Gary A. Churchill, Ph.D. - Publications

Affiliations: 
The Jackson Laboratory, Bar Harbor, ME, United States 

211 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Recla JM, Bubier JA, Gatti DM, Ryan JL, Long KH, Robledo RF, Glidden NC, Hou G, Churchill GA, Maser RS, Zhang ZW, Young EE, Chesler EJ, Bult CJ. Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response. Pain. PMID 30925521 DOI: 10.1097/j.pain.0000000000001571  0.48
2019 Broman KW, Gatti DM, Svenson KL, Sen Ś, Churchill GA. Cleaning Genotype Data from Diversity Outbred Mice. G3 (Bethesda, Md.). PMID 30877082 DOI: 10.1534/g3.119.400165  0.48
2018 Broman KW, Gatti DM, Simecek P, Furlotte NA, Prins P, Sen Ś, Yandell BS, Churchill GA. R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multi-parent Populations. Genetics. PMID 30591514 DOI: 10.1534/genetics.118.301595  0.48
2018 French JE, Gatti DM, Morgan DL, Kissling GE, Shockley KR, Knudsen GA, Shepard KG, Price HC, King D, Witt KL, Pedersen LC, Munger SC, Svenson KL, Churchill GA. Erratum: "Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity". Environmental Health Perspectives. 126: 069003. PMID 29957589 DOI: 10.1289/EHP3950  0.48
2018 Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MTG, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, ... ... Churchill GA, et al. Corrigendum: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. Nature Medicine. 24: 525. PMID 29634685 DOI: 10.1038/nm0418-525e  0.48
2018 Keller MP, Gatti DM, Schueler KL, Rabaglia ME, Stapleton DS, Simecek P, Vincent M, Allen S, Broman AT, Bacher R, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD. Genetic Drivers of Pancreatic Islet Function. Genetics. PMID 29567659 DOI: 10.1534/genetics.118.300864  0.48
2018 Raghupathy N, Choi K, Vincent MJ, Beane GL, Sheppard K, Munger SC, Korstanje R, Pardo-Manual de Villena F, Churchill GA, Valencia A. Hierarchical Analysis of RNA-Seq Reads Improves the Accuracy of Allele-specific Expression. Bioinformatics (Oxford, England). PMID 29444201 DOI: 10.1093/bioinformatics/bty078  0.48
2017 Tyler AL, Ji B, Gatti DM, Munger SC, Churchill GA, Svenson KL, Carter GW. Epistatic Networks Jointly Influence Phenotypes Related to Metabolic Disease and Gene Expression in Diversity Outbred Mice. Genetics. 206: 621-639. PMID 28592500 DOI: 10.1534/genetics.116.198051  0.48
2017 Morgan AP, Gatti DM, Najarian ML, Keane TM, Galante RJ, Pack AI, Mott R, Churchill GA, de Villena FP. Structural Variation Shapes the Landscape of Recombination in Mouse. Genetics. 206: 603-619. PMID 28592499 DOI: 10.1534/genetics.116.197988  0.48
2016 Winter JM, Gildea DE, Andreas JP, Gatti DM, Williams KA, Lee M, Hu Y, Zhang S, Mullikin JC, Wolfsberg TG, McDonnell SK, Fogarty ZC, Larson MC, French AJ, ... ... Churchill GA, et al. Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer. Cell Systems. PMID 27916600 DOI: 10.1016/j.cels.2016.10.018  0.48
2016 Chesler EJ, Gatti DM, Morgan AP, Strobel M, Trepanier L, Oberbeck D, McWeeney S, Hitzemann R, Ferris M, McMullan R, Clayshultle A, Bell TA, Pardo-Manuel de Villena F, Churchill GA. Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection. G3 (Bethesda, Md.). PMID 27694113 DOI: 10.1534/g3.116.035527  0.48
2016 Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SP. Defining the consequences of genetic variation on a proteome-wide scale. Nature. PMID 27309819 DOI: 10.1038/nature18270  0.48
2016 Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MT, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, ... ... Churchill GA, et al. Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. Nature Medicine. PMID 27270587 DOI: 10.1038/nm.4115  0.48
2016 Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, ... ... Churchill GA, et al. R2d2 drives selfish sweeps in the house mouse. Molecular Biology and Evolution. PMID 26882987 DOI: 10.1093/molbev/msw036  1
2016 Tyler AL, Donahue LR, Churchill GA, Carter GW. Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross. Plos Genetics. 12: e1005805. PMID 26828925 DOI: 10.1371/journal.pgen.1005805  1
2016 Gu T, Gatti DM, Srivastava A, Snyder EM, Raghupathy N, Simecek P, Svenson KL, Dotu I, Chuang JH, Keller MP, Attie AD, Braun RE, Churchill GA. Genetic Architectures of Quantitative Variation in RNA Editing Pathways. Genetics. 202: 787-98. PMID 26614740 DOI: 10.1534/genetics.115.179481  0.48
2015 Gralinski LE, Ferris MT, Aylor DL, Whitmore AC, Green R, Frieman MB, Deming D, Menachery VD, Miller DR, Buus RJ, Bell TA, Churchill GA, Threadgill DW, Katze MG, McMillan L, et al. Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross. Plos Genetics. 11: e1005504. PMID 26452100 DOI: 10.1371/journal.pgen.1005504  1
2015 Dell'Acqua M, Gatti DM, Pea G, Cattonaro F, Coppens F, Magris G, Hlaing AL, Aung HH, Nelissen H, Baute J, Frascaroli E, Churchill GA, Inzé D, Morgante M, Pè ME. Genetic properties of the MAGIC maize population: a new platform for high definition QTL mapping in Zea mays. Genome Biology. 16: 167. PMID 26357913 DOI: 10.1186/s13059-015-0716-z  1
2015 Rutledge H, Baran-Gale J, de Villena FP, Chesler EJ, Churchill GA, Sethupathy P, Kelada SN. Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population. Bmc Genomics. 16: 633. PMID 26303911 DOI: 10.1186/s12864-015-1732-9  1
2015 Rau CD, Parks B, Wang Y, Eskin E, Simecek P, Churchill GA, Lusis AJ. High Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda, Md.). PMID 26224782 DOI: 10.1534/g3.115.020784  1
2015 Simecek P, Churchill GA, Yang H, Rowe LB, Herberg L, Serreze DV, Leiter EH. Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice. G3 (Bethesda, Md.). 5: 771-5. PMID 25740934 DOI: 10.1534/g3.115.017046  1
2015 Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, ... ... Churchill GA, et al. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. Plos Genetics. 11: e1004850. PMID 25679959 DOI: 10.1371/journal.pgen.1004850  1
2015 Church RJ, Gatti DM, Urban TJ, Long N, Yang X, Shi Q, Eaddy JS, Mosedale M, Ballard S, Churchill GA, Navarro V, Watkins PB, Threadgill DW, Harrill AH. Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 76: 19-26. PMID 25446466 DOI: 10.1016/j.fct.2014.11.008  1
2015 French JE, Gatti DM, Morgan DL, Kissling GE, Shockley KR, Knudsen GA, Shepard KG, Price HC, King D, Witt KL, Pedersen LC, Munger SC, Svenson KL, Churchill GA. Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity. Environmental Health Perspectives. 123: 237-45. PMID 25376053 DOI: 10.1289/ehp.1408202  1
