| Year |
Citation |
Score |
| 2023 |
Miller ET, Tsodikov OV, Garneau-Tsodikova S. Structural insights into the diverse prenylating capabilities of DMATS prenyltransferases. Natural Product Reports. PMID 37929638 DOI: 10.1039/d3np00036b |
0.601 |
|
| 2023 |
Pang AH, Green KD, Tsodikov OV, Garneau-Tsodikova S. Discovery and development of inhibitors of acetyltransferase Eis to combat Mycobacterium tuberculosis. Methods in Enzymology. 690: 369-396. PMID 37858535 DOI: 10.1016/bs.mie.2023.06.017 |
0.758 |
|
| 2023 |
Haldar J, Garneau-Tsodikova S, Fridman M. Introduction to the themed collection on antimicrobial resistance. Rsc Medicinal Chemistry. 14: 1398-1399. PMID 37593571 DOI: 10.1039/d3md90016a |
0.547 |
|
| 2023 |
Chiasson S, Smith T, Bello L, Chandrika NT, Green KD, Garneau-Tsodikova S, Thompson MK. Small molecule inhibitors of the fosfomycin resistance enzyme FosM from Mycobacterium abscessus. Biochimica Et Biophysica Acta. General Subjects. 1867: 130444. PMID 37579984 DOI: 10.1016/j.bbagen.2023.130444 |
0.614 |
|
| 2023 |
Thamban Chandrika N, Green KD, Spencer AC, Tsodikov OV, Garneau-Tsodikova S. Discovery and development of novel substituted monohydrazides as potent antifungal agents. Rsc Medicinal Chemistry. 14: 1351-1361. PMID 37484566 DOI: 10.1039/d3md00167a |
0.705 |
|
| 2023 |
Travis S, Green KD, Thamban Chandrika N, Pang AH, Frantom PA, Tsodikov OV, Garneau-Tsodikova S, Thompson MK. Identification and analysis of small molecule inhibitors of FosB from . Rsc Medicinal Chemistry. 14: 947-956. PMID 37252104 DOI: 10.1039/d3md00113j |
0.766 |
|
| 2023 |
Gelzinis JA, Szahaj MK, Bekendam RH, Wurl SE, Pantos MM, Verbetsky CA, Dufresne A, Shea M, Howard KC, Tsodikov OV, Garneau-Tsodikova S, Zwicker JI, Kennedy DR. Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e22914. PMID 37043381 DOI: 10.1096/fj.202201952R |
0.542 |
|
| 2023 |
Green KD, Thamban Chandrika N, Vu LY, Pang AH, Tsodikov OV, Garneau-Tsodikova S. Aromatic hydrazides: A potential solution for Acinetobacter baumannii infections. European Journal of Medicinal Chemistry. 249: 115165. PMID 36739749 DOI: 10.1016/j.ejmech.2023.115165 |
0.735 |
|
| 2023 |
Pang AH, Green KD, Punetha A, Thamban Chandrika N, Howard KC, Garneau-Tsodikova S, Tsodikov OV. Discovery and Mechanistic Analysis of Structurally Diverse Inhibitors of Acetyltransferase Eis among FDA-Approved Drugs. Biochemistry. 62: 710-721. PMID 36657084 DOI: 10.1021/acs.biochem.2c00658 |
0.738 |
|
| 2022 |
Travis S, Green KD, Gilbert NC, Tsodikov OV, Garneau-Tsodikova S, Thompson MK. Inhibition of Fosfomycin Resistance Protein FosB from Gram-Positive Pathogens by Phosphonoformate. Biochemistry. PMID 36525630 DOI: 10.1021/acs.biochem.2c00566 |
0.767 |
|
| 2022 |
Pang AH, Green KD, Chandrika NT, Garzan A, Punetha A, Holbrook SYL, Willby MJ, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity. European Journal of Medicinal Chemistry. 242: 114698. PMID 36037791 DOI: 10.1016/j.ejmech.2022.114698 |
0.827 |
|
| 2022 |
Green KD, Pang AH, Thamban Chandrika N, Garzan A, Baughn AD, Tsodikov OV, Garneau-Tsodikova S. Discovery and Optimization of 6-(1-Substituted pyrrole-2-yl)--triazine Containing Compounds as Antibacterial Agents. Acs Infectious Diseases. 8: 757-767. PMID 35239306 DOI: 10.1021/acsinfecdis.1c00450 |
0.809 |
|
| 2021 |
Behnsen J, Zhi H, Aron AT, Subramanian V, Santus W, Lee MH, Gerner RR, Petras D, Liu JZ, Green KD, Price SL, Camacho J, Hillman H, Tjokrosurjo J, Montaldo NP, ... ... Garneau-Tsodikova S, et al. Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut. Nature Communications. 12: 7016. PMID 34853318 DOI: 10.1038/s41467-021-27297-2 |
0.599 |
|
| 2021 |
Punetha A, Green KD, Garzan A, Thamban Chandrika N, Willby MJ, Pang AH, Hou C, Holbrook SYL, Krieger K, Posey JE, Parish T, Tsodikov OV, Garneau-Tsodikova S. Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from to overcome kanamycin resistance. Rsc Medicinal Chemistry. 12: 1894-1909. PMID 34825186 DOI: 10.1039/d1md00239b |
0.827 |
|
| 2021 |
Kim SK, Ngo HX, Dennis EK, Thamban Chandrika N, DeShong P, Garneau-Tsodikova S, Lee VT. Inhibition of Alginate Synthesis by Ebselen Oxide and Its Analogues. Acs Infectious Diseases. PMID 33871968 DOI: 10.1021/acsinfecdis.1c00045 |
0.601 |
|
| 2021 |
Green KD, Punetha A, Chandrika NT, Hou C, Garneau-Tsodikova S, Tsodikov OV. Development of single-stranded DNA bisintercalating inhibitors of primase DnaG as antibiotics. Chemmedchem. PMID 33711198 DOI: 10.1002/cmdc.202100001 |
0.745 |
|
| 2020 |
Taylor IR, Assimon VA, Kuo SY, Rinaldi S, Li X, Young ZT, Morra G, Green K, Nguyen D, Shao H, Garneau-Tsodikova S, Colombo G, Gestwicki JE. Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells. Chemical Science. 11: 1892-1904. PMID 34123282 DOI: 10.1039/c9sc04284a |
0.603 |
|
| 2020 |
