| Year |
Citation |
Score |
| 2023 |
Bondarenko V, Chen Q, Singewald K, Haloi N, Tillman TS, Howard RJ, Lindahl E, Xu Y, Tang P. Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization. Acs Chemical Neuroscience. PMID 36821490 DOI: 10.1021/acschemneuro.2c00783 |
0.721 |
|
| 2023 |
Tillman TS, Chen Q, Bondarenko V, Coleman JA, Xu Y, Tang P. SARS-CoV-2 Spike Protein Downregulates Cell Surface α7nAChR through a Helical Motif in the Spike Neck. Acs Chemical Neuroscience. PMID 36745901 DOI: 10.1021/acschemneuro.2c00610 |
0.619 |
|
| 2022 |
Bondarenko V, Wells MM, Chen Q, Tillman TS, Singewald K, Lawless MJ, Caporoso J, Brandon N, Coleman JA, Saxena S, Lindahl E, Xu Y, Tang P. Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor. Nature Communications. 13: 793. PMID 35145092 DOI: 10.1038/s41467-022-28400-x |
0.689 |
|
| 2021 |
Xiao J, Bondarenko V, Wang Y, Suma A, Wells M, Chen Q, Tillman T, Luo Y, Yu B, Dailey WP, Eckenhoff R, Tang P, Carnevale V, Klein ML, Xu Y. Regulation and drug modulation of a voltage-gated sodium channel: Pivotal role of the S4-S5 linker in activation and slow inactivation. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34260401 DOI: 10.1073/pnas.2102285118 |
0.69 |
|
| 2020 |
Yao L, Wells M, Wu X, Xu Y, Zhang L, Xiong W. Membrane cholesterol dependence of cannabinoid modulation of glycine receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32608538 DOI: 10.1096/Fj.201903093R |
0.34 |
|
| 2020 |
Caporoso J, Moses M, Koper K, Tillman TS, Jiang L, Brandon N, Chen Q, Tang P, Xu Y. A Thermal Place Preference Test for Discovery of Neuropathic Pain Drugs. Acs Chemical Neuroscience. PMID 32191433 DOI: 10.1021/Acschemneuro.0C00013 |
0.602 |
|
| 2020 |
Tillman TS, Choi Z, Xu Y, Tang P. Functional Tolerance to Cysteine Mutations in Human α7 Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience. PMID 31951367 DOI: 10.1021/Acschemneuro.9B00647 |
0.694 |
|
| 2019 |
Bondarenko V, Wells MM, Chen Q, Singewald KC, Saxena S, Xu Y, Tang P. F Paramagnetic Relaxation-Based NMR for Quaternary Structural Restraints of Ion Channels. Acs Chemical Biology. PMID 31525026 DOI: 10.1021/Acschembio.9B00692 |
0.683 |
|
| 2019 |
Wells MM, Bondarenko V, Tillman TS, Singewald K, Lawless MJ, Caporoso J, Brandon N, Chen C, Kinde MN, Saxena S, Xu Y, Lindahl E, Tang P. Integrative Structure Determination of α7nAChR Intracellular Domain Biophysical Journal. 116: 394a. DOI: 10.1016/J.Bpj.2018.11.2133 |
0.771 |
|
| 2019 |
Tillman TS, Xu Y, Tang P. Functional Tolerance of Human α7 Nicotinic Acetylcholine Receptor to Cysteine Labeling Biophysical Journal. 116: 393a. DOI: 10.1016/J.Bpj.2018.11.2128 |
0.646 |
|
| 2019 |
Bondarenko V, Wells M, Chen Q, Tillman T, Xu Y, Tang P. Long Distance NMR Restraints for the Flexible α7nAChR Intracellular Domain Biophysical Journal. 116: 393a. DOI: 10.1016/J.Bpj.2018.11.2127 |
0.651 |
|
| 2018 |
Chen Q, Wells MM, Arjunan P, Tillman TS, Cohen AE, Xu Y, Tang P. Structural basis of neurosteroid anesthetic action on GABA receptors. Nature Communications. 9: 3972. PMID 30266951 DOI: 10.1038/S41467-018-06361-4 |
0.742 |
|
| 2018 |
Wang Y, Yang E, Wells MM, Bondarenko V, Woll K, Carnevale V, Granata D, Klein ML, Eckenhoff RG, Dailey WP, Covarrubias M, Tang P, Xu Y. Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. The Journal of General Physiology. PMID 30018039 DOI: 10.1085/Jgp.201811993 |
0.736 |
|
| 2018 |
Zhang C, Brandon NR, Koper K, Tang P, Xu Y, Dou H. Invasion of Peripheral Immune Cells into Brain Parenchyma after Cardiac Arrest and Resuscitation. Aging and Disease. 9: 412-425. PMID 29896429 DOI: 10.14336/Ad.2017.0926 |
0.611 |
|
| 2018 |
Bondarenko V, Wells M, Xu Y, Tang P. Solution NMR Studies of Anesthetic Interactions with Ion Channels. Methods in Enzymology. 603: 49-66. PMID 29673534 DOI: 10.1016/Bs.Mie.2018.01.018 |
0.72 |
|
| 2018 |
Chen Q, Xu Y, Tang P. X-Ray Crystallographic Studies for Revealing Binding Sites of General Anesthetics in Pentameric Ligand-Gated Ion Channels. Methods in Enzymology. 603: 21-47. PMID 29673527 DOI: 10.1016/Bs.Mie.2018.01.017 |
0.708 |
|
| 2018 |
Chen Q, Wells MM, Arjunan P, Tillman TS, Adell D, Cohen AE, Xu Y, Tang P. Structures and Functions of ELIC-GABAAR Chimeras Biophysical Journal. 114: 299a. DOI: 10.1016/J.Bpj.2017.11.1705 |
