| Year |
Citation |
Score |
| 2021 |
Amalina I, Bennett A, Whalley H, Perera D, McGrail JC, Tighe A, Procter DJ, Taylor SS. Inhibitors of the Bub1 spindle assembly checkpoint kinase: synthesis of BAY-320 and comparison with 2OH-BNPP1. Royal Society Open Science. 8: 210854. PMID 34925867 DOI: 10.1098/rsos.210854 |
0.326 |
|
| 2020 |
Todd S, Todd P, McGowan SJ, Hughes JR, Kakui Y, Fol Leymarie F, Latham W, Taylor S. CSynth: An Interactive Modelling and Visualisation Tool for 3D Chromatin Structure. Bioinformatics (Oxford, England). PMID 32866221 DOI: 10.1093/Bioinformatics/Btaa757 |
0.321 |
|
| 2020 |
Nelson L, Tighe A, Golder A, Littler S, Bakker B, Moralli D, Murtuza Baker S, Donaldson IJ, Spierings DCJ, Wardenaar R, Neale B, Burghel GJ, Winter-Roach B, Edmondson R, Clamp AR, ... ... Taylor SS, et al. A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity. Nature Communications. 11: 822. PMID 32054838 DOI: 10.1038/S41467-020-14551-2 |
0.362 |
|
| 2019 |
Littler S, Sloss O, Geary B, Pierce A, Whetton AD, Taylor SS. Oncogenic MYC amplifies mitotic perturbations. Open Biology. 9: 190136. PMID 31455158 DOI: 10.1098/Rsob.190136 |
0.454 |
|
| 2019 |
Pillay N, Tighe A, Nelson L, Littler S, Coulson-Gilmer C, Bah N, Golder A, Bakker B, Spierings DCJ, James DI, Smith KM, Jordan AM, Morgan RD, Ogilvie DJ, Foijer F, ... ... Taylor SS, et al. DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors. Cancer Cell. 35: 519-533.e8. PMID 30889383 DOI: 10.1016/J.Ccell.2019.02.004 |
0.334 |
|
| 2018 |
Simões-Sousa S, Littler S, Thompson SL, Minshall P, Whalley H, Bakker B, Belkot K, Moralli D, Bronder D, Tighe A, Spierings DCJ, Bah N, Graham J, Nelson L, Green CM, ... ... Taylor SS, et al. The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α. Cell Reports. 25: 749-760.e6. PMID 30332653 DOI: 10.1016/J.Celrep.2018.09.060 |
0.385 |
|
| 2017 |
Sloss O, Topham C, Diez M, Taylor S. Mcl-1 dynamics influence mitotic slippage and death in mitosis. Oncotarget. 7: 5176-92. PMID 26769847 DOI: 10.18632/oncotarget.6894 |
0.328 |
|
| 2016 |
Bennett A, Sloss O, Topham C, Nelson L, Tighe A, Taylor SS. Inhibition of Bcl-xL sensitizes cells to mitotic blockers, but not mitotic drivers. Open Biology. 6. PMID 27512141 DOI: 10.1098/Rsob.160134 |
0.435 |
|
| 2015 |
Davies JO, Telenius JM, McGowan SJ, Roberts NA, Taylor S, Higgs DR, Hughes JR. Multiplexed analysis of chromosome conformation at vastly improved sensitivity. Nature Methods. PMID 26595209 DOI: 10.1038/Nmeth.3664 |
0.329 |
|
| 2015 |
Aspinall CF, Zheleva D, Tighe A, Taylor SS. Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1. Oncotarget. PMID 26472023 DOI: 10.18632/Oncotarget.5507 |
0.399 |
|
| 2015 |
Bennett A, Bechi B, Tighe A, Thompson S, Procter DJ, Taylor SS. Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy. Oncotarget. 6: 20921-32. PMID 26320186 DOI: 10.18632/Oncotarget.4879 |
0.466 |
|
| 2015 |
Topham C, Tighe A, Ly P, Bennett A, Sloss O, Nelson L, Ridgway RA, Huels D, Littler S, Schandl C, Sun Y, Bechi B, Procter DJ, Sansom OJ, Cleveland DW, ... Taylor SS, et al. MYC Is a Major Determinant of Mitotic Cell Fate. Cancer Cell. 28: 129-40. PMID 26175417 DOI: 10.1016/J.Ccell.2015.06.001 |