Howard KC, Gonzalez OA, Garneau-Tsodikova S. Second Generation of Zafirlukast Derivatives with Improved Activity against the Oral Pathogen . Acs Medicinal Chemistry Letters. 11: 1905-1912. PMID 33062172 DOI: 10.1021/Acsmedchemlett.9B00614 |
0.376 |
|
| 2020 |
Mori S, Garneau-Tsodikova S, Tsodikov OV. Unimodular Methylation by Adenylation-Thiolation Domains Containing an Embedded Methyltransferase. Journal of Molecular Biology. PMID 32920052 DOI: 10.1016/J.Jmb.2020.09.004 |
0.608 |
|
| 2020 |
Punetha A, Ngo HX, Holbrook SYL, Green KD, Willby MJ, Bonnett SA, Krieger K, Dennis EK, Posey JE, Parish T, Tsodikov OV, Garneau-Tsodikova S. Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis from . Acs Chemical Biology. PMID 32421305 DOI: 10.1021/Acschembio.0C00184 |
0.767 |
|
| 2020 |
Howard KC, Dennis EK, Watt DS, Garneau-Tsodikova S. A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise. Chemical Society Reviews. PMID 32140691 DOI: 10.1039/C9Cs00556K |
0.354 |
|
| 2020 |
Ying L, Zhu H, Fosso MY, Garneau-Tsodikova S, Fredrick K. Modified Aminoglycosides Bind Nucleic Acids in High-Molecular-Weight Complexes. Antibiotics (Basel, Switzerland). 9. PMID 32098020 DOI: 10.3390/Antibiotics9020093 |
0.346 |
|
| 2020 |
Taylor IR, Assimon VA, Kuo SY, Rinaldi S, Li X, Young ZT, Morra G, Green K, Nguyen D, Shao H, Garneau-Tsodikova S, Colombo G, Gestwicki JE. Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells Chemical Science. 11: 1892-1904. DOI: 10.1039/C9Sc04284A |
0.609 |
|
| 2019 |
Thamban Chandrika N, Fosso MY, Tsodikov OV, LeVine Iii H, Garneau-Tsodikova S. Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Aβ Fibril Assembly. Molecules (Basel, Switzerland). 25. PMID 31878304 DOI: 10.3390/Molecules25010077 |
0.629 |
|
| 2019 |
Dennis EK, Kim JH, Parkin S, Awuah SG, Garneau-Tsodikova S. Distorted Gold(I)-Phosphine Complexes as Antifungal Agents. Journal of Medicinal Chemistry. PMID 31841324 DOI: 10.1021/Acs.Jmedchem.9B01436 |
0.377 |
|
| 2019 |
Sarkar A, Garneau-Tsodikova S. Resisting resistance: gearing up for war. Medchemcomm. 10: 1512-1516. PMID 31803398 DOI: 10.1039/C9Md00330D |
0.363 |
|
| 2019 |
Green KD, Punetha A, Hou C, Garneau-Tsodikova S, Tsodikov OV. Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis. Acs Infectious Diseases. PMID 31433614 DOI: 10.1021/Acsinfecdis.9B00228 |
0.78 |
|
| 2019 |
Thamban Chandrika N, Fosso MY, Alimova Y, May A, Gonzalez OA, Garneau-Tsodikova S. Novel zafirlukast derivatives exhibit selective antibacterial activity against . Medchemcomm. 10: 926-933. PMID 31303990 DOI: 10.1039/C9Md00074G |
0.345 |
|
| 2019 |
Mori S, Pang AH, Chandrika NT, Garneau-Tsodikova S, Tsodikov OV. Publisher Correction: Unusual substrate and halide versatility of phenolic halogenase PltM. Nature Communications. 10: 2053. PMID 31040284 DOI: 10.1038/S41467-019-09731-8 |
0.554 |
|
| 2019 |
Mori S, Pang AH, Thamban Chandrika N, Garneau-Tsodikova S, Tsodikov OV. Unusual substrate and halide versatility of phenolic halogenase PltM. Nature Communications. 10: 1255. PMID 30890712 DOI: 10.1038/s41467-019-09215-9 |
0.63 |
|
| 2019 |
Green KD, Fosso MY, Mayhoub AS, Garneau-Tsodikova S. Investigating the promiscuity of the chloramphenicol nitroreductase from Haemophilus influenzae towards the reduction of 4-nitrobenzene derivatives. Bioorganic & Medicinal Chemistry Letters. PMID 30826292 DOI: 10.1016/J.Bmcl.2019.02.025 |
0.622 |
|
| 2018 |
Thamban Chandrika N, Dennis EK, Shrestha SK, Ngo HX, Green KD, Kwiatkowski S, Deaciuc AG, Dwoskin LP, Watt DS, Garneau-Tsodikova S. N,N'-diaryl-bishydrazones in a biphenyl platform: Broad spectrum antifungal agents. European Journal of Medicinal Chemistry. 164: 273-281. PMID 30597328 DOI: 10.1016/J.Ejmech.2018.12.042 |
0.546 |
|
| 2018 |
Green KD, Fosso MY, Garneau-Tsodikova S. Multifunctional Donepezil Analogues as Cholinesterase and BACE1 Inhibitors. Molecules (Basel, Switzerland). 23. PMID 30544832 DOI: 10.3390/Molecules23123252 |
0.594 |
|
| 2018 |
Story S, Skriba MJ, Maiti K, Nihar Ranjan, Degtyareva NN, Green KD, Khodaverdian V, Oyelere AK, Garneau-Tsodikova S, Arya DP. Synthesis, antimicrobial activity, attenuation of aminoglycoside resistance in MRSA, and ribosomal A-site binding of pyrene-neomycin conjugates. European Journal of Medicinal Chemistry. 163: 381-393. PMID 30530174 DOI: 10.1016/J.Ejmech.2018.11.022 |
0.65 |
|
| 2018 |
Dennis EK, Garneau-Tsodikova S. Synergistic combinations of azoles and antihistamines against Candida species in vitro. Medical Mycology. PMID 30295881 DOI: 10.1093/Mmy/Myy088 |
0.372 |
|
| 2018 |
Scutigliani EM, Scholl ER, Grootemaat AE, Khanal S, Kochan JA, Krawczyk PM, Reits EA, Garzan A, Ngo HX, Green KD, Garneau-Tsodikova S, Ruijter JM, van Veen HA, van der Wel NN. Interfering With DNA Decondensation as a Strategy Against Mycobacteria. Frontiers in Microbiology. 9: 2034. PMID 30233521 DOI: 10.3389/Fmicb.2018.02034 |
