| Year |
Citation |
Score |
| 2024 |
Chesler L, Schlieve C, Goldenberg DD, Kenney A, Kim G, McMillan A, Matthay KK, Rowitch D, Weiss WA. Editor's Note: Inhibition of Phosphatidylinositol 3-Kinase Destabilizes Mycn Protein and Blocks Malignant Progression in Neuroblastoma. Cancer Research. 84: 3311. PMID 39350668 DOI: 10.1158/0008-5472.CAN-24-2888 |
0.576 |
|
| 2024 |
Kumar P, Koach J, Nekritz E, Mukherjee S, Braun BS, DuBois SG, Nasholm N, Haas-Kogan D, Matthay KK, Weiss WA, Gustafson C, Seo Y. Aurora Kinase A inhibition enhances DNA damage and tumor cell death with I-MIBG therapy in high-risk neuroblastoma. Ejnmmi Research. 14: 54. PMID 38869684 DOI: 10.1186/s13550-024-01112-7 |
0.81 |
|
| 2024 |
Huang M, Fang W, Farrel A, Li L, Chronopoulos A, Nasholm N, Cheng B, Zheng T, Yoda H, Barata MJ, Porras T, Miller ML, Zhen Q, Ghiglieri L, McHenry L, ... ... Weiss WA, et al. ALK upregulates POSTN and WNT signaling to drive neuroblastoma. Cell Reports. 43: 113927. PMID 38451815 DOI: 10.1016/j.celrep.2024.113927 |
0.835 |
|
| 2024 |
Kumar P, Koach J, Nekritz E, Mukherjee S, Braun BS, DuBois SG, Nasholm N, Haas-Kogan D, Matthay KK, Weiss WA, Gustafson C, Seo Y. Aurora Kinase A inhibition enhances DNA damage and tumor cell death with 131I-MIBG therapy in high-risk neuroblastoma. Research Square. PMID 38313265 DOI: 10.21203/rs.3.rs-3845114/v1 |
0.815 |
|
| 2023 |
Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, ... ... Weiss WA, et al. The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. Nature Communications. 14: 6173. PMID 37798301 DOI: 10.1038/s41467-023-41836-z |
0.433 |
|
| 2023 |
Luo Z, Xin D, Liao Y, Berry K, Ogurek S, Zhang F, Zhang L, Zhao C, Rao R, Dong X, Li H, Yu J, Lin Y, Huang G, Xu L, ... ... Weiss WA, et al. Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability. Nature Communications. 14: 762. PMID 36765089 DOI: 10.1038/s41467-023-36400-8 |
0.346 |
|
| 2022 |
Kuzuoglu-Ozturk D, Aksoy O, Schmidt C, Lea R, Larson JD, Phelps RRL, Nasholm N, Holt M, Contreras A, Huang M, Wong-Michalak S, Shao H, Wechsler-Reya R, Phillips JJ, Gestwicki JE, ... ... Weiss WA, et al. N-myc mediated translation control is a therapeutic vulnerability in medulloblastoma. Cancer Research. PMID 36264168 DOI: 10.1158/0008-5472.CAN-22-0945 |
0.746 |
|
| 2022 |
Vaishnavi A, Juan J, Jacob M, Stehn C, Gardner EE, Scherzer MT, Schuman S, van Veen JE, Murphy B, Hackett CS, Dupuy AJ, Chmura SA, van der Weyden L, Newberg JY, Liu A, ... ... Weiss WA, et al. Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis. Cancer Research. PMID 36112789 DOI: 10.1158/0008-5472.CAN-21-3214 |
0.737 |
|
| 2022 |
Zhang Z, Fan Q, Luo X, Lou K, Weiss WA, Shokat KM. Brain-restricted mTOR inhibition with binary pharmacology. Nature. 609: 822-828. PMID 36104566 DOI: 10.1038/s41586-022-05213-y |
0.477 |
|
| 2022 |
Becklin KL, Draper GM, Madden RA, Kluesner MG, Koga T, Huang M, Weiss WA, Spector LG, Largaespada DA, Moriarity BS, Webber BR. Developing Bottom-Up Induced Pluripotent Stem Cell Derived Solid Tumor Models Using Precision Genome Editing Technologies. The Crispr Journal. 5: 517-535. PMID 35972367 DOI: 10.1089/crispr.2022.0032 |
0.74 |
|
| 2022 |
du Chatinier A, Meel MH, Das AI, Metselaar DS, Waranecki P, Bugiani M, Breur M, Simonds EF, Lu ED, Weiss WA, Garcia Vallejo JJ, Hoving EW, Phoenix TN, Hulleman E. Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma. Neuro-Oncology Advances. 4: vdac079. PMID 35733514 DOI: 10.1093/noajnl/vdac079 |
0.694 |
|
| 2021 |
Yi JS, Sias-Garcia O, Nasholm N, Hu X, Iniguez AB, Hall MD, Davis M, Guha R, Moreno-Smith M, Barbieri E, Duong K, Koach J, Qi J, Bradner JE, Stegmaier K, ... Weiss WA, et al. The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP53. Neoplasia (New York, N.Y.). 23: 624-633. PMID 34107377 DOI: 10.1016/j.neo.2021.05.003 |
0.723 |
|
| 2021 |
Simonds EF, Lu ED, Badillo O, Karimi S, Liu EV, Tamaki W, Rancan C, Downey KM, Stultz J, Sinha M, McHenry LK, Nasholm NM, Chuntova P, Sundström A, Genoud V, ... ... Weiss WA, et al. Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma. Journal For Immunotherapy of Cancer. 9. PMID 34083417 DOI: 10.1136/jitc-2020-002181 |
0.754 |
|
| 2021 |
Skowron P, Farooq H, Cavalli FMG, Morrissy AS, Ly M, Hendrikse LD, Wang EY, Djambazian H, Zhu H, Mungall KL, Trinh QM, Zheng T, Dai S, Stucklin ASG, Vladoiu MC, ... ... Weiss WA, et al. The transcriptional landscape of Shh medulloblastoma. Nature Communications. 12: 1749. PMID 33741928 DOI: 10.1038/s41467-021-21883-0 |
0.303 |
|
| 2021 |
Wolpaw AJ, Bayliss R, Büchel G, Dang CV, Eilers M, Gustafson WC, Hansen GM, Jura N, Knapp S, Lemmon MA, Levens D, Maris JM, Marmorstein R, Metallo SJ, Park JR, ... ... Weiss WA, et al. Drugging the 'undruggable' MYCN oncogenic transcription factor: Overcoming previous obstacles to impact childhood cancers. Cancer Research. PMID 33509943 DOI: 10.1158/0008-5472.CAN-20-3108 |
0.78 |
|
| 2020 |
Luo X, Weiss WA. Utility of Human-Derived Models for Glioblastoma. Cancer Discovery. 10: 907-909. PMID 32611734 DOI: 10.1158/2159-8290.Cd-20-0493 |
0.384 |
|
| 2020 |
von Achenbach C, Silginer M, Blot V, Weiss WA, Weller M. Depatuxizumab mafodotin (ABT-414)-induced glioblastoma cell death requires EGFR overexpression, but not EGFRY1068 phosphorylation. Molecular Cancer Therapeutics. PMID 32371586 DOI: 10.1158/1535-7163.Mct-19-0609 |
0.415 |
|
| 2019 |
Wong RA, Luo X, Lu M, An Z, Haas-Kogan DA, Philips JJ, Shokat KM, Weiss WA, Fan QW. Cooperative blockade of PKCα and JAK2 drives apoptosis in glioblastoma. Cancer Research. PMID 31806641 DOI: 10.1158/0008-5472.Can-18-2808 |
0.598 |
|
| 2019 |
Fan Q, An Z, Wong RA, Luo X, Lu E, Baldwin A, Mayekar MK, Haderk F, Shokat KM, Bivona TG, Weiss WA. Betacellulin drives therapy-resistance in glioblastoma. Neuro-Oncology. PMID 31678994 DOI: 10.1093/Neuonc/Noz206 |
0.523 |
|
| 2019 |
Qadeer ZA, Valle-Garcia D, Hasson D, Sun Z, Cook A, Nguyen C, Soriano A, Ma A, Griffiths LM, Zeineldin M, Filipescu D, Jubierre L, Chowdhury A, Deevy O, Chen X, ... ... Weiss WA, et al. ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures. Cancer Cell. PMID 31631027 DOI: 10.1016/J.Ccell.2019.09.002 |
0.34 |
|
| 2019 |
Zhang L, He X, Liu X, Zhang F, Huang LF, Potter AS, Xu L, Zhou W, Zheng T, Luo Z, Berry KP, Pribnow A, Smith SM, Fuller C, Jones BV, ... ... Weiss WA, et al. Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse. Cancer Cell. PMID 31474569 DOI: 10.1016/J.Ccell.2019.07.009 |
0.755 |
|
| 2019 |
Chatterjee N, Pazarentzos E, Mayekar MK, Gui P, Allegakoen DV, Hrustanovic G, Olivas V, Lin L, Verschueren E, Johnson JR, Hofree M, Yan JJ, Newton BW, Dollen JV, Earnshaw CH, ... ... Weiss WA, et al. Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers. Cell Reports. 28: 2317-2330.e8. PMID 31461649 DOI: 10.1016/J.Celrep.2019.07.063 |
0.423 |
|
| 2019 |
Sabelström H, Petri R, Shchors K, Jandial R, Schmidt C, Sacheva R, Masic S, Yuan E, Fenster T, Martinez M, Saxena S, Nicolaides TP, Ilkhanizadeh S, Berger MS, Snyder EY, ... Weiss WA, et al. Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness. Cell Reports. 28: 2064-2079.e11. PMID 31433983 DOI: 10.1016/J.Celrep.2019.07.071 |
0.796 |
|
| 2019 |
An Z, Weiss WA. In Vitro Assay to Study Tumor-macrophage Interaction. Journal of Visualized Experiments : Jove. PMID 31424440 DOI: 10.3791/59907 |
0.432 |
|
| 2019 |
McKinney A, Lindberg OR, Engler JR, Chen KY, Kumar A, Gong H, Lu KV, Simonds EF, Cloughesy TF, Liau LM, Prados M, Bollen AW, Berger MS, Shieh JTC, James CD, ... ... Weiss WA, et al. Mechanisms of resistance to EGFR inhibition reveal metabolic vulnerabilities in human GBM. Molecular Cancer Therapeutics. PMID 31270152 DOI: 10.1158/1535-7163.Mct-18-1330 |
0.813 |
|
| 2019 |
Huang M, Tailor J, Zhen Q, Gillmor AH, Miller ML, Weishaupt H, Chen J, Zheng T, Nash EK, McHenry LK, An Z, Ye F, Takashima Y, Clarke J, Ayetey H, ... ... Weiss WA, et al. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. Cell Stem Cell. PMID 31204176 DOI: 10.1016/J.Stem.2019.05.013 |
0.807 |
|
| 2019 |
Lee C, Rudneva VA, Erkek S, Zapatka M, Chau LQ, Tacheva-Grigorova SK, Garancher A, Rusert JM, Aksoy O, Lea R, Mohammad HP, Wang J, Weiss WA, Grimes HL, Pfister SM, et al. Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma. Nature Communications. 10: 332. PMID 30659187 DOI: 10.1038/S41467-018-08269-5 |
0.451 |
|
| 2019 |
Tailor J, Huang M, Smith A, Weiss WA. Recapitulation of Genetic Predisposition to Medulloblastoma in Human Neuroepithelial Stem Cells Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_216 |
0.764 |
|
| 2019 |
Wen Fan Q, Lorenzana E, Luo X, Lea R, Aksoy O, An Z, Ozawa T, Wassarman D, Shokat K, Aggen J, Smith JAM, Singh M, Butowski N, Raleigh D, Weiss W. DDIS-33. SELECTIVE AND COMPLETE INHIBITION OF mTORC1 BY BI-STERIC mTOR INHIBITORS DRIVES THERAPEUTIC RESPONSE IN GLIOBLASTOMA Neuro-Oncology. 21: vi70-vi70. DOI: 10.1093/Neuonc/Noz175.284 |
0.61 |
|
| 2019 |
Achenbach Cv, Blot V, Weiss W, Weller M. Csig-06. Depatuxizumab Mafodotin (Abt-414)-Induced Glioblastoma Cell Death Requires Egfr Overexpression, But Not Phosphorylation Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.177 |
0.348 |
|
| 2019 |
