Douglas D. Richman - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, Microbiology Biology

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Inzaule SC, Siedner MJ, Little SJ, Avila-Rios S, Ayitewala A, Bosch RJ, Calvez V, Ceccherini-Silberstein F, Charpentier C, Descamps D, Eshleman SH, Fokam J, Frenkel LM, Gupta RK, Ioannidis JPA, ... ... Richman DD, et al. Recommendations on data sharing in HIV drug resistance research. Plos Medicine. 20: e1004293. PMID 37738247 DOI: 10.1371/journal.pmed.1004293  0.482
2022 Beliakova-Bethell N, Manousopoulou A, Deshmukh S, Mukim A, Richman DD, Garbis SD, Spina CA. Integrated proteomics and transcriptomics analyses identify novel cell surface markers of HIV latency. Virology. 573: 50-58. PMID 35714458 DOI: 10.1016/j.virol.2022.06.003  0.482
2021 Marques-Gomes J, Salt MJ, Pereira-Neto R, Barteldes FS, Gouveia-Barros V, Carvalho A, d'Arminio-Monforte A, De-la-Torre-Rosas A, Harris A, Esteves C, Maor C, Mora C, Oliveira C, Sousa C, Richman DD, et al. Development of the HIV360 international core set of outcome measures for adults living with HIV: A consensus process. Hiv Medicine. PMID 34964226 DOI: 10.1111/hiv.13221  0.421
2021 Papasavvas E, Azzoni L, Ross BN, Fair M, Yuan Z, Gyampoh K, Mackiewicz A, Sciorillo AC, Pagliuzza A, Lada SM, Wu G, Goh SL, Bahnck-Teets C, Holder DJ, Zuck PD, ... ... Richman D, et al. Intact Human Immunodeficiency Virus (HIV) Reservoir Estimated by the Intact Proviral DNA Assay Correlates With Levels of Total and Integrated DNA in the Blood During Suppressive Antiretroviral Therapy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 72: 495-498. PMID 33527127 DOI: 10.1093/cid/ciaa809  0.49
2020 Vollbrecht T, Angerstein AO, Menke B, Kumar NM, de Oliveira MF, Richman DD, Guatelli JC. Inconsistent reversal of HIV-1 latency ex vivo by antigens of HIV-1, CMV, and other infectious agents. Retrovirology. 17: 36. PMID 33228686 DOI: 10.1186/s12977-020-00545-x  0.537
2020 Bakkour S, Deng X, Bacchetti P, Grebe E, Montalvo L, Worlock A, Stone M, Deeks SG, Richman DD, Busch MP. Replicate Aptima assay for quantifying residual plasma viremia in individuals on ART. Journal of Clinical Microbiology. PMID 32967900 DOI: 10.1128/JCM.01400-20  0.415
2020 Abdel-Mohsen M, Richman D, Siliciano RF, Nussenzweig MC, Howell BJ, Martinez-Picado J, Chomont N, Bar KJ, Yu XG, Lichterfeld M, Alcami J, Hazuda D, Bushman F, Siliciano JD, Betts MR, et al. Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nature Medicine. PMID 32895573 DOI: 10.1038/S41591-020-1022-1  0.576
2020 Papasavvas E, Azzoni L, Ross BN, Fair M, Yuan Z, Gyampoh K, Mackiewicz A, Sciorillo AC, Paggliuzza A, Lada SM, Wu G, Goh SL, Bahnck-Teets C, Holder DJ, Zuck PD, ... ... Richman D, et al. Intact HIV reservoir estimated by the intact proviral DNA assay correlates with levels of total and integrated DNA in the blood during suppressive antiretroviral therapy. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32556126 DOI: 10.1093/Cid/Ciaa809  0.553
2020 Stone M, Rosenbloom D, Bacchetti P, Deng X, Dimapasoc M, Keating S, Bakkour S, Richman D, Mellors J, Deeks S, Lai J, Beg S, Siliciano J, Pagliuzza A, Chomont N, et al. Assessing suitability of next-generation viral outgrowth assays as proxies for classic QVOA to measure HIV-1 latent reservoir size. The Journal of Infectious Diseases. PMID 32147687 DOI: 10.1093/Infdis/Jiaa089  0.507
2020 Hermans LE, Carmona S, Nijhuis M, Tempelman HA, Richman DD, Moorhouse M, Grobbee DE, Venter WDF, Wensing AMJ. Virological suppression and clinical management in response to viremia in South African HIV treatment program: A multicenter cohort study. Plos Medicine. 17: e1003037. PMID 32097428 DOI: 10.1371/Journal.Pmed.1003037  0.366
2020 Smith D, Delport W, Butler D, Little S, Richman D, Pond SK. Response to Comment on "The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men" Science Translational Medicine. 2: 501r1. PMID 21532938 DOI: 10.1126/Scitranslmed.3001473  0.558
2019 LaVergne S, Gaufin T, Richman D. Bacteremia and Severe Cellulitis. Open Forum Infectious Diseases. 6: ofz282. PMID 31334299 DOI: 10.1093/Ofid/Ofz282  0.336
2019 Rosenbloom DIS, Bacchetti P, Stone M, Deng X, Bosch RJ, Richman DD, Siliciano JD, Mellors JW, Deeks SG, Ptak RG, Hoh R, Keating SM, Dimapasoc M, Massanella M, Lai J, et al. Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size. Plos Computational Biology. 15: e1006849. PMID 30978183 DOI: 10.1371/Journal.Pcbi.1006849  0.439
2019 Richman DD, Huang K, Lada SM, Sun X, Jain S, Massanella M, Menke B. Replication competence of virions induced from CD4+ lymphocytes latently infected with HIV. Retrovirology. 16: 4. PMID 30770748 DOI: 10.1186/S12977-019-0466-1  0.566
2019 Beliakova-Bethell N, Mukim A, White CH, Deshmukh S, Abewe H, Richman DD, Spina CA. Histone deacetylase inhibitors induce complex host responses that contribute to differential potencies of these compounds in HIV reactivation. The Journal of Biological Chemistry. PMID 30745362 DOI: 10.1074/Jbc.Ra118.005185  0.552
2019 Fromentin R, Massanella M, Vandergeeten C, Morcilla V, Chiu WW, Looney D, Ramgopal M, Richman DD, Trautmann L, Palmer S, Chomont N. Large in vivo expansion and subsequent partial contraction of a T cell clone carrying a defective HIV genome reflect the dynamics of the HIV reservoir during ART Journal of Virus Eradication. 5: 13. DOI: 10.1016/S2055-6640(20)31044-X  0.552
2019 Papasavvas E, Azzoni L, Tebas P, Mounzer K, Kostman JR, Richman D, Chomont N, Howell B, Montaner LJ. Distinct HIV reservoir measures correlate with defective but not intact pro-viral DNA Journal of Virus Eradication. 5: 7. DOI: 10.1016/S2055-6640(20)30087-X  0.507
2018 Massanella M, Yek C, Lada SM, Nakazawa M, Shefa N, Huang K, Richman DD. Improved assays to measure and characterize the inducible HIV reservoir. Ebiomedicine. PMID 30316868 DOI: 10.1016/J.Ebiom.2018.09.036  0.545
2018 Lada SM, Huang K, VanBelzen DJ, Montaner LJ, O'Doherty U, Richman DD. Quantitation of Integrated HIV Provirus by Pulsed-Field Gel Electrophoresis and Droplet Digital PCR. Journal of Clinical Microbiology. PMID 30232127 DOI: 10.1128/Jcm.01158-18  0.547
2018 Lofano G, Gorman MJ, Yousif AS, Yu WH, Fox JM, Dugast AS, Ackerman ME, Suscovich TJ, Weiner J, Barouch D, Streeck H, Little S, Smith D, Richman D, Lauffenburger D, et al. Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement. Science Immunology. 3. PMID 30120121 DOI: 10.1126/Sciimmunol.Aat7796  0.358
2018 Günthard HF, Calvez V, Paredes R, Pillay D, Shafer RW, Wensing AM, Jacobsen DM, Richman DD. Human Immunodeficiency Virus Drug Resistance: 2018 Recommendations of the International Antiviral Society-USA Panel. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30052811 DOI: 10.1093/Cid/Ciy463  0.468
2018 Papasavvas E, Lada SM, Joseph J, Yin X, Liu Q, Azzoni L, Mounzer K, Kostman JR, Richman D, Montaner LJ. Analytical antiretroviral therapy interruption does not irreversibly change preinterruption levels of cellular HIV. Aids (London, England). 32: 1763-1772. PMID 30045057 DOI: 10.1097/Qad.0000000000001909  0.556
2018 Papasavvas E, Lada SM, Joseph J, Yin X, Liu Q, Azzoni L, Mounzer K, Kostman JR, Richman D, Montaner LJ. Analytical ART interruption does not irreversibly change pre-interruption levels of cellular HIV. Aids (London, England). PMID 29894387 DOI: 10.1097/QAD.0000000000001909  0.479
2018 Rothenberger M, Wagner JE, Haase A, Richman D, Grzywacz B, Strain M, Lada S, Estes J, Fletcher CV, Podany AT, Anderson J, Schmidt T, Wietgrefe S, Schacker T, Verneris MR. Transplantation of CCR5∆32 Homozygous Umbilical Cord Blood in a Child With Acute Lymphoblastic Leukemia and Perinatally Acquired HIV Infection. Open Forum Infectious Diseases. 5: ofy090. PMID 29868623 DOI: 10.1093/Ofid/Ofy090  0.522
2018 White CH, Beliakova-Bethell N, Lada SM, Breen MS, Hurst TP, Spina CA, Richman DD, Frater J, Magiorkinis G, Woelk CH. Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment. Frontiers in Immunology. 9: 603. PMID 29706951 DOI: 10.3389/Fimmu.2018.00603  0.496
2018 Abdel-Mohsen M, Kuri-Cervantes L, Grau-Exposito J, Spivak AM, Nell RA, Tomescu C, Vadrevu SK, Giron LB, Serra-Peinado C, Genescà M, Castellví J, Wu G, Del Rio Estrada PM, González-Navarro M, Lynn K, ... ... Richman D, et al. CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells. Science Translational Medicine. 10. PMID 29669853 DOI: 10.1126/Scitranslmed.Aar6759  0.494
2018 Ruggiero A, Cozzi-Lepri A, Beloukas A, Richman D, Khoo S, Phillips A, Geretti AM. Factors Associated With Persistence of Plasma HIV-1 RNA During Long-term Continuously Suppressive Firstline Antiretroviral Therapy. Open Forum Infectious Diseases. 5: ofy032. PMID 29507867 DOI: 10.1093/Ofid/Ofy032  0.489
2017 Sadanand S, Das J, Chung AW, Schoen MK, Lane S, Suscovich TJ, Streeck H, Smith D, Little S, Lauffenburger DA, Richman D, Alter G. Temporal variation in HIV-specific IgG subclass Abs during acute infection differentiates spontaneous controllers from chronic progressors. Aids (London, England). PMID 29239894 DOI: 10.1097/Qad.0000000000001716  0.542
2017 Cummins NW, Rizza S, Litzow MR, Hua S, Lee GQ, Einkauf K, Chun TW, Rhame F, Baker JV, Busch MP, Chomont N, Dean PG, Fromentin R, Haase AT, Hampton D, ... ... Richman DD, et al. Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study. Plos Medicine. 14: e1002461. PMID 29182633 DOI: 10.1371/Journal.Pmed.1002461  0.579
2017 Hermans LE, Moorhouse M, Carmona S, Grobbee DE, Hofstra LM, Richman DD, Tempelman HA, Venter WDF, Wensing AMJ. Effect of HIV-1 low-level viraemia during antiretroviral therapy on treatment outcomes in WHO-guided South African treatment programmes: a multicentre cohort study. The Lancet. Infectious Diseases. PMID 29158101 DOI: 10.1016/S1473-3099(17)30681-3  0.544
2017 Chaillon A, Gianella S, Lada SM, Perez-Santiago J, Jordan P, Ignacio C, Karris M, Richman D, Mehta SR, Little SJ, Wertheim JO, Smith DM. Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc. Journal of Virology. PMID 29142136 DOI: 10.1128/Jvi.01589-17  0.594
2017 Henrich TJ, Hatano H, Bacon O, Hogan LE, Rutishauser R, Hill A, Kearney MF, Anderson EM, Buchbinder SP, Cohen SE, Abdel-Mohsen M, Pohlmeyer CW, Fromentin R, Hoh R, Liu AY, ... ... Richman DD, et al. HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study. Plos Medicine. 14: e1002417. PMID 29112956 DOI: 10.1371/Journal.Pmed.1002417  0.571
2017 Wagner GA, Landais E, Caballero G, Phung P, Kosakovsky Pond SL, Poignard P, Richman DD, Little SJ, Smith DM. Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response. Journal of Virology. PMID 28615205 DOI: 10.1128/Jvi.00475-17  0.569
2017 Yek C, Massanella M, Peling T, Lednovich K, Nair SV, Worlock A, Vargas M, Gianella S, Ellis RJ, Strain MC, Busch MP, Nugent CT, Richman DD. Evaluation of the Aptima HIV-1 Quant Dx Assay for HIV-1 RNA Quantitation in Different Biological Specimen Types. Journal of Clinical Microbiology. PMID 28592548 DOI: 10.1128/Jcm.00425-17  0.552
2017 Beliakova-Bethell N, Hezareh M, Wong JK, Strain MC, Lewinski MK, Richman DD, Spina CA. Relative efficacy of T cell stimuli as inducers of productive HIV-1 replication in latently infected CD4 lymphocytes from patients on suppressive cART. Virology. 508: 127-133. PMID 28527342 DOI: 10.1016/J.Virol.2017.05.008  0.531
2017 Choi JY, Pond SLK, Anderson CM, Richman DD, Smith DM. Molecular Features of the V1-V4 Coding Region of Sexually Transmitted HIV-1. The Journal of Infectious Diseases. PMID 28419276 DOI: 10.1093/Infdis/Jix184  0.448
2017 Honeycutt JB, Thayer WO, Baker CE, Ribeiro RM, Lada SM, Cao Y, Cleary RA, Hudgens MG, Richman DD, Garcia JV. HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy. Nature Medicine. PMID 28414330 DOI: 10.1038/Nm.4319  0.587
2017 Richman DD. HIV: Finding latent needles in a haystack. Nature. 543: 499-500. PMID 28297707 DOI: 10.1038/Nature21899  0.585
2017 Vesa J, Chaillon A, Wagner GA, Anderson CM, Richman DD, Smith DM, Little SJ. Increased HIV-1 superinfection risk in carriers of specific human leukocyte antigen alleles. Aids (London, England). PMID 28244954 DOI: 10.1097/Qad.0000000000001445  0.485
2017 Keating SM, Stone M, Deng X, Mellors J, Bakkour S, Richman D, Gorelick R, Lifson J, Jennings C, Stengelin M, Wu G, Howell BJ, Bacchetti P, Busch MP. Blinded evaluation of ultrasensitive assays of HIV in plasma Journal of Virus Eradication. 3: 24-25. DOI: 10.1016/S2055-6640(20)30625-7  0.504
2017 Stone M, Rosenbloom D, Bacchetti P, Deng X, Busch M, Dimapasoc M, Keating S, Richman D, Mellors J, Deeks S, Siliciano J, Chomont N, Ptak R. Next generation viral outgrowth assays as proxies for classic QVOA to measure HIV-1 reservoir size Journal of Virus Eradication. 3: 17. DOI: 10.1016/S2055-6640(20)30599-9  0.546
2017 Fromentin R, Massanella M, Vandergeeten C, Barton K, Hiener B, Chiu WW, Looney D, Ramgopal M, Richman DD, Trautmann L, Palmer S, Chomont N. In vivo massive expansion of a T-cell clone carrying a defective HIV genome: implication for the measurement of the HIV reservoir Journal of Virus Eradication. 3: 21-22. DOI: 10.1016/S2055-6640(20)30544-6  0.556
2016 Chaillon A, Gianella S, Little SJ, Caballero G, Barin F, Kosakovsky Pond S, Richman DD, Smith DM, Mehta SR. Characterizing the multiplicity of HIV founder variants during sexual transmission among MSM. Virus Evolution. 2: vew012. PMID 30186625 DOI: 10.1093/Ve/Vew012  0.476
2016 Laird Smith M, Murrell B, Eren K, Ignacio C, Landais E, Weaver S, Phung P, Ludka C, Hepler L, Caballero G, Pollner T, Guo Y, Richman D, Poignard P, et al. Rapid Sequencing of CompleteGenes from Primary HIV-1 Samples. Virus Evolution. 2: vew018. PMID 29492273 DOI: 10.1093/Ve/Vew018  0.405
2016 White CH, Moesker B, Beliakova-Bethell N, Martins LJ, Spina CA, Margolis DM, Richman DD, Planelles V, Bosque A, Woelk CH. Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model. Plos Pathogens. 12: e1006026. PMID 27898737 DOI: 10.1371/Journal.Ppat.1006026  0.623
2016 Karris MY, Umlauf A, Vaida F, Richman D, Little S, Smith D. A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics. Medicine. 95: e5315. PMID 27858912 DOI: 10.1097/Md.0000000000005315  0.552
2016 Wagner GA, Chaillon A, Liu S, Franklin DR, Caballero G, Kosakovsky Pond SL, Vaida F, Heaton RK, Letendre SL, Grant I, Richman DD, Smith DM. HIV-associated neurocognitive disorder is associated with HIV-1 dual infection. Aids (London, England). PMID 27536983 DOI: 10.1097/Qad.0000000000001237  0.6
2016 Bruner KM, Murray AJ, Pollack RA, Soliman MG, Laskey SB, Capoferri AA, Lai J, Strain MC, Lada SM, Hoh R, Ho YC, Richman DD, Deeks SG, Siliciano JD, Siliciano RF. Defective proviruses rapidly accumulate during acute HIV-1 infection. Nature Medicine. PMID 27500724 DOI: 10.1038/Nm.4156  0.602
2016 Lee SA, Bacchetti P, Chomont N, Fromentin R, Lewin SR, O'Doherty U, Palmer S, Richman DD, Siliciano JD, Yukl SA, Deeks SG, Burbelo PD. Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy. Plos One. 11: e0160192. PMID 27483366 DOI: 10.1371/Journal.Pone.0160192  0.557
2016 Deeks SG, Lewin SR, Ross AL, Ananworanich J, Benkirane M, Cannon P, Chomont N, Douek D, Lifson JD, Lo YR, Kuritzkes D, Margolis D, Mellors J, Persaud D, Tucker JD, ... ... Richman D, et al. International AIDS Society global scientific strategy: towards an HIV cure 2016. Nature Medicine. PMID 27400264 DOI: 10.1038/Nm.4108  0.561
2016 Mehta SR, Murrell B, Anderson CM, Kosakovsky Pond SL, Wertheim JO, Young JA, Freitas L, Richman DD, Mathews WC, Scheffler K, Little SJ, Smith DM. Using HIV Sequence and Epidemiologic Data to Assess the Effect of Self-referral Testing for Acute HIV Infection on Incident Diagnoses in San Diego, California. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 27174704 DOI: 10.1093/Cid/Ciw161  0.6
2016 Richman DD. HIV is putting up less resistance. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 26962077 DOI: 10.1093/Cid/Ciw130  0.469
2016 Panichsillapakit T, Patel D, Santangelo J, Richman DD, Little SJ, Smith DM. Colorectal Disorders in Acute Human Immunodeficiency Virus Infection: A Case Series. Open Forum Infectious Diseases. 3: ofw014. PMID 26925432 DOI: 10.1093/Ofid/Ofw014  0.552
2016 Gianella S, Anderson C, Var SR, Oliveira MF, Lada S, Vargas M, Massanella M, Little S, Richman D, Strain M, Pérez-Santiago J, Smith D. Replication of Human Herpes Viruses is Associated with Greater HIV DNA Levels during Antiretroviral Therapy Started during Early HIV Infection. Journal of Virology. PMID 26842469 DOI: 10.1128/Jvi.02638-15  0.589
2016 Massanella M, Richman DD. Measuring the latent reservoir in vivo. The Journal of Clinical Investigation. 126: 464-72. PMID 26829625 DOI: 10.1172/Jci80567  0.562
2015 Rokx C, Richman DD, Müller-Trutwin M, Silvestri G, Lunzen J, Khoo S, Lichterfeld M, Altfeld M, Perno CF, Hunt PW, Mallon P, Rockstroh JK, Pozniak AL, Clotet B, Boucher CA. Second European Round Table on the Future Management of HIV: 10-11 October 2014, Barcelona, Spain. Journal of Virus Eradication. 1: 211-20. PMID 27482415 DOI: 10.1016/S2055-6640(20)30497-0  0.591
2015 Massanella M, Gianella S, Lada SM, Richman DD, Strain MC. Quantification of Total and 2-LTR (Long terminal repeat) HIV DNA, HIV RNA and Herpesvirus DNA in PBMCs. Bio-Protocol. 5. PMID 27478862  0.484
2015 Rhee SY, Jordan MR, Raizes E, Chua A, Parkin N, Kantor R, Van Zyl GU, Mukui I, Hosseinipour MC, Frenkel LM, Ndembi N, Hamers RL, Rinke de Wit TF, Wallis CL, Gupta RK, ... ... Richman DD, et al. HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing. Plos One. 10: e0145772. PMID 26717411 DOI: 10.1371/Journal.Pone.0145772  0.443
2015 Wensing AM, Calvez V, Günthard HF, Johnson VA, Paredes R, Pillay D, Shafer RW, Richman DD. 2015 Update of the Drug Resistance Mutations in HIV-1. Topics in Antiviral Medicine. 23: 132-41. PMID 26713503 DOI: 10.5167/Uzh-122257  0.359
2015 Richman DD. HIV: Cure by killing. Nature. 528: 198-9. PMID 26633623 DOI: 10.1038/Nature16321  0.583
