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Ernst Heinrich Niggli - Publications

Affiliations: 
1947-1955 Geology Leiden University, Leiden, Netherlands 
 1955-1987 Universität Bern 
Area:
Petrology, Crystallography and Mineralogy
Website:
http://www.dwc.knaw.nl/biografie/pmknaw/?pagetype=authorDetail&aId=PE00002084
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119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lopez R, Janicek R, Fernandez-Tenorio M, Courtehoux M, Matas L, Gerbaud P, Gomez AM, Egger M, Niggli E. Uptake-leak balance of SR Ca determines arrhythmogenic potential of RyR2 cardiomyocytes. Journal of Molecular and Cellular Cardiology. 170: 1-14. PMID 35644481 DOI: 10.1016/j.yjmcc.2022.05.011  0.575
2021 Janicek R, Agarwal H, Gómez AM, Egger M, Ellis-Davies GCR, Niggli E. Local recovery of cardiac calcium-induced calcium release interrogated by ultra-effective, two-photon uncaging of calcium. The Journal of Physiology. PMID 34245001 DOI: 10.1113/JP281482  0.595
2021 Yin L, Zahradnikova A, Rizzetto R, Boncompani S, Rabesahala de Meritens C, Zhang Y, Joanne P, Marques Sule E, Aguilar-Torres Y, Fernandez-Tenorio M, Villejoubert O, Li L, Wang YY, Mateo P, Nicolas V, ... ... Niggli E, et al. Impaired Binding to Junctophilin2 and Nanostructural Alteration in CPVT Mutation. Circulation Research. PMID 34111951 DOI: 10.1161/CIRCRESAHA.121.319094  0.537
2020 Potenza DM, Janicek R, Fernandez-Tenorio M, Niggli E. Activation of endogenous protein phosphatase 1 enhances the calcium sensitivity of the ryanodine receptor type 2 in murine ventricular cardiomyocytes. The Journal of Physiology. PMID 31943206 DOI: 10.1113/Jp278951  0.557
2020 Lopez Dicuru RJ, Fernandez-Tenorio M, Janicek R, Gomez AM, Niggli E. SERCA Stimulation Triggers Arrhythmogenic Ca2+ Events in Mouse Cardiomyocytes Harboring the RyR2R420Q+/- Mutation Biophysical Journal. 118: 254a. DOI: 10.1016/J.Bpj.2019.11.1482  0.555
2019 Niggli E, Fernandez-Tenorio M. Simultaneous Recording of Subcellular Ca Signals from the Cytosol and Sarco/Endoplasmic Reticulum: Compartmentalized Dye Loading, Imaging, and Analysis. Methods in Molecular Biology (Clifton, N.J.). 1929: 53-71. PMID 30710267 DOI: 10.1007/978-1-4939-9030-6_5  0.694
2018 Illaste A, Wullschleger M, Fernandez-Tenorio M, Niggli E, Egger M. Automatic Detection and Classification of Ca Release Events in Line- and Frame-Scan Images. Biophysical Journal. PMID 30638961 DOI: 10.1016/J.Bpj.2018.12.013  0.61
2018 Potenza DM, Janicek R, Fernandez-Tenorio M, Camors E, Ramos-Mondragón R, Valdivia HH, Niggli E. Phosphorylation of the ryanodine receptor 2 at serine 2030 is required for a complete β-adrenergic response. The Journal of General Physiology. PMID 30541771 DOI: 10.1085/Jgp.201812155  0.639
2018 Fernandez-Tenorio M, Niggli E. Stabilization of Ca signaling in cardiac muscle by stimulation of SERCA. Journal of Molecular and Cellular Cardiology. PMID 29715473 DOI: 10.1016/J.Yjmcc.2018.04.015  0.654
2017 Rizzetto R, Fernandez-Tenorio M, Zahradnikova A, Boncompani S, Marqués-Sulé E, Yi Wang Y, Benitah J, Zorio E, Protasi F, Niggli E, Gomez AM. Functional Effects of the RyR 2 R420Q Catecholaminergic Ventricular Polymorphic Tachycardia in Mouse Cardiomyocytes Biophysical Journal. 112: 94a. DOI: 10.1016/J.Bpj.2016.11.551  0.661
2017 Janicek R, Agarwal H, Ellis-Davies GC, Niggli E. Local Recovery of CICR Probed by Ultra-Effective Calcium Uncaging Biophysical Journal. 112: 231a. DOI: 10.1016/J.Bpj.2016.11.1271  0.669