0.798 |
|
| 2018 |
Holbrook SYL, Gentry MS, Tsodikov OV, Garneau-Tsodikova S. Nucleoside triphosphate cosubstrates control the substrate profile and efficiency of aminoglycoside 3'--phosphotransferase type IIa. Medchemcomm. 9: 1332-1339. PMID 30151088 DOI: 10.1039/C8Md00234G |
0.644 |
|
| 2018 |
Mori S, Green KD, Choi R, Buchko GW, Fried MG, Garneau-Tsodikova S. Using MbtH-like proteins to alter substrate profile of a nonribosomal peptide adenylation enzyme. Chembiochem : a European Journal of Chemical Biology. PMID 30134012 DOI: 10.1002/Cbic.201800240 |
0.55 |
|
| 2018 |
Louzoun Zada S, Green KD, Shrestha SK, Herzog IM, Garneau-Tsodikova S, Fridman M. Derivatives of Ribosome-Inhibiting Antibiotic Chloramphenicol Inhibit the Biosynthesis of Bacterial Cell Wall. Acs Infectious Diseases. PMID 29714997 DOI: 10.1021/Acsinfecdis.8B00078 |
0.712 |
|
| 2018 |
Fosso MY, Shrestha SK, Thamban Chandrika N, Dennis EK, Green KD, Garneau-Tsodikova S. Differential Effects of Linkers on the Activity of Amphiphilic Tobramycin Antifungals. Molecules (Basel, Switzerland). 23. PMID 29652845 DOI: 10.3390/Molecules23040899 |
0.611 |
|
| 2018 |
Ngo HX, Green KD, Gajadeera CS, Willby MJ, Holbrook SYL, Hou C, Garzan A, Mayhoub AS, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Potent 1,2,4-Triazino[5,6 b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 29601176 DOI: 10.1021/Acsinfecdis.8B00074 |
0.826 |
|
| 2018 |
Mori S, Pang AH, Lundy TA, Garzan A, Tsodikov OV, Garneau-Tsodikova S. Structural basis for backbone N-methylation by an interrupted adenylation domain. Nature Chemical Biology. PMID 29556104 DOI: 10.1038/S41589-018-0014-7 |
0.794 |
|
| 2018 |
Lundy TA, Mori S, Garneau-Tsodikova S. Engineering Bifunctional Enzymes Capable of Adenylating and Selectively Methylating the Side Chain or Core of Amino Acids. Acs Synthetic Biology. PMID 29393631 DOI: 10.1021/Acssynbio.7B00426 |
0.327 |
|
| 2018 |
Green KD, Biswas T, Pang AH, Willby MJ, Reed MS, Stuchlik O, Pohl J, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight. Biochemistry. PMID 29345920 DOI: 10.1021/Acs.Biochem.7B01089 |
0.72 |
|
| 2018 |
Thamban Chandrika N, Garneau-Tsodikova S. Comprehensive review of chemical strategies for the preparation of new aminoglycosides and their biological activities. Chemical Society Reviews. PMID 29296992 DOI: 10.1039/C7Cs00407A |
0.368 |
|
| 2017 |
Thamban Chandrika N, Shrestha SK, Ngo HX, Howard KC, Garneau-Tsodikova S. Novel fluconazole derivatives with promising antifungal activity. Bioorganic & Medicinal Chemistry. PMID 29279242 DOI: 10.1016/J.Bmc.2017.12.018 |
0.432 |
|
| 2017 |
Holbrook SYL, Garneau-Tsodikova S. Evaluation of Aminoglycoside and Carbapenem Resistance in a Collection of Drug-Resistant Pseudomonas aeruginosa Clinical Isolates. Microbial Drug Resistance (Larchmont, N.Y.). PMID 29261405 DOI: 10.1089/Mdr.2017.0101 |
0.38 |
|
| 2017 |
Thamban Chandrika N, Shrestha SK, Ngo HX, Tsodikov OV, Howard KC, Garneau-Tsodikova S. Alkylated Piperazines and Piperazine-Azole Hybrids as Antifungal Agents. Journal of Medicinal Chemistry. PMID 29256601 DOI: 10.1021/Acs.Jmedchem.7B01138 |
0.678 |
|
| 2017 |
Thamban Chandrika N, Shrestha SK, Ranjan N, Sharma A, Arya DP, Garneau-Tsodikova S. New Application of Neomycin B-Bisbenzimidazole Hybrids as Antifungal Agents. Acs Infectious Diseases. PMID 29227087 DOI: 10.1021/Acsinfecdis.7B00254 |
0.373 |
|
| 2017 |
Mori S, Garzan A, Tsodikov OV, Garneau-Tsodikova S. Deciphering Nature's Intricate Way of N,S-Dimethylating l-Cysteine: Sequential Action of Two Bifunctional Adenylation Domains. Biochemistry. PMID 29112395 DOI: 10.1021/Acs.Biochem.7B00980 |
0.789 |
|
| 2017 |
Holbrook SYL, Garzan A, Dennis EK, Shrestha SK, Garneau-Tsodikova S. Repurposing antipsychotic drugs into antifungal agents: Synergistic combinations of azoles and bromperidol derivatives in the treatment of various fungal infections. European Journal of Medicinal Chemistry. 139: 12-21. PMID 28797882 DOI: 10.1016/J.Ejmech.2017.07.030 |
0.758 |
|
| 2017 |
Mori S, Shrestha SK, Fernández J, Álvarez San Millán M, Garzan A, Al-Mestarihi AH, Lombó F, Garneau-Tsodikova S. Activation and loading of the starter unit during thiocoraline biosynthesis. Biochemistry. PMID 28762729 DOI: 10.1021/Acs.Biochem.7B00661 |
0.78 |
|
| 2017 |
Shrestha SK, Garzan A, Garneau-Tsodikova S. Novel alkylated azoles as potent antifungals. European Journal of Medicinal Chemistry. 133: 309-318. PMID 28395217 DOI: 10.1016/J.Ejmech.2017.03.075 |
0.778 |
|
| 2017 |
Garzan A, Willby MJ, Ngo HX, Gajadeera CS, Green KD, Holbrook SY, Hou C, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Combating Eis-mediated kanamycin resistance of M. tuber-culosis by novel pyrrolo[1,5-a]pyrazine-based Eis inhibitors. Acs Infectious Diseases. PMID 28192916 DOI: 10.1021/Acsinfecdis.6B00193 |