2015 Gianella S, Anderson CM, Richman DD, Smith DM, Little SJ. No evidence of posttreatment control after early initiation of antiretroviral therapy. Aids (London, England). 29: 2093-7. PMID 26544575 DOI: 10.1097/Qad.0000000000000816  0.564
2015 Ruggiero A, De Spiegelaere W, Cozzi-Lepri A, Kiselinova M, Pollakis G, Beloukas A, Vandekerckhove L, Strain M, Richman D, Phillips A, Geretti AM. During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ. Ebiomedicine. 2: 1153-9. PMID 26498496 DOI: 10.1016/J.Ebiom.2015.07.025  0.549
2015 Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJ, Miller MD, Hazuda DJ, Deeks SG, et al. A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals. Ebiomedicine. 2: 872-81. PMID 26425694 DOI: 10.1016/J.Ebiom.2015.06.019  0.516
2015 Panichsillapakit T, Smith DM, Wertheim JO, Richman DD, Little SJ, Mehta SR. Prevalence of transmitted HIV drug resistance among recently infected persons in San Diego, California 1996-2013. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 26413846 DOI: 10.1097/Qai.0000000000000831  0.566
2015 White CH, Johnston HE, Moesker B, Manousopoulou A, Margolis DM, Richman DD, Spina CA, Garbis SD, Woelk CH, Beliakova-Bethell N. Mixed effects of suberoylanilide hydroxamic acid (SAHA) on the host transcriptome and proteome and their implications for HIV reactivation from latency. Antiviral Research. 123: 78-85. PMID 26343910 DOI: 10.1016/J.Antiviral.2015.09.002  0.513
2015 Massanella M, Gianella S, Schrier R, Dan JM, Pérez-Santiago J, Oliveira MF, Richman DD, Little SJ, Benson CA, Daar ES, Dube MP, Haubrich RH, Smith DM, Morris SR. Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy. Scientific Reports. 5: 13179. PMID 26299251 DOI: 10.1038/Srep13179  0.527
2015 Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK. Select host restriction factors are associated with HIV persistence during antiretroviral therapy. Aids (London, England). 29: 411-20. PMID 25602681 DOI: 10.1097/Qad.0000000000000572  0.722
2015 Carter CC, Wagner GA, Hightower GK, Caballero G, Phung P, Richman DD, Pond SL, Smith DM. HIV-1 neutralizing antibody response and viral genetic diversity characterized with next generation sequencing. Virology. 474: 34-40. PMID 25463602 DOI: 10.1016/J.Virol.2014.10.019  0.831
2015 Okulicz JF, Le TD, Agan BK, Camargo JF, Landrum ML, Wright E, Dolan MJ, Ganesan A, Ferguson TM, Smith DM, Richman DD, Little SJ, Clark RA, He W, Ahuja SK. Influence of the timing of antiretroviral therapy on the potential for normalization of immune status in human immunodeficiency virus 1-infected individuals. Jama Internal Medicine. 175: 88-99. PMID 25419650 DOI: 10.1001/Jamainternmed.2014.4010  0.523
2015 Woelk CH, White CH, Bosque A, Moesker B, Spina CA, Richman DD, Beliakova-Bethell N, Planelles V. Shining the RNA-Seq microscope on models of HIV latency Journal of Virus Eradication. 1: 1-2. DOI: 10.1016/S2055-6640(20)31278-4  0.488
2015 Rokx C, Richman DD, Müller-Trutwin M, Silvestri G, Lunzen J, Khoo S, Lichterfeld M, Altfeld M, Perno CF, Hunt PW, Mallon P, Rockstroh JK, Pozniak AL, Clotet B, Boucher CA. Second European Round Table on the Future Management of HIV Journal of Virus Eradication. 1: 211-220. DOI: 10.1016/s2055-6640(20)30497-0  0.415
2015 Ruggiero A, De Spiegelaere W, Cozzi-Lepri A, Kiselinova M, Pollakis G, Beloukas A, Vandekerckhove L, Strain M, Richman D, Phillips A, Geretti AM. During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ Ebiomedicine. DOI: 10.1016/j.ebiom.2015.07.025  0.359
2015 Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJO, Miller MD, Hazuda DJ, Deeks SG, et al. A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals Ebiomedicine. DOI: 10.1016/j.ebiom.2015.06.019  0.503
2014 Massanella M, Ouchi D, Marfil S, Llibre JM, Puertas MC, Buzón MJ, Richman DD, Orna E, Stevenson M, Gatell JM, Domingo P, Negredo E, Martinez-Picado J, Clotet B, Blanco J. Different plasma markers of inflammation are influenced by immune recovery and cART composition or intensification in treated HIV infected individuals. Plos One. 9: e114142. PMID 25462535 DOI: 10.1371/Journal.Pone.0114142  0.482
2014 Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG. CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. Plos One. 9: e110731. PMID 25340755 DOI: 10.1371/Journal.Pone.0110731  0.543
2014 Persaud D, Patel K, Karalius B, Rainwater-Lovett K, Ziemniak C, Ellis A, Chen YH, Richman D, Siberry GK, Van Dyke RB, Burchett S, Seage GR, Luzuriaga K. Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents. Jama Pediatrics. 168: 1138-46. PMID 25286283 DOI: 10.1001/Jamapediatrics.2014.1560  0.598
2014 Hepler NL, Scheffler K, Weaver S, Murrell B, Richman DD, Burton DR, Poignard P, Smith DM, Kosakovsky Pond SL. IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. Plos Computational Biology. 10: e1003842. PMID 25254639 DOI: 10.1371/Journal.Pcbi.1003842  0.397
2014 Kim EY, Lorenzo-Redondo R, Little SJ, Chung YS, Phalora PK, Maljkovic Berry I, Archer J, Penugonda S, Fischer W, Richman DD, Bhattacharya T, Malim MH, Wolinsky SM. Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection. Plos Pathogens. 10: e1004281. PMID 25080100 DOI: 10.1371/Journal.Ppat.1004281  0.55
2014 Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK. Decreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapy. The Journal of Infectious Diseases. 210: 1838-43. PMID 24935955 DOI: 10.1093/Infdis/Jiu338  0.714
2014 Luzuriaga K, Tabak B, Garber M, Chen YH, Ziemniak C, McManus MM, Murray D, Strain MC, Richman DD, Chun TW, Cunningham CK, Persaud D. HIV type 1 (HIV-1) proviral reservoirs decay continuously under sustained virologic control in HIV-1-infected children who received early treatment. The Journal of Infectious Diseases. 210: 1529-38. PMID 24850788 DOI: 10.1093/Infdis/Jiu297  0.604
2014 Gianella S, Massanella M, Richman DD, Little SJ, Spina CA, Vargas MV, Lada SM, Daar ES, Dube MP, Haubrich RH, Morris SR, Smith DM. Cytomegalovirus replication in semen is associated with higher levels of proviral HIV DNA and CD4+ T cell activation during antiretroviral treatment. Journal of Virology. 88: 7818-27. PMID 24789781 DOI: 10.1128/Jvi.00831-14  0.605
2014 Archin NM, Bateson R, Tripathy MK, Crooks AM, Yang KH, Dahl NP, Kearney MF, Anderson EM, Coffin JM, Strain MC, Richman DD, Robertson KR, Kashuba AD, Bosch RJ, Hazuda DJ, et al. HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat. The Journal of Infectious Diseases. 210: 728-35. PMID 24620025 DOI: 10.1093/Infdis/Jiu155  0.49
2014 Richman DD. Editorial Commentary: Extending HIV drug resistance testing to low levels of plasma viremia. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: 1174-5. PMID 24429434 DOI: 10.1093/Cid/Ciu025  0.54
2014 Chaillon A, Gianella S, Massanella Luna M, Little SJ, Richman DD, Mehta SR. A case cluster demonstrating the relationship between HLA concordance and virologic and disease outcomes in human immunodeficiency virus infection. Virology. 449: 104-8. PMID 24418543 DOI: 10.1016/J.Virol.2013.11.012  0.407
2014 Tilghman MW, Pérez-Santiago J, Osorio G, Little SJ, Richman DD, Mathews WC, Haubrich RH, Smith DM. Community HIV-1 drug resistance is associated with transmitted drug resistance. Hiv Medicine. 15: 339-46. PMID 24417811 DOI: 10.1111/Hiv.12122  0.443
2014 Karris MY, Kao YT, Patel D, Dawson M, Woods SP, Vaida F, Spina C, Richman D, Little S, Smith DM. Predictors of virologic response in persons who start antiretroviral therapy during recent HIV infection. Aids (London, England). 28: 841-9. PMID 24401640 DOI: 10.1097/Qad.0000000000000149  0.559
2014 Chaillon A, Gianella S, Wertheim JO, Richman DD, Mehta SR, Smith DM. HIV migration between blood and cerebrospinal fluid or semen over time. The Journal of Infectious Diseases. 209: 1642-52. PMID 24302756 DOI: 10.1093/Infdis/Jit678  0.561
2014 Wagner GA, Pacold ME, Kosakovsky Pond SL, Caballero G, Chaillon A, Rudolph AE, Morris SR, Little SJ, Richman DD, Smith DM. Incidence and prevalence of intrasubtype HIV-1 dual infection in at-risk men in the United States. The Journal of Infectious Diseases. 209: 1032-8. PMID 24273040 DOI: 10.1093/Infdis/Jit633  0.814
2014 Tatro ET, Purnajo I, Richman DD, Smith DM, Gianella S. Antibody response to Achromobacter xylosoxidans during HIV infection is associated with lower CD4 levels and increased lymphocyte activation. Clinical and Vaccine Immunology : Cvi. 21: 46-50. PMID 24173027 DOI: 10.1128/Cvi.00553-13  0.589
2014 Wertheim JO, Leigh Brown AJ, Hepler NL, Mehta SR, Richman DD, Smith DM, Kosakovsky Pond SL. The global transmission network of HIV-1. The Journal of Infectious Diseases. 209: 304-13. PMID 24151309 DOI: 10.1093/Infdis/Jit524  0.528
2014 Chaillon A, Gianella S, Vazquez H, Ignacio C, Zweig AC, Richman DD, Smith DM. Novel codon insert in HIV type 1 clade B reverse transcriptase associated with low-level viremia during antiretroviral therapy. Aids Research and Human Retroviruses. 30: 165-9. PMID 24020934 DOI: 10.1089/Aid.2013.0202  0.511
2014 Gianella S, Morris SR, Tatro E, Vargas MV, Haubrich RH, Daar ES, Dube MP, Richman DD, Little SJ, Smith DM. Virologic correlates of anti-CMV IgG levels in HIV-1-infected men. The Journal of Infectious Diseases. 209: 452-6. PMID 23964106 DOI: 10.1093/Infdis/Jit434  0.573
2014 Chung AW, Schoen MK, Robinson H, Licht A, Tkachenko E, Smith DM, Little SJ, Richman DD, Alter G. Polyfunctional Non-neutralizing Fc-antibody Responses in Acute HIV Infection Predict Spontaneous Viral Control Aids Research and Human Retroviruses. 30. DOI: 10.1089/Aid.2014.5162.Abstract  0.519
2013 Pérez-Santiago J, Gianella S, Massanella M, Spina CA, Karris MY, Var SR, Patel D, Jordan PS, Young JA, Little SJ, Richman DD, Smith DM. Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection. Aids (London, England). 27: 1921-31. PMID 24180001 DOI: 10.1097/Qad.0B013E3283611816  0.533
2013 Persaud D, Gay H, Ziemniak C, Chen YH, Piatak M, Chun TW, Strain M, Richman D, Luzuriaga K. Absence of detectable HIV-1 viremia after treatment cessation in an infant. The New England Journal of Medicine. 369: 1828-35. PMID 24152233 DOI: 10.1056/Nejmoa1302976  0.575
2013 Chaillon A, Wagner GA, Hepler NL, Little SJ, Kosakovsky Pond SL, Caballero G, Pacold ME, Phung P, Wrin T, Richman DD, Wertheim JO, Smith DM. Dynamics of viral evolution and neutralizing antibody response after HIV-1 superinfection. Journal of Virology. 87: 12737-44. PMID 24049166 DOI: 10.1128/Jvi.02260-13  0.785
2013 DeBoever C, Reid EG, Smith EN, Wang X, Dumaop W, Harismendy O, Carson D, Richman D, Masliah E, Frazer KA. Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomas. Plos One. 8: e73956. PMID 24023918 DOI: 10.1371/Journal.Pone.0073956  0.429
2013 Hatano H, Strain MC, Scherzer R, Bacchetti P, Wentworth D, Hoh R, Martin JN, McCune JM, Neaton JD, Tracy RP, Hsue PY, Richman DD, Deeks SG. Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial. The Journal of Infectious Diseases. 208: 1436-42. PMID 23975885 DOI: 10.1093/Infdis/Jit453  0.515
2013 Massanella M, Singhania A, Beliakova-Bethell N, Pier R, Lada SM, White CH, Pérez-Santiago J, Blanco J, Richman DD, Little SJ, Woelk CH. Differential gene expression in HIV-infected individuals following ART. Antiviral Research. 100: 420-8. PMID 23933117 DOI: 10.1016/J.Antiviral.2013.07.017  0.48
2013 Hightower GK, May SJ, Pérez-Santiago J, Pacold ME, Wagner GA, Little SJ, Richman DD, Mehta SR, Smith DM, Pond SL. HIV-1 clade B pol evolution following primary infection. Plos One. 8: e68188. PMID 23840830 DOI: 10.1371/Journal.Pone.0068188  0.839
2013 Xu Y, Duggineni S, Espitia S, Richman DD, An J, Huang Z. A synthetic bivalent ligand of CXCR4 inhibits HIV infection. Biochemical and Biophysical Research Communications. 435: 646-50. PMID 23688427 DOI: 10.1016/J.Bbrc.2013.05.038  0.421
2013 Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, ... ... Richman D, et al. Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. Plos Pathogens. 9: e1003347. PMID 23671416 DOI: 10.1371/Journal.Ppat.1003347  0.724
2013 Wagner GA, Pacold ME, Vigil E, Caballero G, Morris SR, Kosakovsky Pond SL, Little SJ, Richman DD, Gianella S, Smith DM. Using ultradeep pyrosequencing to study HIV-1 coreceptor usage in primary and dual infection. The Journal of Infectious Diseases. 208: 271-4. PMID 23599311 DOI: 10.1093/Infdis/Jit168  0.768
2013 Johnson VA, Calvez V, Günthard HF, Paredes R, Pillay D, Shafer RW, Wensing AM, Richman DD. Update of the drug resistance mutations in HIV-1: March 2013 Topics in Antiviral Medicine. 21: 6-14. PMID 23596273  0.388
2013 Gianella S, Smith DM, Vargas MV, Little SJ, Richman DD, Daar ES, Dube MP, Zhang F, Ginocchio CC, Haubrich RH, Morris SR. Shedding of HIV and human herpesviruses in the semen of effectively treated HIV-1-infected men who have sex with men. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 57: 441-7. PMID 23595831 DOI: 10.1093/Cid/Cit252  0.602
2013 Strain MC, Lada SM, Luong T, Rought SE, Gianella S, Terry VH, Spina CA, Woelk CH, Richman DD. Highly precise measurement of HIV DNA by droplet digital PCR. Plos One. 8: e55943. PMID 23573183 DOI: 10.1371/Journal.Pone.0055943  0.539
2013 Rouzioux C, Richman D. How to best measure HIV reservoirs? Current Opinion in Hiv and Aids. 8: 170-5. PMID 23564004 DOI: 10.1097/Coh.0B013E32835Fc619  0.587
2013 Katlama C, Deeks SG, Autran B, Martinez-Picado J, van Lunzen J, Rouzioux C, Miller M, Vella S, Schmitz JE, Ahlers J, Richman DD, Sekaly RP. Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs. Lancet. 381: 2109-17. PMID 23541541 DOI: 10.1016/S0140-6736(13)60104-X  0.59
2013 Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, ... ... Richman DD, et al. Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. Plos Pathogens. 9: e1003174. PMID 23459007 DOI: 10.1371/Journal.Ppat.1003174  0.586
2013 Le T, Wright EJ, Smith DM, He W, Catano G, Okulicz JF, Young JA, Clark RA, Richman DD, Little SJ, Ahuja SK. Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy. The New England Journal of Medicine. 368: 218-30. PMID 23323898 DOI: 10.1056/Nejmoa1110187  0.556
2013 Strain MC, Richman DD. New assays for monitoring residual HIV burden in effectively treated individuals. Current Opinion in Hiv and Aids. 8: 106-10. PMID 23314907 DOI: 10.1097/Coh.0B013E32835D811B  0.5
2013 Wie SH, Du P, Luong TQ, Rought SE, Beliakova-Bethell N, Lozach J, Corbeil J, Kornbluth RS, Richman DD, Woelk CH. HIV downregulates interferon-stimulated genes in primary macrophages. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 90-5. PMID 23276142 DOI: 10.1089/Jir.2012.0052  0.577
2013 Gianella S, Anderson CM, Vargas MV, Richman DD, Little SJ, Morris SR, Smith DM. Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA. The Journal of Infectious Diseases. 207: 898-902. PMID 23275608 DOI: 10.1093/Infdis/Jis777  0.596
2013 Beliakova-Bethell N, Zhang JX, Singhania A, Lee V, Terry VH, Richman DD, Spina CA, Woelk CH. Suberoylanilide hydroxamic acid induces limited changes in the transcriptome of primary CD4(+) T cells. Aids (London, England). 27: 29-37. PMID 23221426 DOI: 10.1097/Qad.0B013E32835B3E26  0.331
2013 Gianella S, Morris SR, Vargas MV, Young JA, Callahan B, Richman DD, Little SJ, Smith DM. Role of seminal shedding of herpesviruses in HIV Type 1 Transmission. The Journal of Infectious Diseases. 207: 257-61. PMID 23148284 DOI: 10.1093/Infdis/Jis683  0.619
2013 Stadeli KM, Richman DD. Rates of emergence of HIV drug resistance in resource-limited settings: a systematic review. Antiviral Therapy. 18: 115-23. PMID 23052978 DOI: 10.3851/Imp2437  0.467
2013 Soto PC, Karris MY, Spina CA, Richman DD, Varki A. Cell-intrinsic mechanism involving Siglec-5 associated with divergent outcomes of HIV-1 infection in human and chimpanzee CD4 T cells. Journal of Molecular Medicine (Berlin, Germany). 91: 261-70. PMID 22945238 DOI: 10.1007/S00109-012-0951-7  0.806
2013 Gianella S, Morris SR, Anderson C, Spina CA, Vargas MV, Young JA, Richman DD, Little SJ, Smith DM. Herpes viruses and HIV-1 drug resistance mutations influence the virologic and immunologic milieu of the male genital tract. Aids (London, England). 27: 39-47. PMID 22739399 DOI: 10.1097/Qad.0B013E3283573305  0.632
2012 Gianella S, Mehta SR, Young JA, Vargas MV, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. Sexual transmission of predicted CXCR4-tropic HIV-1 likely originating from the source partner's seminal cells. Virology. 434: 2-4. PMID 23040890 DOI: 10.1016/J.Virol.2012.09.010  0.421
2012 Hightower GK, Wong JK, Letendre SL, Umlauf AA, Ellis RJ, Ignacio CC, Heaton RK, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, ... ... Richman DD, et al. Higher HIV-1 genetic diversity is associated with AIDS and neuropsychological impairment. Virology. 433: 498-505. PMID 22999095 DOI: 10.1016/J.Virol.2012.08.028  0.832
2012 Gianella S, Mehta SR, Strain MC, Young JA, Vargas MV, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. Impact of seminal cytomegalovirus replication on HIV-1 dynamics between blood and semen. Journal of Medical Virology. 84: 1703-9. PMID 22997072 DOI: 10.1002/Jmv.23398  0.592
2012 Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, Crooks AM, Parker DC, Anderson EM, Kearney MF, Strain MC, Richman DD, Hudgens MG, Bosch RJ, Coffin JM, Eron JJ, et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature. 487: 482-5. PMID 22837004 DOI: 10.1038/Nature11286  0.615
2012 Thompson MA, Aberg JA, Hoy JF, Telenti A, Benson C, Cahn P, Eron JJ, Günthard HF, Hammer SM, Reiss P, Richman DD, Rizzardini G, Thomas DL, Jacobsen DM, Volberding PA. Antiretroviral treatment of adult HIV infection: 2012 recommendations of the International Antiviral Society-USA panel. Jama. 308: 387-402. PMID 22820792 DOI: 10.1001/jama.2012.7961  0.485
