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Justine L. Lam, Ph.D. - Publications

Affiliations: 
2006 University of California, San Francisco, San Francisco, CA 
Area:
Pharmacology
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6 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Stypinski D, Fostvedt L, Lam JL, Vaz A, Johnson TR, Boerma JS, Pithavala YK. Metabolism, Excretion, and Pharmacokinetics of Lorlatinib (PF-06463922) and Evaluation of the Impact of Radiolabel Position and Other Factors on Comparability of Data Across 2 ADME Studies. Journal of Clinical Pharmacology. PMID 32441835 DOI: 10.1002/Jcph.1621  0.312
2016 Lam JL, Vaz A, Hee B, Liang Y, Yang X, Shaik MN. Metabolism, excretion and pharmacokinetics of [(14)C]Glasdegib (PF-04449913) in healthy volunteers following oral administration. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-42. PMID 27866461 DOI: 10.1080/00498254.2016.1261307  0.429
2013 Yanochko GM, Vitsky A, Heyen JR, Hirakawa B, Lam JL, May J, Nichols T, Sace F, Trajkovic D, Blasi E. Pan-FGFR inhibition leads to blockade of FGF23 signaling, soft tissue mineralization, and cardiovascular dysfunction. Toxicological Sciences : An Official Journal of the Society of Toxicology. 135: 451-64. PMID 23872713 DOI: 10.1093/toxsci/kft161  0.495
2013 Varma MV, Lin J, Bi YA, Rotter CJ, Fahmi OA, Lam JL, El-Kattan AF, Goosen TC, Lai Y. Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 966-74. PMID 23393219 DOI: 10.1124/dmd.112.050583  0.538
2006 Lam JL, Okochi H, Huang Y, Benet LZ. In vitro and in vivo correlation of hepatic transporter effects on erythromycin metabolism: characterizing the importance of transporter-enzyme interplay. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1336-44. PMID 16698890 DOI: 10.1124/Dmd.106.009258  0.675
2004 Lam JL, Benet LZ. Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1311-6. PMID 15483198 DOI: 10.1124/Dmd.32.11.1311  0.641
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