Jochen Herms, M.D. - Publications

Affiliations: 
2001- Neuropathology Ludwig-Maximilians-Universität München, München, Bayern, Germany 
 2011- Translational Brain Research German Center for Neurodegenerative Diseases 
Area:
Synaptic transmission, dendritic spines, Alzheimers Disease, Neuropathology, structural plasticity

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ruch F, Gnörich J, Wind K, Köhler M, Zatcepin A, Wiedemann T, Gildehaus FJ, Lindner S, Boening G, von Ungern-Sternberg B, Beyer L, Herms J, Bartenstein P, Brendel M, Eckenweber F. Validity and value of metabolic connectivity in mouse models of β-amyloid and tauopathy. Neuroimage. 286: 120513. PMID 38191101 DOI: 10.1016/j.neuroimage.2024.120513  0.578
2023 Bartos LM, Kirchleitner SV, Kolabas ZI, Quach S, Beck A, Lorenz J, Blobner J, Mueller SA, Ulukaya S, Hoeher L, Horvath I, Wind-Mark K, Holzgreve A, Ruf VC, Gold L, ... ... Herms J, et al. Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution. Science Advances. 9: eadi8986. PMID 37889970 DOI: 10.1126/sciadv.adi8986  0.515
2023 Weidner L, Lorenz J, Quach S, Braun FK, Rothhammer-Hampl T, Ammer LM, Vollmann-Zwerenz A, Bartos LM, Dekorsy FJ, Holzgreve A, Kirchleitner SV, Thon N, Greve T, Ruf V, Herms J, et al. Translocator protein (18kDA) (TSPO) marks mesenchymal glioblastoma cell populations characterized by elevated numbers of tumor-associated macrophages. Acta Neuropathologica Communications. 11: 147. PMID 37697350 DOI: 10.1186/s40478-023-01651-5  0.516
2023 Vogler L, Ballweg A, Bohr B, Briel N, Wind K, Antons M, Kunze LH, Gnörich J, Lindner S, Gildehaus FJ, Baumann K, Bartenstein P, Boening G, Ziegler SI, Levin J, ... ... Herms J, et al. Assessment of synaptic loss in mouse models of β-amyloid and tau pathology using [F]UCB-H PET imaging. Neuroimage. Clinical. 39: 103484. PMID 37541098 DOI: 10.1016/j.nicl.2023.103484  0.592
2023 Albert NL, Nelwan DV, Fleischmann DF, Quach S, von Rohr K, Kaiser L, Teske N, Unterrainer LM, Bartos LM, Ruf VC, Brendel M, Riemenschneider MJ, Wetzel C, Herms J, Rupprecht R, et al. Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 37536737 DOI: 10.2967/jnumed.122.265247  0.527
2023 Kunze LH, Ruch F, Biechele G, Eckenweber F, Wind-Mark K, Dinkel L, Feyen P, Bartenstein P, Ziegler S, Paeger L, Tahirovic S, Herms J, Brendel M. Long-Term Pioglitazone Treatment Has No Significant Impact on Microglial Activation and Tau Pathology in P301S Mice. International Journal of Molecular Sciences. 24. PMID 37373253 DOI: 10.3390/ijms241210106  0.573
2023 Koeglsperger T, Rumpf SL, Schließer P, Struebing FL, Brendel M, Levin J, Trenkwalder C, Höglinger GU, Herms J. Neuropathology of incidental Lewy body & prodromal Parkinson's disease. Molecular Neurodegeneration. 18: 32. PMID 37173733 DOI: 10.1186/s13024-023-00622-7  0.472
2023 Ballweg A, Klaus C, Vogler L, Katzdobler S, Wind K, Zatcepin A, Ziegler SI, Secgin B, Eckenweber F, Bohr B, Bernhardt A, Fietzek U, Rauchmann BS, Stoecklein S, Quach S, ... ... Herms J, et al. [F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data. Journal of Neuroinflammation. 20: 68. PMID 36906584 DOI: 10.1186/s12974-023-02749-2  0.584
2023 Gnörich J, Reifschneider A, Wind K, Zatcepin A, Kunte ST, Beumers P, Bartos LM, Wiedemann T, Grosch M, Xiang X, Fard MK, Ruch F, Werner G, Koehler M, Slemann L, ... ... Herms J, et al. Depletion and activation of microglia impact metabolic connectivity of the mouse brain. Journal of Neuroinflammation. 20: 47. PMID 36829182 DOI: 10.1186/s12974-023-02735-8  0.499
2022 Quach S, Holzgreve A, Kaiser L, Unterrainer M, Dekorsy FJ, Nelwan DV, Bartos LM, Kirchleitner SV, Weller J, Weidner L, Niyazi M, Ruf VC, Herms J, Stöcklein S, Wetzel C, et al. TSPO PET signal using [F]GE180 is associated with survival in recurrent gliomas. European Journal of Nuclear Medicine and Molecular Imaging. PMID 36329288 DOI: 10.1007/s00259-022-06006-1  0.519
2022 Blume T, Filser S, Sgobio C, Peters F, Neumann U, Shimshek D, Saito T, Saido TC, Brendel M, Herms J. β-secretase inhibition prevents structural spine plasticity deficits in mice. Frontiers in Aging Neuroscience. 14: 909586. PMID 35936777 DOI: 10.3389/fnagi.2022.909586  0.545
2022 Blume T, Deussing M, Biechele G, Peters F, Zott B, Schmidt C, Franzmeier N, Wind K, Eckenweber F, Sacher C, Shi Y, Ochs K, Kleinberger G, Xiang X, Focke C, ... ... Herms J, et al. Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition. Frontiers in Aging Neuroscience. 14: 854031. PMID 35431893 DOI: 10.3389/fnagi.2022.854031  0.595
2022 Messerschmidt K, Barthel H, Brendel M, Scherlach C, Hoffmann KT, Rauchmann BS, Rullmann M, Marek K, Villemagne VL, Rumpf JJ, Saur D, Schroeter ML, Schildan A, Patt M, Beyer L, ... ... Herms J, et al. F-PI-2620 Tau PET Improves the Imaging Diagnosis of Progressive Supranuclear Palsy. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 35422444 DOI: 10.2967/jnumed.121.262854  0.558
2022 Franzmeier N, Brendel M, Beyer L, Slemann L, Kovacs GG, Arzberger T, Kurz C, Respondek G, Lukic MJ, Biel D, Rubinski A, Frontzkowski L, Hummel S, Müller A, Finze A, ... ... Herms J, et al. Tau deposition patterns are associated with functional connectivity in primary tauopathies. Nature Communications. 13: 1362. PMID 35292638 DOI: 10.1038/s41467-022-28896-3  0.548
