Dae-Kyun Ro, Ph.D. - Publications

Affiliations: 
2002 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Botany Biology, Biochemistry

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Shahsavarani M, Utomo JC, Kumar R, Paz-Galeano M, Garza-García JJO, Mai Z, Ro DK, Qu Y. Improved protein glycosylation enabled heterologous biosynthesis of monoterpenoid indole alkaloids and their unnatural derivatives in yeast. Metabolic Engineering Communications. 16: e00215. PMID 36569379 DOI: 10.1016/j.mec.2022.e00215  0.319
2022 Jin Z, Ro DK, Kim SU, Kwon M. Piperonal synthase from black pepper () synthesizes a phenolic aroma compound, piperonal, as a CoA-independent catalysis. Applied Biological Chemistry. 65: 20. PMID 35402752 DOI: 10.1186/s13765-022-00691-0  0.326
2020 Sarrade-Loucheur A, Ro DK, Faure R, Remaud-Siméon M, Truan GJ. Synthetic derivatives of (+)-epi-α-bisabolol are formed by mammalian cytochromes P450 expressed in a yeast reconstituted pathway. Acs Synthetic Biology. PMID 31977190 DOI: 10.1021/Acssynbio.9B00399  0.415
2019 Jin Z, Wungsintaweekul J, Kim SH, Kim JH, Shin Y, Ro DK, Kim SU. 4-Coumarate:coenzyme A ligase isoform 3 from Piper nigrum (Pn4CL3) catalyzes the CoA thioester formation of 3,4-methylenedioxycinnamic and piperic acids. The Biochemical Journal. PMID 31764941 DOI: 10.1042/Bcj20190527  0.404
2019 Frey M, Klaiber I, Conrad J, Bersch A, Pateraki I, Ro DK, Spring O. Characterization of CYP71AX36 from Sunflower (Helianthus annuus L., Asteraceae). Scientific Reports. 9: 14295. PMID 31586110 DOI: 10.1038/S41598-019-50520-6  0.402
2019 Nguyen TD, Kwon M, Kim SU, Fischer C, Ro DK. Catalytic plasticity of germacrene A oxidase underlies sesquiterpene lactone diversification. Plant Physiology. PMID 31534022 DOI: 10.1104/Pp.19.00629  0.418
2019 Lakusta AM, Kwon M, Kwon EG, Stonebloom S, Scheller HV, Ro DK. Molecular Studies of the Protein Complexes Involving -Prenyltransferase in Guayule (), an Alternative Rubber-Producing Plant. Frontiers in Plant Science. 10: 165. PMID 30858856 DOI: 10.3389/Fpls.2019.00165  0.374
2018 Lee AR, Kown M, Kang MK, Kim J, Kim SU, Ro DK. Increased sesqui- and triterpene production by co-expression of HMG-CoA reductase and biotin carboxyl carrier protein in tobacco (Nicotiana benthamiana). Metabolic Engineering. PMID 30389612 DOI: 10.1016/J.Ymben.2018.10.008  0.429
2017 Jin Z, Kwon M, Lee AR, Ro DK, Wungsintaweekul J, Kim SU. Molecular cloning and functional characterization of three terpene synthases from unripe fruit of black pepper (Piper nigrum). Archives of Biochemistry and Biophysics. PMID 29248443 DOI: 10.1016/J.Abb.2017.12.011  0.415
2017 Gou J, Hao F, Huang C, Kwon M, Chen F, Li C, Liu C, Ro DK, Tang H, Zhang Y. Discovery of a non-stereoselective cytochrome P450 catalyzing either 8α- or 8β-hydroxylation of germacrene A acid from the Chinese medicinal plant, Inula hupehensis. The Plant Journal : For Cell and Molecular Biology. PMID 29086444 DOI: 10.1111/Tpj.13760  0.322
