| Year |
Citation |
Score |
| 2024 |
Dasmeh P, Zheng J, Erdoğan AN, Tokuriki N, Wagner A. Rapid evolutionary change in trait correlations of single proteins. Nature Communications. 15: 3327. PMID 38637501 DOI: 10.1038/s41467-024-46658-1 |
0.727 |
|
| 2024 |
Schmutzer M, Dasmeh P, Wagner A. Frustration can Limit the Adaptation of Promiscuous Enzymes Through Gene Duplication and Specialisation. Journal of Molecular Evolution. 92: 104-120. PMID 38470504 DOI: 10.1007/s00239-024-10161-4 |
0.671 |
|
| 2022 |
Karve S, Dasmeh P, Zheng J, Wagner A. Low protein expression enhances phenotypic evolvability by intensifying selection on folding stability. Nature Ecology & Evolution. PMID 35798838 DOI: 10.1038/s41559-022-01797-w |
0.708 |
|
| 2022 |
Iyengar BR, Wagner A. GroEL/S overexpression helps to purge deleterious mutations and reduce genetic diversity during adaptive protein evolution. Molecular Biology and Evolution. PMID 35234895 DOI: 10.1093/molbev/msac047 |
0.309 |
|
| 2021 |
Dasmeh P, Doronin R, Wagner A. The length scale of multivalent interactions is evolutionarily conserved in fungal and vertebrate phase-separating proteins. Genetics. PMID 34791214 DOI: 10.1093/genetics/iyab184 |
0.702 |
|
| 2021 |
Dasmeh P, Wagner A. Yeast Proteins may Reversibly Aggregate like Amphiphilic Molecules. Journal of Molecular Biology. 434: 167352. PMID 34774567 DOI: 10.1016/j.jmb.2021.167352 |
0.692 |
|
| 2020 |
Dasmeh P, Wagner A. Natural selection on the phase-separation properties of FUS during 160 million years of mammalian evolution. Molecular Biology and Evolution. PMID 33022038 DOI: 10.1093/molbev/msaa258 |
0.688 |
|
| 2020 |
Schweizer G, Wagner A. Genotype networks of 80 quantitative Arabidopsis thaliana phenotypes reveal phenotypic evolvability despite pervasive epistasis. Plos Computational Biology. 16: e1008082. PMID 32790763 DOI: 10.1371/Journal.Pcbi.1008082 |
0.393 |
|
| 2020 |
Moerman F, Fronhofer EA, Wagner A, Altermatt F. Gene swamping alters evolution during range expansions in the protist . Biology Letters. 16: 20200244. PMID 32544380 DOI: 10.1098/Rsbl.2020.0244 |
0.356 |
|
| 2019 |
Zheng J, Payne JL, Wagner A. Cryptic genetic variation accelerates evolution by opening access to diverse adaptive peaks. Science (New York, N.Y.). 365: 347-353. PMID 31346060 DOI: 10.1126/Science.Aax1837 |
0.378 |
|
| 2019 |
Aguilar-Rodríguez J, Fares MA, Wagner A. Chaperonin overproduction and metabolic erosion caused by mutation accumulation in Escherichia coli. Fems Microbiology Letters. 366. PMID 31150542 DOI: 10.1093/Femsle/Fnz121 |
0.78 |
|
| 2018 |
Payne JL, Wagner A. The causes of evolvability and their evolution. Nature Reviews. Genetics. PMID 30385867 DOI: 10.1038/S41576-018-0069-Z |
0.353 |
|
| 2018 |
Aguilar-Rodríguez J, Wagner A. Metabolic determinants of enzyme evolution in a genome-scale bacterial metabolic network. Genome Biology and Evolution. PMID 30351420 DOI: 10.1093/Gbe/Evy234 |
0.775 |
|
| 2018 |
Schaerli Y, Jiménez A, Duarte JM, Mihajlovic L, Renggli J, Isalan M, Sharpe J, Wagner A. Synthetic circuits reveal how mechanisms of gene regulatory networks constrain evolution. Molecular Systems Biology. 14: e8102. PMID 30201776 DOI: 10.15252/Msb.20178102 |
0.42 |
|
| 2018 |
Hosseini SR, Wagner A. Genomic organization underlying deletional robustness in bacterial metabolic systems. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915048 DOI: 10.1073/Pnas.1717243115 |
0.366 |
|
| 2018 |
Sprouffske K, Aguílar-Rodríguez J, Sniegowski P, Wagner A. High mutation rates limit evolutionary adaptation in Escherichia coli. Plos Genetics. 14: e1007324. PMID 29702649 DOI: 10.1371/Journal.Pgen.1007324 |
0.78 |
|
| 2018 |
Aguilar-Rodríguez J, Peel L, Stella M, Wagner A, Payne JL. The architecture of an empirical genotype-phenotype map. Evolution; International Journal of Organic Evolution. PMID 29676774 DOI: 10.1111/Evo.13487 |
0.762 |
|
| 2018 |
Chu HY, Sprouffske K, Wagner A. Assessing the benefits of horizontal gene transfer by laboratory evolution and genome sequencing. Bmc Evolutionary Biology. 18: 54. PMID 29673327 DOI: 10.1186/S12862-018-1164-7 |
0.353 |
|
| 2018 |
