David S. Latchman, Ph.D. - Publications

Affiliations: 
Molecular Pathology University College London, London, United Kingdom 
Area:
Gene Regulation

259 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Hudson CD, Morris PJ, Latchman DS, Budhram-Mahadeo VS. Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate. The Journal of Biological Chemistry. 291: 15909. PMID 27451431 DOI: 10.1074/Jbc.A116.408679  0.365
2013 Carroll CJ, Sayan BS, Bailey SG, McCormick J, Stephanou A, Latchman DS, Townsend PA. Regulation of myocardial interleukin-6 expression by p53 and STAT1. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 542-8. PMID 23675777 DOI: 10.1089/Jir.2012.0165  0.309
2012 McCormick J, Knight RA, Barry SP, Scarabelli TM, Abounit K, Latchman DS, Stephanou A. Autophagy in the stress-induced myocardium. Frontiers in Bioscience (Elite Edition). 4: 2131-2141. PMID 22202025 DOI: 10.2741/530  0.322
2012 Latchman DS. HSV-Cellular Protein Interactions. Methods in Molecular Medicine. 10: 257-72. PMID 21374235 DOI: 10.1385/0-89603-347-3:257  0.388
2010 Dimco G, Knight RA, Latchman DS, Stephanou A. STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest Cell Cycle. 9: 4638-4649. PMID 21084836 DOI: 10.4161/Cc.9.23.13955  0.31
2010 Barry SP, Lawrence KM, McCormick J, Soond SM, Hubank M, Eaton S, Sivarajah A, Scarabelli TM, Knight RA, Thiemermann C, Latchman DS, Townsend PA, Stephanou A. New targets of urocortin-mediated cardioprotection Journal of Molecular Endocrinology. 45: 69-85. PMID 20501665 DOI: 10.1677/Jme-09-0148  0.369
2010 Gascoyne DM, Dunne J, Behjati S, Sebire NJ, Anderson J, Latchman DS. EWS/ETS proteins promote expression and regulate function of the homeodomain transcription factor BRN3A Oncogene. 29: 3134-3145. PMID 20348952 DOI: 10.1038/Onc.2010.72  0.367
2010 Ripley BJM, Fujimoto M, Serada S, Ohkawara T, Nishikawa T, Terabe F, Matsukawa Y, Stephanou A, Knight RA, Isenberg DA, Latchman DS, Kishimoto T, Naka T. Green tea polyphenol epigallocatechin gallate inhibits cell signaling by inducing SOCS1 gene expression International Immunology. 22: 359-366. PMID 20190037 DOI: 10.1093/Intimm/Dxq015  0.342
2010 van der Weerd L, Tariq Akbar M, Aron Badin R, Valentim LM, Thomas DL, Wells DJ, Latchman DS, Gadian DG, Lythgoe MF, de Belleroche JS. Overexpression of heat shock protein 27 reduces cortical damage after cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 849-56. PMID 19997117 DOI: 10.1038/Jcbfm.2009.249  0.322
2009 Barry SP, Townsend PA, McCormick J, Knight RA, Scarabelli TM, Latchman DS, Stephanou A. STAT3 deletion sensitizes cells to oxidative stress Biochemical and Biophysical Research Communications. 385: 324-329. PMID 19450559 DOI: 10.1016/J.Bbrc.2009.05.051  0.338
2009 Giles I, Pericleous C, Liu X, Ehsanullah J, Clarke L, Brogan P, Newton-West M, Swerlick R, Lambrianides A, Chen P, Latchman D, Isenberg D, Pierangeli S, Rahman A. Thrombin binding predicts the effects of sequence changes in a human monoclonal antiphospholipid antibody on its in vivo biologic actions Journal of Immunology. 182: 4836-4843. PMID 19342662 DOI: 10.4049/Jimmunol.0804241  0.307
2009 Berwick DC, Calissano M, Corness JD, Cook SJ, Latchman DS. Regulation of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation. Brain Research. 1256: 8-18. PMID 19135033 DOI: 10.1016/J.Brainres.2008.12.009  0.338
2009 Scarabelli TM, Mariotto S, Abdel-Azeim S, Shoji K, Darra E, Stephanou A, Chen-Scarabelli C, Marechal JD, Knight R, Ciampa A, Saravolatz L, de Prati AC, Yuan Z, Cavalieri E, Menegazzi M, ... Latchman D, et al. Targeting STAT1 by myricetin and delphinidin provides efficient protection of the heart from ischemia/reperfusion-induced injury Febs Letters. 583: 531-541. PMID 19116149 DOI: 10.1016/J.Febslet.2008.12.037  0.308
2008 Scarabelli TM, Townsend PA, Chen Scarabelli C, Yuan Z, McCauley RB, Di Rezze J, Patel D, Putt J, Allebban Z, Abboud J, Chilukuri K, Gardin J, Saravolatz L, Knight RA, Latchman DS, et al. Amino acid supplementation differentially modulates STAT1 and STAT3 activation in the myocardium exposed to ischemia/reperfusion injury. The American Journal of Cardiology. 101: 63E-68E. PMID 18514629 DOI: 10.1016/J.Amjcard.2008.03.003  0.309
2008 Soond SM, Barry SP, Melino G, Knight RA, Latchman DS, Stephanou A. p73-mediated transcriptional activity is negatively regulated by polo-like kinase Cell Cycle. 7: 1214-1223. PMID 18418051 DOI: 10.4161/Cc.7.9.5777  0.371
2008 Soond SM, Townsend PA, Barry SP, Knight RA, Latchman DS, Stephanou A. ERK and the F-box protein βTRCP target STAT1 for degradation Journal of Biological Chemistry. 283: 16077-16083. PMID 18378670 DOI: 10.1074/Jbc.M800384200  0.34
2008 Farooqui-Kabir SR, Diss JKJ, Henderson D, Marber MS, Latchman DS, Budhram-Mahadeo V, Heads RJ. Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression Cell Stress and Chaperones. 13: 297-312. PMID 18368538 DOI: 10.1007/S12192-008-0028-2  0.365
2008 Sharp PS, Akbar MT, Bouri S, Senda A, Joshi K, Chen HJ, Latchman DS, Wells DJ, de Belleroche J. Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression Neurobiology of Disease. 30: 42-55. PMID 18255302 DOI: 10.1016/J.Nbd.2007.12.002  0.301
2008 Diss JK, Calissano M, Gascoyne D, Djamgoz MB, Latchman DS. Identification and characterization of the promoter region of the Nav1.7 voltage-gated sodium channel gene (SCN9A). Molecular and Cellular Neurosciences. 37: 537-47. PMID 18249135 DOI: 10.1016/J.Mcn.2007.12.002  0.338
2008 Budhram-Mahadeo VS, Irshad S, Bowen S, Lee SA, Samady L, Tonini GP, Latchman DS. Proliferation-associated Brn-3b transcription factor can activate cyclin D1 expression in neuroblastoma and breast cancer cells Oncogene. 27: 145-154. PMID 17637757 DOI: 10.1038/Sj.Onc.1210621  0.302
2007 Calissano M, Diss JKJ, Latchman DS. Post-transcriptional regulation of the Brn-3b transcription factor in differentiating neuroblastoma cells Febs Letters. 581: 2490-2496. PMID 17490655 DOI: 10.1016/J.Febslet.2007.04.066  0.359
2007 Zourlidou A, Gidalevitz T, Kristiansen M, Landles C, Woodman B, Wells DJ, Latchman DS, de Belleroche J, Tabrizi SJ, Morimoto RI, Bates GP. Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation. Human Molecular Genetics. 16: 1078-90. PMID 17360721 DOI: 10.1093/Hmg/Ddm057  0.317
2007 Soond SM, Carroll C, Townsend PA, Sayan E, Melino G, Behrmann I, Knight RA, Latchman DS, Stephanou A. STAT1 regulates p73-mediated Bax gene expression Febs Letters. 581: 1217-1226. PMID 17346710 DOI: 10.1016/J.Febslet.2007.02.049  0.328
2007 Francis YI, Diss JKJ, Kariti M, Stephanou A, Latchman DS. p300 activation by Presenilin 1 but not by its M146L mutant Neuroscience Letters. 413: 137-140. PMID 17197080 DOI: 10.1016/J.Neulet.2006.11.036  0.308
2006 Budhram-Mahadeo VS, Bowen S, Lee S, Perez-Sanchez C, Ensor E, Morris PJ, Latchman DS. Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression Nucleic Acids Research. 34: 6640-6652. PMID 17145718 DOI: 10.1093/Nar/Gkl878  0.349
2006 McCormick J, Barry SP, Sivarajah A, Stefanutti G, Townsend PA, Lawrence KM, Eaton S, Knight RA, Thiemermann C, Latchman DS, Stephanou A. Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2115-7. PMID 16935931 DOI: 10.1096/Fj.06-6188Fje  0.317
2006 Soond SM, Latchman DS, Stephanou A. STAT signalling in the heart and cardioprotection Expert Reviews in Molecular Medicine. 8: 1-16. PMID 16836797 DOI: 10.1017/S1462399406000032  0.312
2006 Francis YI, Stephanou A, Latchman DS. CREB-binding protein activation by presenilin 1 but not by its M146L mutant Neuroreport. 17: 917-921. PMID 16738488 DOI: 10.1097/01.Wnr.0000220137.06542.A0  0.36
2006 Valentim L, Laurence KM, Townsend PA, Carroll CJ, Soond S, Scarabelli TM, Knight RA, Latchman DS, Stephanou A. Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury Journal of Molecular and Cellular Cardiology. 40: 846-852. PMID 16697404 DOI: 10.1016/J.Yjmcc.2006.03.428  0.32
2006 Kabakov AE, Malyutina YV, Latchman DS. Hsf1-mediated stress response can transiently enhance cellular radioresistance Radiation Research. 165: 410-423. PMID 16579653 DOI: 10.1667/Rr3514.1  0.352
2006 Scarabelli TM, Knight R, Stephanou A, Townsend P, Chen-Scarabelli C, Lawrence K, Gottlieb R, Latchman D, Narula J. Clinical implications of apoptosis in ischemic myocardium Current Problems in Cardiology. 31: 181-264. PMID 16503249 DOI: 10.1016/J.Cpcardiol.2005.11.002  0.314
2006 Diss JK, Faulkes DJ, Walker MM, Patel A, Foster CS, Budhram-Mahadeo V, Djamgoz MB, Latchman DS. Brn-3a neuronal transcription factor functional expression in human prostate cancer. Prostate Cancer and Prostatic Diseases. 9: 83-91. PMID 16276351 DOI: 10.1038/Sj.Pcan.4500837  0.363