2017 Hurd MC, Kwon M, Ro DK. Functional identification of a Lippia dulcis bornyl diphosphate synthase that contains a duplicated, inhibitory arginine-rich motif. Biochemical and Biophysical Research Communications. PMID 28655616 DOI: 10.1016/J.Bbrc.2017.06.147  0.39
2017 Liu X, Liu Y, Huang P, Ma Y, Qing Z, Tang Q, Cao H, Cheng P, Zheng Y, Yuan Z, Zhou Y, Liu J, Tang Z, Zhuo Y, Zhang Y, ... ... Ro DK, et al. The genome of the medicinal plant Macleaya cordata provides new insights into benzylisoquinoline alkaloids metabolism. Molecular Plant. PMID 28552780 DOI: 10.1016/J.Molp.2017.05.007  0.351
2016 Zhou Y, Ma Y, Zeng J, Duan L, Xue X, Wang H, Lin T, Liu Z, Zeng K, Zhong Y, Zhang S, Hu Q, Liu M, Zhang H, Reed J, ... ... Ro DK, et al. Convergence and divergence of bitterness biosynthesis and regulation in Cucurbitaceae. Nature Plants. 2: 16183. PMID 27892922 DOI: 10.1038/Nplants.2016.183  0.432
2016 Pelot KA, Mitchell R, Kwon M, Hagelthorn DM, Wardman JF, Chiang A, Bohlmann J, Ro DK, Zerbe P. Biosynthesis of the psychotropic plant diterpene salvinorin A: Discovery and characterization of the Salvia divinorum clerodienyl diphosphate synthase. The Plant Journal : For Cell and Molecular Biology. PMID 27865008 DOI: 10.1111/Tpj.13427  0.398
2016 Nguyen TD, Faraldos JA, Vardakou M, Salmon M, O'Maille PE, Ro DK. Discovery of germacrene A synthases in Barnadesia spinosa: The first committed step in sesquiterpene lactone biosynthesis in the basal member of the Asteraceae. Biochemical and Biophysical Research Communications. PMID 27697527 DOI: 10.1016/J.Bbrc.2016.09.165  0.347
2016 Aschenbrenner AK, Kwon M, Conrad J, Ro DK, Spring O. Identification and characterization of two bisabolene synthases from linear glandular trichomes of sunflower (Helianthus annuus L., Asteraceae). Phytochemistry. PMID 26880289 DOI: 10.1016/J.Phytochem.2016.01.009  0.448
2015 Chakrabarty R, Qu Y, Ro DK. Silencing the lettuce homologs of small rubber particle protein does not influence natural rubber biosynthesis in lettuce (Lactuca sativa). Phytochemistry. 113: 121-9. PMID 25553584 DOI: 10.1016/J.Phytochem.2014.12.003  0.321
2015 Qu Y, Chakrabarty R, Tran HT, Kwon EJ, Kwon M, Nguyen TD, Ro DK. A lettuce (Lactuca sativa) homolog of human Nogo-B receptor interacts with cis-prenyltransferase and is necessary for natural rubber biosynthesis. The Journal of Biological Chemistry. 290: 1898-914. PMID 25477521 DOI: 10.1074/Jbc.M114.616920  0.351
2014 Kwon M, Cochrane SA, Vederas JC, Ro DK. Molecular cloning and characterization of drimenol synthase from valerian plant (Valeriana officinalis). Febs Letters. 588: 4597-603. PMID 25447532 DOI: 10.1016/J.Febslet.2014.10.031  0.43
2014 Son YJ, Kwon M, Ro DK, Kim SU. Enantioselective microbial synthesis of the indigenous natural product (-)-α-bisabolol by a sesquiterpene synthase from chamomile (Matricaria recutita). The Biochemical Journal. 463: 239-48. PMID 25048207 DOI: 10.1042/Bj20140306  0.329
2013 Xiao M, Zhang Y, Chen X, Lee EJ, Barber CJ, Chakrabarty R, Desgagné-Penix I, Haslam TM, Kim YB, Liu E, MacNevin G, Masada-Atsumi S, Reed DW, Stout JM, Zerbe P, ... ... Ro DK, et al. Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest. Journal of Biotechnology. 166: 122-34. PMID 23602801 DOI: 10.1016/J.Jbiotec.2013.04.004  0.381