0.645 |
|
| 2017 |
Ion BF, Wells MM, Chen Q, Xu Y, Tang P. Ketamine Inhibition of the Pentameric Ligand-Gated Ion Channel GLIC. Biophysical Journal. 113: 605-612. PMID 28793215 DOI: 10.1016/J.Bpj.2017.06.041 |
0.731 |
|
| 2017 |
Wells MM, Reinert N, Tang P, Xu Y. Structure-Based Discovery of Novel Glycinergic Modulators Biophysical Journal. 112: 556a. DOI: 10.1016/J.Bpj.2016.11.2998 |
0.724 |
|
| 2017 |
Ion BF, Wells MM, Xu Y, Tang P. Ketamine Inhibition of Pentameric Ligand-Gated Ion Channels - Insights from Molecular Dynamics Simulations Biophysical Journal. 112: 554a. DOI: 10.1016/J.Bpj.2016.11.2989 |
0.706 |
|
| 2017 |
Wang Y, Wells MM, Dailey W, Eckenhoff R, Tang P, Xu Y. Multiple Mechanisms of Propofol Inhibition of the Voltage-Gated Sodium Channel Nachbac: A 19 F NMR Investigation Biophysical Journal. 112: 18a. DOI: 10.1016/J.Bpj.2016.11.133 |
0.731 |
|
| 2016 |
Chen Q, Wells MM, Tillman TS, Kinde MN, Cohen A, Xu Y, Tang P. Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC. Structure (London, England : 1993). PMID 27916519 DOI: 10.1016/J.Str.2016.11.007 |
0.804 |
|
| 2016 |
Kinde MN, Bondarenko V, Granata D, Bu W, Grasty KC, Loll PJ, Carnevale V, Klein ML, Eckenhoff RG, Tang P, Xu Y. Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac. Proceedings of the National Academy of Sciences of the United States of America. PMID 27856739 DOI: 10.1073/Pnas.1609939113 |
0.8 |
|
| 2016 |
Jia LJ, Tang P, Brandon NR, Luo Y, Yu B, Xu Y. Effects of Propofol General Anesthesia on Olfactory Relearning. Scientific Reports. 6: 33538. PMID 27628686 DOI: 10.1038/Srep33538 |
0.62 |
|
| 2016 |
Tillman TS, Alvarez FJ, Reinert NJ, Liu C, Wang D, Xu Y, Xiao K, Zhang P, Tang P. Functional Human α7 Nicotinic Acetylcholine Receptor (nAChR) Generated from E. coli. The Journal of Biological Chemistry. PMID 27385587 DOI: 10.1074/Jbc.M116.729970 |
0.685 |
|
| 2016 |
Stollings LM, Jia LJ, Tang P, Dou H, Lu B, Xu Y. Immune Modulation by Volatile Anesthetics. Anesthesiology. PMID 27286478 DOI: 10.1097/Aln.0000000000001195 |
0.611 |
|
| 2016 |
Kinde MN, Bu W, Chen Q, Xu Y, Eckenhoff RG, Tang P. Common Anesthetic-binding Site for Inhibition of Pentameric Ligand-gated Ion Channels. Anesthesiology. PMID 26756520 DOI: 10.1097/Aln.0000000000001005 |
0.813 |
|
| 2016 |
Wells MM, Maxwell A, Xu Y, Tang P. Novel Modulators of Glycine Receptors Biophysical Journal. 110: 543a. DOI: 10.1016/J.Bpj.2015.11.2905 |
0.705 |
|
| 2015 |
Zhou DW, Mowrey DD, Tang P, Xu Y. Percolation Model of Sensory Transmission and Loss of Consciousness Under General Anesthesia. Physical Review Letters. 115: 108103. PMID 26382705 DOI: 10.1103/Physrevlett.115.108103 |
0.732 |
|
| 2015 |
Chen Q, Kinde MN, Arjunan P, Wells MM, Cohen AE, Xu Y, Tang P. Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC. Scientific Reports. 5: 13833. PMID 26346220 DOI: 10.1038/Srep13833 |
0.821 |
|
| 2015 |
Kinde MN, Chen Q, Lawless MJ, Mowrey DD, Xu J, Saxena S, Xu Y, Tang P. Conformational Changes Underlying Desensitization of the Pentameric Ligand-Gated Ion Channel ELIC. Structure (London, England : 1993). 23: 995-1004. PMID 25960405 DOI: 10.1016/J.Str.2015.03.017 |
0.806 |
|
| 2015 |
Chong Y, Kleinhammes A, Tang P, Xu Y, Wu Y. Dominant Alcohol-Protein Interaction via Hydration-Enabled Enthalpy-Driven Binding Mechanism. The Journal of Physical Chemistry. B. 119: 5367-75. PMID 25856773 DOI: 10.1021/Acs.Jpcb.5B00378 |
0.673 |
|
| 2015 |
Wells MM, Tillman TS, Mowrey DD, Sun T, Xu Y, Tang P. Ensemble-based virtual screening for cannabinoid-like potentiators of the human glycine receptor α1 for the treatment of pain. Journal of Medicinal Chemistry. 58: 2958-66. PMID 25790278 DOI: 10.1021/Jm501873P |
0.685 |
|
| 2015 |
Mowrey DD, Kinde MN, Xu Y, Tang P. Atomistic insights into human Cys-loop receptors by solution NMR. Biochimica Et Biophysica Acta. 1848: 307-14. PMID 24680782 DOI: 10.1016/J.Bbamem.2014.03.014 |
0.816 |
|
| 2015 |
Chen Q, Kinde MN, Cohen AE, Tang P, Xu Y. Crystal View of Anesthetics and Alcohols Bound in the Pore of ELIC Biophysical Journal. 108: 55a. DOI: 10.1016/J.Bpj.2014.11.333 |
0.802 |
|
| 2015 |
Kinde MN, Bu W, Seyoum E, Chen Q, Wells MM, Mowrey DD, Eckenhoff RG, Xu Y, Tang P. A Shared Binding Site for Propofol and Thiopental in ELIC Biophysical Journal. 108: 55a. DOI: 10.1016/J.Bpj.2014.11.332 |