2016 Plaisance I, Perruchoud S, Fernandez-Tenorio M, Gonzales C, Ounzain S, Ruchat P, Nemir M, Niggli E, Pedrazzini T. Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression. Jacc. Basic to Translational Science. 1: 472-493. PMID 29707678 DOI: 10.1016/J.Jacbts.2016.06.008  0.31
2016 Fernandez-Tenorio M, Niggli E. Real-time intra-store confocal Ca(2+) imaging in isolated mouse cardiomyocytes. Cell Calcium. PMID 27431464 DOI: 10.1016/J.Ceca.2016.07.002  0.701
2016 Agarwal HK, Janicek R, Chi SH, Perry JW, Niggli E, Ellis-Davies GC. Calcium Uncaging with Visible Light. Journal of the American Chemical Society. PMID 26974387 DOI: 10.1021/Jacs.5B11606  0.621
2016 Janicek R, Agarwal HK, Ellis-Davies GC, Niggli E. One and Two-Photon Calcium Uncaging with Visible Light in Cardiac Myocytes Biophysical Journal. 110: 432a. DOI: 10.1016/J.Bpj.2015.11.2335  0.667
2016 Michele Potenza D, Fernandez-Tenorio M, Niggli E. Protein Phosphatase-1 Increases Calcium Spark Frequency in Murine Cardiomyocytes via Modulation of RyR2 Phosphorylation Biophysical Journal. 110: 269a-270a. DOI: 10.1016/J.Bpj.2015.11.1467  0.633
2015 Poláková E, Illaste A, Niggli E, Sobie EA. Maximal acceleration of Ca2+ release refractoriness by β-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes. The Journal of Physiology. 593: 1495-507. PMID 25772298 DOI: 10.1113/Jphysiol.2014.278051  0.435
2015 Niggli E. IP3 and Ca(2+) signals in the heart: boost them or bust them? The Journal of Physiology. 593: 1385-6. PMID 25772293 DOI: 10.1113/Jphysiol.2014.287987  0.697
2015 Lorin C, Vögeli I, Niggli E. Dystrophic cardiomyopathy: role of TRPV2 channels in stretch-induced cell damage. Cardiovascular Research. 106: 153-62. PMID 25616416 DOI: 10.1093/Cvr/Cvv021  0.434
2015 Fernandez-Tenorio M, Niggli E. Opposite Changes of Ca2+ Wave Threshold and Fractional SR Ca2+ Release during SERCA Stimulation in Cardiomyocytes Biophysical Journal. 108: 263a. DOI: 10.1016/J.Bpj.2014.11.1450  0.676
2014 Shirokova N, Kang C, Fernandez-Tenorio M, Wang W, Wang Q, Wehrens XH, Niggli E. Oxidative stress and ca(2+) release events in mouse cardiomyocytes. Biophysical Journal. 107: 2815-27. PMID 25517148 DOI: 10.1016/J.Bpj.2014.10.054  0.624
2014 Illaste A, Wullschleger M, Fernandez-Tenorio M, Egger M, Niggli E. Extracting Detailed Ca2+ Signaling Information from Noisy Confocal Images Biophysical Journal. 106: 532a. DOI: 10.1016/J.Bpj.2013.11.2970  0.514
2014 Wullschleger M, Illaste A, Niggli E, Egger M. Characterization of Calcium Release Events Evoked by InsP3R Activation in Intact and Permeabilized Atrial Myocytes Biophysical Journal. 106: 532a. DOI: 10.1016/J.Bpj.2013.11.2969  0.68
2014 Illaste A, Polakova E, Niggli E, Sobie EA. Activity of Both PKA and Camkii is Required for Maximal RyR Sensitivity Under Beta-Adrenergic Stimulation Biophysical Journal. 106: 431a. DOI: 10.1016/J.Bpj.2013.11.2426  0.377
2014 Fernandez-Tenorio M, Niggli E. Serca Stimulation Increases Intra-Sr Ca2+Threshold for Ca2+ Waves in Cadiomyocytes Biophysical Journal. 106: 323a. DOI: 10.1016/J.Bpj.2013.11.1862  0.641
2013 Gutierrez DA, Fernandez-Tenorio M, Ogrodnik J, Niggli E. NO-dependent CaMKII activation during β-adrenergic stimulation of cardiac muscle. Cardiovascular Research. 100: 392-401. PMID 23963842 DOI: 10.1093/Cvr/Cvt201  0.625
2013 Kyrychenko S, Poláková E, Kang C, Pocsai K, Ullrich ND, Niggli E, Shirokova N. Hierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathy. Cardiovascular Research. 97: 666-75. PMID 23263329 DOI: 10.1093/Cvr/Cvs425  0.634