Payne JL, Khalid F, Wagner A. RNA-mediated gene regulation is less evolvable than transcriptional regulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581298 DOI: 10.1073/Pnas.1719138115 |
0.302 |
|
| 2018 |
Catalán P, Wagner A, Manrubia S, Cuesta JA. Adding levels of complexity enhances robustness and evolvability in a multilevel genotype-phenotype map. Journal of the Royal Society, Interface. 15. PMID 29321269 DOI: 10.1098/Rsif.2017.0516 |
0.369 |
|
| 2018 |
Vahdati AR, Wagner A. Population size affects adaptation in complex ways: simulations on empirical adaptive landscapes Evolutionary Biology-New York. 45: 156-169. DOI: 10.1007/S11692-017-9440-9 |
0.331 |
|
| 2017 |
Vahdati AR, Sprouffske K, Wagner A. Effect of Population Size and Mutation Rate on the Evolution of RNA Sequences on an Adaptive Landscape Determined by RNA Folding. International Journal of Biological Sciences. 13: 1138-1151. PMID 29104505 DOI: 10.7150/Ijbs.19436 |
0.341 |
|
| 2017 |
Fortuna MA, Zaman L, Wagner A, Bascompte J. Non-adaptive origins of evolutionary innovations increase network complexity in interacting digital organisms. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 29061902 DOI: 10.1098/Rstb.2016.0431 |
0.349 |
|
| 2017 |
Wagner A. Information theory, evolutionary innovations and evolvability. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372. PMID 29061889 DOI: 10.1098/Rstb.2016.0416 |
0.308 |
|
| 2017 |
Aguilar-Rodríguez J, Payne JL, Wagner A. A thousand empirical adaptive landscapes and their navigability. Nature Ecology & Evolution. 1: 45. PMID 28812623 DOI: 10.1038/S41559-016-0045 |
0.77 |
|
| 2017 |
Hosseini SR, Wagner A. Constraint and Contingency Pervade the Emergence of Novel Phenotypes in Complex Metabolic Systems. Biophysical Journal. 113: 690-701. PMID 28793223 DOI: 10.1016/J.Bpj.2017.06.034 |
0.328 |
|
| 2017 |
Chu HY, Sprouffske K, Wagner A. The role of recombination in evolutionary adaptation of Escherichia coli to a novel nutrient. Journal of Evolutionary Biology. PMID 28612351 DOI: 10.1111/Jeb.13132 |
0.381 |
|
| 2017 |
Bratulic S, Toll-Riera M, Wagner A. Mistranslation can enhance fitness through purging of deleterious mutations. Nature Communications. 8: 15410. PMID 28524864 DOI: 10.1038/Ncomms15410 |
0.391 |
|
| 2017 |
Fortuna MA, Zaman L, Ofria C, Wagner A. The genotype-phenotype map of an evolving digital organism. Plos Computational Biology. 13: e1005414. PMID 28241039 DOI: 10.1371/Journal.Pcbi.1005414 |
0.334 |
|
| 2016 |
Wagner A. The White-Knight Hypothesis, or Does the Environment Limit Innovations? Trends in Ecology & Evolution. PMID 27871674 DOI: 10.1016/J.Tree.2016.10.017 |
0.372 |
|
| 2016 |
Hosseini SR, Wagner A. The potential for non-adaptive origins of evolutionary innovations in central carbon metabolism. Bmc Systems Biology. 10: 97. PMID 27769243 DOI: 10.1186/S12918-016-0343-7 |
0.306 |
|
| 2016 |
Hosseini SR, Martin OC, Wagner A. Phenotypic innovation through recombination in genome-scale metabolic networks. Proceedings. Biological Sciences. 283. PMID 27683361 DOI: 10.1098/Rspb.2016.1536 |
0.344 |
|
| 2016 |
Aguilar-Rodríguez J, Sabater-Muñoz B, Montagud-Martínez R, Berlanga V, Alvarez-Ponce D, Wagner A, Fares MA. The molecular chaperone DnaK is a source of mutational robustness. Genome Biology and Evolution. PMID 27497316 DOI: 10.1093/Gbe/Evw176 |
0.784 |
|
| 2016 |
R Vahdati A, Wagner A. Parallel or convergent evolution in human population genomic data revealed by genotype networks. Bmc Evolutionary Biology. 16: 154. PMID 27484992 DOI: 10.1186/S12862-016-0722-0 |
0.344 |
|
| 2016 |
Toll-Riera M, San Millan A, Wagner A, MacLean RC. The Genomic Basis of Evolutionary Innovation in Pseudomonas aeruginosa. Plos Genetics. 12: e1006005. PMID 27149698 DOI: 10.1371/Journal.Pgen.1006005 |
0.404 |
|
| 2016 |
Khalid F, Aguilar-Rodríguez J, Wagner A, Payne JL. Genonets server-a web server for the construction, analysis and visualization of genotype networks. Nucleic Acids Research. PMID 27106055 DOI: 10.1093/Nar/Gkw313 |
0.767 |
|
| 2016 |
Sprouffske K, Aguilar-Rodríguez J, Wagner A. How archiving by freezing affects the genome-scale diversity of Escherichia coli populations. Genome Biology and Evolution. PMID 26988250 DOI: 10.1093/Gbe/Evw054 |
0.766 |
|
| 2016 |