2022 Shi Y, Cui M, Ochs K, Brendel M, Strübing FL, Briel N, Eckenweber F, Zou C, Banati RB, Liu GJ, Middleton RJ, Rupprecht R, Rudolph U, Zeilhofer HU, Rammes G, ... Herms J, et al. Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO). Nature Neuroscience. 25: 317-329. PMID 35228700 DOI: 10.1038/s41593-022-01013-9  0.468
2021 Xiang X, Wind K, Wiedemann T, Blume T, Shi Y, Briel N, Beyer L, Biechele G, Eckenweber F, Zatcepin A, Lammich S, Ribicic S, Tahirovic S, Willem M, Deussing M, ... ... Herms J, et al. Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases. Science Translational Medicine. 13: eabe5640. PMID 34644146 DOI: 10.1126/scitranslmed.abe5640  0.516
2021 Biechele G, Blume T, Deussing M, Zott B, Shi Y, Xiang X, Franzmeier N, Kleinberger G, Peters F, Ochs K, Focke C, Sacher C, Wind K, Schmidt C, Lindner S, ... ... Herms J, et al. Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation. Theranostics. 11: 8964-8976. PMID 34522221 DOI: 10.7150/thno.64022  0.584
2021 Willroider M, Roeber S, Horn AKE, Arzberger T, Scheifele M, Respondek G, Sabri O, Barthel H, Patt M, Mishchenko O, Schildan A, Mueller A, Koglin N, Stephens A, Levin J, ... ... Herms J, et al. Superiority of Formalin-Fixed Paraffin-Embedded Brain Tissue for Assessment of Progressive Supranuclear Palsy Tau Pathology With [ F]PI-2620. Frontiers in Neurology. 12: 684523. PMID 34276540 DOI: 10.3389/fneur.2021.684523  0.543
2021 Mittlmeier LM, Suchorska B, Ruf V, Holzgreve A, Brendel M, Herms J, Bartenstein P, Tonn JC, Unterrainer M, Albert NL. F-FET PET Uptake Characteristics of Long-Term IDH-Wildtype Diffuse Glioma Survivors. Cancers. 13. PMID 34202726 DOI: 10.3390/cancers13133163  0.52
2021 Song M, Beyer L, Kaiser L, Barthel H, van Eimeren T, Marek K, Nitschmann A, Scheifele M, Palleis C, Respondek G, Kern M, Biechele G, Hammes J, Bischof G, Barbe M, ... ... Herms J, et al. Binding characteristics of [F]PI-2620 distinguish the clinically predicted tau isoform in different tauopathies by PET. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211018904. PMID 34044665 DOI: 10.1177/0271678X211018904  0.484
2021 Biechele G, Sebastian Monasor L, Wind K, Blume T, Parhizkar S, Arzberger T, Sacher C, Beyer L, Eckenweber F, Gildehaus FJ, von Ungern-Sternberg B, Willem M, Bartenstein P, Cumming P, Rominger A, ... Herms J, et al. Glitter in the Darkness? Non-fibrillar β-amyloid Plaque Components Significantly Impact the β-amyloid PET Signal in Mouse Models of Alzheimer's Disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 34016733 DOI: 10.2967/jnumed.120.261858  0.606
2021 Unterrainer M, Ruf V, von Rohr K, Suchorska B, Mittlmeier LM, Beyer L, Brendel M, Wenter V, Kunz WG, Bartenstein P, Herms J, Niyazi M, Tonn JC, Albert NL. TERT-Promoter Mutational Status in Glioblastoma - Is There an Association With Amino Acid Uptake on Dynamic F-FET PET? Frontiers in Oncology. 11: 645316. PMID 33996563 DOI: 10.3389/fonc.2021.645316  0.522
2020 Biechele G, Wind K, Blume T, Sacher C, Beyer L, Eckenweber F, Franzmeier N, Ewers M, Zott B, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Tahirovic S, Willem M, Bartenstein P, ... ... Herms J, et al. Microglial Activation in the Right Amygdala-Entorhinal-Hippocampal Complex is Associated with Preserved Spatial Learning in App mice. Neuroimage. 117707. PMID 33385560 DOI: 10.1016/j.neuroimage.2020.117707  0.569
2020 Biechele G, Franzmeier N, Blume T, Ewers M, Luque JM, Eckenweber F, Sacher C, Beyer L, Ruch-Rubinstein F, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Cumming P, Bartenstein P, Rominger A, ... ... Herms J, et al. Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases. Journal of Neuroinflammation. 17: 374. PMID 33317543 DOI: 10.1186/s12974-020-02046-2  0.56
2020 Palleis C, Sauerbeck J, Beyer L, Harris S, Schmitt J, Morenas-Rodriguez E, Finze A, Nitschmann A, Ruch-Rubinstein F, Eckenweber F, Biechele G, Blume T, Shi Y, Weidinger E, Prix C, ... ... Herms J, et al. In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33245166 DOI: 10.1002/mds.28395  0.461
2020 Brendel M, Barthel H, van Eimeren T, Marek K, Beyer L, Song M, Palleis C, Gehmeyr M, Fietzek U, Respondek G, Sauerbeck J, Nitschmann A, Zach C, Hammes J, Barbe MT, ... ... Herms J, et al. Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy. Jama Neurology. 77: 1408-1419. PMID 33165511 DOI: 10.1001/Jamaneurol.2020.2526  0.561
2020 Ewers M, Biechele G, Suárez-Calvet M, Sacher C, Blume T, Morenas-Rodriguez E, Deming Y, Piccio L, Cruchaga C, Kleinberger G, Shaw L, Trojanowski JQ, Herms J, Dichgans M, et al. Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation. Embo Molecular Medicine. e12308. PMID 32790063 DOI: 10.15252/Emmm.202012308  0.636
2020 Eckenweber F, Medina-Luque J, Blume T, Sacher C, Biechele G, Wind K, Deussing M, Briel N, Lindner S, Boening G, von Ungern-Sternberg B, Unterrainer M, Albert NL, Zwergal A, Levin J, ... ... Herms J, et al. Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning. Journal of Neuroinflammation. 17: 208. PMID 32660586 DOI: 10.1186/S12974-020-01883-5  0.607
2020 Sebastian Monasor L, Müller SA, Colombo AV, Tanrioever G, König J, Roth S, Liesz A, Berghofer A, Piechotta A, Prestel M, Saito T, Saido TC, Herms J, Willem M, Haass C, et al. Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models. Elife. 9. PMID 32510331 DOI: 10.7554/Elife.54083  0.407