0.826 |
|
| 2017 |
Degtyareva NN, Gong C, Story S, Levinson N, Oyelere AK, Green KD, Garneau-Tsodikova S, Arya DP. Antimicrobial Activity, AME Resistance and Translation Inhibition Studies of Anthraquinone-Neomycin Conjugates. Acs Infectious Diseases. PMID 28103015 DOI: 10.1021/Acsinfecdis.6B00176 |
0.654 |
|
| 2017 |
Pang AH, Garneau-Tsodikova S, Tsodikov OV. In Vitro Assays to Identify Antibiotics Targeting DNA Metabolism. Methods in Molecular Biology (Clifton, N.J.). 1520: 175-200. PMID 27873253 DOI: 10.1007/978-1-4939-6634-9_11 |
0.613 |
|
| 2016 |
Garzan A, Willby MJ, Green KD, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant M. tuberculosis. Acs Medicinal Chemistry Letters. 7: 1219-1221. PMID 27994767 DOI: 10.1021/Acsmedchemlett.6B00261 |
0.812 |
|
| 2016 |
Garzan A, Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 59: 10619-10628. PMID 27933949 DOI: 10.1021/Acs.Jmedchem.6B01161 |
0.82 |
|
| 2016 |
Shrestha SK, Kril LM, Green KD, Kwiatkowski S, Sviripa VM, Nickell JR, Dwoskin LP, Watt DS, Garneau-Tsodikova S. Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. Bioorganic & Medicinal Chemistry. PMID 27769670 DOI: 10.1016/J.Bmc.2016.10.009 |
0.634 |
|
| 2016 |
Ngo HX, Garneau-Tsodikova S, Green KD. A complex game of hide and seek: the search for new antifungals. Medchemcomm. 7: 1285-1306. PMID 27766140 DOI: 10.1039/C6Md00222F |
0.582 |
|
| 2016 |
Pang AH, Garzan A, Larsen MJ, McQuade TJ, Garneau-Tsodikova S, Tsodikov OV. Discovery of allosteric and selective inhibitors of inorganic pyrophosphatase from Mycobacterium tuberculosis. Acs Chemical Biology. PMID 27622287 DOI: 10.1021/Acschembio.6B00510 |
0.824 |
|
| 2016 |
Holbrook SY, Garneau-Tsodikova S. Expanding aminoglycoside resistance enzyme regiospecificity by mutation and truncation. Biochemistry. PMID 27618454 DOI: 10.1021/Acs.Biochem.6B00770 |
0.412 |
|
| 2016 |
McKeating KS, Couture M, Dinel MP, Garneau-Tsodikova S, Masson JF. High throughput LSPR and SERS analysis of aminoglycoside antibiotics. The Analyst. PMID 27412506 DOI: 10.1039/C6An00540C |
0.318 |
|
| 2016 |
Ngo HX, Garneau-Tsodikova S. Flipping the Switch "On" for Aminoglycoside-Resistance Enzymes: The Mechanism Is Finally Revealed! Structure (London, England : 1993). 24: 1011-3. PMID 27387794 DOI: 10.1016/J.Str.2016.06.006 |
0.398 |
|
| 2016 |
Piddock L, Garneau-Tsodikova S, Garner C. Ask the experts: how to curb antibiotic resistance and plug the antibiotics gap? Future Medicinal Chemistry. PMID 27327784 DOI: 10.4155/Fmc-2014-0032 |
0.357 |
|
| 2016 |
Chandrika NT, Shrestha SK, Ngo HX, Garneau-Tsodikova S. Synthesis and investigation of novel benzimidazole derivatives as antifungal agents. Bioorganic & Medicinal Chemistry. PMID 27301676 DOI: 10.1016/J.Bmc.2016.06.010 |
0.394 |
|
| 2016 |
Ngo HX, Shrestha SK, Green KD, Garneau-Tsodikova S. Development of ebsulfur analogues as potent antibacterials against methicillin-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry. PMID 27073054 DOI: 10.1016/J.Bmc.2016.03.060 |
0.647 |
|
| 2016 |
Liu X, Jin Y, Cai W, Green KD, Goswami A, Garneau-Tsodikova S, Nonaka K, Baba S, Funabashi M, Yang Z, Van Lanen SG. A biocatalytic approach to capuramycin analogues by exploiting a substrate permissive N-transacylase CapW. Organic & Biomolecular Chemistry. PMID 27050157 DOI: 10.1039/C6Ob00381H |
0.652 |
|
| 2016 |
Chandrika NT, Garneau-Tsodikova S. A review of patents (2011-2015) towards combating resistance to and toxicity of aminoglycosides. Medchemcomm. 7: 50-68. PMID 27019689 DOI: 10.1039/C5Md00453E |
0.353 |
|
| 2016 |
Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Potent inhibitors of acetyltransferase Eis overcome kanamycin re-sistance in Mycobacterium tuberculosis. Acs Chemical Biology. PMID 27010218 DOI: 10.1021/Acschembio.6B00110 |
0.774 |
|
| 2016 |
Garneau-Tsodikova S, Labby KJ. Mechanisms of Resistance to Aminoglycoside Antibiotics: Overview and Perspectives. Medchemcomm. 7: 11-27. PMID 26877861 DOI: 10.1039/C5Md00344J |
0.381 |
|
| 2016 |
Jin Y, Watkins D, Degtyareva NN, Green KD, Spano MN, Garneau-Tsodikova S, Arya DP. Arginine-linked neomycin B dimers: synthesis, rRNA binding, and resistance enzyme activity. Medchemcomm. 7: 164-169. PMID 26811742 DOI: 10.1039/C5Md00427F |
0.644 |
|
| 2016 |
Ngo HX, Garneau-Tsodikova S, Green KD. A complex game of hide and seek: The search for new antifungals Medchemcomm. 7: 1285-1306. DOI: 10.1039/c6md00222f |
0.538 |
|
| 2016 |
Garneau-Tsodikova S, Wright GD. Antibiotic Resistance themed issue Medchemcomm. 7: 10. DOI: 10.1039/C5Md90063H |
0.543 |
|
| 2015 |
Green KD, Pricer RE, Stewart MN, Garneau-Tsodikova S. Comparative Study of Eis-like Enzymes from Pathogenic and Nonpathogenic Bacteria. Acs Infectious Diseases. 1: 272-83. PMID 27622743 DOI: 10.1021/Acsinfecdis.5B00036 |
