Year |
Citation |
Score |
2014 |
Kuhen KL, Chatterjee AK, Rottmann M, Gagaring K, Borboa R, Buenviaje J, Chen Z, Francek C, Wu T, Nagle A, Barnes SW, Plouffe D, Lee MC, Fidock DA, Graumans W, et al. KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission. Antimicrobial Agents and Chemotherapy. 58: 5060-7. PMID 24913172 DOI: 10.1128/Aac.02727-13 |
0.571 |
|
2012 |
Nagle A, Wu T, Kuhen K, Gagaring K, Borboa R, Francek C, Chen Z, Plouffe D, Lin X, Caldwell C, Ek J, Skolnik S, Liu F, Wang J, Chang J, et al. Imidazolopiperazines: lead optimization of the second-generation antimalarial agents. Journal of Medicinal Chemistry. 55: 4244-73. PMID 22524250 DOI: 10.1021/Jm300041E |
0.551 |
|
2011 |
Meister S, Plouffe DM, Kuhen KL, Bonamy GM, Wu T, Barnes SW, Bopp SE, Borboa R, Bright AT, Che J, Cohen S, Dharia NV, Gagaring K, Gettayacamin M, Gordon P, et al. Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.). 334: 1372-7. PMID 22096101 DOI: 10.1126/Science.1211936 |
0.57 |
|
2011 |
Wu T, Nagle A, Kuhen K, Gagaring K, Borboa R, Francek C, Chen Z, Plouffe D, Goh A, Lakshminarayana SB, Wu J, Ang HQ, Zeng P, Kang ML, Tan W, et al. Imidazolopiperazines: hit to lead optimization of new antimalarial agents. Journal of Medicinal Chemistry. 54: 5116-30. PMID 21644570 DOI: 10.1021/Jm2003359 |
0.59 |
|
2011 |
Wu T, Nagle AS, Chatterjee AK. Road towards new antimalarials - overview of the strategies and their chemical progress. Current Medicinal Chemistry. 18: 853-71. PMID 21182479 DOI: 10.2174/092986711794927748 |
0.533 |
|
2010 |
Deng X, Nagle A, Wu T, Sakata T, Henson K, Chen Z, Kuhen K, Plouffe D, Winzeler E, Adrian F, Tuntland T, Chang J, Simerson S, Howard S, Ek J, et al. Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials. Bioorganic & Medicinal Chemistry Letters. 20: 4027-31. PMID 20610151 DOI: 10.1016/J.Bmcl.2010.05.095 |
0.57 |
|
2009 |
Wu T, Nagle A, Sakata T, Henson K, Borboa R, Chen Z, Kuhen K, Plouffe D, Winzeler E, Adrian F, Tuntland T, Chang J, Simerson S, Howard S, Ek J, et al. Cell-based optimization of novel benzamides as potential antimalarial leads. Bioorganic & Medicinal Chemistry Letters. 19: 6970-4. PMID 19879133 DOI: 10.1016/J.Bmcl.2009.10.050 |
0.552 |
|
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