2020 Sacher C, Blume T, Beyer L, Biechele G, Sauerbeck J, Eckenweber F, Deussing M, Focke C, Parhizkar S, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Baumann K, Tahirovic S, Kleinberger G, ... ... Herms J, et al. Asymmetry of fibrillar plaque burden in amyloid mouse models. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 32414948 DOI: 10.2967/Jnumed.120.242750  0.637
2020 Beyer L, Nitschmann A, Barthel H, van Eimeren T, Unterrainer M, Sauerbeck J, Marek K, Song M, Palleis C, Respondek G, Hammes J, Barbe MT, Onur Ö, Jessen F, Saur D, ... ... Herms J, et al. Early-phase [F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32318783 DOI: 10.1007/S00259-020-04788-W  0.611
2020 Monasor LS, Müller SA, Colombo AV, Tanrioever G, König J, Roth S, Liesz A, Berghofer A, Piechotta A, Prestel M, Saito T, Saido TC, Herms J, Willem M, Haass C, et al. Author response: Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models Elife. DOI: 10.7554/Elife.54083.Sa2  0.357
2019 Peters F, Salihoglu H, Pratsch K, Herzog E, Pigoni M, Sgobio C, Lichtenthaler SF, Neumann U, Herms J. Tau deletion reduces plaque-associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease. The Embo Journal. e2019102345. PMID 31701556 DOI: 10.15252/Embj.2019102345  0.397
2019 Unterrainer M, Ruf V, Cyran CC, Brendel M, Thon N, Herms J, Schüller U, Tonn JC, Bartenstein P, Albert NL. Identification of Distant Metastases From Recurrent Gliosarcoma Using Whole-Body 18F-FDG PET/CT. Clinical Nuclear Medicine. 44: 923-924. PMID 31584491 DOI: 10.1097/Rlu.0000000000002790  0.575
2019 Unterrainer M, Fleischmann DF, Vettermann F, Ruf V, Kaiser L, Nelwan D, Lindner S, Brendel M, Wenter V, Stöcklein S, Herms J, Milenkovic VM, Rupprecht R, Tonn JC, Belka C, et al. TSPO PET, tumour grading and molecular genetics in histologically verified glioma: a correlative F-GE-180 PET study. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31486876 DOI: 10.1007/S00259-019-04491-5  0.589
2019 Blumenstock S, Angelo MF, Peters F, Dorostkar MM, Ruf VC, Luckner M, Crux S, Slapakova L, Arzberger T, Claverol S, Herzog E, Herms J. Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy. Acta Neuropathologica. PMID 31451907 DOI: 10.1007/S00401-019-02063-3  0.333
2019 Vettermann F, Suchorska B, Unterrainer M, Nelwan D, Forbrig R, Ruf V, Wenter V, Kreth FW, Herms J, Bartenstein P, Tonn JC, Albert NL. Non-invasive prediction of IDH-wildtype genotype in gliomas using dynamic F-FET PET. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31410540 DOI: 10.1007/S00259-019-04477-3  0.341
2019 Brendel M, Deussing M, Blume T, Kaiser L, Probst F, Overhoff F, Peters F, von Ungern-Sternberg B, Ryazanov S, Leonov A, Griesinger C, Zwergal A, Levin J, Bartenstein P, Yakushev I, ... ... Herms J, et al. Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau. Alzheimer's Research & Therapy. 11: 67. PMID 31370885 DOI: 10.1186/S13195-019-0522-Z  0.636
2019 Sacher C, Blume T, Beyer L, Peters F, Eckenweber F, Sgobio C, Deussing M, Albert NL, Unterrainer M, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Brzak I, Neumann U, Saito T, ... ... Herms J, et al. Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second Generation Amyloid-beta Mouse Model. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 31302633 DOI: 10.2967/Jnumed.119.227322  0.631
2019 Marinković P, Blumenstock S, Goltstein PM, Korzhova V, Peters F, Knebl A, Herms J. In vivo imaging reveals reduced activity of neuronal circuits in a mouse tauopathy model. Brain : a Journal of Neurology. PMID 30847469 DOI: 10.1093/Brain/Awz035  0.37
2019 Yin C, Ackermann S, Ma Z, Mohanta SK, Zhang C, Li Y, Nietzsche S, Westermann M, Peng L, Hu D, Bontha SV, Srikakulapu P, Beer M, Megens RTA, Steffens S, ... ... Herms J, et al. ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nature Medicine. PMID 30692699 DOI: 10.1038/S41591-018-0336-8  0.35
2019 Montagna E, Crux S, Luckner M, Herber J, Colombo AV, Marinković P, Tahirovic S, Lichtenthaler SF, Wanner G, Müller UC, Sgobio C, Herms J. In vivo Ca imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria. Glia. PMID 30667091 DOI: 10.1002/Glia.23584  0.319
2019 Parhizkar S, Arzberger T, Brendel M, Kleinberger G, Deussing M, Focke C, Nuscher B, Xiong M, Ghasemigharagoz A, Katzmarski N, Krasemann S, Lichtenthaler SF, Müller SA, Colombo A, Monasor LS, ... ... Herms J, et al. Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. Nature Neuroscience. PMID 30617257 DOI: 10.1038/S41593-018-0296-9  0.589
2019 Brendel M, Barthel H, Eimeren Tv, Marek K, Beyer L, Song M, Palleis C, Respondek G, Sauerbeck J, Hammes J, Barbe M, Onur OA, Jessen F, Saur D, Schroeter ML, ... ... Herms J, et al. Ic-P-161: 18F-Pi2620 Tau-Pet In Progressive Supranuclear Palsy: A Multi-Center Evaluation Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2783  0.573
2018 Brendel M, Jaworska A, Overhoff F, Blume T, Probst F, Gildehaus FJ, Bartenstein P, Haass C, Bohrmann B, Herms J, Willem M, Rominger A. Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation. Theranostics. 8: 4957-4968. PMID 30429879 DOI: 10.7150/Thno.27868  0.638
2018 Blume T, Focke C, Peters F, Deussing M, Albert NL, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Ozmen L, Baumann K, Bartenstein P, Rominger A, Herms J, Brendel M. Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study. Journal of Neuroinflammation. 15: 307. PMID 30400912 DOI: 10.1186/S12974-018-1347-6  0.614