2012 Nguyen TD, MacNevin G, Ro DK. De novo synthesis of high-value plant sesquiterpenoids in yeast. Methods in Enzymology. 517: 261-78. PMID 23084943 DOI: 10.1016/B978-0-12-404634-4.00013-9  0.464
2012 Pickel B, Drew DP, Manczak T, Weitzel C, Simonsen HT, Ro DK. Identification and characterization of a kunzeaol synthase from Thapsia garganica: implications for the biosynthesis of the pharmaceutical thapsigargin. The Biochemical Journal. 448: 261-71. PMID 22938155 DOI: 10.1042/Bj20120654  0.397
2012 Attia M, Kim SU, Ro DK. Molecular cloning and characterization of (+)-epi-α-bisabolol synthase, catalyzing the first step in the biosynthesis of the natural sweetener, hernandulcin, in Lippia dulcis. Archives of Biochemistry and Biophysics. 527: 37-44. PMID 22867794 DOI: 10.1016/J.Abb.2012.07.010  0.344
2012 Pyle BW, Tran HT, Pickel B, Haslam TM, Gao Z, MacNevin G, Vederas JC, Kim SU, Ro DK. Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis). The Febs Journal. 279: 3136-46. PMID 22776156 DOI: 10.1111/J.1742-4658.2012.08692.X  0.451
2012 Rowe HC, Ro DK, Rieseberg LH. Response of sunflower (Helianthus annuus L.) leaf surface defenses to exogenous methyl jasmonate. Plos One. 7: e37191. PMID 22623991 DOI: 10.1371/Journal.Pone.0037191  0.343
2012 Facchini PJ, Bohlmann J, Covello PS, De Luca V, Mahadevan R, Page JE, Ro DK, Sensen CW, Storms R, Martin VJ. Synthetic biosystems for the production of high-value plant metabolites. Trends in Biotechnology. 30: 127-31. PMID 22209518 DOI: 10.1016/J.Tibtech.2011.10.001  0.412
2011 Ikezawa N, Göpfert JC, Nguyen DT, Kim SU, O'Maille PE, Spring O, Ro DK. Lettuce costunolide synthase (CYP71BL2) and its homolog (CYP71BL1) from sunflower catalyze distinct regio- and stereoselective hydroxylations in sesquiterpene lactone metabolism. The Journal of Biological Chemistry. 286: 21601-11. PMID 21515683 DOI: 10.1074/Jbc.M110.216804  0.421
2011 Barriuso J, Nguyen DT, Li JW, Roberts JN, MacNevin G, Chaytor JL, Marcus SL, Vederas JC, Ro DK. Double oxidation of the cyclic nonaketide dihydromonacolin L to monacolin J by a single cytochrome P450 monooxygenase, LovA. Journal of the American Chemical Society. 133: 8078-81. PMID 21495633 DOI: 10.1021/Ja201138V  0.384
2011 Ro DK. Terpenoid Biosynthesis Plant Metabolism and Biotechnology. 217-240. DOI: 10.1002/9781119991311.ch8  0.302
2010 Nguyen DT, Göpfert JC, Ikezawa N, Macnevin G, Kathiresan M, Conrad J, Spring O, Ro DK. Biochemical conservation and evolution of germacrene A oxidase in asteraceae. The Journal of Biological Chemistry. 285: 16588-98. PMID 20351109 DOI: 10.1074/Jbc.M110.111757  0.432
2009 Göpfert JC, Macnevin G, Ro DK, Spring O. Identification, functional characterization and developmental regulation of sesquiterpene synthases from sunflower capitate glandular trichomes. Bmc Plant Biology. 9: 86. PMID 19580670 DOI: 10.1186/1471-2229-9-86  0.362
2008 Ro DK, Ouellet M, Paradise EM, Burd H, Eng D, Paddon CJ, Newman JD, Keasling JD. Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. Bmc Biotechnology. 8: 83. PMID 18983675 DOI: 10.1186/1472-6750-8-83  0.394
