 |
0.496 |
|
| 2012 |
Kennedy EM, Amie SM, Bambara RA, Kim B. Frequent incorporation of ribonucleotides during HIV-1 reverse transcription and their attenuated repair in macrophages. The Journal of Biological Chemistry. 287: 14280-8. PMID 22383524 DOI: 10.1074/Jbc.M112.348482 |
0.532 |
|
| 2012 |
Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, ... ... Kim B, et al. SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates. Nature Immunology. 13: 223-8. PMID 22327569 DOI: 10.1038/Ni.2236 |
0.446 |
|
| 2012 |
Van Cor-Hosmer SK, Daddacha W, Kelly Z, Tsurumi A, Kennedy EM, Kim B. The impact of molecular manipulation in residue 114 of human immunodeficiency virus type-1 reverse transcriptase on dNTP substrate binding and viral replication Virology. 422: 393-401. PMID 22153297 DOI: 10.1016/J.Virol.2011.11.004 |
0.514 |
|
| 2012 |
Nguyen LA, Daddacha W, Rigby S, Bambara RA, Kim B. Altered strand transfer activity of a multiple-drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutant with a dipeptide fingers domain insertion. Journal of Molecular Biology. 415: 248-62. PMID 22100453 DOI: 10.1016/J.Jmb.2011.11.014 |
0.389 |
|
| 2011 |
Muchiri JM, Rigby ST, Nguyen LA, Kim B, Bambara RA. HIV-1 reverse transcriptase dissociates during strand transfer. Journal of Molecular Biology. 412: 354-64. PMID 21821047 DOI: 10.1016/J.Jmb.2011.07.055 |
0.447 |
|
| 2011 |
Aggarwal S, Dewhurst S, Takimoto T, Kim B. Biochemical impact of the host adaptation-associated PB2 E627K mutation on the temperature-dependent RNA synthesis kinetics of influenza A virus polymerase complex. The Journal of Biological Chemistry. 286: 34504-13. PMID 21816827 DOI: 10.1074/Jbc.M111.262048 |
0.35 |
|
| 2011 |
Kim Y, Hollenbaugh JA, Kim DH, Kim B. Novel PI3K/Akt inhibitors screened by the cytoprotective function of human immunodeficiency virus type 1 Tat. Plos One. 6: e21781. PMID 21765914 DOI: 10.1371/Journal.Pone.0021781 |
0.436 |
|
| 2011 |
Hollenbaugh JA, Munger J, Kim B. Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC-MS/MS analysis. Virology. 415: 153-9. PMID 21565377 DOI: 10.1016/J.Virol.2011.04.007 |
0.432 |
|
| 2011 |
Bussey KA, Desmet EA, Mattiacio JL, Hamilton A, Bradel-Tretheway B, Bussey HE, Kim B, Dewhurst S, Takimoto T. PA residues in the 2009 H1N1 pandemic influenza virus enhance avian influenza virus polymerase activity in mammalian cells. Journal of Virology. 85: 7020-8. PMID 21561908 DOI: 10.1128/Jvi.00522-11 |
0.351 |
|
| 2011 |
Noble E, Mathews DH, Chen JL, Turner DH, Takimoto T, Kim B. Biophysical analysis of influenza A virus RNA promoter at physiological temperatures. The Journal of Biological Chemistry. 286: 22965-70. PMID 21555520 DOI: 10.1074/Jbc.M111.239509 |
0.313 |
|
| 2011 |
Kennedy EM, Daddacha W, Slater R, Gavegnano C, Fromentin E, Schinazi RF, Kim B. Abundant non-canonical dUTP found in primary human macrophages drives its frequent incorporation by HIV-1 reverse transcriptase Journal of Biological Chemistry. 286: 25047-25055. PMID 21454906 DOI: 10.1074/Jbc.M111.234047 |
0.513 |
|
| 2010 |
Lucas A, Kim Y, Rivera-Pabon O, Chae S, Kim DH, Kim B. Targeting the PI3K/Akt cell survival pathway to induce cell death of HIV-1 infected macrophages with alkylphospholipid compounds. Plos One. 5. PMID 20927348 DOI: 10.1371/Journal.Pone.0013121 |
0.489 |
|
| 2010 |
Kennedy EM, Gavegnano C, Nguyen L, Slater R, Lucas A, Fromentin E, Schinazi RF, Kim B. Ribonucleoside triphosphates as substrate of human immunodeficiency virus type 1 reverse transcriptase in human macrophages Journal of Biological Chemistry. 285: 39380-39391. PMID 20924117 DOI: 10.1074/Jbc.M110.178582 |
0.533 |
|
| 2010 |
Cor-Hosmer SKV, Daddacha W, Kim B. Mechanistic interplay among the M184I HIV-1 reverse transcriptase mutant, the central polypurine tract, cellular dNTP concentrations and drug sensitivity. Virology. 406: 253-260. PMID 20701944 DOI: 10.1016/J.Virol.2010.07.028 |
0.413 |
|
| 2010 |
