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Andrew P. VanDemark, Ph.D. - Publications

Affiliations: 
2002 Johns Hopkins University, Baltimore, MD 
Area:
lysine ubiquitination and acetylation, using x-ray crystallography, together with biochemical, biophysical and genetic analysis
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 VanDemark AP, Hrizo SL, Eicher SL, Kowalski J, Myers TD, Pfeifer MR, Riley KN, Koeberl DD, Palladino MJ. Itavastatin and Resveratrol increase triosephosphate isomerase protein (TPI) in a newly identified variant, TPIQ181P, that confers TPI deficiency. Disease Models & Mechanisms. PMID 35315486 DOI: 10.1242/dmm.049261  0.345
2020 Googins MR, Woghiren-Afegbua AO, Calderon M, St Croix CM, Kiselyov KI, VanDemark AP. Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32274853 DOI: 10.1096/Fj.202000110R  0.462
2019 Rosenbaum JC, Bonilla B, Hengel SR, Mertz TM, Herken BW, Kazemier HG, Pressimone CA, Ratterman TC, MacNary E, De Magis A, Kwon Y, Godin SK, Van Houten B, Normolle DP, Sung P, ... ... VanDemark AP, et al. The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway. Nature Communications. 10: 3515. PMID 31383866 DOI: 10.1038/S41467-019-11374-8  0.356
2019 Roland BP, Richards KR, Hrizo SL, Eicher S, Barile ZJ, Chang TC, Savon G, Bianchi P, Fermo E, Ricerca BM, Tortorolo L, Vockley J, VanDemark AP, Palladino MJ. Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 31075491 DOI: 10.1016/J.Bbadis.2019.05.002  0.719
2019 Mikulska-Ruminska K, Shrivastava IH, Krieger J, Zhang S, Li H, Bayir H, Wenzel SE, VanDemark AP, Kagan VE, Bahar I. Characterization of differential dynamics, specificity, and allostery of lipoxygenase family members. Journal of Chemical Information and Modeling. PMID 30762363 DOI: 10.1021/Acs.Jcim.9B00006  0.34
2018 Anthonymuthu TS, Kenny EM, Shrivastava IH, Tyurina YY, Hier ZE, Ting HC, Dar H, Tyurin VA, Nesterova A, Amoscato AA, Mikulska-Ruminska K, Rosenbaum JC, Mao G, Jinming Z, Conrad M, ... ... VanDemark AP, et al. Empowerment of 15-lipoxygenase catalytic competence in selective oxidation of membrane ETE-PE to ferroptotic death signals, HpETE-PE. Journal of the American Chemical Society. PMID 30525572 DOI: 10.1021/Jacs.8B09913  0.311
2017 Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, ... ... VanDemark AP, et al. PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals. Cell. 171: 628-641.e26. PMID 29053969 DOI: 10.1016/J.Cell.2017.09.044  0.323
2017 Zalewski JK, Heber S, Mo JH, O'Conor K, Hildebrand JD, VanDemark AP. Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins. Journal of Visualized Experiments : Jove. PMID 28117766 DOI: 10.3791/54886  0.332
2016 Van Oss SB, Shirra MK, Bataille AR, Wier AD, Yen K, Vinayachandran V, Byeon IL, Cucinotta CE, Héroux A, Jeon J, Kim J, VanDemark AP, Pugh BF, Arndt KM. The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6. Molecular Cell. PMID 27840029 DOI: 10.1016/J.Molcel.2016.10.008  0.377
2016 Zalewski JK, Mo JH, Heber S, Heroux A, Gardner RG, Hildebrand JD, VanDemark AP. Structure of the Shroom-Rho kinase complex reveals a binding interface with monomeric Shroom that regulates cell morphology and stimulates kinase activity. The Journal of Biological Chemistry. PMID 27758857 DOI: 10.1074/Jbc.M116.738559  0.403
2016 Roland BP, Zeccola AM, Larsen SB, Amrich CG, Talsma AD, Stuchul KA, Heroux A, Levitan ES, VanDemark AP, Palladino MJ. Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics. Plos Genetics. 12: e1005941. PMID 27031109 DOI: 10.1371/Journal.Pgen.1005941  0.702
2015 Gaines WA, Godin SK, Kabbinavar FF, Rao T, VanDemark AP, Sung P, Bernstein KA. Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52. Nature Communications. 6: 7834. PMID 26215801 DOI: 10.1038/Ncomms8834  0.332
2015 Roland BP, Amrich CG, Kammerer CJ, Stuchul KA, Larsen SB, Rode S, Aslam AA, Heroux A, Wetzel R, VanDemark AP, Palladino MJ. Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency. Biochimica Et Biophysica Acta. 1852: 61-9. PMID 25463631 DOI: 10.1016/J.Bbadis.2014.10.010  0.73
2014 Das D, Zalewski JK, Mohan S, Plageman TF, VanDemark AP, Hildebrand JD. The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice. Biology Open. 3: 850-60. PMID 25171888 DOI: 10.1242/Bio.20147450  0.354
2014 Singh S, Rockenbach K, Dedrick RM, VanDemark AP, Hatfull GF. Cross-talk between diverse serine integrases. Journal of Molecular Biology. 426: 318-31. PMID 24161951 DOI: 10.1016/J.Jmb.2013.10.013  0.31
2014 Singh S, Plaks JG, Homa NJ, Amrich CG, Héroux A, Hatfull GF, VanDemark AP. The structure of Xis reveals the basis for filament formation and insight into DNA bending within a mycobacteriophage intasome. Journal of Molecular Biology. 426: 412-22. PMID 24112940 DOI: 10.1016/J.Jmb.2013.10.002  0.335