Blattner AC, Aguilar-Rodríguez J, Kränzlin M, Wagner A, Lehner CF. Drosophila Nnf1 paralogs are partially redundant for somatic and germ line kinetochore function. Chromosoma. PMID 26892014 DOI: 10.1007/S00412-016-0579-4 |
0.762 |
|
| 2015 |
Payne JL, Wagner A. Mechanisms of mutational robustness in transcriptional regulation. Frontiers in Genetics. 6: 322. PMID 26579194 DOI: 10.3389/Fgene.2015.00322 |
0.379 |
|
| 2015 |
Hayden EJ, Bendixsen DP, Wagner A. Intramolecular phenotypic capacitance in a modular RNA molecule. Proceedings of the National Academy of Sciences of the United States of America. PMID 26401020 DOI: 10.1073/Pnas.1420902112 |
0.364 |
|
| 2015 |
Bratulic S, Gerber F, Wagner A. Mistranslation drives the evolution of robustness in TEM-1 β-lactamase. Proceedings of the National Academy of Sciences of the United States of America. PMID 26392536 DOI: 10.1073/Pnas.1510071112 |
0.35 |
|
| 2015 |
Bilgin Sonay T, Carvalho T, Robinson MD, Greminger MP, Krützen M, Comas D, Highnam G, Mittelman D, Sharp A, Marques-Bonet T, Wagner A. Tandem repeat variation in human and great ape populations and its impact on gene expression divergence. Genome Research. PMID 26290536 DOI: 10.1101/Gr.190868.115 |
0.371 |
|
| 2015 |
Hosseini SR, Barve A, Wagner A. Exhaustive Analysis of a Genotype Space Comprising 1015 Central Carbon Metabolisms Reveals an Organization Conducive to Metabolic Innovation. Plos Computational Biology. 11: e1004329. PMID 26252881 DOI: 10.1371/Journal.Pcbi.1004329 |
0.315 |
|
| 2015 |
Sabater-Muñoz B, Prats-Escriche M, Montagud-Martínez R, López-Cerdán A, Toft C, Aguilar-Rodríguez J, Wagner A, Fares MA. Fitness trade-offs determine the role of the molecular chaperonin GroEL in buffering mutations. Molecular Biology and Evolution. PMID 26116858 DOI: 10.1093/Molbev/Msv144 |
0.791 |
|
| 2015 |
Wagner A. Causal drift, robust signaling, and complex disease. Plos One. 10: e0118413. PMID 25774510 DOI: 10.1371/Journal.Pone.0118413 |
0.336 |
|
| 2014 |
Dall'Olio GM, Bertranpetit J, Wagner A, Laayouni H. Human genome variation and the concept of genotype networks. Plos One. 9: e99424. PMID 24911413 DOI: 10.1371/Journal.Pone.0099424 |
0.424 |
|
| 2014 |
Payne JL, Wagner A. Latent phenotypes pervade gene regulatory circuits. Bmc Systems Biology. 8: 64. PMID 24884746 DOI: 10.1186/1752-0509-8-64 |
0.398 |
|
| 2014 |
Szövényi P, Devos N, Weston DJ, Yang X, Hock Z, Shaw JA, Shimizu KK, McDaniel SF, Wagner A. Efficient purging of deleterious mutations in plants with haploid selfing. Genome Biology and Evolution. 6: 1238-52. PMID 24879432 DOI: 10.1093/Gbe/Evu099 |
0.34 |
|
| 2014 |
Wagner A. A genotype network reveals homoplastic cycles of convergent evolution in influenza A (H3N2) haemagglutinin. Proceedings. Biological Sciences / the Royal Society. 281. PMID 24827434 DOI: 10.1098/Rspb.2013.2763 |
0.337 |
|
| 2014 |
Barve A, Hosseini SR, Martin OC, Wagner A. Historical contingency and the gradual evolution of metabolic properties in central carbon and genome-scale metabolisms. Bmc Systems Biology. 8: 48. PMID 24758311 DOI: 10.1186/1752-0509-8-48 |
0.32 |
|
| 2014 |
Wagner A. Mutational robustness accelerates the origin of novel RNA phenotypes through phenotypic plasticity. Biophysical Journal. 106: 955-65. PMID 24559998 DOI: 10.1016/J.Bpj.2014.01.003 |
0.345 |
|
| 2014 |
Payne JL, Wagner A. The robustness and evolvability of transcription factor binding sites. Science (New York, N.Y.). 343: 875-7. PMID 24558158 DOI: 10.1126/Science.1249046 |
0.315 |
|
| 2014 |
Dhar R, Bergmiller T, Wagner A. Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes. Evolution; International Journal of Organic Evolution. 68: 1775-91. PMID 24495000 DOI: 10.1111/Evo.12373 |
0.348 |
|
| 2014 |
Hayden EJ, Bratulic S, Koenig I, Ferrada E, Wagner A. The effects of stabilizing and directional selection on phenotypic and genotypic variation in a population of RNA enzymes. Journal of Molecular Evolution. 78: 101-8. PMID 24309994 DOI: 10.1007/S00239-013-9604-X |
0.339 |
|
| 2014 |
Payne JL, Moore JH, Wagner A. Robustness, evolvability, and the logic of genetic regulation. Artificial Life. 20: 111-26. PMID 23373974 DOI: 10.1162/Artl_A_00099 |
0.347 |
|
| 2013 |