0.798 |
|
| 2015 |
Wells MM, Mowrey DD, Seyoum E, Sun T, Xu Y, Tang P. Positive Modulators of Glycine Receptors with Analgesic Potential Identified by Virtual Screening Biophysical Journal. 108: 357a. DOI: 10.1016/J.Bpj.2014.11.1955 |
0.682 |
|
| 2014 |
Tillman TS, Seyoum E, Mowrey DD, Xu Y, Tang P. ELIC-α7 Nicotinic acetylcholine receptor (α7nAChR) chimeras reveal a prominent role of the extracellular-transmembrane domain interface in allosteric modulation. The Journal of Biological Chemistry. 289: 13851-7. PMID 24695730 DOI: 10.1074/Jbc.M113.524611 |
0.704 |
|
| 2014 |
Samuelsson AR, Brandon NR, Tang P, Xu Y. Cellular registration without behavioral recall of olfactory sensory input under general anesthesia. Anesthesiology. 120: 890-905. PMID 24694846 DOI: 10.1097/Aln.0000000000000137 |
0.616 |
|
| 2014 |
Bondarenko V, Mowrey DD, Tillman TS, Seyoum E, Xu Y, Tang P. NMR structures of the human α7 nAChR transmembrane domain and associated anesthetic binding sites. Biochimica Et Biophysica Acta. 1838: 1389-95. PMID 24384062 DOI: 10.1016/J.Bbamem.2013.12.018 |
0.728 |
|
| 2014 |
Chiara DC, Gill JF, Chen Q, Tillman T, Dailey WP, Eckenhoff RG, Xu Y, Tang P, Cohen JB. Photoaffinity labeling the propofol binding site in GLIC. Biochemistry. 53: 135-42. PMID 24341978 DOI: 10.1021/Bi401492K |
0.726 |
|
| 2014 |
Seyoum E, Tillman TS, Xu Y, Tang P. Functional Chimeras of the Human α7 Acetylcholine Receptor Provide Insights into Allosteric Modulation Biophysical Journal. 106: 342a. DOI: 10.1016/J.Bpj.2013.11.1953 |
0.708 |
|
| 2014 |
Mowrey DD, Liu Q, Bondarenko V, Chen Q, Seyoum E, Xu Y, Wu J, Tang P. Insights into the Distinctly Different Sensitivities of α7 and α7β2 nAChRs to the Volatile Anesthetic Isoflurane Biophysical Journal. 106: 341a. DOI: 10.1016/J.Bpj.2013.11.1952 |
0.698 |
|
| 2013 |
Mowrey DD, Liu Q, Bondarenko V, Chen Q, Seyoum E, Xu Y, Wu J, Tang P. Insights into distinct modulation of α7 and α7β2 nicotinic acetylcholine receptors by the volatile anesthetic isoflurane. The Journal of Biological Chemistry. 288: 35793-800. PMID 24194515 DOI: 10.1074/Jbc.M113.508333 |
0.715 |
|
| 2013 |
Wang HJ, Kleinhammes A, Tang P, Xu Y, Wu Y. Critical role of water in the binding of volatile anesthetics to proteins. The Journal of Physical Chemistry. B. 117: 12007-12. PMID 24050264 DOI: 10.1021/Jp407115J |
0.669 |
|
| 2013 |
Mowrey DD, Cui T, Jia Y, Ma D, Makhov AM, Zhang P, Tang P, Xu Y. Open-channel structures of the human glycine receptor α1 full-length transmembrane domain. Structure (London, England : 1993). 21: 1897-904. PMID 23994010 DOI: 10.1016/J.Str.2013.07.014 |
0.739 |
|
| 2013 |
Mowrey D, Chen Q, Liang Y, Liang J, Xu Y, Tang P. Signal transduction pathways in the pentameric ligand-gated ion channels. Plos One. 8: e64326. PMID 23667707 DOI: 10.1371/Journal.Pone.0064326 |
0.729 |
|
| 2013 |
Mowrey D, Cheng MH, Liu LT, Willenbring D, Lu X, Wymore T, Xu Y, Tang P. Asymmetric ligand binding facilitates conformational transitions in pentameric ligand-gated ion channels. Journal of the American Chemical Society. 135: 2172-80. PMID 23339564 DOI: 10.1021/Ja307275V |
0.74 |
|
| 2013 |
Bondarenko V, Mowrey D, Liu LT, Xu Y, Tang P. NMR resolved multiple anesthetic binding sites in the TM domains of the α4β2 nAChR. Biochimica Et Biophysica Acta. 1828: 398-404. PMID 23000369 DOI: 10.1016/J.Bbamem.2012.09.014 |
0.742 |
|
| 2013 |
Tillman T, Cheng MH, Chen Q, Tang P, Xu Y. Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics. The Biochemical Journal. 449: 61-8. PMID 22978431 DOI: 10.1042/Bj20121072 |
0.734 |
|
| 2013 |
Mowrey DD, Liu Q, Bondarenko, Chen Q, Seyoum E, Xu Y, Wu J, Tang P. Insights into distinct modulation of alpha 7 and alpha 7 beta 2 nicotinic acetylcholine receptors by the volatile anesthetic isoflurane. Journal of Biological Chemistry. 288: 35793-35800. DOI: 10.2210/Pdb2Maw/Pdb |
0.637 |
|
| 2013 |
Mowrey DD, Chen Q, Xu Y, Tang P. Mechanisms of Channel Activation in GLIC Biophysical Journal. 104: 67a. DOI: 10.1016/J.Bpj.2012.11.405 |
0.692 |
|
| 2013 |
Chen Q, Tillman TS, Xu Y, Tang P. Functional Modulation of the ELIC by General Anesthetics and Alcohols Biophysical Journal. 104: 635a. DOI: 10.1016/J.Bpj.2012.11.3511 |
