Pengyu Yang, Ph.D. - Publications

Affiliations: 
2011-2017 Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Chemistry, Chemical Biology, Translational Medicine

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Cheng P, Yang P, Zhang H, Wang H. Prediction Models for Return of Spontaneous Circulation in Patients with Cardiac Arrest: A Systematic Review and Critical Appraisal. Emergency Medicine International. 2023: 6780941. PMID 38035124 DOI: 10.1155/2023/6780941  0.59
2023 Ren X, Chang C, Qi T, Yang P, Wang Y, Zhou X, Guan F, Li X. Clusterin Is a Prognostic Biomarker of Lower-Grade Gliomas and Is Associated with Immune Cell Infiltration. International Journal of Molecular Sciences. 24. PMID 37686218 DOI: 10.3390/ijms241713413  0.611
2023 Sun K, Zhang Y, Li Y, Yang P, Sun Y. Biochemical Targets and Molecular Mechanism of Matrine against Aging. International Journal of Molecular Sciences. 24. PMID 37373246 DOI: 10.3390/ijms241210098  0.637
2023 Li H, Ren X, Pang X, Yang P, Lu Y, Guan F, Wang Y, Li X. LacNAc modification in bone marrow stromal cells enhances resistance of myelodysplastic syndrome cells to chemotherapeutic drugs. Biochimica Et Biophysica Acta. Molecular Cell Research. 119492. PMID 37207914 DOI: 10.1016/j.bbamcr.2023.119492  0.644
2023 Shu W, Wang Y, Li C, Zhang L, Zhuoma D, Yang P, Yan G, Chen C, Ba Y, Du P, Wang X. Single-cell Expression Atlas Reveals Cell Heterogeneity in the Creeping Fat of Crohn's Disease. Inflammatory Bowel Diseases. PMID 36715181 DOI: 10.1093/ibd/izac266  0.599
2022 Yu S, Wang J, Zeng L, Yang P, Tang P, Su S. The prevalence of social frailty among older adults: A systematic review and meta-analysis. Geriatric Nursing (New York, N.Y.). 49: 101-108. PMID 36470103 DOI: 10.1016/j.gerinurse.2022.11.009  0.575
2022 Cui Z, Yang P, Li X, Wang H. An alternative excitation method for electrical impedance tomography. The Review of Scientific Instruments. 93: 044710. PMID 35489953 DOI: 10.1063/5.0083681  0.592
2021 Zhang L, Yang P, Feng H, Zhao Q, Liu H. Using Network Distance Analysis to Predict lncRNA-miRNA Interactions. Interdisciplinary Sciences, Computational Life Sciences. PMID 34232474 DOI: 10.1007/s12539-021-00458-z  0.585
2021 Shalhout SZ, Yang PY, Grzelak EM, Nutsch K, Shao S, Zambaldo C, Iaconelli J, Ibrahim L, Stanton C, Chadwick SR, Chen E, DeRan M, Li S, Hull M, Wu X, et al. YAP-dependent proliferation by a small molecule targeting annexin A2. Nature Chemical Biology. PMID 33723431 DOI: 10.1038/s41589-021-00755-0  0.777
2021 Feng H, Zhang L, Li S, Liu L, Yang T, Yang P, Zhao J, Arkin IT, Liu H. Predicting the Reproductive Toxicity of Chemicals Using Ensemble Learning Methods and Molecular Fingerprints. Toxicology Letters. PMID 33421549 DOI: 10.1016/j.toxlet.2021.01.002  0.614
2020 Wu Y, Zhang L, Cao J, Wang H, Ye C, Zhuoma D, Yang P, Wang X. Efficacy of infliximab treatment on the mucosal healing of different intestinal segments in patients with ileocolonic Crohn's disease. Therapeutic Advances in Gastroenterology. 13: 1756284820976923. PMID 33425009 DOI: 10.1177/1756284820976923  0.586
2020 Wang H, Ye C, Wu Y, Yang P, Chen C, Liu Z, Wang X. Exosomes in Inflammatory Bowel Disease: What We Learnt So Far? Current Drug Targets. PMID 32342815 DOI: 10.2174/1389450121666200428102330  0.619