0.669 |
|
| 2015 |
Assimon VA, Shao H, Garneau-Tsodikova S, Gestwicki JE. Concise Synthesis of Spergualin-Inspired Molecules With Broad-Spectrum Antibiotic Activity. Medchemcomm. 6: 912-918. PMID 27087913 DOI: 10.1039/C4Md00572D |
0.402 |
|
| 2015 |
Thamban Chandrika N, Green KD, Houghton JL, Garneau-Tsodikova S. Synthesis and Biological Activity of Mono- and Di-N-acylated Aminoglycosides. Acs Medicinal Chemistry Letters. 6: 1134-1139. PMID 26617967 DOI: 10.1021/Acsmedchemlett.5B00255 |
0.63 |
|
| 2015 |
Fosso MY, Shrestha SK, Green KD, Garneau-Tsodikova S. Synthesis and bioactivities of kanamycin B-derived cationic amphiphiles. Journal of Medicinal Chemistry. PMID 26592740 DOI: 10.1021/Acs.Jmedchem.5B01375 |
0.654 |
|
| 2015 |
Pang AH, Garneau-Tsodikova S, Tsodikov OV. Crystal structure of halogenase PltA from the pyoluteorin biosynthetic pathway. Journal of Structural Biology. PMID 26416533 DOI: 10.1016/J.Jsb.2015.09.013 |
0.643 |
|
| 2015 |
Fosso MY, LeVine H, Green KD, Tsodikov OV, Garneau-Tsodikova S. Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones. Organic & Biomolecular Chemistry. 13: 9418-26. PMID 26248214 DOI: 10.1039/C5Ob01478F |
0.711 |
|
| 2015 |
Wasserman MR, Pulk A, Zhou Z, Altman RB, Zinder JC, Green KD, Garneau-Tsodikova S, Doudna Cate JH, Blanchard SC. Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions. Nature Communications. 6: 7896. PMID 26224058 DOI: 10.1038/Ncomms8896 |
0.567 |
|
| 2015 |
Tsodikov OV, Hou C, Walsh CT, Garneau-Tsodikova S. Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: a case of challenging structure determination at low resolution. Bmc Structural Biology. 15: 13. PMID 26170207 DOI: 10.1186/S12900-015-0040-6 |
0.68 |
|
| 2015 |
Shrestha SK, Fosso MY, Green KD, Garneau-Tsodikova S. Amphiphilic Tobramycin Analogues as Antibacterial and Antifungal Agents. Antimicrobial Agents and Chemotherapy. 59: 4861-9. PMID 26033722 DOI: 10.1128/Aac.00229-15 |
0.596 |
|
| 2015 |
Fosso MY, Zhu H, Green KD, Garneau-Tsodikova S, Fredrick K. Tobramycin Variants with Enhanced Ribosome-Targeting Activity. Chembiochem : a European Journal of Chemical Biology. 16: 1565-70. PMID 26033429 DOI: 10.1002/Cbic.201500256 |
0.635 |
|
| 2015 |
Al-Mestarihi AH, Garzan A, Kim JM, Garneau-Tsodikova S. Enzymatic Evidence for a Revised Congocidine Biosynthetic Pathway. Chembiochem : a European Journal of Chemical Biology. 16: 1307-13. PMID 25958990 DOI: 10.1002/Cbic.201402711 |
0.795 |
|
| 2015 |
Li Y, Green KD, Johnson BR, Garneau-Tsodikova S. Inhibition of Aminoglycoside Acetyltransferase Resistance Enzymes by Metal Salts. Antimicrobial Agents and Chemotherapy. 59: 4148-56. PMID 25941215 DOI: 10.1128/Aac.00885-15 |
0.624 |
|
| 2015 |
Green KD, Biswas T, Chang C, Wu R, Chen W, Janes BK, Chalupska D, Gornicki P, Hanna PC, Tsodikov OV, Joachimiak A, Garneau-Tsodikova S. Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis. Biochemistry. 54: 3197-206. PMID 25928210 DOI: 10.1021/Acs.Biochem.5B00244 |
0.756 |
|
| 2015 |
Watkins D, Kumar S, Green KD, Arya DP, Garneau-Tsodikova S. Influence of Linker Length and Composition on Enzymatic Activity and Ribosomal Binding of Neomycin Dimers. Antimicrobial Agents and Chemotherapy. 59: 3899-905. PMID 25896697 DOI: 10.1128/Aac.00861-15 |
0.618 |
|
| 2015 |
Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, et al. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. The Journal of Biological Chemistry. 290: 13710-24. PMID 25855790 DOI: 10.1074/Jbc.M115.646414 |
0.605 |
|
| 2015 |
Jiang L, Watkins D, Jin Y, Gong C, King A, Washington AZ, Green KD, Garneau-Tsodikova S, Oyelere AK, Arya DP. Rapid synthesis, RNA binding, and antibacterial screening of a peptidic-aminosugar (PA) library. Acs Chemical Biology. 10: 1278-89. PMID 25706406 DOI: 10.1021/Cb5010367 |
0.61 |
|
| 2015 |
Labby KJ, Watsula SG, Garneau-Tsodikova S. Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis. Natural Product Reports. 32: 641-53. PMID 25622971 DOI: 10.1039/C4Np00120F |
0.341 |
|
| 2015 |
Gajadeera C, Willby MJ, Green KD, Shaul P, Fridman M, Garneau-Tsodikova S, Posey JE, Tsodikov OV. Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG. The Journal of Antibiotics. 68: 153-7. PMID 25248725 DOI: 10.1038/Ja.2014.131 |
0.811 |
|
| 2015 |
Blacher E, Ben Baruch B, Levy A, Geva N, Green KD, Garneau-Tsodikova S, Fridman M, Stein R. Inhibition of glioma progression by a newly discovered CD38 inhibitor. International Journal of Cancer. Journal International Du Cancer. 136: 1422-33. PMID 25053177 DOI: 10.1002/Ijc.29095 |
0.661 |
|
| 2015 |
Blacher E, Levy A, Baruch BB, Green KD, Garneau-Tsodikova S, Fridman M, Stein R. Targeting CD38 in the tumor microenvironment: A novel approach to treat glioma Cancer Cell & Microenvironment. 2. DOI: 10.14800/Ccm.486 |