2006 Samady L, Faulkes DJ, Budhram-Mahadeo V, Ndisang D, Potter E, Brabant G, Latchman DS. The Brn-3b POU family transcription factor represses plakoglobin gene expression in human breast cancer cells International Journal of Cancer. 118: 869-878. PMID 16152597 DOI: 10.1002/Ijc.21435  0.344
2006 Badin RA, Lythgoe MF, van der Weerd L, Thomas DL, Gadian DG, Latchman DS. Neuroprotective effects of virally delivered HSPs in experimental stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 371-81. PMID 16079790 DOI: 10.1038/Sj.Jcbfm.9600190  0.318
2005 Mason LJ, Lambrianides A, Haley JD, Manson JJ, Latchman DS, Isenberg DA, Rahman A. Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity. Arthritis Research & Therapy. 7: R971-83. PMID 16207338 DOI: 10.1186/Ar1768  0.302
2005 Calissano M, Faulkes D, Latchman DS. Phosphorylation of the Brn-3a transcription factor is modulated during differentiation and regulates its functional activity Molecular Brain Research. 141: 10-18. PMID 16126301 DOI: 10.1016/J.Molbrainres.2005.07.013  0.367
2005 Patel YJK, Payne Smith MD, De Belleroche J, Latchman DS. Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells Molecular Brain Research. 134: 256-274. PMID 15836922 DOI: 10.1016/J.Molbrainres.2004.10.028  0.338
2005 Lee SA, Ndisang D, Patel C, Dennis JH, Faulkes DJ, D'Arrigo C, Samady L, Farooqui-Kabir S, Heads RJ, Latchman DS, Budhram-Mahadeo VS. Expression of the Brn-3b transcription factor correlates with expression of HSP-27 in cancer and is required for maximal activation of the HSP-27 promoter Cancer Research. 65: 3072-3080. PMID 15833836 DOI: 10.1158/0008-5472.Can-04-2865  0.62
2005 Ripley BJM, Rahman MA, Isenberg DA, Latchman DS. Elevated expression of the Brn-3a and Brn-3b transcription factors in systemic lupus erythematosus correlates with antibodies to Brn-3 and overexpression of Hsp90 Arthritis and Rheumatism. 52: 1171-1179. PMID 15818685 DOI: 10.1002/Art.21000  0.37
2005 Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage Journal of Cell Science. 118: 1629-1639. PMID 15784679 DOI: 10.1242/Jcs.01728  0.316
2005 Davidson SM, Townsend PA, Carroll C, Yurek-George A, Balasubramanyam K, Kundu TK, Stephanou A, Packham G, Ganesan A, Latchman DS. The transcriptional coactivator p300 plays a critical role in the hypertrophic and protective pathways induced by phenylephrine in cardiac cells but is specific to the hypertrophic effect of urocortin Chembiochem. 6: 162-170. PMID 15593114 DOI: 10.1002/Cbic.200400246  0.331
2005 Townsend PA, Stephanou A, Packham G, Latchman DS. BAG-1: A multi-functional pro-survival molecule International Journal of Biochemistry and Cell Biology. 37: 251-259. PMID 15474970 DOI: 10.1016/J.Biocel.2004.03.016  0.348
2004 Kabakov AE, Budagova KR, Malyutina YV, Latchman DS, Csermely P. Pharmacological attenuation of apoptosis in reoxygenated endothelial cells. Cellular and Molecular Life Sciences : Cmls. 61: 3076-86. PMID 15583868 DOI: 10.1007/S00018-004-4204-Y  0.33
2004 Munarriz E, Barcaroli D, Stephanou A, Townsend PA, Maisse C, Terrinoni A, Neale MH, Martin SJ, Latchman DS, Knight RA, Melino G, De Laurenzi V. PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73. Molecular and Cellular Biology. 24: 10593-610. PMID 15572666 DOI: 10.1128/Mcb.24.24.10593-10610.2004  0.312
2004 MacCormac LP, Muqit MM, Faulkes DJ, Wood NW, Latchman DS. Reduction in endogenous parkin levels renders glial cells sensitive to both caspase-dependent and caspase-independent cell death. The European Journal of Neuroscience. 20: 2038-48. PMID 15450083 DOI: 10.1111/J.1460-9568.2004.03659.X  0.349
2004 Lawrence KM, Townsend PA, Davidson SM, Carroll CJ, Eaton S, Hubank M, Knight RA, Stephanou A, Latchman DS. The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage. Biochemical and Biophysical Research Communications. 321: 479-86. PMID 15358201 DOI: 10.1016/J.Bbrc.2004.06.170  0.328
2004 Townsend PA, Scarabelli TM, Pasini E, Gitti G, Menegazzi M, Suzuki H, Knight RA, Latchman DS, Stephanou A. Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1621-3. PMID 15319365 DOI: 10.1096/Fj.04-1716Fje  0.325
2004 West DA, Valentim LM, Lythgoe MF, Stephanou A, Proctor E, van der Weerd L, Ordidge RJ, Latchman DS, Gadian DG. MR image-guided investigation of regional signal transducers and activators of transcription-1 activation in a rat model of focal cerebral ischemia. Neuroscience. 127: 333-9. PMID 15262323 DOI: 10.1016/J.Neuroscience.2004.05.022  0.312
2004 Faulkes DJ, Ensor E, Le Rouzic E, Latchman DS. Distinct domains of Brn-3a regulate apoptosis and neurite outgrowth in vivo. Neuroreport. 15: 1421-5. PMID 15194866 DOI: 10.1097/01.Wnr.0000129371.81377.05  0.318
2004 Thomas GR, Faulkes DJ, Gascoyne D, Latchman DS. EWS differentially activates transcription of the Brn-3a long and short isoform mRNAs from distinct promoters Biochemical and Biophysical Research Communications. 318: 1045-1051. PMID 15147979 DOI: 10.1016/J.Bbrc.2004.04.134  0.357
2004 Parkinson EJ, Townsend PA, Stephanou A, Latchman DS, Eaton S, Pierro A. The Protective Effect of Moderate Hypothermia during Intestinal Ischemia-Reperfusion is Associated with Modification of Hepatic Transcription Factor Activation Journal of Pediatric Surgery. 39: 696-701. PMID 15137002 DOI: 10.1016/J.Jpedsurg.2004.01.025  0.314
2004 Calissano M, Ensor E, Brown DR, Latchman DS. Doppel expression is regulated by the Brn-3a and Brn-3b transcription factors. Neuroreport. 15: 483-6. PMID 15094508 DOI: 10.1097/00001756-200403010-00020  0.382
2004 Gascoyne DM, Thomas GR, Latchman DS. The effects of Brn-3a on neuronal differentiation and apoptosis are differentially modulated by EWS and its oncogenic derivative EWS/Fli-1. Oncogene. 23: 3830-40. PMID 15021903 DOI: 10.1038/Sj.Onc.1207497  0.372
2004 Alsbury S, Papageorgiou K, Latchman DS. Heat shock proteins can protect aged human and rodent cells from different stressful stimuli. Mechanisms of Ageing and Development. 125: 201-9. PMID 15013664 DOI: 10.1016/J.Mad.2003.11.015  0.321
2004 Zourlidou A, Payne Smith MD, Latchman DS. HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells. Journal of Neurochemistry. 88: 1439-48. PMID 15009645 DOI: 10.1046/J.1471-4159.2003.02273.X  0.334
2004 Gusterson RJ, Yuan LW, Latchman DS. Distinct serine residues in CBP and p300 are necessary for their activation by phenylephrine. The International Journal of Biochemistry & Cell Biology. 36: 893-9. PMID 15006641 DOI: 10.1016/J.Biocel.2003.10.004  0.327
2004 Townsend PA, Cutress RI, Carroll CJ, Lawrence KM, Scarabelli TM, Packham G, Stephanou A, Latchman DS. BAG-1 proteins protect cardiac myocytes from simulated ischemia/reperfusion-induced apoptosis via an alternate mechanism of cell survival independent of the proteasome. The Journal of Biological Chemistry. 279: 20723-8. PMID 14978028 DOI: 10.1074/Jbc.M400399200  0.365
2004 Samady L, Dennis J, Budhram-Mahadeo V, Latchman DS. Activation of CDK4 gene expression in human breast cancer cells by the Brn-3b POU family transcription factor. Cancer Biology & Therapy. 3: 317-23. PMID 14726699 DOI: 10.4161/Cbt.3.3.698  0.607
2004 Haley J, Mason LJ, Nagl S, Giles I, Latchman DS, Isenberg DA, Rahman A. Somatic mutations to arginine residues affect the binding of human monoclonal antibodies to DNA, histones, SmD and Ro antigen. Molecular Immunology. 40: 745-58. PMID 14687932 DOI: 10.1016/J.Molimm.2003.10.018  0.304
2004 Muqit MM, Davidson SM, Payne Smith MD, MacCormac LP, Kahns S, Jensen PH, Wood NW, Latchman DS. Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival. Human Molecular Genetics. 13: 117-35. PMID 14645198 DOI: 10.1093/Hmg/Ddh012  0.321
2004 Townsend PA, Scarabelli TM, Davidson SM, Knight RA, Latchman DS, Stephanou A. STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis. The Journal of Biological Chemistry. 279: 5811-20. PMID 14602726 DOI: 10.1074/Jbc.M302637200  0.349
2004 Irshad S, Pedley RB, Anderson J, Latchman DS, Budhram-Mahadeo VS. The Brn-3b transcription factor regulates the growth, behavior, and invasiveness of human neuroblastoma cells in vitro and in vivo Journal of Biological Chemistry. 279: 21617-21627. DOI: 10.1074/Jbc.A114.312506  0.324
2003 Kabakov AE, Budagova KR, Bryantsev AL, Latchman DS. Heat shock protein 70 or heat shock protein 27 overexpressed in human endothelial cells during posthypoxic reoxygenation can protect from delayed apoptosis. Cell Stress & Chaperones. 8: 335-47. PMID 15115286 DOI: 10.1379/1466-1268(2003)008<0335:Hspohs>2.0.Co;2  0.336