Wang W, Grossauer S, Koeck K, Simonds E, Lu E, Bergers G, Weiss W, Petritsch C. Tmod-03. Gaining A Mechanistic Understanding Of Therapy Evasion From Dual Mapk Pathway Inhibition In A Syngeneic Brafv600E Mutant Cdkn2A Deleted Mouse Model To Preempt Resistance In Patients With Brafv600E Mutant Pediatric Glioma Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz036.242 |
0.689 |
|
| 2019 |
Zhang J, Liu K, Dik R, Yang X, Waanders A, Resnick A, Wright K, Weiss W, Haas-Kogan D, Mueller S. THER-34. MEK BLOCKADE SYNERGISTICALLY INCREASES THE ANTI-TUMOR EFFECTS OF mTOR INHIBITION IN GLIOMAS Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz036.238 |
0.416 |
|
| 2019 |
Zhao G, Muldoon D, Mo X, Tang C, Fu H, Gustafson WC, Weiss WA, Nicolaides T. Ther-17. Braf-V600E Degradation As A Therapeutic Strategy In Braf-V600E Mutant Gliomas Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz036.224 |
0.757 |
|
| 2019 |
Luo X, Fan Q, Shokat KM, Weiss WA. THER-08. RAPLINK-1 COOPERATES WITH INHIBITORS OF Bcl-2/Bcl-xl TO INDUCE APOPTOSIS IN GLIOBLASTOMA Neuro-Oncology. 21: ii115-ii115. DOI: 10.1093/Neuonc/Noz036.215 |
0.483 |
|
| 2019 |
Menard M, McHenry L, Nasholm N, Wong-Michalak S, Lu E, Simonds E, Gustafson WC, Weiss WA. Immu-06. Investigating Immunosuppressive Mechanisms In The Tumor Microenvironment Of High-Risk Neuroblastoma; An Immunocompetent, Mycn-Driven, Non-Germline Gem Model Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz036.127 |
0.8 |
|
| 2018 |
Andor N, Simonds EF, Czerwinski DK, Chen J, Grimes SM, Wood-Bouwens C, Zheng GXY, Kubit MA, Greer S, Weiss WA, Levy R, Ji HP. Single-cell RNA-Seq of lymphoma cancers reveals malignant B cell types and co-expression of T cell immune checkpoints. Blood. PMID 30591526 DOI: 10.1182/Blood-2018-08-862292 |
0.722 |
|
| 2018 |
Iniguez AB, Alexe G, Wang EJ, Roti G, Patel S, Chen L, Kitara S, Conway A, Robichaud AL, Stolte B, Bandopadhayay P, Goodale A, Pantel S, Lee Y, Cheff DM, ... ... Weiss WA, et al. Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling. Cancer Cell. 34: 922-938.e7. PMID 30537514 DOI: 10.1016/J.Ccell.2018.11.005 |
0.403 |
|
| 2018 |
Robbins DJ, Rodriguez-Blanco J, Li B, Shen C, Orton D, Collins SA, Kasahara N, Ayad N, McCrea HJ, Roussel MF, Weiss WA, Capobianco AJ, Long J, Yang F. A CK1α activator penetrates the brain, and shows efficacy against drug-resistant metastatic medulloblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30487124 DOI: 10.1158/1078-0432.Ccr-18-1319 |
0.552 |
|
| 2018 |
An Z, Knobbe-Thomsen CB, Wan X, Fan QW, Reifenberger G, Weiss WA. EGFR cooperates with EGFRvIII to recruit macrophages in glioblastoma. Cancer Research. PMID 30401716 DOI: 10.1158/0008-5472.Can-17-3551 |
0.357 |
|
| 2018 |
Aghaeepour N, Simonds EF, Knapp DJHF, Bruggner R, Sachs K, Culos A, Gherardini PF, Samusik N, Fragiadakis G, Bendall S, Gaudilliere B, Angst MS, Eaves CJ, Weiss WA, Fantl W, et al. GateFinder: Projection-based Gating Strategy Optimization for Flow and Mass Cytometry. Bioinformatics (Oxford, England). PMID 29850785 DOI: 10.1093/Bioinformatics/Bty430 |
0.696 |
|
| 2018 |
Pal S, Kozono D, Yang X, Fendler W, Fitts W, Ni J, Alberta JA, Zhao J, Liu KX, Bian J, Truffaux N, Weiss WA, Resnick AC, Bandopadhayay P, Ligon KL, et al. Dual HDAC and PI3K inhibition abrogates NFκB- and FOXM1-mediated DNA damage response to radiosensitize pediatric high-grade gliomas. Cancer Research. PMID 29760046 DOI: 10.1158/0008-5472.Can-17-3691 |
0.398 |
|
| 2018 |
Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, Tien AC, Sabo JK, Wang N, Chen I, Kloepper J, Larrouquere L, ... ... Weiss WA, et al. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. Cancer Cell. PMID 29681511 DOI: 10.1016/J.Ccell.2018.03.020 |
0.607 |
|
| 2018 |
Bolin S, Borgenvik A, Persson CU, Sundström A, Qi J, Bradner JE, Weiss WA, Cho YJ, Weishaupt H, Swartling FJ. Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma. Oncogene. PMID 29511348 DOI: 10.1038/S41388-018-0135-1 |
0.728 |
|
| 2018 |
Ferrucci V, de Antonellis P, Pennino FP, Asadzadeh F, Virgilio A, Montanaro D, Galeone A, Boffa I, Pisano I, Scognamiglio I, Navas L, Diana D, Pedone E, Gargiulo S, Gramanzini M, ... ... Weiss WA, et al. Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-β-OTX2-SNAIL via PTEN inhibition. Brain : a Journal of Neurology. PMID 29490009 DOI: 10.1093/Brain/Awy039 |
0.753 |
|
| 2018 |
Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, ... ... Weiss WA, et al. A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases. Cell. 172: 1050-1062.e14. PMID 29474906 DOI: 10.1016/J.Cell.2018.01.038 |
0.394 |
|
| 2018 |
Ilkhanizadeh S, Sabelström H, Miroshnikova YA, Frantz A, Zhu W, Idilli A, Lakins JN, Schmidt C, Quigley D, Fenster T, Yuan E, Trzeciak JR, Saxena S, Lindberg OR, Mouw J, ... ... Weiss WA, et al. Antisecretory Factor-mediated Inhibition of Cell Volume Dynamics Produces Anti-tumor Activity in Glioblastoma. Molecular Cancer Research : McR. PMID 29431617 DOI: 10.1158/1541-7786.Mcr-17-0413 |
0.826 |
|
| 2018 |
An Z, Aksoy O, Zheng T, Fan QW, Weiss WA. Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies. Oncogene. PMID 29321659 DOI: 10.1038/S41388-017-0045-7 |
0.351 |
|
| 2018 |
Simonds E, Lu E, McHenry L, Chuntova P, Okada H, Weiss W, Hellstrom M. Immu-04. Overcoming Immune Evasion In Glioblastoma Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy148.507 |
0.623 |
|
| 2018 |
Rodriguez Blanco J, Li B, Long J, Orthon D, Ayad N, MaCrea H, Roussel M, Weiss W, Capobianco A, Robbins D. DDIS-11. A CK1a ACTIVATOR PENETRATES THE BRAIN, AND SHOWS EFFICACY AGAINST DRUG-RESISTANT METASTATIC MEDULLOBLASTOMA Neuro-Oncology. 20: vi71-vi71. DOI: 10.1093/Neuonc/Noy148.290 |
0.478 |
|
| 2018 |
Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss W, Rodriguez C, Mehrdad N, Nguyen D, Ayad N, Rai P, Capobianco A, Robbins D. MBRS-64. SURPRISING ROLE FOR WNT SIGNALING IN SONIC HEDGEHOG DRIVEN MEDULLOBLASTOMA Neuro-Oncology. 20: i142-i142. DOI: 10.1093/Neuonc/Noy059.508 |
0.473 |
|
| 2018 |
Ferrucci V, Antonellis Pd, Pennino FP, Asadzadeh F, Siciliano R, Virgilio A, Galeone A, Martino LD, Quaglietta L, Errico ME, Donofrio V, Picard D, Remke M, Chesler L, Johansson FK, ... Weiss W, et al. Mbrs-52. Targeting Prune-1 In A Gemm Of Metastatic Medulloblastoma: A Potential Route Of Inhibition For New Future Therapies Neuro-Oncology. 20: 139-139. DOI: 10.1093/Neuonc/Noy059.497 |
0.595 |
|
| 2018 |
Pal S, Kozono D, Yang X, Fitts W, Ni J, Alberta J, Zhao J, Liu K, Bian J, Truffaux N, Weiss W, Resnick A, Bandhopadhayay P, Ligon K, DuBois S, et al. HGG-36. NFκB AND FOXM1 MEDIATE ANTI-CANCER ACTIVITY OF DUAL HDAC AND PI3K INHIBITION IN PEDIATRIC HIGH GRADE GLIOMA AND DIPG Neuro-Oncology. 20. DOI: 10.1093/Neuonc/Noy059.308 |
0.368 |
|
| 2018 |
Tailor J, Huang M, Smith A, Weiss W. A human iPS cell-based model of medulloblastoma demonstrates co-operativity between SHH signalling and mutation in an epigenetic modifier Neuro-Oncology. 20: i2-i3. DOI: 10.1093/neuonc/nox237.009 |
0.708 |
|
| 2017 |
Chen L, Alexe G, Dharia NV, Ross L, Iniguez AB, Conway AS, Wang EJ, Veschi V, Lam N, Qi J, Gustafson WC, Nasholm N, Vazquez F, Weir BA, Cowley GS, ... ... Weiss WA, et al. CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2. The Journal of Clinical Investigation. PMID 29202477 DOI: 10.1172/Jci90793 |
0.743 |
|
| 2017 |
Zheng T, Ménard M, Weiss WA. Neuroblastoma Metastases: Leveraging the Avian Neural Crest. Cancer Cell. 32: 395-397. PMID 29017050 DOI: 10.1016/J.Ccell.2017.09.012 |
0.352 |
|
| 2017 |
Jones DTW, Kieran MW, Bouffet E, Alexandrescu S, Bandopadhayay P, Bornhorst M, Ellison D, Fangusaro J, Fisher MI, Foreman N, Fouladi M, Hargrave D, Hawkins C, Jabado N, Massimino M, ... ... Weiss W, et al. Pediatric Low-Grade Gliomas: Next Biologically Driven Steps. Neuro-Oncology. PMID 29016845 DOI: 10.1093/Neuonc/Nox141 |
0.407 |
|
| 2017 |
Jahangiri A, Nguyen A, Chandra A, Sidorov MK, Yagnik G, Rick J, Han SW, Chen W, Flanigan PM, Schneidman-Duhovny D, Mascharak S, De Lay M, Imber B, Park CC, Matsumoto K, ... ... Weiss WA, et al. Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973887 DOI: 10.1073/Pnas.1701821114 |
0.301 |
|
| 2017 |
Zanca C, Villa GR, Benitez JA, Thorne AH, Koga T, D'Antonio M, Ikegami S, Ma J, Boyer AD, Banisadr A, Jameson NM, Parisian AD, Eliseeva OV, Barnabe GF, Liu F, ... ... Weiss WA, et al. Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity. Genes & Development. PMID 28724615 DOI: 10.1101/Gad.300079.117 |
0.399 |
|
| 2017 |
Levin VA, Abrey LE, Heffron TP, Tonge PJ, Dar AC, Weiss WA, Gallo JM. CNS Anticancer Drug Discovery and Development: 2016 conference insights. Cns Oncology. PMID 28718326 DOI: 10.2217/Cns-2017-0014 |
0.336 |
|
| 2017 |
Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss WA, Rodriguez C, Mehrdad N, Nguyen DM, Ayad NG, Rai P, Capobianco AJ, Robbins DJ. Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma. Oncogene. PMID 28714964 DOI: 10.1038/Onc.2017.232 |
0.628 |
|
| 2017 |
Fan QW, Nicolaides TP, Weiss WA. Inhibiting 4EBP1 in glioblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28696243 DOI: 10.1158/1078-0432.Ccr-17-0042 |
0.676 |
|
| 2017 |
Fan Q, Aksoy O, Wong RA, Ilkhanizadeh S, Novotny CJ, Gustafson WC, Truong AY, Cayanan G, Simonds EF, Haas-Kogan D, Phillips JJ, Nicolaides T, Okaniwa M, Shokat KM, Weiss WA. A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma. Cancer Cell. 31: 424-435. PMID 28292440 DOI: 10.1016/J.Ccell.2017.01.014 |