2013 Shirokova N, Niggli E. Cardiac phenotype of Duchenne Muscular Dystrophy: insights from cellular studies. Journal of Molecular and Cellular Cardiology. 58: 217-24. PMID 23261966 DOI: 10.1016/J.Yjmcc.2012.12.009  0.322
2013 Niggli E, Ullrich ND, Gutierrez D, Kyrychenko S, Poláková E, Shirokova N. Posttranslational modifications of cardiac ryanodine receptors: Ca(2+) signaling and EC-coupling. Biochimica Et Biophysica Acta. 1833: 866-75. PMID 22960642 DOI: 10.1016/J.Bbamcr.2012.08.016  0.64
2013 Fernandez-Tenorio M, Gutierrez D, Niggli E. Improved Protocol to Record Sarcoplasmic Reticulum Calcium Concentrations in Mouse Cardiomyocytes Biophysical Journal. 104: 607a. DOI: 10.1016/J.Bpj.2012.11.3366  0.696
2013 Polakova E, Illaste A, Niggli E, Sobie EA. Factors Influencing Ca2+ Spark Refractoriness in Mouse Biophysical Journal. 104: 438a. DOI: 10.1016/J.Bpj.2012.11.2435  0.686
2013 Gutierrez D, Fernandez-Tenorio M, Ogrodnik J, Niggli E. Direct CaMKII Activation by Endogenous Nitric Oxide Modulates Calcium Spark Frequency in Cardiomyocytes Biophysical Journal. 104: 361a. DOI: 10.1016/J.Bpj.2012.11.2006  0.461
2012 Ullrich ND, Valdivia HH, Niggli E. PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity. Journal of Molecular and Cellular Cardiology. 53: 33-42. PMID 22487381 DOI: 10.1016/J.Yjmcc.2012.03.015  0.673
2012 Gonzales C, Ullrich ND, Gerber S, Berthonneche C, Niggli E, Pedrazzini T. Isolation of cardiovascular precursor cells from the human fetal heart. Tissue Engineering. Part A. 18: 198-207. PMID 21902604 DOI: 10.1089/Ten.Tea.2011.0022  0.308
2012 Gutierrez D, Ogrodnik J, Niggli E. Activation of Ca2+ Sparks during β-Adrenergic Stimulation in Resting Cardiomyocytes May Involve CAMKII and No, But Not ROS Biophysical Journal. 102: 98a. DOI: 10.1016/J.Bpj.2011.11.560  0.623
2012 Kyrychenko S, Poláková E, Ullrich ND, Niggli E, Shirokova N. Insights into RyRs Dysfunctions via Studies of Intracellular Calcium Signals Biophysical Journal. 102: 213a. DOI: 10.1016/J.Bpj.2011.11.1167  0.675
2011 Niggli E. Ryanodine receptors: waking up from refractoriness. Cardiovascular Research. 91: 563-4. PMID 21742677 DOI: 10.1093/Cvr/Cvr198  0.7
2011 Niggli E. Measuring calcium in 'fuzzy' spaces. The Journal of Physiology. 589: 2663. PMID 21632527 DOI: 10.1113/Jphysiol.2011.210336  0.695
2011 Ullrich ND, Fischer D, Kornblum C, Walter MC, Niggli E, Zorzato F, Treves S. Alterations of excitation-contraction coupling and excitation coupled Ca(2+) entry in human myotubes carrying CAV3 mutations linked to rippling muscle. Human Mutation. 32: 309-17. PMID 21294223 DOI: 10.1002/Humu.21431  0.572
2011 Kyrychenko S, Poláková E, Poscai K, Ullrich ND, Niggli E, Shirokova N. Hypersensitive Intracellular Ca2+ Signaling Precedes Deterioration of Cardiac Functions in Muscular Dystrophy Biophysical Journal. 100: 562a. DOI: 10.1016/J.Bpj.2010.12.3263  0.686
2011 Gutierrez D, Ogrodnik J, Niggli E. Activation of Calcium Sparks in Resting Cardiomyocytes by β-Adrenergic Stimulation May Involve CaMKII and nNOS Biophysical Journal. 100: 559a. DOI: 10.1016/J.Bpj.2010.12.3248  0.67
2011 Ullrich ND, Niggli E. Cardiac Ryanodine Receptor Phosphorylation at Ser2808 is Involved in Intra-SR Calcium Sensing Biophysical Journal. 100: 353a. DOI: 10.1016/J.Bpj.2010.12.2122  0.671
2010 Swift F, Tovsrud N, Sjaastad I, Sejersted OM, Niggli E, Egger M. Functional coupling of alpha(2)-isoform Na(+)/K(+)-ATPase and Ca(2+) extrusion through the Na(+)/Ca(2+)-exchanger in cardiomyocytes. Cell Calcium. 48: 54-60. PMID 20667414 DOI: 10.1016/J.Ceca.2010.06.006  0.554