2003 Stephanou A, Latchman DS. STAT-1: a novel regulator of apoptosis. International Journal of Experimental Pathology. 84: 239-44. PMID 14748743 DOI: 10.1111/J.0959-9673.2003.00363.X  0.381
2003 Davidson SM, Stephanou A, Latchman DS. FLIP protects cardiomyocytes from apoptosis induced by simulated ischemia/reoxygenation, as demonstrated by short hairpin-induced (shRNA) silencing of FLIP mRNA. Journal of Molecular and Cellular Cardiology. 35: 1359-64. PMID 14596792 DOI: 10.1016/J.Yjmcc.2003.08.001  0.314
2003 Lawrence KM, Scarabelli TM, Turtle L, Chanalaris A, Townsend PA, Carroll CJ, Hubank M, Stephanou A, Knight RA, Latchman DS. Urocortin protects cardiac myocytes from ischemia/reperfusion injury by attenuating calcium-insensitive phospholipase A2 gene expression Faseb Journal. 17: 2313-2315. PMID 14563694 DOI: 10.1096/Fj.02-0832Fje  0.321
2003 Ensor E, Mathews K, Payne Smith MD, Latchman DS. Sensory neurons from mice lacking the Brn-3b POU family transcription factor are resistant to death-inducing stimuli both in vitro and in vivo. Brain Research. Molecular Brain Research. 117: 206-12. PMID 14559155 DOI: 10.1016/S0169-328X(03)00322-X  0.352
2003 Janjua S, Lawrence KM, Ng LL, Latchman DS. The cardioprotective agent urocortin induces expression of CT-1. Cardiovascular Toxicology. 3: 255-62. PMID 14555790 DOI: 10.1385/Ct:3:3:255  0.334
2003 Latchman DS. Herpes simplex virus vectors for Parkinson's disease. International Review of Neurobiology. 55: 223-41. PMID 12968539 DOI: 10.1016/S0074-7742(03)01010-9  0.331
2003 Calissano M, Latchman DS. Functional interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factor Oncogene. 22: 5408-5414. PMID 12934100 DOI: 10.1038/Sj.Onc.1206635  0.36
2003 Hargitai J, Lewis H, Boros I, Rácz T, Fiser A, Kurucz I, Benjamin I, Vígh L, Pénzes Z, Csermely P, Latchman DS. Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1 Biochemical and Biophysical Research Communications. 307: 689-695. PMID 12893279 DOI: 10.1016/S0006-291X(03)01254-3  0.34
2003 Zourlidou A, Payne Smith MD, Latchman DS. Modulation of cell death by α-synuclein is stimulus-dependent in mammalian cells Neuroscience Letters. 340: 234-238. PMID 12672549 DOI: 10.1016/S0304-3940(03)00081-8  0.302
2003 Kalwy SA, Akbar MT, Coffin RS, De Belleroche J, Latchman DS. Heat shock protein 27 delivered via a herpes simplex virus vector can protect neurons of the hippocampus against kainic-acid-induced cell loss Molecular Brain Research. 111: 91-103. PMID 12654509 DOI: 10.1016/S0169-328X(02)00692-7  0.373
2003 Akbar MT, Lundberg AM, Liu K, Vidyadaran S, Wells KE, Dolatshad H, Wynn S, Wells DJ, Latchman DS, de Belleroche J. The neuroprotective effects of heat shock protein 27 overexpression in transgenic animals against kainate-induced seizures and hippocampal cell death. The Journal of Biological Chemistry. 278: 19956-65. PMID 12639970 DOI: 10.1074/Jbc.M207073200  0.346
2003 Patel Y, Collaco Moraes Y, Latchman D, Coffin R, de Belleroche J. Neuroprotective effects of copper/zinc-dependent superoxide dismutase against a wide variety of death-inducing stimuli and proapoptotic effect of familial amyotrophic lateral sclerosis mutations. Brain Research. Molecular Brain Research. 109: 189-97. PMID 12531528 DOI: 10.1016/S0169-328X(02)00560-0  0.337
2003 Gusterson RJ, Jazrawi E, Adcock IM, Latchman DS. The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity Journal of Biological Chemistry. 278: 6838-6847. PMID 12477714 DOI: 10.1074/Jbc.M211762200  0.371
2002 Latchman DS. Herpes simplex virus vectors for gene delivery to a variety of different cell types Current Gene Therapy. 2: 415-426. PMID 12477253 DOI: 10.2174/1566523023347698  0.348
2002 Perez-Sanchez C, Budhram-Mahadeo VS, Latchman DS. Distinct promoter elements mediate the co-operative effect of Brn-3a and p53 on the p21 promoter and their antagonism on the Bax promoter Nucleic Acids Research. 30: 4872-4880. PMID 12433990 DOI: 10.1093/Nar/Gkf610  0.311
2002 Budhram-Mahadeo V, Morris P, Ndisang D, Irshad S, Lozano G, Pedley B, Latchman DS. The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells Neuroscience Letters. 334: 1-4. PMID 12431761 DOI: 10.1016/S0304-3940(02)00813-3  0.374
2002 Papageorgiou K, Isenberg DA, Latchman DS. Optimisation of herpes simplex virus-based vectors for delivery to human peripheral blood mononuclear cells Journal of Immunological Methods. 270: 235-246. PMID 12379328 DOI: 10.1016/S0022-1759(02)00299-5  0.312
2002 Stephanou A, Scarabelli TM, Townsend PA, Bell R, Yellon D, Knight RA, Latchman DS. The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1841-1843. PMID 12223448 DOI: 10.1096/Fj.02-0150Fje  0.32
2002 Budram-Mahadeo V, Morris PJ, Latchman DS. The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21CIP1/Waf1 Oncogene. 21: 6123-6131. PMID 12203124 DOI: 10.1038/Sj.Onc.1205842  0.353
2002 Kabakov AE, Budagova KR, Latchman DS, Kampinga HH. Stressful preconditioning and HSP70 overexpression attenuate proteotoxicity of cellular ATP depletion American Journal of Physiology - Cell Physiology. 283: C521-C534. PMID 12107062 DOI: 10.1152/Ajpcell.00503.2001  0.326
2002 Dennis JH, Budhram-Mahadeo V, Latchman DS. Functional interaction between Brn-3a and Src-1 co-activates Brn-3a-mediated transactivation Biochemical and Biophysical Research Communications. 294: 487-495. PMID 12051737 DOI: 10.1016/S0006-291X(02)00500-4  0.615
2002 Brar BK, Stephanou A, Knight R, Latchman DS. Activation of protein kinase B/Akt by urocortin is essential for its ability to protect cardiac cells against hypoxia/reoxygenation-induced cell death Journal of Molecular and Cellular Cardiology. 34: 483-492. PMID 11991736 DOI: 10.1006/Jmcc.2002.1529  0.302
2002 Latchman DS. Protection of neuronal and cardiac cells by HSP27 Progress in Molecular and Subcellular Biology. 28: 253-265. PMID 11908064 DOI: 10.1007/978-3-642-56348-5_14  0.343
2002 Thomas SK, Lilley CE, Latchman DS, Coffin RS. A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSV genome Journal of Virology. 76: 4056-4067. PMID 11907244 DOI: 10.1128/Jvi.76.8.4056-4067.2002  0.372
2002 Stephanou A, Scarabelli TM, Knight RA, Latchman DS. Antiapoptotic activity of the free caspase recruitment domain of procaspase-9. A novel endogenous rescue pathway in cell death Journal of Biological Chemistry. 277: 13693-13699. PMID 11825888 DOI: 10.1074/Jbc.M108530200  0.344
2002 Thomas GR, Latchman DS. The pro-oncoprotein EWS (Ewing's sarcoma protein) interacts with the Brn-3a POU transcription factor and inhibits its ability to activate transcription Cancer Biology and Therapy. 1: 428-432. DOI: 10.4161/Cbt.1.4.23  0.376
2001 Latchman DS. Gene therapy with herpes simplex virus vectors: Progress and prospects for clinical neuroscience Neuroscientist. 7: 528-537. PMID 11765130 DOI: 10.1177/107385840100700609  0.315
2001 Sugars KL, Budhram-Mahadeo V, Packham G, Latchman DS. A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53 Nucleic Acids Research. 29: 4530-4540. PMID 11713302 DOI: 10.1093/Nar/29.22.4530  0.348
2001 Smith MDP, Ensor EA, Kinloch RA, Latchman DS. The POU domain transcription factor Brn-3a protects cortical neurons from apoptosis Neuroreport. 12: 3183-3188. PMID 11711852 DOI: 10.1097/00001756-200110290-00008  0.327
2001 Latchman DS. Urocortin protects against ischemic injury via a MAPK-dependent pathway Trends in Cardiovascular Medicine. 11: 167-169. PMID 11597826 DOI: 10.1016/S1050-1738(01)00093-7  0.322
2001 Akbar MT, Wells DJ, Latchman DS, De Belleroche J. Heat shock protein 27 shows a distinctive widespread spatial and temporal pattern of induction in CNS glial and neuronal cells compared to heat shock protein 70 and caspase 3 following kainate administration Molecular Brain Research. 93: 148-163. PMID 11589992 DOI: 10.1016/S0169-328X(01)00199-1  0.326
2001 Latchman DS. Heat shock proteins and cardiac protection Cardiovascular Research. 51: 637-646. PMID 11530097 DOI: 10.1016/S0008-6363(01)00354-6  0.359
2001 Dennis JH, Budhram-Mahadeo V, Latchman DS. The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells Oncogene. 20: 4961-4971. PMID 11526481 DOI: 10.1038/Sj.Onc.1204491  0.617
2001 Ndisang D, Budhram-Mahadeo V, Pedley B, Latchman DS. The Brn-3a transcription factor plays a key role in regulating the growth of cervical cancer cells in vivo Oncogene. 20: 4899-4903. PMID 11521202 DOI: 10.1038/Sj.Onc.1204634  0.358