Aggarwal S, Bradel-Tretheway B, Takimoto T, Dewhurst S, Kim B. Biochemical characterization of enzyme fidelity of influenza A virus RNA polymerase complex. Plos One. 5: e10372. PMID 20454455 DOI: 10.1371/Journal.Pone.0010372 |
0.405 |
|
| 2010 |
Bussey KA, Bousse TL, Desmet EA, Kim B, Takimoto T. PB2 residue 271 plays a key role in enhanced polymerase activity of influenza A viruses in mammalian host cells. Journal of Virology. 84: 4395-406. PMID 20181719 DOI: 10.1128/Jvi.02642-09 |
0.362 |
|
| 2009 |
Kennedy EM, Hergott C, Dewhurst S, Kim B. The mechanistic architecture of thermostable Pyrococcus furiosus family B DNA polymerase motif A and its interaction with the dNTP substrate. Biochemistry. 48: 11161-8. PMID 19817489 DOI: 10.1021/Bi9010122 |
0.362 |
|
| 2009 |
Bimber BN, Chugh P, Giorgi EE, Kim B, Almudevar AL, Dewhurst S, O'Connor DH, Lee HY. Nef gene evolution from a single transmitted strain in acute SIV infection. Retrovirology. 6: 57. PMID 19505314 DOI: 10.1186/1742-4690-6-57 |
0.377 |
|
| 2009 |
Skasko M, Diamond TL, Kim B. Mechanistic variations among reverse transcriptases of simian immunodeficiency virus variants isolated from African green monkeys. Biochemistry. 48: 5389-5395. PMID 19408961 DOI: 10.1021/Bi900346M |
0.41 |
|
| 2008 |
Bradel-Tretheway BG, Kelley Z, Chakraborty-Sett S, Takimoto T, Kim B, Dewhurst S. The human H5N1 influenza A virus polymerase complex is active in vitro over a broad range of temperatures, in contrast to the WSN complex, and this property can be attributed to the PB2 subunit. The Journal of General Virology. 89: 2923-32. PMID 19008377 DOI: 10.1099/Vir.0.2008/006254-0 |
0.312 |
|
| 2008 |
Santos-Velazquez J, Kim B. Deoxynucleoside Triphosphate Incorporation Mechanism of Foamy Virus (FV) Reverse Transcriptase: Implications for Cell Tropism of FV Journal of Virology. 82: 8235-8238. PMID 18508890 DOI: 10.1128/Jvi.00088-08 |
0.489 |
|
| 2008 |
Skasko M, Kim B. Compensatory Role of Human Immunodeficiency Virus Central Polypurine Tract Sequence in Kinetically Disrupted Reverse Transcription Journal of Virology. 82: 7716-7720. PMID 18495776 DOI: 10.1128/Jvi.00120-08 |
0.506 |
|
| 2008 |
Chugh P, Bradel-Tretheway B, Monteiro-Filho CM, Planelles V, Maggirwar SB, Dewhurst S, Kim B. Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy. Retrovirology. 5: 11. PMID 18237430 DOI: 10.1186/1742-4690-5-11 |
0.484 |
|
| 2008 |
Gao L, Hanson MN, Balakrishnan M, Boyer PL, Roques BP, Hughes SH, Kim B, Bambara RA. Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect. The Journal of Biological Chemistry. 283: 9196-205. PMID 18218634 DOI: 10.1074/Jbc.M710148200 |
0.439 |
|
| 2008 |
Jamburuthugoda VK, Santos-Velazquez JM, Skasko M, Operario DJ, Purohit V, Chugh P, Szymanski EA, Wedekind JE, Bambara RA, Kim B. Reduced dNTP binding affinity of 3TC-resistant M184I HIV-1 reverse transcriptase variants responsible for viral infection failure in macrophage. The Journal of Biological Chemistry. 283: 9206-16. PMID 18218633 DOI: 10.1074/Jbc.M710149200 |
0.494 |
|
| 2008 |
Matamoros T, Kim B, Menéndez-Arias L. Mechanistic insights into the role of Val75 of HIV-1 reverse transcriptase in misinsertion and mispair extension fidelity of DNA synthesis. Journal of Molecular Biology. 375: 1234-1248. PMID 18155043 DOI: 10.1016/J.Jmb.2007.11.021 |
0.411 |
|
| 2007 |
Purohit V, Roques BP, Kim B, Bambara RA. Mechanisms that prevent template inactivation by HIV-1 reverse transcriptase RNase H cleavages. The Journal of Biological Chemistry. 282: 12598-609. PMID 17337733 DOI: 10.1074/Jbc.M700043200 |
0.45 |
|
| 2007 |
Chugh P, Fan S, Planelles V, Maggirwar SB, Dewhurst S, Kim B. Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line. Journal of Molecular Biology. 366: 67-81. PMID 17157319 DOI: 10.1016/J.Jmb.2006.11.011 |
0.503 |
|
| 2006 |