2020 Yang PY, Zou H, Amso Z, Lee C, Huang D, Woods AK, Nguyen-Tran VTB, Schultz PG, Shen W. New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice. Bioconjugate Chemistry. PMID 32243137 DOI: 10.1021/Acs.Bioconjchem.0C00093  0.766
2019 Yang P, Kang W, Pan Y, Zhao X, Duan L. Overexpression of HOXC6 promotes cell proliferation and migration via MAPK signaling and predicts a poor prognosis in glioblastoma. Cancer Management and Research. 11: 8167-8179. PMID 31564976 DOI: 10.2147/CMAR.S209904  0.61
2019 Zhang Y, Zheng A, Xu R, Zhou F, Hao A, Yang H, Yang P. NR2F1-induced NR2F1-AS1 promotes esophageal squamous cell carcinoma progression via activating Hedgehog signaling pathway. Biochemical and Biophysical Research Communications. PMID 31530388 DOI: 10.1016/j.bbrc.2019.09.015  0.631
2018 Sun K, Yang P, Zhao R, Bai Y, Guo Z. Matrine Attenuates D-Galactose-Induced Aging-Related Behavior in Mice Inhibition of Cellular Senescence and Oxidative Stress. Oxidative Medicine and Cellular Longevity. 2018: 7108604. PMID 30598725 DOI: 10.1155/2018/7108604  0.608
2018 Zhao Q, Xu H, Hong S, Song N, Xie J, Yan Z, Wang R, Yang P, Jiang X. Rapeseed protein-derived antioxidant peptide RAP ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. Molecular Pharmaceutics. PMID 30543441 DOI: 10.1021/Acs.Molpharmaceut.8B01030  0.654
2018 Muppidi A, Lee SJ, Hsu CH, Zou H, Lee C, Pflimlin E, Mahankali M, Yang P, Chao E, Ahmad I, Crameri A, Wang D, Woods A, Shen W. Design and Synthesis of Potent, Long-Acting Lipidated Relaxin-2 Analogs. Bioconjugate Chemistry. PMID 30543420 DOI: 10.1021/Acs.Bioconjchem.8B00764  0.775
2018 Sun K, Bai Y, Zhao R, Guo Z, Su X, Li P, Yang P. Neuroprotective effects of matrine on scopolamine-induced amnesia via inhibition of AChE/BuChE and oxidative stress. Metabolic Brain Disease. PMID 30406376 DOI: 10.1007/s11011-018-0335-y  0.603
2018 Liu N, Li N, Yang P, Sun C, Fang J, Wang S. The complete mitochondrial genome of Damora sagana and phylogenetic analyses of the family Nymphalidae. Genes & Genomics. 40: 109-122. PMID 29892904 DOI: 10.1007/s13258-017-0614-8  0.613
2018 Yang P, Zou H, Lee C, Muppidi A, Chao E, Fu Q, Luo X, Wang D, Schultz PG, Shen W. A Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate-Induced Mouse Colitis Models. Journal of Medicinal Chemistry. PMID 29528634 DOI: 10.1021/Acs.Jmedchem.7B00768  0.768
2017 Luo X, Fu G, Wang RE, Zhu X, Zambaldo C, Liu R, Liu T, Lyu X, Du J, Xuan W, Yao A, Reed SA, Kang M, Zhang Y, Guo H, ... Yang PY, et al. Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria. Nature Chemical Biology. PMID 28604693 DOI: 10.1038/Nchembio.2405  0.724
2016 Wang Y, Du J, Zou H, Liu Y, Zhang Y, Gonzalez J, Chao E, Lu L, Yang P, Parker H, Nguyen-Tran V, Shen W, Wang D, Schultz PG, Wang F. Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-Dependent Insulinotropic Polypeptide Receptors. Angewandte Chemie (International Ed. in English). PMID 27595986 DOI: 10.1002/Anie.201606321  0.768
2016 Cao Y, Rodgers DT, Du J, Ahmad I, Hampton EN, Ma JS, Mazagova M, Choi SH, Yun HY, Xiao H, Yang P, Luo X, Lim RK, Pugh HM, Wang F, et al. Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer. Angewandte Chemie (International Ed. in English). 55: 7520-4. PMID 27145250 DOI: 10.1002/Anie.201601902  0.743