2001 Freeland K, Boxer LM, Latchman DS. The cyclic AMP response element in the Bcl-2 promoter confers inducibility by hypoxia in neuronal cells Molecular Brain Research. 92: 98-106. PMID 11483246 DOI: 10.1016/S0169-328X(01)00158-9  0.379
2001 Budhram-Mahadeo V, Moore A, Morris PJ, Ward T, Weber B, Sassone-Corsi P, Latchman DS. The closely related POU family transcription factors Brn-3a and Brn-3b are expressed in distinct cell types in the testis International Journal of Biochemistry and Cell Biology. 33: 1027-1039. PMID 11470235 DOI: 10.1016/S1357-2725(01)00069-3  0.366
2001 Latchman DS. Transcription factors as potential targets for therapeutic drugs. Current Pharmaceutical Biotechnology. 1: 57-61. PMID 11467361 DOI: 10.2174/1389201003379022  0.312
2001 Railson JE, Lawrence K, Buddle JC, Pennica D, Latchman DS. Heat shock protein-56 is induced by cardiotrophin-1 and mediates its hypertrophic effect Journal of Molecular and Cellular Cardiology. 33: 1209-1221. PMID 11444924 DOI: 10.1006/Jmcc.2001.1384  0.335
2001 Wright MJ, Wightman LM, Lilley C, de Alwis M, Hart SL, Miller A, Coffin RS, Thrasher A, Latchman DS, Marber MS. In vivo myocardial gene transfer: optimization, evaluation and direct comparison of gene transfer vectors. Basic Research in Cardiology. 96: 227-36. PMID 11403416 DOI: 10.1007/S003950170053  0.31
2001 Latchman DS. Transcription factors: bound to activate or repress. Trends in Biochemical Sciences. 26: 211-3. PMID 11295539 DOI: 10.1016/S0968-0004(01)01812-6  0.345
2001 Lilley CE, Groutsi F, Han Z, Palmer JA, Anderson PN, Latchman DS, Coffin RS. Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo Journal of Virology. 75: 4343-4356. PMID 11287583 DOI: 10.1128/Jvi.75.9.4343-4356.2001  0.331
2001 Smith MD, Melton LA, Ensor EA, Packham G, Anderson P, Kinloch RA, Latchman DS. Brn-3a activates the expression of Bcl-x(L) and promotes neuronal survival in vivo as well as in vitro. Molecular and Cellular Neurosciences. 17: 460-70. PMID 11273642 DOI: 10.1006/Mcne.2000.0927  0.343
2001 Latchman DS. Gene delivery and gene therapy with herpes simplex virus-based vectors. Gene. 264: 1-9. PMID 11245972 DOI: 10.1016/S0378-1119(01)00322-5  0.319
2001 Latchman DS, Coffin RS. Viral vectors for gene therapy in Parkinson's disease. Reviews in the Neurosciences. 12: 69-78. PMID 11236066 DOI: 10.1515/Revneuro.2001.12.1.69  0.323
2001 Railson J, Lawrence K, Stephanou A, Brar B, Pennica D, Latchman D. Cardiotrophin-1 reduces stress-induced heat shock protein production in cardiac myocytes. Cytokine. 12: 1741-4. PMID 11052830 DOI: 10.1006/Cyto.2000.0778  0.326
2001 Latchman DS. Gene therapy using herpes simplex virus-based vectors. Histology and Histopathology. 15: 1253-9. PMID 11005249 DOI: 10.14670/Hh-15.1253  0.312
2000 Ensor E, Smith MD, Latchman DS. The BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosis. The Journal of Biological Chemistry. 276: 5204-12. PMID 11053412 DOI: 10.1074/Jbc.M007068200  0.33
2000 Mockridge JW, Benton EC, Andreeva LV, Latchman DS, Marber MS, Heads RJ. IGF-1 regulates cardiac fibroblast apoptosis induced by osmotic stress. Biochemical and Biophysical Research Communications. 273: 322-7. PMID 10873605 DOI: 10.1006/Bbrc.2000.2934  0.315
2000 Palmer JA, Branston RH, Lilley CE, Robinson MJ, Groutsi F, Smith J, Latchman DS, Coffin RS. Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous system. Journal of Virology. 74: 5604-18. PMID 10823868 DOI: 10.1128/Jvi.74.12.5604-5618.2000  0.306
2000 Latchman DS. Cardiotrophin-1: a novel cytokine and its effects in the heart and other tissues. Pharmacology & Therapeutics. 85: 29-37. PMID 10674712 DOI: 10.1016/S0163-7258(99)00049-2  0.328
2000 Brar BK, Stephanou A, Okosi A, Lawrence KM, Knight RA, Marber MS, Latchman DS. CRH-like peptides protect cardiac myocytes from lethal ischaemic injury. Molecular and Cellular Endocrinology. 158: 55-63. PMID 10630405 DOI: 10.1016/S0303-7207(99)00183-5  0.31
2000 Budhram-Mahadeo V, Ndisang D, Ward T, Weber BL, Latchman DS. The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells. Oncogene. 18: 6684-91. PMID 10597274 DOI: 10.1038/Sj.Onc.1203072  0.352
2000 Ripley BJ, Stephanou A, Isenberg DA, Latchman DS. Interleukin-10 activates heat-shock protein 90beta gene expression. Immunology. 97: 226-31. PMID 10447736 DOI: 10.1046/J.1365-2567.1999.00773.X  0.313
2000 FREELAND K, LIU Y, LATCHMAN DS. Distinct signalling pathways mediate the cAMP response element (CRE)-dependent activation of the calcitonin gene-related peptide gene promoter by cAMP and nerve growth factor Biochemical Journal. 345: 233-238. DOI: 10.1042/Bj3450233  0.344
1999 Smith MD, Ensor EA, Stohl L, Wagner JA, Latchman DS. Regulation of NGFI-A (Egr-1) gene expression by the POU domain transcription factor Brn-3a Molecular Brain Research. 74: 117-125. PMID 10640682 DOI: 10.1016/S0169-328X(99)00271-5  0.391
1999 Ndisang D, Budhram-Mahadeo V, Latchman DS. The Brn-3a transcription factor plays a critical role in regulating human papilloma virus gene expression and determining the growth characteristics of cervical cancer cells. The Journal of Biological Chemistry. 274: 28521-7. PMID 10497216 DOI: 10.1074/Jbc.274.40.28521  0.312
1999 Thomas SK, Lilley CE, Latchman DS, Coffin RS. Equine herpesvirus 1 gene 12 can substitute for vmw65 in the growth of herpes simplex virus (HSV) type 1, allowing the generation of optimized cell lines for the propagation of HSV vectors with multiple immediate-early gene defects Journal of Virology. 73: 7399-7409. PMID 10438830 DOI: 10.1128/Jvi.73.9.7399-7409.1999  0.349
1999 Latchman DS. Regulation of DNA virus transcription by cellular POU family transcription factors. Reviews in Medical Virology. 9: 31-8. PMID 10371670 DOI: 10.1002/(Sici)1099-1654(199901/03)9:1<31::Aid-Rmv231>3.0.Co;2-2  0.368
1999 Brownlees J, Gough G, Thomas S, Watts P, Cohen J, Coffin R, Latchman DS. Distinct responses of the herpes simplex virus and varicella zoster virus immediate early promoters to the cellular transcription factors Brn-3a and Brn-3b. The International Journal of Biochemistry & Cell Biology. 31: 451-61. PMID 10224669 DOI: 10.1016/S1357-2725(98)00151-4  0.361
1999 Liu YZ, Boxer LM, Latchman DS. Activation of the Bcl-2 promoter by nerve growth factor is mediated by the p42/p44 MAPK cascade. Nucleic Acids Research. 27: 2086-90. PMID 10219080 DOI: 10.1093/Nar/27.10.2086  0.341
1999 Brar BK, Stephanou A, Wagstaff MJ, Coffin RS, Marber MS, Engelmann G, Latchman DS. Heat shock proteins delivered with a virus vector can protect cardiac cells against apoptosis as well as against thermal or hypoxic stress. Journal of Molecular and Cellular Cardiology. 31: 135-46. PMID 10072722 DOI: 10.1006/Jmcc.1998.0857  0.371
1999 Wagstaff MJ, Collaço-Moraes Y, Smith J, de Belleroche JS, Coffin RS, Latchman DS. Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector. The Journal of Biological Chemistry. 274: 5061-9. PMID 9988753 DOI: 10.1074/Jbc.274.8.5061  0.373
1999 Stephanou A, Isenberg DA, Nakajima K, Latchman DS. Signal transducer and activator of transcription-1 and heat shock factor-1 interact and activate the transcription of the Hsp-70 and Hsp-90beta gene promoters. The Journal of Biological Chemistry. 274: 1723-8. PMID 9880553 DOI: 10.1074/Jbc.274.3.1723  0.37
1999 Gay RD, Dawson SJ, Murphy WJ, Russell SW, Latchman DS. Activation of the iNOS gene promoter by Brn-3 POU family transcription factors is dependent upon the octamer motif in the promoter. Biochimica Et Biophysica Acta. 1443: 315-22. PMID 9878805 DOI: 10.1016/S0167-4781(98)00234-6  0.373
1999 Chapman CM, Latchman DS. The different alternatively spliced isoforms of the Oct-2 transcription factor repress the involucrin promoter in a cell type-specific manner. Molecular Biology Reports. 25: 253-7. PMID 9870616 DOI: 10.1023/A:1006801002594  0.379
1998 Wagstaff MJ, Lilley CE, Smith J, Robinson MJ, Coffin RS, Latchman DS. Gene transfer using a disabled herpes virus vector containing the EMCV IRES allows multiple gene expression in vitro and in vivo. Gene Therapy. 5: 1566-70. PMID 9930311 DOI: 10.1038/Sj.Gt.3300754  0.345
1998 Latchman DS. The Brn-3a transcription factor. The International Journal of Biochemistry & Cell Biology. 30: 1153-7. PMID 9839440 DOI: 10.1016/S1357-2725(98)00090-9  0.386
1998 Wagstaff MJ, Smith J, Collaco-Moraes Y, de Belleroche JS, Voellmy R, Coffin RS, Latchman DS. Delivery of a constitutively active form of the heat shock factor using a virus vector protects neuronal cells from thermal or ischaemic stress but not from apoptosis. The European Journal of Neuroscience. 10: 3343-50. PMID 9824447 DOI: 10.1046/J.1460-9568.1998.00339.X  0.379