2010 Niggli E. Ca2+ on the move: what is better - fire and forget, or fire-diffuse-fire? The Journal of Physiology. 588: 1391-2. PMID 20436043 DOI: 10.1113/Jphysiol.2010.190306  0.668
2010 Ogrodnik J, Niggli E. Increased Ca(2+) leak and spatiotemporal coherence of Ca(2+) release in cardiomyocytes during beta-adrenergic stimulation. The Journal of Physiology. 588: 225-42. PMID 19900959 DOI: 10.1113/Jphysiol.2009.181800  0.694
2010 Ullrich ND, Niggli E. Impaired Ca2+ Release Synchronization in RyR2-S2808a Mouse Cardiomyocytes During β-Adrenergic Stimulation Biophysical Journal. 98: 550a. DOI: 10.1016/J.Bpj.2009.12.2979  0.608
2010 Ogrodnik J, Gutierrez D, Niggli E. β-Adrenergic Stimulation and SR Ca2+ Leak in Cardiomyocytes Biophysical Journal. 98: 549a-550a. DOI: 10.1016/J.Bpj.2009.12.2978  0.687
2010 Fanchaouy M, Pocsai K, Shirokova N, Niggli E. Redox Modifications of Ca2+-Release Events in Cardiomyocytes Biophysical Journal. 98: 549a. DOI: 10.1016/J.Bpj.2009.12.2975  0.649
2009 Gusev K, Ackermann GE, Heizmann CW, Niggli E. Ca2+ signaling in mouse cardiomyocytes with ablated S100A1 protein. General Physiology and Biophysics. 28: 371-83. PMID 20097960 DOI: 10.4149/Gpb_2009_04_371  0.7
2009 Sztretye M, Almássy J, Deli T, Szentesi P, Jung C, Dienes B, Simut CA, Niggli E, Jona I, Csernoch L. Altered sarcoplasmic reticulum calcium transport in the presence of the heavy metal chelator TPEN. Cell Calcium. 46: 347-55. PMID 19900703 DOI: 10.1016/J.Ceca.2009.10.002  0.675
2009 Niggli E. How to shut down Ca2+-induced Ca2+ release? The Journal of Physiology. 587: 5003-4. PMID 19880872 DOI: 10.1113/Jphysiol.2009.181578  0.706
2009 Ullrich ND, Fanchaouy M, Gusev K, Shirokova N, Niggli E. Hypersensitivity of excitation-contraction coupling in dystrophic cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1992-2003. PMID 19783774 DOI: 10.1152/Ajpheart.00602.2009  0.636
2009 Fanchaouy M, Polakova E, Jung C, Ogrodnik J, Shirokova N, Niggli E. Pathways of abnormal stress-induced Ca2+ influx into dystrophic mdx cardiomyocytes. Cell Calcium. 46: 114-21. PMID 19604578 DOI: 10.1016/J.Ceca.2009.06.002  0.635
2009 Gusev K, Domenighetti AA, Delbridge LM, Pedrazzini T, Niggli E, Egger M. Angiotensin II-mediated adaptive and maladaptive remodeling of cardiomyocyte excitation-contraction coupling. Circulation Research. 105: 42-50. PMID 19478206 DOI: 10.1161/Circresaha.108.189779  0.613
2009 Shkryl VM, Martins AS, Ullrich ND, Nowycky MC, Niggli E, Shirokova N. Reciprocal amplification of ROS and Ca(2+) signals in stressed mdx dystrophic skeletal muscle fibers. Pflã¼Gers Archiv : European Journal of Physiology. 458: 915-28. PMID 19387681 DOI: 10.1007/S00424-009-0670-2  0.538
2009 Ullrich ND, Fanchaouy M, Gusev K, Polakova E, Shirokova N, Niggli E. Changes of EC-coupling and RyR Calcium Sensitivity in Dystrophic mdx Mouse Cardiomyocytes Biophysical Journal. 96: 10a-11a. DOI: 10.1016/J.Bpj.2008.12.951  0.691
2009 Ogrodnik J, Niggli E. Altered Ryanodine Receptor Sensitivity after ß-Adrenergic Stimulation of Guinea-pig Ventricular Myocytes Biophysical Journal. 96: 276a. DOI: 10.1016/J.Bpj.2008.12.1365  0.699
2008 Gusev K, Niggli E. Modulation of the local SR Ca2+ release by intracellular Mg2+ in cardiac myocytes. The Journal of General Physiology. 132: 721-30. PMID 19029377 DOI: 10.1085/Jgp.200810119  0.656
2008 Shirokova N, Niggli E. Studies of RyR function in situ. Methods (San Diego, Calif.). 46: 183-93. PMID 18848990 DOI: 10.1016/J.Ymeth.2008.09.017  0.601
