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Seyedmehdi Shojaee, Ph.D. - Publications

Affiliations: 
2013 Genetic, Molecular, and Cell Biology University of Southern California, Los Angeles, CA, United States 
Area:
Oncology
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chan LN, Murakami MA, Robinson ME, Caeser R, Sadras T, Lee J, Cosgun KN, Kume K, Khairnar V, Xiao G, Ahmed MA, Aghania E, Deb G, Hurtz C, Shojaee S, et al. Signalling input from divergent pathways subverts B cell transformation. Nature. PMID 32699415 DOI: 10.1038/S41586-020-2513-4  0.7
2019 Chan LN, Murakami MA, Caesar R, Hurtz C, Kume K, Sadras T, Shojaee S, Pölönen P, Ugale A, Lee J, Cosgun KN, Geng H, Heinäniemi M, Lohi O, Wiita AP, et al. Signaling Input from Divergent Pathways Subverts Malignant B-Cell Transformation Blood. 134: 3944-3944. DOI: 10.1182/Blood-2019-130774  0.706
2018 Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, et al. Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. PMID 29849140 DOI: 10.1038/S41586-018-0164-5  0.527
2018 Chan LN, Shojaee S, Hurtz C, Auer F, Chen Z, Cosgun KN, Geng H, Sadras T, White DL, Muschen M. Divergent Evolutionary Trajectories of Erk- and Stat5-Activating Lesions in Acute Lymphoblastic Leukemia Blood. 132: 568-568. DOI: 10.1182/Blood-2018-99-115536  0.53
2018 Aravanis AA, Oxnard GR, Maddala T, Hubbell E, Venn O, Jamshidi A, Shen L, Amini H, Beausang JA, Betts C, Civello D, Davydov K, Fazullina S, Filippova D, Gnerre S, ... ... Shojaee S, et al. Abstract LB-343: Development of plasma cell-free DNA (cfDNA) assays for early cancer detection: first insights from the Circulating Cell-Free Genome Atlas Study (CCGA) Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-343  0.328
2017 Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 1-5. PMID 28192788 DOI: 10.1038/Nature21076  0.6
2016 Shojaee S, Chan LN, Buchner M, Cazzaniga V, Cosgun KN, Geng H, Qiu YH, von Minden MD, Ernst T, Hochhaus A, Cazzaniga G, Melnick A, Kornblau SM, Graeber TG, Wu H, et al. PTEN opposes negative selection and enables oncogenic transformation of pre-B cells. Nature Medicine. PMID 26974310 DOI: 10.1038/Nm.4062  0.716
2016 Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, et al. Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. PMID 26958840 DOI: 10.1038/Nature16997  0.542
2016 Cao Q, Gearhart MD, Gery S, Shojaee S, Yang H, Sun H, Lin DC, Bai JW, Mead M, Zhao Z, Chen Q, Chien WW, Alkan S, Alpermann T, Haferlach T, et al. BCOR regulates myeloid cell proliferation and differentiation. Leukemia. PMID 26847029 DOI: 10.1038/Leu.2016.2  0.605
2016 Chan LN, Hurtz C, Xiao G, Shojaee S, Caeser R, Geng H, Melnick A, Müschen M. BCL6 Is Critical to Overcome Oncogene-Induced Senescence in RAS-Mediated B Cell Transformation Blood. 128: 438-438. DOI: 10.1182/Blood.V128.22.438.438  0.667
2015 Shojaee S, Caeser R, Buchner M, Park E, Swaminathan S, Hurtz C, Geng H, Chan LN, Klemm L, Hofmann WK, Qiu YH, Zhang N, Coombes KR, Paietta E, Molkentin J, et al. Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia. Cancer Cell. 28: 114-28. PMID 26073130 DOI: 10.1016/J.Ccell.2015.05.008  0.784
2015 Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, et al. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 521: 357-61. PMID 25799995 DOI: 10.1038/Nature14231  0.741
2015 Geng H, Hurtz C, Lenz KB, Chen Z, Baumjohann D, Thompson S, Goloviznina NA, Chen WY, Huan J, LaTocha D, Ballabio E, Xiao G, Lee JW, Deucher A, Qi Z, ... ... Shojaee S, et al. Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia. Cancer Cell. 27: 409-25. PMID 25759025 DOI: 10.1016/J.Ccell.2015.02.003  0.802