1998 McMenamin MM, Byrnes AP, Pike FG, Charlton HM, Coffin RS, Latchman DS, Wood MJA. Potential and limitations of a γ34.5 mutant of herpes simplex 1 as a gene therapy vector in the CNS Gene Therapy. 5: 594-604. PMID 9797863 DOI: 10.1038/Sj.Gt.3300639  0.336
1998 Zhao J, Renner O, Wightman L, Sugden PH, Stewart L, Miller AD, Latchman DS, Marber MS. The expression of constitutively active isotypes of protein kinase C to investigate preconditioning. The Journal of Biological Chemistry. 273: 23072-9. PMID 9722533 DOI: 10.1074/Jbc.273.36.23072  0.309
1998 Dawson SJ, Palmer RD, Morris PJ, Latchman DS. Functional role of position 22 in the homeodomain of Brn-3 transcription factors. Neuroreport. 9: 2305-9. PMID 9694219 DOI: 10.1097/00001756-199807130-00029  0.38
1998 Stephanou A, Conroy S, Isenberg DA, Maione D, Poli V, Ciliberto G, Latchman DS. Elevation of IL-6 in transgenic mice results in increased levels of the 90 kDa heat shock protein (hsp90) and the production of anti-hsp90 antibodies. Journal of Autoimmunity. 11: 249-53. PMID 9693973 DOI: 10.1006/Jaut.1998.0194  0.302
1998 Patel Y, Gough G, Coffin RS, Thomas S, Cohen JI, Latchman DS. Cell type specific repression of the varicella zoster virus immediate early gene 62 promoter by the cellular Oct-2 transcription factor. Biochimica Et Biophysica Acta. 1397: 268-74. PMID 9582435 DOI: 10.1016/S0167-4781(97)00216-9  0.392
1998 Wyatt S, Ensor L, Begbie J, Ernfors P, Reichardt LF, Latchman DS. NT-3 regulates expression of Brn3a but not Brn3b in developing mouse trigeminal sensory neurons. Brain Research. Molecular Brain Research. 55: 254-64. PMID 9582431 DOI: 10.1016/S0169-328X(98)00006-0  0.329
1998 Smith MD, Morris PJ, Latchman DS. The Brn-3c transcription factor contains a neuronal-specific activation domain. Neuroreport. 9: 851-6. PMID 9579678 DOI: 10.1097/00001756-199803300-00016  0.383
1998 Budhram-Mahadeo V, Parker M, Latchman DS. POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element. Molecular and Cellular Biology. 18: 1029-41. PMID 9448000 DOI: 10.1128/Mcb.18.2.1029  0.336
1998 Latchman DS. How can we use our growing understanding of gene transcription to discover effective new medicines? Current Opinion in Biotechnology. 8: 713-7. PMID 9425662 DOI: 10.1016/S0958-1669(97)80125-5  0.336
1998 Thomas S, Coffin RS, Watts P, Gough G, Latchman DS. The TAATGARAT Motif in the Herpes Simplex Virus Immediate-Early Gene Promoters Can Confer both Positive and Negative Responses to Cellular Octamer-Binding Proteins When It Is Located within the Viral Genome Journal of Virology. 72: 3495-3500. DOI: 10.1128/Jvi.72.4.3495-3500.1998  0.348
1997 Deans ZC, Dawson SJ, Kilimann MW, Wallace D, Wilson MC, Latchman DS. Differential regulation of genes encoding synaptic proteins by the Oct-2 transcription factor. Brain Research. Molecular Brain Research. 51: 1-7. PMID 9427500 DOI: 10.1016/S0169-328X(97)00204-0  0.396
1997 Howard MK, Coffin RS, Maclean AR, Brown SM, Bailey D, Anderson PN, Burnstock G, Latchman DS. Gene delivery to rat enteric neurons using herpes simplex virus-based vectors. Journal of Molecular Neuroscience : Mn. 9: 65-74. PMID 9407388 DOI: 10.1007/Bf02736851  0.318
1997 Gay RD, Dawson SJ, Latchman DS. The different inhibitory domains of the Oct-2 transcription factor have distinct functional activities. Febs Letters. 416: 135-8. PMID 9369198 DOI: 10.1016/S0014-5793(97)01184-8  0.327
1997 Morris PJ, Dawson SJ, Wilson MC, Latchman DS. A single residue within the homeodomain of the Brn-3 POU family transcription factors determines whether they activate or repress the SNAP-25 promoter. Neuroreport. 8: 2041-5. PMID 9223099 DOI: 10.1097/00001756-199705260-00047  0.365
1997 Rose LM, Latchman DS, Isenberg DA. Apoptosis in peripheral lymphocytes in systemic lupus erythematosus: A review British Journal of Rheumatology. 36: 158-163. PMID 9133921 DOI: 10.1093/Rheumatology/36.2.158  0.314
1997 Stephanou A, Amin V, Isenberg DA, Akira S, Kishimoto T, Latchman DS. Interleukin 6 activates heat-shock protein 90 beta gene expression. The Biochemical Journal. 103-6. PMID 9003407 DOI: 10.1042/Bj3210103  0.303
1997 Smith MD, Dawson SJ, Latchman DS. Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor. The Journal of Biological Chemistry. 272: 1382-8. PMID 8995448 DOI: 10.1074/Jbc.272.2.1382  0.386
1997 Smith MD, Dawson SJ, Latchman DS. The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins. Molecular and Cellular Biology. 17: 345-54. PMID 8972215 DOI: 10.1128/Mcb.17.1.345  0.384
1997 Latchman DS. Inhibitory transcription factors. The International Journal of Biochemistry & Cell Biology. 28: 965-74. PMID 8930119 DOI: 10.1016/1357-2725(96)00039-8  0.333
1997 Kendall G, Crankson H, Ensor E, Lublin DM, Latchman DS. Activation of the gene encoding decay accelerating factor following nerve growth factor treatment of sensory neurons is mediated by promoter sequences within 206 bases of the transcriptional start site. Journal of Neuroscience Research. 45: 96-103. PMID 8843027 DOI: 10.1002/(Sici)1097-4547(19960715)45:2<96::Aid-Jnr2>3.0.Co;2-A  0.343
1997 Latchman DS. Activation and repression of gene expression by POU family transcription factors. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 351: 511-5. PMID 8735273 DOI: 10.1098/Rstb.1996.0049  0.376
1996 Morris PJ, Lakin ND, Dawson SJ, Ryabinin AE, Kilimann MW, Wilson MC, Latchman DS. Differential regulation of genes encoding synaptic proteins by members of the Brn-3 subfamily of POU transcription factors. Brain Research. Molecular Brain Research. 43: 279-85. PMID 9037543 DOI: 10.1016/S0169-328X(96)00207-0  0.382
1996 Wagstaff MJ, Collaço-Moraes Y, Aspey BS, Coffin RS, Harrison MJ, Latchman DS, de Belleroche JS. Focal cerebral ischaemia increases the levels of several classes of heat shock proteins and their corresponding mRNAs. Brain Research. Molecular Brain Research. 42: 236-44. PMID 9013779 DOI: 10.1016/S0169-328X(96)00127-1  0.303
1996 Watson A, Latchman D. Gene Delivery into Neuronal Cells by Calcium Phosphate-Mediated Transfection Methods. 10: 289-291. PMID 8954840 DOI: 10.1006/Meth.1996.0105  0.328
1996 Deans Z, Dawson SJ, Xie J, Young AP, Wallace D, Latchman DS. Differential regulation of the two neuronal nitric-oxide synthase gene promoters by the Oct-2 transcription factor. The Journal of Biological Chemistry. 271: 32153-8. PMID 8943269 DOI: 10.1074/Jbc.271.50.32153  0.4
1996 Latchman DS. The Oct-2 transcription factor. The International Journal of Biochemistry & Cell Biology. 28: 1081-3. PMID 8930131 DOI: 10.1016/1357-2725(96)00050-7  0.414
1996 Ensor E, Kendall G, Allchorne A, Woolf CJ, Latchman DS. Induction of the Oct-2 transcription factor in primary sensory neurons during inflammation is nerve growth factor-dependent. Neuroscience Letters. 204: 29-32. PMID 8929970 DOI: 10.1016/0304-3940(96)12308-9  0.323
1996 Amin V, Cumming DV, Latchman DS. Over-expression of heat shock protein 70 protects neuronal cells against both thermal and ischaemic stress but with different efficiencies. Neuroscience Letters. 206: 45-8. PMID 8848278 DOI: 10.1016/0304-3940(96)12421-6  0.33
1996 Liu YZ, Dawson SJ, Latchman DS. Alternative splicing of the Brn-3a and Brn-3b transcription factor RNAs is regulated in neuronal cells. Journal of Molecular Neuroscience : Mn. 7: 77-85. PMID 8835784 DOI: 10.1007/Bf02736850  0.392
1996 Galea-Lauri J, Latchman DS, Katz DR. The role of the 90-kDa heat shock protein in cell cycle control and differentiation of the monoblastoid cell line U937. Experimental Cell Research. 226: 243-54. PMID 8806428 DOI: 10.1006/Excr.1996.0225  0.344
1996 Wyatt S, Mailhos C, Latchman DS. Trigeminal ganglion neurons are protected by the heat shock proteins hsp70 and hsp90 from thermal stress but not from programmed cell death following nerve growth factor withdrawal Molecular Brain Research. 39: 52-56. PMID 8804713 DOI: 10.1016/0169-328X(95)00352-S  0.341
1996 Smith MD, Latchman DS. The functionally antagonistic POU family transcription factors Brn-3a and Brn-3b show opposite changes in expression during the growth arrest and differentiation of human neuroblastoma cells. International Journal of Cancer. 67: 653-60. PMID 8782654 DOI: 10.1002/(Sici)1097-0215(19960904)67:5<653::Aid-Ijc11>3.0.Co;2-6  0.361
1996 Begbie JL, Wood JN, Anderson PN, Latchman DS. Specific up-regulation of the POU domain transcription factor Oct-2 following axotomy. Neuroscience Letters. 207: 183-6. PMID 8728480 DOI: 10.1016/0304-3940(96)12514-3  0.359