0.82 |
|
| 2017 |
Simonds E, Cayanan G, Park J, Bendall S, Nolan G, Weiss W. STEM-22. Single-cell mass cytometry of human glioblastoma reveals phenotypic heterogeneity and distinct cell cycle and epigenetic states among glioma stem cells Neuro-Oncology. 19: vi230-vi230. DOI: 10.1093/Neuonc/Nox168.937 |
0.734 |
|
| 2017 |
Sabelstrom H, Petri R, Shchors K, Jandial R, Sacheva R, Masic S, Yuan E, Fenster T, Nicolaides T, IIkhanizadeh S, Berger MS, Snyder E, Weiss W, Jakobsson J, Persson A. STEM-11. A MAPK-DRIVEN miR-124-SOX9 AXIS IS CRITICAL FOR STEM CELL MAINTENANCE, PROGRESSION, AND THERAPY-RESISTANCE IN GLIOBLASTOMA Neuro-Oncology. 19: vi228-vi228. DOI: 10.1093/Neuonc/Nox168.927 |
0.682 |
|
| 2017 |
Bolin S, Borgenvik A, Persson C, Sundström A, Qi J, Bradner J, Weiss W, Cho Y, Weishaupt H, Swartling F. PDTM-34. COMBINED BET BROMODOMAIN AND CDK2 INHIBITION IN MYC-DRIVEN MEDULLOBLASTOMA Neuro-Oncology. 19: vi197-vi197. DOI: 10.1093/Neuonc/Nox168.797 |
0.667 |
|
| 2017 |
Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss W, Rodriguez C, Merhdad N, Nguyen D, Ayad N, Rai P, Capobianco A, Robbins DJ. PDTM-03. SURPRISING ROLE FOR WNT SIGNALING IN Trp53-MUTANT SHH MEDULLOBLASTOMA Neuro-Oncology. 19: vi190-vi190. DOI: 10.1093/Neuonc/Nox168.768 |
0.471 |
|
| 2017 |
Liu KX, Mueller S, Dik R, Yang X, DuBois S, Waanders AJ, Resnick AC, Weiss WA, Haas-Kogan D. Exth-58. Effects Of Torc1/2 Inhibitor Mln0128 Alone And In Combination With Mek Inhibition In Braf Mutated Glioma Models In Vitro And In Vivo Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.350 |
0.364 |
|
| 2017 |
Schmidt C, Chen S, IIkhanizadeh S, Sabelstrom H, Yuan E, Ding A, Weiss W, Berger MS, Arkin M, Persson A. EXTH-55. REPURPOSING THERAPEUTICS IN PATIENT-DERIVED GLIOMAS AND AN IDH1 MUTANT GLIOMA MODEL Neuro-Oncology. 19: vi84-vi85. DOI: 10.1093/Neuonc/Nox168.347 |
0.535 |
|
| 2017 |
Sabelstrom H, IIkhanizadeh S, Miroshnikova YA, Frantz A, Zhu W, Idilli A, Quigley D, Fenster T, Yuan E, Saxena S, Mouw JK, Burdick JA, Magnitsky S, Berger MS, Arosio D, ... ... Weiss WA, et al. EXTH-23. ANTISECRETORY FACTOR-MEDIATED LOWERING OF INTERSTITIAL FLUID PRESSURE PRODUCES ANTI-TUMOR ACTIVITY IN GLIOBLASTOMA Neuro-Oncology. 19: vi77-vi77. DOI: 10.1093/Neuonc/Nox168.317 |
0.54 |
|
| 2017 |
Aksoy O, Fan Q, Shokat K, Ruggero D, Weiss W. CSIG-42. UNDERSTANDING THE ROLE OF TRANSLATIONAL CONTROL IN MYCN-DRIVEN MEDULLOBLASTOMA Neuro-Oncology. 19: vi58-vi58. DOI: 10.1093/Neuonc/Nox168.236 |
0.44 |
|
| 2017 |
Huang M, Tailor JK, Zhen Q, Nash EK, Phillips J, Morrissy S, Kool M, Pfister SM, Swartling FJ, Taylor MD, Smith A, Weiss WA. TMOD-11. HUMAN STEM CELL BASED MODEL OF MEDULLOBLASTOMA Neuro-Oncology. 19: vi256-vi257. DOI: 10.1093/Neuonc/Nox168.1050 |
0.788 |
|
| 2017 |
Huang M, Zheng T, Guo J, Sperring C, Miller M, McHenry L, Zhen Q, Moriarity B, Bronner M, Conklin B, Largaespada D, Maris J, Matthay K, Weiss W. TMOD-09. HUMAN PLURIPOTENT STEM CELL-BASED MODELS OF NEUROBLASTOMA Neuro-Oncology. 19: vi256-vi256. DOI: 10.1093/Neuonc/Nox168.1048 |
0.789 |
|
| 2017 |
Čančer M, Hutter S, Rosén G, Hellström A, Essand M, Huang M, Tailor J, Smith A, Weiss WA, Falk A, Weishaupt H, Swartling F. TMOD-05. MYCN OVEREXPRESSION AND STABILIZATION DRIVES MEDULLOBLASTOMA FROM HUMAN NEURO-EPITHELIAL STEM CELLS Neuro-Oncology. 19: vi255-vi255. DOI: 10.1093/Neuonc/Nox168.1044 |
0.788 |
|
| 2017 |
Jahangiri A, Sidorov M, Nguyen A, Yagnik G, Han SW, Mascharak S, Lay MD, Wagner J, Castro B, Imber B, Lu K, Bergers G, Weiss W, Aghi MK. Angi-12. Identification Of A Novel Tyrosine Kinase/Integrin Complex That Drives Brain Metastases Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.090 |
0.312 |
|
| 2017 |
Simonds E, Aghaeepour N, Cayanan G, Park J, Nolan G, Weiss W. HGG-21. IDENTIFICATION OF SMALL MOLECULE KINASE INHIBITORS WITH SPECIFIC ACTIVITY IN PEDIATRIC GLIOMA Neuro-Oncology. 19: iv27-iv27. DOI: 10.1093/Neuonc/Nox083.110 |
0.772 |
|
| 2016 |
Zhang J, Yao TW, Hashizume R, Hariono S, Barkovich KJ, Fan QW, Prados M, James CD, Weiss WA, Nicolaides T. Combined BRAF(V600E) and MEK blockade for BRAF(V600E)-mutant gliomas. Journal of Neuro-Oncology. PMID 27848137 DOI: 10.1007/S11060-016-2333-4 |
0.688 |
|
| 2016 |
Rinkenbaugh AL, Cogswell PC, Calamini B, Dunn DE, Persson AI, Weiss WA, Lo DC, Baldwin AS. IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance. Oncotarget. PMID 27732951 DOI: 10.18632/Oncotarget.12507 |
0.582 |
|
| 2016 |
Yao TW, Zhang J, Prados M, Weiss WA, James CD, Nicolaides T. Acquired resistance to BRAF inhibition in BRAFV600E mutant gliomas. Oncotarget. PMID 27611946 DOI: 10.18632/Oncotarget.11882 |
0.67 |
|
| 2016 |
Vaughan L, Clarke PA, Barker K, Chanthery Y, Gustafson CW, Tucker E, Renshaw J, Raynaud F, Li X, Burke R, Jamin Y, Robinson SP, Pearson A, Maira M, Weiss WA, et al. Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors. Oncotarget. PMID 27438153 DOI: 10.18632/Oncotarget.10544 |
0.841 |
|
| 2016 |
Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW, Powers S, Smith K, Aburi M, Iavarone A, Lasorella A, ... ... Weiss WA, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Molecular Cancer Research : McR. PMID 27401613 DOI: 10.1158/1541-7786.Mcr-16-0090 |
0.758 |
|
| 2016 |
Jones C, Karajannis MA, Jones DT, Kieran MW, Monje M, Baker SJ, Becher OJ, Cho YJ, Gupta N, Hawkins C, Hargrave D, Haas-Kogan DA, Jabado N, Li XN, Mueller S, ... ... Weiss WA, et al. Pediatric high-grade glioma: biologically and clinically in need of new thinking. Neuro-Oncology. PMID 27282398 DOI: 10.1093/Neuonc/Now101 |
0.797 |
|
| 2016 |
Olow A, Mueller S, Yang X, Hashizume R, Meyerowitz J, Weiss WA, Resnick AC, Waanders AJ, Stalpers LJ, Berger MS, Gupta N, James CD, Petritsch CK, Haas-Kogan DA. BRAF status in personalizing treatment approaches for pediatric gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27217440 DOI: 10.1158/1078-0432.Ccr-15-1101 |
0.781 |
|
| 2016 |
Huang M, Miller ML, McHenry LK, Zheng T, Zhen Q, Ilkhanizadeh S, Conklin BR, Bronner ME, Weiss WA. Generating trunk neural crest from human pluripotent stem cells. Scientific Reports. 6: 19727. PMID 26812940 DOI: 10.1038/Srep19727 |
0.787 |
|
| 2016 |
Dasgupta T, Olow AK, Yang X, Hashizume R, Nicolaides TP, Tom M, Aoki Y, Berger MS, Weiss WA, Stalpers LJ, Prados M, James CD, Mueller S, Haas-Kogan DA. Erratum to: Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma. Journal of Neuro-Oncology. PMID 26782702 DOI: 10.1007/S11060-015-2024-6 |
0.6 |
|
| 2016 |
Morrissy AS, Garzia L, Shih DJ, Zuyderduyn S, Huang X, Skowron P, Remke M, Cavalli FM, Ramaswamy V, Lindsay PE, Jelveh S, Donovan LK, Wang X, Luu B, Zayne K, ... ... Weiss WA, et al. Divergent clonal selection dominates medulloblastoma at recurrence. Nature. PMID 26760213 DOI: 10.1038/Nature16478 |
0.336 |
|
| 2016 |
Bolin S, Borgenvik A, Persson C, Rosén G, Sundström A, Qi J, Bradner JE, Weiss WA, Cho Y, Weishaupt H, Swartling FJ. Abstract 2473: Combined BET-bromodomain and CDK2 inhibition in MYC-driven medulloblastoma Cancer Research. 76: 2473-2473. DOI: 10.1158/1538-7445.Am2016-2473 |
0.739 |
|
| 2016 |
Sabelstrom H, Jandial R, Shchors K, Masic S, Yuan E, Fenster T, Saxena S, Ho A, Nicolaides TP, Wong R, Yakovenko S, Berger MH, Snyder EY, Jakobsson J, Weiss WA, et al. Abstract 1916: Targeting a MAPK-miR-124-Sox9 axis radiosensitizes human glioblastoma cells Cancer Research. 76: 1916-1916. DOI: 10.1158/1538-7445.Am2016-1916 |
0.678 |
|
| 2015 |
Meyerowitz JG, Weiss WA, Gustafson WC. A new "angle" on kinase inhibitor design: Prioritizing amphosteric activity above kinase inhibition. Molecular & Cellular Oncology. 2: e975641. PMID 27308435 DOI: 10.4161/23723556.2014.975641 |
0.797 |
|
| 2015 |
Yu D, Dong Z, Gustafson WC, Ruiz-González R, Signor L, Marzocca F, Borel F, Klassen MP, Makhijani K, Royant A, Jan YN, Weiss WA, Guo S, Shu X. Rational design of a monomeric and photostable far-red fluorescent protein for fluorescence imaging in vivo. Protein Science : a Publication of the Protein Society. PMID 26549191 DOI: 10.1002/Pro.2843 |
0.656 |
|
| 2015 |
Dasgupta T, Olow AK, Yang X, Hashizume R, Tom M, Aoki Y, Berger MS, Weiss WA, Stalpers LJ, Prados M, David James C, Mueller S, Haas-Kogan DA. Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma. Journal of Neuro-Oncology. PMID 26384810 DOI: 10.1007/S11060-015-1939-2 |
0.458 |
|
| 2015 |
Lau J, Ilkhanizadeh S, Wang S, Miroshnikova YA, Salvatierra NA, Wong RA, Schmidt C, Weaver VM, Weiss WA, Persson AI. STAT3 blockade inhibits radiation-induced malignant progression in glioma. Cancer Research. PMID 26282165 DOI: 10.1158/0008-5472.Can-14-3331 |
0.816 |
|
| 2015 |
Huang X, He Y, Dubuc AM, Hashizume R, Zhang W, Reimand J, Yang H, Wang TA, Stehbens SJ, Younger S, Barshow S, Zhu S, Cooper MK, Peacock J, Ramaswamy V, ... ... Weiss WA, et al. EAG2 potassium channel with evolutionarily conserved function as a brain tumor target. Nature Neuroscience. PMID 26258683 DOI: 10.1038/Nn.4088 |
0.339 |
|
| 2015 |
Cage TA, Chanthery Y, Chesler L, Grimmer M, Knight Z, Shokat K, Weiss WA, Gustafson WC. Downregulation of MYCN through PI3K Inhibition in Mouse Models of Pediatric Neural Cancer. Frontiers in Oncology. 5: 111. PMID 26029667 DOI: 10.3389/Fonc.2015.00111 |
0.824 |
|
| 2015 |