Barve A, Wagner A. A latent capacity for evolutionary innovation through exaptation in metabolic systems. Nature. 500: 203-6. PMID 23851393 DOI: 10.1038/Nature12301 |
0.324 |
|
| 2013 |
Bilgin T, Kurnaz IA, Wagner A. Selection shapes the robustness of ligand-binding amino acids. Journal of Molecular Evolution. 76: 343-9. PMID 23689513 DOI: 10.1007/S00239-013-9564-1 |
0.307 |
|
| 2013 |
Szövényi P, Ricca M, Hock Z, Shaw JA, Shimizu KK, Wagner A. Selection is no more efficient in haploid than in diploid life stages of an angiosperm and a moss. Molecular Biology and Evolution. 30: 1929-39. PMID 23686659 DOI: 10.1093/Molbev/Mst095 |
0.366 |
|
| 2013 |
Sabath N, Ferrada E, Barve A, Wagner A. Growth temperature and genome size in bacteria are negatively correlated, suggesting genomic streamlining during thermal adaptation. Genome Biology and Evolution. 5: 966-77. PMID 23563968 DOI: 10.1093/Gbe/Evt050 |
0.308 |
|
| 2013 |
Dhar R, Sägesser R, Weikert C, Wagner A. Yeast adapts to a changing stressful environment by evolving cross-protection and anticipatory gene regulation. Molecular Biology and Evolution. 30: 573-88. PMID 23125229 DOI: 10.1093/Molbev/Mss253 |
0.324 |
|
| 2013 |
Bichsel M, Barbour AD, Wagner A. Estimating the fitness effect of an insertion sequence. Journal of Mathematical Biology. 66: 95-114. PMID 22252506 DOI: 10.1007/S00285-012-0504-2 |
0.323 |
|
| 2012 |
Hayden EJ, Weikert C, Wagner A. Directional selection causes decanalization in a group I ribozyme. Plos One. 7: e45351. PMID 23028955 DOI: 10.1371/Journal.Pone.0045351 |
0.385 |
|
| 2012 |
Wagner A. Metabolic networks and their evolution. Advances in Experimental Medicine and Biology. 751: 29-52. PMID 22821452 DOI: 10.1007/978-1-4614-3567-9_2 |
0.352 |
|
| 2012 |
Sabath N, Wagner A, Karlin D. Evolution of viral proteins originated de novo by overprinting. Molecular Biology and Evolution. 29: 3767-80. PMID 22821011 DOI: 10.1093/Molbev/Mss179 |
0.366 |
|
| 2012 |
Ferrada E, Wagner A. A comparison of genotype-phenotype maps for RNA and proteins. Biophysical Journal. 102: 1916-25. PMID 22768948 DOI: 10.1016/J.Bpj.2012.01.047 |
0.305 |
|
| 2012 |
Hayden EJ, Wagner A. Environmental change exposes beneficial epistatic interactions in a catalytic RNA. Proceedings. Biological Sciences / the Royal Society. 279: 3418-25. PMID 22719036 DOI: 10.1098/Rspb.2012.0956 |
0.363 |
|
| 2012 |
Barve A, Rodrigues JF, Wagner A. Superessential reactions in metabolic networks. Proceedings of the National Academy of Sciences of the United States of America. 109: E1121-30. PMID 22509034 DOI: 10.1073/Pnas.1113065109 |
0.329 |
|
| 2012 |
Guo B, Zou M, Wagner A. Pervasive indels and their evolutionary dynamics after the fish-specific genome duplication. Molecular Biology and Evolution. 29: 3005-22. PMID 22490820 DOI: 10.1093/Molbev/Mss108 |
0.384 |
|
| 2012 |
Bragg JG, Quigg A, Raven JA, Wagner A. Protein elemental sparing and codon usage bias are correlated among bacteria. Molecular Ecology. 21: 2480-7. PMID 22439830 DOI: 10.1111/J.1365-294X.2012.05529.X |
0.329 |
|
| 2012 |
Chen B, Wagner A. Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations. Bmc Evolutionary Biology. 12: 25. PMID 22369091 DOI: 10.1186/1471-2148-12-25 |
0.341 |
|
| 2012 |
Hyberts SG, Milbradt AG, Wagner AB, Arthanari H, Wagner G. Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling. Journal of Biomolecular Nmr. 52: 315-27. PMID 22331404 DOI: 10.1007/s10858-012-9611-z |
0.368 |
|
| 2012 |
Wagner A. The role of robustness in phenotypic adaptation and innovation. Proceedings. Biological Sciences / the Royal Society. 279: 1249-58. PMID 22217723 DOI: 10.1098/Rspb.2011.2293 |
0.391 |
|
| 2012 |
Wagner A, Weikert C. Phenotypic Constraints and Phenotypic Hitchhiking in a Promiscuous Enzyme The Open Evolution Journal. 6: 14-28. DOI: 10.2174/1874404401206010014 |
0.344 |
|
| 2012 |
Wagner A. The Role of Randomness in Darwinian Evolution Philosophy of Science. 79: 95-119. DOI: 10.1086/663239 |
0.36 |
|
| 2011 |
Wagner A. The molecular origins of evolutionary innovations. Trends in Genetics : Tig. 27: 397-410. PMID 21872964 DOI: 10.1016/J.Tig.2011.06.002 |
0.362 |
|
| 2011 |
Samal A, Wagner A, Martin OC. Environmental versatility promotes modularity in genome-scale metabolic networks. Bmc Systems Biology. 5: 135. PMID 21864340 DOI: 10.1186/1752-0509-5-135 |