2015 Yuan R, Gatti DM, Krier R, Malay E, Schultz D, Peters LL, Churchill GA, Harrison DE, Paigen B. Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 817-26. PMID 25070661 DOI: 10.1093/gerona/glu114  1
2014 Bogue MA, Peters LL, Paigen B, Korstanje R, Yuan R, Ackert-Bicknell C, Grubb SC, Churchill GA, Chesler EJ. Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25533306 DOI: 10.1093/gerona/glu223  1
2014 Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA. Quantitative trait locus mapping methods for diversity outbred mice. G3 (Bethesda, Md.). 4: 1623-33. PMID 25237114 DOI: 10.1534/g3.114.013748  1
2014 Munger SC, Raghupathy N, Choi K, Simons AK, Gatti DM, Hinerfeld DA, Svenson KL, Keller MP, Attie AD, Hibbs MA, Graber JH, Chesler EJ, Churchill GA. RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations. Genetics. 198: 59-73. PMID 25236449 DOI: 10.1534/genetics.114.165886  0.48
2014 Rutledge H, Aylor DL, Carpenter DE, Peck BC, Chines P, Ostrowski LE, Chesler EJ, Churchill GA, de Villena FP, Kelada SN. Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in murine lung. Genetics. 198: 735-45. PMID 25114278 DOI: 10.1534/genetics.114.168138  1
2014 Yu W, Ackert-Bicknell C, Larigakis JD, MacIver B, Steers WD, Churchill GA, Hill WG, Zeidel ML. Spontaneous voiding by mice reveals strain-specific lower urinary tract function to be a quantitative genetic trait. American Journal of Physiology. Renal Physiology. 306: F1296-307. PMID 24717733 DOI: 10.1152/ajprenal.00074.2014  1
2014 Recla JM, Robledo RF, Gatti DM, Bult CJ, Churchill GA, Chesler EJ. Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 25: 211-22. PMID 24700285 DOI: 10.1007/s00335-014-9508-0  1
2014 Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chesler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS. Integrative genetic analysis of allergic inflammation in the murine lung. American Journal of Respiratory Cell and Molecular Biology. 51: 436-45. PMID 24693920 DOI: 10.1165/rcmb.2013-0501OC  1
2014 Liu EY, Morgan AP, Chesler EJ, Wang W, Churchill GA, Pardo-Manuel de Villena F. High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline. Genetics. 197: 91-106. PMID 24578350 DOI: 10.1534/genetics.114.161653  1
2014 Churchill GA. Misleading results: Don't blame the mice Science. 343: 370. PMID 24458625 DOI: 10.1126/science.343.6169.370-a  1
2014 Churchill GA. When are results too good to be true? Genetics. 198: 447-448. DOI: 10.1534/genetics.114.169912  1
2013 Kumar V, Kim K, Joseph C, Kourrich S, Yoo SH, Huang HC, Vitaterna MH, de Villena FP, Churchill G, Bonci A, Takahashi JS. C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response. Science (New York, N.Y.). 342: 1508-12. PMID 24357318 DOI: 10.1126/science.1245503  1
2013 Brockmann GA, Schäfer N, Hesse C, Heise S, Neuschl C, Wagener A, Churchill GA, Li R. Relationship between obesity phenotypes and genetic determinants in a mouse model for juvenile obesity Physiological Genomics. 45: 817-826. PMID 23922126 DOI: 10.1152/physiolgenomics.00058.2013  1
2013 McClatchy S, McGann D, Gotwals R, Baskett A, Churchill G. Students as collaborators in systems biology research Science. 340: 1061-1062. PMID 23723228 DOI: 10.1126/science.1229906  1
2013 Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, ... ... Churchill GA, et al. Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. Plos Pathogens. 9: e1003196. PMID 23468633 DOI: 10.1371/journal.ppat.1003196  1
2013 Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, ... ... Churchill G, et al. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. Plos One. 8: e56179. PMID 23457522 DOI: 10.1371/journal.pone.0056179  1
2013 Logan RW, Robledo RF, Recla JM, Philip VM, Bubier JA, Jay JJ, Harwood C, Wilcox T, Gatti DM, Bult CJ, Churchill GA, Chesler EJ. High-precision genetic mapping of behavioral traits in the diversity outbred mouse population. Genes, Brain, and Behavior. 12: 424-37. PMID 23433259 DOI: 10.1111/gbb.12029  1
2012 Aljakna A, Choi S, Savage H, Hageman Blair R, Gu T, Svenson KL, Churchill GA, Hibbs M, Korstanje R. Pla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterol Plos One. 7. PMID 22912808 DOI: 10.1371/journal.pone.0043139  1
2012 Churchill GA, Gatti DM, Munger SC, Svenson KL. The Diversity Outbred mouse population Mammalian Genome. 23: 713-718. PMID 22892839 DOI: 10.1007/s00335-012-9414-2  1
2012 Thaisz J, Tsaih SW, Feng M, Philip VM, Zhang Y, Yanas L, Sheehan S, Xu L, Miller DR, Paigen B, Chesler EJ, Churchill GA, Dipetrillo K. Genetic analysis of albuminuria in collaborative cross and multiple mouse intercross populations. American Journal of Physiology. Renal Physiology. 303: F972-81. PMID 22859403 DOI: 10.1152/ajprenal.00690.2011  1
2012 Pajer K, Andrus BM, Gardner W, Lourie A, Strange B, Campo J, Bridge J, Blizinsky K, Dennis K, Vedell P, Churchill GA, Redei EE. Discovery of blood transcriptomic markers for depression in animal models and pilot validation in subjects with early-onset major depression. Translational Psychiatry. 2: e101. PMID 22832901 DOI: 10.1038/tp.2012.26  1
2012 Leduc MS, Blair RH, Verdugo RA, Tsaih SW, Walsh K, Churchill GA, Paigen B. Using bioinformatics and systems genetics to dissect HDL-cholesterol genetics in an MRL/MpJ x SM/J intercross. Journal of Lipid Research. 53: 1163-75. PMID 22498810 DOI: 10.1194/jlr.M025833  1
2012 Blair RH, Kliebenstein DJ, Churchill GA. What can causal networks tell us about metabolic pathways? Plos Computational Biology. 8: e1002458. PMID 22496633 DOI: 10.1371/journal.pcbi.1002458  1
2012 Phifer-Rixey M, Bonhomme F, Boursot P, Churchill GA, Piálek J, Tucker PK, Nachman MW. Adaptive evolution and effective population size in wild house mice. Molecular Biology and Evolution. 29: 2949-55. PMID 22490822 DOI: 10.1093/molbev/mss105  1
2012 Kelada SN, Aylor DL, Peck BC, Ryan JF, Tavarez U, Buus RJ, Miller DR, Chesler EJ, Threadgill DW, Churchill GA, Pardo-Manuel de Villena F, Collins FS. Genetic analysis of hematological parameters in incipient lines of the collaborative cross. G3 (Bethesda, Md.). 2: 157-65. PMID 22384394 DOI: 10.1534/g3.111.001776  1
2012 Wang JR, de Villena FP, Lawson HA, Cheverud JM, Churchill GA, McMillan L. Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny. Genetics. 190: 449-58. PMID 22345612 DOI: 10.1534/genetics.111.132381  1