0.539 |
|
| 2015 |
Matthews LC, Berry AA, Morgan DJ, Poolman TM, Bauer K, Kramer F, Spiller DG, Richardson RV, Chapman KE, Farrow SN, Norman MR, Williamson AJ, Whetton AD, Taylor SS, Tuckermann JP, et al. Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy. Proceedings of the National Academy of Sciences of the United States of America. 112: 5479-84. PMID 25847991 DOI: 10.1073/Pnas.1411356112 |
0.441 |
|
| 2013 |
Topham CH, Taylor SS. Mitosis and apoptosis: how is the balance set? Current Opinion in Cell Biology. 25: 780-5. PMID 23890995 DOI: 10.1016/J.Ceb.2013.07.003 |
0.384 |
|
| 2013 |
Woll P, Kjällquist U, Chowdhury O, Erlandsson R, Doolittle H, Ngara M, Anderson K, Giannoulatou E, Taylor S, Deng Q, Mead AJ, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark s, et al. Diverse Genetic Lesions In Myelodysplastic Syndromes Originate Exclusively In Rare MDS Stem Cells Blood. 122: 4195-4195. DOI: 10.1182/Blood.V122.21.4195.4195 |
0.304 |
|
| 2012 |
Lara-Gonzalez P, Westhorpe FG, Taylor SS. The spindle assembly checkpoint. Current Biology : Cb. 22: R966-80. PMID 23174302 DOI: 10.1016/J.Cub.2012.10.006 |
0.751 |
|
| 2012 |
Lara-Gonzalez P, Taylor SS. Cohesion fatigue explains why pharmacological inhibition of the APC/C induces a spindle checkpoint-dependent mitotic arrest. Plos One. 7: e49041. PMID 23145059 DOI: 10.1371/Journal.Pone.0049041 |
0.74 |
|
| 2012 |
Papantonis A, Kohro T, Baboo S, Larkin JD, Deng B, Short P, Tsutsumi S, Taylor S, Kanki Y, Kobayashi M, Li G, Poh HM, Ruan X, Aburatani H, Ruan Y, et al. TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed. The Embo Journal. 31: 4404-14. PMID 23103767 DOI: 10.1038/Emboj.2012.288 |
0.3 |
|
| 2012 |
Frame S, Aspinall C, O'Neil R, Hollick J, Taylor S, Hupp T, Blake D, Zheleva DI. Abstract 2814: Potent and selective small molecule inhibitors of polo-like kinase 1: Biological characterization Cancer Research. 72: 2814-2814. DOI: 10.1158/1538-7445.Am2012-2814 |
0.429 |
|
| 2011 |
Lara-Gonzalez P, Scott MI, Diez M, Sen O, Taylor SS. BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner. Journal of Cell Science. 124: 4332-45. PMID 22193957 DOI: 10.1242/Jcs.094763 |
0.738 |
|
| 2011 |
Westhorpe FG, Tighe A, Lara-Gonzalez P, Taylor SS. p31comet-mediated extraction of Mad2 from the MCC promotes efficient mitotic exit. Journal of Cell Science. 124: 3905-16. PMID 22100920 DOI: 10.1242/Jcs.093286 |
0.732 |
|
| 2011 |
Sakurikar N, Taylor SS, Chambers TC. Abstract 14: Role of Cdk1 and Bcl-2 proteins in mitotic cell death Cancer Research. 71: 14-14. DOI: 10.1158/1538-7445.Am2011-14 |
0.418 |
|
| 2010 |
Radulescu S, Ridgway RA, Appleton P, Kroboth K, Patel S, Woodgett J, Taylor S, Nathke IS, Sansom OJ. Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol Oncogene. 29: 6418-6427. PMID 20729907 DOI: 10.1038/Onc.2010.373 |
0.442 |
|
| 2010 |
Santaguida S, Tighe A, D'Alise AM, Taylor SS, Musacchio A. Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. The Journal of Cell Biology. 190: 73-87. PMID 20624901 DOI: 10.1083/Jcb.201001036 |
0.477 |
|
| 2010 |
Hewitt L, Tighe A, Santaguida S, White AM, Jones CD, Musacchio A, Green S, Taylor SS. Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex. The Journal of Cell Biology. 190: 25-34. PMID 20624899 DOI: 10.1083/Jcb.201002133 |