0.338 |
|
| 2011 |
Wagner A. Genotype networks shed light on evolutionary constraints. Trends in Ecology & Evolution. 26: 577-84. PMID 21840080 DOI: 10.1016/J.Tree.2011.07.001 |
0.375 |
|
| 2011 |
Hayden EJ, Ferrada E, Wagner A. Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme. Nature. 474: 92-5. PMID 21637259 DOI: 10.1038/Nature10083 |
0.396 |
|
| 2011 |
Wagner A. The low cost of recombination in creating novel phenotypes: Recombination can create new phenotypes while disrupting well-adapted phenotypes much less than mutation. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 33: 636-46. PMID 21633964 DOI: 10.1002/Bies.201100027 |
0.39 |
|
| 2011 |
Espinosa-Soto C, Martin OC, Wagner A. Phenotypic robustness can increase phenotypic variability after nongenetic perturbations in gene regulatory circuits. Journal of Evolutionary Biology. 24: 1284-1297. PMID 21443645 DOI: 10.1111/J.1420-9101.2011.02261.X |
0.407 |
|
| 2011 |
Matias Rodrigues JF, Wagner A. Genotype networks, innovation, and robustness in sulfur metabolism. Bmc Systems Biology. 5: 39. PMID 21385333 DOI: 10.1186/1752-0509-5-39 |
0.325 |
|
| 2011 |
Dhar R, Sägesser R, Weikert C, Yuan J, Wagner A. Adaptation of Saccharomyces cerevisiae to saline stress through laboratory evolution. Journal of Evolutionary Biology. 24: 1135-53. PMID 21375649 DOI: 10.1111/J.1420-9101.2011.02249.X |
0.361 |
|
| 2011 |
Raman K, Wagner A. Evolvability and robustness in a complex signalling circuit. Molecular Biosystems. 7: 1081-92. PMID 21225054 DOI: 10.1039/C0Mb00165A |
0.332 |
|
| 2011 |
Espinosa-Soto C, Martin OC, Wagner A. Phenotypic plasticity can facilitate adaptive evolution in gene regulatory circuits Bmc Evolutionary Biology. 11: 5-5. PMID 21211007 DOI: 10.1186/1471-2148-11-5 |
0.37 |
|
| 2011 |
Raman K, Wagner A. The evolvability of programmable hardware. Journal of the Royal Society, Interface / the Royal Society. 8: 269-81. PMID 20534598 DOI: 10.1098/Rsif.2010.0212 |
0.315 |
|
| 2010 |
Ferrada E, Wagner A. Evolutionary Innovations and the Organization of Protein Functions in Genotype Space Plos One. 5. PMID 21152394 DOI: 10.1371/Journal.Pone.0014172 |
0.339 |
|
| 2010 |
Sulc P, Wagner A, Martin OC. Quantifying slow evolutionary dynamics in RNA fitness landscapes. Journal of Bioinformatics and Computational Biology. 8: 1027-1040. PMID 21121025 DOI: 10.1142/S0219720010005075 |
0.315 |
|
| 2010 |
Rankin DJ, Bichsel M, Wagner A. Mobile DNA can drive lineage extinction in prokaryotic populations. Journal of Evolutionary Biology. 23: 2422-2431. PMID 20860700 DOI: 10.1111/J.1420-9101.2010.02106.X |
0.313 |
|
| 2010 |
Espinosa-Soto C, Wagner A. Specialization Can Drive the Evolution of Modularity Plos Computational Biology. 6. PMID 20360969 DOI: 10.1371/Journal.Pcbi.1000719 |
0.343 |
|
| 2010 |
Samal A, Matias Rodrigues JF, Jost J, Martin OC, Wagner A. Genotype networks in metabolic reaction spaces. Bmc Systems Biology. 4: 30. PMID 20302636 DOI: 10.1186/1752-0509-4-30 |
0.325 |
|
| 2009 |
Rodrigues JFM, Wagner A. Evolutionary plasticity and innovations in complex metabolic reaction networks. Plos Computational Biology. 5. PMID 20019795 DOI: 10.1371/Journal.Pcbi.1000613 |
0.398 |
|
| 2009 |
Wagner A. Evolutionary constraints permeate large metabolic networks Bmc Evolutionary Biology. 9: 231-231. PMID 19747381 DOI: 10.1186/1471-2148-9-231 |
0.301 |
|
| 2009 |
Chaux Ndl, Wagner A. Evolutionary dynamics of the LTR retrotransposons roo and rooA inferred from twelve complete Drosophila genomes Bmc Evolutionary Biology. 9: 205-205. PMID 19689787 DOI: 10.1186/1471-2148-9-205 |
0.323 |
|
| 2009 |
Martin OC, Wagner A. Effects of Recombination on Complex Regulatory Circuits Genetics. 183: 673-684. PMID 19652184 DOI: 10.1534/Genetics.109.104174 |
0.387 |
|
| 2009 |
Bragg JG, Wagner A. Protein material costs: single atoms can make an evolutionary difference. Trends in Genetics : Tig. 25: 5-8. PMID 19010565 DOI: 10.1016/J.Tig.2008.10.007 |
0.325 |
|
| 2008 |
Jörg T, Martin OC, Wagner A. Neutral network sizes of biological RNA molecules can be computed and are not atypically small Bmc Bioinformatics. 9: 464-464. PMID 18973652 DOI: 10.1186/1471-2105-9-464 |