2012 Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA. High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics. 190: 437-47. PMID 22345611 DOI: 10.1534/genetics.111.132597  1
2012 Lenarcic AB, Svenson KL, Churchill GA, Valdar W. General Bayesian approach to analyzing diallel crosses of inbred strains Genetics. 190: 413-435. PMID 22345610 DOI: 10.1534/genetics.111.132563  1
2012 Iraqi FA, Mahajne M, Salaymah Y, Sandovski H, Tayem H, Vered K, Balmer L, Hall M, Manship G, Morahan G, Pettit K, Scholten J, Tweedie K, Wallace A, Weerasekera L, ... ... Churchill GA, et al. The genome architecture of the collaborative cross mouse genetic reference population Genetics. 190: 389-401. PMID 22345608 DOI: 10.1534/genetics.111.132639  1
2012 Threadgill DW, Churchill GA. Ten years of the Collaborative Cross. Genetics. 190: 291-4. PMID 22345604 DOI: 10.1534/genetics.111.138032  1
2012 Didion JP, Yang H, Sheppard K, Fu CP, McMillan L, de Villena FP, Churchill GA. Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias. Bmc Genomics. 13: 34. PMID 22260749 DOI: 10.1186/1471-2164-13-34  1
2012 Andrus BM, Blizinsky K, Vedell PT, Dennis K, Shukla PK, Schaffer DJ, Radulovic J, Churchill GA, Redei EE. Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models. Molecular Psychiatry. 17: 49-61. PMID 21079605 DOI: 10.1038/mp.2010.119  1
2012 Threadgill DW, Churchill GA. Ten years of the collaborative cross G3: Genes, Genomes, Genetics. 2: 153-156. DOI: 10.1534/g3.111.001891  1
2012 Zhang W, Korstanje R, Thaisz J, Staedtler F, Harttman N, Xu L, Feng M, Yanas L, Yang H, Valdar W, Churchill GA, DiPetrillo K. Genome-wide association mapping of quantitative traits in outbred mice G3: Genes, Genomes, Genetics. 2: 167-174. DOI: 10.1534/g3.111.001792  1
2011 Aitman TJ, Boone C, Churchill GA, Hengartner MO, Mackay TF, Stemple DL. The future of model organisms in human disease research. Nature Reviews. Genetics. 12: 575-82. PMID 21765459 DOI: 10.1038/nrg3047  1
2011 Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Shaw GS, Shinpock S, ... ... Churchill GA, et al. Genetic analysis in the Collaborative Cross breeding population. Genome Research. 21: 1223-38. PMID 21734011 DOI: 10.1101/gr.113886.110  1
2011 Yang H, Wang JR, Didion JP, Buus RJ, Bell TA, Welsh CE, Bonhomme F, Yu AH, Nachman MW, Pialek J, Tucker P, Boursot P, McMillan L, Churchill GA, de Villena FP. Subspecific origin and haplotype diversity in the laboratory mouse. Nature Genetics. 43: 648-55. PMID 21623374 DOI: 10.1038/ng.847  1
2011 Leduc MS, Hageman RS, Verdugo RA, Tsaih SW, Walsh K, Churchill GA, Paigen B. Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice Journal of Lipid Research. 52: 1672-1682. PMID 21622629 DOI: 10.1194/jlr.M011130  1
2011 Vedell PT, Svenson KL, Churchill GA. Stochastic variation of transcript abundance in C57BL/6J mice. Bmc Genomics. 12: 167. PMID 21450099 DOI: 10.1186/1471-2164-12-167  0.48
2011 Mathes WF, Aylor DL, Miller DR, Churchill GA, Chesler EJ, de Villena FP, Threadgill DW, Pomp D. Architecture of energy balance traits in emerging lines of the Collaborative Cross. American Journal of Physiology. Endocrinology and Metabolism. 300: E1124-34. PMID 21427413 DOI: 10.1152/ajpendo.00707.2010  1
2011 Threadgill DW, Miller DR, Churchill GA, de Villena FPM. The collaborative cross: A recombinant inbred mouse population for the systems genetic era Ilar Journal. 52: 24-31. PMID 21411855  1
2011 Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, ... ... Churchill GA, et al. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Research. 21: 1213-22. PMID 21406540 DOI: 10.1101/gr.111310.110  1
2011 Hageman RS, Leduc MS, Korstanje R, Paigen B, Churchill GA. A Bayesian framework for inference of the genotype-phenotype map for segregating populations Genetics. 187: 1163-1170. PMID 21242536 DOI: 10.1534/genetics.110.123273  1
2011 Hageman RS, Leduc MS, Caputo CR, Tsaih SW, Churchill GA, Korstanje R. Uncovering genes and regulatory pathways related to urinary albumin excretion Journal of the American Society of Nephrology. 22: 73-81. PMID 21030601 DOI: 10.1681/ASN.2010050561  1
2011 Vedell PT, Svenson KL, Churchill GA. Stochastic variation of transcript abundance in C57BL/6J mice Bmc Genomics. 12. DOI: 10.1186/1471-2164-12-167  1
2010 Li Y, Tesson BM, Churchill GA, Jansen RC. Critical reasoning on causal inference in genome-wide linkage and association studies. Trends in Genetics : Tig. 26: 493-8. PMID 20951462 DOI: 10.1016/j.tig.2010.09.002  1
2010 Li RH, Churchill GA. Epistasis contributes to the genetic buffering of plasma HDL cholesterol in mice Physiological Genomics. 42: 228-234. PMID 20858711 DOI: 10.1152/physiolgenomics.00044.2010  1
2010 Peters LL, Shavit JA, Lambert AJ, Tsaih SW, Li Q, Su Z, Leduc MS, Paigen B, Churchill GA, Ginsburg D, Brugnara C. Sequence variation at multiple loci influences red cell hemoglobin concentration. Blood. 116: e139-49. PMID 20833975 DOI: 10.1182/blood-2010-05-283879  1
2010 Woo YH, Walker M, Churchill GA. Coordinated Expression Domains in Mammalian Genomes Plos One. 5. PMID 20805879 DOI: 10.1371/journal.pone.0012158  1
2010 Leduc MS, Hageman RS, Meng Q, Verdugo RA, Tsaih SW, Churchill GA, Paigen B, Yuan R. Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains Aging Cell. 9: 823-836. PMID 20735370 DOI: 10.1111/j.1474-9726.2010.00612.x  1
2010 Hutchins LN, Ding Y, Szatkiewicz JP, Von Smith R, Yang H, de Villena FPM, Churchill GA, Graber JH. CGDSNPdb: a database resource for error-checked and imputed mouse SNPs. Database : the Journal of Biological Databases and Curation. 2010: baq008. PMID 20624716  1
2010 Hageman RS, Wagener A, Hantschel C, Svenson KL, Churchill GA, Brockmann GA. High-fat diet leads to tissue-specific changes reflecting risk factors for diseases in DBA/2J mice Physiological Genomics. 42: 55-66. PMID 20215417 DOI: 10.1152/physiolgenomics.00072.2009  1
2010 Ackert-Bicknell CL, Karasik D, Li Q, Smith RV, Hsu YH, Churchill GA, Paigen BJ, Tsaih SW. Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map Journal of Bone and Mineral Research. 25: 1808-1820. PMID 20200990 DOI: 10.1002/jbmr.72  1
2009 Smith R, Sheppard K, DiPetrillo K, Churchill G. Quantitative trait locus analysis using J/qtl. Methods in Molecular Biology (Clifton, N.J.). 573: 175-88. PMID 19763928 DOI: 10.1007/978-1-60761-247-6_10  1