2012 Tilghman MW, May S, Pérez-Santiago J, Ignacio CC, Little SJ, Richman DD, Smith DM. A combined screening platform for HIV treatment failure and resistance. Plos One. 7: e35401. PMID 22563383 DOI: 10.1371/Journal.Pone.0035401  0.497
2012 Choi JY, Hightower GK, Wong JK, Heaton R, Woods S, Grant I, Marcotte TD, Ellis RJ, Letendre SL, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, ... ... Richman DD, et al. Genetic features of cerebrospinal fluid-derived subtype B HIV-1 tat. Journal of Neurovirology. 18: 81-90. PMID 22528397 DOI: 10.1007/S13365-011-0059-9  0.847
2012 Mehta SR, Kosakovsky Pond SL, Young JA, Richman D, Little S, Smith DM. Associations between phylogenetic clustering and HLA profile among HIV-infected individuals in San Diego, California. The Journal of Infectious Diseases. 205: 1529-33. PMID 22448013 DOI: 10.1093/Infdis/Jis231  0.411
2012 Agrawal A, DeSoto J, Fullagar JL, Maddali K, Rostami S, Richman DD, Pommier Y, Cohen SM. Probing chelation motifs in HIV integrase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 109: 2251-6. PMID 22308350 DOI: 10.1073/Pnas.1112389109  0.493
2012 Gianella S, Strain MC, Rought SE, Vargas MV, Little SJ, Richman DD, Spina CA, Smith DM. Associations between virologic and immunologic dynamics in blood and in the male genital tract. Journal of Virology. 86: 1307-15. PMID 22114342 DOI: 10.1128/Jvi.06077-11  0.488
2012 Pacold ME, Pond SL, Wagner GA, Delport W, Bourque DL, Richman DD, Little SJ, Smith DM. Clinical, virologic, and immunologic correlates of HIV-1 intraclade B dual infection among men who have sex with men. Aids (London, England). 26: 157-65. PMID 22045341 DOI: 10.1097/Qad.0B013E32834Dcd26  0.814
2012 Richman DD. Contending with the challenges of HIV: A first-hand account Future Virology. 7: 645-648. DOI: 10.2217/fvl.12.50  0.471
2012 Homann S, Smith D, Little S, Richman D, Guatelli J. Upregulation of BST-2/Tetherin by HIV Infection In Vivo Journal of Virology. 86: 13889-13889. DOI: 10.1128/jvi.02451-12  0.521
2012 Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, Crooks AM, Parker DC, Anderson EM, Kearney MF, Strain MC, Richman DD, Hudgens MG, Bosch RJ, Coffin JM, Eron JJ, et al. Erratum: Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy Nature. 489: 460-460. DOI: 10.1038/nature11455  0.439
2011 Johnson VA, Calvez V, Günthard HF, Paredes R, Pillay D, Shafer R, Wensing AM, Richman DD. 2011 update of the drug resistance mutations in HIV-1 Topics in Antiviral Medicine. 19: 156-164. PMID 22156218  0.37
2011 Magee WC, Valiaeva N, Beadle JR, Richman DD, Hostetler KY, Evans DH. Inhibition of HIV-1 by octadecyloxyethyl esters of (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] nucleosides and evaluation of their mechanism of action. Antimicrobial Agents and Chemotherapy. 55: 5063-72. PMID 21896914 DOI: 10.1128/Aac.05161-11  0.534
2011 Homann S, Smith D, Little S, Richman D, Guatelli J. Upregulation of BST-2/Tetherin by HIV infection in vivo. Journal of Virology. 85: 10659-68. PMID 21849457 DOI: 10.1128/Jvi.05524-11  0.617
2011 Gianella S, Delport W, Pacold ME, Young JA, Choi JY, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM. Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants. Journal of Virology. 85: 8359-67. PMID 21632754 DOI: 10.1128/Jvi.02582-10  0.783
2011 Mascolini M, Mellors JW, Richman DD, Boucher CA, Larder BA. HIV and hepatitis virus resistance to antivirals: review of data from the XIX International HIV and Hepatitis Virus Drug Resistance Workshop and curative strategies. Antiviral Therapy. 16: 263-86. PMID 21447877 DOI: 10.3851/Imp1761  0.56
2011 Meditz AL, MaWhinney S, Allshouse A, Feser W, Markowitz M, Little S, Hecht R, Daar ES, Collier AC, Margolick J, Kilby JM, Routy JP, Conway B, Kaldor J, Levy J, ... ... Richman D, et al. Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection. The Journal of Infectious Diseases. 203: 442-51. PMID 21245157 DOI: 10.1093/Infdis/Jiq085  0.548
2011 Richman DD. Introduction: challenges to finding a cure for HIV infection. Current Opinion in Hiv and Aids. 6: 1-3. PMID 21242886 DOI: 10.1097/Coh.0B013E328340Ffa6  0.601
2011 Tilghman MW, Guerena DD, Licea A, Pérez-Santiago J, Richman DD, May S, Smith DM. Pooled nucleic acid testing to detect antiretroviral treatment failure in Mexico. Journal of Acquired Immune Deficiency Syndromes (1999). 56: e70-4. PMID 21124228 DOI: 10.1097/Qai.0B013E3181Ff63D7  0.379
2010 Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, ... ... Richman DD, et al. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science (New York, N.Y.). 330: 1551-7. PMID 21051598 DOI: 10.1126/Science.1195271  0.434
2010 Pacold M, Smith D, Little S, Cheng PM, Jordan P, Ignacio C, Richman D, Pond SK. Comparison of methods to detect HIV dual infection. Aids Research and Human Retroviruses. 26: 1291-8. PMID 20954840 DOI: 10.1089/Aid.2010.0042  0.781
2010 Gianella S, Richman DD. Minority variants of drug-resistant HIV. The Journal of Infectious Diseases. 202: 657-66. PMID 20649427 DOI: 10.1086/655397  0.512
2010 Thompson MA, Aberg JA, Cahn P, Montaner JS, Rizzardini G, Telenti A, Gatell JM, Günthard HF, Hammer SM, Hirsch MS, Jacobsen DM, Reiss P, Richman DD, Volberding PA, Yeni P, et al. Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society-USA panel. Jama. 304: 321-33. PMID 20639566 DOI: 10.1001/Jama.2010.1004  0.476
2010 Morris SR, Little SJ, Cunningham T, Garfein RS, Richman DD, Smith DM. Evaluation of an HIV nucleic acid testing program with automated Internet and voicemail systems to deliver results. Annals of Internal Medicine. 152: 778-85. PMID 20547906 DOI: 10.7326/0003-4819-152-12-201006150-00005  0.556
2010 Manosuthi W, Butler DM, Chantratita W, Sukasem C, Richman DD, Smith DM. Patients infected with HIV type 1 subtype CRF01_AE and failing first-line nevirapine- and efavirenz-based regimens demonstrate considerable cross-resistance to etravirine. Aids Research and Human Retroviruses. 26: 609-11. PMID 20507208 DOI: 10.1089/Aid.2009.0107  0.516
2010 Butler DM, Delport W, Kosakovsky Pond SL, Lakdawala MK, Cheng PM, Little SJ, Richman DD, Smith DM. The origins of sexually transmitted HIV among men who have sex with men. Science Translational Medicine. 2: 18re1. PMID 20371483 DOI: 10.1126/Scitranslmed.3000447  0.486
2010 Markowitz M, Vaida F, Hare CB, Boden D, Mohri H, Hecht FM, Kalayjian RC, Conrad A, Mildvan D, Aberg J, Hogan C, Kilby JM, Balfour HH, Schafer K, Richman D, et al. The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection. The Journal of Infectious Diseases. 201: 1298-302. PMID 20235838 DOI: 10.1086/651664  0.569
2010 Goicoechea M, Jain S, Bi L, Kemper C, Daar ES, Diamond C, Ha B, Flaherty J, Sun S, Richman D, Louie S, Haubrich R. Abacavir and tenofovir disoproxil fumarate co-administration results in a nonadditive antiviral effect in HIV-1-infected patients. Aids (London, England). 24: 707-16. PMID 20087154 DOI: 10.1097/Qad.0B013E32833676Eb  0.552
2010 Manosuthi W, Butler DM, Pérez-Santiago J, Poon AF, Pillai SK, Mehta SR, Pacold ME, Richman DD, Pond SK, Smith DM. Protease polymorphisms in HIV-1 subtype CRF01_AE represent selection by antiretroviral therapy and host immune pressure. Aids (London, England). 24: 411-6. PMID 20009919 DOI: 10.1097/Qad.0B013E3283350Eef  0.768
2010 Poon AF, Swenson LC, Dong WW, Deng W, Kosakovsky Pond SL, Brumme ZL, Mullins JI, Richman DD, Harrigan PR, Frost SD. Phylogenetic analysis of population-based and deep sequencing data to identify coevolving sites in the nef gene of HIV-1. Molecular Biology and Evolution. 27: 819-32. PMID 19955476 DOI: 10.1093/Molbev/Msp289  0.473
2010 Woelk CH, Beliakova-Bethell N, Goicoechea M, Zhao Y, Du P, Rought SE, Lozach J, Pérez-Santiago J, Richman DD, Smith DM, Little SJ. Gene expression before HAART initiation predicts HIV-infected individuals at risk of poor CD4+ T-cell recovery. Aids (London, England). 24: 217-22. PMID 19952713 DOI: 10.1097/Qad.0B013E328334F1F0  0.456
2010 Goicoechea M, Jain S, Bi L, Sun S, Smith G, Ha B, Richman D, Louie S, Haubrich R. Interlaboratory measurement differences in intracellular carbovir triphosphate concentrations in HIV-infected patients: sources of variability in processing, shipping, and quantitation. Journal of Clinical Pharmacology. 50: 968-74. PMID 19952374 DOI: 10.1177/0091270009352186  0.514
2010 MARUYAMA T, UTSUMI K, SATO Y, RICHMAN DD. ChemInform Abstract: Synthesis and Anti-HIV Activity of 2-Substituted 2′-Deoxy-2′- fluoroadenosines. Cheminform. 26: no-no. DOI: 10.1002/chin.199502210  0.382
2009 Johnson VA, Brun-Vezinet F, Clotet B, Gunthard HF, Kuritzkes DR, Pillay D, Schapiro JM, Richman DD. Update of the drug resistance mutations in HIV-1: December 2009. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 17: 138-45. PMID 20068260  0.389
2009 Mascolini M, Boucher CA, Mellors JW, Larder BA, Richman DD. Progress in basic and clinical research on HIV resistance: report on the XVIII International HIV Drug Resistance Workshop. Antiviral Therapy. 14: 1015-37. PMID 19918107 DOI: 10.3851/Imp1423  0.571
2009 Montaner JS, Richman DD, Hammer SM. Poor agreement between 2 assays for measuring low levels of HIV-1 viral load. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 49: 1283-4. PMID 19780662 DOI: 10.1086/605688  0.518
2009 Hightower GK, Letendre SL, Cherner M, Gibson SA, Ellis RJ, Wolfson TJ, Gamst AC, Ignacio CC, Heaton RK, Grant I, Richman DD, Smith DM. Select resistance-associated mutations in blood are associated with lower CSF viral loads and better neuropsychological performance. Virology. 394: 243-8. PMID 19762060 DOI: 10.1016/J.Virol.2009.08.007  0.812
2009 Smith DM, May SJ, Pérez-Santiago J, Strain MC, Ignacio CC, Haubrich RH, Richman DD, Benson CA, Little SJ. The use of pooled viral load testing to identify antiretroviral treatment failure. Aids (London, England). 23: 2151-8. PMID 19730348 DOI: 10.1097/Qad.0B013E3283313Ca9  0.454
2009 Ances BM, Sisti D, Vaida F, Liang CL, Leontiev O, Perthen JE, Buxton RB, Benson D, Smith DM, Little SJ, Richman DD, Moore DJ, Ellis RJ. Resting cerebral blood flow: a potential biomarker of the effects of HIV in the brain. Neurology. 73: 702-8. PMID 19720977 DOI: 10.1212/Wnl.0B013E3181B59A97  0.574
2009 Butler DM, Pacold ME, Jordan PS, Richman DD, Smith DM. The efficiency of single genome amplification and sequencing is improved by quantitation and use of a bioinformatics tool. Journal of Virological Methods. 162: 280-3. PMID 19698751 DOI: 10.1016/J.Jviromet.2009.08.002  0.724
2009 Nugent CT, Dockter J, Bernardin F, Hecht R, Smith D, Delwart E, Pilcher C, Richman D, Busch M, Giachetti C. Detection of HIV-1 in alternative specimen types using the APTIMA HIV-1 RNA Qualitative Assay. Journal of Virological Methods. 159: 10-4. PMID 19442838 DOI: 10.1016/J.Jviromet.2009.02.015  0.554
2009 Jordan PS, Poon A, Eron J, Squires K, Ignacio C, Richman DD, Smith DM. A novel codon insert in protease of clade B HIV type 1. Aids Research and Human Retroviruses. 25: 547-50. PMID 19397401 DOI: 10.1089/Aid.2008.0310  0.56
2009 Eron JJ, Park JG, Haubrich R, Aweeka F, Bastow B, Pakes GE, Yu S, Wu H, Richman DD. Predictive value of pharmacokinetics-adjusted phenotypic susceptibility on response to ritonavir-enhanced protease inhibitors (PIs) in human immunodeficiency virus-infected subjects failing prior PI therapy. Antimicrobial Agents and Chemotherapy. 53: 2335-41. PMID 19307363 DOI: 10.1128/Aac.01387-08  0.482
2009 Yukl S, Pillai S, Li P, Chang K, Pasutti W, Ahlgren C, Havlir D, Strain M, Günthard H, Richman D, Rice AP, Daar E, Little S, Wong JK. Latently-infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity. Virology. 387: 98-108. PMID 19268337 DOI: 10.1016/J.Virol.2009.01.013  0.704
2009 Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, Pomerantz RJ. The challenge of finding a cure for HIV infection. Science (New York, N.Y.). 323: 1304-7. PMID 19265012 DOI: 10.1126/Science.1165706  0.511
2009 Nugent CT, Nodelman V, Giachetti C, Richman DD, Looney DJ. Evaluation of a highly sensitive qualitative human immunodeficiency virus type 1 (HIV-1) RNA assay for detection of HIV-1 suppression. Journal of Clinical Microbiology. 47: 833-6. PMID 19116355 DOI: 10.1128/Jcm.01464-08  0.572
2009 Smith DM, Zárate S, Shao H, Pillai SK, Letendre SL, Wong JK, Richman DD, Frost SD, Ellis RJ. Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations. Virology. 385: 204-8. PMID 19100592 DOI: 10.1016/J.Virol.2008.11.010  0.668
2009 Smith DM, May SJ, Tweeten S, Drumright L, Pacold ME, Kosakovsky Pond SL, Pesano RL, Lie YS, Richman DD, Frost SD, Woelk CH, Little SJ. A public health model for the molecular surveillance of HIV transmission in San Diego, California. Aids (London, England). 23: 225-32. PMID 19098493 DOI: 10.1097/Qad.0B013E32831D2A81  0.758
2009 Binley J, Wrin T, Pantophlet R, Phung P, Crooks E, Lapedes A, Taylor N, Cavacini L, Steigler G, Kunert R, Katinger H, Petropoulos C, Richman D, Morris L, Sutthent R, et al. P04-03. Cross-clade neutralization analysis of plasmas from clade B, C and CRF01_AE HIV-infected donors Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P31  0.4
2008 Hirsch MS, Günthard HF, Schapiro JM, Brun-Vézinet F, Clotet B, Hammer SM, Johnson VA, Kuritzkes DR, Mellors JW, Pillay D, Yeni PG, Jacobsen DM, Richman DD. Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 16: 266-85. PMID 19856548  0.436
2008 Frost SD, Trkola A, Günthard HF, Richman DD. Antibody responses in primary HIV-1 infection. Current Opinion in Hiv and Aids. 3: 45-51. PMID 19372943 DOI: 10.1097/Coh.0B013E3282F310Ae  0.589
2008 Mascolini M, Larder BA, Boucher CA, Richman DD, Mellors JW. Broad advances in understanding HIV resistance to antiretrovirals: report on the XVII International HIV Drug Resistance Workshop. Antiviral Therapy. 13: 1097-113. PMID 19195337  0.351
2008 Binley JM, Lybarger EA, Crooks ET, Seaman MS, Gray E, Davis KL, Decker JM, Wycuff D, Harris L, Hawkins N, Wood B, Nathe C, Richman D, Tomaras GD, Bibollet-Ruche F, et al. Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C. Journal of Virology. 82: 11651-68. PMID 18815292 DOI: 10.1128/Jvi.01762-08  0.462
2008 Precopio ML, Butterfield TR, Casazza JP, Little SJ, Richman DD, Koup RA, Roederer M. Optimizing peptide matrices for identifying T-cell antigens. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 1071-8. PMID 18781655 DOI: 10.1002/Cyto.A.20646  0.351
2008 Hammer SM, Eron JJ, Reiss P, Schooley RT, Thompson MA, Walmsley S, Cahn P, Fischl MA, Gatell JM, Hirsch MS, Jacobsen DM, Montaner JS, Richman DD, Yeni PG, Volberding PA, et al. Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. Jama. 300: 555-70. PMID 18677028 DOI: 10.1001/jama.300.5.555  0.47
2008 Butler DM, Smith DM, Cachay ER, Hightower GK, Nugent CT, Richman DD, Little SJ. Herpes simplex virus 2 serostatus and viral loads of HIV-1 in blood and semen as risk factors for HIV transmission among men who have sex with men. Aids (London, England). 22: 1667-71. PMID 18670228 DOI: 10.1097/Qad.0B013E32830Bfed8  0.834
2008 Grant RM, Hamer D, Hope T, Johnston R, Lange J, Lederman MM, Lieberman J, Miller CJ, Moore JP, Mosier DE, Richman DD, Schooley RT, Springer MS, Veazey RS, Wainberg MA. Whither or wither microbicides? Science (New York, N.Y.). 321: 532-4. PMID 18653884 DOI: 10.1126/Science.1160355  0.357
2008 Hirsch MS, Günthard HF, Schapiro JM, Brun-Vézinet F, Clotet B, Hammer SM, Johnson VA, Kuritzkes DR, Mellors JW, Pillay D, Yeni PG, Jacobsen DM, Richman DD. Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 47: 266-85. PMID 18549313 DOI: 10.1086/589297  0.529
2008 Nelson JD, Kinkead H, Brunel FM, Leaman D, Jensen R, Louis JM, Maruyama T, Bewley CA, Bowdish K, Clore GM, Dawson PE, Frederickson S, Mage RG, Richman DD, Burton DR, et al. Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics. Virology. 377: 170-83. PMID 18499210 DOI: 10.1016/J.Virol.2008.04.005  0.466
2008 Johnson VA, Brun-Vezinet F, Clotet B, Günthard HF, Kuritzkes DR, Pillay D, Schapiro JM, Richman DD. Update of the drug resistance mutations in HIV-1: Spring 2008. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 16: 62-8. PMID 18441382  0.388
2008 Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM. Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance. Aids (London, England). 22: 835-9. PMID 18427201 DOI: 10.1097/Qad.0B013E3282F5Ff71  0.32
2008 Kosakovsky Pond SL, Poon AF, Zárate S, Smith DM, Little SJ, Pillai SK, Ellis RJ, Wong JK, Leigh Brown AJ, Richman DD, Frost SD. Estimating selection pressures on HIV-1 using phylogenetic likelihood models. Statistics in Medicine. 27: 4779-89. PMID 18381707 DOI: 10.1002/Sim.3192  0.717
2008 Ahuja SK, Kulkarni H, Catano G, Agan BK, Camargo JF, He W, O'Connell RJ, Marconi VC, Delmar J, Eron J, Clark RA, Frost S, Martin J, Ahuja SS, Deeks SG, ... ... Richman D, et al. CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals. Nature Medicine. 14: 413-20. PMID 18376407 DOI: 10.1038/Nm1741  0.513
2008 Little SJ, Frost SD, Wong JK, Smith DM, Pond SL, Ignacio CC, Parkin NT, Petropoulos CJ, Richman DD. Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection. Journal of Virology. 82: 5510-8. PMID 18353964 DOI: 10.1128/Jvi.02579-07  0.5
2008 Koelsch KK, Liu L, Haubrich R, May S, Havlir D, Günthard HF, Ignacio CC, Campos-Soto P, Little SJ, Shafer R, Robbins GK, D'Aquila RT, Kawano Y, Young K, Dao P, ... ... Richman DD, et al. Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro. The Journal of Infectious Diseases. 197: 411-9. PMID 18248304 DOI: 10.1086/525283  0.586
2008 Pawlotsky JM, Dusheiko G, Hatzakis A, Lau D, Lau G, Liang TJ, Locarnini S, Martin P, Richman DD, Zoulim F. Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: recommendations for a standardized approach. Gastroenterology. 134: 405-15. PMID 18242209 DOI: 10.1053/J.Gastro.2007.11.036  0.313
