Karl Munger - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology, Virology Biology, Epidemiology

153 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Romero-Masters JC, Muehlbauer LK, Hayes M, Grace M, Shishkova E, Coon JJ, Munger K, Lambert PF. MmuPV1 E6 induces cell proliferation and other hallmarks of cancer. Mbio. e0245823. PMID 37905801 DOI: 10.1128/mbio.02458-23  0.354
2023 Gelbard MK, Munger K. Human papillomaviruses: Knowns, mysteries, and unchartered territories. Journal of Medical Virology. 95: e29191. PMID 37861365 DOI: 10.1002/jmv.29191  0.552
2023 Wu SC, Grace M, Munger K. The HPV8 E6 protein targets the Hippo and Wnt signaling pathways as part of its arsenal to restrain keratinocyte differentiation. Mbio. e0155623. PMID 37676018 DOI: 10.1128/mbio.01556-23  0.533
2023 Romero-Masters JC, Grace M, Lee D, Lei J, DePamphilis M, Buehler D, Hu R, Ward-Shaw E, Blaine-Sauer S, Lavoie N, White EA, Munger K, Lambert PF. MmuPV1 E7's interaction with PTPN14 delays Epithelial differentiation and contributes to virus-induced skin disease. Plos Pathogens. 19: e1011215. PMID 37036883 DOI: 10.1371/journal.ppat.1011215  0.467
2022 Romero-Masters JC, Lambert PF, Munger K. Molecular Mechanisms of MmuPV1 E6 and E7 and Implications for Human Disease. Viruses. 14. PMID 36298698 DOI: 10.3390/v14102138  0.557
2021 Mason D, Munger K, Tran N. The dynamic interactome of microRNAs and the human papillomavirus in head and neck cancers. Current Opinion in Virology. 51: 87-95. PMID 34627109 DOI: 10.1016/j.coviro.2021.09.013  0.406
2021 Wei T, Grace M, Uberoi A, Romero-Masters JC, Lee D, Lambert PF, Munger K. The Mus musculus Papillomavirus Type 1 E7 Protein Binds to the Retinoblastoma Tumor Suppressor: Implications for Viral Pathogenesis. Mbio. 12: e0227721. PMID 34465025 DOI: 10.1128/mBio.02277-21  0.465
2020 Hatterschide J, Brantly AC, Grace M, Munger K, White EA. A conserved amino acid in the C-terminus of HPV E7 mediates binding to PTPN14 and repression of epithelial differentiation. Journal of Virology. PMID 32581101 DOI: 10.1128/Jvi.01024-20  0.616
2020 Sharma S, Munger K. Expression of the Long Noncoding RNA DINO in Human Papillomavirus-Positive Cervical Cancer Cells Reactivates the Dormant TP53 Tumor Suppressor through ATM/CHK2 Signaling. Mbio. 11. PMID 32546626 DOI: 10.1128/Mbio.01190-20  0.609
2020 Sharma S, Munger K. The Role of Long Noncoding RNAs in Human Papillomavirus-associated Pathogenesis. Pathogens (Basel, Switzerland). 9. PMID 32326624 DOI: 10.3390/Pathogens9040289  0.564
2020 Sharma S, Munger K. KDM6A mediated expression of the long noncoding RNA DINO causes TP53 tumor suppressor stabilization in Human Papillomavirus type 16 E7 expressing cells. Journal of Virology. PMID 32269126 DOI: 10.1128/Jvi.02178-19  0.619
2019 Hatterschide J, Bohidar AE, Grace M, Nulton TJ, Kim HW, Windle B, Morgan IM, Munger K, White EA. PTPN14 degradation by high-risk human papillomavirus E7 limits keratinocyte differentiation and contributes to HPV-mediated oncogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30894485 DOI: 10.1073/Pnas.1819534116  0.625
2018 Gaglia MM, Munger K. More than just oncogenes: mechanisms of tumorigenesis by human viruses. Current Opinion in Virology. 32: 48-59. PMID 30268926 DOI: 10.1016/J.Coviro.2018.09.003  0.437