2008 Jung C, Martins AS, Niggli E, Shirokova N. Dystrophic cardiomyopathy: amplification of cellular damage by Ca2+ signalling and reactive oxygen species-generating pathways. Cardiovascular Research. 77: 766-73. PMID 18056762 DOI: 10.1093/Cvr/Cvm089  0.594
2007 Keller M, Pignier C, Egger M, Niggli E. F90927: a new member in the class of cardioactive steroids. Cardiovascular Drug Reviews. 25: 210-20. PMID 17919256 DOI: 10.1111/J.1527-3466.2007.00014.X  0.53
2007 Niggli E, Shirokova N. A guide to sparkology: the taxonomy of elementary cellular Ca2+ signaling events. Cell Calcium. 42: 379-87. PMID 17428535 DOI: 10.1016/J.Ceca.2007.02.010  0.6
2007 Keller M, Kao JP, Egger M, Niggli E. Calcium waves driven by "sensitization" wave-fronts. Cardiovascular Research. 74: 39-45. PMID 17336953 DOI: 10.1016/J.Cardiores.2007.02.006  0.676
2007 Niggli E. The cardiac sarcoplasmic reticulum: filled with Ca2+ and surprises. Circulation Research. 100: 5-6. PMID 17204657 DOI: 10.1161/01.Res.0000255896.06757.97  0.7
2007 Jung C, Zima AV, Szentesi P, Jona I, Blatter LA, Niggli E. Ca2+ release from the sarcoplasmic reticulum activated by the low affinity Ca2+ chelator TPEN in ventricular myocytes. Cell Calcium. 41: 187-94. PMID 16920191 DOI: 10.1016/J.Ceca.2006.06.009  0.701
2006 Keller M, Pignier C, Santelli M, Vacher B, Niggli E, Egger M. Agonist specific L-type Ca(2+)-current stimulation in ventricular myocytes by a novel steroid-like compound. Cell Calcium. 39: 425-33. PMID 16540165 DOI: 10.1016/J.Ceca.2006.01.006  0.632
2006 Pignier C, Keller M, Vié B, Vacher B, Santelli M, Niggli E, Egger M, Le Grand B. A novel steroid-like compound F90927 exerting positive-inotropic effects in cardiac muscle. British Journal of Pharmacology. 147: 772-82. PMID 16474419 DOI: 10.1038/Sj.Bjp.0706673  0.347
2006 Momotake A, Lindegger N, Niggli E, Barsotti RJ, Ellis-Davies GC. The nitrodibenzofuran chromophore: a new caging group for ultra-efficient photolysis in living cells. Nature Methods. 3: 35-40. PMID 16369551 DOI: 10.1038/Nmeth821  0.586
2006 Niggli E, Kléber A, Weingart R. Founder of cardiac cellular electrophysiology: honouring Silvio Weidmann, 7 April 1921- 11 July 2005. The Journal of Physiology. 570: 431-2. PMID 16322050 DOI: 10.1113/Jphysiol.2005.101550  0.352
2006 Kantevari S, Hoang CJ, Ogrodnik J, Egger M, Niggli E, Ellis-Davies GC. Synthesis and two-photon photolysis of 6-(ortho-nitroveratryl)-caged IP3 in living cells. Chembiochem : a European Journal of Chemical Biology. 7: 174-80. PMID 16292788 DOI: 10.1002/Cbic.200500345  0.382
2005 Shannon TR, Bers DM, Blatter LA, Niggli E. Confocal imaging of CICR events from isolated and immobilized SR vesicles. Cell Calcium. 38: 497-505. PMID 16122794 DOI: 10.1016/J.Ceca.2005.07.002  0.677
2005 Lindegger N, Niggli E. Paradoxical SR Ca2+ release in guinea-pig cardiac myocytes after beta-adrenergic stimulation revealed by two-photon photolysis of caged Ca2+. The Journal of Physiology. 565: 801-13. PMID 15774509 DOI: 10.1113/Jphysiol.2005.084376  0.69
2005 Egger M, Porzig H, Niggli E, Schwaller B. Rapid turnover of the "functional" Na(+)-Ca2+ exchanger in cardiac myocytes revealed by an antisense oligodeoxynucleotide approach. Cell Calcium. 37: 233-43. PMID 15670870 DOI: 10.1016/J.Ceca.2004.10.006  0.506
2004 Szentesi P, Pignier C, Egger M, Kranias EG, Niggli E. Sarcoplasmic reticulum Ca2+ refilling controls recovery from Ca2+-induced Ca2+ release refractoriness in heart muscle. Circulation Research. 95: 807-13. PMID 15388639 DOI: 10.1161/01.Res.0000146029.80463.7D  0.701