2018 Focke C, Blume T, Zott B, Yuan Shi Y, Deussing M, Peters F, Schmidt C, Kleinberger G, Lindner S, Gildehaus FJ, Beyer L, von Ungern-Sternberg B, Bartenstein P, Ozmen L, Baumann K, ... ... Herms J, et al. Early and longitudinal microglial activation but not amyloid accumulation predict cognitive outcome in PS2APP mice. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30262517 DOI: 10.2967/Jnumed.118.217703  0.595
2018 Unterrainer M, Fleischmann DF, Diekmann C, Vomacka L, Lindner S, Vettermann F, Brendel M, Wenter V, Ertl-Wagner B, Herms J, Wetzel C, Rupprecht R, Tonn JC, Belka C, Bartenstein P, et al. Comparison of F-GE-180 and dynamic F-FET PET in high grade glioma: a double-tracer pilot study. European Journal of Nuclear Medicine and Molecular Imaging. PMID 30244386 DOI: 10.1007/S00259-018-4166-1  0.587
2018 Xiang X, Piers TM, Wefers B, Zhu K, Mallach A, Brunner B, Kleinberger G, Song W, Colonna M, Herms J, Wurst W, Pocock JM, Haass C. The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans. Molecular Neurodegeneration. 13: 49. PMID 30185230 DOI: 10.1186/S13024-018-0280-6  0.343
2018 Blume T, Filser S, Jaworska A, Blain JF, Koenig G, Moschke K, Lichtenthaler SF, Herms J. BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines. Frontiers in Aging Neuroscience. 10: 229. PMID 30093858 DOI: 10.3389/Fnagi.2018.00229  0.374
2018 Rammes G, Seeser F, Mattusch K, Zhu K, Haas L, Kummer M, Heneka M, Herms J, Parsons CG. The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (Aβ) species on long-term potentiation (LTP). Neuropharmacology. PMID 30016667 DOI: 10.1016/J.Neuropharm.2018.07.021  0.35
2018 Zhu K, Peters F, Filser S, Herms J. Consequences of Pharmacological BACE Inhibition on Synaptic Structure and Function. Biological Psychiatry. PMID 29945719 DOI: 10.1016/J.Biopsych.2018.04.022  0.386
2018 Crux S, Herms J, Dorostkar MM. Tcf4 regulates dendritic spine density and morphology in the adult brain. Plos One. 13: e0199359. PMID 29933371 DOI: 10.1371/Journal.Pone.0199359  0.317
2018 Brendel M, Yousefi BH, Blume T, Herz M, Focke C, Deussing M, Peters F, Lindner S, von Ungern-Sternberg B, Drzezga A, Bartenstein P, Haass C, Okamura N, Herms J, Yakushev I, et al. Comparison of F-T807 and F-THK5117 PET in a Mouse Model of Tau Pathology. Frontiers in Aging Neuroscience. 10: 174. PMID 29930508 DOI: 10.3389/Fnagi.2018.00174  0.629
2018 Deussing M, Blume T, Vomacka L, Mahler C, Focke C, Todica A, Unterrainer M, Albert NL, Lindner S, von Ungern-Sternberg B, Baumann K, Zwergal A, Bartenstein P, Herms J, Rominger A, et al. Data on specificity of [F]GE180 uptake for TSPO expression in rodent brain and myocardium. Data in Brief. 19: 331-336. PMID 29892655 DOI: 10.1016/J.Dib.2018.04.133  0.575
2018 Unterrrainer M, Winkelmann I, Suchorska B, Giese A, Wenter V, Kreth FW, Herms J, Bartenstein P, Tonn JC, Albert NL. Biological tumour volumes of gliomas in early and standard 20-40 minF-FET PET images differ according to IDH mutation status. European Journal of Nuclear Medicine and Molecular Imaging. PMID 29487977 DOI: 10.1007/S00259-018-3969-4  0.353
2018 Peters F, Salihoglu H, Rodrigues E, Herzog E, Blume T, Filser S, Dorostkar M, Shimshek DR, Brose N, Neumann U, Herms J. BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology. Acta Neuropathologica. PMID 29327084 DOI: 10.1007/S00401-017-1804-9  0.583
2017 Deussing M, Blume T, Vomacka L, Mahler C, Focke C, Todica A, Unterrainer M, Albert NL, Lindner S, von Ungern-Sternberg B, Baumann K, Zwergal A, Bartenstein P, Herms J, Rominger A, et al. Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [(18)F]GE180 PET quantification. Neuroimage. PMID 28988133 DOI: 10.1016/J.Neuroimage.2017.10.006  0.586
2017 Brendel M, Focke C, Blume T, Peters F, Deussing M, Probst F, Jaworska A, Overhoff F, Albert N, Lindner S, von Ungern-Sternberg B, Bartenstein P, Haass C, Kleinberger G, Herms J, et al. Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life-Span of Wild-Type Mice: A PET Study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28705919 DOI: 10.2967/Jnumed.117.195107  0.608
2017 Montagna E, Dorostkar MM, Herms J. The Role of APP in Structural Spine Plasticity. Frontiers in Molecular Neuroscience. 10: 136. PMID 28539872 DOI: 10.3389/Fnmol.2017.00136  0.315
2017 Blumenstock S, Rodrigues EF, Peters F, Blazquez-Llorca L, Schmidt F, Giese A, Herms J. Seeding and transgenic overexpression of alpha-synuclein triggers dendritic spine pathology in the neocortex. Embo Molecular Medicine. PMID 28351932 DOI: 10.15252/Emmm.201607305  0.328
2017 Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, ... Herms J, et al. Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis. Frontiers in Aging Neuroscience. 9: 8. PMID 28197095 DOI: 10.3389/Fnagi.2017.00008  0.63
2017 Rammes G, Mattusch C, Wulff M, Seeser F, Kreuzer M, Zhu K, Deussing JM, Herms J, Parsons CG. Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aβ) in murine models of Alzheimer's disease (AD). Neuropharmacology. PMID 28174113 DOI: 10.1016/J.Neuropharm.2017.02.003  0.401
2017 Blazquez-Llorca L, Valero-Freitag S, Rodrigues EF, Merchán-Pérez Á, Rodríguez JR, Dorostkar MM, DeFelipe J, Herms J. High plasticity of axonal pathology in Alzheimer's disease mouse models. Acta Neuropathologica Communications. 5: 14. PMID 28173876 DOI: 10.1186/S40478-017-0415-Y  0.312
2017 Schön C, Herms J. In Vivo Imaging of Tau Aggregates in the Mouse Retina. Methods in Molecular Biology (Clifton, N.J.). 1523: 361-368. PMID 27975264 DOI: 10.1007/978-1-4939-6598-4_24  0.361