2018 Meyers JM, Grace M, Uberoi A, Lambert PF, Munger K. Inhibition of TGF-β and NOTCH Signaling by Cutaneous Papillomaviruses. Frontiers in Microbiology. 9: 389. PMID 29568286 DOI: 10.3389/Fmicb.2018.00389  0.517
2018 McBride AA, Münger K. Expert Views on HPV Infection. Viruses. 10. PMID 29495253 DOI: 10.3390/V10020094  0.517
2018 Sharma S, Munger K. Expression of the cervical carcinoma expressed PCNA regulatory (CCEPR) long noncoding RNA is driven by the human papillomavirus E6 protein and modulates cell proliferation independent of PCNA. Virology. 518: 8-13. PMID 29427865 DOI: 10.1016/J.Virol.2018.01.031  0.587
2018 Wallace NA, Münger K. The curious case of APOBEC3 activation by cancer-associated human papillomaviruses. Plos Pathogens. 14: e1006717. PMID 29324878 DOI: 10.1371/Journal.Ppat.1006717  0.343
2017 Chiang C, Pauli EK, Biryukov J, Feister KF, Meng M, White EA, Münger K, Howley PM, Meyers C, Gack MU. The human papillomavirus E6 oncoprotein targets USP15 and TRIM25 to suppress RIG-I-mediated innate immune signaling. Journal of Virology. PMID 29263274 DOI: 10.1128/Jvi.01737-17  0.568
2017 Soto DR, Barton C, Munger K, McLaughlin-Drubin ME. KDM6A addiction of cervical carcinoma cell lines is triggered by E7 and mediated by p21CIP1 suppression of replication stress. Plos Pathogens. 13: e1006661. PMID 28968467 DOI: 10.1371/Journal.Ppat.1006661  0.571
2017 Soto DR, Barton C, Munger K, McLaughlin-Drubin ME. KDM6A addiction of cervical carcinoma cell lines is triggered by E7 and mediated by p21CIP1 suppression of replication stress. Plos Pathogens. 13: e1006661. PMID 28968467 DOI: 10.1371/journal.ppat.1006661  0.49
2017 White EA, Munger K. Crowd Control: E7 Conservation Is the Key to Cancer. Cell. 170: 1057-1059. PMID 28886377 DOI: 10.1016/J.Cell.2017.08.033  0.605
2017 Miller AK, Munger K, Adler FR. A Mathematical Model of Cell Cycle Dysregulation Due to Human Papillomavirus Infection. Bulletin of Mathematical Biology. PMID 28608043 DOI: 10.1007/S11538-017-0299-9  0.572
2017 Harden ME, Munger K. Human papillomavirus molecular biology. Mutation Research. 772: 3-12. PMID 28528688 DOI: 10.1016/J.Mrrev.2016.07.002  0.431
2017 Harden ME, Munger K. Human papillomavirus 16 E6 and E7 oncoprotein expression alters microRNA expression in extracellular vesicles. Virology. 508: 63-69. PMID 28500882 DOI: 10.1016/J.Virol.2017.05.005  0.472
2017 E Harden M, Munger K. Perturbation of DROSHA and DICER expression by human papillomavirus 16 oncoproteins. Virology. 507: 192-198. PMID 28448850 DOI: 10.1016/J.Virol.2017.04.022  0.619
2017 Meyers JM, Uberoi A, Grace M, Lambert PF, Munger K. Cutaneous HPV8 and MmuPV1 E6 Proteins Target the NOTCH and TGF-β Tumor Suppressors to Inhibit Differentiation and Sustain Keratinocyte Proliferation. Plos Pathogens. 13: e1006171. PMID 28107544 DOI: 10.1371/Journal.Ppat.1006171  0.599
2017 Harden ME, Prasad N, Griffiths A, Munger K. Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 Oncoproteins. Mbio. 8. PMID 28049151 DOI: 10.1128/Mbio.02170-16  0.564
2016 Grace M, Munger K. Proteomic analysis of the gamma human papillomavirus type 197 E6 and E7 associated cellular proteins. Virology. 500: 71-81. PMID 27771561 DOI: 10.1016/J.Virol.2016.10.010  0.63
2016 White EA, Münger K, Howley PM. High-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation. Mbio. 7. PMID 27651363 DOI: 10.1128/Mbio.01530-16  0.596