2009 Solberg Woods LC, Ahmadiyeh N, Baum A, Shimomura K, Li Q, Steiner DF, Turek FW, Takahashi JS, Churchill GA, Redei EE. Identification of genetic loci involved in diabetes using a rat model of depression. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 486-97. PMID 19697080 DOI: 10.1007/s00335-009-9211-8  1
2009 Shockley KR, Witmer D, Burgess-Herbert SL, Paigen B, Churchill GA. Effects of atherogenic diet on hepatic gene expression across mouse strains Physiological Genomics. 39: 172-182. PMID 19671657 DOI: 10.1152/physiolgenomics.90350.2008  1
2009 Yang H, Ding Y, Hutchins LN, Szatkiewicz J, Bell TA, Paigen BJ, Graber JH, de Villena FPM, Churchill GA. A customized and versatile high-density genotyping array for the mouse Nature Methods. 6: 663-666. PMID 19668205 DOI: 10.1038/nmeth.1359  1
2009 Feng M, Deerhake ME, Keating R, Thaisz J, Xu L, Tsaih SW, Smith R, Ishige T, Sugiyama F, Churchill GA, DiPetrillo K. Genetic analysis of blood pressure in 8 mouse intercross populations Hypertension. 54: 802-809. PMID 19652078 DOI: 10.1161/HYPERTENSIONAHA.109.134569  1
2009 Rodriguez MR, Lundgren A, Sabastian P, Li Q, Churchill G, Brown MG. A Cmv2 QTL on chromosome X affects MCMV resistance in New Zealand male mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 414-23. PMID 19641964 DOI: 10.1007/s00335-009-9203-8  1
2009 Yuan R, Tsaih SW, Petkova SB, de Evsikova CM, Xing S, Marion MA, Bogue MA, Mills KD, Peters LL, Bult CJ, Rosen CJ, Sundberg JP, Harrison DE, Churchill GA, Paigen B. Aging in inbred strains of mice: Study design and interim report on median lifespans and circulating IGF1 levels Aging Cell. 8: 277-287. PMID 19627267 DOI: 10.1111/j.1474-9726.2009.00478.x  1
2009 Cox A, Ackert-Bicknell CL, Dumont BL, Ding Y, Bell JT, Brockmann GA, Wergedal JE, Bult C, Paigen B, Flint J, Tsaih SW, Churchill GA, Broman KW. A new standard genetic map for the laboratory mouse. Genetics. 182: 1335-44. PMID 19535546 DOI: 10.1534/genetics.109.105486  1
2009 Su Z, Ishimori N, Chen Y, Leiter EH, Churchill GA, Paigen B, Stylianou IM. Four additional mouse crosses improve the lipid QTL landscape and identify lipg as a QTL gene Journal of Lipid Research. 50: 2083-2094. PMID 19436067 DOI: 10.1194/jlr.M900076-JLR200  1
2009 Mackiewicz M, Zimmerman JE, Shockley KR, Churchill GA, Pack AI. What are microarrays teaching us about sleep? Trends in Molecular Medicine. 15: 79-87. PMID 19162550 DOI: 10.1016/j.molmed.2008.12.002  1
2009 Brockmann GA, Tsaih SW, Neuschl C, Churchill GA, Li R. Genetic factors contributing to obesity and body weight can act through mechanisms affecting muscle weight, fat weight, or both Physiological Genomics. 36: 114-126. PMID 18984673 DOI: 10.1152/physiolgenomics.90277.2008  1
2009 Ackert-Bicknell CL, Shockley KR, Horton LG, Lecka-Czernik B, Churchill GA, Rosen CJ. Strain-specific effects of rosiglitazone on bone mass, body composition, and serum insulin-like growth factor-I Endocrinology. 150: 1330-1340. DOI: 10.1210/en.2008-0936  1
2009 Llmas B, Verdugo RA, Churchill GA, Deschepper CF. Chromosome Y variants from different inbred mouse strains are linked to differences in the morphologic and molecular responses of cardiac cells to postpubertal testosterone Bmc Genomics. 10. DOI: 10.1186/1471-2164-10-150  1
2009 Shockley KR, Lazarenko OP, Czernik PJ, Rosen CJ, Churchill GA, Lecka-Czernik B. PPARγ2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells Journal of Cellular Biochemistry. 106: 232-246. DOI: 10.1002/jcb.21994  1
2008 Bailey JS, Grabowski-Boase L, Steffy BM, Wiltshire T, Churchill GA, Tarantino LM. Identification of quantitative trait loci for locomotor activation and anxiety using closely related inbred strains. Genes, Brain, and Behavior. 7: 761-9. PMID 19130624 DOI: 10.1111/j.1601-183X.2008.00415.x  1
2008 Yang H, Harrington CA, Vartanian K, Coldren CD, Hall R, Churchill GA. Randomization in laboratory procedure is key to obtaining reproducible microarray results Plos One. 3. PMID 19009020 DOI: 10.1371/journal.pone.0003724  1
2008 Chesler EJ, Miller DR, Branstetter LR, Galloway LD, Jackson BL, Philip VM, Voy BH, Culiat CT, Threadgill DW, Williams RW, Churchill GA, Johnson DK, Manly KF. The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 382-9. PMID 18716833 DOI: 10.1007/s00335-008-9135-8  1
2008 Ackert-Bicknell CL, Demissie S, Marín de Evsikova C, Hsu YH, DeMambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, et al. PPARG by dietary fat interaction influences bone mass in mice and humans Journal of Bone and Mineral Research. 23: 1398-1408. PMID 18707223 DOI: 10.1359/jbmr.080419  1
2008 Iraqi FA, Churchill G, Mott R. The Collaborative Cross, developing a resource for mammalian systems genetics: a status report of the Wellcome Trust cohort. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 379-81. PMID 18521666 DOI: 10.1007/s00335-008-9113-1  1
2008 Doorenbos C, Tsaih SW, Sheehan S, Ishimori N, Navis G, Churchill G, DiPetrillo K, Korstanje R. Quantitative trait loci for urinary albumin in crosses between C57BL/6J and A/J inbred mice in the presence and absence of Apoe Genetics. 179: 693-699. PMID 18493081 DOI: 10.1534/genetics.107.085142  1
2008 Ishimori N, Stylianou IM, Korstanje R, Marion MA, Li R, Donahue LR, Rosen CJ, Beamer WG, Paigen B, Churchill GA. Quantitative trait loci for BMD in an SM/J by NZB/BlNJ intercross population and identification of Trps1 as a probable candidate gene Journal of Bone and Mineral Research. 23: 1529-1537. PMID 18442308 DOI: 10.1359/jbmr.080414  1
2008 Szatkiewicz JP, Beane GL, Ding Y, Hutchins L, Pardo-Manuel De Villena F, Churchill GA. An imputed genotype resource for the laboratory mouse Mammalian Genome. 19: 199-208. PMID 18301946 DOI: 10.1007/s00335-008-9098-9  1
2008 Stylianou IM, Affourtit JP, Shockley KR, Wilpan RY, Abdi FA, Bhardwaj S, Rollins J, Churchill GA, Paigen B. Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification Genetics. 178: 1795-1805. PMID 18245842 DOI: 10.1534/genetics.107.081216  1
2008 Li R, Svenson KL, Donahue LRB, Peters LL, Churchill GA. Relationships of dietary fat, body composition, and bone mineral density in inbred mouse strain panels Physiological Genomics. 33: 26-32. PMID 18230669 DOI: 10.1152/physiolgenomics.00174.2007  1
2008 Churchill GA, Doerge RW. Naive application of permutation testing leads to inflated type I error rates Genetics. 178: 609-610. PMID 18202402 DOI: 10.1534/genetics.107.074609  1