0.448 |
|
| 2010 |
Kassouf MT, Hughes JR, Taylor S, McGowan SJ, Soneji S, Green AL, Vyas P, Porcher C. Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells. Genome Research. 20: 1064-83. PMID 20566737 DOI: 10.1101/Gr.104935.110 |
0.323 |
|
| 2010 |
Ballabio E, Mitchell T, van Kester MS, Taylor S, Dunlop HM, Chi J, Tosi I, Vermeer MH, Tramonti D, Saunders NJ, Boultwood J, Wainscoat JS, Pezzella F, Whittaker SJ, Tensen CP, et al. MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential. Blood. 116: 1105-13. PMID 20448109 DOI: 10.1182/Blood-2009-12-256719 |
0.3 |
|
| 2010 |
Westhorpe FG, Diez MA, Gurden MD, Tighe A, Taylor SS. Re-evaluating the role of Tao1 in the spindle checkpoint. Chromosoma. 119: 371-9. PMID 20162290 DOI: 10.1007/S00412-010-0261-1 |
0.786 |
|
| 2010 |
Perera D, Taylor SS. Sgo1 establishes the centromeric cohesion protection mechanism in G2 before subsequent Bub1-dependent recruitment in mitosis. Journal of Cell Science. 123: 653-9. PMID 20124418 DOI: 10.1242/Jcs.059501 |
0.459 |
|
| 2010 |
Gurden MD, Holland AJ, van Zon W, Tighe A, Vergnolle MA, Andres DA, Spielmann HP, Malumbres M, Wolthuis RM, Cleveland DW, Taylor SS. Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F. Journal of Cell Science. 123: 321-30. PMID 20053638 DOI: 10.1242/Jcs.062075 |
0.628 |
|
| 2009 |
Tilston V, Taylor SS, Perera D. Inactivating the spindle checkpoint kinase Bub1 during embryonic development results in a global shutdown of proliferation. Bmc Research Notes. 2: 190. PMID 19772675 DOI: 10.1186/1756-0500-2-190 |
0.366 |
|
| 2009 |
Gascoigne KE, Taylor SS. How do anti-mitotic drugs kill cancer cells? Journal of Cell Science. 122: 2579-85. PMID 19625502 DOI: 10.1242/Jcs.039719 |
0.688 |
|
| 2009 |
McGuinness BE, Anger M, Kouznetsova A, Gil-Bernabé AM, Helmhart W, Kudo NR, Wuensche A, Taylor S, Hoog C, Novak B, Nasmyth K. Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint. Current Biology : Cb. 19: 369-80. PMID 19249208 DOI: 10.1016/J.Cub.2009.01.064 |
0.426 |
|
| 2009 |
Keen N, Taylor S. Mitotic drivers-inhibitors of the Aurora B Kinase Cancer and Metastasis Reviews. 28: 185-195. PMID 19189202 DOI: 10.1007/S10555-009-9184-9 |
0.344 |
|
| 2009 |
Amabile G, D'Alise AM, Iovino M, Jones P, Santaguida S, Musacchio A, Taylor S, Cortese R. The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts Cell Death and Differentiation. 16: 321-330. PMID 18974773 DOI: 10.1038/Cdd.2008.156 |
0.412 |
|
| 2008 |
Gascoigne KE, Taylor SS. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell. 14: 111-22. PMID 18656424 DOI: 10.1016/J.Ccr.2008.07.002 |
0.706 |
|
| 2008 |
Mac?rek L, Lindqvist A, Lim D, Lampson MA, Klompmaker R, Freire R, Clouin C, Taylor SS, Yaffe MB, Medema RH. Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery Nature. 455: 119-123. PMID 18615013 DOI: 10.1038/Nature07185 |
0.376 |
|
| 2008 |
Girdler F, Sessa F, Patercoli S, Villa F, Musacchio A, Taylor S. Molecular Basis of Drug Resistance in Aurora Kinases Chemistry and Biology. 15: 552-562. PMID 18559266 DOI: 10.1016/J.Chembiol.2008.04.013 |
0.312 |
|
| 2008 |