Yao TW, Zhang J, Prados M, Weiss WA, James CD, Nicolaides T. EGFR blockade prevents glioma escape from BRAFV600E targeted therapy. Oncotarget. PMID 26023796 DOI: 10.18632/Oncotarget.4014 |
0.688 |
|
| 2015 |
Chen J, Hackett CS, Zhang S, Song YK, Bell RJ, Molinaro AM, Quigley DA, Balmain A, Song JS, Costello JF, Gustafson WC, Van Dyke T, Kwok PY, Khan J, Weiss WA. The genetics of splicing in neuroblastoma. Cancer Discovery. 5: 380-95. PMID 25637275 DOI: 10.1158/2159-8290.Cd-14-0892 |
0.798 |
|
| 2015 |
Hill RM, Kuijper S, Lindsey JC, Petrie K, Schwalbe EC, Barker K, Boult JK, Williamson D, Ahmad Z, Hallsworth A, Ryan SL, Poon E, Robinson SP, Ruddle R, Raynaud FI, ... ... Weiss WA, et al. Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease. Cancer Cell. 27: 72-84. PMID 25533335 DOI: 10.1016/J.Ccell.2014.11.002 |
0.77 |
|
| 2015 |
Li N, Maly DJ, Chanthery YH, Sirkis DW, Nakamura JL, Berger MS, James CD, Shokat KM, Weiss WA, Persson AI. Radiotherapy followed by aurora kinase inhibition targets tumor-propagating cells in human glioblastoma. Molecular Cancer Therapeutics. 14: 419-28. PMID 25522764 DOI: 10.1158/1535-7163.Mct-14-0526 |
0.835 |
|
| 2015 |
Chen J, Weiss WA. Alternative splicing in cancer: implications for biology and therapy Oncogene. 34: 1-14. PMID 24441040 DOI: 10.1038/Onc.2013.570 |
0.644 |
|
| 2015 |
Cage TA, Chanthery Y, Chesler L, Grimmer M, Knight Z, Shokat K, Weiss WA, Gustafson WC. Downregulation of MYCN through PI3K inhibition in mouse models of pediatric neural cancer Frontiers in Oncology. 5. DOI: 10.3389/fonc.2015.00111 |
0.797 |
|
| 2015 |
Olow AK, Mueller S, Yang X, Hashizume R, Weiss W, Resnick AC, Sievert AJ, Berger MS, Gupta N, James DC, Haas-Kogan DA. Abstract B42: Targeting PI3K in personalized treatment of BRAF-mutated pediatric low-grade gliomas Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-B42 |
0.504 |
|
| 2015 |
Wu X, Dubuc A, Weiss WA, Wechsler-Reya RJ, Taylor MD. Abstract A46: Transcriptome analysis on tumor and its normal cerebellar counterpart from mouse models reveals molecular mechanisms underlying evolution of SHH and Group3 medulloblastoma Brain. 75. DOI: 10.1158/1538-7445.Brain15-A46 |
0.44 |
|
| 2015 |
Huang M, McHenry LK, Miller ML, Kim GE, Moriarity BS, Miyaoka Y, Bronner ME, Largaespada DA, Conklin BR, Ji HP, Maris JM, Matthay KK, Weiss WA. Abstract 3230: Human stem cell-based model of MYCN-driven neuroblastoma Cancer Research. 75: 3230-3230. DOI: 10.1158/1538-7445.Am2015-3230 |
0.788 |
|
| 2015 |
Simonds EF, Nolan GP, Weiss WA. Abstract 2313: Characterizing intratumoral cellular heterogeneity in human glioblastoma xenografts by 30+ parameter single-cell mass cytometry Cancer Research. 75: 2313-2313. DOI: 10.1158/1538-7445.Am2015-2313 |
0.774 |
|
| 2015 |
Griveau A, Shelton S, Tien A, Seano G, Yuen T, Sabo J, Lau J, Jahangiri A, Huillard E, Phillips J, Persson A, Oldham M, Weiss W, Aghi M, Stiles C, et al. ANGI-04Olig2 REGULATES Wnt7b EXPRESSION AND VASCULATURE CHARACTERISTICS IN GLIOMA Neuro-Oncology. 17: v41.4-v41. DOI: 10.1093/Neuonc/Nov207.04 |
0.808 |
|
| 2015 |
Fan Q, Wong R, Novotny C, Okaniwa M, Nicolaides T, Shokat K, Weiss W. ATPS-94THIRD GENERATION mTOR INHIBITORS IN GLIOBLASTOMA Neuro-Oncology. 17: v39.2-v39. DOI: 10.1093/Neuonc/Nov204.94 |
0.719 |
|
| 2015 |
Iikhanizadeh S, Miroshnikova Y, Frantz A, Zhu W, Idilli A, Quigley D, Lakins J, Magnitsky S, Phillips J, James D, Berger M, Arosio D, Sun D, Weaver V, Weiss W, et al. ATPS-63OSMOTIC SWELLING REGULATES TUMOR GROWTH AND DRUG UPTAKE IN HUMAN GLIOBLASTOMA Neuro-Oncology. 17: v32.1-v32. DOI: 10.1093/Neuonc/Nov204.63 |
0.629 |
|
| 2015 |
Mueller S, Dik R, Yang X, Aleksandra O, Gustafson C, DuBois S, Weiss W, Waanders A, Resnick A, Haas-Kogan D. Lg-06Effects Of Torc1/2 Inhibitor Mln0128 Alone And In Combination With Mek Inhibition In Braf Mutated Glioma Cells Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov061.75 |
0.455 |
|
| 2015 |
Sabelstrom H, Jandial R, Shchors K, Masic S, Ho A, Vandenberg S, Nicolaides TP, Nguyen K, Yakovenko S, Prados MD, James CD, Berger MS, Evan GI, Snyder EY, Weiss WA, et al. HG-13 * SOX9 AS A DOWN-STREAM TARGET IN RAS/MEK-DRIVEN PEDIATRIC GLIOMA Neuro-Oncology. 17: iii13-iii13. DOI: 10.1093/Neuonc/Nov061.50 |
0.661 |
|
| 2015 |
Olow AK, Mueller S, Yang X, Hashizume R, Meyerowitz J, Weiss W, Resnick AC, Waanders AJ, Berger MS, Gupta N, James CD, Haas-Kogan DA. TR-08 * TARGETED COMBINATORIAL APPROACH FOR TREATMENT OF PEDIATRIC LOW GRADE GLIOMAS IN THE CONTEXT OF BRAFV600E AND KIAA1549:BRAF MUTATIONS Neuro-Oncology. 17: iii38-iii38. DOI: 10.1093/Neuonc/Nov061.153 |
0.81 |
|
| 2015 |
Yao T, Zhang J, Prados M, Weiss W, James D, Nicolaides T. SG-01 * FEEDBACK ACTIVATION OF EGFR VIA PTPN9 LEADS TO GLIOMA ESCAPE FROM BRAFV600E TARGETED THERAPY Neuro-Oncology. 17: iii34-iii35. DOI: 10.1093/Neuonc/Nov061.139 |
0.69 |
|
| 2014 |
Zhukova N, Ramaswamy V, Remke M, Martin DC, Castelo-Branco P, Zhang CH, Fraser M, Tse K, Poon R, Shih DJ, Baskin B, Ray PN, Bouffet E, Dirks P, von Bueren AO, ... ... Weiss WA, et al. WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma. Acta Neuropathologica Communications. 2: 174. PMID 25539912 DOI: 10.1186/S40478-014-0174-Y |
0.364 |
|
| 2014 |
Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, ... ... Weiss WA, et al. Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma. Cell Reports. 9: 1034-46. PMID 25437558 DOI: 10.1016/J.Celrep.2014.09.046 |
0.808 |
|
| 2014 |
Gustafson WC, Meyerowitz JG, Nekritz EA, Chen J, Benes C, Charron E, Simonds EF, Seeger R, Matthay KK, Hertz NT, Eilers M, Shokat KM, Weiss WA. Drugging MYCN through an allosteric transition in Aurora kinase A. Cancer Cell. 26: 414-27. PMID 25175806 DOI: 10.1016/J.Ccr.2014.07.015 |
0.789 |
|
| 2014 |
Chen J, Weiss WA. When deletions gain functions: commandeering epigenetic mechanisms. Cancer Cell. 26: 160-1. PMID 25117708 DOI: 10.1016/J.Ccr.2014.07.021 |
0.645 |
|
| 2014 |
Ilkanizadeh S, Lau J, Huang M, Foster DJ, Wong R, Frantz A, Wang S, Weiss WA, Persson AI. Glial progenitors as targets for transformation in glioma. Advances in Cancer Research. 121: 1-65. PMID 24889528 DOI: 10.1016/B978-0-12-800249-0.00001-9 |
0.808 |
|
| 2014 |
Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X. An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging. Nature Communications. 5: 3626. PMID 24832154 DOI: 10.1038/Ncomms4626 |
0.658 |
|
| 2014 |
Weller M, Kaulich K, Hentschel B, Felsberg J, Gramatzki D, Pietsch T, Simon M, Westphal M, Schackert G, Tonn JC, von Deimling A, Davis T, Weiss WA, Loeffler M, Reifenberger G, et al. Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy. International Journal of Cancer. Journal International Du Cancer. 134: 2437-47. PMID 24614983 DOI: 10.1002/Ijc.28576 |
0.314 |
|
| 2014 |
Marshall GM, Carter DR, Cheung BB, Liu T, Mateos MK, Meyerowitz JG, Weiss WA. The prenatal origins of cancer. Nature Reviews. Cancer. 14: 277-89. PMID 24599217 DOI: 10.1038/Nrc3679 |
0.747 |
|
| 2014 |
Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, Stütz AM, Wang X, Gallo M, Garzia L, Zayne K, Zhang X, Ramaswamy V, Jäger N, Jones DT, Sill M, ... ... Weiss WA, et al. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature. 506: 445-50. PMID 24553142 DOI: 10.1038/Nature13108 |
0.324 |
|
| 2014 |
Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, Fouse SD, Yamamoto S, Ueda H, Tatsuno K, Asthana S, Jalbert LE, Nelson SJ, Bollen AW, Gustafson WC, ... ... Weiss WA, et al. Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science (New York, N.Y.). 343: 189-93. PMID 24336570 DOI: 10.1126/Science.1239947 |
0.729 |
|
| 2014 |
Bandopadhayay P, Bergthold G, Nguyen B, Schubert S, Gholamin S, Tang Y, Bolin S, Schumacher SE, Zeid R, Masoud S, Yu F, Vue N, Gibson WJ, Paolella BR, Mitra SS, ... ... Weiss WA, et al. BET bromodomain inhibition of MYC-amplified medulloblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 912-25. PMID 24297863 DOI: 10.1158/1078-0432.Ccr-13-2281 |
0.705 |
|
| 2014 |
Gottardo NG, Hansford JR, McGlade JP, Alvaro F, Ashley DM, Bailey S, Baker DL, Bourdeaut F, Cho YJ, Clay M, Clifford SC, Cohn RJ, Cole CH, Dallas PB, Downie P, ... ... Weiss WA, et al. Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group. Acta Neuropathologica. 127: 189-201. PMID 24264598 DOI: 10.1007/S00401-013-1213-7 |
0.321 |
|
| 2014 |
Gustafson WC, Meyerowitz JG, Nekritz EA, Charron E, Matthay KK, Hertz NT, Eilers M, Shokat KM, Weiss WA. Abstract PR08: Drugging MYCN protein stability through an allosteric transition in Aurora kinase A Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-Pr08 |
0.809 |
|
| 2014 |
Meyerowitz JG, Gustafson WC, Nekritz E, Swartling F, Shokat KM, Ruggero D, Weiss WA. Abstract B78: Targeting the translational apparatus in MYCN-driven medulloblastoma Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-B78 |
0.831 |
|
| 2014 |
Batra V, Chacko A, Gagliardi M, Hou C, Mikitsh JL, Freifelder RH, Kachur A, LeGeyt BC, Schmitz A, Toto L, Vaidyanathan G, Zalutsky MR, Matthay KK, Weiss WA, Gustafson WC, et al. Abstract B48: Preclinical development of meta-[211At] astatobenzylguanidine ([211At] MABG) targeted radiotherapy for neuroblastoma Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-B48 |
0.731 |
|
| 2014 |