0.663 |
|
| 2013 |
Bondarenko V, Mowrey D, Xu Y, Tang P. Anesthetic Binding Sites within the Transmembrane Domain of the α7 Nicotinic Acetylcholine Receptor Biophysical Journal. 104: 635a. DOI: 10.1016/J.Bpj.2012.11.3509 |
0.715 |
|
| 2013 |
Mowrey DD, Cheng MH, Liu LT, Willenbring D, Lu X, Wymore T, Xu Y, Tang P. Does Symmetry of Ligand Occupancy Matter to Conformational Transitions of Pentameric Ligand Gated Ion Channels? Biophysical Journal. 104: 380a. DOI: 10.1016/J.Bpj.2012.11.2116 |
0.726 |
|
| 2013 |
Kinde MN, Bondarenko V, Chen Q, Tillman TS, Xu Y, Tang P. ELIC Channel Conformational Changes Detected by 19F NMR Biophysical Journal. 104: 208a. DOI: 10.1016/J.Bpj.2012.11.1176 |
0.808 |
|
| 2013 |
Bondarenko V, Mowrey D, Xu Y, Tang P. Structures of α7 and α4β2 nAChR transmenbrane domains and associated binding sites for allosteric modulators Biochemical Pharmacology. 86: 1227. DOI: 10.1016/J.Bcp.2013.08.036 |
0.701 |
|
| 2013 |
Tillman TS, Seyoum E, Xu Y, Tang P. Functional chimera of the human α7 acetylcholine receptor for mechanistic investigations of allosteric modulation Biochemical Pharmacology. 86: 1226-1227. DOI: 10.1016/J.Bcp.2013.08.035 |
0.652 |
|
| 2012 |
Pan J, Chen Q, Willenbring D, Mowrey D, Kong XP, Cohen A, Divito CB, Xu Y, Tang P. Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine. Structure (London, England : 1993). 20: 1463-9. PMID 22958642 DOI: 10.1016/J.Str.2012.08.009 |
0.749 |
|
| 2012 |
Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, ... ... Xu Y, et al. In support of the BMRB. Nature Structural & Molecular Biology. 19: 854-60. PMID 22955930 DOI: 10.1038/Nsmb.2371 |
0.563 |
|
| 2012 |
Pan J, Chen Q, Willenbring D, Yoshida K, Tillman T, Kashlan OB, Cohen A, Kong XP, Xu Y, Tang P. Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine. Nature Communications. 3: 714. PMID 22395605 DOI: 10.1038/Ncomms1703 |
0.745 |
|
| 2012 |
Bondarenko V, Mowrey D, Tillman T, Cui T, Liu LT, Xu Y, Tang P. NMR structures of the transmembrane domains of the α4β2 nAChR. Biochimica Et Biophysica Acta. 1818: 1261-8. PMID 22361591 DOI: 10.1016/J.Bbamem.2012.02.008 |
0.714 |
|
| 2012 |
Cui T, Mowrey D, Bondarenko V, Tillman T, Ma D, Landrum E, Perez-Aguilar JM, He J, Wang W, Saven JG, Eckenhoff RG, Tang P, Xu Y. NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptor. Biochimica Et Biophysica Acta. 1818: 617-26. PMID 22155685 DOI: 10.1016/J.Bbamem.2011.11.021 |
0.73 |
|
| 2012 |
Xu Y, Mowrey D, Cui T, Perez-Aguilar J, Saven J, Eckenhoff R, Tang P. WSA major conformation Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Lkg/Pdb |
0.647 |
|
| 2012 |
Xu Y, Mowrey D, Cui T, Perez-Aguilar J, Saven J, Eckenhoff R, Tang P. WSA minor conformation Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr17992 |
0.646 |
|
| 2012 |
Tang P, Pan J, Chen Q, Yoshida K, Willenbring D, Tillman T, Kashlan O, Cohen A, Kong X, Xu Y. Structure and Function of ELIC Bound with the Antagonist Acetylcholine Biophysical Journal. 102: 112a-113a. DOI: 10.1016/J.Bpj.2011.11.634 |
0.74 |
|
| 2011 |
Willenbring D, Liu LT, Mowrey D, Xu Y, Tang P. Isoflurane alters the structure and dynamics of GLIC. Biophysical Journal. 101: 1905-12. PMID 22004744 DOI: 10.1016/J.Bpj.2011.09.026 |
0.754 |
|
| 2011 |
Wang HJ, Kleinhammes A, Tang P, Xu Y, Wu Y. Temperature dependence of lysozyme hydration and the role of elastic energy. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 83: 031924. PMID 21517540 DOI: 10.1103/Physreve.83.031924 |
0.614 |
|
| 2011 |
Xiong W, Cheng K, Cui T, Godlewski G, Rice KC, Xu Y, Zhang L. Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia. Nature Chemical Biology. 7: 296-303. PMID 21460829 DOI: 10.1038/Nchembio.552 |
0.311 |
|
| 2011 |
Liu LT, Li M, Mowrey D, Lu H, Liang J, Xu Y, Tang P. Anesthetic Modulation of Signal Transduction Pathways in the α4β2 nAchR Revealed by the Perturbation-Based Markovian Transmission Model Biophysical Journal. 100: 548a. DOI: 10.1016/J.Bpj.2010.12.3193 |
0.733 |
|
| 2011 |
Bondarenko V, Tillman T, Liu LT, Xu Y, Tang P. NMR Study of General Anesthetic Interactions with the Neuronal N-Acetylcholine Receptor Transmembrane Domain Biophysical Journal. 100: 275a. DOI: 10.1016/J.Bpj.2010.12.1711 |
0.738 |
|
| 2011 |