Tighe A, Staples O, Taylor S. Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores Journal of Cell Biology. 181: 893-901. PMID 18541701 DOI: 10.1083/Jcb.200712028 |
0.445 |
|
| 2008 |
Holland AJ, Taylor SS. Many faces of separase regulation. Seb Experimental Biology Series. 59: 99-112. PMID 18368920 |
0.506 |
|
| 2008 |
Taylor S, Peters JM. Polo and Aurora kinases - lessons derived from chemical biology Current Opinion in Cell Biology. 20: 77-84. PMID 18249108 DOI: 10.1016/J.Ceb.2007.11.008 |
0.402 |
|
| 2008 |
Brocardo M, Lei Y, Tighe A, Taylor SS, Mok MT, Henderson BR. Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival. The Journal of Biological Chemistry. 283: 5950-9. PMID 18160396 DOI: 10.1074/Jbc.M708775200 |
0.317 |
|
| 2007 |
Perera D, Tilston V, Hopwood JA, Barchi M, Boot-Handford RP, Taylor SS. Bub1 maintains centromeric cohesion by activation of the spindle checkpoint. Developmental Cell. 13: 566-79. PMID 17925231 DOI: 10.1016/J.Devcel.2007.08.008 |
0.462 |
|
| 2007 |
Tighe A, Ray-Sinha A, Staples OD, Taylor SS. GSK-3 inhibitors induce chromosome instability. Bmc Cell Biology. 8: 34. PMID 17697341 DOI: 10.1186/1471-2121-8-34 |
0.415 |
|
| 2007 |
Holland AJ, Böttger F, Stemmann O, Taylor SS. Protein phosphatase 2A and separase form a complex regulated by separase autocleavage. The Journal of Biological Chemistry. 282: 24623-32. PMID 17604273 DOI: 10.1074/Jbc.M702545200 |
0.601 |
|
| 2007 |
Vergnolle MA, Taylor SS. Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes. Current Biology : Cb. 17: 1173-9. PMID 17600710 DOI: 10.1016/J.Cub.2007.05.077 |
0.395 |
|
| 2007 |
Taylor SS, Hardwick KG, Sawin KE, Biggins S, Piatti S, Khodjakov A, Rieder CL, Salmon ED, Musacchio A. Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint". Science (New York, N.Y.). 316: 982; author reply 98. PMID 17510347 DOI: 10.1126/Science.1139484 |
0.373 |
|
| 2006 |
Guo C, Wu G, Chin JL, Bauman G, Moussa M, Wang F, Greenberg NM, Taylor SS, Xuan JW. Bub1 up-regulation and hyperphosphorylation promote malignant transformation in SV40 tag-induced transgenic mouse models. Molecular Cancer Research : McR. 4: 957-69. PMID 17189386 DOI: 10.1158/1541-7786.Mcr-06-0168 |
0.316 |
|
| 2006 |
Girdler F, Gascoigne KE, Eyers PA, Hartmuth S, Crafter C, Foote KM, Keen NJ, Taylor SS. Validating Aurora B as an anti-cancer drug target. Journal of Cell Science. 119: 3664-75. PMID 16912073 DOI: 10.1242/Jcs.03145 |
0.726 |
|
| 2006 |
Holland AJ, Taylor SS. Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction. Journal of Cell Science. 119: 3325-36. PMID 16868023 DOI: 10.1242/Jcs.03083 |
0.619 |
|
| 2005 |
Holt SV, Vergnolle MA, Hussein D, Wozniak MJ, Allan VJ, Taylor SS. Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint. Journal of Cell Science. 118: 4889-900. PMID 16219694 DOI: 10.1242/Jcs.02614 |
0.377 |
|
| 2005 |
Morrow CJ, Tighe A, Johnson VL, Scott MI, Ditchfield C, Taylor SS. Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20. Journal of Cell Science. 118: 3639-52. PMID 16046481 DOI: 10.1242/Jcs.02487 |
0.508 |
|
| 2005 |
Dai J, Sultan S, Taylor SS, Higgins JM. The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment. Genes & Development. 19: 472-88. PMID 15681610 DOI: 10.1101/Gad.1267105 |