2008 Cachay ER, Frost SD, Poon AF, Looney D, Rostami SM, Pacold ME, Richman DD, Little SJ, Smith DM. Herpes simplex virus type 2 acquisition during recent HIV infection does not influence plasma HIV levels. Journal of Acquired Immune Deficiency Syndromes (1999). 47: 592-6. PMID 18197122 DOI: 10.1097/Qai.0B013E318163Bd87  0.832
2007 Richman DD. Advances in the management of HIV-HBV coinfection. Antiviral Therapy. 12: H1. PMID 18284177  0.42
2007 Poon AF, Kosakovsky Pond SL, Richman DD, Frost SD. Mapping protease inhibitor resistance to human immunodeficiency virus type 1 sequence polymorphisms within patients. Journal of Virology. 81: 13598-607. PMID 17913806 DOI: 10.1128/Jvi.01570-07  0.462
2007 Johnson VA, Brun-Vézinet F, Clotet B, Günthard HF, Kuritzkes DR, Pillay D, Schapiro JM, Richman DD. Update of the drug resistance mutations in HIV-1: 2007. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 15: 119-25. PMID 17720996  0.388
2007 Smith DM, Wong JK, Shao H, Hightower GK, Mai SH, Moreno JM, Ignacio CC, Frost SD, Richman DD, Little SJ. Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission. The Journal of Infectious Diseases. 196: 356-60. PMID 17597449 DOI: 10.1086/519164  0.82
2007 Mascolini M, Boucher C, Larder B, Mellors J, Richman D. Key reports from the XV International HIV Drug Resistance Workshop 2006. Antiviral Therapy. 12: 131-45. PMID 17503758  0.357
2007 Dhillon AK, Donners H, Pantophlet R, Johnson WE, Decker JM, Shaw GM, Lee FH, Richman DD, Doms RW, Vanham G, Burton DR. Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors. Journal of Virology. 81: 6548-62. PMID 17409160 DOI: 10.1128/Jvi.02749-06  0.462
2007 Poon AF, Kosakovsky Pond SL, Bennett P, Richman DD, Leigh Brown AJ, Frost SD. Adaptation to human populations is revealed by within-host polymorphisms in HIV-1 and hepatitis C virus. Plos Pathogens. 3: e45. PMID 17397261 DOI: 10.1371/Journal.Ppat.0030045  0.436
2007 Cachay ER, Frost SD, Richman DD, Smith DM, Little SJ. Herpes simplex virus type 2 infection does not influence viral dynamics during early HIV-1 infection. The Journal of Infectious Diseases. 195: 1270-7. PMID 17396995 DOI: 10.1086/513568  0.618
2007 Noviello CM, Pond SL, Lewis MJ, Richman DD, Pillai SK, Yang OO, Little SJ, Smith DM, Guatelli JC. Maintenance of Nef-mediated modulation of major histocompatibility complex class I and CD4 after sexual transmission of human immunodeficiency virus type 1. Journal of Virology. 81: 4776-86. PMID 17329339 DOI: 10.1128/Jvi.01793-06  0.593
2007 Smith D, Moini N, Pesano R, Cachay E, Aiem H, Lie Y, Richman D, Little S. Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 44: 456-8. PMID 17205459 DOI: 10.1086/510748  0.551
2007 Boucher C, Larder B, Mellors J, Richman D. The XIVth International HIV Drug Resistance Workshop, Quebec City, Canada, June 2005. Antiviral Therapy. 11: 653-65. PMID 16964836  0.409
2007 Richman DD, Wasserman R, Locarnini SA. Antiviral drug resistance: Implications for treatment of HBV infection and similarities with HIV disease Gastroenterology and Hepatology. 3: 15-22.  0.384
2006 Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, ... ... Richman DD, et al. A plea for justice for jailed medical workers. Science (New York, N.Y.). 314: 924-5. PMID 17062652 DOI: 10.1126/Science.1136578  0.317
2006 Hammer SM, Saag MS, Schechter M, Montaner JS, Schooley RT, Jacobsen DM, Thompson MA, Carpenter CC, Fischl MA, Gazzard BG, Gatell JM, Hirsch MS, Katzenstein DA, Richman DD, Vella S, et al. Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society--USA panel. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 14: 827-43. PMID 17016878  0.347
2006 Smith DM, Strain MC, Frost SD, Pillai SK, Wong JK, Wrin T, Liu Y, Petropolous CJ, Daar ES, Little SJ, Richman DD. Lack of neutralizing antibody response to HIV-1 predisposes to superinfection. Virology. 355: 1-5. PMID 16962152 DOI: 10.1016/J.Virol.2006.08.009  0.685
2006 Hammer SM, Saag MS, Schechter M, Montaner JS, Schooley RT, Jacobsen DM, Thompson MA, Carpenter CC, Fischl MA, Gazzard BG, Gatell JM, Hirsch MS, Katzenstein DA, Richman DD, Vella S, et al. Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel. Jama. 296: 827-43. PMID 16905788 DOI: 10.1001/Jama.296.7.827  0.378
2006 Day JR, Martínez LE, Sásik R, Hitchin DL, Dueck ME, Richman DD, Guatelli JC. A computer-based, image-analysis method to quantify HIV-1 infection in a single-cycle infectious center assay. Journal of Virological Methods. 137: 125-33. PMID 16876264 DOI: 10.1016/J.Jviromet.2006.06.019  0.554
2006 Pond SL, Frost SD, Grossman Z, Gravenor MB, Richman DD, Brown AJ. Adaptation to different human populations by HIV-1 revealed by codon-based analyses. Plos Computational Biology. 2: e62. PMID 16789820 DOI: 10.1371/Journal.Pcbi.0020062  0.402
2006 Pillai SK, Pond SL, Liu Y, Good BM, Strain MC, Ellis RJ, Letendre S, Smith DM, Günthard HF, Grant I, Marcotte TD, McCutchan JA, Richman DD, Wong JK. Genetic attributes of cerebrospinal fluid-derived HIV-1 env. Brain : a Journal of Neurology. 129: 1872-83. PMID 16735456 DOI: 10.1093/Brain/Awl136  0.706
2006 Richman DD. Antiviral drug resistance. Antiviral Research. 71: 117-21. PMID 16621040 DOI: 10.1016/J.Antiviral.2006.03.004  0.348
2006 Yuste E, Sanford HB, Carmody J, Bixby J, Little S, Zwick MB, Greenough T, Burton DR, Richman DD, Desrosiers RC, Johnson WE. Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma. Journal of Virology. 80: 3030-41. PMID 16501112 DOI: 10.1128/Jvi.80.6.3030-3041.2006  0.531
2006 Kumar S, Choi WT, Dong CZ, Madani N, Tian S, Liu D, Wang Y, Pesavento J, Wang J, Fan X, Yuan J, Fritzsche WR, An J, Sodroski JG, Richman DD, et al. SMM-chemokines: A class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development Chemistry and Biology. 13: 69-79. PMID 16426973 DOI: 10.1016/J.Chembiol.2005.10.012  0.365
2005 Crooks ET, Moore PL, Richman D, Robinson J, Crooks JA, Franti M, Schülke N, Binley JM. Characterizing anti-HIV monoclonal antibodies and immune sera by defining the mechanism of neutralization. Human Antibodies. 14: 101-13. PMID 16720980 DOI: 10.3233/Hab-2005-143-407  0.437
2005 Frost SD, Wrin T, Smith DM, Kosakovsky Pond SL, Liu Y, Paxinos E, Chappey C, Galovich J, Beauchaine J, Petropoulos CJ, Little SJ, Richman DD. Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection. Proceedings of the National Academy of Sciences of the United States of America. 102: 18514-9. PMID 16339909 DOI: 10.1073/Pnas.0504658102  0.549
2005 Lehrman G, Hogue IB, Palmer S, Jennings C, Spina CA, Wiegand A, Landay AL, Coombs RW, Richman DD, Mellors JW, Coffin JM, Bosch RJ, Margolis DM. Depletion of latent HIV-1 infection in vivo: a proof-of-concept study. Lancet. 366: 549-55. PMID 16099290 DOI: 10.1016/S0140-6736(05)67098-5  0.564
2005 Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Petropoulos CJ, Richman DD, Little SJ. HIV drug resistance acquired through superinfection. Aids (London, England). 19: 1251-6. PMID 16052079 DOI: 10.1097/01.Aids.0000180095.12276.Ac  0.827
2005 Smith DM, Richman DD, Little SJ. HIV superinfection Journal of Infectious Diseases. 192: 438-444. PMID 15995957 DOI: 10.1086/431682  0.485
2005 Zolopa AR, Lazzeroni LC, Rinehart A, Vezinet FB, Clavel F, Collier A, Conway B, Gulick RM, Holodniy M, Perno CF, Shafer RW, Richman DD, Wainberg MA, Kuritzkes DR. Accuracy, precision, and consistency of expert HIV type 1 genotype interpretation: an international comparison (The GUESS Study). Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 41: 92-9. PMID 15937768 DOI: 10.1086/430706  0.487
2005 Daar ES, Richman DD. Confronting the emergence of drug-resistant HIV type 1: Impact of antiretroviral therapy on individual and population resistance Aids Research and Human Retroviruses. 21: 343-357. PMID 15929696 DOI: 10.1089/Aid.2005.21.343  0.43
2005 Pillai SK, Kosakovsky Pond SL, Woelk CH, Richman DD, Smith DM. Codon volatility does not reflect selective pressure on the HIV-1 genome. Virology. 336: 137-43. PMID 15892955 DOI: 10.1016/J.Virol.2005.03.014  0.644
2005 Frost SD, Liu Y, Pond SL, Chappey C, Wrin T, Petropoulos CJ, Little SJ, Richman DD. Characterization of human immunodeficiency virus type 1 (HIV-1) envelope variation and neutralizing antibody responses during transmission of HIV-1 subtype B. Journal of Virology. 79: 6523-7. PMID 15858036 DOI: 10.1128/Jvi.79.10.6523-6527.2005  0.598
2005 Strain MC, Little SJ, Daar ES, Havlir DV, Gunthard HF, Lam RY, Daly OA, Nguyen J, Ignacio CC, Spina CA, Richman DD, Wong JK. Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. The Journal of Infectious Diseases. 191: 1410-8. PMID 15809898 DOI: 10.1086/428777  0.571
2005 Strain MC, Letendre S, Pillai SK, Russell T, Ignacio CC, Günthard HF, Good B, Smith DM, Wolinsky SM, Furtado M, Marquie-Beck J, Durelle J, Grant I, Richman DD, Marcotte T, et al. Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy. Journal of Virology. 79: 1772-88. PMID 15650202 DOI: 10.1128/Jvi.79.3.1772-1788.2005  0.734
2005 Pillai SK, Good B, Pond SK, Wong JK, Strain MC, Richman DD, Smith DM. Semen-specific genetic characteristics of human immunodeficiency virus type 1 env. Journal of Virology. 79: 1734-42. PMID 15650198 DOI: 10.1128/Jvi.79.3.1734-1742.2005  0.678
2005 Yang OO, Daar ES, Jamieson BD, Balamurugan A, Smith DM, Pitt JA, Petropoulos CJ, Richman DD, Little SJ, Brown AJ. Human immunodeficiency virus type 1 clade B superinfection: evidence for differential immune containment of distinct clade B strains. Journal of Virology. 79: 860-8. PMID 15613314 DOI: 10.1128/Jvi.79.2.860-868.2005  0.536
2005 Woelk CH, Ottones F, Plotkin CR, Du P, Royer CD, Rought SE, Lozach J, Sasik R, Kornbluth RS, Richman DD, Corbeil J. Interferon gene expression following HIV type 1 infection of monocyte-derived macrophages. Aids Research and Human Retroviruses. 20: 1210-22. PMID 15588343 DOI: 10.1089/Aid.2004.20.1210  0.471
2004 Richman DD, Little SJ, Smith DM, Wrin T, Petropoulos C, Wong JK. HIV evolution and escape. Transactions of the American Clinical and Climatological Association. 115: 289-303. PMID 17060974  0.479
2004 Dong T, Stewart-Jones G, Chen N, Easterbrook P, Xu X, Papagno L, Appay V, Weekes M, Conlon C, Spina C, Little S, Screaton G, van der Merwe A, Richman DD, McMichael AJ, et al. HIV-specific cytotoxic T cells from long-term survivors select a unique T cell receptor. The Journal of Experimental Medicine. 200: 1547-57. PMID 15596521 DOI: 10.1084/Jem.20032044  0.521
2004 Johnson VA, Brun-Vézinet F, Clotet B, Conway B, D'Aquila RT, Demeter LM, Kuritzkes DR, Pillay D, Schapiro JM, Telenti A, Richman DD. Update of the drug resistance mutations in HIV-1: 2004. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 12: 119-24. PMID 15516709  0.388
2004 Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Daar ES, Richman DD, Little SJ. Incidence of HIV superinfection following primary infection. Jama. 292: 1177-8. PMID 15353529 DOI: 10.1001/Jama.292.10.1177  0.847
2004 Yeni PG, Hammer SM, Hirsch MS, Saag MS, Schechter M, Carpenter CC, Fischl MA, Gatell JM, Gazzard BG, Jacobsen DM, Katzenstein DA, Montaner JS, Richman DD, Schooley RT, Thompson MA, et al. Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel. Jama. 292: 251-65. PMID 15249575 DOI: 10.1001/Jama.292.2.251  0.535
2004 Smith DM, Kingery JD, Wong JK, Ignacio CC, Richman DD, Little SJ. The prostate as a reservoir for HIV-1. Aids (London, England). 18: 1600-2. PMID 15238781 DOI: 10.1097/01.Aids.0000131364.60081.01  0.515
2004 Richman DD, Morton SC, Wrin T, Hellmann N, Berry S, Shapiro MF, Bozzette SA. The prevalence of antiretroviral drug resistance in the United States. Aids (London, England). 18: 1393-401. PMID 15199315 DOI: 10.1097/01.Aids.0000131310.52526.C7  0.59
2004 Yu Q, König R, Pillai S, Chiles K, Kearney M, Palmer S, Richman D, Coffin JM, Landau NR. Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome. Nature Structural & Molecular Biology. 11: 435-42. PMID 15098018 DOI: 10.1038/Nsmb758  0.662
2004 Richman DD. Benefits and limitations of testing for resistance to HIV drugs Journal of Antimicrobial Chemotherapy. 53: 555-557. PMID 15014064 DOI: 10.1093/Jac/Dkh157  0.498
2004 Papagno L, Spina CA, Marchant A, Salio M, Rufer N, Little S, Dong T, Chesney G, Waters A, Easterbrook P, Dunbar PR, Shepherd D, Cerundolo V, Emery V, Griffiths P, ... ... Richman DD, et al. Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection. Plos Biology. 2: E20. PMID 14966528 DOI: 10.1371/Journal.Pbio.0020020  0.554
2004 Leigh Brown AJ, Frost SD, Good B, Daar ES, Simon V, Markowitz M, Collier AC, Connick E, Conway B, Margolick JB, Routy JP, Corbeil J, Hellmann NS, Richman DD, Little SJ. Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection. Journal of Virology. 78: 2242-6. PMID 14963120 DOI: 10.1128/Jvi.78.5.2242-2246.2004  0.588
2004 Burton DR, Desrosiers RC, Doms RW, Feinberg MB, Gallo RC, Hahn B, Hoxie JA, Hunter E, Korber B, Landay A, Lederman MM, Lieberman J, McCune JM, Moore JP, Nathanson N, ... ... Richman D, et al. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science (New York, N.Y.). 303: 316. PMID 14726576 DOI: 10.1126/Science.1094620  0.334
2003 Johnson VA, Brun-Vézinet F, Clotet B, Conway B, D'Aquila RT, Demeter LM, Kuritzkes DR, Pillay D, Schapiro JM, Telenti A, Richman DD. Drug resistance mutations in HIV-1. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 11: 215-21. PMID 14724329  0.329
2003 Haas DW, Wilkinson GR, Kuritzkes DR, Richman DD, Nicotera J, Mahon LF, Sutcliffe C, Siminski S, Andersen J, Coughlin K, Clayton EW, Haines J, Marshak A, Saag M, Lawrence J, et al. A multi-investigator/institutional DNA bank for AIDS-related human genetic studies: AACTG Protocol A5128. Hiv Clinical Trials. 4: 287-300. PMID 14583845 DOI: 10.1310/Muqc-Qxbc-8118-Bpm5  0.418
2003 Gulick RM, Meibohm A, Havlir D, Eron JJ, Mosley A, Chodakewitz JA, Isaacs R, Gonzalez C, McMahon D, Richman DD, Robertson M, Mellors JW. Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine Aids. 17: 2345-2349. PMID 14571186 DOI: 10.1097/00002030-200311070-00009  0.536
2003 Ali A, Pillai S, Ng H, Lubong R, Richman DD, Jamieson BD, Ding Y, McElrath MJ, Guatelli JC, Yang OO. Broadly increased sensitivity to cytotoxic T lymphocytes resulting from Nef epitope escape mutations. Journal of Immunology (Baltimore, Md. : 1950). 171: 3999-4005. PMID 14530319 DOI: 10.4049/Jimmunol.171.8.3999  0.644
2003 Hirsch MS, Brun-Vézinet F, Clotet B, Conway B, Kuritzkes DR, D'Aquila RT, Demeter LM, Hammer SM, Johnson VA, Loveday C, Mellors JW, Richman DD. Questions to and answers from the International AIDS Society-USA Resistance Testing Guidelines Panel. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 11: 150-4. PMID 12876334  0.322
2003 D'Aquila RT, Schapiro JM, Brun-Vézinet F, Clotet B, Conway B, Demeter LM, Grant RM, Johnson VA, Kuritzkes DR, Loveday C, Shafer RW, Richman DD. Drug resistance mutations in HIV-1. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 11: 92-6. PMID 12837968  0.388
2003 Hirsch MS, Brun-Vézinet F, Clotet B, Conway B, Kuritzkes DR, D'Aquila RT, Demeter LM, Hammer SM, Johnson VA, Loveday C, Mellors JW, Jacobsen DM, Richman DD. Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 37: 113-28. PMID 12830416 DOI: 10.1086/375597  0.57
2003 Zaunders JJ, Moutouh-de Parseval L, Kitada S, Reed JC, Rought S, Genini D, Leoni L, Kelleher A, Cooper DA, Smith DE, Grey P, Estaquier J, Little S, Richman DD, Corbeil J. Polyclonal proliferation and apoptosis of CCR5+ T lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2. The Journal of Infectious Diseases. 187: 1735-47. PMID 12751031 DOI: 10.1086/375030  0.387
2003 Koelsch KK, Smith DM, Little SJ, Ignacio CC, Macaranas TR, Leigh Brown AJ, Petropoulos CJ, Richman DD, Wong JK. Clade B HIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus Aids. 17: F11-F16. PMID 12700477 DOI: 10.1097/00002030-200305020-00001  0.62
2003 Strain MC, Günthard HF, Havlir DV, Ignacio CC, Smith DM, Leigh-Brown AJ, Macaranas TR, Lam RY, Daly OA, Fischer M, Opravil M, Levine H, Bacheler L, Spina CA, Richman DD, et al. Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence. Proceedings of the National Academy of Sciences of the United States of America. 100: 4819-24. PMID 12684537 DOI: 10.1073/Pnas.0736332100  0.605
2003 Richman DD, Wrin T, Little SJ, Petropoulos CJ. Rapid evolution of the neutralizing antibody response to HIV type 1 infection Proceedings of the National Academy of Sciences of the United States of America. 100: 4144-4149. PMID 12644702 DOI: 10.1073/Pnas.0630530100  0.529
2003 Pillai S, Good B, Richman D, Corbeil J. A new perspective on V3 phenotype prediction. Aids Research and Human Retroviruses. 19: 145-9. PMID 12643277 DOI: 10.1089/088922203762688658  0.616
2003 Sheeter D, Du P, Rought S, Richman D, Corbeil J. Surface CD4 expression modulated by a cellular factor induced by HIV type 1 infection. Aids Research and Human Retroviruses. 19: 117-123. PMID 12639247 DOI: 10.1089/088922203762688621  0.839
2003 Leigh Brown AJ, Frost SD, Mathews WC, Dawson K, Hellmann NS, Daar ES, Richman DD, Little SJ. Transmission fitness of drug-resistant human immunodeficiency virus and the prevalence of resistance in the antiretroviral-treated population. The Journal of Infectious Diseases. 187: 683-6. PMID 12599087 DOI: 10.1086/367989  0.481
2003 Anton PA, Mitsuyasu RT, Deeks SG, Scadden DT, Wagner B, Huang C, Macken C, Richman DD, Christopherson C, Borellini F, Lazar R, Hege KM. Multiple measures of HIV burden in blood and tissue are correlated with each other but not with clinical parameters in aviremic subjects Aids. 17: 53-63. PMID 12478069 DOI: 10.1097/00002030-200301030-00008  0.588
2003 Pillai S, Good B, Richman D, Corbeil J. Sequence Note: A New Perspective on V3 Phenotype Prediction Aids Research and Human Retroviruses. 19: 347-347. DOI: 10.1089/088922203764969564  0.477
2002 D'Aquila RT, Schapiro JM, Brun-Vézinet F, Clotet B, Conway B, Demeter LM, Grant RM, Johnson VA, Kuritzkes DR, Loveday C, Shafer RW, Richman DD. Drug Resistance Mutations in HIV-1. Topics in Hiv Medicine : a Publication of the International Aids Society, Usa. 10: 21-25. PMID 12717052  0.388