0.652 |
|
| 2015 |
Tsodikov OV, Hou C, Walsh CT, Garneau-Tsodikova S. Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: A case of challenging structure determination at low resolution Bmc Structural Biology. 15. DOI: 10.1186/s12900-015-0040-6 |
0.603 |
|
| 2015 |
Fosso MY, LeVine H, Green KD, Tsodikov OV, Garneau-Tsodikova S. Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones Organic and Biomolecular Chemistry. 13: 9418-9426. DOI: 10.1039/c5ob01478f |
0.69 |
|
| 2014 |
Al-Mestarihi AH, Villamizar G, Fernández J, Zolova OE, Lombó F, Garneau-Tsodikova S. Adenylation and S-methylation of cysteine by the bifunctional enzyme TioN in thiocoraline biosynthesis. Journal of the American Chemical Society. 136: 17350-4. PMID 25409494 DOI: 10.1021/Ja510489J |
0.78 |
|
| 2014 |
Fosso MY, Li Y, Garneau-Tsodikova S. New trends in aminoglycosides use. Medchemcomm. 5: 1075-1091. PMID 25071928 DOI: 10.1039/C4Md00163J |
0.321 |
|
| 2014 |
Tsodikov OV, Green KD, Garneau-Tsodikova S. A random sequential mechanism of aminoglycoside acetylation by Mycobacterium tuberculosis Eis protein. Plos One. 9: e92370. PMID 24699000 DOI: 10.1371/Journal.Pone.0092370 |
0.76 |
|
| 2014 |
Zolova OE, Garneau-Tsodikova S. KtzJ-dependent serine activation and O-methylation by KtzH for kutznerides biosynthesis. The Journal of Antibiotics. 67: 59-64. PMID 24105608 DOI: 10.1038/Ja.2013.98 |
0.339 |
|
| 2013 |
Houghton JL, Biswas T, Chen W, Tsodikov OV, Garneau-Tsodikova S. Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis. Chembiochem : a European Journal of Chemical Biology. 14: 2127-35. PMID 24106131 DOI: 10.1002/Cbic.201300359 |
0.685 |
|
| 2013 |
Biswas T, Green KD, Garneau-Tsodikova S, Tsodikov OV. Discovery of inhibitors of Bacillus anthracis primase DnaG. Biochemistry. 52: 6905-10. PMID 24004110 DOI: 10.1021/Bi4011286 |
0.751 |
|
| 2013 |
Green KD, Garneau-Tsodikova S. Resistance in tuberculosis: what do we know and where can we go? Frontiers in Microbiology. 4: 208. PMID 23888158 DOI: 10.3389/Fmicb.2013.00208 |
0.628 |
|
| 2013 |
Labby KJ, Garneau-Tsodikova S. Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections. Future Medicinal Chemistry. 5: 1285-309. PMID 23859208 DOI: 10.4155/Fmc.13.80 |
0.433 |
|
| 2013 |
Jennings BC, Labby KJ, Green KD, Garneau-Tsodikova S. Redesign of substrate specificity and identification of the aminoglycoside binding residues of Eis from Mycobacterium tuberculosis. Biochemistry. 52: 5125-32. PMID 23837529 DOI: 10.1021/Bi4002985 |
0.629 |
|
| 2013 |
Berkov-Zrihen Y, Green KD, Labby KJ, Feldman M, Garneau-Tsodikova S, Fridman M. Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. Journal of Medicinal Chemistry. 56: 5613-25. PMID 23786357 DOI: 10.1021/Jm400707F |
0.745 |
|
| 2013 |
Eckroat TJ, Green KD, Reed RA, Bornstein JJ, Garneau-Tsodikova S. Investigation of the role of linker moieties in bifunctional tacrine hybrids. Bioorganic & Medicinal Chemistry. 21: 3614-23. PMID 23535563 DOI: 10.1016/J.Bmc.2013.02.047 |
0.607 |
|
| 2013 |
Green KD, Garneau-Tsodikova S. Domain dissection and characterization of the aminoglycoside resistance enzyme ANT(3″)-Ii/AAC(6')-IId from Serratia marcescens. Biochimie. 95: 1319-25. PMID 23485681 DOI: 10.1016/J.Biochi.2013.02.011 |
0.637 |
|
| 2013 |
Houghton JL, Green KD, Pricer RE, Mayhoub AS, Garneau-Tsodikova S. Unexpected N-acetylation of capreomycin by mycobacterial Eis enzymes. The Journal of Antimicrobial Chemotherapy. 68: 800-5. PMID 23233486 DOI: 10.1093/Jac/Dks497 |
0.645 |
|
| 2013 |
Kochi A, Eckroat TJ, Green KD, Mayhoub AS, Lim MH, Garneau-Tsodikova S. A novel hybrid of 6-chlorotacrine and metal-amyloid-β modulator for inhibition of acetylcholinesterase and metal-induced amyloid-β aggregation Chemical Science. 4: 4137-4145. DOI: 10.1039/C3Sc51902C |
0.541 |
|
| 2013 |
Houghton JL, Biswas T, Chen W, Tsodikov OV, Garneau-Tsodikova S. Cover Picture: Chemical and Structural Insights into the Regioversatility of the Aminoglycoside Acetyltransferase Eis (ChemBioChem 16/2013) Chembiochem. 14: 2061-2061. DOI: 10.1002/cbic.201390058 |
0.547 |
|
| 2012 |
Pricer RE, Houghton JL, Green KD, Mayhoub AS, Garneau-Tsodikova S. Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilis. Molecular Biosystems. 8: 3305-13. PMID 23090428 DOI: 10.1039/C2Mb25341K |
0.611 |
|
| 2012 |
Chen W, Green KD, Garneau-Tsodikova S. Cosubstrate tolerance of the aminoglycoside resistance enzyme Eis from Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 56: 5831-8. PMID 22948873 DOI: 10.1128/Aac.00932-12 |
0.641 |
|
| 2012 |
Chen W, Green KD, Tsodikov OV, Garneau-Tsodikova S. Aminoglycoside multiacetylating activity of the enhanced intracellular survival protein from Mycobacterium smegmatis and its inhibition. Biochemistry. 51: 4959-67. PMID 22646013 DOI: 10.1021/Bi3004473 |