1996 Milton NG, Bessis A, Changeux JP, Latchman DS. Differential regulation of neuronal nicotinic acetylcholine receptor subunit gene promoters by Brn-3 POU family transcription factors. The Biochemical Journal. 317: 419-23. PMID 8713067 DOI: 10.1042/Bj3170419  0.323
1996 Liu YZ, Dawson SJ, Gerster T, Friedl E, Pengue G, Matthias P, Lania L, Latchman DS. The ability of the inhibitory domain of the POU family transcription factor Oct-2 to interfere with promoter activation by different classes of activation domains is dependent upon the nature of the basal promoter elements. The Journal of Biological Chemistry. 271: 20853-60. PMID 8702841 DOI: 10.1074/Jbc.271.34.20853  0.306
1996 Deans Z, Dawson SJ, Buttery L, Polak JM, Wallace D, Latchman DS. Direct evidence that the POU family transcription factor Oct-2 represses the cellular tyrosine hydroxylase gene in neuronal cells. Journal of Molecular Neuroscience : Mn. 6: 159-67. PMID 8672399 DOI: 10.1007/Bf02736762  0.388
1996 Dawson SJ, Liu YZ, Rodel B, Möröy T, Latchman DS. The ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elements. The Biochemical Journal. 439-43. PMID 8670054 DOI: 10.1042/Bj3140439  0.363
1996 Dawson SJ, Morris PJ, Latchman DS. A single amino acid change converts an inhibitory transcription factor into an activator. The Journal of Biological Chemistry. 271: 11631-3. PMID 8662774 DOI: 10.1074/Jbc.271.20.11631  0.308
1996 Budhram-Mahadeo V, Morris PJ, Lakin ND, Dawson SJ, Latchman DS. The different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding site. The Journal of Biological Chemistry. 271: 9108-13. PMID 8621561 DOI: 10.1074/Jbc.271.15.9108  0.324
1996 Amin V, Cumming DV, Coffin RS, Latchman DS. The degree of protection provided to neuronal cells by a pre-conditioning stress correlates with the amount of heat shock protein 70 it induces and not with the similarity of the subsequent stress. Neuroscience Letters. 200: 85-8. PMID 8614569 DOI: 10.1016/0304-3940(95)12074-E  0.3
1996 Heads RJ, Latchman DS, Yellon DM. Differential stress protein mRNA expression during early ischaemic preconditioning in the rabbit heart and its relationship to adenosine receptor function. Journal of Molecular and Cellular Cardiology. 27: 2133-48. PMID 8576930 DOI: 10.1016/S0022-2828(95)91299-1  0.332
1996 Lillycrop KA, Latchman DS. The inhibitory domain in the Oct-2 transcription factor represses gene activity in a cell type-specific and promoter-independent manner. Molecular Biology Reports. 21: 87-94. PMID 8531926 DOI: 10.1007/Bf00986498  0.341
1996 Heads RJ, Yellon DM, Latchman DS. Differential cytoprotection against heat stress or hypoxia following expression of specific stress protein genes in myogenic cells. Journal of Molecular and Cellular Cardiology. 27: 1669-78. PMID 8523429 DOI: 10.1016/S0022-2828(95)90722-X  0.335
1996 Latchman DS. Transcription-factor mutations and disease. The New England Journal of Medicine. 334: 28-33. PMID 7494569 DOI: 10.1056/Nejm199601043340108  0.354
1995 Ryabinin AE, Sato TN, Morris PJ, Latchman DS, Wilson MC. Immediate upstream promoter regions required for neurospecific expression of SNAP-25. Journal of Molecular Neuroscience : Mn. 6: 201-10. PMID 8672402 DOI: 10.1007/Bf02736765  0.35
1995 Kendall G, Ensor E, Brar-Rai A, Winter J, Latchman DS. Nerve growth factor induces expression of immediate-early genes NGFI-A (Egr-1) and NGFI-B (nur 77) in adult rat dorsal root ganglion neurons. Brain Research. Molecular Brain Research. 25: 73-9. PMID 7984055 DOI: 10.1016/0169-328X(94)90280-1  0.346
1995 Latchman DS. Herpes simplex virus vectors for gene therapy. Molecular Biotechnology. 2: 179-95. PMID 7866875 DOI: 10.1007/Bf02824809  0.301
1995 Budhram-Mahadeo V, Morris PJ, Lakin ND, Theil T, Ching GY, Lillycrop KA, Möröy T, Liem RK, Latchman DS. Activation of the alpha-internexin promoter by the Brn-3a transcription factor is dependent on the N-terminal region of the protein. The Journal of Biological Chemistry. 270: 2853-8. PMID 7852360 DOI: 10.1074/Jbc.270.6.2853  0.348
1995 Lakin ND, Morris PJ, Theil T, Sato TN, Möröy T, Wilson MC, Latchman DS. Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor. The Journal of Biological Chemistry. 270: 15858-63. PMID 7797590 DOI: 10.1074/Jbc.270.26.15858  0.4
1995 Milton NG, Bessis A, Changeux JP, Latchman DS. The neuronal nicotinic acetylcholine receptor alpha 2 subunit gene promoter is activated by the Brn-3b POU family transcription factor and not by Brn-3a or Brn-3c. The Journal of Biological Chemistry. 270: 15143-7. PMID 7797498 DOI: 10.1074/Jbc.270.25.15143  0.343
1995 Rose LM, Latchman DS, Isenberg DA. Bcl-2 expression is unaltered in unfractionated peripheral blood mononuclear cells in patients with systemic lupus erythematosus Rheumatology. 34: 316-320. PMID 7788144 DOI: 10.1093/Rheumatology/34.4.316  0.313
1995 Coffin RS, Howard MK, Latchman DS. Altered dinucleotide content within the latently transcribed regions of the DNA of alpha herpes viruses - Implications for latent RNA expression and DNA structure Virology. 209: 358-365. PMID 7778270 DOI: 10.1006/Viro.1995.1267  0.314
1995 Watson A, Ensor E, Symes A, Winter J, Kendall G, Latchman D. A minimal CGRP gene promoter is inducible by nerve growth factor in adult rat dorsal root ganglion neurons but not in PC12 phaeochromocytoma cells European Journal of Neuroscience. 7: 394-400. PMID 7773437 DOI: 10.1111/J.1460-9568.1995.Tb00335.X  0.364
1995 Huntriss JD, Twomey BM, Isenberg DA, Latchman DS. Enhanced transcription of the gene encoding the SmN autoantigen in patients with systemic lupus erythematosus does not result in enhanced levels of the SmN protein. Autoimmunity. 19: 81-7. PMID 7772706 DOI: 10.3109/08916939409009535  0.373
1995 Liu YZ, Lillycrop KA, Latchman DS. Regulated splicing of the Oct-2 transcription factor RNA in neuronal cells. Neuroscience Letters. 183: 8-12. PMID 7746493 DOI: 10.1016/0304-3940(94)11102-O  0.381
1995 Kendall G, Brar-Rai A, Ensor E, Winter J, Wood JN, Latchman DS. Nerve growth factor induces the Oct-2 transcription factor in sensory neurons with the kinetics of an immediate-early gene. Journal of Neuroscience Research. 40: 169-76. PMID 7745610 DOI: 10.1002/Jnr.490400205  0.355
1995 Lillycrop KA, Liu YZ, Theil T, Möröy T, Latchman DS. Activation of the herpes simplex virus immediate-early gene promoters by neuronally expressed POU family transcription factors. The Biochemical Journal. 581-4. PMID 7733899 DOI: 10.1042/Bj3070581  0.391
1995 Budhram-Mahadeo V, Lillycrop KA, Latchman DS. The levels of the antagonistic POU family transcription factors Brn-3a and Brn-3b in neuronal cells are regulated in opposite directions by serum growth factors. Neuroscience Letters. 185: 48-51. PMID 7731552 DOI: 10.1016/0304-3940(94)11222-5  0.366
1995 Watson A, Latchman D. The cyclic AMP response element in the calcitonin/calcitonin gene-related peptide gene promoter is necessary but not sufficient for its activation by nerve growth factor. The Journal of Biological Chemistry. 270: 9655-60. PMID 7721899 DOI: 10.1074/Jbc.270.16.9655  0.318
1995 Lakin ND, Palmer R, Lillycrop KA, Howard MK, Burke LC, Thomas NSB, Latchman DS. Down regulation of the octamer binding protein Oct-1 during growth arrest and differentiation of a neuronal cell line Molecular Brain Research. 28: 47-54. PMID 7707877 DOI: 10.1016/0169-328X(94)00183-F  0.363
1995 Latchman DS, Isenberg DA. The role of hsp90 in SLE. Autoimmunity. 19: 211-8. PMID 7605872 DOI: 10.3109/08916939408995696  0.314
1994 Twomey BM, Amin V, Isenberg DA, Latchman DS. Elevated levels of the 70 kD heat shock protein in patients with systemic lupus erythematosus are not dependent on enhanced transcription of the hsp70 gene. Lupus. 2: 297-301. PMID 8305922 DOI: 10.1177/096120339300200504  0.34
1994 Lillycrop KA, Howard MK, Estridge JK, Latchman DS. Inhibition of herpes simplex virus infection by ectopic expression of neuronal splice variants of the Oct-2 transcription factor Nucleic Acids Research. 22: 815-820. PMID 8139923 DOI: 10.1093/Nar/22.5.815  0.354
1994 Lillycrop KA, Estridge JK, Latchman DS. Functional interaction between different isoforms of the Oct-2 transcription factor expressed in neuronal cells. The Biochemical Journal. 245-8. PMID 8129727 DOI: 10.1042/Bj2980245  0.379
1994 Mailhos C, Howard MK, Latchman DS. A common pathway mediates retinoic acid and PMA-dependent programmed cell death (apoptosis) of neuronal cells Brain Research. 644: 7-12. PMID 8032951 DOI: 10.1016/0006-8993(94)90339-5  0.305