2016 Munger K. Viruses and Cancer: An Accidental Journey. Plos Pathogens. 12: e1005573. PMID 27606603 DOI: 10.1371/Journal.Ppat.1005573  0.506
2016 Münger K. Abstract IA27: Perturbation of host cellular regulatory networks by human papillomaviruses Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-Ia27  0.656
2015 Munger K, Jones DL. Human papillomavirus carcinogenesis: an identity crisis in the retinoblastoma tumor suppressor pathway. Journal of Virology. 89: 4708-11. PMID 25673729 DOI: 10.1128/Jvi.03486-14  0.4
2014 Meyers JM, Munger K. The viral etiology of skin cancer. The Journal of Investigative Dermatology. 134: E29-32. PMID 25302471 DOI: 10.1038/Skinbio.2014.6  0.35
2014 Mesri EA, Feitelson MA, Munger K. Human viral oncogenesis: a cancer hallmarks analysis. Cell Host & Microbe. 15: 266-82. PMID 24629334 DOI: 10.1016/J.Chom.2014.02.011  0.43
2014 Munger K. Are selective estrogen receptor modulators (SERMs) a therapeutic option for HPV-associated cervical lesions and cancers? The American Journal of Pathology. 184: 358-61. PMID 24345353 DOI: 10.1016/J.Ajpath.2013.11.005  0.511
2014 McLaughlin-Drubin ME, Munger K. Papillomaviruses Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00007-6  0.463
2014 Spangle JM, Chen AA, Munger K. Human papillomavirus: Pathogenesis and host immune response Viruses and Human Cancer. 167-197. DOI: 10.1007/978-1-4939-0870-7_8  0.821
2013 Munger K, Gwin TK, McLaughlin-Drubin ME. p16 in HPV-associated cancers. Oncotarget. 4: 1864-5. PMID 24192550 DOI: 10.18632/Oncotarget.1523  0.622
2013 Yu Y, Munger K. Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis. Virology. 446: 251-9. PMID 24074588 DOI: 10.1016/J.Virol.2013.08.013  0.743
2013 Mack HI, Munger K. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines. Virology. 446: 9-16. PMID 24074562 DOI: 10.1016/J.Virol.2013.07.009  0.536
2013 McLaughlin-Drubin ME, Park D, Munger K. Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines. Proceedings of the National Academy of Sciences of the United States of America. 110: 16175-80. PMID 24046371 DOI: 10.1073/Pnas.1310432110  0.514
2013 Roman A, Munger K. The papillomavirus E7 proteins. Virology. 445: 138-68. PMID 23731972 DOI: 10.1016/J.Virol.2013.04.013  0.478
2013 McLaughlin-Drubin ME, Munger K. Biochemical and functional interactions of human papillomavirus proteins with polycomb group proteins. Viruses. 5: 1231-49. PMID 23673719 DOI: 10.3390/V5051231  0.546
2013 Spangle JM, Munger K. The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species. Plos Pathogens. 9: e1003237. PMID 23516367 DOI: 10.1371/Journal.Ppat.1003237  0.815
2013 Meyers JM, Spangle JM, Munger K. The human papillomavirus type 8 E6 protein interferes with NOTCH activation during keratinocyte differentiation. Journal of Virology. 87: 4762-7. PMID 23365452 DOI: 10.1128/Jvi.02527-12  0.817
2012 Mack HI, Munger K. Modulation of autophagy-like processes by tumor viruses. Cells. 1: 204-47. PMID 24710474 DOI: 10.3390/Cells1030204  0.347
2012 Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, et al. Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature. 487: 491-5. PMID 22810586 DOI: 10.1038/Nature11288  0.75
2012 Gulbahce N, Yan H, Dricot A, Padi M, Byrdsong D, Franchi R, Lee DS, Rozenblatt-Rosen O, Mar JC, Calderwood MA, Baldwin A, Zhao B, Santhanam B, Braun P, Simonis N, et al. Viral perturbations of host networks reflect disease etiology. Plos Computational Biology. 8: e1002531. PMID 22761553 DOI: 10.1371/Journal.Pcbi.1002531  0.632