0.756 |
|
| 2012 |
Herzog IM, Green KD, Berkov-Zrihen Y, Feldman M, Vidavski RR, Eldar-Boock A, Satchi-Fainaro R, Eldar A, Garneau-Tsodikova S, Fridman M. 6''-Thioether tobramycin analogues: towards selective targeting of bacterial membranes. Angewandte Chemie (International Ed. in English). 51: 5652-6. PMID 22499286 DOI: 10.1002/Anie.201200761 |
0.707 |
|
| 2012 |
Biswas T, Houghton JL, Garneau-Tsodikova S, Tsodikov OV. The structural basis for substrate versatility of chloramphenicol acetyltransferase CATI. Protein Science : a Publication of the Protein Society. 21: 520-30. PMID 22294317 DOI: 10.1002/Pro.2036 |
0.659 |
|
| 2012 |
Green KD, Chen W, Garneau-Tsodikova S. Identification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosis. Chemmedchem. 7: 73-7. PMID 21898832 DOI: 10.1002/Cmdc.201100332 |
0.617 |
|
| 2012 |
Garneau-Tsodikova S, Walsh CT. Editorial: Natural products themed issue Medchemcomm. 3: 852-853. DOI: 10.1039/C2Md90031A |
0.38 |
|
| 2012 |
Zolova OE, Garneau-Tsodikova S. Importance of the MbtH-like protein TioT for production and activation of the thiocoraline adenylation domain of TioK Medchemcomm. 3: 950-955. DOI: 10.1039/C2Md20131C |
0.387 |
|
| 2012 |
Herzog IM, Green KD, Berkov-Zrihen Y, Feldman M, Vidavski RR, Eldar-Boock A, Satchi-Fainaro R, Eldar A, Garneau-Tsodikova S, Fridman M. Innentitelbild: 6′′-Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes (Angew. Chem. 23/2012) Angewandte Chemie. 124: 5602-5602. DOI: 10.1002/Ange.201203240 |
0.638 |
|
| 2011 |
Chen W, Biswas T, Porter VR, Tsodikov OV, Garneau-Tsodikova S. Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB. Proceedings of the National Academy of Sciences of the United States of America. 108: 9804-8. PMID 21628583 DOI: 10.1073/Pnas.1105379108 |
0.669 |
|
| 2011 |
Green KD, Chen W, Garneau-Tsodikova S. Effects of altering aminoglycoside structures on bacterial resistance enzyme activities. Antimicrobial Agents and Chemotherapy. 55: 3207-13. PMID 21537023 DOI: 10.1128/Aac.00312-11 |
0.656 |
|
| 2011 |
Mady AS, Zolova OE, Millán MÁ, Villamizar G, de la Calle F, Lombó F, Garneau-Tsodikova S. Characterization of TioQ, a type II thioesterase from the thiocoraline biosynthetic cluster. Molecular Biosystems. 7: 1999-2011. PMID 21483938 DOI: 10.1039/C1Mb05044C |
0.654 |
|
| 2011 |
Shaul P, Green KD, Rutenberg R, Kramer M, Berkov-Zrihen Y, Breiner-Goldstein E, Garneau-Tsodikova S, Fridman M. Assessment of 6'- and 6'''-N-acylation of aminoglycosides as a strategy to overcome bacterial resistance. Organic & Biomolecular Chemistry. 9: 4057-63. PMID 21365081 DOI: 10.1039/C0Ob01133A |
0.723 |
|
| 2011 |
Bornstein JJ, Eckroat TJ, Houghton JL, Jones CK, Green KD, Garneau-Tsodikova S. Tacrine-mefenamic acid hybrids for inhibition of acetylcholinesterase Medchemcomm. 2: 406-412. DOI: 10.1039/C0Md00256A |
0.586 |
|
| 2010 |
Porter VR, Green KD, Zolova OE, Houghton JL, Garneau-Tsodikova S. Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT(4'). Biochemical and Biophysical Research Communications. 403: 85-90. PMID 21040710 DOI: 10.1016/J.Bbrc.2010.10.119 |
0.659 |
|
| 2010 |
Zolova OE, Mady AS, Garneau-Tsodikova S. Recent developments in bisintercalator natural products. Biopolymers. 93: 777-90. PMID 20578002 DOI: 10.1002/Bip.21489 |
0.372 |
|
| 2010 |
Green KD, Porter VR, Zhang Y, Garneau-Tsodikova S. Redesign of cosubstrate specificity and identification of important residues for substrate binding to hChAT. Biochemistry. 49: 6219-27. PMID 20560540 DOI: 10.1021/Bi1007996 |
0.605 |
|
| 2010 |
Houghton JL, Green KD, Chen W, Garneau-Tsodikova S. The future of aminoglycosides: the end or renaissance? Chembiochem : a European Journal of Chemical Biology. 11: 880-902. PMID 20397253 DOI: 10.1002/Cbic.200900779 |
0.555 |
|
| 2010 |
Biswas T, Zolova OE, Lombó F, de la Calle F, Salas JA, Tsodikov OV, Garneau-Tsodikova S. A new scaffold of an old protein fold ensures binding to the bisintercalator thiocoraline. Journal of Molecular Biology. 397: 495-507. PMID 20122935 DOI: 10.1016/J.Jmb.2010.01.053 |
0.765 |
|
| 2010 |
Green KD, Chen W, Houghton JL, Fridman M, Garneau-Tsodikova S. Exploring the substrate promiscuity of drug-modifying enzymes for the chemoenzymatic generation of N-acylated aminoglycosides. Chembiochem : a European Journal of Chemical Biology. 11: 119-26. PMID 19899089 DOI: 10.1002/Cbic.200900584 |
0.697 |
|
| 2010 |
Green KD, Garneau-Tsodikova S. Posttranslational modification of proteins Comprehensive Natural Products Ii: Chemistry and Biology. 5: 433-468. |
0.476 |
|
| 2009 |
Green KD, Fridman M, Garneau-Tsodikova S. hChAT: a tool for the chemoenzymatic generation of potential acetyl/butyrylcholinesterase inhibitors. Chembiochem : a European Journal of Chemical Biology. 10: 2191-4. PMID 19637146 DOI: 10.1002/Cbic.200900309 |