2008 Kumar KG, Byerley LO, Volaufova J, Drucker DJ, Churchill GA, Li R, York B, Zuberi A, Richards BKS. Genetic variation in Glp1r expression influences the rate of gastric emptying in mice American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294: R362-R371. PMID 18077508 DOI: 10.1152/ajpregu.00640.2007  1
2008 Mrug M, Zhou J, Woo Y, Cui X, Szalai AJ, Novak J, Churchill GA, Guay-Woodford LM. Overexpression of innate immune response genes in a model of recessive polycystic kidney disease Kidney International. 73: 63-76. PMID 17960140 DOI: 10.1038/sj.ki.5002627  1
2008 Mrug M, Zhou J, Woo Y, Cui X, Szalai AJ, Novak J, Churchill GA, Guay-Woodford LM. Response to 'Overexpression of complement-component genes in Han:SPRD rats a model of polycystic kidney disease' Kidney International. 73: 1325. DOI: 10.1038/ki.2008.52  1
2008 Kerr MK, Churchill GA. Statistical design and the analysis of gene expression microarray data Genetics Research. 89: 509-514. DOI: 10.1017/S0016672308009713  1
2007 Schughart K, Churchill G. 6th annual meeting of the complex trait consortium Mammalian Genome. 18: 683-685. PMID 17906895 DOI: 10.1007/s00335-007-9057-x  1
2007 Kiernan AE, Li R, Hawes NL, Churchill GA, Gridley T. Genetic background modifies inner ear and eye phenotypes of Jag1 heterozygous mice Genetics. 177: 307-311. PMID 17890364 DOI: 10.1534/genetics.107.075960  1
2007 Sheehan S, Tsaih SW, King BL, Stanton C, Churchill GA, Paigen B, DiPetrillo K. Genetic analysis of albuminuria in a cross between C57BL/6J and DBA/2J mice American Journal of Physiology - Renal Physiology. 293: F1649-F1656. PMID 17804484 DOI: 10.1152/ajprenal.00233.2007  1
2007 Churchill GA. Recombinant inbred strain panels: A tool for systems genetics Physiological Genomics. 31: 174-175. PMID 17698925 DOI: 10.1152/physiolgenomics.00181.2007  1
2007 Mackiewicz M, Shockley KR, Romer MA, Galante RJ, Zimmerman JE, Naidoo N, Baldwin DA, Jensen ST, Churchill GA, Pack AI. Macromolecule biosynthesis: a key function of sleep. Physiological Genomics. 31: 441-57. PMID 17698924 DOI: 10.1152/physiolgenomics.00275.2006  1
2007 Yang H, Bell TA, Churchill GA, Pardo-Manuel De Villena F. On the subspecific origin of the laboratory mouse Nature Genetics. 39: 1100-1107. PMID 17660819 DOI: 10.1038/ng2087  1
2007 Nishihara E, Tsaih SW, Tsukahara C, Langley S, Sheehan S, DiPetrillo K, Kunita S, Yagami KI, Churchill GA, Paigen B, Sugiyama F. Quantitative trait loci associated with blood pressure of metabolic syndrome in the progeny of NZO/HILtJ x C3H/HeJ intercrosses Mammalian Genome. 18: 573-583. PMID 17641813 DOI: 10.1007/s00335-007-9033-5  1
2007 Davidson CE, Li Q, Churchill GA, Osborne LR, McDermid HE. Modifier locus for exencephaly in Cecr2 mutant mice is syntenic to the 10q25.3 region associated with neural tube defects in humans Physiological Genomics. 31: 244-251. PMID 17623803 DOI: 10.1152/physiolgenomics.00062.2007  1
2007 Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, Andrews PW, Beighton G, Bello PA, Benvenisty N, Berry LS, Bevan S, Blum B, Brooking J, Chen KG, Choo AB, ... Churchill GA, et al. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nature Biotechnology. 25: 803-16. PMID 17572666 DOI: 10.1038/nbt1318  1
2007 Petkov PM, Graber JH, Churchill GA, DiPetrillo K, King BL, Paigen K. Evidence of a large-scale functional organization of Mammalian chromosomes. Plos Biology. 5: e127; author reply e. PMID 17503963 DOI: 10.1371/journal.pgen.0010033  1
2007 Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, Hu Z, Rasmussen KE, Jones LP, Assefnia S, Chandrasekharan S, Backlund MG, Yin Y, Khramtsov AI, Bastein R, Quackenbush J, ... ... Churchill GA, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biology. 8: R76. PMID 17493263 DOI: 10.1186/gb-2007-8-5-r76  1
2007 Satagopan JM, Sen S, Churchill GA. Sequential quantitative trait locus mapping in experimental crosses Statistical Applications in Genetics and Molecular Biology. 6. PMID 17474878  1
2007 Sen S, Satagopan JM, Broman KW, Churchill GA. R/qtlDesign: Inbred line cross experimental design Mammalian Genome. 18: 87-93. PMID 17347894 DOI: 10.1007/s00335-006-0090-y  1
2007 Svenson KL, Von Smith R, Magnani PA, Suetin HR, Paigen B, Naggert JK, Li R, Churchill GA, Peters LL. Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations Journal of Applied Physiology. 102: 2369-2378. PMID 17317875 DOI: 10.1152/japplphysiol.01077.2006  1
2007 Peters LL, Robledo RF, Bult CJ, Churchill GA, Paigen BJ, Svenson KL. The mouse as a model for human biology: A resource guide for complex trait analysis Nature Reviews Genetics. 8: 58-69. PMID 17173058 DOI: 10.1038/nrg2025  1
2007 Lecka-Czernik B, Ackert-Bicknell C, Adamo ML, Marmolejos V, Churchill GA, Shockley KR, Reid IR, Grey A, Rosen CJ. Activation of peroxisome proliferator-activated receptor γ (PPARγ) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo Endocrinology. 148: 903-911. PMID 17122083 DOI: 10.1210/en.2006-1121  1
2007 Petkov PM, Graber JH, Churchill GA, DiPetrillo K, King BL, Paigen K. Evidence of a large- scale functional organization of mammalian chromosomes [1] Plos Biology. 5: 0984. DOI: 10.1371/journal.pbio.0050127  1
2007 Shockley KR, Rosen CJ, Churchill GA, Lecka-Czernik B. PPARγ2 regulates a molecular signature of marrow mesenchymal stem cells Ppar Research. DOI: 10.1155/2007/81219  1
2006 Broman KW, Sen S, Owens SE, Manichaikul A, Southard-Smith EM, Churchill GA. The X chromosome in quantitative trait locus mapping. Genetics. 174: 2151-8. PMID 17028340 DOI: 10.1534/genetics.106.061176  1
2006 Zimmerman JE, Rizzo W, Shockley KR, Raizen DM, Naidoo N, Mackiewicz M, Churchill GA, Pack AI. Multiple mechanisms limit the duration of wakefulness in Drosophila brain. Physiological Genomics. 27: 337-50. PMID 16954408 DOI: 10.1152/physiolgenomics.00030.2006  1
2006 Graber JH, Churchill GA, Dipetrillo KJ, King BL, Petkov PM, Paigen K. Patterns and mechanisms of genome organization in the mouse. Journal of Experimental Zoology. Part a, Comparative Experimental Biology. 305: 683-8. PMID 16902958 DOI: 10.1002/jez.a.322  1
2006 Solberg LC, Baum AE, Ahmadiyeh N, Shimomura K, Li R, Turek FW, Takahashi JS, Churchill GA, Redei EE. Genetic analysis of the stress-responsive adrenocortical axis. Physiological Genomics. 27: 362-9. PMID 16895972 DOI: 10.1152/physiolgenomics.00052.2006  1
2006 Cui X, Affourtit J, Shockley KR, Woo Y, Churchill GA. Inheritance patterns of transcript levels in F1 hybrid mice Genetics. 174: 627-637. PMID 16888332 DOI: 10.1534/genetics.106.060251  1