2012 Yu Y, Munger K. Human papillomavirus type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint. Virology. 432: 120-6. PMID 22748180 DOI: 10.1016/J.Virol.2012.06.006  0.751
2012 Herfs M, Yamamoto Y, Laury A, Wang X, Nucci MR, McLaughlin-Drubin ME, Münger K, Feldman S, McKeon FD, Xian W, Crum CP. A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 10516-21. PMID 22689991 DOI: 10.1073/Pnas.1202684109  0.582
2012 McLaughlin-Drubin ME, Meyers J, Munger K. Cancer associated human papillomaviruses. Current Opinion in Virology. 2: 459-66. PMID 22658985 DOI: 10.1016/J.Coviro.2012.05.004  0.602
2012 Spangle JM, Ghosh-Choudhury N, Munger K. Activation of cap-dependent translation by mucosal human papillomavirus E6 proteins is dependent on the integrity of the LXXLL binding motif. Journal of Virology. 86: 7466-72. PMID 22553330 DOI: 10.1128/Jvi.00487-12  0.816
2012 Xylas J, McLaughlin-Drubin M, Münger K, Georgakoudi I. Elucidating metabolic, subcellular, and tissue-level changes induced by HPV-related oncoproteins Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2012.Bsu3A.33  0.524
2012 Xylas J, McLaughlin-Drubin M, Munger K, Georgakoudi I. Identification of molecular origins of optical biomarkers of precancerous changes Biomedical Optics, Biomed 2012 0.325
2011 McLaughlin-Drubin ME, Crum CP, Münger K. Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming. Proceedings of the National Academy of Sciences of the United States of America. 108: 2130-5. PMID 21245294 DOI: 10.1073/Pnas.1009933108  0.628
2011 Hellner K, Münger K. Human papillomaviruses as therapeutic targets in human cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1785-94. PMID 21220591 DOI: 10.1200/Jco.2010.28.2186  0.575
2010 Zhou X, Münger K. Clld7, a candidate tumor suppressor on chromosome 13q14, regulates pathways of DNA damage/repair and apoptosis. Cancer Research. 70: 9434-43. PMID 20926398 DOI: 10.1158/0008-5472.Can-10-1960  0.344
2010 Spangle JM, Münger K. The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis. Journal of Virology. 84: 9398-407. PMID 20631133 DOI: 10.1128/Jvi.00974-10  0.819
2010 Baldwin A, Grueneberg DA, Hellner K, Sawyer J, Grace M, Li W, Harlow E, Munger K. Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3. Proceedings of the National Academy of Sciences of the United States of America. 107: 12463-8. PMID 20616055 DOI: 10.1073/Pnas.1007462107  0.444
2010 Lowy DR, Munger K. Prognostic implications of HPV in oropharyngeal cancer. The New England Journal of Medicine. 363: 82-4. PMID 20530315 DOI: 10.1056/NEJMe1003607  0.466
2009 Kamil JP, Hume AJ, Jurak I, Münger K, Kalejta RF, Coen DM. Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 106: 16823-8. PMID 19805380 DOI: 10.1073/Pnas.0901521106  0.443
2009 Korzeniewski N, Zheng L, Cuevas R, Parry J, Chatterjee P, Anderton B, Duensing A, Münger K, Duensing S. Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels. Cancer Research. 69: 6668-75. PMID 19679553 DOI: 10.1158/0008-5472.Can-09-1284  0.379
2009 Hellner K, Mar J, Fang F, Quackenbush J, Münger K. HPV16 E7 oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesenchymal transition. Virology. 391: 57-63. PMID 19552933 DOI: 10.1016/J.Virol.2009.05.036  0.601