2002 Uckun FM, Pendergrass S, Venkatachalam TK, Qazi S, Richman D. Stampidine is a potent inhibitor of Zidovudine- and nucleoside analog reverse transcriptase inhibitor-resistant primary clinical human immunodeficiency virus type 1 isolates with thymidine analog mutations. Antimicrobial Agents and Chemotherapy. 46: 3613-6. PMID 12384373 DOI: 10.1128/Aac.46.11.3613-3616.2002  0.526
2002 Bennett KK, DeGruttola VG, Marschner IC, Havlir DV, Richman DD. Baseline predictors of CD4 T-lymphocyte recovery with combination antiretroviral therapy Journal of Acquired Immune Deficiency Syndromes. 31: 20-26. PMID 12352146 DOI: 10.1097/00126334-200209010-00003  0.47
2002 Strain MC, Richman DD, Wong JK, Levine H. Spatiotemporal dynamics of HIV propagation. Journal of Theoretical Biology. 218: 85-96. PMID 12297072 DOI: 10.1006/Jtbi.2002.3055  0.494
2002 Little SJ, Holte S, Routy JP, Daar ES, Markowitz M, Collier AC, Koup RA, Mellors JW, Connick E, Conway B, Kilby M, Wang L, Whitcomb JM, Hellmann NS, Richman DD. Antiretroviral-drug resistance among patients recently infected with HIV. The New England Journal of Medicine. 347: 385-94. PMID 12167680 DOI: 10.1056/Nejmoa013552  0.586
2002 Pollard RB, Tierney C, Havlir D, Tebas P, Fox L, Smeaton L, Richman D, Friedland GH. A phase II randomized study of the virologic and immunologic effect of zidovudine + stavudine versus stavudine alone and zidovudine + lamivudine in patients with >300 CD4 cells who were antiretroviral naive (ACTG 298). Aids Research and Human Retroviruses. 18: 699-704. PMID 12167276 DOI: 10.1089/088922202760072311  0.438
2002 Yeni PG, Hammer SM, Carpenter CC, Cooper DA, Fischl MA, Gatell JM, Gazzard BG, Hirsch MS, Jacobsen DM, Katzenstein DA, Montaner JS, Richman DD, Saag MS, Schechter M, Schooley RT, et al. Antiretroviral treatment for adult HIV infection in 2002: updated recommendations of the International AIDS Society-USA Panel. Jama. 288: 222-35. PMID 12095387 DOI: 10.1001/Jama.288.2.222  0.501
2002 Deeks SG, Wagner B, Anton PA, Mitsuyasu RT, Scadden DT, Huang C, Macken C, Richman DD, Christopherson C, June CH, Lazar R, Broad DF, Jalali S, Hege KM. A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy Molecular Therapy. 5: 788-797. PMID 12027564 DOI: 10.1006/Mthe.2002.0611  0.575
2002 Estaquier J, Lelièvre JD, Petit F, Brunner T, Moutouh-De Parseval L, Richman DD, Ameisen JC, Corbeil J. Effects of antiretroviral drugs on human immunodeficiency virus type 1-induced CD4(+) T-cell death. Journal of Virology. 76: 5966-73. PMID 12021329 DOI: 10.1128/Jvi.76.12.5966-5973.2002  0.49
2002 Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GM, Papagno L, Ogg GS, King A, Lechner F, Spina CA, Little S, Havlir DV, Richman DD, Gruener N, Pape G, et al. Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nature Medicine. 8: 379-85. PMID 11927944 DOI: 10.1038/Nm0402-379  0.455
2002 Appay V, Papagno L, Spina CA, Hansasuta P, King A, Jones L, Ogg GS, Little S, McMichael AJ, Richman DD, Rowland-Jones SL. Dynamics of T cell responses in HIV infection. Journal of Immunology (Baltimore, Md. : 1950). 168: 3660-6. PMID 11907132 DOI: 10.4049/Jimmunol.168.7.3660  0.507
2002 Appay V, Hansasuta P, Sutton J, Schrier RD, Wong JK, Furtado M, Havlir DV, Wolinsky SM, McMichael AJ, Richman DD, Rowland-Jones SL, Spina CA. Persistent HIV-1-specific cellular responses despite prolonged therapeutic viral suppression. Aids (London, England). 16: 161-70. PMID 11807299 DOI: 10.1097/00002030-200201250-00004  0.607
2002 Casimiro DR, Tang A, Perry HC, Long RS, Chen M, Heidecker GJ, Davies ME, Freed DC, Persaud NV, Dubey S, Smith JG, Havlir D, Richman D, Chastain MA, Simon AJ, et al. Vaccine-induced immune responses in rodents and nonhuman primates by use of a humanized human immunodeficiency virus type 1 pol gene. Journal of Virology. 76: 185-94. PMID 11739684 DOI: 10.1128/Jvi.76.1.185-194.2002  0.485
2002 Appay V, Papagno L, Spina CA, Hansasuta P, King A, Jones L, Ogg GS, Little S, McMichael AJ, Richman DD, Rowland-Jones SL. Dynamics of T Cell Responses in HIV Infection The Journal of Immunology. 169: 607.2-607. DOI: 10.4049/jimmunol.169.1.607-a  0.453
2001 Richman DD, Johnson VA, Mayers DM, Shirasaka T, O'Brien MC, Mitsuya H. In vitro evaluation of experimental agents for anti-HIV activity. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 12.9. PMID 18432713 DOI: 10.1002/0471142735.Im1209S08  0.529
2001 Douek DC, Betts MR, Hill BJ, Little SJ, Lempicki R, Metcalf JA, Casazza J, Yoder C, Adelsberger JW, Stevens RA, Baseler MW, Keiser P, Richman DD, Davey RT, Koup RA. Evidence for increased T cell turnover and decreased thymic output in HIV infection Journal of Immunology. 167: 6663-6668. PMID 11714838 DOI: 10.4049/Jimmunol.167.11.6663  0.582
2001 Bühler B, Lin Y, Morris G, Olson AJ, Wong C, Richman DD, Elder JH, Torbett BE. Viral evolution in response to the broad-based retroviral protease inhibitor TL-3 Journal of Virology. 75: 9502-9508. PMID 11533212 DOI: 10.1128/Jvi.75.19.9502-9508.2001  0.346
2001 Havlir DV, Gilbert PB, Bennett K, Collier AC, Hirsch MS, Tebas P, Adams EM, Wheat LJ, Goodwin D, Schnittman S, Holohan MK, Richman DD. Effects of treatment intensification with hydroxyurea in HIV-infected patients with virologic suppression. Aids (London, England). 15: 1379-88. PMID 11504959 DOI: 10.1097/00002030-200107270-00007  0.557
2001 Horner AA, Datta SK, Takabayashi K, Belyakov IM, Hayashi T, Cinman N, Nguyen MD, Van Uden JH, Berzofsky JA, Richman DD, Raz E. Immunostimulatory DNA-based vaccines elicit multifaceted immune responses against HIV at systemic and mucosal sites. Journal of Immunology (Baltimore, Md. : 1950). 167: 1584-91. PMID 11466380 DOI: 10.4049/Jimmunol.167.3.1584  0.443
2001 Hale P, Makgoba MW, Merson MH, Quinn TC, Richman DD, Vella S, Wabwire-Mangen F, Wain-Hobson S, Weiss RA. Mission now possible for AIDS fund. Nature. 412: 271-2. PMID 11460133 DOI: 10.1038/35085650  0.336
2001 Havlir DV, Bassett R, Levitan D, Gilbert P, Tebas P, Collier AC, Hirsch MS, Ignacio C, Condra J, Günthard HF, Richman DD, Wong JK. Prevalence and predictive value of intermittent viremia with combination hiv therapy. Jama. 286: 171-9. PMID 11448280 DOI: 10.1001/Jama.286.2.171  0.474
2001 Corbeil J, Sheeter D, Genini D, Rought S, Leoni L, Du P, Ferguson M, Masys DR, Welsh JB, Fink JL, Sasik R, Huang D, Drenkow J, Richman DD, Gingeras T. Temporal gene regulation during HIV-1 infection of human CD4+ T cells. Genome Research. 11: 1198-204. PMID 11435401 DOI: 10.1101/Gr.180201  0.82
2001 Frost SD, Günthard HF, Wong JK, Havlir D, Richman DD, Leigh Brown AJ. Evidence for positive selection driving the evolution of HIV-1 env under potent antiviral therapy. Virology. 284: 250-8. PMID 11384224 DOI: 10.1006/Viro.2000.0887  0.549
2001 Hammond JL, Koontz DL, Bazmi HZ, Beadle JR, Hostetler SE, Kini GD, Aldern KA, Richman DD, Hostetler KY, Mellors JW. Alkylglycerol prodrugs of phosphonoformate are potent in vitro inhibitors of nucleoside-resistant human immunodeficiency virus type 1 and select for resistance mutations that suppress zidovudine resistance. Antimicrobial Agents and Chemotherapy. 45: 1621-8. PMID 11353603 DOI: 10.1128/Aac.45.6.1621-1628.2001  0.47
2001 Huang W, De Gruttola V, Fischl M, Hammer S, Richman D, Havlir D, Gulick R, Squires K, Mellors J. Patterns of plasma human immunodeficiency virus type 1 RNA response to antiretroviral therapy. The Journal of Infectious Diseases. 183: 1455-65. PMID 11319681 DOI: 10.1086/320192  0.53
2001 Kemper CA, Witt MD, Keiser PH, Dubé MP, Forthal DN, Leibowitz M, Smith DS, Rigby A, Hellmann NS, Lie YS, Leedom J, Richman D, McCutchan JA, Haubrich R. Sequencing of protease inhibitor therapy: insights from an analysis of HIV phenotypic resistance in patients failing protease inhibitors. Aids (London, England). 15: 609-15. PMID 11316998 DOI: 10.1097/00002030-200103300-00010  0.481
2001 Richman DD. HIV chemotherapy Nature. 410: 995-1001. PMID 11309630 DOI: 10.1038/35073673  0.517
2001 Günthard HF, Havlir DV, Fiscus S, Zhang ZQ, Eron J, Mellors J, Gulick R, Frost SD, Brown AJ, Schleif W, Valentine F, Jonas L, Meibohm A, Ignacio CC, Isaacs R, ... ... Richman DD, et al. Residual human immunodeficiency virus (HIV) Type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal fluid after suppression of viremia for 2 years. The Journal of Infectious Diseases. 183: 1318-27. PMID 11294662 DOI: 10.1086/319864  0.547
2001 Stuyver LJ, Locarnini SA, Lok A, Richman DD, Carman WF, Dienstag JL, Schinazi RF, Bartholomeusz A, Di Bisceglie A, De Man RA, Dusheiko G, Furman PA, La Colla P, Lai CL, Lau JYN, et al. Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region Hepatology. 33: 751-757. PMID 11230757 DOI: 10.1053/Jhep.2001.22166  0.344
2001 Daar ES, Little S, Pitt J, Santangelo J, Ho P, Harawa N, Kerndt P, Glorgi JV, Bai J, Gaut P, Richman DD, Mandel S, Nichols S. Diagnosis of primary HIV-1 infection. Los Angeles County Primary HIV Infection Recruitment Network. Annals of Internal Medicine. 134: 25-9. PMID 11187417 DOI: 10.7326/0003-4819-134-1-200101020-00010  0.583
2001 Schacker T, Little S, Connick E, Gebhard K, Zhang ZQ, Krieger J, Pryor J, Havlir D, Wong JK, Schooley RT, Richman D, Corey L, Haase AT. Productive infection of T cells in lymphoid tissues during primary and early human immunodeficiency virus infection. The Journal of Infectious Diseases. 183: 555-62. PMID 11170980 DOI: 10.1086/318524  0.472
2001 Genini D, Sheeter D, Rought S, Zaunders JJ, Susin SA, Kroemer G, Richman DD, Carson DA, Corbeil J, Leoni LM. HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 5-6. PMID 11099484 DOI: 10.1096/Fj.00-0336Fje  0.843
2000 Zhou XJ, Havlir DV, Richman DD, Acosta EP, Hirsch M, Collier AC, Tebas P, Sommadossi JP. Plasma population pharmacokinetics and penetration into cerebrospinal fluid of indinavir in combination with zidovudine and lamivudine in HIV-1-infected patients. Aids (London, England). 14: 2869-76. PMID 11153668 DOI: 10.1097/00002030-200012220-00008  0.377
2000 Leigh Brown AJ, Precious HM, Whitcomb JM, Wong JK, Quigg M, Huang W, Daar ES, D'Aquila RT, Keiser PH, Connick E, Hellmann NS, Petropoulos CJ, Richman DD, Little SJ. Reduced susceptibility of human immunodeficiency virus type 1 (HIV-1) from patients with primary HIV infection to nonnucleoside reverse transcriptase inhibitors is associated with variation at novel amino acid sites Journal of Virology. 74: 10269-10273. PMID 11044070 DOI: 10.1128/Jvi.74.22.10269-10273.2000  0.529
2000 Gilbert PB, Hanna GJ, De Gruttola V, Martinez-Picado J, Kuritzkes DR, Johnson VA, Richman DD, D'Aquila RT. Comparative analysis of HIV type 1 genotypic resistance across antiretroviral trial treatment regimens. Aids Research and Human Retroviruses. 16: 1325-36. PMID 11018852 DOI: 10.1089/08892220050140874  0.501
2000 Martinez-Picado J, DePasquale MP, Kartsonis N, Hanna GJ, Wong J, Finzi D, Rosenberg E, Gunthard HF, Sutton L, Savara A, Petropoulos CJ, Hellmann N, Walker BD, Richman DD, Siliciano R, et al. Antiretroviral resistance during successful therapy of HIV type 1 infection. Proceedings of the National Academy of Sciences of the United States of America. 97: 10948-53. PMID 11005867 DOI: 10.1073/Pnas.97.20.10948  0.607
2000 Ioannidis JP, Havlir DV, Tebas P, Hirsch MS, Collier AC, Richman DD. Dynamics of HIV-1 viral load rebound among patients with previous suppression of viral replication. Aids (London, England). 14: 1481-8. PMID 10983634 DOI: 10.1097/00002030-200007280-00003  0.491
2000 Babiker A, Bartlett J, Breckenridge A, Collins G, Coombs R, Cooper D, Creagh T, Cross A, Daniels M, Darbyshire J, Dawson D, DeGruttola V, DeMasi R, Dolin R, Eron J, ... ... Richman D, et al. Human immunodeficiency virus type 1 RNA level and CD4 count as prognostic markers and surrogate end points: A meta-analysis Aids Research and Human Retroviruses. 16: 1123-1133. PMID 10954887 DOI: 10.1089/088922200414965  0.435
2000 Binley JM, Trkola A, Ketas T, Schiller D, Clas B, Little S, Richman D, Hurley A, Markowitz M, Moore JP. The effect of highly active antiretroviral therapy on binding and neutralizing antibody responses to human immunodeficiency virus type 1 infection. The Journal of Infectious Diseases. 182: 945-9. PMID 10950795 DOI: 10.1086/315774  0.499
2000 Tighe H, Takabayashi K, Schwartz D, Marsden R, Beck L, Corbeil J, Richman DD, Eiden JJ, Spiegelberg HL, Raz E. Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity. European Journal of Immunology. 30: 1939-47. PMID 10940883 DOI: 10.1002/1521-4141(200007)30:7<1939::Aid-Immu1939>3.0.Co;2-#  0.36
2000 Hostetler KY, Hammond JL, Kini GD, Hostetler SE, Beadle JR, Aldern KA, Chou TC, Richman DD, Mellors JW. In vitro anti-HIV-1 activity of sn-2-substituted 1-O-octadecyl-sn-glycero-3-phosphonoformate analogues and synergy with zidovudine. Antiviral Chemistry & Chemotherapy. 11: 213-9. PMID 10901292 DOI: 10.1177/095632020001100304  0.447
2000 Pillay D, Taylor S, Richman DD. Incidence and impact of resistance against approved antiretroviral drugs Reviews in Medical Virology. 10: 231-253. PMID 10891871 DOI: 10.1002/1099-1654(200007/08)10:4<231::Aid-Rmv290>3.0.Co;2-P  0.445
2000 Havlir DV, Tierney C, Friedland GH, Pollard RB, Smeaton L, Sommadossi JP, Fox L, Kessler H, Fife KH, Richman DD. In vivo antagonism with zidovudine plus stavudine combination therapy. The Journal of Infectious Diseases. 182: 321-5. PMID 10882616 DOI: 10.1086/315683  0.513
2000 Appay V, Nixon DF, Donahoe SM, Gillespie GM, Dong T, King A, Ogg GS, Spiegel HM, Conlon C, Spina CA, Havlir DV, Richman DD, Waters A, Easterbrook P, McMichael AJ, et al. HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function. The Journal of Experimental Medicine. 192: 63-75. PMID 10880527 DOI: 10.1084/Jem.192.1.63  0.51
2000 Hanna GJ, Johnson VA, Kuritzkes DR, Richman DD, Martinez-Picado J, Sutton L, Hazelwood JD, D'Aquila RT. Comparison of sequencing by hybridization and cycle sequencing for genotyping of human immunodeficiency virus type 1 reverse transcriptase. Journal of Clinical Microbiology. 38: 2715-21. PMID 10878069 DOI: 10.1128/Jcm.38.7.2715-2721.2000  0.302
2000 Gulick RM, Mellors JW, Havlir D, Eron JJ, Meibohm A, Condra JH, Valentine FT, McMahon D, Gonzalez C, Jonas L, Emini EA, Chodakewitz JA, Isaacs R, Richman DD. 3-year suppression of HIV viremia with indinavir, zidovudine, and lamivudine. Annals of Internal Medicine. 133: 35-9. PMID 10877738 DOI: 10.7326/0003-4819-133-1-200007040-00007  0.602
2000 Gifford AL, Bormann JE, Shively MJ, Wright BC, Richman DD, Bozzette SA. Predictors of self-reported adherence and plasma HIV concentrations in patients on multidrug antiretroviral regimens. Journal of Acquired Immune Deficiency Syndromes (1999). 23: 386-95. PMID 10866231 DOI: 10.1097/00126334-200004150-00005  0.516
2000 Richman DD. Principles of HIV resistance testing and overview of assay performance characteristics Antiviral Therapy. 5: 27-31. PMID 10846590  0.328
2000 O'Brien TR, McDermott DH, Ioannidis JP, Carrington M, Murphy PM, Havlir DV, Richman DD. Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapy. Aids (London, England). 14: 821-6. PMID 10839590 DOI: 10.1097/00002030-200005050-00008  0.546
2000 Hirsch MS, Brun-Vézinet F, D'Aquila RT, Hammer SM, Johnson VA, Kuritzkes DR, Loveday C, Mellors JW, Clotet B, Conway B, Demeter LM, Vella S, Jacobsen DM, Richman DD. Antiretroviral drug resistance testing in adult HIV-1 infection: recommendations of an International AIDS Society-USA Panel. Jama. 283: 2417-26. PMID 10815085 DOI: 10.1001/Jama.283.18.2417  0.562
2000 Hanna GJ, Johnson VA, Kuritzkes DR, Richman DD, Brown AJ, Savara AV, Hazelwood JD, D'Aquila RT. Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine. The Journal of Infectious Diseases. 181: 904-11. PMID 10720511 DOI: 10.1086/315329  0.329
2000 Precious HM, Günthard HF, Wong JK, D'Aquila RT, Johnson VA, Kuritzkes DR, Richman DD, Leigh Brown AJ. Multiple sites in HIV-1 reverse transcriptase associated with virological response to combination therapy. Aids (London, England). 14: 31-6. PMID 10714565 DOI: 10.1097/00002030-200001070-00004  0.449
2000 Richman DD. Normal physiology and HIV pathophysiology of human T-cell dynamics Journal of Clinical Investigation. 105: 565-566. PMID 10712427 DOI: 10.1172/Jci9478  0.578
2000 Günthard HF, Wong JK, Spina CA, Ignacio C, Kwok S, Christopherson C, Hwang J, Haubrich R, Havlir D, Richman DD. Effect of influenza vaccination on viral replication and immune response in persons infected with human immunodeficiency virus receiving potent antiretroviral therapy. The Journal of Infectious Diseases. 181: 522-31. PMID 10669335 DOI: 10.1086/315260  0.542
2000 Carpenter CC, Cooper DA, Fischl MA, Gatell JM, Gazzard BG, Hammer SM, Hirsch MS, Jacobsen DM, Katzenstein DA, Montaner JS, Richman DD, Saag MS, Schechter M, Schooley RT, Thompson MA, et al. Antiretroviral therapy in adults: updated recommendations of the International AIDS Society-USA Panel. Jama. 283: 381-90. PMID 10647802 DOI: 10.1001/Jama.283.3.381  0.458
2000 Havlir DV, Hellmann NS, Petropoulos CJ, Whitcomb JM, Collier AC, Hirsch MS, Tebas P, Sommadossi JP, Richman DD. Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens. Jama. 283: 229-34. PMID 10634339 DOI: 10.1001/Jama.283.2.229  0.562
2000 Schacker T, Little S, Connick E, Gebhard-Mitchell K, Zhang ZQ, Krieger J, Pryor J, Havlir D, Wong JK, Richman D, Corey L, Haase AT. Rapid accumulation of human immunodeficiency virus (HIV) in lymphatic tissue reservoirs during acute and early HIV infection: implications for timing of antiretroviral therapy. The Journal of Infectious Diseases. 181: 354-7. PMID 10608788 DOI: 10.1086/315178  0.598