2017 Xu AJ, Marinkovic P, Herms J. Imaging Of Ageing And Seeding Effects On Tau Pathology In The Mouse Tauopathy Model Alzheimers & Dementia. 13: 1293. DOI: 10.1016/J.Jalz.2017.06.1957  0.309
2016 Zhu K, Xiang X, Filser S, Marinković P, Dorostkar MM, Crux S, Neumann U, Shimshek DR, Rammes G, Haass C, Lichtenthaler SF, Gunnersen JM, Herms J. Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6. Biological Psychiatry. PMID 28129943 DOI: 10.1016/J.Biopsych.2016.12.023  0.353
2016 Ovsepian SV, Blazquez-Llorca L, Freitag SV, Rodrigues EF, Herms J. Ambient Glutamate Promotes Paroxysmal Hyperactivity in Cortical Pyramidal Neurons at Amyloid Plaques via Presynaptic mGluR1 Receptors. Cerebral Cortex (New York, N.Y. : 1991). PMID 27600841 DOI: 10.1093/Cercor/Bhw267  0.354
2016 Zou C, Crux S, Marinesco S, Montagna E, Sgobio C, Shi Y, Shi S, Zhu K, Dorostkar MM, Müller UC, Herms J. Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D-serine homeostasis. The Embo Journal. PMID 27572463 DOI: 10.15252/Embj.201694085  0.343
2016 Overhoff F, Brendel M, Jaworska A, Korzhova V, Delker A, Probst F, Focke C, Gildehaus FJ, Carlsen J, Baumann K, Haass C, Bartenstein P, Herms J, Rominger A. Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice. Frontiers in Neuroscience. 10: 45. PMID 26973442 DOI: 10.3389/Fnins.2016.00045  0.618
2016 Brendel M, Jaworska A, Probst F, Overhoff F, Korzhova V, Lindner S, Carlsen J, Bartenstein P, Harada R, Kudo Y, Haass C, van Leuven F, Okamura N, Herms J, Rominger A. microPET Imaging of Tau Pathology with [18F]-THK5117 in two Transgenic Mouse Models. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26912432 DOI: 10.2967/Jnumed.115.163493  0.7
2016 Brendel M, Probst F, Jaworska A, Overhoff F, Korzhova V, Albert N, Beck R, Lindner S, Gildehaus FJ, Baumann K, Bartenstein P, Kleinberger G, Haass C, Herms J, Rominger A. Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple Tracer PET Study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26912428 DOI: 10.2967/Jnumed.115.167858  0.619
2016 Herms J, Dorostkar MM. Dendritic Spine Pathology in Neurodegenerative Diseases. Annual Review of Pathology. PMID 26907528 DOI: 10.1146/Annurev-Pathol-012615-044216  0.338
2016 Zou C, Shi Y, Ohli J, Schüller U, Dorostkar MM, Herms J. Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer's disease. Acta Neuropathologica. PMID 26724934 DOI: 10.1007/S00401-015-1527-8  0.398
2015 Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A. Monitoring of chronic γ-secretase modulator treatment by serial amyloid-PET. Molecular Psychiatry. 20: 1141. PMID 26401838 DOI: 10.1038/mp.2015.146  0.533
2015 Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, ... ... Herms J, et al. η-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. PMID 26322584 DOI: 10.1038/Nature14864  0.357
2015 Dorostkar MM, Zou C, Blazquez-Llorca L, Herms J. Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities. Acta Neuropathologica. 130: 1-19. PMID 26063233 DOI: 10.1007/S00401-015-1449-5  0.369
2015 Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A. Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment. Molecular Psychiatry. 20: 1179-87. PMID 26055427 DOI: 10.1038/mp.2015.74  0.353
2015 Zou C, Montagna E, Shi Y, Peters F, Blazquez-Llorca L, Shi S, Filser S, Dorostkar MM, Herms J. Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer's disease. Acta Neuropathologica. 129: 909-20. PMID 25862638 DOI: 10.1007/S00401-015-1421-4  0.428
2015 Jung CK, Keppler K, Steinbach S, Blazquez-Llorca L, Herms J. Fibrillar amyloid plaque formation precedes microglial activation. Plos One. 10: e0119768. PMID 25799372 DOI: 10.1371/Journal.Pone.0119768  0.405
2015 Blazquez-Llorca L, Hummel E, Zimmerman H, Zou C, Burgold S, Rietdorf J, Herms J. Correlation of two-photon in vivo imaging and FIB/SEM microscopy. Journal of Microscopy. 259: 129-36. PMID 25786682 DOI: 10.1111/Jmi.12231  0.312
2015 Brendel M, Jaworska A, Grießinger E, Rötzer C, Burgold S, Gildehaus FJ, Carlsen J, Cumming P, Baumann K, Haass C, Steiner H, Bartenstein P, Herms J, Rominger A. Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models. Plos One. 10: e0116678. PMID 25706990 DOI: 10.1371/Journal.Pone.0116678  0.617
2015 Filser S, Ovsepian SV, Masana M, Blazquez-Llorca L, Brandt Elvang A, Volbracht C, Müller MB, Jung CK, Herms J. Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions. Biological Psychiatry. 77: 729-39. PMID 25599931 DOI: 10.1016/J.Biopsych.2014.10.013  0.352
2015 Thon N, Kunz M, Lemke L, Jansen NL, Eigenbrod S, Kreth S, Lutz J, Egensperger R, Giese A, Herms J, Weller M, Kretzschmar H, Tonn JC, La Fougère C, Kreth FW. Dynamic 18F-FET PET in suspected WHO grade II gliomas defines distinct biological subgroups with different clinical courses International Journal of Cancer. 136: 2132-2145. PMID 25311315 DOI: 10.1002/Ijc.29259  0.358
2015 Ochs SM, Dorostkar MM, Aramuni G, Schön C, Filser S, Pöschl J, Kremer A, Van Leuven F, Ovsepian SV, Herms J. Loss of neuronal GSK3β reduces dendritic spine stability and attenuates excitatory synaptic transmission via β-catenin. Molecular Psychiatry. 20: 482-9. PMID 24912492 DOI: 10.1038/Mp.2014.55  0.527
2015 Brendel M, Jaworska A, Herms J, Trambauer J, Rötzer C, Gildehaus FJ, Carlsen J, Cumming P, Bylund J, Luebbers T, Bartenstein P, Steiner H, Haass C, Baumann K, Rominger A. Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment Molecular Psychiatry. DOI: 10.1038/mp.2015.74  0.531