1994 Budhram-Mahadeo V, Lillycrop KA, Latchman DS. Cell cycle arrest and morphological differentiation can occur in the absence of apoptosis in a neuronal cell line. Neuroscience Letters. 165: 18-22. PMID 8015721 DOI: 10.1016/0304-3940(94)90699-8  0.336
1994 Lillycrop KA, Dawson SJ, Estridge JK, Gerster T, Matthias P, Latchman DS. Repression of a herpes simplex virus immediate-early promoter by the Oct-2 transcription factor is dependent on an inhibitory region at the N terminus of the protein. Molecular and Cellular Biology. 14: 7633-42. PMID 7935477 DOI: 10.1128/Mcb.14.11.7633  0.357
1994 Morris PJ, Theil T, Ring CJ, Lillycrop KA, Moroy T, Latchman DS. The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain. Molecular and Cellular Biology. 14: 6907-14. PMID 7935408 DOI: 10.1128/Mcb.14.10.6907  0.329
1994 Mailhos C, Howard MK, Latchman DS. Heat shock proteins hsp90 and hsp70 protect neuronal cells from thermal stress but not from programmed cell death Journal of Neurochemistry. 63: 1787-1795. PMID 7931334 DOI: 10.1046/J.1471-4159.1994.63051787.X  0.337
1994 Conroy SE, Faulds GB, Williams W, Latchman DS, Isenberg DA. Detection of autoantibodies to the 90 kDa heat shock protein in systemic lupus erythematosus and other autoimmune diseases. British Journal of Rheumatology. 33: 923-6. PMID 7921751 DOI: 10.1093/Rheumatology/33.10.923  0.305
1994 Dawson SJ, Yoon SO, Chikaraishi DM, Lillycrop KA, Latchman DS. The Oct-2 transcription factor represses tyrosine hydroxylase expression via a heptamer TAATGARAT-like motif in the gene promoter. Nucleic Acids Research. 22: 1023-8. PMID 7908738 DOI: 10.1093/Nar/22.6.1023  0.386
1994 Huntriss JD, Barr JA, Horn DA, Williams DG, Latchman DS. Mice lacking Snrpn expression show normal regulation of neuronal alternative splicing events. Molecular Biology Reports. 20: 19-25. PMID 7845394 DOI: 10.1007/Bf00999851  0.336
1994 Rose LM, Latchman DS, Isenberg DA. Bcl-2 and fas, molecules which influence apoptosis. A possible role in systemic lupus erythematosus? Autoimmunity. 17: 271-278. PMID 7524704 DOI: 10.3109/08916939409010667  0.327
1993 Gerrelli D, Grimaldi K, Horn D, Mahadeva U, Sharpe N, Latchman DS. The cardiac form of the tissue-specific SmN protein is identical to the brain and embryonic forms of the protein. Journal of Molecular and Cellular Cardiology. 25: 321-9. PMID 8510173 DOI: 10.1006/Jmcc.1993.1038  0.349
1993 Horn DA, Latchman DS. A distal region of the CALC-1 gene is necessary for regulated alternative splicing. Febs Letters. 324: 123-6. PMID 8508914 DOI: 10.1016/0014-5793(93)81376-B  0.33
1993 Mailhos C, Howard MK, Latchman DS. Heat shock protects neuronal cells from programmed cell death by apoptosis Neuroscience. 55: 621-627. PMID 8413925 DOI: 10.1016/0306-4522(93)90428-I  0.339
1993 Horn DA, Latchman DS. The tissue specific SmN protein does not influence the alternative splicing of endogenous N-Cam and C-SRC RNAs in transfected 3T3 cells. Brain Research. Molecular Brain Research. 19: 181-7. PMID 8412559 DOI: 10.1016/0169-328X(93)90024-J  0.317
1993 Dhillon V, McCallum S, Wilks D, Twomey B, Latchman D, Isenberg D. The differential expression of heat shock proteins in rheumatic disease. British Journal of Rheumatology. 32: 883-92. PMID 8401997 DOI: 10.1093/Rheumatology/32.10.883  0.314
1993 Lillycrop KA, Estridge JK, Latchman DS. The octamer binding protein Oct-2 inhibits transactivation of the herpes simplex virus immediate-early genes by the virion protein Vmw65. Virology. 196: 888-91. PMID 8396817 DOI: 10.1006/Viro.1993.1552  0.396
1993 Howard MK, Burke LC, Mailhos C, Pizzey A, Gilbert CS, Lawson WD, Collins MKL, Thomas NSB, Latchman DS. Cell cycle arrest of proliferating neuronal cells by serum deprivation can result in either apoptosis or differentiation Journal of Neurochemistry. 60: 1783-1791. PMID 8386223 DOI: 10.1111/J.1471-4159.1993.Tb13404.X  0.326
1993 Huntriss JD, Latchman DS, Williams DG. The snRNP core protein SmB and tissue-specific SmN protein are differentially distributed between snRNP particles. Nucleic Acids Research. 21: 4047-53. PMID 8371979 DOI: 10.1093/Nar/21.17.4047  0.318
1993 Horn DA, Latchman DS. Alternative splicing of the mRNA encoding the alpha subunits of the G(o) GTP-binding protein during brain development and in neuronal cell lines. Neuroscience Letters. 155: 57-60. PMID 8361664 DOI: 10.1016/0304-3940(93)90672-8  0.325
1993 Twomey BM, McCallum S, Isenberg DA, Latchman DS. Elevation of heat shock protein synthesis and hsp gene transcription during monocyte to macrophage differentiation of U937 cells. Clinical and Experimental Immunology. 93: 178-83. PMID 8348742 DOI: 10.1111/J.1365-2249.1993.Tb07962.X  0.348
1993 Ring CJ, Latchman DS. The human Brn-3b POU transcription factor shows only limited homology to the Brn-3a/RDC-1 factor outside the conserved POU domain. Nucleic Acids Research. 21: 2946. PMID 8332509 DOI: 10.1093/Nar/21.12.2946  0.312
1993 Morris PJ, Ring CJ, Lillycrop KA, Latchman DS. Transactivation of the human papilloma virus 16 octamer motif by the octamer binding protein Oct-2 requires both the N and C terminal activation domains. Nucleic Acids Research. 21: 4506-10. PMID 8233784 DOI: 10.1093/Nar/21.19.4506  0.342
1993 Twomey BM, Dhillon VB, McCallum S, Isenberg DA, Latchman DS. Elevated levels of the 90 kD heat shock protein in patients with systemic lupus erythematosus are dependent upon enhanced transcription of the hsp90 beta gene. Journal of Autoimmunity. 6: 495-506. PMID 8216691 DOI: 10.1006/Jaut.1993.1041  0.338
1993 Erkeller-Yüksel FM, Isenberg DA, Dhillon VB, Latchman DS, Lydyard PM. Surface expression of heat shock protein 90 by blood mononuclear cells from patients with systemic lupus erythematosus. Journal of Autoimmunity. 5: 803-14. PMID 1489490 DOI: 10.1016/0896-8411(92)90194-U  0.306
1993 Twomey B, McCallum S, Dhillon V, Isenberg D, Latchman D. Transcription of the genes encoding the small heat shock protein ubiquitin is unchanged in patients with systemic lupus erythematosus. Autoimmunity. 13: 197-200. PMID 1335295 DOI: 10.3109/08916939209004824  0.353
1992 Chapman CJ, Harris JD, Hardwicke MA, Sandri-Goldin RM, Collins MK, Latchman DS. Promoter-independent activation of heterologous virus gene expression by the herpes simplex virus immediate-early protein ICP27. Virology. 186: 573-8. PMID 1733102 DOI: 10.1016/0042-6822(92)90023-I  0.371
1992 Timmons PM, Brickell PM, Latchman DS, Rigby PW. Activation of endogenous retroviral transcription in SV40-transformed mouse cells. Nucleic Acids Research. 19: 7215-8. PMID 1662812 DOI: 10.1093/Nar/19.25.7215  0.328
1992 Grimaldi K, Gerrelli D, Sharpe NG, Lund T, Latchman DS. The intronless mouse gene for the tissue specific splicing protein SmN is a processed pseudogene containing a stop codon after thirty-one amino acids. Dna Sequence : the Journal of Dna Sequencing and Mapping. 2: 241-6. PMID 1627828 DOI: 10.3109/10425179209020809  0.335
1992 Orchard K, Lang G, Collins M, Latchman D. Characterization of a novel T lymphocyte protein which binds to a site related to steroid/thyroid hormone receptor response elements in the negative regulatory sequence of the human immunodeficiency virus long terminal repeat. Nucleic Acids Research. 20: 5429-34. PMID 1437560 DOI: 10.1093/Nar/20.20.5429  0.311
1992 Horn DA, Latchman DS. Neuronal expression of the tissue specific splicing protein SmN and its possible role in pre mRNA splicing. Biochemical Society Transactions. 20: 266S. PMID 1426556 DOI: 10.1042/Bst020266S  0.328
1992 Lillycrop KA, Budrahan VS, Lakin ND, Terrenghi G, Wood JN, Polak JM, Latchman DS. A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells. Nucleic Acids Research. 20: 5093-6. PMID 1383937 DOI: 10.1093/Nar/20.19.5093  0.391
1992 Wheatley SC, Dent CL, Wood JN, Latchman DS. Elevation of cyclic AMP levels in cell lines derived from latently infectable sensory neurons increases their permissivity for herpes virus infection by activating the viral immediate-early 1 gene promoter. Brain Research. Molecular Brain Research. 12: 149-54. PMID 1372062 DOI: 10.1016/0169-328X(92)90078-P  0.329
1992 Suburo AM, Wheatley SC, Horn DA, Gibson SJ, Jahn R, Fischer-Colbrie R, Wood JN, Latchman DS, Polak JM. Intracellular redistribution of neuropeptides and secretory proteins during differentiation of neuronal cell lines. Neuroscience. 46: 881-9. PMID 1347412 DOI: 10.1016/0306-4522(92)90191-4  0.332