2016 Yang PY, Zou H, Chao E, Sherwood L, Nunez V, Keeney M, Ghartey-Tagoe E, Ding Z, Quirino H, Luo X, Welzel G, Chen G, Singh P, Woods AK, Schultz PG, et al. Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery. Proceedings of the National Academy of Sciences of the United States of America. 113: 4140-5. PMID 27035989 DOI: 10.1073/Pnas.1601653113  0.773
2016 Luo X, Zambaldo C, Liu T, Zhang Y, Xuan W, Wang C, Reed SA, Yang PY, Wang RE, Javahishvili T, Schultz PG, Young TS. Recombinant thiopeptides containing noncanonical amino acids. Proceedings of the National Academy of Sciences of the United States of America. 113: 3615-20. PMID 26976568 DOI: 10.1073/Pnas.1602733113  0.767
2016 Muppidi A, Zou H, Yang PY, Chao E, Sherwood L, Nunez V, Woods AK, Schultz PG, Lin Q, Shen W. Design of Potent and Proteolytically Stable Oxyntomodulin Analogs. Acs Chemical Biology. 11: 324-8. PMID 26727558 DOI: 10.1021/Acschembio.5B00787  0.713
2015 Yang P, Liu K. Activity-based protein profiling: recent advances in probe development and applications. Chembiochem : a European Journal of Chemical Biology. 16: 712-24. PMID 25652106 DOI: 10.1002/Cbic.201402582  0.669
2014 Xiao H, Peters FB, Yang PY, Reed S, Chittuluru JR, Schultz PG. Genetic incorporation of histidine derivatives using an engineered pyrrolysyl-tRNA synthetase. Acs Chemical Biology. 9: 1092-6. PMID 24506189 DOI: 10.1021/Cb500032C  0.766
2013 Wang F, Sambandan D, Halder R, Wang J, Batt SM, Weinrick B, Ahmad I, Yang P, Zhang Y, Kim J, Hassani M, Huszar S, Trefzer C, Ma Z, Kaneko T, et al. Identification of a small molecule with activity against drug-resistant and persistent tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 110: E2510-7. PMID 23776209 DOI: 10.1073/Pnas.1309171110  0.767
2013 Nasheri N, Joyce M, Rouleau Y, Yang P, Yao S, Tyrrell DL, Pezacki JP. Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication. Chemistry & Biology. 20: 570-82. PMID 23601646 DOI: 10.1016/J.Chembiol.2013.03.014  0.647
2013 Chatterjee A, Xiao H, Yang PY, Soundararajan G, Schultz PG. A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli. Angewandte Chemie (International Ed. in English). 52: 5106-9. PMID 23554007 DOI: 10.1002/Anie.201301094  0.796
2013 Wang F, Sambandan D, Halder R, Wang J, Batt SM, Weinrick B, Ahmad I, Yang P, Zhang Y, Kim J, Hassani M, Huszar S, Trefzer C, Ma Z, Kaneko T, et al. Identification of a small molecule with activity against drug-resistant and persistent tuberculosis (vol 110, pg E2510, 2013) Proceedings of the National Academy of Sciences of the United States of America. 110: 15848-15848. DOI: 10.1073/Pnas.1315914110  0.761
2013 Wang F, Sambandan D, Halder R, Wang J, Batt SM, Weinrick B, Ahmad I, Yang P, Zhang Y, Kim J, Hassani M, Huszar S, Trefzer C, Ma Z, Kaneko T, et al. Erratum: Identification of a small molecule with activity against drug-resistant and persistent tuberculosis (Proceedings of the National Academy of Sciences of the United States of America (2013) 27:110 (E2510-E2517)) Proceedings of the National Academy of Sciences of the United States of America. 110. DOI: 10.1073/Pnas.1314629110  0.758