0.345 |
|
| 2008 |
Wagner A. Neutralism and selectionism: a network-based reconciliation. Nature Reviews Genetics. 9: 965-974. PMID 18957969 DOI: 10.1038/Nrg2473 |
0.419 |
|
| 2008 |
Wagner A, Chaux Ndl. Distant horizontal gene transfer is rare for multiple families of prokaryotic insertion sequences. Molecular Genetics and Genomics. 280: 397-408. PMID 18751731 DOI: 10.1007/S00438-008-0373-Y |
0.304 |
|
| 2008 |
Wright J, Wagner A. Exhaustive identification of steady state cycles in large stoichiometric networks Bmc Systems Biology. 2: 61-61. PMID 18616835 DOI: 10.1186/1752-0509-2-61 |
0.317 |
|
| 2008 |
Ferrada E, Wagner A. Protein robustness promotes evolutionary innovations on large evolutionary time-scales. Proceedings of the Royal Society B: Biological Sciences. 275: 1595-1602. PMID 18430649 DOI: 10.1098/Rspb.2007.1617 |
0.348 |
|
| 2008 |
Martin OC, Wagner A. Multifunctionality and Robustness Trade-Offs in Model Genetic Circuits Biophysical Journal. 94: 2927-2937. PMID 18367655 DOI: 10.1529/Biophysj.107.114348 |
0.359 |
|
| 2008 |
Wagner A. Gene duplications, robustness and evolutionary innovations. Bioessays. 30: 367-373. PMID 18348184 DOI: 10.1002/Bies.20728 |
0.388 |
|
| 2008 |
Wagner A. Robustness and evolvability: a paradox resolved. Proceedings of the Royal Society B: Biological Sciences. 275: 91-100. PMID 17971325 DOI: 10.1098/Rspb.2007.1137 |
0.422 |
|
| 2008 |
Félix M, Wagner A. Robustness and evolution: concepts, insights and challenges from a developmental model system. Heredity. 100: 132-140. PMID 17167519 DOI: 10.1038/Sj.Hdy.6800915 |
0.328 |
|
| 2007 |
Ciliberti S, Martin OC, Wagner A. Innovation and robustness in complex regulatory gene networks Proceedings of the National Academy of Sciences of the United States of America. 104: 13591-13596. PMID 17690244 DOI: 10.1073/Pnas.0705396104 |
0.369 |
|
| 2007 |
Wagner A, Lewis C, Bichsel M. A survey of bacterial insertion sequences using IScan. Nucleic Acids Research. 35: 5284-93. PMID 17686783 DOI: 10.1093/Nar/Gkm597 |
0.314 |
|
| 2007 |
Wagner A. From bit to it: how a complex metabolic network transforms information into living matter. Bmc Systems Biology. 1: 33-33. PMID 17663759 DOI: 10.1186/1752-0509-1-33 |
0.313 |
|
| 2007 |
Wagner A. Rapid detection of positive selection in genes and genomes through variation clusters. Genetics. 176: 2451-2463. PMID 17603100 DOI: 10.1534/Genetics.107.074732 |
0.357 |
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| 2007 |
Sumedha, Martin OC, Wagner A. New structural variation in evolutionary searches of RNA neutral networks. Biosystems. 90: 475-485. PMID 17276586 DOI: 10.1016/J.Biosystems.2006.11.007 |
0.327 |
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| 2007 |
Ciliberti S, Martin OC, Wagner A. Robustness can evolve gradually in complex regulatory gene networks with varying topology. Plos Computational Biology. 3. PMID 17274682 DOI: 10.1371/Journal.Pcbi.0030015 |
0.344 |
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| 2007 |
Bragg JG, Wagner A. Protein carbon content evolves in response to carbon availability and may influence the fate of duplicated genes. Proceedings. Biological Sciences / the Royal Society. 274: 1063-70. PMID 17264057 DOI: 10.1098/Rspb.2006.0290 |
0.325 |
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| 2007 |
Wagner A. Energy costs constrain the evolution of gene expression. Journal of Experimental Zoology. 308: 322-324. PMID 17262826 DOI: 10.1002/Jez.B.21152 |
0.348 |
|
| 2007 |
Wagner A, Wright J. Alternative routes and mutational robustness in complex regulatory networks. Biosystems. 88: 163-172. PMID 16860925 DOI: 10.1016/J.Biosystems.2006.06.002 |
0.347 |
|
| 2006 |
Vitkup D, Kharchenko P, Wagner A. Influence of metabolic network structure and function on enzyme evolution. Genome Biology. 7: R39. PMID 16684370 DOI: 10.1186/Gb-2006-7-5-R39 |
0.366 |
|
| 2006 |
Wagner A. Periodic Extinctions of Transposable Elements in Bacterial Lineages: Evidence from Intragenomic Variation in Multiple Genomes Molecular Biology and Evolution. 23: 723-733. PMID 16373392 DOI: 10.1093/Molbev/Msj085 |
0.341 |
|
| 2005 |