Willenbring D, Tian Liu L, Xu Y, Tang P. Binding of Isoflurane to Glic Alters the Structure and Dynamics of the Protein Biophysical Journal. 100: 273a. DOI: 10.1016/J.Bpj.2010.12.1701 |
0.75 |
|
| 2010 |
Chen Q, Cheng MH, Xu Y, Tang P. Anesthetic binding in a pentameric ligand-gated ion channel: GLIC. Biophysical Journal. 99: 1801-9. PMID 20858424 DOI: 10.1016/J.Bpj.2010.07.023 |
0.745 |
|
| 2010 |
Willenbring D, Xu Y, Tang P. The role of structured water in mediating general anesthetic action on alpha4beta2 nAChR. Physical Chemistry Chemical Physics : Pccp. 12: 10263-9. PMID 20661501 DOI: 10.1039/C003573D |
0.677 |
|
| 2010 |
Liu LT, Xu Y, Tang P. Mechanistic insights into xenon inhibition of NMDA receptors from MD simulations. The Journal of Physical Chemistry. B. 114: 9010-6. PMID 20560662 DOI: 10.1021/Jp101687J |
0.71 |
|
| 2010 |
Mowrey D, Haddadian EJ, Liu LT, Willenbring D, Xu Y, Tang P. Unresponsive correlated motion in alpha7 nAChR to halothane binding explains its functional insensitivity to volatile anesthetics. The Journal of Physical Chemistry. B. 114: 7649-55. PMID 20465243 DOI: 10.1021/Jp1009675 |
0.697 |
|
| 2010 |
Bondarenko V, Tillman T, Xu Y, Tang P. NMR structure of the transmembrane domain of the n-acetylcholine receptor beta2 subunit. Biochimica Et Biophysica Acta. 1798: 1608-14. PMID 20441771 DOI: 10.1016/J.Bbamem.2010.04.014 |
0.713 |
|
| 2010 |
Liu LT, Haddadian EJ, Willenbring D, Xu Y, Tang P. Higher susceptibility to halothane modulation in open- than in closed-channel alpha4beta2 nAChR revealed by molecular dynamics simulations. The Journal of Physical Chemistry. B. 114: 626-32. PMID 20014754 DOI: 10.1021/Jp908944E |
0.743 |
|
| 2010 |
Cui T, Canlas CG, Xu Y, Tang P. Anesthetic effects on the structure and dynamics of the second transmembrane domains of nAChR alpha4beta2. Biochimica Et Biophysica Acta. 1798: 161-6. PMID 19715664 DOI: 10.1016/J.Bbamem.2009.08.009 |
0.674 |
|
| 2010 |
Cui T, Tang P, Xu∗ Y. NMR of Transmembrane and Intracellular Domains of Human Nicotine Acetylcholine Receptor A7 Subunit Biophysical Journal. 98: 134a. DOI: 10.1016/J.Bpj.2009.12.723 |
0.685 |
|
| 2010 |
Bondarenko V, Tillman T, Xu Y, Tang P. Anesthetic Binding Sites in the Neuronal N-Acetylcholine Receptor Transmembrane Domain Biophysical Journal. 98: 133a. DOI: 10.1016/J.Bpj.2009.12.718 |
0.709 |
|
| 2010 |
Cheng MH, Xu Y, Coalson RD, Tang∗ P. Molecular Dynamics Investigation of Anesthetic Halothane Interactions with the Proton-Gated Ion Channel GLIC Biophysical Journal. 98: 703a. DOI: 10.1016/J.Bpj.2009.12.3857 |
0.727 |
|
| 2010 |
Chen Q, Cheng MH, Stevenson H, Xu Y, Tang P. Multisite Binding of Anesthetics to GLIC, a Pentameric Ligand-Gated Ion Channel Biophysical Journal. 98: 702a-703a. DOI: 10.1016/J.Bpj.2009.12.3855 |
0.718 |
|
| 2010 |
Mowrey DD, Liu LT, Willenbring D, Haddadian EJ, Xu Y, Tang P. Why Is α4β2 Nachr More Sensitive to Volatile Anesthetics Than α7 Nachr? Biophysical Journal. 98: 38a. DOI: 10.1016/J.Bpj.2009.12.218 |
0.724 |
|
| 2009 |
Liu LT, Willenbring D, Xu Y, Tang P. General anesthetic binding to neuronal alpha4beta2 nicotinic acetylcholine receptor and its effects on global dynamics. The Journal of Physical Chemistry. B. 113: 12581-9. PMID 19697903 DOI: 10.1021/Jp9039513 |
0.735 |
|
| 2009 |
Xu Y, Liachenko SM, Tang P, Chan PH. Faster recovery of cerebral perfusion in SOD1-overexpressed rats after cardiac arrest and resuscitation. Stroke; a Journal of Cerebral Circulation. 40: 2512-8. PMID 19461023 DOI: 10.1161/Strokeaha.109.548453 |
0.603 |
|
| 2009 |
Cheng MH, Xu Y, Tang P. Anionic lipid and cholesterol interactions with alpha4beta2 nAChR: insights from MD simulations. The Journal of Physical Chemistry. B. 113: 6964-70. PMID 19419220 DOI: 10.1021/Jp900714B |
0.698 |
|
| 2009 |
Cheng MH, Haddadian E, Xu Y, Tang P. Interactions between POPA and a4b2 nAChR: Insight from MD Simulations Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.3225 |
0.724 |
|
| 2009 |
Cui T, Tang P, Saven JG, Eckenhoff RG, Xu Y. NMR Structure of Water-Solubilized Transmembrane Domain of Nicotinic Acetylcholine Receptor Biophysical Journal. 96: 429a. DOI: 10.1016/J.Bpj.2008.12.2197 |
0.721 |
|
| 2009 |
Ma D, Jia Y, Tang P, Xu Y. Structure and Dynamics of TM Domains of Human Glycine Receptor in LPPG Micelles Biophysical Journal. 96: 195a. DOI: 10.1016/J.Bpj.2008.12.1045 |