2012 Wang D, Wang J, Bonamy GM, Meeusen S, Brusch RG, Turk C, Yang P, Schultz PG. A small molecule promotes mitochondrial fusion in mammalian cells. Angewandte Chemie (International Ed. in English). 51: 9302-5. PMID 22907892 DOI: 10.1002/Anie.201204589  0.757
2012 Yang PY, Wang M, Liu K, Ngai MH, Sheriff O, Lear MJ, Sze SK, He CY, Yao SQ. Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 8403-13. PMID 22674877 DOI: 10.1002/Chem.201200482  0.757
2012 Yang PY, Wang M, Li L, Wu H, He CY, Yao SQ. Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 6528-41. PMID 22488888 DOI: 10.1002/Chem.201103322  0.787
2012 Yang PY, Wang M, He CY, Yao SQ. Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei. Chemical Communications (Cambridge, England). 48: 835-7. PMID 22124229 DOI: 10.1039/C1Cc16178D  0.743
2011 Yang PY, Liu K, Zhang C, Chen GY, Shen Y, Ngai MH, Lear MJ, Yao SQ. Chemical modification and organelle-specific localization of orlistat-like natural-product-based probes. Chemistry, An Asian Journal. 6: 2762-75. PMID 21744505 DOI: 10.1002/Asia.201100306  0.802
2011 Hu M, Li L, Wu H, Su Y, Yang PY, Uttamchandani M, Xu QH, Yao SQ. Multicolor, one- and two-photon imaging of enzymatic activities in live cells with fluorescently Quenched Activity-Based Probes (qABPs). Journal of the American Chemical Society. 133: 12009-20. PMID 21732629 DOI: 10.1021/Ja200808Y  0.776
2011 Liu K, Yang PY, Na Z, Yao SQ. Dynamic monitoring of newly synthesized proteomes: up-regulation of myristoylated protein kinase A during butyric acid induced apoptosis. Angewandte Chemie (International Ed. in English). 50: 6776-81. PMID 21678537 DOI: 10.1002/Anie.201102542  0.762
2011 Wu H, Ge J, Yang PY, Wang J, Uttamchandani M, Yao SQ. A peptide aldehyde microarray for high-throughput profiling of cellular events. Journal of the American Chemical Society. 133: 1946-54. PMID 21247160 DOI: 10.1021/Ja109597V  0.79
2010 Ngai MH, Yang PY, Liu K, Shen Y, Wenk MR, Yao SQ, Lear MJ. Click-based synthesis and proteomic profiling of lipstatin analogues. Chemical Communications (Cambridge, England). 46: 8335-7. PMID 20577697 DOI: 10.1039/C0Cc01276A  0.758
2010 Yang PY, Liu K, Ngai MH, Lear MJ, Wenk MR, Yao SQ. Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities. Journal of the American Chemical Society. 132: 656-66. PMID 20028024 DOI: 10.1021/Ja907716F  0.772
2009 Tan LP, Wu H, Yang PY, Kalesh KA, Zhang X, Hu M, Srinivasan R, Yao SQ. High-throughput discovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitors using click chemistry. Organic Letters. 11: 5102-5. PMID 19852491 DOI: 10.1021/Ol9023419  0.774
2009 Srinivasan R, Tan LP, Wu H, Yang PY, Kalesh KA, Yao SQ. High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening. Organic & Biomolecular Chemistry. 7: 1821-8. PMID 19590777 DOI: 10.1039/B902338K  0.783
2008 Yang PY, Wu H, Lee MY, Xu A, Srinivasan R, Yao SQ. Solid-phase synthesis of azidomethylene inhibitors targeting cysteine proteases. Organic Letters. 10: 1881-4. PMID 18407644 DOI: 10.1021/Ol800575Z  0.778
2008 Ng SL, Yang PY, Chen KY, Srinivasan R, Yao SQ. "Click" synthesis of small-molecule inhibitors targeting caspases. Organic & Biomolecular Chemistry. 6: 844-7. PMID 18292873 DOI: 10.1039/B718304F  0.776