2015 Li Q, Hurtz C, Shojaee S, Chen Z, Geng H, Xiao G, Loh ML, Ye BH, Melnick A, Muschen M. Identification of BCL6 As a Therapeutic Target in RAS-Driven Acute Lymphoblastic Leukemia Blood. 126: 556-556. DOI: 10.1182/Blood.V126.23.556.556  0.658
2015 Chan LN, Chen Z, Braas D, Geng H, Hurtz C, Shojaee S, Cazzaniga V, Ng C, Ernst T, Hochhaus A, Kornblau SM, Cazzaniga G, Liu G, Milne T, Koeffler HP, et al. B-Lymphoid Transcription Factors Restrict Glycolytic Energy Supply for Oncogenic Signaling Blood. 126: 1255-1255. DOI: 10.1182/Blood.V126.23.1255.1255  0.677
2015 Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Loh ML, Jung JU, Coligan JE, Bolland S, et al. Abstract 2075: Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia Cancer Research. 75: 2075-2075. DOI: 10.1158/1538-7445.Am2015-2075  0.74
2015 Chan LN, Braas D, Hurtz C, Shojaee S, Geng H, Cazzaniga V, Ng C, Masouleh BK, Qiu YH, Zhang N, Coombes KR, Ernst T, Cazzaniga G, Hochhaus A, Kornblau S, et al. Abstract 1124: Transcriptional control of B cell identity restricts metabolic fitness in human leukemia Cancer Research. 75: 1124-1124. DOI: 10.1158/1538-7445.Am2015-1124  0.529
2014 Chen Z, Shojaee S, Geng H, Lee J, Buchner M, Klemm L, Lowell CA, Paietta E, Willman CL, Carroll WL, Melnick A, Jung JU, Jumaa H, Coligan JE, Bolland S, et al. Harnessing Negative B Cell Selection to Overcome Drug-Resistance in Acute Lymphoblastic Leukemia Blood. 124: 792-792. DOI: 10.1182/Blood.V124.21.792.792  0.724
2014 Chan LN, Braas D, Hurtz C, Shojaee S, Kharabi Masouleh B, Geng H, Ernst T, Hochhaus A, Graeber T, Muschen M. Lineage-Specific Metabolic Reprogramming Reveals LKB1 as Therapeutic Target in Acute Lymphoblastic Leukemia Blood. 124: 783-783. DOI: 10.1182/Blood.V124.21.783.783  0.681
2014 Geng H, Hurtz C, Baumjohann D, Chen Z, Chen W, Ballabio E, Xiao G, Lee J, Deucher A, Qi Z, Huang C, Nahar R, Kweon S, Shojaee S, Chan LN, et al. Self-Enforcing Feedback Activation Between BCL6 and Tonic Pre-B Cell Receptor Signaling in Acute Lymphoblastic Leukemia Blood. 124: 284-284. DOI: 10.1182/Blood.V124.21.284.284  0.821
2014 Shojaee S, Cazzaniga V, Schjerven H, Buchner M, Hurtz C, Geng H, Hochhaus A, Cazzaniga G, Melnick AM, Kornblau SM, Graeber TG, Muschen M. PTEN Is Essential for Normal Cytokine Signaling and Oncogenic Transformation of Pre-B Cells Blood. 124: 262-262. DOI: 10.1182/Blood.V124.21.262.262  0.748
2014 Shojaee S, Muschen M. Biology and targeting options for kinase signaling in acute lymphoblastic leukemia Aacr Education Book. 2014: 91-94. DOI: 10.1158/Aacr.Edb-14-1332  0.611
2014 Chan LN, Shojaee S, Hurtz C, Geng H, Ng C, Kharabi B, Müschen M. Abstract 2447: Lineage-specific metabolic reprogramming in BCR-ABL1-driven leukemia Cancer Research. 74: 2447-2447. DOI: 10.1158/1538-7445.Am2014-2447  0.691
2013 Hertzman Johansson C, Azimi A, Frostvik Stolt M, Shojaee S, Wiberg H, Grafström E, Hansson J, Egyházi Brage S. Association of MITF and other melanosome-related proteins with chemoresistance in melanoma tumors and cell lines. Melanoma Research. 23: 360-5. PMID 23921446 DOI: 10.1097/Cmr.0B013E328362F9Cd  0.342
2013 Hsieh YT, Gang EJ, Geng H, Park E, Huantes S, Chudziak D, Dauber K, Schaefer P, Scharman C, Shimada H, Shojaee S, Klemm L, Parameswaran R, Loh M, Kang ES, et al. Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy. Blood. 121: 1814-8. PMID 23319569 DOI: 10.1182/Blood-2012-01-406272  0.361
2013 Chen Z, Shojaee S, Geng H, Lee J, Buchner M, Klemm L, Lowell CA, Paietta E, Willman CL, Carroll WL, Melnick AM, Jung JU, Jumaa H, Coligan JE, Bolland S, et al. Inhibitory Receptors and Phosphatases Enable Oncogenic Tyrosine Kinase Signaling In B Cell Lineage Leukemia Blood. 122: 229-229. DOI: 10.1182/Blood.V122.21.229.229  0.738