2009 McLaughlin-Drubin ME, Münger K. Oncogenic activities of human papillomaviruses. Virus Research. 143: 195-208. PMID 19540281 DOI: 10.1016/J.Virusres.2009.06.008  0.617
2009 Zhou X, Spangle JM, Münger K. Expression of a viral oncoprotein in normal human epithelial cells triggers an autophagy-related process: is autophagy an "Achilles' heel" of human cancers? Autophagy. 5: 578-9. PMID 19333004 DOI: 10.4161/Auto.5.4.8367  0.777
2009 Zhou X, Münger K. Expression of the human papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell death in response to growth factor deprivation. Virology. 385: 192-7. PMID 19135224 DOI: 10.1016/J.Virol.2008.12.003  0.617
2009 Nguyen CL, Münger K. Human papillomavirus E7 protein deregulates mitosis via an association with nuclear mitotic apparatus protein 1. Journal of Virology. 83: 1700-7. PMID 19052088 DOI: 10.1128/Jvi.01971-08  0.629
2009 McLaughlin-Drubin ME, Münger K. The human papillomavirus E7 oncoprotein. Virology. 384: 335-44. PMID 19007963 DOI: 10.1016/J.Virol.2008.10.006  0.626
2008 Nguyen CL, McLaughlin-Drubin ME, Münger K. Delocalization of the microtubule motor Dynein from mitotic spindles by the human papillomavirus E7 oncoprotein is not sufficient for induction of multipolar mitoses. Cancer Research. 68: 8715-22. PMID 18974113 DOI: 10.1158/0008-5472.Can-08-1303  0.578
2008 Grueneberg DA, Degot S, Pearlberg J, Li W, Davies JE, Baldwin A, Endege W, Doench J, Sawyer J, Hu Y, Boyce F, Xian J, Munger K, Harlow E. Kinase requirements in human cells: I. Comparing kinase requirements across various cell types. Proceedings of the National Academy of Sciences of the United States of America. 105: 16472-7. PMID 18948591 DOI: 10.1073/Pnas.0808019105  0.328
2008 Nguyen CL, Münger K. Direct association of the HPV16 E7 oncoprotein with cyclin A/CDK2 and cyclin E/CDK2 complexes. Virology. 380: 21-5. PMID 18718623 DOI: 10.1016/J.Virol.2008.07.017  0.572
2008 McLaughlin-Drubin M, Münger K. The human papillomavirus type 8 E2 gene encodes a transforming activity sufficient for skin tumor formation in transgenic mice. The Journal of Investigative Dermatology. 128: 2142-4. PMID 18695686 DOI: 10.1038/Jid.2008.217  0.525
2008 McLaughlin-Drubin ME, Huh KW, Münger K. Human papillomavirus type 16 E7 oncoprotein associates with E2F6. Journal of Virology. 82: 8695-705. PMID 18579589 DOI: 10.1128/Jvi.00579-08  0.564
2008 McLaughlin-Drubin ME, Munger K. Viruses associated with human cancer. Biochimica Et Biophysica Acta. 1782: 127-50. PMID 18201576 DOI: 10.1016/J.Bbadis.2007.12.005  0.384
2008 Mujat C, Greiner C, Baldwin A, Levitt JM, Tian F, Stucenski LA, Hunter M, Kim YL, Backman V, Feld M, Münger K, Georgakoudi I. Endogenous optical biomarkers of normal and human papillomavirus immortalized epithelial cells. International Journal of Cancer. Journal International Du Cancer. 122: 363-71. PMID 17935126 DOI: 10.1002/Ijc.23120  0.34
2008 Nyga R, Dhennin-Duthille I, Yahiaoui S, Munger K, Regnier A, Gouilleux-Gruart V, Lassoued K, Gouilleux F. Identification of hTid1 as a Molecular Partner and a Negative Regulator of the Transcription Factor Stat5B Blood. 112: 3855-3855. DOI: 10.1182/Blood.V112.11.3855.3855  0.358