2006 Wergedal JE, Ackert-Bicknell CL, Tsaih SW, Sheng MH, Li R, Mohan S, Beamer WG, Churchill GA, Baylink DJ. Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 1256-66. PMID 16869724 DOI: 10.1359/jbmr.060510  1
2006 Li R, Tsaih SW, Shockley K, Stylianou IM, Wergedal J, Paigen B, Churchill GA. Structural model analysis of multiple quantitative traits. Plos Genetics. 2: e114. PMID 16848643 DOI: 10.1371/journal.pgen.0020114  1
2006 Shockley KR, Churchill GA. Gene expression analysis of mouse chromosome substitution strains. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 598-614. PMID 16783641 DOI: 10.1007/s00335-005-0176-y  1
2006 Churchill GA. The genetics of gene expression. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 465. PMID 16783627 DOI: 10.1007/s00335-006-1100-9  1
2006 Wittenburg H, Lyons MA, Li R, Kurtz U, Wang X, Mössner J, Churchill GA, Carey MC, Paigen B. QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains. Journal of Lipid Research. 47: 1780-90. PMID 16685081 DOI: 10.1194/jlr.M500544-JLR200  1
2006 Peters LL, Lambert AJ, Zhang W, Churchill GA, Brugnara C, Platt OS. Quantitative trait loci for baseline erythroid traits. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 298-309. PMID 16596451 DOI: 10.1007/s00335-005-0147-3  1
2006 Baum AE, Solberg LC, Churchill GA, Ahmadiyeh N, Takahashi JS, Redei EE. Test- and behavior-specific genetic factors affect WKY hypoactivity in tests of emotionality. Behavioural Brain Research. 169: 220-30. PMID 16490266 DOI: 10.1016/j.bbr.2006.01.007  1
2006 Stylianou IM, Korstanje R, Li R, Sheehan S, Paigen B, Churchill GA. Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci Mammalian Genome. 17: 22-36. PMID 16416088 DOI: 10.1007/s00335-005-0091-2  1
2006 Ishimori N, Li R, Walsh KA, Korstanje R, Rollins JA, Petkov P, Pletcher MT, Wiltshire T, Donahue LR, Rosen CJ, Beamer WG, Churchill GA, Paigen B. Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 105-12. PMID 16355279 DOI: 10.1359/JBMR.050902  1
2006 Kerr KF, Leiter EH, Picard L, Churchill GA. Sources of variation in microarray experiments experimental design and the analysis of variance for microarrays Computational and Statistical Approaches to Genomics. 37-47. DOI: 10.1007/0-387-26288-1_3  1
2005 Peters LL, Zhang W, Lambert AJ, Brugnara C, Churchill GA, Platt OS. Quantitative trait loci for baseline white blood cell count, platelet count, and mean platelet volume. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 749-63. PMID 16261417 DOI: 10.1007/s00335-005-0063-6  1
2005 Beamer WG, Shultz KL, Donahue LR, Churchill GA, Sen S, Wergedal JR, Baylink DJ, Rosen CJ. Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3h/HeJ inbred strains of mice. (2001) Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research.. 20: 1701-1712; discussio. PMID 16220609  1
2005 Wittenburg H, Lyons MA, Li R, Kurtz U, Mössner J, Churchill GA, Carey MC, Paigen B. Association of a lithogenic Abcg5/Abcg8 allele on Chromosome 17 (Lith9) with cholesterol gallstone formation in PERA/EiJ mice Mammalian Genome. 16: 495-504. PMID 16151694 DOI: 10.1007/s00335-005-0006-2  1
2005 Tsaih SW, Lu L, Airey DC, Williams RW, Churchill GA. Quantitative trait mapping in a diallel cross of recombinant inbred lines. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 344-55. PMID 16104382 DOI: 10.1007/s00335-004-2466-1  1
2005 Bouma GJ, Albrecht KH, Washburn LL, Recknagel AK, Churchill GA, Eicher EM. Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells. Development (Cambridge, England). 132: 3045-54. PMID 15944188 DOI: 10.1242/dev.01890  1
2005 Yi N, Yandell BS, Churchill GA, Allison DB, Eisen EJ, Pomp D. Bayesian model selection for genome-wide epistatic quantitative trait loci analysis. Genetics. 170: 1333-44. PMID 15911579 DOI: 10.1534/genetics.104.040386  1
2005 Lyons MA, Korstanje R, Li R, Sheehan SM, Walsh KA, Rollins JA, Carey MC, Paigen B, Churchill GA. Single and interacting QTLs for cholesterol gallstones revealed in an intercross between mouse strains NZB and SM. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 152-63. PMID 15834632 DOI: 10.1007/s00335-004-2446-5  1
2005 Sen S, Satagopan JM, Churchill GA. Quantitative trait locus study design from an information perspective Genetics. 170: 447-464. PMID 15781700 DOI: 10.1534/genetics.104.038612  1
2005 Dorward AM, Shultz KL, Horton LG, Li R, Churchill GA, Beamer WG. Distal Chr 4 harbors a genetic locus (Gct1) fundamental for spontaneous ovarian granulosa cell tumorigenesis in a mouse model Cancer Research. 65: 1259-1264. PMID 15735010 DOI: 10.1158/0008-5472.CAN-04-2992  1
2005 Mrug M, Li R, Cui X, Schoeb TR, Churchill GA, Guay-Woodford LM. Kinesin family member 12 is a candidate polycystic kidney disease modifier in the cpk mouse. Journal of the American Society of Nephrology : Jasn. 16: 905-16. PMID 15728779 DOI: 10.1681/ASN.2004121083  1
2005 Ahmadiyeh N, Churchill GA, Solberg LC, Baum AE, Shimomura K, Takahashi JS, Redei EE. Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress. Behavior Genetics. 35: 189-98. PMID 15685431 DOI: 10.1007/s10519-004-1018-5  1
2005 Ackerman KG, Huang H, Grasemann H, Puma C, Singer JB, Hill AE, Lander E, Nadeau JH, Churchill GA, Drazen JM, Beier DR. Interacting genetic loci cause airway hyperresponsiveness. Physiological Genomics. 21: 105-11. PMID 15657107 DOI: 10.1152/physiolgenomics.00267.2004  1
2005 Li R, Lyons MA, Wittenburg H, Paigen B, Churchill GA. Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping Genetics. 169: 1699-1709. PMID 15654110 DOI: 10.1534/genetics.104.033993  1
2005 Cui X, Hwang JT, Qiu J, Blades NJ, Churchill GA. Improved statistical tests for differential gene expression by shrinking variance components estimates. Biostatistics (Oxford, England). 6: 59-75. PMID 15618528 DOI: 10.1093/biostatistics/kxh018  1
2004 Mikaelian I, Blades N, Churchill GA, Fancher K, Knowles BB, Eppig JT, Sundberg JP. Proteotypic classification of spontaneous and transgenic mammary neoplasms. Breast Cancer Research : Bcr. 6: R668-79. PMID 15535849 DOI: 10.1186/bcr930  1
2004 Korstanje R, Eriksson P, Samnegård A, Olsson PG, Forsman-Semb K, Sen S, Churchill GA, Rollins J, Harris S, Hamsten A, Paigen B. Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans Atherosclerosis. 177: 443-450. PMID 15530921 DOI: 10.1016/j.atherosclerosis.2004.08.006  1