Hill RM, Kuijper S, Lindsey J, Schwalbe EC, Barker K, Boult J, Williamson D, Ahmad Z, Hallsworth A, Ryan S, Poon E, Robinson S, Ruddle R, Raynaud F, Howell L, ... ... Weiss WA, et al. MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-201 |
0.774 |
|
| 2014 |
Chen J, Hackett CS, Zhang S, Song YK, Molinaro A, Quigley DA, Balmain A, Gustafson WC, Dyke TAV, Kwok P, Khan J, Weiss WA. Abstract 3413: A genetic analysis of splicing in neuroblastoma identifies opposing functions for FUBP1 splice variants in MYC regulation Cancer Research. 74: 3413-3413. DOI: 10.1158/1538-7445.Am2014-3413 |
0.801 |
|
| 2014 |
Bolin SM, Lau J, Chen J, Savov V, Persson AI, Hede S, Weiss WA, Swartling F. Abstract 3100: Glial origin for MYCN-driven medulloblastoma and targeted prosenescence therapies Cancer Research. 74: 3100-3100. DOI: 10.1158/1538-7445.Am2014-3100 |
0.839 |
|
| 2014 |
Gustafson WC, Meyerowitz JG, Nekritz EA, Charron EA, Chanthery Y, Simonds E, Matthay K, Hertz N, Shokat K, Weiss WA. Abstract 2688: Drugging MYCN through an allosteric transition in Aurora A kinase Cancer Research. 74: 2688-2688. DOI: 10.1158/1538-7445.Am2014-2688 |
0.8 |
|
| 2014 |
Ilkhanizadeh S, Miroshnikova Y, Frantz A, James D, Berger M, McKnight T, Weaver V, Weiss W, Persson A. NT-11 * TARGETING INTERSTITIAL FLUID PRESSURE TO REDUCE TUMOR GROWTH AND INCREASE DRUG UPTAKE IN BRAIN TUMORS Neuro-Oncology. 16: v161-v161. DOI: 10.1093/Neuonc/Nou265.11 |
0.832 |
|
| 2014 |
Weiss W, Fan Q, Baldwin A, Wong R, Shokat K. ET-63 * TARGETING THE EGFR-STAT-NF- B AXIS IN GLIOBLASTOMA Neuro-Oncology. 16: v93-v93. DOI: 10.1093/Neuonc/Nou255.60 |
0.555 |
|
| 2014 |
Persson AI, Ilkhanizadeh S, Miroshnikova YA, Frantz A, Lakins JN, James CD, McKnight TR, Berger MS, Bergers G, Weiss WA, Weaver VM. HIGH INTERSTITIAL FLUID PRESSURE REGULATES TUMOR GROWTH AND DRUG UPTAKE IN HUMAN GLIOBLASTOMA Neuro-Oncology. 16: iii32-iii32. DOI: 10.1093/Neuonc/Nou208.37 |
0.823 |
|
| 2014 |
Weiss WA, Wong R, Fan Q, Ilkhanizadeh S, Lu M, Beyer J, Dube N, Forsayeth J, Kells A, Xu T, Bankiewicz K, Ducker G, Feldman M, Shokat K. MTOR KINASE INHIBITORS AND APOPTOSIS IN GLIOBLASTOMA Neuro-Oncology. 16: iii31-iii31. DOI: 10.1093/Neuonc/Nou208.31 |
0.829 |
|
| 2014 |
Vaidyanathan G, Gururangan S, Bigner D, Zalutsky M, Morfouace M, Shelat A, Megan J, Freeman BB, Robinson S, Throm S, Olson JM, Li X, Guy KR, Robinson G, Stewart C, ... ... Weiss W, ... ... Weiss W, et al. MEDULLOBLASTOMA Neuro-Oncology. 16: i71-i96. DOI: 10.1093/Neuonc/Nou074 |
0.731 |
|
| 2013 |
Remke M, Ramaswamy V, Peacock J, Shih DJ, Koelsche C, Northcott PA, Hill N, Cavalli FM, Kool M, Wang X, Mack SC, Barszczyk M, Morrissy AS, Wu X, Agnihotri S, ... ... Weiss WA, et al. TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. Acta Neuropathologica. 126: 917-29. PMID 24174164 DOI: 10.1007/S00401-013-1198-2 |
0.336 |
|
| 2013 |
Fan QW, Cheng CK, Gustafson WC, Charron E, Zipper P, Wong RA, Chen J, Lau J, Knobbe-Thomsen C, Weller M, Jura N, Reifenberger G, Shokat KM, Weiss WA. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma. Cancer Cell. 24: 438-49. PMID 24135280 DOI: 10.1016/J.Ccr.2013.09.004 |
0.804 |
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| 2013 |
Diede SJ, Yao Z, Keyes CC, Tyler AE, Dey J, Hackett CS, Elsaesser K, Kemp CJ, Neiman PE, Weiss WA, Olson JM, Tapscott SJ. Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1254-60. PMID 24107773 DOI: 10.4161/Epi.26486 |
0.733 |
|
| 2013 |
Jahangiri A, Weiss WA. It takes two to tango: Dual inhibition of PI3K and MAPK in rhabdomyosarcoma Clinical Cancer Research. 19: 5811-5813. PMID 24097859 DOI: 10.1158/1078-0432.Ccr-13-2177 |
0.365 |
|
| 2013 |
Huang M, Weiss WA. Neuroblastoma and MYCN. Cold Spring Harbor Perspectives in Medicine. 3: a014415. PMID 24086065 DOI: 10.1101/Cshperspect.A014415 |
0.749 |
|
| 2013 |
Ilkhanizadeh S, Weiss WA. Starvation favors glioma stem cells. Nature Neuroscience. 16: 1359-61. PMID 24067285 DOI: 10.1038/Nn.3524 |
0.766 |
|
| 2013 |
Sun Y, Dong Z, Jin T, Ang KH, Huang M, Haston KM, Peng J, Zhong TP, Finkbeiner S, Weiss WA, Arkin MR, Jan LY, Guo S. Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. Elife. 2: e00508. PMID 24040509 DOI: 10.7554/Elife.00508 |
0.736 |
|
| 2013 |
Kreitzer FR, Salomonis N, Sheehan A, Huang M, Park JS, Spindler MJ, Lizarraga P, Weiss WA, So PL, Conklin BR. A robust method to derive functional neural crest cells from human pluripotent stem cells. American Journal of Stem Cells. 2: 119-31. PMID 23862100 |
0.728 |
|
| 2013 |
He K, Qi Q, Chan CB, Xiao G, Liu X, Tucker-Burden C, Wang L, Mao H, Lu X, McDonald FE, Luo H, Fan QW, Weiss WA, Sun SY, Brat DJ, et al. Blockade of glioma proliferation through allosteric inhibition of JAK2. Science Signaling. 6: ra55. PMID 23838182 DOI: 10.1126/Scisignal.2003900 |
0.434 |
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| 2013 |
Zhukova N, Ramaswamy V, Remke M, Pfaff E, Shih DJ, Martin DC, Castelo-Branco P, Baskin B, Ray PN, Bouffet E, von Bueren AO, Jones DT, Northcott PA, Kool M, Sturm D, ... ... Weiss WA, et al. Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2927-35. PMID 23835706 DOI: 10.1200/Jco.2012.48.5052 |
0.347 |
|
| 2013 |
Huang M, Weiss WA. G34, another connection between MYCN and a pediatric tumor. Cancer Discovery. 3: 484-6. PMID 23658294 DOI: 10.1158/2159-8290.Cd-13-0126 |
0.729 |
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| 2013 |
Chin L, De Sauvage F, Egeblad M, Olive KP, Tuveson D, Weiss W. Recapitulating human cancer in a mouse Nature Biotechnology. 31: 392-395. PMID 23657389 DOI: 10.1038/Nbt.2575 |
0.311 |
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| 2013 |
Shchors K, Persson AI, Rostker F, Tihan T, Lyubynska N, Li N, Swigart LB, Berger MS, Hanahan D, Weiss WA, Evan GI. Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy. Proceedings of the National Academy of Sciences of the United States of America. 110: E1480-9. PMID 23542378 DOI: 10.1073/Pnas.1219142110 |
0.559 |
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| 2013 |
Teitz T, Inoue M, Valentine MB, Zhu K, Rehg JE, Zhao W, Finkelstein D, Wang YD, Johnson MD, Calabrese C, Rubinstein M, Hakem R, Weiss WA, Lahti JM. Th-MYCN mice with caspase-8 deficiency develop advanced neuroblastoma with bone marrow metastasis. Cancer Research. 73: 4086-97. PMID 23536557 DOI: 10.1158/0008-5472.Can-12-2681 |
0.376 |
|
| 2013 |
Puissant A, Frumm SM, Alexe G, Bassil CF, Qi J, Chanthery YH, Nekritz EA, Zeid R, Gustafson WC, Greninger P, Garnett MJ, Mcdermott U, Benes CH, Kung AL, Weiss WA, et al. Targeting MYCN in neuroblastoma by BET bromodomain inhibition Cancer Discovery. 3: 309-323. PMID 23430699 DOI: 10.1158/2159-8290.Cd-12-0418 |
0.815 |
|
| 2013 |
Dubuc AM, Remke M, Korshunov A, Northcott PA, Zhan SH, Mendez-Lago M, Kool M, Jones DT, Unterberger A, Morrissy AS, Shih D, Peacock J, Ramaswamy V, Rolider A, Wang X, ... ... Weiss WA, et al. Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. Acta Neuropathologica. 125: 373-84. PMID 23184418 DOI: 10.1007/S00401-012-1070-9 |
0.342 |
|
| 2013 |
Swartling FJ, Hede SM, Weiss WA. What underlies the diversity of brain tumors? Cancer Metastasis Reviews. 32: 5-24. PMID 23085857 DOI: 10.1007/S10555-012-9407-3 |
0.694 |
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| 2013 |
Sun Y, Dong Z, Jin T, Ang K, Huang M, Haston KM, Peng J, Zhong TP, Finkbeiner S, Weiss WA, Arkin MR, Jan LY, Guo S. Author response: Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells Elife. DOI: 10.7554/Elife.00508.017 |
0.718 |
|
| 2013 |
He K, Qi Q, Chan C, Xiao G, Liu X, Tucker-Burden C, Wang L, Mao H, Lu X, McDonald FE, Luo H, Fan Q, Weiss WA, Sun S, Brat DJ, et al. Abstract 5683: Blockade of glioma proliferation via allosteric inhibition of JAK2. Cancer Research. 73: 5683-5683. DOI: 10.1158/1538-7445.Am2013-5683 |
0.477 |
|
| 2013 |
Puissant A, Frumm SM, Alexe G, Bassil CF, Qi J, Chanthery YH, Nekritz EA, Zeid R, Gustafson WC, Greninger P, Garnett MJ, McDermott U, Benes CH, Kung AL, Weiss WA, et al. Abstract 4622: Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition. Cancer Research. 73: 4622-4622. DOI: 10.1158/1538-7445.Am2013-4622 |
0.82 |
|
| 2013 |
Bolin S, Lau J, Savov V, Chen J, Persson AI, Hede S, Weiss WA, Swartling FJ. Abstract 357: A glial origin for medulloblastoma and inhibition of MYCN stabilization. Cancer Research. 73: 357-357. DOI: 10.1158/1538-7445.Am2013-357 |
0.832 |
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| 2013 |
Haas-Kogan D, Phillips JJ, Molinaro A, Wahl M, Mueller S, Weiss WA, Lupo JM, Berger MS, Prados MD, Butowski N, Clarke J, Perry A, Nelson SJ, Chang S. Abstract 3520: Imaging parameters and molecular correlates as predictive markers of treatment response to mTOR inhibition in adults with recurrent low-grade gliomas. Cancer Research. 73: 3520-3520. DOI: 10.1158/1538-7445.Am2013-3520 |
0.365 |
|
| 2013 |
Aaberg-Jessen C, Fogh L, Halle B, Jensen V, Brunner N, Kristensen BW, Abe T, Momii Y, Watanabe J, Morisaki I, Natsume A, Wakabayashi T, Fujiki M, Aldaz B, Fabius AWM, ... ... Weiss WA, et al. EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 15: iii37-iii61. DOI: 10.1093/Neuonc/Not176 |
0.571 |
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| 2013 |