0.66 |
|
| 2009 |
Li MH, Ung PM, Zajkowski J, Garneau-Tsodikova S, Sherman DH. Automated genome mining for natural products. Bmc Bioinformatics. 10: 185. PMID 19531248 DOI: 10.1186/1471-2105-10-185 |
0.326 |
|
| 2009 |
Garneau-Tsodikova S, Shkel IA, Tsodikov OV. Exact and user-friendly kinetic analysis of the two-step rapid equilibrium Michaelis-Menten mechanism. Analytical Biochemistry. 387: 276-9. PMID 19344659 DOI: 10.1016/J.Ab.2009.01.023 |
0.589 |
|
| 2009 |
McQuade TJ, Shallop AD, Sheoran A, Delproposto JE, Tsodikov OV, Garneau-Tsodikova S. A nonradioactive high-throughput assay for screening and characterization of adenylation domains for nonribosomal peptide combinatorial biosynthesis. Analytical Biochemistry. 386: 244-50. PMID 19135023 DOI: 10.1016/J.Ab.2008.12.014 |
0.636 |
|
| 2008 |
Garneau-Tsodikova S, Thannickal VJ. Protein kinase inhibitors in the treatment of pulmonary fibrosis. Current Medicinal Chemistry. 15: 2632-40. PMID 18855683 DOI: 10.2174/092986708785908969 |
0.303 |
|
| 2008 |
Martin-Visscher LA, van Belkum MJ, Garneau-Tsodikova S, Whittal RM, Zheng J, McMullen LM, Vederas JC. Isolation and characterization of carnocyclin a, a novel circular bacteriocin produced by Carnobacterium maltaromaticum UAL307. Applied and Environmental Microbiology. 74: 4756-63. PMID 18552180 DOI: 10.1128/Aem.00817-08 |
0.77 |
|
| 2008 |
Sheoran A, King A, Velasco A, Pero JM, Garneau-Tsodikova S. Characterization of TioF, a tryptophan 2,3-dioxygenase involved in 3-hydroxyquinaldic acid formation during thiocoraline biosynthesis. Molecular Biosystems. 4: 622-8. PMID 18493661 DOI: 10.1039/B801391H |
0.345 |
|
| 2007 |
Balibar CJ, Garneau-Tsodikova S, Walsh CT. Covalent CouN7 enzyme intermediate for acyl group shuttling in aminocoumarin biosynthesis. Chemistry & Biology. 14: 679-90. PMID 17584615 DOI: 10.1016/J.Chembiol.2007.05.007 |
0.761 |
|
| 2007 |
Fridman M, Balibar CJ, Lupoli T, Kahne D, Walsh CT, Garneau-Tsodikova S. Chemoenzymatic formation of novel aminocoumarin antibiotics by the enzymes CouN1 and CouN7. Biochemistry. 46: 8462-71. PMID 17580964 DOI: 10.1021/Bi700433V |
0.807 |
|
| 2006 |
Ueki M, Galoni? DP, Vaillancourt FH, Garneau-Tsodikova S, Yeh E, Vosburg DA, Schroeder FC, Osada H, Walsh CT. Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete. Chemistry & Biology. 13: 1183-91. PMID 17114000 DOI: 10.1016/J.Chembiol.2006.09.012 |
0.773 |
|
| 2006 |
Dorrestein PC, Bumpus SB, Calderone CT, Garneau-Tsodikova S, Aron ZD, Straight PD, Kolter R, Walsh CT, Kelleher NL. Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry. Biochemistry. 45: 12756-66. PMID 17042494 DOI: 10.1021/Bi061169D |
0.684 |
|
| 2006 |
Garneau-Tsodikova S, Dorrestein PC, Kelleher NL, Walsh CT. Protein assembly line components in prodigiosin biosynthesis: characterization of PigA,G,H,I,J. Journal of the American Chemical Society. 128: 12600-1. PMID 17002325 DOI: 10.1021/Ja063611L |
0.669 |
|
| 2006 |
Vaillancourt FH, Yeh E, Vosburg DA, Garneau-Tsodikova S, Walsh CT. Nature's inventory of halogenation catalysts: oxidative strategies predominate. Chemical Reviews. 106: 3364-78. PMID 16895332 DOI: 10.1021/Cr050313I |
0.728 |
|
| 2006 |
Walsh CT, Garneau-Tsodikova S, Howard-Jones AR. Biological formation of pyrroles: nature's logic and enzymatic machinery. Natural Product Reports. 23: 517-31. PMID 16874387 DOI: 10.1039/B605245M |
0.436 |
|
| 2006 |
Garneau-Tsodikova S, Stapon A, Kahne D, Walsh CT. Installation of the pyrrolyl-2-carboxyl pharmacophore by CouN1 and CouN7 in the late biosynthetic steps of the aminocoumarin antibiotics clorobiocin and coumermycin A1. Biochemistry. 45: 8568-78. PMID 16834331 DOI: 10.1021/Bi060784E |
0.492 |
|
| 2006 |
Dorrestein PC, Blackhall J, Straight PD, Fischbach MA, Garneau-Tsodikova S, Edwards DJ, McLaughlin S, Lin M, Gerwick WH, Kolter R, Walsh CT, Kelleher NL. Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry. Biochemistry. 45: 1537-46. PMID 16460000 DOI: 10.1021/Bi052333K |
0.746 |
|
| 2005 |
Walsh CT, Garneau-Tsodikova S, Gatto GJ. Protein posttranslational modifications: the chemistry of proteome diversifications. Angewandte Chemie (International Ed. in English). 44: 7342-72. PMID 16267872 DOI: 10.1002/Anie.200501023 |
0.371 |
|
| 2005 |
Dorrestein PC, Yeh E, Garneau-Tsodikova S, Kelleher NL, Walsh CT. Dichlorination of a pyrrolyl-S-carrier protein by FADH2-dependent halogenase PltA during pyoluteorin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 102: 13843-8. PMID 16162666 DOI: 10.1073/Pnas.0506964102 |
0.717 |
|
| 2005 |
Walsh CT, Garneau-Tsodikova S, Gatto GJ. Posttranslationale Proteinmodifikation: die Chemie der Proteomdiversifizierung Angewandte Chemie. 117: 7508-7539. DOI: 10.1002/Ange.200501023 |
0.319 |
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