2014 Honarnejad K, Daschner A, Gehring AP, Szybinska A, Giese A, Kuznicki J, Bracher F, Herms J. Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease. Translational Psychiatry. 4: e489. PMID 25514752 DOI: 10.1038/Tp.2014.132  0.362
2014 Dorostkar MM, Burgold S, Filser S, Barghorn S, Schmidt B, Anumala URa, Hillen H, Klein C, Herms J. Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer's disease mouse model Brain : a Journal of Neurology. 137: 3319-3326. PMID 25281869 DOI: 10.1093/Brain/Awu280  0.402
2014 Kleele T, Marinkovi? P, Williams PR, Stern S, Weigand EE, Engerer P, Naumann R, Hartmann J, Karl RM, Bradke F, Bishop D, Herms J, Konnerth A, Kerschensteiner M, Godinho L, et al. An assay to image neuronal microtubule dynamics in mice. Nature Communications. 5: 4827. PMID 25219969 DOI: 10.1038/Ncomms5827  0.303
2014 Neuner J, Ovsepian SV, Dorostkar M, Filser S, Gupta A, Michalakis S, Biel M, Herms J. Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb. Nature Communications. 5: 3915. PMID 24867427 DOI: 10.1038/Ncomms4915  0.306
2014 Burgold S, Filser S, Dorostkar MM, Schmidt B, Herms J. In vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques Acta Neuropathologica Communications. 2: 30. PMID 24678659 DOI: 10.1186/2051-5960-2-30  0.38
2014 Brendel M, Delker A, Rötzer C, Böning G, Carlsen J, Cyran C, Mille E, Gildehaus FJ, Cumming P, Baumann K, Steiner H, Haass C, Herms J, Bartenstein P, Rominger A. Impact of partial volume effect correction on cerebral β-amyloid imaging in APP-Swe mice using [(18)F]-florbetaben PET. Neuroimage. 84: 843-53. PMID 24055703 DOI: 10.1016/J.Neuroimage.2013.09.017  0.651
2014 Ovsepian SV, Antyborzec I, O'Leary VB, Zaborszky L, Herms J, Oliver Dolly J. Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons. Brain Structure & Function. 219: 1527-41. PMID 23716278 DOI: 10.1007/S00429-013-0583-X  0.336
2014 Rominger A, Brendel M, Rötzer C, Gildehaus F, Baumann K, Haass C, Steiner H, Herms J, Bartenstein P. Monitoring Of Long-Term Gamma Secretase Modulation Treatment In App-Swe Mice By Means Of [18F]-Florbetaben Pet Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.04.113  0.592
2013 Ovsepian SV, Herms J. Cholinergic neurons-keeping check on amyloid β in the cerebral cortex. Frontiers in Cellular Neuroscience. 7: 252. PMID 24376398 DOI: 10.3389/Fncel.2013.00252  0.338
2013 Hoffmann NA, Dorostkar MM, Blumenstock S, Goedert M, Herms J. Impaired plasticity of cortical dendritic spines in P301S tau transgenic mice. Acta Neuropathologica Communications. 1: 82. PMID 24344647 DOI: 10.1186/2051-5960-1-82  0.394
2013 Honarnejad K, Daschner A, Giese A, Zall A, Schmidt B, Szybinska A, Kuznicki J, Herms J. Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease Plos One. 8. PMID 24260442 DOI: 10.1371/Journal.Pone.0080645  0.306
2013 Honarnejad K, Kirsch AK, Daschner A, Szybinska A, Kuznicki J, Herms J. FRET-based calcium imaging: A tool for high-throughput/content phenotypic drug screening in alzheimer disease Journal of Biomolecular Screening. 18: 1309-1320. PMID 24221842 DOI: 10.1177/1087057113502672  0.31
2013 Anumala UR, Gu J, Lo Monte F, Kramer T, Heyny-von Haußen R, Hölzer J, Goetschy-Meyer V, Schön C, Mall G, Hilger I, Czech C, Herms J, Schmidt B. Fluorescent rhodanine-3-acetic acids visualize neurofibrillary tangles in Alzheimer's disease brains. Bioorganic & Medicinal Chemistry. 21: 5139-44. PMID 23859773 DOI: 10.1016/J.Bmc.2013.06.039  0.335
2013 Ovsepian SV, Herms J. Drain of the brain: Low-affinity p75 neurotrophin receptor affords a molecular sink for clearance of cortical amyloid β by the cholinergic modulator system Neurobiology of Aging. 34: 2517-2524. PMID 23747048 DOI: 10.1016/J.Neurobiolaging.2013.05.005  0.343
2013 Rominger A, Brendel M, Burgold S, Keppler K, Baumann K, Xiong G, Mille E, Gildehaus FJ, Carlsen J, Schlichtiger J, Niedermoser S, Wängler B, Cumming P, Steiner H, Herms J, et al. Longitudinal assessment of cerebral β-amyloid deposition in mice overexpressing Swedish mutant β-amyloid precursor protein using 18F-florbetaben PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1127-34. PMID 23729696 DOI: 10.2967/Jnumed.112.114660  0.655
2013 Honarnejad K, Jung CKE, Lammich S, Arzberger T, Kretzschmar H, Herms J. Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease Journal of Cellular and Molecular Medicine. 17: 293-302. PMID 23379308 DOI: 10.1111/Jcmm.12008  0.313
2013 Brendel M, Böning G, Delker A, Rötzer C, Gildehaus F, Baumann K, Steiner H, Haass C, Herms J, Bartenstein P, Rominger A. PET imaging using [18F]florbetaben in Alzheimer's disease mouse models Alzheimers & Dementia. 9: 29. DOI: 10.1016/J.Jalz.2013.05.041  0.614
2012 Schön C, Hoffmann NA, Ochs SM, Burgold S, Filser S, Steinbach S, Seeliger MW, Arzberger T, Goedert M, Kretzschmar HA, Schmidt B, Herms J. Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice. Plos One. 7: e53547. PMID 23300938 DOI: 10.1371/Journal.Pone.0053547  0.392
2012 Dorostkar MM, Herms J. Arc illuminates Alzheimer's pathophysiology Nature Neuroscience. 15: 1323-1325. PMID 23007183 DOI: 10.1038/Nn.3226  0.343
2012 Bittner T, Burgold S, Dorostkar MM, Fuhrmann M, Wegenast-Braun BM, Schmidt B, Kretzschmar H, Herms J. Amyloid plaque formation precedes dendritic spine loss Acta Neuropathologica. 124: 797-807. PMID 22993126 DOI: 10.1007/S00401-012-1047-8  0.369