2007 Chang MC, Eachus RA, Trieu W, Ro DK, Keasling JD. Engineering Escherichia coli for production of functionalized terpenoids using plant P450s. Nature Chemical Biology. 3: 274-7. PMID 17438551 DOI: 10.1038/Nchembio875  0.415
2007 Shiba Y, Paradise EM, Kirby J, Ro DK, Keasling JD. Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae for high-level production of isoprenoids. Metabolic Engineering. 9: 160-8. PMID 17196416 DOI: 10.1016/J.Ymben.2006.10.005  0.355
2006 Ro DK, Paradise EM, Ouellet M, Fisher KJ, Newman KL, Ndungu JM, Ho KA, Eachus RA, Ham TS, Kirby J, Chang MC, Withers ST, Shiba Y, Sarpong R, Keasling JD. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature. 440: 940-3. PMID 16612385 DOI: 10.1038/Nature04640  0.342
2006 Ro DK, Bohlmann J. Diterpene resin acid biosynthesis in loblolly pine (Pinus taeda): functional characterization of abietadiene/levopimaradiene synthase (PtTPS-LAS) cDNA and subcellular targeting of PtTPS-LAS and abietadienol/abietadienal oxidase (PtAO, CYP720B1). Phytochemistry. 67: 1572-8. PMID 16497345 DOI: 10.1016/J.Phytochem.2006.01.011  0.446
2006 Ro DK, Ehlting J, Keeling CI, Lin R, Mattheus N, Bohlmann J. Microarray expression profiling and functional characterization of AtTPS genes: duplicated Arabidopsis thaliana sesquiterpene synthase genes At4g13280 and At4g13300 encode root-specific and wound-inducible (Z)-gamma-bisabolene synthases. Archives of Biochemistry and Biophysics. 448: 104-16. PMID 16297850 DOI: 10.1016/J.Abb.2005.09.019  0.405
2005 Ro DK, Arimura G, Lau SY, Piers E, Bohlmann J. Loblolly pine abietadienol/abietadienal oxidase PtAO (CYP720B1) is a multifunctional, multisubstrate cytochrome P450 monooxygenase. Proceedings of the National Academy of Sciences of the United States of America. 102: 8060-5. PMID 15911762 DOI: 10.1073/Pnas.0500825102  0.436
2004 Chen F, Ro DK, Petri J, Gershenzon J, Bohlmann J, Pichersky E, Tholl D. Characterization of a root-specific arabidopsis terpene synthase responsible for the formation of the volatile monoterpene 1,8-cineole Plant Physiology. 135: 1956-1966. PMID 15299125 DOI: 10.1104/Pp.104.044388  0.36
2004 Ro DK, Douglas CJ. Reconstitution of the entry point of plant phenylpropanoid metabolism in yeast (Saccharomyces cerevisiae): implications for control of metabolic flux into the phenylpropanoid pathway. The Journal of Biological Chemistry. 279: 2600-7. PMID 14607837 DOI: 10.1074/Jbc.M309951200  0.518
2002 Ro DK, Ehlting J, Douglas CJ. Cloning, functional expression, and subcellular localization of multiple NADPH-cytochrome P450 reductases from hybrid poplar. Plant Physiology. 130: 1837-51. PMID 12481067 DOI: 10.1104/Pp.008011  0.58
2001 Ro DK, Mah N, Ellis BE, Douglas CJ. Functional characterization and subcellular localization of poplar (Populus trichocarpa x Populus deltoides) cinnamate 4-hydroxylase. Plant Physiology. 126: 317-29. PMID 11351095 DOI: 10.1104/Pp.126.1.317  0.513
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