1992 Horn DA, Suburo A, Terenghi G, Hudson LD, Polak JM, Latchman DS. Expression of the tissue specific splicing protein SmN in neuronal cell lines and in regions of the brain with different splicing capacities. Brain Research. Molecular Brain Research. 16: 13-9. PMID 1334191 DOI: 10.1016/0169-328X(92)90188-H  0.37
1991 Sharpe NG, Williams DG, Latchman DS. Regulated expression of the small nuclear ribonucleoprotein particle protein SmN in embryonic stem cell differentiation. Molecular and Cellular Biology. 10: 6817-20. PMID 2174118 DOI: 10.1128/Mcb.10.12.6817  0.328
1991 Dent CL, Lillycrop KA, Estridge JK, Thomas NS, Latchman DS. The B-cell and neuronal forms of the octamer-binding protein Oct-2 differ in DNA-binding specificity and functional activity. Molecular and Cellular Biology. 11: 3925-30. PMID 2072899 DOI: 10.1128/Mcb.11.8.3925  0.398
1991 Lea I, Moore HD, Latchman DS. Differential expression of the mouse U1a and U1b SnRNA genes is not dependent on sequence differences in the octamer motif. The Biochemical Journal. 719-22. PMID 1872807 DOI: 10.1042/Bj2770719  0.365
1991 Wheatley SC, Dent CL, Wood JN, Latchman DS. A cellular factor binding to the TAATGARAT DNA sequence prevents the expression of the HSV immediate-early genes following infection of nonpermissive cell lines derived from dorsal root ganglion neurons. Experimental Cell Research. 194: 78-82. PMID 1849828 DOI: 10.1016/0014-4827(91)90132-E  0.383
1991 Jang Kl, Pulverer B, Woodgett JR, Latchman DS. Activation of the cellular transcription factor AP-1 in herpes simplex virus infected cells is dependent on the viral immediate-early protein ICPO Nucleic Acids Research. 19: 4879-4883. PMID 1656381 DOI: 10.1093/Nar/19.18.4879  0.363
1991 Lillycrop KA, Dent CL, Wheatley SC, Beech MN, Ninkina NN, Wood JN, Latchman DS. The octamer-binding protein Oct-2 represses HSV immediate-early genes in cell lines derived from latently infectable sensory neurons. Neuron. 7: 381-90. PMID 1654947 DOI: 10.1016/0896-6273(91)90290-G  0.386
1991 Bansal GS, Norton PM, Latchman DS. The 90-kDa heat shock protein protects mammalian cells from thermal stress but not from viral infection. Experimental Cell Research. 195: 303-6. PMID 1649055 DOI: 10.1016/0014-4827(91)90377-7  0.335
1990 Perkins ND, Orchard KH, Collins ML, Latchman DS, Goodwin GH. Detection in non-erythroid cells of a factor with the binding characteristics of the erythroid cell transcription factor EF1. The Biochemical Journal. 269: 543-5. PMID 2386492 DOI: 10.1042/Bj2690543  0.365
1990 Estridge JK, Kemp LM, Latchman DS. The herpes simplex virus protein Vmw65 can trans-activate both viral and cellular promoters in neuronal cells. The Biochemical Journal. 271: 273-6. PMID 2171502 DOI: 10.1042/Bj2710273  0.397
1990 Wheatley SC, Kemp LM, Wood JN, Latchman DS. Cell lines derived from dorsal root ganglion neurons are nonpermissive for HSV and express only the latency-associated transcript following infection. Experimental Cell Research. 190: 243-6. PMID 2170153 DOI: 10.1016/0014-4827(90)90192-D  0.346
1990 Zwaagstra JC, Ghiasi H, Slanina SM, Nesburn AB, Wheatley SC, Lillycrop K, Wood J, Latchman DS, Patel K, Wechsler SL. Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript. Journal of Virology. 64: 5019-28. PMID 2168984 DOI: 10.1128/Jvi.64.10.5019-5028.1990  0.353
1990 Dent CL, Estridge JK, Kemp LM, Latchman DS. Inhibition of histone H2B gene transcription and of cellular growth by a truncated viral trans-activator protein. Molecular and Cellular Biology. 10: 3258-61. PMID 2160597 DOI: 10.1128/Mcb.10.6.3258  0.389
1990 Kemp LM, Dent CL, Latchman DS. Octamer motif mediates transcriptional repression of HSV immediate-early genes and octamer-containing cellular promoters in neuronal cells. Neuron. 4: 215-22. PMID 2155008 DOI: 10.1016/0896-6273(90)90096-X  0.398
1990 Wood JN, Bevan SJ, Coote PR, Dunn PM, Harmar A, Hogan P, Latchman DS, Morrison C, Rougon G, Theveniau M. Novel cell lines display properties of nociceptive sensory neurons. Proceedings. Biological Sciences / the Royal Society. 241: 187-94. PMID 1979443 DOI: 10.1098/Rspb.1990.0084  0.337
1990 Orchard K, Perkins N, Chapman C, Harris J, Emery V, Goodwin G, Latchman D, Collins M. A novel T-cell protein which recognizes a palindromic sequence in the negative regulatory element of the human immunodeficiency virus long terminal repeat. Journal of Virology. 64: 3234-3239. DOI: 10.1128/Jvi.64.7.3234-3239.1990  0.316
1989 Davis JM, La Thangue NB, Taylor DL, Latchman DS, Anderson M, Tyms AS. Cellular polypeptides overexpressed after herpes simplex infection permit virus subtyping and may help diagnose cervical cancer. Genitourinary Medicine. 64: 321-6. PMID 2849592 DOI: 10.1136/Sti.64.5.321  0.324
1989 Sharpe NG, Williams DG, Norton P, Latchman DS. Expression of the SmB' splicing protein in rodent cells capable of following an alternative RNA splicing pathway. Febs Letters. 243: 132-6. PMID 2783916 DOI: 10.1016/0014-5793(89)80114-0  0.33
1989 Sharpe NG, Williams DG, Howarth DN, Coles B, Latchman DS. Isolation of cDNA clones encoding the human Sm B/B' auto-immune antigen and specifically reacting with human anti-Sm auto-immune sera. Febs Letters. 250: 585-90. PMID 2753153 DOI: 10.1016/0014-5793(89)80801-4  0.301
1989 Estridge JK, Kemp LM, La Thangue NB, Mann BS, Tyms AS, Latchman DS. The herpes simplex virus type 1 immediate-early protein ICP27 is obligately required for the accumulation of a cellular protein during viral infection. Virology. 168: 67-72. PMID 2535908 DOI: 10.1016/0042-6822(89)90404-2  0.327
1989 SHARPE NG, WILLIAMS DG, NORTON PM, LATCHMAN DS. Cell-type specific expression of the SmB' splicing protein and alternative RNA splicing Biochemical Society Transactions. 17: 357-358. DOI: 10.1042/Bst0170357  0.304
1988 La Thangue NB, Latchman DS. A cellular protein related to heat-shock protein 90 accumulates during herpes simplex virus infection and is overexpressed in transformed cells. Experimental Cell Research. 178: 169-79. PMID 2842174 DOI: 10.1016/0014-4827(88)90388-6  0.334
1988 Kemp LM, Latchman DS. Induction and repression of cellular gene transcription during herpes simplex virus infection are mediated by different viral immediate-early gene products. European Journal of Biochemistry. 174: 443-9. PMID 2838278 DOI: 10.1111/J.1432-1033.1988.Tb14118.X  0.346
1988 LaThangue NB, Latchman DS. Nuclear accumulation of a heat-shock 70-like protein during herpes simplex virus replication. Bioscience Reports. 7: 475-83. PMID 2827804 DOI: 10.1007/Bf01116504  0.322
1987 Latchman DS, Estridge JK, Kemp LM. Transcriptional induction of the ubiquitin gene during herpes simplex virus infection is dependent upon the viral immediate-early protein ICP4. Nucleic Acids Research. 15: 7283-93. PMID 2821506 DOI: 10.1093/Nar/15.18.7283  0.372
1987 Latchman DS, Chan WL, Leaver CE, Patel R, Oliver P, La Thangue NB. The human Mr 90,000 heat shock protein and the Escherichia coli Lon protein share an antigenic determinant. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 87: 961-7. PMID 2444389 DOI: 10.1016/0305-0491(87)90419-6  0.321
1986 Patel R, Chan WL, Kemp LM, La Thangue NB, Latchman DS. Isolation of cDNA clones derived from a cellular gene transcriptionally induced by herpes simplex virus. Nucleic Acids Research. 14: 5629-40. PMID 3016658 DOI: 10.1093/Nar/14.14.5629  0.358
1986 Kemp LM, Brickell PM, Thangue NBL, Latchman DS. Transcriptional induction of cellular gene expression during lytic infection with herpes simplex virus Bioscience Reports. 6: 945-951. PMID 2883998 DOI: 10.1007/Bf01114970  0.337
1985 Rigby PW, Brickell PM, Latchman DS, Murphy D, Westphal KH, Willison K. The activation of cellular genes in transformed cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 347-51. PMID 6151708 DOI: 10.1098/Rstb.1984.0138  0.33
1985 Brickell PM, Latchman DS, Murphy D, Willison K, Rigby PW. The class I major histocompatibility antigen gene activated in a line of SV40-transformed mouse cells is H-2Dd, not Qa/Tla. Nature. 316: 162-3. PMID 2989712 DOI: 10.1038/316162A0  0.304
1984 Murphy D, Brickell PM, Latchman DS, Willison K, Rigby PW. Transcripts regulated during normal embryonic development and oncogenic transformation share a repetitive element. Cell. 35: 865-71. PMID 6652687 DOI: 10.1016/0092-8674(83)90119-8  0.317
1984 Brickell PM, Latchman DS, Murphy D, Willison K, Rigby PW. Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse. Nature. 306: 756-60. PMID 6318117 DOI: 10.1038/306756A0  0.338
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