2013 Silveira V, Shojaee S, Müschen M. Abstract A55: Induced hyperactivation of Ras-MAPK in chronic myeloid leukemia: role of negative feedback signaling Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A55  0.684
2013 Shojaee S, Buchner M, Gery S, Geng H, Chan LN, Melnick A, Koeffler PH, Müschen M. Abstract 2334: Targeting inhibitory phosphatase signaling in Ph+ ALL. Cancer Research. 73: 2334-2334. DOI: 10.1158/1538-7445.Am2013-2334  0.721
2012 Geng H, Brennan S, Milne TA, Chen WY, Li Y, Hurtz C, Kweon SM, Zickl L, Shojaee S, Neuberg D, Huang C, Biswas D, Xin Y, Racevskis J, Ketterling RP, et al. Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. Cancer Discovery. 2: 1004-23. PMID 23107779 DOI: 10.1158/2159-8290.Cd-12-0208  0.475
2012 Cao Q, Gery S, Shojaee S, Gearhart M, Bardwell V, Muschen M, Koeffler HP. BCOR Is Involved in Myeloid Cell Growth Control by Regulating Hox Genes Blood. 120: 3445-3445. DOI: 10.1182/Blood.V120.21.3445.3445  0.633
2012 Chen Z, Geng H, Buchner M, Klemm L, Hemati K, Shojaee S, Tak MW, Coligan JE, Carroll WL, Willman CL, Muschen M. ITIM-Containing Inhibitory Receptors Are Required to Balance Oncogenic Signaling Strength in Ph+ ALL Blood. 120: 291-291. DOI: 10.1182/Blood.V120.21.291.291  0.674
2012 Chen Z, Geng H, Klemm L, Buchner M, Hemati K, Shojaee S, Alexander WS, Carroll WL, Willman CL, Muschen M. Suppressor of Cytokine Signaling (SOCS) Molecules Are Critical to Balance Oncogenic Signaling Strength in Ph+ ALL. Blood. 120: 2563-2563. DOI: 10.1182/Blood.V120.21.2563.2563  0.71
2012 Shojaee S, Buchner M, Swaminathan S, Geng H, Chan L, Bothe M, Chen Z, Melnick A, Molkentin J, Martin G, Koeffler HP, Muschen M. Negative Feedback Signaling Enables Leukemic Transformation by Oncogenic Tyrosine Kinases Blood. 120: 1352-1352. DOI: 10.1182/Blood.V120.21.1352.1352  0.783
2012 Shojaee S, Geng H, Gearhart M, Bardwell V, Muschen M. BCL6 Interacting Corepressor (BCOR) Functions As Lineage-Specific Tumor Suppressor in B Lymphoid and Myeloid Leukemia Blood. 120: 1301-1301. DOI: 10.1182/Blood.V120.21.1301.1301  0.661
2011 Duy C, Hurtz C, Shojaee S, Cerchietti L, Geng H, Swaminathan S, Klemm L, Kweon SM, Nahar R, Braig M, Park E, Kim YM, Hofmann WK, Herzog S, Jumaa H, et al. BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature. 473: 384-8. PMID 21593872 DOI: 10.1038/Nature09883  0.777
2011 Shojaee S, Buchner M, Geng H, Melnick A, Gery S, Molkentin J, Koeffler P, Muschen M. DUSP6-Mediated Negative Feedback to Oncogenic Tyrosine Kinase Signaling Prevents Excessive Accumulation of ROS and Enables Leukemia Cell Survival Blood. 118: 1479-1479. DOI: 10.1182/Blood.V118.21.1479.1479  0.728
2011 Shojaee S, Buchner M, Geng H, Silvia B, Koeffler P, Muschen M. Targeting Inhibitory Phosphatases in Tyrosine Kinase-Driven Leukemias Blood. 118: 1382-1382. DOI: 10.1182/Blood.V118.21.1382.1382  0.72
2010 Duy C, Yu JJ, Nahar R, Swaminathan S, Kweon SM, Polo JM, Valls E, Klemm L, Shojaee S, Cerchietti L, Schuh W, Jäck HM, Hurtz C, Ramezani-Rad P, Herzog S, et al. BCL6 is critical for the development of a diverse primary B cell repertoire. The Journal of Experimental Medicine. 207: 1209-21. PMID 20498019 DOI: 10.1084/Jem.20091299  0.787
2010 Shojaee S, Garcia C, Wu H, Muschen M. The Tumor Suppressor PTEN Is Required to Prevent Cellular Senescence and Cell Cycle Arrest In B Cell Lineage and Chronic Myeloid Leukemia Blood. 116: 513-513. DOI: 10.1182/Blood.V116.21.513.513  0.721
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