2000 Gifford AL, Bormann JE, Shively MJ, Wright BC, Richman DD, Bozzette SA. Predictors of Self-Reported Adherence and Plasma HIV Concentrations in Patients on Multidrug Antiretroviral Regimens Journal of Acquired Immune Deficiency Syndromes. 23: 386-395. DOI: 10.1097/00042560-200004150-00005  0.363
1999 Haubrich R, Thompson M, Schooley R, Lang W, Stein A, Sereni D, van der Ende ME, Antunes F, Richman D, Pagano G, Kahl L, Fetter A, Brown DJ, Clumeck N. A phase II safety and efficacy study of amprenavir in combination with zidovudine and lamivudine in HIV-infected patients with limited antiretroviral experience. Amprenavir PROAB2002 Study Team. Aids (London, England). 13: 2411-20. PMID 10597783 DOI: 10.1097/00002030-199912030-00013  0.464
1999 Zhang Z, Schuler T, Zupancic M, Wietgrefe S, Staskus KA, Reimann KA, Reinhart TA, Rogan M, Cavert W, Miller CJ, Veazey RS, Notermans D, Little S, Danner SA, Richman DD, et al. Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells. Science (New York, N.Y.). 286: 1353-7. PMID 10558989 DOI: 10.1126/Science.286.5443.1353  0.565
1999 Richman D, Crowe S, Harvey K. HIV viral load monitoring. Advances in Experimental Medicine and Biology. 458: 199-212. PMID 10549392 DOI: 10.1007/978-1-4615-4743-3_19  0.582
1999 Günthard HF, Frost SD, Leigh-Brown AJ, Ignacio CC, Kee K, Perelson AS, Spina CA, Havlir DV, Hezareh M, Looney DJ, Richman DD, Wong JK. Evolution of envelope sequences of human immunodeficiency virus type 1 in cellular reservoirs in the setting of potent antiviral therapy. Journal of Virology. 73: 9404-12. PMID 10516049 DOI: 10.1128/Jvi.73.11.9404-9412.1999  0.505
1999 Brodine SK, Shaffer RA, Starkey MJ, Tasker SA, Gilcrest JL, Louder MK, Barile A, VanCott TC, Vahey MT, McCutchan FE, Birx DL, Richman DD, Mascola JR. Drug resistance patterns, genetic subtypes, clinical features, and risk factors in military personnel with HIV-1 seroconversion. Annals of Internal Medicine. 131: 502-6. PMID 10507958 DOI: 10.7326/0003-4819-131-7-199910050-00004  0.579
1999 Little SJ, Daar ES, D'Aquila RT, Keiser PH, Connick E, Whitcomb JM, Hellmann NS, Petropoulos CJ, Sutton L, Pitt JA, Rosenberg ES, Koup RA, Walker BD, Richman DD. Reduced antiretroviral drug susceptibility among patients with primary HIV infection. Jama. 282: 1142-9. PMID 10501117 DOI: 10.1001/Jama.282.12.1142  0.589
1999 Little SJ, McLean AR, Spina CA, Richman DD, Havlir DV. Viral dynamics of acute HIV-1 infection. The Journal of Experimental Medicine. 190: 841-50. PMID 10499922 DOI: 10.1084/Jem.190.6.841  0.6
1999 Richman D. The challenge of immune control of immunodeficiency virus. Journal of Clinical Investigation. 104: 677-678. PMID 10491402 DOI: 10.1172/Jci8242  0.596
1999 Craig HM, Pandori MW, Riggs NL, Richman DD, Guatelli JC. Analysis of the SH3-binding region of HIV-1 nef: partial functional defects introduced by mutations in the polyproline helix and the hydrophobic pocket. Virology. 262: 55-63. PMID 10489340 DOI: 10.1006/Viro.1999.9897  0.339
1999 Vázquez-Rosales G, García Lerma JG, Yamamoto S, Switzer WM, Havlir D, Folks TM, Richman DD, Heneine W. Rapid screening of phenotypic resistance to nevirapine by direct analysis of HIV type 1 reverse transcriptase activity in plasma. Aids Research and Human Retroviruses. 15: 1191-200. PMID 10480632 DOI: 10.1089/088922299310287  0.512
1999 Brown AJ, Günthard HF, Wong JK, D'Aquila RT, Johnson VA, Kuritzkes DR, Richman DD. Sequence clusters in human immunodeficiency virus type 1 reverse transcriptase are associated with subsequent virological response to antiretroviral therapy. The Journal of Infectious Diseases. 180: 1043-9. PMID 10479129 DOI: 10.1086/315017  0.334
1999 Günthard HF, Leigh-Brown AJ, D'Aquila RT, Johnson VA, Kuritzkes DR, Richman DD, Wong JK, D'aquila RT. Higher selection pressure from antiretroviral drugs in vivo results in increased evolutionary distance in HIV-1 pol. Virology. 259: 154-65. PMID 10364500 DOI: 10.1006/Viro.1999.9774  0.44
1999 Zhang ZQ, Schuler T, Cavert W, Notermans DW, Gebhard K, Henry K, Havlir DV, Günthard HF, Wong JK, Little S, Feinberg MB, Polis MA, Schrager LK, Schacker TW, Richman DD, et al. Reversibility of the pathological changes in the follicular dendritic cell network with treatment of HIV-1 infection Proceedings of the National Academy of Sciences of the United States of America. 96: 5169-5172. PMID 10220437 DOI: 10.1073/Pnas.96.9.5169  0.523
1999 Günthard HF, Frost SDW, Leigh-Brown AJ, Ignacio CC, Kee K, Perelson AS, Spina CA, Havlir DV, Hezareh M, Looney DJ, Richman DD, Wong JK. Evolution of Envelope Sequences of Human Immunodeficiency Virus Type 1 in Cellular Reservoirs in the Setting of Potent Antiviral Therapy Journal of Virology. 73: 9404-9412. DOI: 10.1128/jvi.73.11.9404-9412.1999  0.407
1999 Corbeil J, Sheeter D, Rought S, Du P, Ferguson M, Masys DR, Welsh JB, Huang D, Drenkow J, Richman DD, Gingeras T. Magnitude and specificity of temporal gene expression during HIV-1 infection of a CD4+ T cell Nature Genetics. 23: 39-40. DOI: 10.1038/14288  0.84
1998 Beadle JR, Kini GD, Aldern KA, Gardner MF, Wright KN, Richman DD, Hostetler KY. Alkylthioglycerol prodrugs of foscarnet: synthesis, oral bioavailability and structure-activity studies in human cytomegalovirus-, herpes simplex virus type 1- and human immunodeficiency virus type 1-infected cells. Antiviral Chemistry & Chemotherapy. 9: 33-40. PMID 9875375 DOI: 10.1177/095632029800900104  0.462
1998 Demeter LM, D'Aquila R, Weislow O, Lorenzo E, Erice A, Fitzgibbon J, Shafer R, Richman D, Howard TM, Zhao Y, Fisher E, Huang D, Mayers D, Sylvester S, Arens M, et al. Interlaboratory concordance of DNA sequence analysis to detect reverse transcriptase mutations in HIV-1 proviral DNA. ACTG Sequencing Working Group. AIDS Clinical Trials Group. Journal of Virological Methods. 75: 93-104. PMID 9820578 DOI: 10.1016/S0166-0934(98)00100-1  0.419
1998 Richman DD. Nailing down another HIV target Nature Medicine. 4: 1232-1233. PMID 9809537 DOI: 10.1038/3209  0.544
1998 Havlir DV, Marschner IC, Hirsch MS, Collier AC, Tebas P, Bassett RL, Ioannidis JP, Holohan MK, Leavitt R, Boone G, Richman DD. Maintenance antiretroviral therapies in HIV infected patients with undetectable plasma HIV RNA after triple-drug therapy. AIDS Clinical Trials Group Study 343 Team. The New England Journal of Medicine. 339: 1261-8. PMID 9791141 DOI: 10.1056/Nejm199810293391801  0.554
1998 Riggs NL, Little SJ, Richman DD, Guatelli JC. Cell-associated viral rNA expression during acute infection with HIV type 1 Aids Research and Human Retroviruses. 14: 1141-1149. PMID 9737585 DOI: 10.1089/Aid.1998.14.1141  0.457
1998 Moutouh L, Estaquier J, Richman DD, Corbeil J. Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors Journal of Virology. 72: 8061-8072. PMID 9733846 DOI: 10.1128/Jvi.72.10.8061-8072.1998  0.487
1998 Günthard HF, Wong JK, Ignacio CC, Havlir DV, Richman DD. Comparative performance of high-density oligonucleotide sequencing and dideoxynucleotide sequencing of HIV type 1 pol from clinical samples Aids Research and Human Retroviruses. 14: 869-876. PMID 9671215 DOI: 10.1089/Aid.1998.14.869  0.367
1998 Carpenter CC, Fischl MA, Hammer SM, Hirsch MS, Jacobsen DM, Katzenstein DA, Montaner JS, Richman DD, Saag MS, Schooley RT, Thompson MA, Vella S, Yeni PG, Volberding PA. Antiretroviral therapy for HIV infection in 1998: updated recommendations of the International AIDS Society-USA Panel. Jama. 280: 78-86. PMID 9660368 DOI: 10.1001/Jama.1997.03540480062040  0.539
1998 Gulick RM, Mellors JW, Havlir D, Eron JJ, Gonzalez C, McMahon D, Jonas L, Meibohm A, Holder D, Schleif WA, Condra JH, Emini EA, Isaacs R, Chodakewitz JA, Richman DD. Simultaneous vs sequential initiation of therapy with indinavir, zidovudine, and lamivudine for HIV-1 infection: 100-week follow-up Journal of the American Medical Association. 280: 35-41. PMID 9660361 DOI: 10.1001/Jama.280.1.35  0.567
1998 Hirsch MS, Conway B, D'Aquila RT, Johnson VA, Brun-Vézinet F, Clotet B, Demeter LM, Hammer SM, Jacobsen DM, Kuritzkes DR, Loveday C, Mellors JW, Vella S, Richman DD. Antiretroviral drug resistance testing in adults with HIV infection: implications for clinical management. International AIDS Society--USA Panel. Jama. 279: 1984-91. PMID 9643863 DOI: 10.1001/Jama.279.24.1984  0.52
1998 Kornbluth RS, Kee K, Richman DD. CD40 ligand (CD154) stimulation of macrophages to produce HIV-1-suppressive β-chemokines Proceedings of the National Academy of Sciences of the United States of America. 95: 5205-5210. PMID 9560254 DOI: 10.1073/Pnas.95.9.5205  0.381
1998 Günthard HF, Wong JK, Ignacio CC, Guatelli JC, Riggs NL, Havlir DV, Richman DD. Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy Journal of Virology. 72: 2422-2428. PMID 9499103 DOI: 10.1128/Jvi.72.3.2422-2428.1998  0.473
1998 Havlir DV, Haubrich R, Hwang J, Dunne MW, Currier J, Forthal D, Torriani F, Richman DD, McCutchan JA. Human immunodeficiency virus replication in AIDS patients with Mycobacterium avium complex bacteremia: A case control study Journal of Infectious Diseases. 177: 595-599. PMID 9498437 DOI: 10.1086/514220  0.563
1998 De Jong MD, Boucher CAB, Danner SA, Gazzard B, Griffiths PD, Katlama C, Lange JMA, Richman DD, Vella S. Summary of the international consensus symposium on management of HIV, CMV and hepatitis virus infections Antiviral Research. 37: 1-16. PMID 9497068 DOI: 10.1016/S0166-3542(97)00059-4  0.545
1998 Marschner IC, Collier AC, Coombs RW, D'Aquila RT, DeGruttola V, Fischl MA, Hammer SM, Hughes MD, Johnson VA, Katzenstein DA, Richman DD, Smeaton LM, Spector SA, Saag MS. Use of changes in plasma levels of human immunodeficiency virus type 1 RNA to assess the clinical benefit of antiretroviral therapy. The Journal of Infectious Diseases. 177: 40-7. PMID 9419168 DOI: 10.1086/513823  0.545
1998 Bessudo A, Rassenti L, Havlir D, Richman D, Feigal E, Kipps TJ. Aberrant and Unstable Expression of Immunoglobulin Genes in Persons Infected With Human Immunodeficiency Virus Blood. 92: 1317-1323. DOI: 10.1182/Blood.V92.4.1317  0.518
1998 Günthard HF, Wong JK, Ignacio CC, Guatelli JC, Riggs NL, Havlir DV, Richman DD. Human Immunodeficiency Virus Replication and Genotypic Resistance in Blood and Lymph Nodes after a Year of Potent Antiretroviral Therapy Journal of Virology. 72: 2422-2428. DOI: 10.1128/jvi.72.3.2422-2428.1998  0.369
1998 Minshull C, Boucher C, Richman DD. 2nd International Workshop on HIV Drug Resistance and Treatment Strategies, Lake Maggiore, Italy, 24-27 June: Meeting report International Antiviral News. 6: 130-135.  0.307
1997 Fischl MA, Richman DD, Saag M, Meng TC, Squires KE, Holden-Wiltse J, Meehan PM. Safety and antiviral activity of combination therapy with zidovudine, zalcitabine, and two doses of interferon-alpha2a in patients with HIV. AIDS Clinical Trials Group Study 197. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 16: 247-53. PMID 9402071 DOI: 10.1097/00042560-199712010-00005  0.414
1997 Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, Chaisson RE, Quinn TC, Chadwick K, Margolick J, Brookmeyer R, Gallant J, Markowitz M, Ho DD, Richman DD, Siliciano RF. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science (New York, N.Y.). 278: 1295-300. PMID 9360927 DOI: 10.1126/Science.278.5341.1295  0.534
1997 Wong JK, Hezareh M, Günthard HF, Havlir DV, Ignacio CC, Spina CA, Richman DD. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science (New York, N.Y.). 278: 1291-5. PMID 9360926 DOI: 10.1126/Science.278.5341.1291  0.565
1997 Wong JK, Günthard HF, Havlir DV, Zhang ZQ, Haase AT, Ignacio CC, Kwok S, Emini E, Richman DD. Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure. Proceedings of the National Academy of Sciences of the United States of America. 94: 12574-9. PMID 9356491 DOI: 10.1073/Pnas.94.23.12574  0.49
1997 Kini GD, Beadle JR, Xie H, Aldern KA, Richman DD, Hostetler KY. Alkoxy propane prodrugs of foscarnet: effect of alkyl chain length on in vitro antiviral activity in cells infected with HIV-1, HSV-1 and HCMV. Antiviral Research. 36: 43-53. PMID 9330760 DOI: 10.1016/S0166-3542(97)00039-9  0.533
1997 Gulick RM, Mellors JW, Havlir D, Eron JJ, Gonzalez C, McMahon D, Richman DD, Valentine FT, Jonas L, Meibohm A, Emini EA, Chodakewitz JA, Deutsch P, Holder D, Schleif WA, et al. Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy New England Journal of Medicine. 337: 734-739. PMID 9287228 DOI: 10.1056/Nejm199709113371102  0.577
1997 Rosowsky A, Fu H, Pai N, Mellors J, Richman DD, Hostetler KY. Synthesis and in vitro activity of long-chain 5'-O- [(alkoxycarbonyl)phosphinyl]-3'axido-3'-azido-3'-deoxythymidines against wild-type and AZT- and foscarnet-resistant strains of HIV-1 Journal of Medicinal Chemistry. 40: 2482-2490. PMID 9258355 DOI: 10.1021/Jm970172F  0.38
1997 Fischl MA, Richman DD, Flexner C, Para MF, Haubrich R, Karim A, Yeramian P, Holden-Wiltse J, Meehan PM. Phase I/II study of the toxicity, pharmacokinetics, and activity of the HIV protease inhibitor SC-52151 Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 15: 28-34. PMID 9215651 DOI: 10.1097/00042560-199705010-00005  0.432
1997 Spina CA, Prince HE, Richman DD. Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro. The Journal of Clinical Investigation. 99: 1774-85. PMID 9120023 DOI: 10.1172/Jci119342  0.52
1997 Gervaix A, West D, Leoni LM, Richman DD, Wong-Staal F, Corbeil J. A new reporter cell line to monitor HIV infection and drug susceptibility in vitro Proceedings of the National Academy of Sciences of the United States of America. 94: 4653-4658. PMID 9114046 DOI: 10.1073/Pnas.94.9.4653  0.58
1997 Havlir DV, Richman DD. The role of viral dynamics in the pathogenesis of HIV disease and implications for antiviral therapy Springer Seminars in Immunopathology. 18: 267-283. PMID 9089949 DOI: 10.1007/Bf00813498  0.599
1997 Leigh Brown AJ, Richman DD. HIV-1: Gambling on the evolution of drug resistance? Nature Medicine. 3: 268-271. PMID 9055846 DOI: 10.1038/Nm0397-268  0.582
1997 Marschner IC, Mayers DL, Erice A, Smeaton L, Johnson VA, Richman DD, Reichelderfer P, Japour AJ. Standardized peripheral blood mononuclear cell culture assay for zidovudine susceptibility testing of clinical human immunodeficiency virus type 1 isolates: effect of reducing the numbers of replicates and concentrations. Journal of Clinical Microbiology. 35: 756-8. PMID 9041428 DOI: 10.1128/Jcm.35.3.756-758.1997  0.336
1997 Wong JK, Ignacio CC, Torriani F, Havlir D, Fitch NJ, Richman DD. In vivo compartmentalization of human immunodeficiency virus: evidence from the examination of pol sequences from autopsy tissues. Journal of Virology. 71: 2059-71. PMID 9032338 DOI: 10.1128/Jvi.71.3.2059-2071.1997  0.43
1997 Smidt ML, Potts KE, Tucker SP, Blystone L, Stiebel TR, Stallings WC, McDonald JJ, Pillay D, Richman DD, Bryant ML. A mutation in human immunodeficiency virus type 1 protease at position 88, located outside the active site, confers resistance to the hydroxyethylurea inhibitor SC-55389A. Antimicrobial Agents and Chemotherapy. 41: 515-522. DOI: 10.1128/AAC.41.3.515  0.304
1997 Bessudo A, Rassenti L, Richman D, Havlir D, Feigal E, Kipps TJ. SKEWED AND UNSTABLE B-CELL REPERTOIRE IN SERIAL BLOOD SAMPLES OF HIV INFECTED PATIENTS. POTENTIAL ROLE IN THE INDUCTION OF AIDS-ASSOCIATED LYMPHOMA Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. 14: A51. DOI: 10.1097/00042560-199704010-00180  0.532
1997 Looney DJ, Witke W, Feigal E, Corbeil J, Richman D, Little S. Relationship of HHV-8 Peripheral Blood Mononuclear Cell Burden to Immunodeficiency, Opportunistic Infections, Response to Therapy, and Stage of Kaposi's Sarcoma Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. 14: A36. DOI: 10.1097/00042560-199704010-00121  0.362
1997 Rosowsky A, Fu H, Pai N, Mellors J, Richman D, Hostetler K. Synthesis and in vitro antiviral activity of long-chain 5′-O-alkoxycarbonylphosphinyl)-3′-azido-3′-deoxythymidines against drug-sensitive and AZT- or PFA-resistant human immunodeficiency virus type-1 (HIV-1) Antiviral Research. 34: A43. DOI: 10.1016/S0166-3542(97)83150-6  0.477
1997 Richman DD. Drug resistance and its implications in the management of HIV infection Antiviral Therapy. 2: 41-58.  0.441
1996 Bozzette SA, Kanouse DE, Duan N, Berry S, Richman DD. The impact of zidovudine compared with didanosine on health status and functioning in persons with advanced HIV infection and a varying duration of prior zidovudine therapy Antiviral Therapy. 1: 21-32. PMID 11322256  0.308
1996 Lange JM, Richman DD. Can HIV infection be cured? Antiviral Therapy. 1: 126-128. PMID 11322245  0.522
1996 Richman DD. New strategies to combat HIV drug resistance Hospital Practice. 31: 47-66. PMID 9119931 DOI: 10.1080/21548331.1996.11443331  0.408
1996 Havlir DV, Eastman S, Gamst A, Richman DD. Nevirapine-resistant human immunodeficiency virus: Kinetics of replication and estimated prevalence in untreated patients Journal of Virology. 70: 7894-7899. PMID 8892912 DOI: 10.1128/Jvi.70.11.7894-7899.1996  0.546
1996 Coombs RW, Welles SL, Hooper C, Reichelderfer PS, D'Aquila RT, Japour AJ, Johnson VA, Kuritzkes DR, Richman DD, Kwok S, Todd J, Jackson JB, Degruttola V, Crumpacker CS, Kahn J. Association of plasma human immunodeficiency virus type 1 RNA level with risk of clinical progression in patients with advanced infection Journal of Infectious Diseases. 174: 704-712. PMID 8843206 DOI: 10.1093/Infdis/174.4.704  0.544
1996 Welles SL, Jackson JB, Yen-Lieberman B, Demeter L, Japour AJ, Smeaton LM, Johnson VA, Kuritzkes DR, D'Aquila RT, Reichelderfer PA, Richman DD, Reichman R, Fischl M, Dolin R, Coombs RW, et al. Prognostic value of plasma human immunodeficiency virus type 1 (HIV-1) RNA levels in patients with advanced HIV-1 disease and with little or no prior zidovudine therapy. AIDS Clinical Trials Group Protocol 116A/116B/117 Team. The Journal of Infectious Diseases. 174: 696-703. PMID 8843205 DOI: 10.1093/Infdis/174.4.696  0.541