2008 Shi JC, Yang P, Tong Q, Jia L. Palladium-catalyzed aminations of aryl halides with phosphine-functionalized imidazolium ligands. Dalton Transactions (Cambridge, England : 2003). 938-45. PMID 18259628 DOI: 10.1039/B714892E  0.641
2007 Kalesh K, Yang P, Srinivasan R, Yao S. Click Chemistry as a High-Throughput Amenable Platform in Catalomics Qsar & Combinatorial Science. 26: 1135-1144. DOI: 10.1002/Qsar.200740064  0.783
2006 Shi JC, Yang PY, Tong Q, Wu Y, Peng Y. Highly efficient and stable palladium/imidazolium salt-phosphine catalysts for Suzuki–Miyaura cross-coupling of aryl bromides Journal of Molecular Catalysis a: Chemical. 259: 7. DOI: 10.1016/J.Molcata.2006.04.025  0.627
2006 Yu HW, Shi JC, Zahng H, Yang PY, Wang XP, Jin ZL. Unsymmetric-1, 3-disubstituted imidazolium salt for palladium-catalyzed Suzuki–Miyaura cross-coupling reactions of aryl bromides Journal of Molecular Catalysis a: Chemical. 250: 15. DOI: 10.1016/J.Molcata.2006.01.034  0.629
2005 Yang G, Han X, Zhang W, Liu X, Yang P, Zhou Y, Bao X. Study on conformation interconversion of 3-alkyl-4-acetyl-3,4-dihydro-2H-1,4-benzoxazines from dynamic NMR experiments and ab initio density functional calculations. The Journal of Physical Chemistry. B. 109: 18690-8. PMID 16853404 DOI: 10.1021/Jp050874D  0.635
2005 Zhou YG, Yang PY, Han XW. Synthesis and highly enantioselective hydrogenation of exocyclic enamides: (Z)-3-arylidene-4-acetyl-3,4-dihydro-2H- 1,4-benzoxazines. The Journal of Organic Chemistry. 70: 1679-83. PMID 15730287 DOI: 10.1021/Jo048212S  0.626
2004 Yang PY, Zhou YG. The enantioselective total synthesis of alkaloid (−)-galipeine Tetrahedron: Asymmetry. 15: 1145. DOI: 10.1016/J.Tetasy.2004.02.012  0.634
2003 Wang WB, Lu SM, Yang PY, Han XW, Zhou YG. Highly enantioselective iridium-catalyzed hydrogenation of heteroaromatic compounds, quinolines. Journal of the American Chemical Society. 125: 10536-7. PMID 12940733 DOI: 10.1021/Ja0353762  0.648
2002 Gildersleeve J, Janes J, Ulrich H, Yang P, Barbas C, Schultz PG. Development of a genetic selection for catalytic antibodies. Bioorganic & Medicinal Chemistry Letters. 12: 1691-4. PMID 12039592 DOI: 10.1016/S0960-894X(02)00198-1  0.77
2001 Yin J, Mundorff EC, Yang PL, Wendt KU, Hanway D, Stevens RC, Schultz PG. A comparative analysis of the immunological evolution of antibody 28B4. Biochemistry. 40: 10764-73. PMID 11535051 DOI: 10.1021/Bi010536C  0.635
1999 Yang PL, Schultz PG. Mutational analysis of the affinity maturation of antibody 48G7. Journal of Molecular Biology. 294: 1191-201. PMID 10600377 DOI: 10.1006/Jmbi.1999.3197  0.637
1996 Patten PA, Gray NS, Yang PL, Marks CB, Wedemayer GJ, Boniface JJ, Stevens RC, Schultz PG. The immunological evolution of catalysis. Science (New York, N.Y.). 271: 1086-91. PMID 8599084 DOI: 10.1126/Science.271.5252.1086  0.773
1995 Ulrich HD, Patten PA, Yang PL, Romesberg FE, Schultz PG. Expression studies of catalytic antibodies. Proceedings of the National Academy of Sciences of the United States of America. 92: 11907-11. PMID 8524873 DOI: 10.1073/Pnas.92.25.11907  0.77
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