0.711 |
|
| 2008 |
Ma D, Tillman TS, Tang P, Meirovitch E, Eckenhoff R, Carnini A, Xu Y. NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA. Proceedings of the National Academy of Sciences of the United States of America. 105: 16537-42. PMID 18948596 DOI: 10.1073/Pnas.0805501105 |
0.687 |
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| 2008 |
Haddadian EJ, Cheng MH, Coalson RD, Xu Y, Tang P. In silico models for the human alpha4beta2 nicotinic acetylcholine receptor. The Journal of Physical Chemistry. B. 112: 13981-90. PMID 18847252 DOI: 10.1021/Jp804868S |
0.731 |
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| 2008 |
Canlas CG, Cui T, Li L, Xu Y, Tang P. Anesthetic modulation of protein dynamics: insight from an NMR study. The Journal of Physical Chemistry. B. 112: 14312-8. PMID 18821786 DOI: 10.1021/Jp805952W |
0.694 |
|
| 2008 |
Canlas CG, Ma D, Tang P, Xu Y. Residual dipolar coupling measurements of transmembrane proteins using aligned low-q bicelles and high-resolution magic angle spinning NMR spectroscopy. Journal of the American Chemical Society. 130: 13294-300. PMID 18788737 DOI: 10.1021/Ja802578Z |
0.653 |
|
| 2008 |
Ma D, Brandon NR, Cui T, Bondarenko V, Canlas C, Johansson JS, Tang P, Xu Y. Four-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analyses. Biophysical Journal. 94: 4454-63. PMID 18310240 DOI: 10.1529/biophysj.107.117838 |
0.693 |
|
| 2008 |
Cui T, Bondarenko V, Ma D, Canlas C, Brandon NR, Johansson JS, Xu Y, Tang P. Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics. Biophysical Journal. 94: 4464-72. PMID 18310239 DOI: 10.1529/Biophysj.107.117853 |
0.719 |
|
| 2008 |
Bondarenko V, Yushmanov VE, Xu Y, Tang P. NMR study of general anesthetic interaction with nAChR beta2 subunit. Biophysical Journal. 94: 1681-8. PMID 17993502 DOI: 10.1529/Biophysj.107.116772 |
0.699 |
|
| 2008 |
Ma D, Xu Y, Tillman T, Tang P, Meirovitch E, Eckenhoff R, Carnini A. Solubilization of transmembrane proteins in water: structural studies of a water-soluble analogue of the potassium channel KcsA Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15677 |
0.666 |
|
| 2007 |
Cheng MH, Liu LT, Saladino AC, Xu Y, Tang P. Molecular dynamics simulations of ternary membrane mixture: phosphatidylcholine, phosphatidic acid, and cholesterol. The Journal of Physical Chemistry. B. 111: 14186-92. PMID 18052271 DOI: 10.1021/Jp075467B |
0.656 |
|
| 2007 |
Szarecka A, Xu Y, Tang P. Dynamics of heteropentameric nicotinic acetylcholine receptor: implications of the gating mechanism. Proteins. 68: 948-60. PMID 17546671 DOI: 10.1002/Prot.21462 |
0.708 |
|
| 2007 |
Szarecka A, Xu Y, Tang P. Dynamics of firefly luciferase inhibition by general anesthetics: Gaussian and anisotropic network analyses. Biophysical Journal. 93: 1895-905. PMID 17513367 DOI: 10.1529/Biophysj.106.102780 |
0.674 |
|
| 2007 |
Bondarenko V, Xu Y, Tang P. Structure of the first transmembrane domain of the neuronal acetylcholine receptor beta2 subunit. Biophysical Journal. 92: 1616-22. PMID 17142275 DOI: 10.1529/Biophysj.106.095364 |
0.703 |
|
| 2007 |
Ma D, Brandon NR, Cui T, Bondarenko V, Canlas C, Johansson JS, Tang P, Xu Y. Structural and Dynamical Analysis of a Four-Alpha-Helix Bundle with Designed Anesthetic Binding Pockets Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2I7U/Pdb |
0.674 |
|
| 2006 |
Liu Z, Xu Y, Tang P. Steered molecular dynamics simulations of Na+ permeation across the gramicidin A channel. The Journal of Physical Chemistry. B. 110: 12789-95. PMID 16800614 DOI: 10.1021/Jp060688N |
0.702 |
|
| 2005 |
Yonkunas MJ, Xu Y, Tang P. Anesthetic interaction with ketosteroid isomerase: insights from molecular dynamics simulations. Biophysical Journal. 89: 2350-6. PMID 16040747 DOI: 10.1529/Biophysj.105.063396 |
0.688 |
|
| 2005 |
Ma D, Liu Z, Li L, Tang P, Xu Y. Structure and dynamics of the second and third transmembrane domains of human glycine receptor. Biochemistry. 44: 8790-800. PMID 15952785 DOI: 10.1021/Bi050256N |
0.697 |
|
| 2005 |
Liu Z, Xu Y, Tang P. Molecular dynamics simulations of C2F6 effects on gramicidin A: implications of the mechanisms of general anesthesia. Biophysical Journal. 88: 3784-91. PMID 15764669 DOI: 10.1529/Biophysj.104.055566 |