1996 Richman DD. Anteretroviral drug resistance: Mechanisms, pathogenesis, clinical significance Advances in Experimental Medicine and Biology. 394: 383-395. PMID 8815703 DOI: 10.1007/978-1-4757-9209-6_35  0.331
1996 Hostetler KY, Kini GD, Beadle JR, Aldern KA, Gardner MF, Border R, Kumar R, Barshak L, Sridhar CN, Wheeler CJ, Richman DD. Lipid prodrugs of phosphonoacids: greatly enhanced antiviral activity of 1-O-octadecyl-sn-glycero-3-phosphonoformate in HIV-1, HSV-1 and HCMV-infected cells, in vitro. Antiviral Research. 31: 59-67. PMID 8793009 DOI: 10.1016/0166-3542(96)00947-3  0.446
1996 Richman DD. The implications of drug resistance for strategies of combination antiviral chemotherapy Antiviral Research. 29: 31-33. PMID 8721540 DOI: 10.1016/0166-3542(95)00911-6  0.464
1996 Pandori MW, Fitch NJ, Craig HM, Richman DD, Spina CA, Guatelli JC. Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein. Journal of Virology. 70: 4283-90. PMID 8676450 DOI: 10.1128/Jvi.70.7.4283-4290.1996  0.434
1996 Kozal MJ, Shah N, Shen N, Yang R, Fucini R, Merigan TC, Richman DD, Morris D, Hubbell E, Chee M, Gingeras TR. Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays. Nature Medicine. 2: 753-9. PMID 8673920 DOI: 10.1038/Nm0796-753  0.546
1996 Richman DD. HIV therapeutics Science. 272: 1886-1888. PMID 8658159 DOI: 10.1126/science.272.5270.1886  0.487
1996 Moutouh L, Corbeil J, Richman DD. Recombination leads to the rapid emergence of HIV-1 dually resistant mutants under selective drug pressure Proceedings of the National Academy of Sciences of the United States of America. 93: 6106-6111. PMID 8650227 DOI: 10.1073/Pnas.93.12.6106  0.491
1996 Saag MS, Holodniy M, Kuritzkes DR, O'Brien WA, Coombs R, Poscher ME, Jacobsen DM, Shaw GM, Richman DD, Volberding PA. HIV viral load markers in clinical practice. Nature Medicine. 2: 625-9. PMID 8640545 DOI: 10.1038/Nm0696-625  0.525
1996 Havlir DV, Richman DD. Viral dynamics of HIV: Implications for drug development and therapeutic strategies Annals of Internal Medicine. 124: 984-994. PMID 8624066 DOI: 10.7326/0003-4819-124-11-199606010-00006  0.585
1996 Corbeil J, Tremblay M, Richman DD. HIV-induced apoptosis requires the CD4 receptor cytoplasmic tail and is accelerated by interaction of CD4 with p56lck Journal of Experimental Medicine. 183: 39-48. PMID 8551242 DOI: 10.1084/Jem.183.1.39  0.438
1996 Zhang H, Dornadula G, Wu Y, Havlir D, Richman DD, Pomerantz RJ. Kinetic analysis of intravirion reverse transcription in the blood plasma of human immunodeficiency virus type 1-infected individuals: direct assessment of resistance to reverse transcriptase inhibitors in vivo. Journal of Virology. 70: 628-634. DOI: 10.1128/Jvi.70.1.628-634.1996  0.595
1995 Richman DD. Clinical significance of drug resistance in human immunodeficiency virus Clinical Infectious Diseases. 21. PMID 8845446 DOI: 10.1093/Clinids/21.Supplement_2.S166  0.329
1995 Xie H, Voronkov M, Liotta DC, Korba BA, Schinazi RF, Richman DD, Hostetler KY. Phosphatidyl-2',3'-dideoxy-3'-thiacytidine: synthesis and antiviral activity in hepatitis B-and HIV-1-infected cells. Antiviral Research. 28: 113-20. PMID 8585765 DOI: 10.1016/0166-3542(95)00042-K  0.429
1995 Corbeil J, Richman DD. Productive infection and subsequent interaction of CD4-gp120 at the cellular membrane is required for HIV-induced apoptosis of CD4+ T cells Journal of General Virology. 76: 681-690. PMID 7897356 DOI: 10.1099/0022-1317-76-3-681  0.562
1995 D'Aquila RT, Johnson VA, Welles SL, Japour AJ, Kuritzkes DR, DeGruttola V, Reichelderfer PS, Coombs RW, Crumpacker CS, Kahn JO, Richman DD. Zidovudine resistance and HIV-1 disease progression during antiretroviral therapy. AIDS Clinical Trials Group Protocol 116B/117 Team and the Virology Committee Resistance Working Group. Annals of Internal Medicine. 122: 401-8. PMID 7856987 DOI: 10.7326/0003-4819-122-6-199503150-00001  0.517
1995 Bozzette SA, Forthal D, Sattler FR, Kemper C, Richman DD, Tilles JG, Leedom J, McCutchan JA. The tolerance for zidovudine plus thrice weekly or daily trimethoprim-sulfamethoxazole with and without leucovorin for primary prophylaxis in advanced HIV disease. California Collaborative Treatment Group. The American Journal of Medicine. 98: 177-82. PMID 7847434 DOI: 10.1016/S0002-9343(99)80401-X  0.56
1995 Luznik L, Kraus G, Guatelli J, Richman D, Wong-Staal F. Tat-independent replication of human immunodeficiency viruses Journal of Clinical Investigation. 95: 328-332. PMID 7814633 DOI: 10.1172/Jci117660  0.548
1995 Corbeil J, Evans LA, McQueen PW, Vasak E, Edward PD, Richman DD, Penny R, Cooper DA. Productive in vitro infection of human umbilical vein endothelial cells and three colon carcinoma cell lines with HIV-1. Immunology and Cell Biology. 73: 140-5. PMID 7797233 DOI: 10.1038/Icb.1995.22  0.596
1995 Spina CA, Guatelli JC, Richman DD. Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro Journal of Virology. 69: 2977-2988. PMID 7707524 DOI: 10.1128/Jvi.69.5.2977-2988.1995  0.538
1995 Gallant JE, Moore RD, Keruly J, Richman DD, Chaisson RE. Lack of association between acyclovir use and survival in patients with advanced human immunodeficiency virus disease treated with zidovudine. Zidovudine Epidemiology Study Group. The Journal of Infectious Diseases. 172: 346-52. PMID 7622876 DOI: 10.1093/Infdis/172.2.346  0.404
1995 Richman DD, Havlir D. Early Versus Delayed Treatment of HIV Infection: Zidovudine Should be Given Before Symptoms Develop Drugs. 49: 9-16. PMID 7614902 DOI: 10.2165/00003495-199500491-00005  0.547
1995 Havlir D, Mc Laughlin MM, Richman DD. A pilot study to evaluate the development of resistance to nevirapine in asymptomatic human immunodeficiency virus-infected patients with cd4 cell counts of >500/mm3: Aids clinical trials group protocol 208 Journal of Infectious Diseases. 172: 1379-1383. PMID 7594683 DOI: 10.1093/Infdis/172.5.1379  0.573
1995 Haubrich RH, Flexner C, Lederman MM, Hirsch M, Pettinelli CP, Ginsberg R, Lietman P, Hamzeh FM, Spector SA, Richman DD, Hammer S, Cooley T, Gulick R, Sullivan M, Spina C, et al. A randomized trial of the activity and safety of ro 24-7429 (tat antagonist) versus nucleoside for human immunodeficiency virus infection Journal of Infectious Diseases. 172: 1246-1252. PMID 7594660 DOI: 10.1093/Infdis/172.5.1246  0.379
1995 Corbeil J, Richman DD. The role of surface CD4 in HIV-induced apoptosis Advances in Experimental Medicine and Biology. 374: 91-99. PMID 7572403 DOI: 10.1007/978-1-4615-1995-9_8  0.397
1995 Chowers MY, Pandori MW, Spina CA, Richman DD, Guatelli JC. The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation. Virology. 212: 451-7. PMID 7571414 DOI: 10.1006/Viro.1995.1502  0.446
1995 Japour AJ, Welles S, D'Aquila RT, Johnson VA, Richman DD, Coombs RW, Reichelderfer PS, Kahn JO, Crumpacker CS, Kuritzkes DR. Prevalence and clinical significance of zidovudine resistance mutations in human immunodeficiency virus isolated from patients after long-term zidovudine treatment. AIDS Clinical Trials Group 116B/117 Study Team and the Virology Committee Resistance Working Group. The Journal of Infectious Diseases. 171: 1172-9. PMID 7538548 DOI: 10.1093/Infdis/171.5.1172  0.427
1995 Havlir D, Cheeseman SH, Mclaughlin M, Murphy R, Erice A, Spector SA, Greenough TC, Sullivan JL, Hall D, Myers M, Lamson M, Richman DD. High-Dose Nevirapine: Safety, Pharmacokinetics, And Antiviral Effect In Patients With Human Immunodeficiency Virus Infection The Journal of Infectious Diseases. 171: 537-545. PMID 7533197 DOI: 10.1093/Infdis/171.3.537  0.37
1995 Jault FM, Jault JM, Ruchti F, Fortunato EA, Clark C, Corbeil J, Richman DD, Spector DH. Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest Journal of Virology. 69: 6697-6704. PMID 7474079 DOI: 10.1128/Jvi.69.11.6697-6704.1995  0.344
1995 Tierney M, Pottage J, Kessler H, Fischl M, Richman D, Merigan T, Powderly W, Smith S, Karim A, Sherman J. The tolerability and pharmacokinetics of N-butyl-deoxynojirimycin in patients with advanced HIV disease (ACTG 100) Journal of Acquired Immune Deficiency Syndromes. 10: 549-553. DOI: 10.1097/00042560-199510050-00008  0.464
1995 Meng T, Fischl MA, Cheeseman SH, Spector SA, Resnick L, Boota A, Petrakis T, Wright B, Richman DD. Combination Therapy with Recombinant Human Soluble CD4-Immunoglobulin G and Zidovudine in Patients with HIV Infection Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. 8: 152???160. DOI: 10.1097/00042560-199502000-00006  0.375
1995 Cheeseman SH, Havlir D, McLaughlin MM, Greenough TC, Sullivan JL, Hall D, Hattox SE, Spector SA, Stein DS, Myers M, Richman DD. Phase I/II evaluation of nevirapine alone and in combination with zidovudine for infection with human immunodeficiency virus. Journal of Acquired Immune Deficiency Syndromes. 8: 141-151. DOI: 10.1097/00042560-199502000-00005  0.489
1995 Havlir D, Richman DD. Antiretroviral therapy Current Opinion in Infectious Diseases. 8: 66-73. DOI: 10.1097/00001432-199502000-00014  0.467
1995 Pillay D, Bryant M, Getman D, Richman DD. HIV-1 protease inhibitors: Their development, mechanism of action and clinical potential Reviews in Medical Virology. 5: 23-33. DOI: 10.1002/Rmv.1980050104  0.491
1994 Chowers MY, Spina CA, Kwoh TJ, Fitch NJ, Richman DD, Guatelli JC. Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene. Journal of Virology. 68: 2906-14. PMID 8151761 DOI: 10.1128/Jvi.68.5.2906-2914.1994  0.447
1994 Gallant JE, Moore RD, Richman DD, Keruly J, Chaisson RE. Risk factors for Kaposi's sarcoma in patients with advanced human immunodeficiency virus disease treated with zidovudine Archives of Internal Medicine. 154: 566-572. PMID 8122950 DOI: 10.1001/Archinte.1994.00420050132012  0.352
1994 van Wijk GMT, Hostetler KY, Kroneman E, Richman DD, Sridhar CN, Kumar R, van den Bosch H. Synthesis and antiviral activity of 3′-azido-3′-deoxythymidine triphosphate distearoylglycerol: a novel phospholipid conjugate of the anti-HIV agent AZT Chemistry and Physics of Lipids. 70: 213-222. PMID 8033292 DOI: 10.1016/0009-3084(94)90089-2  0.471
1994 Riggs NL, Little SJ, Richman DD, Guatelli JC. Biological importance and cooperativity of HIV-1 regulatory gene splice acceptors Virology. 202: 264-271. PMID 8009838 DOI: 10.1006/Viro.1994.1342  0.336
1994 Little SJ, Riggs NL, Chowers MY, Fitch NJ, Richman DD, Spina CA, Guatelli JC. Cell surface CD4 downregulation and resistance to superinfection induced by a defective provirus of HIV-1. Virology. 205: 578-82. PMID 7975260 DOI: 10.1006/Viro.1994.1683  0.542
1994 Pauza CD, Trivedi P, McKechnie TS, Richman DD, Graziano FM. 2-LTR Circular Viral DNA as a Marker for Human Immunodeficiency Virus Type 1 Infection in Vivo Virology. 205: 470-478. PMID 7975248 DOI: 10.1006/Viro.1994.1667  0.483
1994 Hostetler KY, Richman DD, Forssen EA, Selk L, Basava R, Gardner MF, Parker S, Basava C. Phospholipid prodrug inhibitors of the HIV protease. Antiviral activity and pharmacokinetics in rats Biochemical Pharmacology. 48: 1399-1404. PMID 7945439 DOI: 10.1016/0006-2952(94)90563-0  0.526
1994 Richman DD, Bozzette SA. The impact of the syncytium-inducing phenotype of human immunodeficiency virus on disease progression Journal of Infectious Diseases. 169: 968-974. PMID 7909549 DOI: 10.1093/Infdis/169.5.968  0.44
1994 Spina CA, Kwoh TJ, Chowers MY, Guatelli JC, Richman DD. The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes Journal of Experimental Medicine. 179: 115-123. PMID 7903679 DOI: 10.1084/Jem.179.1.115  0.525
1994 Richman DD. Resistance, drug failure, and disease progression Aids Research and Human Retroviruses. 10: 901-905. PMID 7811540 DOI: 10.1089/Apc.1994.8.317  0.515
1994 Meylan PRA, Kornbluth RS, Zbinden I, Richman DD. Influence of host cell type and V3 loop of the surface glycoprotein on susceptibility of human immunodeficiency virus type 1 to polyanion compounds Antimicrobial Agents and Chemotherapy. 38: 2910-2916. PMID 7695283 DOI: 10.1128/Aac.38.12.2910  0.602
1994 Hostetler KY, Richman DD, Sridhar CN, Felgner PL, Felgner J, Ricci J, Gardner MF, Selleseth DW, Ellis MN. Phosphatidylazidothymidine and phosphatidyl-ddC: Assessment of uptake in mouse lymphoid tissues and antiviral activities in human immunodeficiency virus-infected cells and in Rauscher leukemia virus-infected mice Antimicrobial Agents and Chemotherapy. 38: 2792-2797. PMID 7695264 DOI: 10.1128/Aac.38.12.2792  0.567
1994 Kornbluth RS, Matsuzaki H, Meylan PRA, Richman DD. Interferon interactions with HIV1 in macrophages Research in Immunology. 145: 664-668. PMID 7538687 DOI: 10.1016/S0923-2494(05)80051-3  0.517
1994 Connell EV, Hsu MC, Richman DD. Combinative interactions of a human immunodeficiency virus (HIV) Tat antagonist with HIV reverse transcriptase inhibitors and an HIV protease inhibitor Antimicrobial Agents and Chemotherapy. 38: 348-352. PMID 7514858 DOI: 10.1128/Aac.38.2.348  0.584
1994 Richman DD, Havlir D, Corbeil J, Looney D, Ignacio C, Spector SA, Sullivan J, Cheeseman S, Barringer K, Pauletti D. Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy. Journal of Virology. 68: 1660-1666. DOI: 10.1128/Jvi.68.3.1660-1666.1994  0.472
1994 Richman DD. HIV DRUG RESISTANCE Aids. 8: S3. DOI: 10.1097/00002030-199411004-00010  0.517
1994 Sato Y, Maruyama T, Utzumi K, Richman DD. Synthesis and anti-hiv activity of 6-substituted purine 2'-deoxy-2’-fluororibosides1) Nucleosides and Nucleotides. 13: 527-537. DOI: 10.1080/15257779408013260  0.316
1994 Havlir D, Richman DD. Zidovudine should be given before HIV-positive individuals develop symptoms Reviews in Medical Virology. 4: 75-80. DOI: 10.1002/Rmv.1980040202  0.487
1993 Meylan PRA, Spina CA, Richman DD, Kornbluth RS. In vitro differentiation of monocytoid THP-1 cells affects their permissiveness for HIV strains: A model system for studying the cellular basis of HIV differential tropism Virology. 193: 256-267. PMID 8438570 DOI: 10.1006/Viro.1993.1121  0.6
1993 Kornbluth RS, Rhodes J, Richman DD. Recovery of infectious HIV following the passage of apoptotic cellular debris through phagocytic macrophages Chest. 103. PMID 8428523 DOI: 10.1378/Chest.103.2_Supplement.102S-A  0.552
1993 Pauza CD, Kornbluth R, Emau P, Richman DD, Deftos LJ. Vitamin D3 compounds regulate human immunodeficiency virus type 1 replication in U937 monoblastoid cells and in monocyte-derived macrophages Journal of Leukocyte Biology. 53: 157-164. PMID 8383166 DOI: 10.1002/Jlb.53.2.157  0.504
1993 Kohsaka H, Taniguchi A, Richman DD, Carson DA. Microtiter format gene quantification by covalent capture of competitive PCR products: Application to HIV-1 detection Nucleic Acids Research. 21: 3469-3472. PMID 8346024 DOI: 10.1093/Nar/21.15.3469  0.36
1993 Richman DD. Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents Antimicrobial Agents and Chemotherapy. 37: 1207-1213. PMID 8328771 DOI: 10.1128/Aac.37.6.1207  0.358
1993 Schoenfeld DA, Finkelstein DM, Richman DD. Designing phase II studies of chemotherapy for HIV infection using CD4 as an end-point Aids. 7: 955-958. PMID 8102853 DOI: 10.1097/00002030-199307000-00008  0.385
1993 Kuppermann BD, Petty JG, Richman DD, Mathews WC, Fullerton SC, Rickman LS, Freeman WR. Correlation between CD4+ counts and prevalence of cytomegalovirus retinitis and human immunodeficiency virus-related noninfectious retinal vasculopathy in patients with acquired immunodeficiency syndrome. American Journal of Ophthalmology. 115: 575-82. PMID 8098183 DOI: 10.1097/00006982-199313030-00015  0.402
1993 Skowron G, Bozzette SA, Lim L, Pettinelli CB, Schaumburg HH, Arezzo J, Fischl MA, Powderly WG, Gocke DJ, Richman DD, Pottage JC, Antoniskis D, McKinley GF, Hyslop NE, Ray G, et al. Alternating and intermittent regimens of zidovudine and dideoxycytidine in patients with AIDS or AIDS-related complex. Annals of Internal Medicine. 118: 321-30. PMID 8094279 DOI: 10.7326/0003-4819-118-5-199303010-00001  0.355
1993 Bozzette SA, McCutchan JA, Spector SA, Wright B, Richman DD. A Cross-Sectional Comparison of Persons with Syncytium- and Non-Syncytium-Inducing Human Immunodeficiency Virus Journal of Infectious Diseases. 168: 1374-1379. PMID 7902382 DOI: 10.1093/infdis/168.6.1374  0.411
1993 Richman DD. HIV drug resistance. Annual Review of Pharmacology and Toxicology. 33: 149-64. PMID 7684212 DOI: 10.1146/Annurev.Pa.33.040193.001053  0.517
1993 Meylan PRA, Guatelli JC, Munis JR, Richman DD, Kornbluth RS. Mechanisms for the inhibition of HIV replication by interferons-α, -β, and -γ in primary human macrophages Virology. 193: 138-148. PMID 7679856 DOI: 10.1006/Viro.1993.1110  0.544
1993 Chaisson RE, Moore RD, Richman DD, Keruly J, Creagh T. Incidence and natural history of Mycobacterium avium-complex infections in patients with advanced human immunodeficiency virus disease treated with zidovudine. The Zidovudine Epidemiology Study Group. The American Review of Respiratory Disease. 146: 285-9. PMID 1362634 DOI: 10.1164/Ajrccm/146.2.285  0.413
1993 WU AW, RUBIN HR, MATHEWS WC, BRYSK LM, BOZZETTE SA, HARDY WD, ATKINSON JH, GRANT I, SPECTOR SA, MCCUTCHAN JA, RICHMAN D. Functional Status and Weil-Being in a Placebo-Controlled Trial of Zidovudine in Early Symptomatic HIV Infection Jaids Journal of Acquired Immune Deficiency Syndromes. 6: 452???458. DOI: 10.1097/00126334-199305000-00004  0.388
1992 Meylan PRA, Munis JR, Richman DD, Kornbluth RS. Concurrent human immunodeficiency virus and mycobacterial infection of macrophages in vitro does not reveal any reciprocal effect Journal of Infectious Diseases. 165: 80-86. PMID 1727900 DOI: 10.1093/Infdis/165.1.80  0.584
1992 Richman D, Shih CK, Lowy I, Rose J, Prodanovich P, Goff S, Griffin J. Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture. Proceedings of the National Academy of Sciences of the United States of America. 88: 11241-5. PMID 1722324 DOI: 10.1073/Pnas.88.24.11241  0.45
1992 Munis JR, Kornbluth RS, Guatelli JC, Richman DD. Ordered appearance of human immunodeficiency virus type 1 nucleic acids following high multiplicity infection of macrophages Journal of General Virology. 73: 1899-1906. PMID 1645135 DOI: 10.1099/0022-1317-73-8-1899  0.498