2004 Keller M, Pignier C, Niggli E, Egger M. Mechanisms of Na+-Ca2+ exchange inhibition by amphiphiles in cardiac myocytes: importance of transbilayer movement. The Journal of Membrane Biology. 198: 159-75. PMID 15216417 DOI: 10.1007/S00232-004-0668-9  0.607
2002 Michailova A, DelPrincipe F, Egger M, Niggli E. Spatiotemporal features of Ca2+ buffering and diffusion in atrial cardiac myocytes with inhibited sarcoplasmic reticulum. Biophysical Journal. 83: 3134-51. PMID 12496084 DOI: 10.1016/S0006-3495(02)75317-4  0.686
2002 Darbon P, Pignier C, Niggli E, Streit J. Involvement of calcium in rhythmic activity induced by disinhibition in cultured spinal cord networks. Journal of Neurophysiology. 88: 1461-8. PMID 12205166 DOI: 10.1152/Jn.2002.88.3.1461  0.372
2002 Gómez AM, Schwaller B, Porzig H, Vassort G, Niggli E, Egger M. Increased exchange current but normal Ca2+ transport via Na+-Ca2+ exchange during cardiac hypertrophy after myocardial infarction. Circulation Research. 91: 323-30. PMID 12193465 DOI: 10.1161/01.Res.0000031384.55006.Db  0.68
2002 Lipp P, Egger M, Niggli E. Spatial characteristics of sarcoplasmic reticulum Ca2+ release events triggered by L-type Ca2+ current and Na+ current in guinea-pig cardiac myocytes. The Journal of Physiology. 542: 383-93. PMID 12122139 DOI: 10.1113/Jphysiol.2001.013382  0.693
2002 Niggli E, Egger M. Calcium quarks. Frontiers in Bioscience : a Journal and Virtual Library. 7: d1288-97. PMID 11991844  0.569
2000 DelPrincipe F, Egger M, Niggli E. L-type Ca2+ current as the predominant pathway of Ca2+ entry during I(Na) activation in beta-stimulated cardiac myocytes. The Journal of Physiology. 527: 455-66. PMID 10990533 DOI: 10.1111/J.1469-7793.2000.00455.X  0.679
2000 Egger M, Niggli E. Paradoxical block of the Na+-Ca2+ exchanger by extracellular protons in guinea-pig ventricular myocytes. The Journal of Physiology. 523: 353-66. PMID 10699080 DOI: 10.1111/J.1469-7793.2000.T01-1-00353.X  0.678
2000 Schwaller B, Egger M, Lipp P, Niggli E. Application of antisense oligodeoxynucleotides for suppression of Na+/Ca2+ exchange. Methods in Enzymology. 314: 454-76. PMID 10565032 DOI: 10.1016/S0076-6879(99)14122-3  0.645
1999 Niggli E. Ca(2+) Sparks in Cardiac Muscle: Is There Life Without Them? News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 14: 129-134. PMID 11390838 DOI: 10.1152/Physiologyonline.1999.14.4.129  0.634
1999 DelPrincipe F, Egger M, Niggli E. Calcium signalling in cardiac muscle: refractoriness revealed by coherent activation. Nature Cell Biology. 1: 323-9. PMID 10559957 DOI: 10.1038/14013  0.699
1999 Egger M, Ruknudin A, Niggli E, Lederer WJ, Schulze DH. Ni2+ transport by the human Na+/Ca2+ exchanger expressed in Sf9 cells. The American Journal of Physiology. 276: C1184-92. PMID 10329968 DOI: 10.1152/Ajpcell.1999.276.5.C1184  0.592
1999 DelPrincipe F, Egger M, Ellis-Davies GC, Niggli E. Two-photon and UV-laser flash photolysis of the Ca2+ cage, dimethoxynitrophenyl-EGTA-4. Cell Calcium. 25: 85-91. PMID 10191963 DOI: 10.1054/Ceca.1998.0009  0.628
1999 Egger M, Ruknudin A, Lipp P, Kofuji P, Lederer WJ, Schulze DH, Niggli E. Functional expression of the human cardiac Na+/Ca2+ exchanger in Sf9 cells: rapid and specific Ni2+ transport. Cell Calcium. 25: 9-17. PMID 10191956 DOI: 10.1054/Ceca.1998.0002  0.658
1999 Niggli E. Localized intracellular calcium signaling in muscle: calcium sparks and calcium quarks. Annual Review of Physiology. 61: 311-35. PMID 10099691 DOI: 10.1146/Annurev.Physiol.61.1.311  0.694
