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William L. Fitch - Publications

Affiliations: 
Chemistry & Biochemistry University of California, Santa Cruz, Santa Cruz, CA, United States 
Area:
Drug Metabolism and Mass Spectrometry
Website:
http://med.stanford.edu/peltzlab/members/

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Fitch WL, Khojasteh SC, Aliagas I, Johnson K. Using LC Retention Times in Organic Structure Determination: Drug Metabolite Identification. Drug Metabolism Letters. PMID 30070179 DOI: 10.2174/1872312812666180802093347  0.329
2018 Sun W, Nguyen KD, Fitch WL, Banister SD, Tang H, Zhang X, Yu L, Engleman EG, Rajadas J. In vitro and in vivo metabolite identification of a novel benzimidazole compound ZLN005 by LC-MS/MS. Rapid Communications in Mass Spectrometry : Rcm. PMID 29334584 DOI: 10.1002/Rcm.8060  0.312
2012 Bolleddula J, Fitch W, Vareed SK, Nair MG. Identification of metabolites in Withania sominfera fruits by liquid chromatography and high-resolution mass spectrometry Rapid Communications in Mass Spectrometry. 26: 1277-1290. PMID 22555921 DOI: 10.1002/Rcm.6221  0.342
2010 Fitch WL, Chen Y, Liu L, Paehler A, Young M. Application of modern drug metabolism structure determination tools and assays to the in vitro metabolism of imiloxan Drug Metabolism Letters. 4: 77-87. PMID 20446913 DOI: 10.2174/187231210791292753  0.301
2009 Fitch WL, Tran T, Young M, Liu L, Chen Y. Revisiting the metabolism of ketoconazole using accurate mass Drug Metabolism Letters. 3: 191-198. PMID 19799546 DOI: 10.2174/187231209789352085  0.337
2009 Wen B, Chen Y, Fitch WL. Metabolic activation of nevirapine in human liver microsomes: dehydrogenation and inactivation of cytochrome P450 3A4. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1557-62. PMID 19364830 DOI: 10.1124/Dmd.108.024851  0.307
2009 Wen B, Fitch WL. Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q-trap mass spectrometry. Journal of Mass Spectrometry : Jms. 44: 90-100. PMID 18720456 DOI: 10.1002/Jms.1475  0.377
2008 Wen B, Coe KJ, Rademacher P, Fitch WL, Monshouwer M, Nelson SD. Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH:cytochrome P450 reductase. Chemical Research in Toxicology. 21: 2393-406. PMID 19548358 DOI: 10.1021/Tx800281H  0.315
2007 Fitch WL, He L, Tu YP, Alexandrova L. Application of polarity switching in the identification of the metabolites of RO9237 Rapid Communications in Mass Spectrometry. 21: 1661-1668. PMID 17465015 DOI: 10.1002/Rcm.3009  0.345
2007 Chen Y, Monshouwer M, Fitch WL. Analytical tools and approaches for metabolite identification in early drug discovery Pharmaceutical Research. 24: 248-257. PMID 17048114 DOI: 10.1007/S11095-006-9162-7  0.349
2002 Fitch WL, Zhang JJ, Shah N, Ouchi GI, Wilgus RL, Muskal S. Software for automating analysis of encoded combinatorial libraries Combinatorial Chemistry and High Throughput Screening. 5: 531-543. PMID 12470266 DOI: 10.2174/1386207023330057  0.319
2000 Tang L, Fitch WL, Alexander MS, Dolan J. Expediting the method development and quality control of reversed-phase liquid chromatography electrospray ionization mass spectrometry for pharmaceutical analysis by using an LC/MS performance test mix Analytical Chemistry. 72: 5211-5218. PMID 11080866 DOI: 10.1021/Ac000651D  0.328
2000 Shah N, Gao M, Tsutsui K, Lu A, Davis J, Scheuerman R, Fitch WL, Wilgus RL. A novel approach to high-throughput quality control of parallel synthesis libraries Journal of Combinatorial Chemistry. 2: 453-460. PMID 11029170 DOI: 10.1021/Cc000011O  0.364
1998 Fitch WL. Analytical methods for quality control of combinatorial libraries Molecular Diversity. 4: 39-45. PMID 10320988 DOI: 10.1007/978-94-017-0735-0_5  0.312
1997 Gallop MA, Fitch WL. New methods for analyzing compounds on polymeric supports Current Opinion in Chemical Biology. 1: 94-100. PMID 9667832 DOI: 10.1016/S1367-5931(97)80114-7  0.348
1997 Fitch WL, Szardenings AK, Fujinari EM. Chemiluminescent nitrogen detection for HPLC: An important new tool in organic analytical chemistry Tetrahedron Letters. 38: 1689-1692. DOI: 10.1016/S0040-4039(97)00191-3  0.329
1979 Fitch WL, Anderson PJ, Smith DH. Isolation, identification and quantitation of urinary organic acids Journal of Chromatography B: Biomedical Sciences and Applications. 162: 249-259. PMID 528593 DOI: 10.1016/S0378-4347(00)81512-1  0.317
1978 Verheyden JPH, Richardson AC, Bhatt RS, Grant BD, Fitch WL, Moffatt JG. Chiral Syntheses of the Antibiotics Anisomycin and Pentenomycin from Carbohydrates Pure and Applied Chemistry. 50: 1363-1383. DOI: 10.1351/pac197850111363  0.468
1977 Smith DH, Achenbach M, Yeager WJ, Anderson PJ, Fitch WL, Rindfleisch TC. Quantitative comparison of combined gas chromatographic/mass spectrometric profiles of complex mixtures Analytical Chemistry. 49: 1623-1632. DOI: 10.1021/Ac50019A041  0.343
1975 FITCH WL, DOLINGER PM, DJERASSI C. ChemInform Abstract: ALKALOID STUDIES PART 68, NOVEL PIPERIDYL ALKALOIDS FROM LUPINUS FORMOSUS Chemischer Informationsdienst. 6: no-no. DOI: 10.1002/Chin.197503444  0.412
1974 Fitch WL, Dolinger PM, Djerassi C. Alkaloid studies. LXVIII. Novel piperidyl alkaloids from Lupinus formosus The Journal of Organic Chemistry. 39: 2974-2979. DOI: 10.1021/Jo00934A008  0.421
1974 Fitch WL, Djerassi C. Mass spectrometry in structural and stereochemical problems. CCXLIII. Functional group interaction. Unusual fragmentations of amides as exemplified by bipiperidyl alkaloids Journal of the American Chemical Society. 96: 4917-4927. DOI: 10.1021/Ja00822A032  0.405
1974 FITCH WL, DJERASSI C. ChemInform Abstract: MASS SPECTROMETRY IN STRUCTURAL AND STEREOCHEMICAL PROBLEMS PART 243, FUNCTIONAL GROUP INTERACTION, UNUSUAL FRAGMENTATIONS OF AMIDES AS EXEMPLIFIED BY BIPIPERIDYL ALKALOIDS Chemischer Informationsdienst. 5. DOI: 10.1002/Chin.197440090  0.411
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