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Ian B. Seiple, Ph.D. - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Website:
http://www.seiplegroup.com
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cai L, Seiple IB, Li Q. Modular Chemical Synthesis of Streptogramin and Lankacidin Antibiotics. Accounts of Chemical Research. PMID 33792282 DOI: 10.1021/acs.accounts.0c00894  0.367
2020 Boyce JH, Dang B, Ary B, Edmondson Q, Craik CS, DeGrado WF, Seiple IB. Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates. Journal of the American Chemical Society. PMID 33301681 DOI: 10.1021/jacs.0c06987  0.702
2020 Sundaram A, Chen C, Isik Reed N, Liu S, Ki Yeon S, McIntosh J, Tang YZ, Yang H, Adler M, Beresis R, Seiple IB, Sheppard D, DeGrado WF, Jo H. Dual antagonists of α5β1/ αvβ1 integrin for airway hyperresponsiveness. Bioorganic & Medicinal Chemistry Letters. 127578. PMID 33007395 DOI: 10.1016/j.bmcl.2020.127578  0.368
2020 Cai L, Yao Y, Yeon SK, Seiple IB. Modular approaches to lankacidin antibiotics. Journal of the American Chemical Society. PMID 32786797 DOI: 10.1021/Jacs.0C06648  0.406
2019 Li Q, Seiple IB. A concise route to virginiamycin M2. Tetrahedron. 75: 3309-3318. PMID 32764837 DOI: 10.1016/J.Tet.2019.04.060  0.442
2018 Yao Y, Cai L, Seiple IB. Synthesis, Structural Reassignment, and Antibacterial Evaluation of 2,18-Seco-Lankacidinol B. Angewandte Chemie (International Ed. in English). PMID 30133094 DOI: 10.1002/Anie.201808612  0.416
2017 Li Q, Seiple IB. Modular, Scalable Synthesis of Group A Streptogramin Antibiotics. Journal of the American Chemical Society. PMID 28902996 DOI: 10.1021/Jacs.7B08577  0.451
2016 Seiple IB, Zhang Z, Jakubec P, Langlois-Mercier A, Wright PM, Hog DT, Yabu K, Allu SR, Fukuzaki T, Carlsen PN, Kitamura Y, Zhou X, Condakes ML, Szczypiński FT, Green WD, et al. A platform for the discovery of new macrolide antibiotics. Nature. 533: 338-45. PMID 27193679 DOI: 10.1038/Nature17967  0.717
2015 Seiple IB, Hog DT, Myers AG. Practical Protocols for the Preparation of Highly Enantioenriched Silyl Ethers of (R)-3-Hydroxypentan-2-one, Building Blocks for the Synthesis of Macrolide Antibiotics Synlett. DOI: 10.1055/S-0035-1560972  0.547
2014 Wright PM, Seiple IB, Myers AG. The evolving role of chemical synthesis in antibacterial drug discovery. Angewandte Chemie (International Ed. in English). 53: 8840-69. PMID 24990531 DOI: 10.1002/Anie.201310843  0.586
2014 Seiple IB, Mercer JA, Sussman RJ, Zhang Z, Myers AG. Stereocontrolled synthesis of syn-β-Hydroxy-α-amino acids by direct aldolization of pseudoephenamine glycinamide. Angewandte Chemie (International Ed. in English). 53: 4642-7. PMID 24692320 DOI: 10.1002/Anie.201400928  0.574
2014 Wright PM, Seiple IB, Myers AG. ChemInform Abstract: The Evolving Role of Chemical Synthesis in Antibacterial Drug Discovery Cheminform. 45: no-no. DOI: 10.1002/chin.201446263  0.508
2014 Seiple IB, Mercer JAM, Sussman RJ, Zhang Z, Myers AG. ChemInform Abstract: Stereocontrolled Synthesis of syn-β-Hydroxy-α-amino Acids by Direct Aldolization of Pseudoephenamine Glycinamide. Cheminform. 45: no-no. DOI: 10.1002/chin.201443029  0.476
2014 Wright PM, Seiple IB, Myers AG. Zur Rolle der chemischen Synthese in der Entwicklung antibakterieller Wirkstoffe Angewandte Chemie. 126: 8984-9014. DOI: 10.1002/Ange.201310843  0.471
2012 Lansdell TA, Hewlett NM, Skoumbourdis AP, Fodor MD, Seiple IB, Su S, Baran PS, Feldman KS, Tepe JJ. Palau'amine and related oroidin alkaloids dibromophakellin and dibromophakellstatin inhibit the human 20S proteasome. Journal of Natural Products. 75: 980-5. PMID 22591513 DOI: 10.1021/Np300231F  0.506
2012 Köck M, Schmidt G, Seiple IB, Baran PS. Configurational analysis of tetracyclic dimeric pyrrole-imidazole alkaloids using a floating chirality approach. Journal of Natural Products. 75: 127-30. PMID 22332969 DOI: 10.1021/Np200514G  0.556
2011 Seiple IB, Su S, Young IS, Nakamura A, Yamaguchi J, Jørgensen L, Rodriguez RA, O'Malley DP, Gaich T, Köck M, Baran PS. Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines. Journal of the American Chemical Society. 133: 14710-26. PMID 21861522 DOI: 10.1021/Ja2047232  0.713
2011 Ji Y, Brueckl T, Baxter RD, Fujiwara Y, Seiple IB, Su S, Blackmond DG, Baran PS. Innate C-H trifluoromethylation of heterocycles. Proceedings of the National Academy of Sciences of the United States of America. 108: 14411-5. PMID 21844378 DOI: 10.1073/Pnas.1109059108  0.497