2012 Boländer A, Kieser D, Voss C, Bauer S, Schön C, Burgold S, Bittner T, Hölzer J, Heyny-Von Haußen R, Mall G, Goetschy V, Czech C, Knust H, Berger R, Herms J, et al. Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines As imaging agents for tau fibrils and β-Amyloid plaques in alzheimers disease models Journal of Medicinal Chemistry. 55: 9170-9180. PMID 22913544 DOI: 10.1021/Jm300653B  0.397
2012 Honarnejad K, Herms J. Presenilins: Role in calcium homeostasis International Journal of Biochemistry and Cell Biology. 44: 1983-1986. PMID 22842534 DOI: 10.1016/J.Biocel.2012.07.019  0.303
2012 Frick A, Grammel D, Schmidt F, Pöschl J, Priller M, Pagella P, von Bueren AO, Peraud A, Tonn JC, Herms J, Rutkowski S, Kretzschmar HA, Schüller U. Proper cerebellar development requires expression of β1-integrin in Bergmann glia, but not in granule neurons. Glia. 60: 820-32. PMID 22374686 DOI: 10.1002/Glia.22314  0.305
2012 Jung CKE, Herms J. Role of APP for dendritic spine formation and stability Experimental Brain Research. 217: 463-470. PMID 22094714 DOI: 10.1007/S00221-011-2939-X  0.371
2012 Hokkanen S, Feldmann HM, Ding H, Jung CKE, Bojarski L, ller IRM, Schüller U, Kretzschmar H, Wolf E, Herms J. Lack of pur-alpha alters postnatal brain development and causes megalencephaly Human Molecular Genetics. 21: 473-484. PMID 22010047 DOI: 10.1093/Hmg/Ddr476  0.343
2012 Rominger A, Brendel M, Baumann K, Gildehaus F, Niedermoser S, Wängler B, Burgold S, Herms J, Cumming P, Steiner H, Haass C, Bartenstein P. Longitudinal imaging of cerebral beta-amyloid in APP-swe mice using [18F]florbetaben PET Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.411  0.612
2012 Rominger A, Brendel M, Baumann K, Gildehaus F, Niedermoser S, Wängler B, Burgold S, Herms J, Cumming P, Steiner H, Haass C, Bartenstein P. Longitudinal imaging of cerebral Aβ in APP-Swe mice using [18F]florbetaben PET Alzheimers & Dementia. 8: 11. DOI: 10.1016/J.Jalz.2012.05.033  0.628
2011 Jung CK, Fuhrmann M, Honarnejad K, Van Leuven F, Herms J. Role of presenilin 1 in structural plasticity of cortical dendritic spines in vivo. Journal of Neurochemistry. 119: 1064-73. PMID 21951279 DOI: 10.1111/J.1471-4159.2011.07503.X  0.562
2011 Pöschl J, Lorenz A, Hartmann W, von Bueren AO, Kool M, Li S, Peraud A, Tonn JC, Herms J, Xiang M, Rutkowski S, Kretzschmar HA, Schüller U. Expression of BARHL1 in medulloblastoma is associated with prolonged survival in mice and humans. Oncogene. 30: 4721-30. PMID 21602885 DOI: 10.1038/Onc.2011.173  0.335
2011 Hüls S, Högen T, Vassallo N, Danzer KM, Hengerer B, Giese A, Herms J. AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers Journal of Neurochemistry. 117: 868-878. PMID 21426349 DOI: 10.1111/J.1471-4159.2011.07254.X  0.301
2011 Kunz M, Thon N, Eigenbrod S, Hartmann C, Egensperger R, Herms J, Geisler J, la Fougere C, Lutz J, Linn J, Kreth S, von Deimling A, Tonn JC, Kretzschmar HA, Pöpperl G, et al. Hot spots in dynamic (18)FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas. Neuro-Oncology. 13: 307-16. PMID 21292686 DOI: 10.1093/Neuonc/Noq196  0.308
2011 Burgold S, Bittner T, Dorostkar MM, Kieser D, Fuhrmann M, Mitteregger G, Kretzschmar H, Schmidt B, Herms J. In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks Acta Neuropathologica. 121: 327-335. PMID 21136067 DOI: 10.1007/S00401-010-0787-6  0.395
2011 Schmidt B, Kieser D, Boländer A, Haussen RH, Burgold S, Herms J. Fluorescent dyes detect Aβ- and Tau-pathology post mortem and in vivo Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.888  0.302
2011 Herms J, Bittner T, Fuhrmann M, Burgold S, Nadine H, Jung C. Tau dependent spine loss in Alzheimer's disease mice Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1990  0.372
2011 Fuhrmann M, Ochs S, Keppler K, Langer A, Hoelter S, Herms J. Role of chemokine receptor CX3CR1 in Alzheimer's transgenic mice Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1590  0.332
2010 Bittner T, Fuhrmann M, Burgold S, Ochs SM, Hoffmann N, Mitteregger G, Kretzschmar H, LaFerla FM, Herms J. Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice. Plos One. 5: e15477. PMID 21103384 DOI: 10.1371/Journal.Pone.0015477  0.412
2010 Fuhrmann M, Bittner T, Jung CK, Burgold S, Page RM, Mitteregger G, Haass C, LaFerla FM, Kretzschmar H, Herms J. Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease. Nature Neuroscience. 13: 411-3. PMID 20305648 DOI: 10.1038/Nn.2511  0.35
2009 Bittner T, Fuhrmann M, Burgold S, Jung CK, Volbracht C, Steiner H, Mitteregger G, Kretzschmar HA, Haass C, Herms J. Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10405-9. PMID 19692615 DOI: 10.1523/Jneurosci.2288-09.2009  0.391
2009 Mitteregger G, Korte S, Shakarami M, Herms J, Kretzschmar HA. Role of copper and manganese in prion disease progression. Brain Research. 1292: 155-64. PMID 19635464 DOI: 10.1016/J.Brainres.2009.07.051  0.309
2009 Priller C, Mitteregger G, Paluch S, Vassallo N, Staufenbiel M, Kretzschmar HA, Jucker M, Herms J. Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice. Neurobiology of Aging. 30: 1227-37. PMID 18077058 DOI: 10.1016/J.Neurobiolaging.2007.10.016  0.336
2009 Dewachter I, Filipkowski RK, Priller C, Ris L, Neyton J, Croes S, Terwel D, Gysemans M, Devijver H, Borghgraef P, Godaux E, Kaczmarek L, Herms J, Van Leuven F. Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice. Neurobiology of Aging. 30: 241-56. PMID 17673336 DOI: 10.1016/J.Neurobiolaging.2007.06.011  0.519