Agarwal M, Nitta R, Dovat S, Li G, Arita H, Narita Y, Fukushima S, Tateishi K, Matsushita Y, Yoshida A, Miyakita Y, Ohno M, Collins VP, Kawahara N, Shibui S, ... ... Weiss W, et al. CELL BIOLOGY AND SIGNALING Neuro-Oncology. 15: iii12-iii31. DOI: 10.1093/Neuonc/Not174 |
0.761 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Weiss WA, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.75 |
|
| 2012 |
Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, et al. Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes & Development. 26: 1780-96. PMID 22855790 DOI: 10.1101/Gad.193789.112 |
0.825 |
|
| 2012 |
Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, ... ... Weiss WA, et al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 488: 49-56. PMID 22832581 DOI: 10.1038/Nature11327 |
0.335 |
|
| 2012 |
Cheng CK, Gustafson WC, Charron E, Houseman BT, Zunder E, Goga A, Gray NS, Pollok B, Oakes SA, James CD, Shokat KM, Weiss WA, Fan QW. Dual blockade of lipid and cyclin-dependent kinases induces synthetic lethality in malignant glioma. Proceedings of the National Academy of Sciences of the United States of America. 109: 12722-7. PMID 22802621 DOI: 10.1073/Pnas.1202492109 |
0.77 |
|
| 2012 |
Mueller S, Phillips J, Onar-Thomas A, Romero E, Zheng S, Wiencke JK, McBride SM, Cowdrey C, Prados MD, Weiss WA, Berger MS, Gupta N, Haas-Kogan DA. PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome. Neuro-Oncology. 14: 1146-52. PMID 22753230 DOI: 10.1093/Neuonc/Nos140 |
0.35 |
|
| 2012 |
Swartling FJ, Savov V, Persson AI, Chen J, Hackett CS, Northcott PA, Grimmer MR, Lau J, Chesler L, Perry A, Phillips JJ, Taylor MD, Weiss WA. Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC. Cancer Cell. 21: 601-13. PMID 22624711 DOI: 10.1016/J.Ccr.2012.04.012 |
0.807 |
|
| 2012 |
Barkovich KJ, Hariono S, Garske AL, Zhang J, Blair JA, Fan QW, Shokat KM, Nicolaides T, Weiss WA. Kinetics of inhibitor cycling underlie therapeutic disparities between EGFR-driven lung and brain cancers. Cancer Discovery. 2: 450-7. PMID 22588882 DOI: 10.1158/2159-8290.Cd-11-0287 |
0.699 |
|
| 2012 |
Huillard E, Hashizume R, Phillips JJ, Griveau A, Ihrie RA, Aoki Y, Nicolaides T, Perry A, Waldman T, McMahon M, Weiss WA, Petritsch C, James CD, Rowitch DH. Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. Proceedings of the National Academy of Sciences of the United States of America. 109: 8710-5. PMID 22586120 DOI: 10.1073/Pnas.1117255109 |
0.664 |
|
| 2012 |
Stauffer JK, Orentas RJ, Lincoln E, Khan T, Salcedo R, Hixon JA, Back TC, Wei JS, Patidar R, Song Y, Hurd L, Tsokos M, Lai EW, Eisenhofer G, Weiss W, et al. High-throughput molecular and histopathologic profiling of tumor tissue in a novel transplantable model of murine neuroblastoma: new tools for pediatric drug discovery. Cancer Investigation. 30: 343-63. PMID 22571338 DOI: 10.3109/07357907.2012.664670 |
0.403 |
|
| 2012 |
Seo Y, Gustafson WC, Dannoon SF, Nekritz EA, Lee CL, Murphy ST, VanBrocklin HF, Hernandez-Pampaloni M, Haas-Kogan DA, Weiss WA, Matthay KK. Tumor dosimetry using [124I]m-iodobenzylguanidine microPET/CT for [131I]m-iodobenzylguanidine treatment of neuroblastoma in a murine xenograft model. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 14: 735-42. PMID 22382618 DOI: 10.1007/S11307-012-0552-4 |
0.787 |
|
| 2012 |
Dubuc AM, Morrissy AS, Kloosterhof NK, Northcott PA, Yu EP, Shih D, Peacock J, Grajkowska W, van Meter T, Eberhart CG, Pfister S, Marra MA, Weiss WA, Scherer SW, Rutka JT, et al. Subgroup-specific alternative splicing in medulloblastoma. Acta Neuropathologica. 123: 485-99. PMID 22358458 DOI: 10.1007/S00401-012-0959-7 |
0.315 |
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| 2012 |
Lau J, Schmidt C, Markant SL, Taylor MD, Wechsler-Reya RJ, Weiss WA. Matching mice to malignancy: molecular subgroups and models of medulloblastoma. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 28: 521-32. PMID 22315164 DOI: 10.1007/S00381-012-1704-1 |
0.771 |
|
| 2012 |
Chanthery YH, Gustafson WC, Itsara M, Persson A, Hackett CS, Grimmer M, Charron E, Yakovenko S, Kim G, Matthay KK, Weiss WA. Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma. Science Translational Medicine. 4: 115ra3. PMID 22218692 DOI: 10.1126/scitranslmed.3002977 |
0.83 |
|
| 2012 |
Korshunov A, Remke M, Kool M, Hielscher T, Northcott PA, Williamson D, Pfaff E, Witt H, Jones DTW, Ryzhova M, Cho YJ, Wittmann A, Benner A, Weiss WA, Von Deimling A, et al. Biological and clinical heterogeneity of MYCN-amplified medulloblastoma Acta Neuropathologica. 123: 515-527. PMID 22160402 DOI: 10.1007/S00401-011-0918-8 |
0.403 |
|
| 2012 |
Fan QW, Weiss WA. Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors. Methods in Molecular Biology (Clifton, N.J.). 821: 349-59. PMID 22125077 DOI: 10.1007/978-1-61779-430-8_22 |
0.413 |
|
| 2012 |
Witt H, Mack SC, Bender S, Ryzhova M, Martin S, Isserlin R, Jones DTW, Northcott PA, Till M, Remke M, Benner A, Hielscher T, Gupta N, Garcia L, Weiss WA, et al. Abstract 1432: The heterogeneous genomic landscape of posterior fossa ependymoma Cancer Research. 72: 1432-1432. DOI: 10.1158/1538-7445.Am2012-1432 |
0.39 |
|
| 2012 |
Mack SC, Witt H, Shih D, Zuyderduyn S, Dubuc AM, Koster J, Northcott PA, Bertrand KC, Lau L, Kongkham PN, Wu X, Garzia L, Roberts SS, Massimi L, Meter TV, ... Weiss WA, et al. Abstract 1428: A CpG island methylator phenotype defines a clinically aggressive subgroup of posterior fossa ependymoma Cancer Research. 72: 1428-1428. DOI: 10.1158/1538-7445.Am2012-1428 |
0.348 |
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| 2012 |
Petritsch C, Sugiarto S, Persson A, Weiss WA. Abstract 1016: Asymmetry-defective oligodendrocyte progenitors are glioma precursors Cancer Research. 72: 1016-1016. DOI: 10.1158/1538-7445.Am2012-1016 |
0.588 |
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| 2012 |
Dasgupta T, Yang X, Hashizume R, Olow A, Kolkowitz I, Weiss W, Mueller S, Nicolaides T, James C, Haas-Kogan D. Survival Advantage With Radiation Combined With a Selective BRAFV600E Inhibitor in an Orthotopic, Intracranial Model of BRAFV600E-mutated High-grade Gliomas International Journal of Radiation Oncology*Biology*Physics. 84: S125. DOI: 10.1016/J.Ijrobp.2012.07.125 |
0.605 |
|
| 2011 |
Bhargava S, Mueller S, Wehmeijer L, Yang X, Gragg A, Matthay KK, Weiss WA, Haas-Kogan DA. PARP-1 inhibitor MK-4827 in combination with radiation as a treatment strategy for metastatic neuroblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 9559. PMID 28019766 DOI: 10.1200/Jco.2011.29.15_Suppl.9559 |
0.382 |
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| 2011 |
Nicolaides TP, Li H, Solomon DA, Hariono S, Hashizume R, Barkovich K, Baker SJ, Paugh BS, Jones C, Forshew T, Hindley GF, Hodgson JG, Kim JS, Rowitch DH, Weiss WA, et al. Targeted therapy for BRAFV600E malignant astrocytoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7595-604. PMID 22038996 DOI: 10.1158/1078-0432.Ccr-11-1456 |
0.69 |
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| 2011 |
Chesler L, Weiss WA. Genetically engineered murine models--contribution to our understanding of the genetics, molecular pathology and therapeutic targeting of neuroblastoma. Seminars in Cancer Biology. 21: 245-55. PMID 21958944 DOI: 10.1016/J.Semcancer.2011.09.011 |
0.604 |
|
| 2011 |
Sugiarto S, Persson AI, Munoz EG, Waldhuber M, Lamagna C, Andor N, Hanecker P, Ayers-Ringler J, Phillips J, Siu J, Lim DA, Vandenberg S, Stallcup W, Berger MS, Bergers G, ... Weiss WA, et al. Asymmetry-defective oligodendrocyte progenitors are glioma precursors. Cancer Cell. 20: 328-40. PMID 21907924 DOI: 10.1016/J.Ccr.2011.08.011 |
0.574 |
|
| 2011 |
Witt H, Mack SC, Ryzhova M, Bender S, Sill M, Isserlin R, Benner A, Hielscher T, Milde T, Remke M, Jones DT, Northcott PA, Garzia L, Bertrand KC, Wittmann A, ... ... Weiss WA, et al. Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell. 20: 143-57. PMID 21840481 DOI: 10.1016/J.Ccr.2011.07.007 |
0.333 |
|
| 2011 |
Bertrand KC, Mack SC, Northcott PA, Garzia L, Dubuc A, Pfister SM, Rutka JT, Weiss WA, Taylor MD. PCDH10 is a candidate tumour suppressor gene in medulloblastoma. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. 27: 1243-9. PMID 21597995 DOI: 10.1007/S00381-011-1486-X |
0.363 |
|
| 2011 |
Mueller S, Yang X, Sottero TL, Gragg A, Prasad G, Polley MY, Weiss WA, Matthay KK, Davidoff AM, DuBois SG, Haas-Kogan DA. Cooperation of the HDAC inhibitor vorinostat and radiation in metastatic neuroblastoma: efficacy and underlying mechanisms. Cancer Letters. 306: 223-9. PMID 21497989 DOI: 10.1016/J.Canlet.2011.03.010 |
0.348 |
|
| 2011 |
More SS, Itsara M, Yang X, Geier EG, Tadano MK, Seo Y, Vanbrocklin HF, Weiss WA, Mueller S, Haas-Kogan DA, Dubois SG, Matthay KK, Giacomini KM. Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2339-49. PMID 21421857 DOI: 10.1158/1078-0432.Ccr-10-2949 |
0.371 |
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| 2011 |
Amaravadi RK, Lippincott-Schwartz J, Yin XM, Weiss WA, Takebe N, Timmer W, DiPaola RS, Lotze MT, White E. Principles and current strategies for targeting autophagy for cancer treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 654-66. PMID 21325294 DOI: 10.1158/1078-0432.Ccr-10-2634 |
0.388 |
|
| 2011 |