1999 Egger M, Niggli E. Regulatory function of Na-Ca exchange in the heart: milestones and outlook. The Journal of Membrane Biology. 168: 107-30. PMID 10089232 DOI: 10.1007/S002329900502  0.593
1999 Assandri R, Egger M, Gassmann M, Niggli E, Bauer C, Forster I, Gorlach A. Erythropoietin modulates intracellular calcium in a human neuroblastoma cell line. The Journal of Physiology. 516: 343-52. PMID 10087335 DOI: 10.1111/J.1469-7793.1999.0343V.X  0.615
1998 Blatter LA, Niggli E. Confocal near-membrane detection of calcium in cardiac myocytes. Cell Calcium. 23: 269-79. PMID 9681190 DOI: 10.1016/S0143-4160(98)90023-9  0.658
1998 Lipp P, Niggli E. Fundamental calcium release events revealed by two-photon excitation photolysis of caged calcium in Guinea-pig cardiac myocytes. The Journal of Physiology. 508: 801-9. PMID 9518734 DOI: 10.1111/J.1469-7793.1998.801Bp.X  0.703
1997 Bootman M, Niggli E, Berridge M, Lipp P. Imaging the hierarchical Ca2+ signalling system in HeLa cells. The Journal of Physiology. 499: 307-14. PMID 9080361 DOI: 10.1113/Jphysiol.1997.Sp021928  0.684
1996 Lipp P, Niggli E. A hierarchical concept of cellular and subcellular Ca(2+)-signalling. Progress in Biophysics and Molecular Biology. 65: 265-96. PMID 9062435 DOI: 10.1016/S0079-6107(96)00014-4  0.615
1996 Lipp P, Hüser J, Pott L, Niggli E. Subcellular properties of triggered Ca2+ waves in isolated citrate-loaded guinea-pig atrial myocytes characterized by ratiometric confocal microscopy. The Journal of Physiology. 497: 599-610. PMID 9003547 DOI: 10.1113/Jphysiol.1996.Sp021793  0.694
1996 Lipp P, Hüser J, Pott L, Niggli E. Spatially non-uniform Ca2+ signals induced by the reduction of transverse tubules in citrate-loaded guinea-pig ventricular myocytes in culture. The Journal of Physiology. 497: 589-97. PMID 9003546 DOI: 10.1113/Jphysiol.1996.Sp021792  0.682
1996 Lüscher C, Lipp P, Lüscher HR, Niggli E. Control of action potential propagation by intracellular Ca2+ in cultured rat dorsal root ganglion cells. The Journal of Physiology. 490: 319-24. PMID 8821131 DOI: 10.1113/Jphysiol.1996.Sp021146  0.642
1996 Lipp P, Lüscher C, Niggli E. Photolysis of caged compounds characterized by ratiometric confocal microscopy: a new approach to homogeneously control and measure the calcium concentration in cardiac myocytes. Cell Calcium. 19: 255-66. PMID 8732265 DOI: 10.1016/S0143-4160(96)90026-3  0.691
1996 Lipp P, Niggli E. Submicroscopic calcium signals as fundamental events of excitation--contraction coupling in guinea-pig cardiac myocytes. The Journal of Physiology. 492: 31-8. PMID 8730580 DOI: 10.1113/Jphysiol.1996.Sp021286  0.701
1996 Niggli E, Schwaller B, Lipp P. Antisense oligodeoxynucleotides directed against the Na-Ca exchanger mRNA. Promising tools for studies on the cellular and molecular level. Annals of the New York Academy of Sciences. 779: 93-102. PMID 8659885 DOI: 10.1111/J.1749-6632.1996.Tb44773.X  0.524
1995 Trafford AW, Lipp P, O'Neill SC, Niggli E, Eisner DA. Propagating calcium waves initiated by local caffeine application in rat ventricular myocytes. The Journal of Physiology. 489: 319-26. PMID 8847628 DOI: 10.1113/Jphysiol.1995.Sp021053  0.638
1995 Lipp P, Schwaller B, Niggli E. Specific inhibition of Na-Ca exchange function by antisense oligodeoxynucleotides. Febs Letters. 364: 198-202. PMID 7750570 DOI: 10.1016/0014-5793(95)00391-L  0.677