2009 Fuhrmann M, Bittner T, Jung C, Burgold S, Mitteregger G, Kretzschmar H, LaFerla FM, Herms J. Microglia mediated and fractalkine receptor dependent neuron loss in a mouse model of Alzheimer's disease Alzheimers & Dementia. 5: 82. DOI: 10.1016/J.Jalz.2009.05.207  0.327
2009 Burgold S, Fuhrmann M, Schmidt B, Kretzschmar H, Herms J. Kinetics of dendritic structural plasticity in the living brain of an Alzheimer's disease mouse model acquired with two photon microscopy Alzheimers & Dementia. 5: 439. DOI: 10.1016/J.Jalz.2009.04.897  0.347
2009 Bittner T, Fuhrmann M, Burgold S, Kretzschmar H, LaFerla FM, Herms J. Long-term in vivo imaging identifies multiple events that trigger dendritic spine loss in 3xTg-AD mice Alzheimers & Dementia. 5: 438. DOI: 10.1016/J.Jalz.2009.04.894  0.345
2009 Jung CKE, Honarnejad K, Leuven FV, Herms J. In vivo analysis of the effect of mutant PS1 on dendritic spines in the somatosensory cortex of transgenic mice Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.04.506  0.307
2009 Hoffmann NA, Bittner T, Burgold S, LaFerla FM, Kretzschmar HA, Herms J. P3-181: Ultrastructural investigation of tau-dependent dendropathy in a triple transgenic mouse model of Alzheimer's disease Alzheimer's & Dementia. 5: P396-P397. DOI: 10.1016/J.Jalz.2009.04.1055  0.367
2008 Mehrkens JH, Pp̈pperl G, Rachinger W, Herms J, Seelos K, Tatsch K, Tonn JC, Kreth FW. The positive predictive value of O-(2-[18F]fluoroethyl)-l- tyrosine (FET) PET in the diagnosis of a glioma recurrence after multimodal treatment Journal of Neuro-Oncology. 88: 27-35. PMID 18217207 DOI: 10.1007/S11060-008-9526-4  0.351
2008 Bojarski L, Herms J, Kuznicki J. Calcium dysregulation in Alzheimer's disease Neurochemistry International. 52: 621-633. PMID 18035450 DOI: 10.1016/J.Neuint.2007.10.002  0.344
2008 Linn J, Herms J, Dichgans M, Brückmann H, Fesl G, Freilinger T, Wiesmann M. Subarachnoid hemosiderosis and superficial cortical hemosiderosis in cerebral amyloid angiopathy. Ajnr. American Journal of Neuroradiology. 29: 184-6. PMID 17947366 DOI: 10.3174/Ajnr.A0783  0.319
2007 Pöpperl G, Kreth FW, Mehrkens JH, Herms J, Seelos K, Koch W, Gildehaus FJ, Kretzschmar HA, Tonn JC, Tatsch K. FET PET for the evaluation of untreated gliomas: correlation of FET uptake and uptake kinetics with tumour grading. European Journal of Nuclear Medicine and Molecular Imaging. 34: 1933-42. PMID 17763848 DOI: 10.1007/S00259-007-0534-Y  0.324
2007 Ring S, Weyer SW, Kilian SB, Waldron E, Pietrzik CU, Filippov MA, Herms J, Buchholz C, Eckman CB, Korte M, Wolfer DP, Müller UC. The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7817-26. PMID 17634375 DOI: 10.1523/Jneurosci.1026-07.2007  0.388
2007 Fuhrmann M, Mitteregger G, Kretzschmar H, Herms J. Dendritic pathology in prion disease starts at the synaptic spine Journal of Neuroscience. 27: 6224-6233. PMID 17553995 DOI: 10.1523/Jneurosci.5062-06.2007  0.319
2007 Priller C, Dewachter I, Vassallo N, Paluch S, Pace C, Kretzschmar HA, Van Leuven F, Herms J. Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons. The Journal of Biological Chemistry. 282: 1119-27. PMID 17088253 DOI: 10.1074/Jbc.M605066200  0.528
2006 Priller C, Bauer T, Mitteregger G, Krebs B, Kretzschmar HA, Herms J. Synapse formation and function is modulated by the amyloid precursor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7212-21. PMID 16822978 DOI: 10.1523/Jneurosci.1450-06.2006  0.325
2005 Rachinger W, Goetz C, Pöpperl G, Gildehaus FJ, Kreth FW, Holtmannspötter M, Herms J, Koch W, Tatsch K, Tonn JC. Positron emission tomography with O-(2-[18F]flouroethyl)-L- tyrosine versus magnetic resonance imaging in the diagnosis of recurrent gliomas Neurosurgery. 57: 505-511. PMID 16145529 DOI: 10.1227/01.Neu.0000171642.49553.B0  0.33
2004 Herms J, Anliker B, Heber S, Ring S, Fuhrmann M, Kretzschmar H, Sisodia S, Müller U. Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members Embo Journal. 23: 4106-4115. PMID 15385965 DOI: 10.1038/Sj.Emboj.7600390  0.35
2003 Herms J, Schneider I, Dewachter I, Caluwaerts N, Kretzschmar H, Van Leuven F. Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein. The Journal of Biological Chemistry. 278: 2484-9. PMID 12431992 DOI: 10.1074/Jbc.M206769200  0.524
2001 Schneider I, Reverse D, Dewachter I, Ris L, Caluwaerts N, Kuiperi C, Gilis M, Geerts H, Kretzschmar H, Godaux E, Moechars D, Van Leuven F, Herms J. Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation. The Journal of Biological Chemistry. 276: 11539-44. PMID 11278803 DOI: 10.1074/Jbc.M010977200  0.561
2001 Augustin I, Korte S, Rickmann M, Kretzschmar HA, Südhof TC, Herms JW, Brose N. The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 10-7. PMID 11150314 DOI: 10.1523/Jneurosci.21-01-00010.2001  0.472
2000 Heber S, Herms J, Gajic V, Hainfellner J, Aguzzi A, Rulicke T, Kretzschmar H, Von Koch C, Sisodia S, Tremml P, Lipp HP, Wolfer DP, Muller U. Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members Journal of Neuroscience. 20: 7951-7963. PMID 11050115 DOI: 10.1523/Jneurosci.20-21-07951.2000  0.364
1999 Herms J, Tings T, Gall S, Madlung A, Giese A, Siebert H, Schürmann P, Windl O, Brose N, Kretzschmar H. Evidence of presynaptic location and function of the prion protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8866-75. PMID 10516306 DOI: 10.1523/Jneurosci.19-20-08866.1999  0.529
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