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Guoxia Han, Ph.D. - Publications

Affiliations: 
2000 University of Arizona, Tucson, AZ 
Area:
Organic Chemistry, Biochemistry, Chemical Biology and Medicinal Chemistry
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Miller RL, Thompson AA, Trapella C, Guerrini R, Malfacini D, Patel N, Han GW, Cherezov V, Caló G, Katritch V, Stevens RC. The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor. Structure (London, England : 1993). PMID 26526853 DOI: 10.1016/J.Str.2015.07.024  0.315
2015 Zhang H, Unal H, Desnoyer R, Han GW, Patel N, Katritch V, Karnik SS, Cherezov V, Stevens RC. Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor. The Journal of Biological Chemistry. PMID 26420482 DOI: 10.1074/Jbc.M115.689000  0.329
2010 Han G, Lewis A, Hruby VJ. ChemInform Abstract: Synthesis of (2S,3S)-β-Methyltryptophan. Cheminform. 32: no-no. DOI: 10.1002/chin.200140197  0.302
2010 Tamaki M, Han G, Hruby VJ. ChemInform Abstract: Synthesis of 4-cis-Phenyl-L-proline via Hydrogenolysis. Cheminform. 32: no-no. DOI: 10.1002/chin.200138179  0.301
2007 Grieco P, Cai M, Han G, Trivedi D, Campiglia P, Novellino E, Hruby VJ. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides. 28: 1191-6. PMID 17482720 DOI: 10.1016/J.Peptides.2007.02.012  0.668
2005 Hsu R, Taylor JR, Newton SS, Alvaro JD, Haile C, Han G, Hruby VJ, Nestler EJ, Duman RS. Blockade of melanocortin transmission inhibits cocaine reward. The European Journal of Neuroscience. 21: 2233-42. PMID 15869520 DOI: 10.1111/J.1460-9568.2005.04038.X  0.384
2004 Han G, Haskell-Luevano C, Kendall L, Bonner G, Hadley ME, Cone RD, Hruby VJ. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach. Journal of Medicinal Chemistry. 47: 1514-26. PMID 14998337 DOI: 10.1021/Jm030452X  0.634
2003 Ying J, Kövér KE, Gu X, Han G, Trivedi DB, Kavarana MJ, Hruby VJ. Solution structures of cyclic melanocortin agonists and antagonists by NMR. Biopolymers. 71: 696-716. PMID 14991679 DOI: 10.1002/Bip.10596  0.687
2003 Grieco P, Balse-Srinivasan P, Han G, Weinberg D, MacNeil T, Van der Ploeg LH, Hruby VJ. Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. The Journal of Peptide Research : Official Journal of the American Peptide Society. 62: 199-206. PMID 14531843 DOI: 10.1034/J.1399-3011.2003.00087.X  0.579
2003 Wessells H, Hruby VJ, Hackett J, Han G, Balse-Srinivasan P, Vanderah TW. MT-II induces penile erection via brain and spinal mechanisms. Annals of the New York Academy of Sciences. 994: 90-5. PMID 12851302 DOI: 10.1111/J.1749-6632.2003.Tb03166.X  0.446
2003 Hruby VJ, Cai M, Grieco P, Han G, Kavarana M, Trivedi D. Exploring the stereostructural requirements of peptide ligands for the melanocortin receptors. Annals of the New York Academy of Sciences. 994: 12-20. PMID 12851293 DOI: 10.1111/J.1749-6632.2003.Tb03157.X  0.645
2003 Wessells H, Hruby VJ, Hackett J, Han G, Balse-Srinivasan P, Vanderah TW. Ac-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-NH2 induces penile erection via brain and spinal melanocortin receptors. Neuroscience. 118: 755-62. PMID 12710982 DOI: 10.1016/S0306-4522(02)00866-7  0.448