1994 Niggli E, Piston DW, Kirby MS, Cheng H, Sandison DR, Webb WW, Lederer WJ. A confocal laser scanning microscope designed for indicators with ultraviolet excitation wavelengths. The American Journal of Physiology. 266: C303-10. PMID 8304426 DOI: 10.1152/Ajpcell.1994.266.1.C303  0.398
1994 Lipp P, Niggli E. Modulation of Ca2+ release in cultured neonatal rat cardiac myocytes. Insight from subcellular release patterns revealed by confocal microscopy. Circulation Research. 74: 979-90. PMID 8156645 DOI: 10.1161/01.Res.74.5.979  0.658
1994 Lipp P, Niggli E. Sodium current-induced calcium signals in isolated guinea-pig ventricular myocytes. The Journal of Physiology. 474: 439-46. PMID 8014905 DOI: 10.1113/Jphysiol.1994.Sp020035  0.701
1994 Niggli E, Lipp P. Voltage dependence of Na-Ca exchanger conformational currents. Biophysical Journal. 67: 1516-24. PMID 7819485 DOI: 10.1016/S0006-3495(94)80625-3  0.633
1993 Lipp P, Niggli E. Ratiometric confocal Ca(2+)-measurements with visible wavelength indicators in isolated cardiac myocytes. Cell Calcium. 14: 359-72. PMID 8519060 DOI: 10.1016/0143-4160(93)90040-D  0.618
1993 Lipp P, Niggli E. Microscopic spiral waves reveal positive feedback in subcellular calcium signaling. Biophysical Journal. 65: 2272-6. PMID 8312468 DOI: 10.1016/S0006-3495(93)81316-X  0.656
1993 Schulze D, Kofuji P, Hadley R, Kirby MS, Kieval RS, Doering A, Niggli E, Lederer WJ. Sodium/calcium exchanger in heart muscle: molecular biology, cellular function, and its special role in excitation-contraction coupling. Cardiovascular Research. 27: 1726-34. PMID 8275517 DOI: 10.1093/Cvr/27.10.1726  0.6
1993 Niggli E, Lederer WJ. Activation of Na-Ca exchange current by photolysis of "caged calcium". Biophysical Journal. 65: 882-91. PMID 8218911 DOI: 10.1016/S0006-3495(93)81105-6  0.657
1991 Niggli E, Lederer WJ. Molecular operations of the sodium-calcium exchanger revealed by conformation currents. Nature. 349: 621-4. PMID 2000135 DOI: 10.1038/349621A0  0.553
1991 Niggli E, Lederer WJ. Restoring forces in cardiac myocytes. Insight from relaxations induced by photolysis of caged ATP. Biophysical Journal. 59: 1123-35. PMID 1868157 DOI: 10.1016/S0006-3495(91)82327-X  0.374
1991 Niggli E, Lederer WJ. Photorelease of Ca2+ produces Na-Ca exchange currents and Na-Ca exchange "gating" currents. Annals of the New York Academy of Sciences. 639: 61-70. PMID 1785890 DOI: 10.1111/J.1749-6632.1991.Tb17289.X  0.644
1990 Niggli E, Lederer WJ. Real-time confocal microscopy and calcium measurements in heart muscle cells: towards the development of a fluorescence microscope with high temporal and spatial resolution. Cell Calcium. 11: 121-30. PMID 2354496 DOI: 10.1016/0143-4160(90)90065-3  0.328
1990 Lederer WJ, Niggli E, Hadley RW. Sodium-calcium exchange in excitable cells: fuzzy space. Science (New York, N.Y.). 248: 283. PMID 2326638 DOI: 10.1126/Science.2326638  0.407
1990 Niggli E, Lederer WJ. Voltage-independent calcium release in heart muscle. Science (New York, N.Y.). 250: 565-8. PMID 2173135 DOI: 10.1126/Science.2173135  0.604
1989 Niggli E. Strontium-induced creep currents associated with tonic contractions in cardiac myocytes isolated from guinea-pigs. The Journal of Physiology. 414: 549-68. PMID 2607441 DOI: 10.1113/Jphysiol.1989.Sp017703  0.569
1989 Niggli E, Rüdisüli A, Maurer P, Weingart R. Effects of general anesthetics on current flow across membranes in guinea pig myocytes. The American Journal of Physiology. 256: C273-81. PMID 2537569 DOI: 10.1152/Ajpcell.1989.256.2.C273  0.351
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