0.705 |
|
| 2005 |
Saladino AC, Xu Y, Tang P. Homology modeling and molecular dynamics simulations of transmembrane domain structure of human neuronal nicotinic acetylcholine receptor. Biophysical Journal. 88: 1009-17. PMID 15574706 DOI: 10.1529/Biophysj.104.053421 |
0.701 |
|
| 2004 |
Liu Z, Xu Y, Saladino AC, Wymore T, Tang P. Parametrization of 2-bromo-2-chloro-1,1,1-trifluoroethane (halothane) and hexafluoroethane for nonbonded interactions Journal of Physical Chemistry A. 108: 781-786. DOI: 10.1021/Jp0368482 |
0.615 |
|
| 2003 |
Yushmanov VE, Xu Y, Tang P. NMR structure and dynamics of the second transmembrane domain of the neuronal acetylcholine receptor beta 2 subunit. Biochemistry. 42: 13058-65. PMID 14596621 DOI: 10.1021/Bi0350396 |
0.679 |
|
| 2003 |
Liachenko S, Tang P, Xu Y. Deferoxamine improves early postresuscitation reperfusion after prolonged cardiac arrest in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 574-81. PMID 12771572 DOI: 10.1097/01.Wcb.0000057742.00152.3F |
0.619 |
|
| 2003 |
Yushmanov VE, Mandal PK, Liu Z, Tang P, Xu Y. NMR structure and backbone dynamics of the extended second transmembrane domain of the human neuronal glycine receptor alpha1 subunit. Biochemistry. 42: 3989-95. PMID 12667090 DOI: 10.1021/Bi026767G |
0.677 |
|
| 2003 |
Yushmanov V, Mandal P, Liu Z, Tang P, Xu Y. NMR Structure of the Extended Second Transmembrane Domain of the Human Neuronal Glycine Receptor alpha1 Subunit in SDS Micelles Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5607 |
0.674 |
|
| 2002 |
Homanics GE, Xu Y, Tang P. Integrated approaches to the action of general anesthetics and alcohol. Physiology & Behavior. 77: 495-9. PMID 12526989 DOI: 10.1016/S0031-9384(02)00910-1 |
0.602 |
|
| 2002 |
Tang P, Xu Y. Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia. Proceedings of the National Academy of Sciences of the United States of America. 99: 16035-40. PMID 12438684 DOI: 10.1073/Pnas.252522299 |
0.704 |
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| 2002 |
Xu Y, Yushmanov VE, Tang P. NMR studies of drug interaction with membranes and membrane-associated proteins. Bioscience Reports. 22: 175-96. PMID 12428900 DOI: 10.1023/A:1020182404940 |
0.639 |
|
| 2002 |
Tang P, Mandal PK, Xu Y. NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating. Biophysical Journal. 83: 252-62. PMID 12080117 DOI: 10.1016/S0006-3495(02)75166-7 |
0.724 |
|
| 2002 |
Wang L, Yushmanov VE, Liachenko SM, Tang P, Hamilton RL, Xu Y. Late reversal of cerebral perfusion and water diffusion after transient focal ischemia in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 253-61. PMID 11891430 DOI: 10.1097/00004647-200203000-00002 |
0.611 |
|
| 2002 |
Xu Y, Liachenko S, Tang P. Dependence of early cerebral reperfusion and long-term outcome on resuscitation efficiency after cardiac arrest in rats. Stroke; a Journal of Cerebral Circulation. 33: 837-43. PMID 11872912 DOI: 10.1161/Hs0302.104198 |
0.6 |
|
| 2002 |
Yushmanov VE, Wang L, Liachenko S, Tang P, Xu Y. ADC characterization of region-specific response to cerebral perfusion deficit in rats by MRI at 9.4 T. Magnetic Resonance in Medicine. 47: 562-70. PMID 11870844 DOI: 10.1002/Mrm.10103 |
0.621 |
|
| 2001 |
Liachenko S, Tang P, Hamilton RL, Xu Y. Regional dependence of cerebral reperfusion after circulatory arrest in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 1320-9. PMID 11702047 DOI: 10.1097/00004647-200111000-00008 |
0.627 |
|
| 2001 |
Tang P, Zubrzycki I, Xu Y. Ab initio calculation of structures and properties of halogenated general anesthetics: halothane and sevoflurane Journal of Computational Chemistry. 22: 802-802. DOI: 10.1002/jcc.1044 |
0.605 |
|
| 2000 |
Tang P, Eckenhoff RG, Xu Y. General anesthetic binding to gramicidin A: the structural requirements. Biophysical Journal. 78: 1804-9. PMID 10733961 DOI: 10.1016/S0006-3495(00)76730-0 |
0.696 |
|
| 2000 |
Xu Y, Seto T, Tang P, Firestone L. NMR study of volatile anesthetic binding to nicotinic acetylcholine receptors. Biophysical Journal. 78: 746-51. PMID 10653787 DOI: 10.1016/S0006-3495(00)76632-X |
0.686 |
|
| 2000 |