Prasad G, Sottero T, Yang X, Mueller S, James CD, Weiss WA, Polley MY, Ozawa T, Berger MS, Aftab DT, Prados MD, Haas-Kogan DA. Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide. Neuro-Oncology. 13: 384-92. PMID 21317208 DOI: 10.1093/Neuonc/Noq193 |
0.445 |
|
| 2011 |
Fan QW, Weiss WA. Autophagy and Akt promote survival in glioma. Autophagy. 7: 536-8. PMID 21266843 DOI: 10.4161/Auto.7.5.14779 |
0.399 |
|
| 2011 |
Miroshnikova YA, Acerbi I, Persson A, Paszek MJ, Weiss WA, Weaver VM. Abstract LB-96: Extrinsic and intrinsic force and GBM aggression Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-96 |
0.622 |
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| 2011 |
Swartling FJ, Persson AI, Lau J, Northcott PA, Grimmer MR, Chesler L, Perry A, Phillips JJ, Taylor MD, Weiss WA. Abstract 3451: Interactions between N-myc and Sox9 promote medulloblastoma and determine cell fate decisions in cerebellar neural stem cells Cancer Research. 71: 3451-3451. DOI: 10.1158/1538-7445.Am2011-3451 |
0.821 |
|
| 2011 |
Barkovich KJ, Nicolaides T, Hariono S, Garske A, Fan QW, Shokat K, Weiss WA. Abstract 2314: Erlotinib response in lung- and glioma-derived EGFR alleles: Correlating kinase site occupancy with efficacy Cancer Research. 71: 2314-2314. DOI: 10.1158/1538-7445.Am2011-2314 |
0.695 |
|
| 2011 |
Chanthery YH, Gustafson WC, Weiss WA. Abstract 1558: Paracrine signaling through Mycn enhances tumor-vascular microenvironment in neuroblastoma Cancer Research. 71: 1558-1558. DOI: 10.1158/1538-7445.Am2011-1558 |
0.834 |
|
| 2011 |
Pavel H, Ajeawung N, Faure R, Poirier D, Kamnasaran D, Ajeawung N, Joshi H, Kamnasaran D, Poirier D, Ajeawung N, Kamnasaran D, Lun X, Zemp F, Sun B, Stechishin O, ... ... Weiss W, et al. PRECLINICAL EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 13: iii107-iii120. DOI: 10.1093/Neuonc/Nor158 |
0.609 |
|
| 2010 |
Gustafson WC, Weiss WA. Addiction to B-MYB. Oncotarget. 1: 235-6. PMID 21304174 DOI: 10.18632/oncotarget.100807 |
0.583 |
|
| 2010 |
Persson AI, Petritsch C, Swartling FJ, Itsara M, Sim FJ, Auvergne R, Goldenberg DD, Vandenberg SR, Nguyen KN, Yakovenko S, Ayers-Ringler J, Nishiyama A, Stallcup WB, Berger MS, Bergers G, ... ... Weiss WA, et al. Non-stem cell origin for oligodendroglioma. Cancer Cell. 18: 669-82. PMID 21156288 DOI: 10.1016/J.Ccr.2010.10.033 |
0.766 |
|
| 2010 |
Fan QW, Cheng C, Hackett C, Feldman M, Houseman BT, Nicolaides T, Haas-Kogan D, James CD, Oakes SA, Debnath J, Shokat KM, Weiss WA. Akt and autophagy cooperate to promote survival of drug-resistant glioma. Science Signaling. 3: ra81. PMID 21062993 DOI: 10.1126/Scisignal.2001017 |
0.815 |
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| 2010 |
Swarbrick A, Woods SL, Shaw A, Balakrishnan A, Phua Y, Nguyen A, Chanthery Y, Lim L, Ashton LJ, Judson RL, Huskey N, Blelloch R, Haber M, Norris MD, Lengyel P, ... ... Weiss W, et al. miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. Nature Medicine. 16: 1134-40. PMID 20871609 DOI: 10.1038/Nm.2227 |
0.8 |
|
| 2010 |
Fan QW, Weiss WA. Targeting the RTK-PI3K-mTOR axis in malignant glioma: overcoming resistance. Current Topics in Microbiology and Immunology. 347: 279-96. PMID 20535652 DOI: 10.1007/82_2010_67 |
0.474 |
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| 2010 |
Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, ... ... Weiss WA, et al. Pleiotropic role for MYCN in medulloblastoma. Genes & Development. 24: 1059-72. PMID 20478998 DOI: 10.1101/Gad.1907510 |
0.822 |
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| 2010 |
Yoon DJ, Kwan BH, Chao FC, Nicolaides TP, Phillips JJ, Lam GY, Mason AB, Weiss WA, Kamei DT. Intratumoral therapy of glioblastoma multiforme using genetically engineered transferrin for drug delivery. Cancer Research. 70: 4520-7. PMID 20460527 DOI: 10.1158/0008-5472.Can-09-4311 |
0.652 |
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| 2010 |
Gustafson WC, Weiss WA. Myc proteins as therapeutic targets. Oncogene. 29: 1249-59. PMID 20101214 DOI: 10.1038/Onc.2009.512 |
0.731 |
|
| 2010 |
Gustafson WC, Weiss WA. Addiction to B-MYB Oncotarget. 1: 235-236. DOI: 10.18632/Oncotarget.132 |
0.705 |
|
| 2010 |
Wu X, Collier L, Northcott P, Dubuc A, Eberhart C, Meter TV, Zagzag D, Croul S, Dupuy A, Scheetz TE, Scherer S, Bouffet E, Weiss WA, Largaespada DAD, Taylor MD. Abstract 4350: Clonal selection and parallel evolution during leptomeningeal dissemination of human and mouse medulloblastoma result in bicompartmental disease Cancer Research. 70: 4350-4350. DOI: 10.1158/1538-7445.Am10-4350 |
0.416 |
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| 2010 |
Nicolaides TP, Barkovich K, Hariono S, Garske A, Fan QW, Shokat K, Weiss WA. Abstract 1973: Targeting activated alleles of EGFR derived from glioma and lung cancer: Correlating kinase active-site occupancy with efficacy Cancer Research. 70: 1973-1973. DOI: 10.1158/1538-7445.Am10-1973 |
0.707 |
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| 2009 |
Hackett CS, Weiss WA. A translational end-run for a rare, genetically enigmatic tumor. Cancer Biology & Therapy. 8: 2396-7. PMID 20009571 DOI: 10.4161/Cbt.8.24.10507 |
0.73 |
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| 2009 |
Collier LS, Adams DJ, Hackett CS, Bendzick LE, Akagi K, Davies MN, Diers MD, Rodriguez FJ, Bender AM, Tieu C, Matise I, Dupuy AJ, Copeland NG, Jenkins NA, Hodgson JG, ... Weiss WA, et al. Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality. Cancer Research. 69: 8429-37. PMID 19843846 DOI: 10.1158/0008-5472.Can-09-1760 |
0.752 |
|
| 2009 |
Swartling FJ, Ferletta M, Kastemar M, Weiss WA, Westermark B. Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene. 28: 3121-3131. PMID 19543319 DOI: 10.1038/Onc.2009.168 |
0.725 |
|
| 2009 |
Persson AI, Weiss WA. The side story of stem-like glioma cells. Cell Stem Cell. 4: 191-2. PMID 19265652 DOI: 10.1016/J.Stem.2009.02.004 |
0.537 |
|
| 2009 |
Van Maerken T, Sarkar D, Speleman F, Dent P, Weiss WA, Fisher PB. Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma. Journal of Cellular Physiology. 219: 707-15. PMID 19202553 DOI: 10.1002/Jcp.21719 |
0.421 |
|
| 2009 |
Fan QW, Cheng C, Knight ZA, Haas-Kogan D, Stokoe D, James CD, McCormick F, Shokat KM, Weiss WA. EGFR signals to mTOR through PKC and independently of Akt in glioma. Science Signaling. 2: ra4. PMID 19176518 DOI: 10.1126/Scisignal.2000014 |
0.57 |
|
| 2009 |
Cheng CK, Fan QW, Weiss WA. PI3K signaling in glioma--animal models and therapeutic challenges. Brain Pathology (Zurich, Switzerland). 19: 112-20. PMID 19076776 DOI: 10.1111/J.1750-3639.2008.00233.X |
0.466 |
|
| 2009 |
Fan QW, Cheng C, Knight ZA, Haas-Kogan D, Stokoe D, James CD, McCormick F, Shokat KM, Weiss WA. Erratum: EGFR signals to mTOR through PKC and independently of Akt in glioma (Science Signaling (2009) 2:60 (er4)) Science Signaling. 2. DOI: 10.1126/Scisignal.260Er4 |
0.493 |
|
| 2008 |
Chesler L, Goldenberg DD, Collins R, Grimmer M, Kim GE, Tihan T, Nguyen K, Yakovenko S, Matthay KK, Weiss WA. Chemotherapy-induced apoptosis in a transgenic model of neuroblastoma proceeds through p53 induction. Neoplasia (New York, N.Y.). 10: 1268-74. PMID 18953436 DOI: 10.1593/Neo.08778 |
0.81 |
|
| 2008 |
Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. Bmc Medicine. 6: 14. PMID 18577219 DOI: 10.1186/1741-7015-6-14 |
0.612 |
|
| 2008 |
Torbett NE, Luna-Moran A, Knight ZA, Houk A, Moasser M, Weiss W, Shokat KM, Stokoe D. A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition. The Biochemical Journal. 415: 97-110. PMID 18498248 DOI: 10.1042/Bj20080639 |
0.591 |
|
| 2008 |
Chen JS, Zhou LJ, Entin-Meer M, Yang X, Donker M, Knight ZA, Weiss W, Shokat KM, Haas-Kogan D, Stokoe D. Characterization of structurally distinct, isoform-selective phosphoinositide 3'-kinase inhibitors in combination with radiation in the treatment of glioblastoma. Molecular Cancer Therapeutics. 7: 841-50. PMID 18413797 DOI: 10.1158/1535-7163.Mct-07-0393 |
0.574 |
|
| 2008 |
Grimmer MR, Weiss WA. BMPs oppose Math1 in cerebellar development and in medulloblastoma. Genes & Development. 22: 693-9. PMID 18347086 DOI: 10.1101/Gad.1657808 |
0.758 |
|
| 2007 |
Weiss WA, Taylor SS, Shokat KM. Recognizing and exploiting differences between RNAi and small-molecule inhibitors. Nature Chemical Biology. 3: 739-44. PMID 18007642 DOI: 10.1038/Nchembio1207-739 |
0.464 |
|
| 2007 |
Chesler L, Goldenberg DD, Seales IT, Satchi-Fainaro R, Grimmer M, Collins R, Struett C, Nguyen KN, Kim G, Tihan T, Bao Y, Brekken RA, Bergers G, Folkman J, Weiss WA. Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma. Cancer Research. 67: 9435-42. PMID 17909053 DOI: 10.1158/0008-5472.Can-07-1316 |
0.818 |
|
| 2007 |
Fan QW, Cheng CK, Nicolaides TP, Hackett CS, Knight ZA, Shokat KM, Weiss WA. A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma. Cancer Research. 67: 7960-5. PMID 17804702 DOI: 10.1158/0008-5472.Can-07-2154 |
0.806 |
|
| 2007 |
Meyer GE, Chesler L, Liu D, Gable K, Maddux BA, Goldenberg DD, Youngren JF, Goldfine ID, Weiss WA, Matthay KK, Rosenthal SM. Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells. Journal of Cellular Biochemistry. 102: 1529-41. PMID 17486636 DOI: 10.1002/Jcb.21373 |
0.637 |
|
| 2007 |