2011 Fujiwara Y, Domingo V, Seiple IB, Gianatassio R, Del Bel M, Baran PS. Practical C-H functionalization of quinones with boronic acids. Journal of the American Chemical Society. 133: 3292-5. PMID 21341741 DOI: 10.1021/Ja111152Z  0.534
2010 Seiple IB, Su S, Rodriguez RA, Gianatassio R, Fujiwara Y, Sobel AL, Baran PS. Direct C-H arylation of electron-deficient heterocycles with arylboronic acids. Journal of the American Chemical Society. 132: 13194-6. PMID 20812741 DOI: 10.1021/Ja1066459  0.521
2010 Seiple IB, Su S, Young IS, Lewis CA, Yamaguchi J, Baran PS. Total synthesis of palau'amine. Angewandte Chemie (International Ed. in English). 49: 1095-8. PMID 20041464 DOI: 10.1002/Anie.200907112  0.759
2010 Baran P, Seiple I, Su S, Rodriguez R, Gianatassio R, Fujiwara Y, Sobel A. C-H Arylation of N-Heterocycles with Arylboronic Acids Synfacts. 2010: 1413-1413. DOI: 10.1055/S-0030-1258856  0.472
2010 Seiple IB, Su S, Young IS, Lewis CA, Yamaguchi J, Baran PS. Synthesis of Palau’amine Synfacts. 2010: 501-501. DOI: 10.1055/S-0029-1219711  0.714
2010 Seiple I, Su S, Young I, Lewis C, Yamaguchi J, Baran P. Cover Picture: Total Synthesis of Palau’amine (Angew. Chem. Int. Ed. 6/2010) Angewandte Chemie International Edition. 49: 989-989. DOI: 10.1002/Anie.200907224  0.688
2010 Seiple I, Su S, Young I, Lewis C, Yamaguchi J, Baran P. Titelbild: Total Synthesis of Palau’amine (Angew. Chem. 6/2010) Angewandte Chemie. 122: 1003-1003. DOI: 10.1002/Ange.200907224  0.715
2010 Su S, Seiple IB, Young IS, Baran PS. Total syntheses of (±)-massadine and massadine chloride Chemtracts. 23: 30-32.  0.406
2009 Su S, Seiple IB, Young IS, Baran PS. Syntheses of ()-Massadine and Massadine Chloride Synfacts. 2009: 473-473. DOI: 10.1055/S-0028-1088176  0.536
2008 Su S, Seiple IB, Young IS, Baran PS. Total syntheses of (+/-)-massadine and massadine chloride. Journal of the American Chemical Society. 130: 16490-1. PMID 19049446 DOI: 10.1021/Ja8074852  0.523
2008 O'Malley DP, Yamaguchi J, Young IS, Seiple IB, Baran PS. Total synthesis of (+/-)-axinellamines A and B. Angewandte Chemie (International Ed. in English). 47: 3581-3. PMID 18357612 DOI: 10.1002/Anie.200801138  0.692
2008 Yamaguchi J, Seiple IB, Young IS, O'Malley DP, Maue M, Baran PS. Synthesis of 1,9-dideoxy-pre-axinellamine. Angewandte Chemie (International Ed. in English). 47: 3578-80. PMID 18357598 DOI: 10.1002/Anie.200705913  0.727
2008 Baran P, O’Malley D, Yamaguchi J, Young I, Seiple I. Synthesis of ()-Axinellamines A and B Synfacts. 2008: 1136-1136. DOI: 10.1055/S-0028-1083408  0.555
2008 Yamaguchi J, Seiple IB, Young IS, O'Malley DP, Maue M, Baran PS. ChemInform Abstract: Synthesis of 1,9-Dideoxy-pre-axinellamine. Cheminform. 39. DOI: 10.1002/chin.200837183  0.562
2008 O'Malley D, Yamaguchi J, Young I, Seiple I, Baran P. Inside Cover: Total Synthesis of (±)-Axinellamines A and B (Angew. Chem. Int. Ed. 19/2008) Angewandte Chemie International Edition. 47: 3470-3470. DOI: 10.1002/Anie.200890085  0.527
2008 O'Malley D, Yamaguchi J, Young I, Seiple I, Baran P. Innentitelbild: Total Synthesis of (±)-Axinellamines A and B (Angew. Chem. 19/2008) Angewandte Chemie. 120: 3522-3522. DOI: 10.1002/Ange.200890085  0.525
2007 Köck M, Grube A, Seiple IB, Baran PS. The pursuit of palau'amine. Angewandte Chemie (International Ed. in English). 46: 6586-94. PMID 17724780 DOI: 10.1002/Anie.200701798  0.575
2007 Trauner D, Liang G, Xu Y, Seiple I. Synthesis of Taiwaniaquinoids Synfacts. 2007: 0126-0126. DOI: 10.1055/S-2006-955768  0.594
2007 Koeck M, Grube A, Seiple IB, Baran PS. The Pursuit of Palau′amine Cheminform. 38. DOI: 10.1002/chin.200748234  0.338
2007 Köck M, Grube A, Seiple I, Baran P. Die Jagd auf Palau'amin Angewandte Chemie. 119: 6706-6714. DOI: 10.1002/Ange.200701798  0.48
2006 Liang G, Xu Y, Seiple IB, Trauner D. Synthesis of taiwaniaquinoids via Nazarov triflation. Journal of the American Chemical Society. 128: 11022-3. PMID 16925409 DOI: 10.1021/Ja062505G  0.549
2005 Liang G, Seiple IB, Trauner D. Stereoselective syntheses of the bioactive polypropionates aureothin, N-acetylaureothamine, and aureonitrile. Organic Letters. 7: 2837-9. PMID 15987149 DOI: 10.1021/Ol050703R  0.49
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