Tang P, Zubrzycki I, Xu Y. Room 309, 10/18/2000 9: 00 AM - 10: 30 AM (PD) A Closer Look at Volatile Anesthetic Interaction with Ion Channel: One Femtosecond a Time Anesthesiology. 93: A-145. DOI: 10.1097/00000542-200009001-00145 |
0.658 |
|
| 2000 |
Zubrzycki I, Xu Y, Tang P. Room 302, 10/16/2000 9: 00 AM - 10: 30 AM (PD) Creator's View of Anesthetics: Anesthesiology. 93: A-121. DOI: 10.1097/00000542-200009001-00121 |
0.593 |
|
| 2000 |
Zubrzycki IZ, Xu Y, Madrid M, Tang P. Molecular dynamics simulations of a fully hydrated dimyristoylphosphatidylcholine membrane in liquid-crystalline phase Journal of Chemical Physics. 112: 3437-3441. DOI: 10.1063/1.480924 |
0.634 |
|
| 1999 |
Tang P, Hu J, Liachenko S, Xu Y. Distinctly different interactions of anesthetic and nonimmobilizer with transmembrane channel peptides. Biophysical Journal. 77: 739-46. PMID 10423422 DOI: 10.1016/S0006-3495(99)76928-6 |
0.66 |
|
| 1999 |
Liachenko S, Tang P, Somogyi GT, Xu Y. Concentration-dependent isoflurane effects on depolarization-evoked glutamate and GABA outflows from mouse brain slices. British Journal of Pharmacology. 127: 131-8. PMID 10369465 DOI: 10.1038/Sj.Bjp.0702543 |
0.618 |
|
| 1999 |
Tang P, Simplaceanu V, Xu Y. Structural consequences of anesthetic and nonimmobilizer interaction with gramicidin A channels. Biophysical Journal. 76: 2346-50. PMID 10233053 DOI: 10.1016/S0006-3495(99)77391-1 |
0.704 |
|
| 1999 |
Xu Y, Tang P, Liachenko S. Unifying characteristics of sites of anesthetic action revealed by combined use of anesthetics and non-anesthetics. Toxicology Letters. 347-52. PMID 10049163 DOI: 10.1016/S0378-4274(98)00205-7 |
0.697 |
|
| 1998 |
Tang P, Liachenko S, Melick JA, Xu Y. [31P]/[1H] nuclear magnetic resonance study of mitigating effects of GYKI 52466 on kainate-induced metabolic impairment in perfused rat cerebrocortical slices. Epilepsia. 39: 577-83. PMID 9637598 DOI: 10.1111/J.1528-1157.1998.Tb01424.X |
0.617 |
|
| 1998 |
Liachenko S, Tang P, Hamilton RL, Xu Y. A reproducible model of circulatory arrest and remote resuscitation in rats for NMR investigation. Stroke; a Journal of Cerebral Circulation. 29: 1229-38; discussion . PMID 9626299 DOI: 10.1161/01.Str.29.6.1229 |
0.625 |
|
| 1998 |
Liachenko S, Tang P, Somogyi GT, Xu Y. Comparison of anaesthetic and non-anaesthetic effects on depolarization-evoked glutamate and GABA release from mouse cerebrocortical slices. British Journal of Pharmacology. 123: 1274-80. PMID 9559915 DOI: 10.1038/Sj.Bjp.0701728 |
0.632 |
|
| 1998 |
Liachenko S, Tang P, Somogyi GT, Xu Y. DIFFERENT ISOFLURANE EC50 FOR INHIBITION OF RELEASE AND RE-UPTAKE OF NEUROTRANSMITTERS Anesthesiology. 89: 125A. DOI: 10.1097/00000542-199809040-00029 |
0.605 |
|
| 1997 |
Tang P, Yan B, Xu Y. Different distribution of fluorinated anesthetics and nonanesthetics in model membrane: a 19F NMR study. Biophysical Journal. 72: 1676-82. PMID 9083671 DOI: 10.1016/S0006-3495(97)78813-1 |
0.643 |
|
| 1997 |
Xu Y, Tang P. Amphiphilic sites for general anesthetic action? Evidence from 129Xe-[1H] intermolecular nuclear Overhauser effects. Biochimica Et Biophysica Acta. 1323: 154-162. PMID 9030222 DOI: 10.1016/S0005-2736(96)00184-8 |
0.666 |
|
| 1997 |
Xu Y, Liachenko S, Tang P. A604 AN OUTCOME MODEL OF PROLONGED CARDIAC ARREST AND RESUSCITATION FOR CEREBRAL PERFUSION MRI Anesthesiology. 87: 604A. DOI: 10.1097/00000542-199709001-00604 |
0.603 |
|
| 1997 |
Tang P, Liachenko S, Xu Y. A601 BRAIN ADC MAPPING AFTER RESUSCITATION FROM ASPHYXIAL CARDIAC ARREST Anesthesiology. 87: 601A. DOI: 10.1097/00000542-199709001-00601 |
0.599 |
|
| 1997 |
Liachenko S, Tang P, Somogyi GT, Xu Y. A331 ANESTHETIC AND NONANESTHETIC EFFECTS ON GLUTAMATE AND GABA RELEASE Anesthesiology. 87: 331A. DOI: 10.1097/00000542-199709001-00331 |
0.608 |
|
| 1996 |
Xu Y, Tang P, Firestone L, Zhang TT. 19F nuclear magnetic resonance investigation of stereoselective binding of isoflurane to bovine serum albumin. Biophysical Journal. 70: 532-8. PMID 8770230 DOI: 10.1016/S0006-3495(96)79599-1 |
0.676 |
|
| 1995 |
Xu Y, Tang P, Zhang W, Firestone L, Winter PM. Fluorine-19 nuclear magnetic resonance imaging and spectroscopy of sevoflurane uptake, distribution, and elimination in rat brain. Anesthesiology. 83: 766-74. PMID 7574056 DOI: 10.1097/00000542-199510000-00016 |
0.628 |
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