Cheng AJ, Cheng NC, Ford J, Smith J, Murray JE, Flemming C, Lastowska M, Jackson MS, Hackett CS, Weiss WA, Marshall GM, Kees UR, Norris MD, Haber M. Cell lines from MYCN transgenic murine tumours reflect the molecular and biological characteristics of human neuroblastoma. European Journal of Cancer (Oxford, England : 1990). 43: 1467-75. PMID 17449239 DOI: 10.1016/J.Ejca.2007.03.008 |
0.732 |
|
| 2007 |
Blair JA, Rauh D, Kung C, Yun CH, Fan QW, Rode H, Zhang C, Eck MJ, Weiss WA, Shokat KM. Structure-guided development of affinity probes for tyrosine kinases using chemical genetics. Nature Chemical Biology. 3: 229-38. PMID 17334377 DOI: 10.1038/Nchembio866 |
0.542 |
|
| 2006 |
Ohgaki H, Kita D, Favereaux A, Huang H, Homma T, Dessen P, Weiss WA, Kleihues P, Heppner FL. Brain tumors in S100beta-v-erbB transgenic rats. Journal of Neuropathology and Experimental Neurology. 65: 1111-7. PMID 17146284 DOI: 10.1097/01.Jnen.0000248544.28423.48 |
0.402 |
|
| 2006 |
Fan QW, Weiss WA. Isoform specific inhibitors of PI3 kinase in glioma. Cell Cycle (Georgetown, Tex.). 5: 2301-5. PMID 17102612 DOI: 10.4161/Cc.5.20.3362 |
0.448 |
|
| 2006 |
Grimmer MR, Weiss WA. Childhood tumors of the nervous system as disorders of normal development. Current Opinion in Pediatrics. 18: 634-8. PMID 17099362 DOI: 10.1097/Mop.0B013E32801080Fe |
0.749 |
|
| 2006 |
Chesler L, Schlieve C, Goldenberg DD, Kenney A, Kim G, McMillan A, Matthay KK, Rowitch D, Weiss WA. Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma Cancer Research. 66: 8139-8146. PMID 16912192 DOI: 10.1158/0008-5472.Can-05-2769 |
0.682 |
|
| 2006 |
Fan QW, Knight ZA, Goldenberg DD, Yu W, Mostov KE, Stokoe D, Shokat KM, Weiss WA. A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell. 9: 341-9. PMID 16697955 DOI: 10.1016/J.Ccr.2006.03.029 |
0.579 |
|
| 2006 |
Knight ZA, Gonzalez B, Feldman ME, Zunder ER, Goldenberg DD, Williams O, Loewith R, Stokoe D, Balla A, Toth B, Balla T, Weiss WA, Williams RL, Shokat KM. A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 125: 733-47. PMID 16647110 DOI: 10.1016/J.Cell.2006.03.035 |
0.496 |
|
| 2006 |
Fan QW, Weiss WA. Chemical genetic approaches to the development of cancer therapeutics. Current Opinion in Genetics & Development. 16: 85-91. PMID 16359858 DOI: 10.1016/J.Gde.2005.12.002 |
0.402 |
|
| 2005 |
Hong C, Maunakea A, Jun P, Bollen AW, Hodgson JG, Goldenberg DD, Weiss WA, Costello JF. Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8. Cancer Research. 65: 3617-23. PMID 15867356 DOI: 10.1158/0008-5472.Can-05-0048 |
0.456 |
|
| 2005 |
Fan QW, Weiss WA. RNA interference against a glioma-derived allele of EGFR induces blockade at G2M. Oncogene. 24: 829-37. PMID 15580296 DOI: 10.1038/Sj.Onc.1208227 |
0.435 |
|
| 2005 |
Stauffer JK, Greer B, Lincoln E, Back TC, Hixon JA, Whiteford C, Eisenhofer G, Tsokos M, Weiss W, Khan J, Wigginton JM. High-Throughput Molecular and Histopathologic Profiling of the Tumor Microenvironment in A Novel Transplantable Model of Murine Neuroblastoma: New Tools for Pediatric Drug Discovery Journal of Immunotherapy. 28: 638-639. DOI: 10.1097/01.Cji.0000191032.15201.C1 |
0.353 |
|
| 2004 |
Hansford LM, Thomas WD, Keating JM, Burkhart CA, Peaston AE, Norris MD, Haber M, Armati PJ, Weiss WA, Marshall GM. Mechanisms of embryonal tumor initiation: distinct roles for MycN expression and MYCN amplification. Proceedings of the National Academy of Sciences of the United States of America. 101: 12664-9. PMID 15314226 DOI: 10.1073/Pnas.0401083101 |
0.396 |
|
| 2004 |
Weiss WA, Banerjee A. Can mouse models for brain tumors inform treatment in pediatric patients? Seminars in Cancer Biology. 14: 71-7. PMID 14757537 DOI: 10.1016/J.Semcancer.2003.11.008 |
0.426 |
|
| 2003 |
Fan QW, Specht KM, Zhang C, Goldenberg DD, Shokat KM, Weiss WA. Combinatorial efficacy achieved through two-point blockade within a signaling pathway-a chemical genetic approach. Cancer Research. 63: 8930-8. PMID 14695210 |
0.557 |
|
| 2003 |
Hackett CS, Hodgson JG, Law ME, Fridlyand J, Osoegawa K, de Jong PJ, Nowak NJ, Pinkel D, Albertson DG, Jain A, Jenkins R, Gray JW, Weiss WA. Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors. Cancer Research. 63: 5266-73. PMID 14500357 |
0.736 |
|
| 2003 |
Burkhart CA, Cheng AJ, Madafiglio J, Kavallaris M, Mili M, Marshall GM, Weiss WA, Khachigian LM, Norris MD, Haber M. Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma. Journal of the National Cancer Institute. 95: 1394-403. PMID 13130115 DOI: 10.1093/Jnci/Djg045 |
0.35 |
|
| 2003 |
Yip S, Aboody KS, Burns M, Imitola J, Boockvar JA, Allport J, Park KI, Teng YD, Lachyankar M, McIntosh T, O'Rourke DM, Khoury S, Weissleder R, Black PM, Weiss W, et al. Neural stem cell biology may be well suited for improving brain tumor therapies. Cancer Journal (Sudbury, Mass.). 9: 189-204. PMID 12952304 DOI: 10.1097/00130404-200305000-00007 |
0.431 |
|
| 2003 |
Gutmann DH, Baker SJ, Giovannini M, Garbow J, Weiss W. Mouse models of human cancer consortium symposium on nervous system tumors. Cancer Research. 63: 3001-4. PMID 12782610 |
0.32 |
|
| 2003 |
Weiss WA, Burns MJ, Hackett C, Aldape K, Hill JR, Kuriyama H, Kuriyama N, Milshteyn N, Roberts T, Wendland MF, DePinho R, Israel MA. Genetic determinants of malignancy in a mouse model for oligodendroglioma. Cancer Research. 63: 1589-95. PMID 12670909 |
0.759 |
|
| 2003 |
Burns MJ, Weiss W. Targeted therapy of brain tumors utilizing neural stem and progenitor cells. Frontiers in Bioscience : a Journal and Virtual Library. 8: e228-34. PMID 12456351 DOI: 10.2741/953 |
0.369 |
|
| 2002 |
Weiss WA, Israel M, Cobbs C, Holland E, James CD, Louis DN, Marks C, McClatchey AI, Roberts T, Van Dyke T, Wetmore C, Chiu IM, Giovannini M, Guha A, Higgins RJ, et al. Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum. Oncogene. 21: 7453-63. PMID 12386807 DOI: 10.1038/Sj.Onc.1205936 |
0.435 |
|
| 2002 |
Fan QW, Zhang C, Shokat KM, Weiss WA. Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling. Current Biology : Cb. 12: 1386-94. PMID 12194819 DOI: 10.1016/S0960-9822(02)01070-9 |
0.565 |
|
| 2002 |
Tada T, Wendland M, Watson N, Kuriyama N, Kuriyama H, Roberts T, Burns M, Weiss W, Israel MA. A head holder for magnetic resonance imaging that allows the stereotaxic alignment of spontaneously occurring intracranial mouse tumors. Journal of Neuroscience Methods. 116: 1-7. PMID 12007978 DOI: 10.1016/S0165-0270(02)00014-6 |
0.36 |
|
| 2002 |
Weiss WA, Chesler L. Tumor Models in Cancer Research Drug Discovery Today. 7: 997. DOI: 10.1016/S1359-6446(02)02399-1 |
0.624 |
|
| 2000 |
Norris MD, Burkhart CA, Marshall GM, Weiss WA, Haber M. Expression of N-myc and MRP genes and their relationship to N-myc gene dosage and tumor formation in a murine neuroblastoma model. Medical and Pediatric Oncology. 35: 585-9. PMID 11107123 DOI: 10.1002/1096-911X(20001201)35:6<585::Aid-Mpo20>3.0.Co;2-P |
0.362 |
|
| 2000 |
Weiss WA. Genetics of brain tumors. Current Opinion in Pediatrics. 12: 543-548. PMID 11106272 DOI: 10.1097/00008480-200012000-00005 |
0.376 |
|
| 1999 |
Weiss WA, Brown PO, Francisco C, Godfrey T, Milshteyn N, Pollack J, Wade J, Yee G, Zhu J, Bishop JM. MYCN and Neuroblastoma in Transgenic Mice Pediatric Research. 45: 154-154. DOI: 10.1203/00006450-199904020-00914 |
0.546 |
|
| 1997 |
Weiss WA, Aldape K, Mohapatra G, Feuerstein BG, Bishop JM. Targeted expression of MYCN causes neuroblastoma in transgenic mice. The Embo Journal. 16: 2985-95. PMID 9214616 DOI: 10.1093/Emboj/16.11.2985 |
0.569 |
|
| 1990 |
Bardwell L, Burtscher H, Weiss WA, Nicolet CM, Friedberg EC. Characterization of the RAD10 gene of Saccharomyces cerevisiae and purification of Rad10 protein Biochemistry. 29: 3119-3126. PMID 2110825 DOI: 10.1021/Bi00464A031 |
0.482 |
|
| 1988 |
Lambert C, Couto LB, Weiss WA, Schultz RA, Thompson LH, Friedberg EC. A yeast DNA repair gene partially complements defective excision repair in mammalian cells. The Embo Journal. 7: 3245-3253. DOI: 10.1002/J.1460-2075.1988.Tb03191.X |
0.506 |
|
| 1987 |
Weiss WA, Edelman I, Culbertson MR, Friedberg EC. Physiological levels of normal tRNA(CAGGln) can effect partial suppression of amber mutations in the yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 84: 8031-4. PMID 3120182 DOI: 10.1073/Pnas.84.22.8031 |
0.507 |
|
| 1987 |
Friedberg EC, Weiss WA. Divergent genetic codes Nature. 325: 306-306. PMID 3100958 DOI: 10.1038/325306A0 |
0.447 |
|
| 1986 |
Friedberg EC, Barbis DP, Chenevert JM, Fleer R, Kalainov D, Naumovski L, Nicolet CM, Robinson GW, Schultz RA, Weiss WA. Molecular Approaches to the Study of Nucleotide Excision Repair in Eukaryotes Basic Life Sciences. 38: 311-318. PMID 3527144 DOI: 10.1007/978-1-4615-9462-8_33 |
0.513 |
|
| 1986 |
Weiss WA, Friedberg EC. Normal yeast tRNACAGGln can suppress amber codons and is encoded by an essential gene Journal of Molecular Biology. 192: 725-735. PMID 3295253 DOI: 10.1016/0022-2836(86)90024-0 |
0.482 |
|
| 1986 |
Friedberg EC, Fleer R, Naumovski L, Nicolet CM, Robinson GW, Weiss WA, Yang E. Nucleotide Excision Repair Genes from the Yeast Saccharomyces Cerevisiae Basic Life Sciences. 39: 231-242. PMID 3094493 DOI: 10.1007/978-1-4684-5182-5_20 |
0.491 |
|
| 1985 |
Weiss WA, Friedberg EC. Molecular cloning and characterization of the yeast RAD10 gene and expression of RAD10 protein in E. coli. The Embo Journal. 4: 1575-1582. DOI: 10.1002/J.1460-2075.1985.Tb03819.X |
0.486 |
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