Conant GC, Wagner A. The rarity of gene shuffling in conserved genes. Genome Biology. 6: R50. PMID 15960802 DOI: 10.1186/Gb-2005-6-6-R50 |
0.634 |
|
| 2005 |
Wagner A. Robustness, evolvability, and neutrality. Febs Letters. 579: 1772-1778. PMID 15763550 DOI: 10.1016/J.Febslet.2005.01.063 |
0.364 |
|
| 2005 |
Wagner A. Energy Constraints on the Evolution of Gene Expression Molecular Biology and Evolution. 22: 1365-1374. PMID 15758206 DOI: 10.1093/Molbev/Msi126 |
0.332 |
|
| 2005 |
Wagner A. Distributed robustness versus redundancy as causes of mutational robustness. Bioessays. 27: 176-188. PMID 15666345 DOI: 10.1002/Bies.20170 |
0.423 |
|
| 2004 |
Berg J, Lässig M, Wagner A. Structure and evolution of protein interaction networks: a statistical model for link dynamics and gene duplications. Bmc Evolutionary Biology. 4: 51. PMID 15566577 DOI: 10.1186/1471-2148-4-51 |
0.355 |
|
| 2004 |
Evangelisti AM, Wagner A. Molecular evolution in the yeast transcriptional regulation network. Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution. 302: 392-411. PMID 15287103 DOI: 10.1002/Jez.B.20027 |
0.348 |
|
| 2004 |
Conant GC, Wagner A. A fast algorithm for determining the best combination of local alignments to a query sequence. Bmc Bioinformatics. 5: 62. PMID 15149555 DOI: 10.1186/1471-2105-5-62 |
0.594 |
|
| 2004 |
Wagner A. Reconstructing Pathways in Large Genetic Networks from Genetic Perturbations Journal of Computational Biology. 11: 53-60. PMID 15072688 DOI: 10.1089/106652704773416885 |
0.358 |
|
| 2004 |
Tringe SG, Wagner A, Ruby SW. Enriching for direct regulatory targets in perturbed gene-expression profiles. Genome Biology. 5: R29. PMID 15059262 DOI: 10.1186/Gb-2004-5-4-R29 |
0.322 |
|
| 2004 |
Hahn MW, Conant GC, Wagner A. Molecular evolution in large genetic networks: does connectivity equal constraint? Journal of Molecular Evolution. 58: 203-11. PMID 15042341 DOI: 10.1007/S00239-003-2544-0 |
0.669 |
|
| 2004 |
Conant GC, Wagner A. Duplicate genes and robustness to transient gene knock-downs in Caenorhabditis elegans. Proceedings. Biological Sciences. 271: 89-96. PMID 15002776 DOI: 10.1098/Rspb.2003.2560 |
0.652 |
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| 2003 |
de Visser JA, Hermisson J, Wagner GP, Ancel Meyers L, Bagheri-Chaichian H, Blanchard JL, Chao L, Cheverud JM, Elena SF, Fontana W, Gibson G, Hansen TF, Krakauer D, Lewontin RC, Ofria C, ... ... Wagner A, et al. Perspective: Evolution and detection of genetic robustness. Evolution; International Journal of Organic Evolution. 57: 1959-72. PMID 14575319 DOI: 10.1554/02-750R |
0.764 |
|
| 2003 |
Wagner A. Does Selection Mold Molecular Networks Science Signaling. 2003. PMID 14519859 DOI: 10.1126/Stke.2003.202.Pe41 |
0.318 |
|
| 2003 |
Conant GC, Wagner A. Asymmetric sequence divergence of duplicate genes. Genome Research. 13: 2052-8. PMID 12952876 DOI: 10.1101/Gr.1252603 |
0.658 |
|
| 2003 |
Conant GC, Wagner A. Convergent evolution of gene circuits. Nature Genetics. 34: 264-6. PMID 12819781 DOI: 10.1038/Ng1181 |
0.645 |
|
| 2003 |
Wagner A. How the global structure of protein interaction networks evolves Proceedings of the Royal Society B: Biological Sciences. 270: 457-466. PMID 12641899 DOI: 10.1098/Rspb.2002.2269 |
0.35 |
|
| 2003 |
Conant GC, Plimpton SJ, Old W, Wagner A, Fain PR, Pacheco TR, Heffelfinger G. Parallel Genehunter: implementation of a linkage analysis package for distributed-memory architectures Journal of Parallel and Distributed Computing. 63: 674-682. DOI: 10.1016/S0743-7315(03)00080-7 |
0.581 |
|
| 2002 |
Wagner A. Asymmetric Functional Divergence of Duplicate Genes in Yeast Molecular Biology and Evolution. 19: 1760-1768. PMID 12270902 DOI: 10.1093/Oxfordjournals.Molbev.A003998 |
0.4 |
|
| 2002 |
Conant GC, Wagner A. GenomeHistory: a software tool and its application to fully sequenced genomes. Nucleic Acids Research. 30: 3378-86. PMID 12140322 DOI: 10.1093/Nar/Gkf449 |
0.634 |
|
| 2002 |
Wagner A. Selection and gene duplication: a view from the genome Genome Biology. 3: 1-3. PMID 12049669 DOI: 10.1186/Gb-2002-3-5-Reviews1012 |
0.344 |
|
| 2002 |
Wagner A. Estimating Coarse Gene Network Structure from Large-Scale Gene Perturbation Data Genome Research. 12: 309-315. PMID 11827950 DOI: 10.1101/Gr.193902 |