2004 Solberg LC, Baum AE, Ahmadiyeh N, Shimomura K, Li R, Turek FW, Churchill GA, Takahashi JS, Redei EE. Sex- and lineage-specific inheritance of depression-like behavior in the rat. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 648-62. PMID 15457344 DOI: 10.1007/s00335-004-2326-z  1
2004 Churchill GA. Using ANOVA to analyze microarray data Biotechniques. 37: 173-177. PMID 15335204  1
2004 Lobenhofer EK, Cui X, Bennett L, Cable PL, Merrick BA, Churchill GA, Afshari CA. Exploration of low-dose estrogen effects: Identification of No Observed Transcriptional Effect Level (NOTEL) Toxicologic Pathology. 32: 482-492. PMID 15223774 DOI: 10.1080/01926230490483324  1
2004 Ishimori N, Li R, Kelmenson PM, Korstanje R, Walsh KA, Churchill GA, Forsman-Semb K, Paigen B. Quantitative trait loci that determine plasma lipids and obesity in C57BL/6J and 129S1/SvImJ inbred mice Journal of Lipid Research. 45: 1624-1632. PMID 15210844 DOI: 10.1194/jlr.M400098-JLR200  1
2004 Grubb SC, Churchill GA, Bogue MA. A collaborative database of inbred mouse strain characteristics Bioinformatics. 20: 2857-2859. PMID 15130929 DOI: 10.1093/bioinformatics/bth299  1
2004 Peters LL, Swearingen RA, Andersen SG, Gwynn B, Lambert AJ, Li R, Lux SE, Churchill GA. Identification of quantitative trait loci that modify the severity of hereditary spherocytosis in wan, a new mouse model of band-3 deficiency. Blood. 103: 3233-40. PMID 15070709 DOI: 10.1182/blood-2003-08-2813  1
2004 Bouxsein ML, Uchiyama T, Rosen CJ, Shultz KL, Donahue LR, Turner CH, Sen S, Churchill GA, Müller R, Beamer WG. Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice Journal of Bone and Mineral Research. 19: 587-599. PMID 15005846 DOI: 10.1359/JBMR.0301255  1
2004 DiPetrillo K, Tsaih SW, Sheehan S, Johns C, Kelmenson P, Gavras H, Churchill GA, Paigen B. Genetic analysis of blood pressure in C3H/HeJ and SWR/J mice Physiological Genomics. 17: 215-220. PMID 14996992 DOI: 10.1152/physiolgenomics.00212.2003  1
2004 Lyons MA, Korstanje R, Li R, Walsh KA, Churchill GA, Carey MC, Paigen B. Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice Physiological Genomics. 17: 114-121. PMID 14872007 DOI: 10.1152/physiolgenomics.00168.2003  1
2004 Ishimori N, Li R, Kelmenson PM, Korstanje R, Walsh KA, Churchill GA, Forsman-Semb K, Paigen B. Quantitative Trait Loci Analysis for Plasma HDL-Cholesterol Concentrations and Atherosclerosis Susceptibility between Inbred Mouse Strains C57BL/6J and 129S1/SvImJ Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 161-166. PMID 14592847 DOI: 10.1161/01.ATV.0000104027.52895.D7  1
2004 Korstanje R, Albers JJ, Wolfbauer G, Li R, Tu AY, Churchill GA, Paigen BJ. Quantitative Trait Locus Mapping of Genes That Regulate Phospholipid Transfer Activity in SM/J and NZB/BINJ Inbred Mice Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 155-160. PMID 14592843 DOI: 10.1161/01.ATV.0000104241.44819.10  1
2004 Lyons MA, Wittenburg H, Li R, Walsh KA, Korstanje R, Churchill GA, Carey MC, Paigen B. Quantitative trait loci that determine lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and CAST/Ei inbred mice Physiological Genomics. 17: 60-68. DOI: 10.1152/physiolgenomics.00142.2003  1
2003 Ahmadiyeh N, Churchill GA, Shimomura K, Solberg LC, Takahashi JS, Redei EE. X-linked and lineage-dependent inheritance of coping responses to stress. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 748-57. PMID 14722724 DOI: 10.1007/s00335-003-2292-x  1
2003 Abiola O, Angel JM, Avner P, Bachmanov AA, Belknap JK, Bennett B, Blankenhorn EP, Blizard DA, Bolivar V, Brockmann GA, Buck KJ, Bureau JF, Casley WL, Chesler EJ, Cheverud JM, ... Churchill GA, et al. The nature and identification of quantitative trait loci: a community's view. Nature Reviews. Genetics. 4: 911-6. PMID 14634638 DOI: 10.1038/nrg1206  1
2003 Mathews CE, Graser RT, Bagley RJ, Caldwell JW, Li R, Churchill GA, Serreze DV, Leiter EH. Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress Immunogenetics. 55: 491-496. PMID 14513297 DOI: 10.1007/s00251-003-0603-8  1
2003 Wittenburg H, Lyons MA, Li R, Churchill GA, Carey MC, Paigen B. FXR and ABCGs/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice Gastroenterology. 125: 868-881. PMID 12949731 DOI: 10.1016/S0016-5085(03)01053-9  1
2003 Lyons MA, Wittenburg H, Li R, Walsh KA, Leonard MR, Churchill GA, Carey MC, Paigen B. New quantitative trait loci that contribute to cholesterol gallstone formation detected in an intercross of CAST/Ei and 129S1/SvImJ inbred mice Physiological Genomics. 14: 225-239. PMID 12837957  1
2003 Lyons MA, Wittenburg H, Li R, Walsh KA, Leonard MR, Korstanje R, Churchill GA, Carey MC, Paigen B. Lith6: A new QTL for cholesterol gallstones from an intercross of CAST/Ei and DBA/2J inbred mouse strains Journal of Lipid Research. 44: 1763-1771. PMID 12810825 DOI: 10.1194/jlr.M300149-JLR200  1
2003 Wang X, Le Roy I, Nicodeme E, Li R, Wagner R, Petros C, Churchill GA, Harris S, Darvasi A, Kirilovsky J, Roubertoux PL, Paigen B. Using advanced intercross lines for high-resolution mapping HDL cholesterol quantitative trait loci Genome Research. 13: 1654-1664. PMID 12805272 DOI: 10.1101/gr.1185803  1
2003 Broman KW, Wu H, Sen S, Churchill GA. R/qtl: QTL mapping in experimental crosses Bioinformatics. 19: 889-890. PMID 12724300 DOI: 10.1093/bioinformatics/btg112  1
2003 Cui X, Churchill GA. Statistical tests for differential expression in cDNA microarray experiments Genome Biology. 4. PMID 12702200 DOI: 10.1186/gb-2003-4-4-210  1
2003 Lyons MA, Wittenburg H, Li R, Walsh KA, Churchill GA, Carey MC, Paigen B. Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice Journal of Lipid Research. 44: 953-967. PMID 12588951 DOI: 10.1194/jlr.M300002-JLR200  1
2003 Smith Richards BK, Belton BN, Poole AC, Mancuso JJ, Churchill GA, Li R, Volaufova J, Zuberi A, York B. QTL analysis of self-selected macronutrient diet intake: Fat, carbohydrate, and total kilocalories Physiological Genomics. 11: 205-217.  1
2002 Churchill GA. Fundamentals of experimental design for cDNA microarrays Nature Genetics. 32: 490-495. PMID 12454643  1
2002 Mähler M, Most C, Schmidtke S, Sundberg JP, Li R, Hedrich HJ, Churchill GA. Genetics of colitis susceptibility in IL-10-deficient mice: Backcross versus F2 results contrasted by principal component analysis Genomics. 80: 274-282. PMID 12213197 DOI: 10.1006/geno.2002.6840  1