1992 Richman DD. Selection of zidovudine-resistant variants of human immunodeficiency virus by therapy Current Topics in Microbiology and Immunology. 176: 131-142. PMID 1600750 DOI: 10.1007/978-3-642-77011-1_9  0.48
1992 Richman DD. The clinical significance of drug-resistant mutants of human immunodeficiency virus Research in Virology. 143: 130-131. PMID 1594795 DOI: 10.1016/S0923-2516(06)80096-8  0.347
1992 Meylan PRA, Tam EK, Kornbluth RS, Richman DD. HIV infectivity is not augmented by treatment with trypsin, Factor Xa or human mast-cell tryptase [3] Aids. 6: 128-130. PMID 1543555 DOI: 10.1097/00002030-199201000-00019  0.556
1992 Richman DD. HIV drug resistance. Aids Research and Human Retroviruses. 8: 1065-71. PMID 1503820 DOI: 10.1089/Aid.1992.8.1065  0.536
1992 Chaisson RE, Keruly J, Richman DD, Moore RD. Pneumocystis Prophylaxis and Survival in Patients With Advanced Human Immunodeficiency Virus Infection Treated With Zidovudine Archives of Internal Medicine. 152: 2009-2013. PMID 1417373 DOI: 10.1001/Archinte.1992.00400220041007  0.432
1992 Hostetler KY, Richman DD, Carson DA, Stuhmiller LM, Van Wijk GMT, Van den Bosch H. Greatly enhanced inhibition of human immunodeficiency virus type 1 replication in CEM and HT4-6C cells by 3'-deoxythymidine diphosphate dimyristoylglycerol, a lipid prodrug of 3'-deoxythymidine Antimicrobial Agents and Chemotherapy. 36: 2025-2029. PMID 1416896 DOI: 10.1128/Aac.36.9.2025  0.515
1992 Kumar R, Gardner MF, Richman DD, Hostetler KY. Equal inhibition of HIV replication by stereoisomers of phosphatidyl-azidothymidine: Lack of stereospecificity of lysosomal phospholipase A1 Journal of Biological Chemistry. 267: 20288-20292. PMID 1400346  0.305
1992 Hsu MC, Schutt AD, Holly M, Slice LW, Sherman MI, Richman DD, Potash MJ, Volsky DJ. Discovery and characterization of an HIV-1 Tat antagonist. Biochemical Society Transactions. 20: 525-31. PMID 1397654 DOI: 10.1042/Bst0200525  0.582
1992 Gallant JE, Moore RD, Richman DD, Keruly J, Chaisson RE. Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine. The Zidovudine Epidemiology Study Group. The Journal of Infectious Diseases. 166: 1223-7. PMID 1358986 DOI: 10.1093/Infdis/166.6.1223  0.35
1992 Kahn JO, Lagakos SW, Richman DD, Cross A, Pettinelli C, Liou SH, Brown M, Volberding PA, Crumpacker CS, Beall G. A controlled trial comparing continued zidovudine with didanosine in human immunodeficiency virus infection. The NIAID AIDS Clinical Trials Group. The New England Journal of Medicine. 327: 581-7. PMID 1353607 DOI: 10.1056/Nejm199208273270901  0.594
1992 Meng TC, Fischl MA, Boota AM, Spector SA, Bennett D, Bassiakos Y, Lai SH, Wright B, Richman DD. Combination therapy with zidovudine and dideoxycytidine in patients with advanced human immunodeficiency virus infection. A phase I/II study. Annals of Internal Medicine. 116: 13-20. PMID 1345755 DOI: 10.7326/0003-4819-116-1-13  0.495
1992 Bozzette SA, Arcia J, Bartok AE, McGlynn LM, McCutchan JA, Richman DD, Spector SA. Impact of Pneumocystis carinii and cytomegalovirus on the course and outcome of atypical pneumonia in advanced human immunodeficiency virus disease. The Journal of Infectious Diseases. 165: 93-8. PMID 1309375 DOI: 10.1093/infdis/165.1.93  0.359
1992 Richman DD. Emergence of mutant HIV reverse transcriptase conferring resistance to AZT Journal of Enzyme Inhibition and Medicinal Chemistry. 6: 55-64. PMID 1285303 DOI: 10.3109/14756369209041356  0.593
1992 Mayers DL, McCutchan FE, Sanders-Buell EE, Merritt LI, Dilworth S, Fowler AK, Marks CA, Ruiz NM, Richman DD, Roberts CR, Burke DS. Characterization of HIV Isolates Arising After Prolonged Zidovudine Therapy Jaids Journal of Acquired Immune Deficiency Syndromes. 5: 749???759. DOI: 10.1097/00126334-199208000-00001  0.513
1992 Bass HZ, Hardy WD, Mitsuyasu RT, Taylor JMG, Wang YX, Fischl MA, Spector SA, Richman DD, Fahey JL. The Effect of Zidovudine Treatment on Serum Neopterin and ??2-Microglobulin Levels in Mildly Symptomatic, HIV Type 1 Seropositive Individuals Jaids Journal of Acquired Immune Deficiency Syndromes. 5: 215???221. DOI: 10.1097/00126334-199203000-00001  0.391
1992 Moore RD, Keruly J, Richman DD, Creagh-Kirk T, Chaisson RE. Natural history of advanced HIV disease in patients treated with zidovudane Aids. 6: 671-678. DOI: 10.1097/00002030-199207000-00009  0.405
1992 Kahn JO, Lagakos SW, Richman DD, Hirschel B. Changing from zidovudine to didanosine for HIV infection Annals of Internal Medicine. 118: 12.  0.502
1991 O'Shea S, Cordery M, Barrett WY, Richman DD, Bradbeer C, Banatvala JE. HIV excretion patterns and specific antibody responses in body fluids. Journal of Medical Virology. 31: 291-6. PMID 2125310 DOI: 10.1002/Jmv.1890310409  0.499
1991 Richman DD. AZT resistance in isolates of HIV Immunodeficiency Reviews. 2: 315-318. PMID 2059436  0.384
1991 Omary B, Brenner DA, De Grandpre LY, Roebuck KA, Richman DD, Kagnoff MF. HIV-1 infection and expression in human colonic cells: Infection and expression in CD4+ and CD4- cell lines Aids. 5: 275-281. PMID 2059367 DOI: 10.1097/00002030-199103000-00005  0.541
1991 Richman DD. Antiviral therapy of HIV infection Annual Review of Medicine. 42: 69-90. PMID 2035995 DOI: 10.1146/Annurev.Me.42.020191.000441  0.52
1991 López-Galíndez C, Rojas JM, Nájera R, Richman DD, Perucho M. Characterization of genetic variation and 3'-azido-3'-deoxythymidine- resistance mutations of human immunodeficiency virus by the RNase A mismatch cleavage method. Proceedings of the National Academy of Sciences of the United States of America. 88: 4280-4. PMID 2034672 DOI: 10.1073/pnas.88.10.4280  0.437
1991 Terai C, Kornbluth RS, Pauza CD, Richman DD, Carson DA. Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1 Journal of Clinical Investigation. 87: 1710-1715. PMID 2022741 DOI: 10.1172/Jci115188  0.543
1991 Moore RD, Kessler H, Richman DD, Flexner C, Chaisson RE. Non-Hodgkin’s Lymphoma in Patients With Advanced HIV Infection Treated With Zidovudine Jama: the Journal of the American Medical Association. 265: 2208-2211. PMID 2013953 DOI: 10.1001/Jama.1991.03460170062034  0.459
1991 Kagnoff MF, Omary MB, de Grandpre LY, Roebuck KA, Richman DD, Brenner DA. Expression of human immunodeficiency virus-1 in human colonic cells Immunologic Research. 10: 452-455. PMID 1955772 DOI: 10.1007/Bf02919741  0.319
1991 Gingeras TR, Prodanovich P, Latimer T, Guatelli JC, Richman DD, Barringer KJ. Use of self-sustained sequence replication amplification reaction to analyze and detect mutations in zidovudine-resistant human immunodeficiency virus Journal of Infectious Diseases. 164: 1066-1074. PMID 1955709 DOI: 10.1093/Infdis/164.6.1066  0.471
1991 Wu AW, Rubin HR, Mathews WC, Ware JE, Brysk L, Hardy WD, Bozzette SA, Spector SA, Richman DD. A health status questionnaire using 30 items from the medical outcomes study: Preliminary validation in persons with early HIV infection Medical Care. 29: 786-798. PMID 1875745 DOI: 10.1097/00005650-199108000-00011  0.35
1991 Bozzette SA, Larsen RA, Chiu J, Leal MA, Tilles JG, Richman DD, Leedom JM, McCutchan JA. Fluconazole treatment of persistent Cryptococcus neoformans prostatic infection in AIDS. Annals of Internal Medicine. 115: 285-6. PMID 1854112 DOI: 10.7326/0003-4819-115-4-285  0.305
1991 Hsu MC, Schutt AD, Holly M, Slice LW, Sherman MI, Richman DD, Potash MJ, Volsky DJ. Inhibition of HIV replication in acute and chronic infections in vitro by a Tat antagonist Science. 254: 1799-1802. PMID 1763331 DOI: 10.1126/Science.1763331  0.586
1991 Richman DD, Guatelli JC, Grimes J, Tsiatis A, Gingeras T. Detection of mutations associated with zidovudine resistance in human immunodeficiency virus by use of the polymerase chain reaction Journal of Infectious Diseases. 164: 1075-1081. PMID 1720152 DOI: 10.1093/Infdis/164.6.1075  0.314
1991 Hostetler KY, Carson DA, Richman DD. Phosphatidylazidothymidine: Mechanism of antiretroviral action in CEM cells Journal of Biological Chemistry. 266: 11714-11717. PMID 1711037  0.442
1991 Richman D, Rosenthal AS, Skoog M, Eckner RJ, Chou TC, Sabo JP, Merluzzi VJ. BI-RG-587 is active against zidovudine-resistant human immunodeficiency virus type 1 and synergistic with zidovudine. Antimicrobial Agents and Chemotherapy. 35: 305-8. PMID 1708976 DOI: 10.1128/Aac.35.2.305  0.602
1991 Jacobson DL, Allen McCutchan J, Spechko PL, Abramson I, Smith RS, Bartok A, Boss GR, Durand D, Bozzette SA, Spector SA, Richman DD. The evolution of lymphadenopathy and hypergammaglobulinemia are evidence for early and sustained polyclonal B lymphocyte activation during human immunodeficiency virus infection Journal of Infectious Diseases. 163: 240-246. PMID 1671053 DOI: 10.1093/Infdis/163.2.240  0.558
1991 Bozzette SA, Santangelo J, Villasana D, Wright B, Richman DD, Fraser A, Spector SA, Jacobsen C, Hayden E, Schnack J. Peripheral nerve function in persons with asymptomatic or minimally symptomatic hiv disease: Absence of zidovudine neurotoxicity Journal of Acquired Immune Deficiency Syndromes. 4: 851-855. PMID 1654410 DOI: 10.1097/00126334-199109000-00004  0.417
1991 Fischl MA, Richman DD. HIV disease: Pathogenesis and therapy Journal of Acquired Immune Deficiency Syndromes. 4: 1.  0.416
1990 Carson DA, Haertle T, Carrera CJ, Willis EH, Wasson DB, Richman DD. 2-halo-2',3'-dideoxyadenosines: metabolically stable dideoxynucleosides with activity against the human immunodeficiency virus (HIV). Advances in Experimental Medicine and Biology. 395-8. PMID 2610127 DOI: 10.1007/978-1-4684-5676-9_58  0.432
1990 Guatelli JC, Gingeras TR, Richman DD. Alternative splice acceptor utilization during human immunodeficiency virus type 1 infection of cultured cells Journal of Virology. 64: 4093-4098. PMID 2384914 DOI: 10.1128/Jvi.64.9.4093-4098.1990  0.38
1990 Meylan PR, Richman DD, Kornbluth RS. Characterization and growth in human macrophages of Mycobacterium avium complex strains isolated from the blood of patients with acquired immunodeficiency syndrome Infection and Immunity. 58: 2564-2568. PMID 2370109 DOI: 10.1128/Iai.58.8.2564-2568.1990  0.304
1990 Larder BA, Chesebro B, Richman DD. Susceptibilities of zidovudine-susceptible and -resistant human immunodeficiency virus isolates to antiviral agents determined by using a quantitative plaque reduction assay Antimicrobial Agents and Chemotherapy. 34: 436-441. PMID 2334156 DOI: 10.1128/Aac.34.3.436  0.577
1990 Munis JR, Richman DD, Kornbluth RS. Human immunodeficiency virus-1 infection of macrophages in vitro neither induces tumor necrosis factor (TNF)/cachectin gene expression nor alters TNF/cachectin induction by lipopolysaccharide Journal of Clinical Investigation. 85: 591-596. PMID 2298923 DOI: 10.1172/Jci114478  0.411
1990 Pauza CD, Galindo JE, Richman DD. Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persistent human immunodeficiency virus type 1 infection of CEM cells Journal of Experimental Medicine. 172: 1035-1042. PMID 2212939  0.404
1990 Richman DD. Zidovudine resistance of human immunodeficiency virus Reviews of Infectious Diseases. 12: S507-S512. PMID 2201072 DOI: 10.1093/Clinids/12.Supplement_5.S507  0.359
1990 Richman DD. Susceptibility to nucleoside analogues of zidovudine-resistant isolates of human immunodeficiency virus The American Journal of Medicine. 88. PMID 2186629 DOI: 10.1016/0002-9343(90)90414-9  0.345
1990 Kornbluth RS, Munis JR, Oh PS, Meylan PR, Richman DD. Characterization of a macrophage-tropic HIV strain that does not alter macrophage cytokine production yet protects macrophages from superinfection by vesicular stomatitis virus. Aids Research and Human Retroviruses. 6: 1023-6. PMID 2171598 DOI: 10.1089/Aid.1990.6.1023  0.555
1990 Meng TC, Fischl MA, Richman DD. AIDS clinical trials group: Phase I/II study of combination 2′,3′-dideoxycytidine and zidovudine in patients with acquired immunodeficiency syndrome (AIDS) and advanced AIDS-related complex The American Journal of Medicine. 88. PMID 2159707 DOI: 10.1016/0002-9343(90)90419-E  0.504
1990 Bozzette SA, Richman DD. Salvage therapy for zidovudine-intolerant HIV-infected patients with alternating and intermittent regimens of zidovudine and dideoxycytidine The American Journal of Medicine. 88. PMID 2159706 DOI: 10.1016/0002-9343(90)90418-D  0.418
1990 Richman DD, Grimes JM, Lagakos SW. Effect of stage of disease and drug dose on zidovudine susceptibilities of isolates of human immunodeficiency virus Journal of Acquired Immune Deficiency Syndromes. 3: 743-746. PMID 2114476  0.306
1990 Collier AC, Bozzette S, Coombs RW, Causey DM, Schoenfeld DA, Spector SA, Pettinelli CB, Davies G, Richman DD, Leedom JM. A pilot study of low-dose zidovudine in human immunodeficiency virus infection. The New England Journal of Medicine. 323: 1015-21. PMID 1977080 DOI: 10.1056/Nejm199010113231502  0.554
1990 Fischl MA, Parker CB, Pettinelli C, Wulfsohn M, Hirsch MS, Collier AC, Antoniskis D, Ho M, Richman DD, Fuchs E, Merigan TC, Reichman RC, Gold J, Steigbigel N, Leoung GS, et al. A randomized controlled trial of a reduced daily dose of zidovudine in patients with the acquired immunodeficiency syndrome New England Journal of Medicine. 323: 1009-1014. PMID 1977079 DOI: 10.1056/Nejm199010113231501  0.398
1990 Zarling JM, Moran PA, Haffar O, Sias J, Richman DD, Spina CA, Myers DE, Kuebelbeck V, Ledbetter JA, Uckun FM. Inhibition of HIV replication by pokeweed antiviral protein targeted to CD4+ cells by monoclonal antibodies Nature. 347: 92-95. PMID 1975641 DOI: 10.1038/347092A0  0.496
1990 Fischl MA, Richman DD, Hansen N, Collier AC, Carey JT, Para MF, Hardy WD, Dolin R, Powderly WG, Allan JD, Wong B, Merigan TC, McAuliffe VJ, Hyslop NE, Rhame FS, et al. The safety and efficacy of zidovudine (AZT) in the treatment of subjects with mildly symptomatic human immunodeficiency virus type 1 (HIV) infection a double-blind, placebo-controlled trial Annals of Internal Medicine. 112: 727-737. PMID 1970466 DOI: 10.7326/0003-4819-112-10-727  0.427
1990 Frank KB, Connell EV, Holman MJ, Huryn DM, Sluboski BC, Tam SY, Todaro LJ, Weigele M, Richman DD, Mitsuya H. Anabolism and mechanism of action of Ro24-5098, an isomer of 2',3'-dideoxyadenosine (ddA) with anti-HIV activity. Annals of the New York Academy of Sciences. 616: 408-14. PMID 1706575 DOI: 10.1111/J.1749-6632.1990.Tb17860.X  0.5
1990 Gingeras TR, Richman DD, Kwoh DY, Guatelli JC. Methodologies for in vitro nucleic acid amplification and their applications Veterinary Microbiology. 24: 235-251. PMID 1701942 DOI: 10.1016/0378-1135(90)90174-T  0.331
1990 Kornbluth RS, Oh PS, Munis JR, Cleveland PH, Richman DD. The role of interferons in the control of HIV replication in macrophages. Clinical Immunology and Immunopathology. 54: 200-19. PMID 1688522 DOI: 10.1016/0090-1229(90)90082-2  0.598
1990 HURYN DM, SLUBOSKI BC, TAM SY, TODARO LJ, WEIGELE M, SIM IS, FRANK KB, RICHMAN DD, MITSUYA H, BRODER S. Synthesis and Anti-HIV Activity of a Novel Series of Isomeric Dideoxynucleosides Annals of the New York Academy of Sciences. 616: 530-534. DOI: 10.1111/j.1749-6632.1990.tb17885.x  0.419
1990 Huryn DM, Sluboski BC, Tam SY, Todaro LJ, Weigele M, Sim IS, Frank KB, Richman DD, Mitsuya H, Broder S. Synthesis and anti-HIV activity of a novel series of isomeric dideoxynucleosides Annals of the New York Academy of Sciences. 616: 530-534. DOI: 10.1111/J.1749-6632.1990.Tb17885.X  0.515
1990 Fischl MA, Richman DD, Andrews JC. In Reply Jama: the Journal of the American Medical Association. 263: 1635-1636. DOI: 10.1001/Jama.1990.03440120057032  0.315
1989 Richman DD. Public access to experimental drug therapy: Aids raises yet another conflict between freedom of the individual and welfare of the individual and public Journal of Infectious Diseases. 159: 412-415. PMID 2915164 DOI: 10.1093/Infdis/159.3.412  0.34
1989 Bentin J, Tsoukas CD, McCutchan JA, Spector SA, Richman DD, Vaughan JH. Impairment in T-lymphocyte responses during early infection with the human immunodeficiency virus Journal of Clinical Immunology. 9: 159-168. PMID 2785531 DOI: 10.1007/Bf00916944  0.444
1989 Guatelli JC, Gingeras TR, Richman DD. Nucleic acid amplification in vitro: Detection of sequences with low copy numbers and application to diagnosis of human immunodeficiency virus type 1 infection Clinical Microbiology Reviews. 2: 217-226. PMID 2650862 DOI: 10.1128/Cmr.2.2.217  0.36
1989 Woolf NK, Koehrn FJ, Harris JP, Richman DD. Congenital cytomegalovirus labyrinthitis and sensorineural hearing loss in guinea pigs. The Journal of Infectious Diseases. 160: 929-37. PMID 2555420 DOI: 10.1093/Infdis/160.6.929  0.329
1989 Mosier DE, Gulizia RJ, Baird SM, Spector S, Spector D, Kipps TJ, Fox RI, Carson DA, Cooper N, Richman DD. Studies of HIV infection and the development of Epstein-Barr virus-related B cell lymphomas following transfer of human lymphocytes to mice with severe combined immunodeficiency. Current Topics in Microbiology and Immunology. 152: 195-9. PMID 2553338 DOI: 10.1007/978-3-642-74974-2_23  0.401
1989 Spector SA, Kennedy C, McCutchan JA, Bozzette SA, Straube RG, Connor JD, Richman DD. The Antiviral Effect of Zidovudine and Ribavirin in Clinical Trials and The Use of p24 Antigen Levels as a Virologic Marker Journal of Infectious Diseases. 159: 822-828. PMID 2496173 DOI: 10.1093/Infdis/159.5.822  0.46
1989 Larder BA, Darby G, Richman DD. HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy Science. 243: 1731-1734. PMID 2467383 DOI: 10.1126/Science.2467383  0.528
1989 Kornbluth RS, Oh PS, Munis JR, Cleveland PH, Richman DD. Interferons and bacterial lipopolysaccharide protect macrophages from productive infection by human immunodeficiency virus in vitro. The Journal of Experimental Medicine. 169: 1137-51. PMID 2466937 DOI: 10.1084/Jem.169.3.1137  0.527
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