0.341 |
|
| 2002 |
Wagner A. The large-scale structure of metabolic networks: a glimpse at life's origin? Complexity. 8: 15-19. DOI: 10.1002/Cplx.10046 |
0.307 |
|
| 2001 |
Wagner A. How to reconstruct a large genetic network from n gene perturbations in fewer than n2 easy steps Bioinformatics. 17: 1183-1197. PMID 11751227 DOI: 10.1093/Bioinformatics/17.12.1183 |
0.362 |
|
| 2001 |
Wagner A, Fell DA. The small world inside large metabolic networks. Proceedings. Biological Sciences / the Royal Society. 268: 1803-10. PMID 11522199 DOI: 10.1098/Rspb.2001.1711 |
0.315 |
|
| 2001 |
Wagner A. The Yeast Protein Interaction Network Evolves Rapidly and Contains Few Redundant Duplicate Genes Molecular Biology and Evolution. 18: 1283-1292. PMID 11420367 DOI: 10.1093/Oxfordjournals.Molbev.A003913 |
0.33 |
|
| 2001 |
Wagner A. Birth and death of duplicated genes in completely sequenced eukaryotes Trends in Genetics. 17: 237-239. PMID 11335019 DOI: 10.1016/S0168-9525(01)02243-0 |
0.328 |
|
| 2001 |
GLEISS PM, STADLER PF, WAGNER A, FELL DA. RELEVANT CYCLES IN CHEMICAL REACTION NETWORKS Advances in Complex Systems. 4: 207-226. DOI: 10.1142/S0219525901000140 |
0.456 |
|
| 2000 |
Wagner A. Inferring Lifestyle from Gene Expression Patterns Molecular Biology and Evolution. 17: 1985-1987. PMID 11110914 DOI: 10.1093/Oxfordjournals.Molbev.A026299 |
0.37 |
|
| 2000 |
Wagner A. Decoupled evolution of coding region and mRNA expression patterns after gene duplication: Implications for the neutralist-selectionist debate Proceedings of the National Academy of Sciences of the United States of America. 97: 6579-6584. PMID 10823904 DOI: 10.1073/Pnas.110147097 |
0.341 |
|
| 2000 |
Wagner A. Robustness against mutations in genetic networks of yeast. Nature Genetics. 24: 355-361. PMID 10742097 DOI: 10.1038/74174 |
0.423 |
|
| 1999 |
Wagner A. Genes regulated cooperatively by one or more transcription factors and their identification in whole eukaryotic genomes. Bioinformatics. 15: 776-784. PMID 10705431 DOI: 10.1093/Bioinformatics/15.10.776 |
0.302 |
|
| 1999 |
Wagner A, Stadler PF. Viral RNA and evolved mutational robustness. The Journal of Experimental Zoology. 285: 119-27. PMID 10440723 DOI: 10.1002/(Sici)1097-010X(19990815)285:2<119::Aid-Jez4>3.0.Co;2-D |
0.515 |
|
| 1998 |
Wagner A. The fate of duplicated genes: loss or new function? Bioessays. 20: 785-788. PMID 10200118 DOI: 10.1002/(Sici)1521-1878(199810)20:10<785::Aid-Bies2>3.0.Co;2-M |
0.39 |
|
| 1998 |
Wagner A. Distribution of transcription factor binding sites in the yeast genome suggests abundance of coordinately regulated genes. Genomics. 50: 293-295. PMID 9653659 DOI: 10.1006/Geno.1998.5303 |
0.302 |
|
| 1997 |
Wagner A. A computational genomics approach to the identification of gene networks Nucleic Acids Research. 25: 3594-3604. PMID 9278479 DOI: 10.1093/Nar/25.18.3594 |
0.333 |
|
| 1996 |
Wagner A. Does Evolutionary Plasticity Evolve Evolution. 50: 1008-1023. PMID 28565284 DOI: 10.1111/J.1558-5646.1996.Tb02342.X |
0.381 |
|
| 1996 |
Wagner A. Genetic redundancy caused by gene duplications and its evolution in networks of transcriptional regulators Biological Cybernetics. 74: 557-567. PMID 8672563 DOI: 10.1007/Bf00209427 |
0.401 |
|
| 1996 |
Wagner A. Can nonlinear epigenetic interactions obscure causal relations between genotype and phenotype Nonlinearity. 9: 607-629. DOI: 10.1088/0951-7715/9/3/001 |
0.394 |
|
| 1994 |
Wagner A. Evolution of gene networks by gene duplications: a mathematical model and its implications on genome organization. Proceedings of the National Academy of Sciences of the United States of America. 91: 4387-91. PMID 8183919 DOI: 10.1073/Pnas.91.10.4387 |
0.356 |
|
| 1994 |
Wagner A, Wagner GP, Similion P. Epistasis can facilitate the evolution of reproductive isolation by peak shifts: a two-locus two-allele model. Genetics. 138: 533-45. PMID 7828834 |
0.437 |
|
| 1994 |
Wagner A, Blackstone N, Cartwright P, Dick M, Misof B, Snow P, Wagner GP, Bartels J, Murtha M, Pendleton J. Surveys of Gene Families Using Polymerase Chain Reaction: PCR Selection and PCR Drift Systematic Biology. 43: 250-261. DOI: 10.1093/Sysbio/43.2.250 |
0.466 |
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