2002 Sugiyama F, Churchill GA, Li R, Libby LJ, Carver T, Yagami K, John SW, Paigen B. QTL associated with blood pressure, heart rate, and heart weight in CBA/CaJ and BALB/cJ mice. Physiological Genomics. 10: 5-12. PMID 12118100 DOI: 10.1152/physiolgenomics.00002.2002  1
2002 Pitman WA, Korstanje R, Churchill GA, Nicodeme E, Albers JJ, Cheung MC, Staton MA, Sampson SS, Harris S, Paigen B. Quantitative trait locus mapping of genes that regulate HDL cholesterol in SM/J and NZB/B1NJ inbred mice Physiological Genomics. 2002: 93-102. PMID 12006675  1
2002 Broman KW, Rowe LB, Churchill GA, Paigen K. Crossover interference in the mouse Genetics. 160: 1123-1131. PMID 11901128  1
2002 Sugiyama F, Churchill GA, Li R, Libby LJM, Carver T, Yagami KI, John SWM, Paigen B. QTL associated with blood pressure, heart rate, and heart weight in CBA/CaJ and BALB/cJ mice Physiological Genomics. 2002: 5-12.  1
2002 Wittenburg H, Lammert F, Wang DQH, Churchill GA, Li R, Bouchard G, Carey MC, Paigen B. Interacting QTLs for cholesterol gallstones and gallbladder mucin in AKR and SWR strains of mice Physiological Genomics. 2002: 67-77.  1
2002 Kerr MK, Afshari CA, Bennett L, Bushel P, Martinez J, Walker NJ, Churchill GA. Statistical analysis of a gene expression microarray experiment with replication Statistica Sinica. 12: 203-217.  1
2001 Churchill GA, Oliver B. Sex, flies and microarrays Nature Genetics. 29: 355-356. PMID 11726914 DOI: 10.1038/ng1201-355  1
2001 Farmer MA, Sundberg JP, Bristol IJ, Churchill GA, Li R, Elson CO, Leiter EH. A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 13820-5. PMID 11707574 DOI: 10.1073/pnas.241258698  1
2001 Sen S, Churchill GA. A statistical framework for quantitative trait mapping Genetics. 159: 371-387. PMID 11560912  1
2001 Kerr MK, Churchill GA. Bootstrapping cluster analysis: Assessing the reliability of conclusions from microarray experiments Proceedings of the National Academy of Sciences of the United States of America. 98: 8961-8965. PMID 11470909 DOI: 10.1073/pnas.161273698  1
2001 Kim JH, Sen. A, Avery CS, Simpson E, Chandler P, Nishina PM, Churchill GA, Naggert JK. Genetic analysis of a new mouse model for non-insulin-dependent diabetes Genomics. 74: 273-286. PMID 11414755 DOI: 10.1006/geno.2001.6569  1
2001 Kerr MK, Martin M, Churchill GA. Analysis of variance for gene expression microarray data Journal of Computational Biology. 7: 819-837. PMID 11382364 DOI: 10.1089/10665270050514954  1
2001 Shimomura K, Low-Zeddies SS, King DP, Steeves TD, Whiteley A, Kushla J, Zemenides PD, Lin A, Vitaterna MH, Churchill GA, Takahashi JS. Genome-wide epistatic interaction analysis reveals complex genetic determinants of circadian behavior in mice. Genome Research. 11: 959-80. PMID 11381025 DOI: 10.1101/gr.171601  1
2001 Reeb-Whitaker CK, Paigen B, Beamer WG, Bronson RT, Churchill GA, Schweitzer IB, Myers DD. The impact of reduced frequency of cage changes on the health of mice housed in ventilated cages Laboratory Animals. 35: 58-73. PMID 11201289 DOI: 10.1258/0023677011911381  1
2001 Sugiyama F, Churchill GA, Higgins DC, Johns C, Makaritsis KP, Gavras H, Paigen B. Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci. Genomics. 71: 70-7. PMID 11161799 DOI: 10.1006/geno.2000.6401  1
2000 Shpak M, Churchill GA. The information content of a character under a Markov model of evolution. Molecular Phylogenetics and Evolution. 17: 231-43. PMID 11083937 DOI: 10.1006/mpev.2000.0846  1
2000 Rosen CJ, Churchill GA, Donahue LR, Shultz KL, Burgess JK, Powell DR, Beamer WG. Mapping quantitative trait loci for serum insulin-like growth factor-1 levels in mice Bone. 27: 521-528. PMID 11033447 DOI: 10.1016/S8756-3282(00)00354-9  1
2000 Guay-Woodford LM, Wright CJ, Walz G, Churchill GA. Quantitative trait loci modulate renal cystic disease severity in the mouse bpk model. Journal of the American Society of Nephrology : Jasn. 11: 1253-60. PMID 10864581  1
1999 Beamer WG, Shultz KL, Churchill GA, Frankel WN, Baylink DJ, Rosen CJ, Donahue LR. Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice Mammalian Genome. 10: 1043-1049. PMID 10556421 DOI: 10.1007/s003359901159  1
1999 Churchill GA, Lazareva B. Bayesian restoration of a Hidden Markov chain with applications to DNA sequencing Journal of Computational Biology. 6: 261-277. PMID 10421527  1
1999 Ripol MI, Churchill GA, Da Silva JAG, Sorrells M. Statistical aspects of genetic mapping in autopolyploids Gene. 235: 31-41. PMID 10415330 DOI: 10.1016/S0378-1119(99)00218-8  1
1999 Mähler M, Bristol IJ, Sundberg JP, Churchill GA, Birkenmeier EH, Elson CO, Leiter EH. Genetic analysis of susceptibility to dextran sulfate sodium-induced colitis in mice Genomics. 55: 147-156. PMID 9933561 DOI: 10.1006/geno.1998.5636  1
1999 Blauth SL, Steffens JC, Churchill GA, Mutschler MA. Identification of QTLs controlling acylsugar fatty acid composition in an intraspecific population of Lycopersicon pennellii (Corr.) D'Arcy Theoretical and Applied Genetics. 99: 373-381. DOI: 10.1007/s001220051247  1
1999 Schultz TR, Churchill GA. The role of subjectivity in reconstructing ancestral character states: A Bayesian approach to unknown rates, states, and transformation asymmetries Systematic Biology. 48: 651-664.  1
1998 Beamer WG, Shultz KL, Tennent BJ, Nadeau JH, Churchill GA, Eicher EM. Multigenic and imprinting control of ovarian granulosa cell tumorigenesis in mice Cancer Research. 58: 3694-3699. PMID 9721880  1
1998 Blauth SL, Churchill GA, Mutschler MA. Identification of quantitative trait loci associated with acylsugar accumulation using intraspecific populations of the wild tomato, Lycopersicon pennellii Theoretical and Applied Genetics. 96: 458-467. DOI: 10.1007/s001220050762  1
1997 Simonsen KL, Churchill GA. A Markov chain model of coalescence with recombination Theoretical Population Biology. 52: 43-59. DOI: 10.1006/tpbi.1997.1307  1
1996 Nachman MW, Churchill GA. Heterogeneity in rates of recombination across the mouse genome Genetics. 142: 537-548. PMID 8852851  1
1996 Doerge RW, Churchill GA. Permutation tests for multiple loci affecting a quantitative character Genetics. 142: 285-294. PMID 8770605  1
1996 Felsenstein J, Churchill GA. A Hidden Markov Model approach to variation among sites in rate of evolution. Molecular Biology and Evolution. 13: 93-104. PMID 8583911  1
1996 Schultz TR, Cocroft RB, Churchill GA. The reconstruction of ancestral character states Evolution. 50: 504-511.  1
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