2003 Han G, Quillan JM, Carlson K, Sadée W, Hruby VJ. Design of novel chimeric melanotropin-deltorphin analogues. Discovery of the first potent human melanocortin 1 receptor antagonist. Journal of Medicinal Chemistry. 46: 810-9. PMID 12593660 DOI: 10.1021/Jm020355O  0.582
2002 Kavarana MJ, Trivedi D, Cai M, Ying J, Hammer M, Cabello C, Grieco P, Han G, Hruby VJ. Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors. Journal of Medicinal Chemistry. 45: 2644-50. PMID 12036373 DOI: 10.1021/Jm020021Z  0.705
2002 Grieco P, Balse-Srinivasan P, Han G, Weinberg D, MacNeil T, Van der Ploeg LH, Hruby VJ. Synthesis and biological evaluation on hMC3, hMC4 and hMC5 receptors of gamma-MSH analogs substituted with L-alanine. The Journal of Peptide Research : Official Journal of the American Peptide Society. 59: 203-10. PMID 11966977 DOI: 10.1034/J.1399-3011.2002.01966.X  0.499
2002 Grieco P, Han G, Weinberg D, Van der Ploeg LH, Hruby VJ. Design and synthesis of highly potent and selective melanotropin analogues of SHU9119 modified at position 6. Biochemical and Biophysical Research Communications. 292: 1075-80. PMID 11944925 DOI: 10.1006/Bbrc.2002.6739  0.581
2001 Han G, Tamaki M, Hruby VJ. Fast, efficient and selective deprotection of the tert-butoxycarbonyl (Boc) group using HCl/dioxane (4 m). The Journal of Peptide Research : Official Journal of the American Peptide Society. 58: 338-41. PMID 11606219 DOI: 10.1034/J.1399-3011.2001.00935.X  0.45
2001 Tamaki M, Han G, Hruby VJ. Practical and efficient synthesis of orthogonally protected constrained 4-guanidinoprolines. The Journal of Organic Chemistry. 66: 1038-42. PMID 11430070 DOI: 10.1021/Jo005626M  0.377
2001 Tamaki M, Han G, Hruby VJ. Synthesis of 4-cis-phenyl-L-proline via hydrogenolysis. The Journal of Organic Chemistry. 66: 3593-6. PMID 11348150 DOI: 10.1021/Jo005625U  0.379
2001 Han G, Hruby VJ. A study of conjugate addition to a γ,δ-dioxolanyl-α,β-unsaturated ester Tetrahedron Letters. 42: 4281-4283. DOI: 10.1016/S0040-4039(01)00719-5  0.397
2001 Han G, Lewis A, Hruby VJ. Synthesis of (2S,3S)-β-methyltryptophan Tetrahedron Letters. 42: 4601-4603. DOI: 10.1016/S0040-4039(01)00718-3  0.402
2000 Balse PM, Kim HJ, Han G, Hruby VJ. Evaluation of new base-labile 2-(4-nitrophenylsulfonyl) ethoxycarbonyl (Nsc)-amino acids for solid-phase peptide synthesis. The Journal of Peptide Research : Official Journal of the American Peptide Society. 56: 70-9. PMID 10961541 DOI: 10.1034/J.1399-3011.2000.00759.X  0.475
2000 Hohmann JG, Teal TH, Clifton DK, Davis J, Hruby VJ, Han G, Steiner RA. Differential role of melanocortins in mediating leptin's central effects on feeding and reproduction. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R50-9. PMID 10644621 DOI: 10.1152/Ajpregu.2000.278.1.R50  0.412
1999 Han G, Hampson DR. Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor. The Journal of Biological Chemistry. 274: 10008-13. PMID 10187777 DOI: 10.1074/jbc.274.15.10008  0.313
1998 Hruby VJ, Han G, Hadley ME. Letters in Peptide Science. 5: 117-120. DOI: 10.1023/A:1008808525647  0.325
1998 Hruby VJ, Han G, Hadley ME. Design and bioactivities of melanotropic peptide agonists and antagonists: Design based on a conformationally constrained somatostatin template Letters in Peptide Science. 5: 117-120. DOI: 10.1007/Bf02443451  0.564
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