2013 Mohan S, Das D, Bauer RJ, Heroux A, Zalewski JK, Heber S, Dosunmu-Ogunbi AM, Trakselis MA, Hildebrand JD, Vandemark AP. Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology. Plos One. 8: e81075. PMID 24349032 DOI: 10.1371/Journal.Pone.0081075  0.413
2013 Wier AD, Mayekar MK, Héroux A, Arndt KM, VanDemark AP. Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proceedings of the National Academy of Sciences of the United States of America. 110: 17290-5. PMID 24101474 DOI: 10.1073/Pnas.1314754110  0.398
2013 Roland BP, Stuchul KA, Larsen SB, Amrich CG, Vandemark AP, Celotto AM, Palladino MJ. Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity. Journal of Cell Science. 126: 3151-8. PMID 23641070 DOI: 10.1242/Jcs.124586  0.708
2013 Godin S, Wier A, Kabbinavar F, Bratton-Palmer DS, Ghodke H, Van Houten B, VanDemark AP, Bernstein KA. The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination. Nucleic Acids Research. 41: 4525-34. PMID 23460207 DOI: 10.1093/Nar/Gkt138  0.337
2012 Celotto AM, Liu Z, Vandemark AP, Palladino MJ. A novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and disease. Brain and Behavior. 2: 424-34. PMID 22950046 DOI: 10.1002/Brb3.73  0.351
2012 Mohan S, Rizaldy R, Das D, Bauer RJ, Heroux A, Trakselis MA, Hildebrand JD, VanDemark AP. Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction. Molecular Biology of the Cell. 23: 2131-42. PMID 22493320 DOI: 10.1091/Mbc.E11-11-0937  0.402
2012 Amrich CG, Davis CP, Rogal WP, Shirra MK, Heroux A, Gardner RG, Arndt KM, VanDemark AP. Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin. The Journal of Biological Chemistry. 287: 10863-75. PMID 22318720 DOI: 10.1074/Jbc.M111.325647  0.408
2010 D'Aiuto L, Marzulli M, Mohan KN, Borowczyk E, Saporiti F, Vandemark A, Chaillet JR. Dissection of structure and function of the N-terminal domain of mouse DNMT1 using regional frame-shift mutagenesis. Plos One. 5: e9831. PMID 20352123 DOI: 10.1371/Journal.Pone.0009831  0.366
2008 VanDemark AP, Xin H, McCullough L, Rawlins R, Bentley S, Heroux A, Stillman DJ, Hill CP, Formosa T. Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits. The Journal of Biological Chemistry. 283: 5058-68. PMID 18089575 DOI: 10.1074/Jbc.M708682200  0.436
2007 VanDemark AP, Kasten MM, Ferris E, Heroux A, Hill CP, Cairns BR. Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Molecular Cell. 27: 817-28. PMID 17803945 DOI: 10.1016/J.Molcel.2007.08.018  0.332
2007 VanDemark AP, Blanksma M, Ferris E, Heroux A, Hill CP, Formosa T. The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition (DOI:10.1016/j.molcel.2006.03.025) Molecular Cell. 27: 171-172. DOI: 10.1016/J.Molcel.2007.06.007  0.316
2006 VanDemark AP, Blanksma M, Ferris E, Heroux A, Hill CP, Formosa T. The structure of the yFACT Pob3-M domain, its interaction with the DNA replication factor RPA, and a potential role in nucleosome deposition. Molecular Cell. 22: 363-74. PMID 16678108 DOI: 10.1016/J.Molcel.2006.03.025  0.418
2005 Macbeth MR, Schubert HL, Vandemark AP, Lingam AT, Hill CP, Bass BL. Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing. Science (New York, N.Y.). 309: 1534-9. PMID 16141067 DOI: 10.1126/Science.1113150  0.389
2005 VanDemark AP, Hill CP. E1 on the move. Molecular Cell. 17: 474-5. PMID 15721250 DOI: 10.1016/J.Molcel.2005.02.004  0.309
2004 VanDemark AP, Hill CP. Grabbing E2 by the tail. Nature Structural & Molecular Biology. 11: 908-9. PMID 15452557 DOI: 10.1038/Nsmb1004-908  0.401
2003 VanDemark AP, Hill CP. Two-stepping with E1. Nature Structural Biology. 10: 244-6. PMID 12660720 DOI: 10.1038/Nsb0403-244  0.371
2002 VanDemark AP, Hill CP. Structural basis of ubiquitylation. Current Opinion in Structural Biology. 12: 822-30. PMID 12504688 DOI: 10.1016/S0959-440X(02)00389-5  0.396
2002 VanDemark AP, Hill CP. SUMO wrestling with specificity. Structure (London, England : 1993). 10: 281-2. PMID 12005425 DOI: 10.1016/S0969-2126(02)00727-X  0.385
2001 VanDemark AP, Hofmann RM, Tsui C, Pickart CM, Wolberger C. Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer. Cell. 105: 711-20. PMID 11440714 DOI: 10.1016/S0092-8674(01)00387-7  0.599
2000 Pickart CM, VanDemark AP. Opening doors into the proteasome Nature Structural Biology. 7: 999-1001. PMID 11062549 DOI: 10.1038/81018  0.32
2000 Jabet C, Sprague ER, VanDemark AP, Wolberger C. Characterization of the N-terminal domain of the yeast transcriptional repressor Tup1. Proposal for an association model of the repressor complex Tup1 x Ssn6. The Journal of Biological Chemistry. 275: 9011-8. PMID 10722750 DOI: 10.1074/Jbc.275.12.9011  0.676
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