Operario DJ, Balakrishnan M, Bambara RA, Kim B. Reduced dNTP interaction of human immunodeficiency virus type 1 reverse transcriptase promotes strand transfer. The Journal of Biological Chemistry. 281: 32113-21. PMID 16926150 DOI: 10.1074/Jbc.M604665200 |
0.472 |
|
| 2006 |
Jamburuthugoda VK, Chugh P, Kim B. Modification of human immunodeficiency virus type 1 reverse transcriptase to target cells with elevated cellular dNTP concentrations. Journal of Biological Chemistry. 281: 13388-13395. PMID 16497663 DOI: 10.1074/Jbc.M600291200 |
0.471 |
|
| 2006 |
Mock DJ, Chugh P, Kim B, Pröschel C, Dietrich J, Strathmann F, Blumberg BM, Mayer-Pröschel M. Characterization of specific HHV-6 and cell cycle genes implicated in virus-mediated G1/S cell-cycle arrest of glial precursors Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S65 |
0.38 |
|
| 2005 |
Purohit V, Balakrishnan M, Kim B, Bambara RA. Evidence that HIV-1 reverse transcriptase employs the DNA 3' end-directed primary/secondary RNase H cleavage mechanism during synthesis and strand transfer. The Journal of Biological Chemistry. 280: 40534-43. PMID 16221683 DOI: 10.1074/Jbc.M507839200 |
0.396 |
|
| 2005 |
Jamburuthugoda VK, Guo D, Wedekind JE, Kim B. Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate. Biochemistry. 44: 10635-43. PMID 16060672 DOI: 10.1021/Bi050611+ |
0.43 |
|
| 2005 |
Operario DJ, Reynolds HM, Kim B. Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. Virology. 335: 106-121. PMID 15823610 DOI: 10.1016/J.Virol.2005.02.010 |
0.442 |
|
| 2005 |
Dehart JL, Andersen JL, Zimmerman ES, Ardon O, An DS, Blackett J, Kim B, Planelles V. The ataxia telangiectasia-mutated and Rad3-related protein is dispensable for retroviral integration. Journal of Virology. 79: 1389-96. PMID 15650165 DOI: 10.1128/Jvi.79.3.1389-1396.2005 |
0.384 |
|
| 2005 |
Skasko M, Weiss KK, Reynolds HM, Jamburuthugoda V, Lee K, Kim B. Mechanistic Differences in RNA-dependent DNA Polymerization and Fidelity between Murine Leukemia Virus and HIV-1 Reverse Transcriptases Journal of Biological Chemistry. 280: 12190-12200. PMID 15644314 DOI: 10.1074/Jbc.M412859200 |
0.513 |
|
| 2004 |
Diamond TL, Roshal M, Jamburuthugoda VK, Reynolds HM, Merriam AR, Lee KY, Balakrishnan M, Bambara RA, Planelles V, Dewhurst S, Kim B. Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase. The Journal of Biological Chemistry. 279: 51545-53. PMID 15452123 DOI: 10.1074/Jbc.M408573200 |
0.537 |
|
| 2004 |
Weiss KK, Chen R, Skasko M, Reynolds HM, Lee K, Bambara RA, Mansky LM, Kim B. A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis. Biochemistry. 43: 4490-500. PMID 15078095 DOI: 10.1021/Bi035258R |
0.433 |
|
| 2003 |
Diamond TL, Souroullas G, Weiss KK, Lee KY, Bambara RA, Dewhurst S, Kim B. Mechanistic understanding of an altered fidelity simian immunodeficiency virus reverse transcriptase mutation, V148I, identified in a pig-tailed macaque Journal of Biological Chemistry. 278: 29913-29924. PMID 12740369 DOI: 10.1074/Jbc.M211754200 |
0.346 |
|
| 2003 |
Roshal M, Kim B, Zhu Y, Nghiem P, Planelles V. Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R. The Journal of Biological Chemistry. 278: 25879-86. PMID 12738771 DOI: 10.1074/Jbc.M303948200 |
0.517 |
|
| 2002 |
Weiss KK, Bambara RA, Kim B. Mechanistic role of residue Gln151 in error prone DNA synthesis by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Pre-steady state kinetic study of the Q151N HIV-1 RT mutant with increased fidelity. The Journal of Biological Chemistry. 277: 22662-9. PMID 11927582 DOI: 10.1074/Jbc.M200202200 |
0.477 |
|
| 2001 |
Malboeuf CM, Isaacs SJ, Tran NH, Kim B. Thermal effects on reverse transcription: improvement of accuracy and processivity in cDNA synthesis. Biotechniques. 30: 1074-1084. PMID 11355343 DOI: 10.2144/01305Rr06 |
0.341 |
|
| 2000 |
Weiss KK, Isaacs SJ, Tran NH, Adman ET, Kim B. Molecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions. Biochemistry. 39: 10684-10694. PMID 10978152 DOI: 10.1021/Bi000788Y |
0.46 |
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