0.405 |
|
| 2005 |
Ditchfield C, Keen N, Taylor SS. The Ipl1/Aurora kinase family: methods of inhibition and functional analysis in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 296: 371-81. PMID 15576945 DOI: 10.1385/1-59259-857-9:371 |
0.372 |
|
| 2004 |
Keen N, Taylor S. Aurora-kinase inhibitors as anticancer agents Nature Reviews Cancer. 4: 927-936. PMID 15573114 DOI: 10.1038/Nrc1502 |
0.382 |
|
| 2004 |
Tighe A, Johnson VL, Taylor SS. Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability. Journal of Cell Science. 117: 6339-53. PMID 15561772 DOI: 10.1242/Jcs.01556 |
0.422 |
|
| 2004 |
Taylor SS, Scott MI, Holland AJ. The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 12: 599-616. PMID 15289666 DOI: 10.1023/B:Chro.0000036610.78380.51 |
0.615 |
|
| 2004 |
Johnson VL, Scott MI, Holt SV, Hussein D, Taylor SS. Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression. Journal of Cell Science. 117: 1577-89. PMID 15020684 DOI: 10.1242/Jcs.01006 |
0.446 |
|
| 2003 |
Brunet S, Pahlavan G, Taylor S, Maro B. Functionality of the spindle checkpoint during the first meiotic division of mammalian oocytes Reproduction. 126: 443-450. PMID 14525526 DOI: 10.1530/Rep.0.1260443 |
0.427 |
|
| 2003 |
Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. The Journal of Cell Biology. 161: 267-80. PMID 12719470 DOI: 10.1083/Jcb.200208091 |
0.471 |
|
| 2001 |
Taylor SS, Hussein D, Wang Y, Elderkin S, Morrow CJ. Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells Journal of Cell Science. 114: 4385-4395. PMID 11792804 |
0.373 |
|
| 2001 |
Tighe A, Johnson VL, Albertella M, Taylor SS. Aneuploid colon cancer cells have a robust spindle checkpoint Embo Reports. 2: 609-614. PMID 11454737 DOI: 10.1093/Embo-Reports/Kve127 |
0.418 |
|
| 1999 |
Taylor SS. Chromosome segregation: Dual control ensures fidelity Current Biology. 9: R562-R564. PMID 10469560 DOI: 10.1016/S0960-9822(99)80355-8 |
0.42 |
|
| 1999 |
Rolls MM, Stein PA, Taylor SS, Ha E, McKeon F, Rapoport TA. A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein. The Journal of Cell Biology. 146: 29-44. PMID 10402458 DOI: 10.1083/Jcb.146.1.29 |
0.532 |
|
| 1998 |
Taylor SS, Ha E, McKeon F. The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase. The Journal of Cell Biology. 142: 1-11. PMID 9660858 DOI: 10.1083/Jcb.142.1.1 |
0.651 |
|
| 1997 |
Taylor SS, McKeon F. Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage. Cell. 89: 727-35. PMID 9182760 DOI: 10.1016/S0092-8674(00)80255-X |
0.661 |
|
| 1996 |
Larin Z, Taylor SS, Tyler-Smith C. A method for linking yeast artificial chromosomes Nucleic Acids Research. 24: 4192-4196. PMID 8932371 DOI: 10.1093/Nar/24.21.4192 |
0.371 |
|
| 1996 |
Taylor SS, Larin Z, Tyler-Smith C. Analysis of extrachromosomal structures containing human centromeric alphoid satellite DNA sequences in mouse cells Chromosoma. 105: 70-81. PMID 8753696 DOI: 10.1007/Bf02509516 |
0.369 |
|
| 1994 |
Taylor SS, Larin Z, Smith CT. Addition of functional human telomeres to YACs. Human Molecular Genetics. 3: 1383-6. PMID 7987319 DOI: 10.1093/Hmg/3.8.1383 |
0.353 |
|
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