2007 Nguyen CL, Eichwald C, Nibert ML, Münger K. Human papillomavirus type 16 E7 oncoprotein associates with the centrosomal component gamma-tubulin. Journal of Virology. 81: 13533-43. PMID 17913829 DOI: 10.1128/Jvi.01669-07  0.619
2007 Mangold U, Hayakawa H, Coughlin M, Münger K, Zetter BR. Antizyme, a mediator of ubiquitin-independent proteasomal degradation and its inhibitor localize to centrosomes and modulate centriole amplification. Oncogene. 27: 604-13. PMID 17667942 DOI: 10.1038/Sj.Onc.1210685  0.335
2007 Huh K, Zhou X, Hayakawa H, Cho JY, Libermann TA, Jin J, Harper JW, Munger K. Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor. Journal of Virology. 81: 9737-47. PMID 17609271 DOI: 10.1128/Jvi.00881-07  0.632
2006 Levitt JM, Baldwin A, Papadakis A, Puri S, Xylas J, Münger K, Georgakoudi I. Intrinsic fluorescence and redox changes associated with apoptosis of primary human epithelial cells. Journal of Biomedical Optics. 11: 064012. PMID 17212535 DOI: 10.1117/1.2401149  0.313
2006 Baldwin A, Huh KW, Münger K. Human papillomavirus E7 oncoprotein dysregulates steroid receptor coactivator 1 localization and function. Journal of Virology. 80: 6669-77. PMID 16775354 DOI: 10.1128/Jvi.02497-05  0.619
2005 Georgakoudi I, Levitt J, Baldwin A, Papadakis A, Münger K. Intrinsic fluorescence changes associated with apoptosis of human epithelial keratinocytes. Gynecologic Oncology. 99: S54-7. PMID 16419185 DOI: 10.1016/J.Ygyno.2005.07.043  0.306
2005 DeMasi J, Huh KW, Nakatani Y, Münger K, Howley PM. Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding. Proceedings of the National Academy of Sciences of the United States of America. 102: 11486-91. PMID 16081543 DOI: 10.1073/Pnas.0505322102  0.487
2005 Huh KW, DeMasi J, Ogawa H, Nakatani Y, Howley PM, Münger K. Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600. Proceedings of the National Academy of Sciences of the United States of America. 102: 11492-7. PMID 16061792 DOI: 10.1073/Pnas.0505337102  0.584
2005 Münger K. Human Papillomaviruses and Cervical Cancer Retrovirology. 2: 1-1. DOI: 10.1186/1742-4690-2-S1-S48  0.464
2004 Tarunina M, Alger L, Chu G, Munger K, Gudkov A, Jat PS. Functional genetic screen for genes involved in senescence: role of Tid1, a homologue of the Drosophila tumor suppressor l(2)tid, in senescence and cell survival. Molecular and Cellular Biology. 24: 10792-801. PMID 15572682 DOI: 10.1128/Mcb.24.24.10792-10801.2004  0.44
2004 Münger K, Baldwin A, Edwards KM, Hayakawa H, Nguyen CL, Owens M, Grace M, Huh K. Mechanisms of human papillomavirus-induced oncogenesis. Journal of Virology. 78: 11451-60. PMID 15479788 DOI: 10.1128/Jvi.78.21.11451-11460.2004  0.358
2004 Edwards KM, Münger K. Depletion of physiological levels of the human TID1 protein renders cancer cell lines resistant to apoptosis mediated by multiple exogenous stimuli. Oncogene. 23: 8419-31. PMID 15156195 DOI: 10.1038/Sj.Onc.1207732  0.386
2004 Edwards KM, Münger K. Make WARTS, not cancer! Oncogene. 23: 5263-5. PMID 15122320 DOI: 10.1038/Sj.Onc.1207686  0.356
2004 Eichten A, Rud DS, Grace M, Piboonniyom SO, Zacny V, Münger K. Molecular pathways executing the "trophic sentinel" response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation. Virology. 319: 81-93. PMID 14967490 DOI: 10.1016/J.Virol.2003.11.008  0.56
2004 Hasskarl J, Duensing S, Manuel E, Münger K. The helix-loop-helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers. Oncogene. 23: 1930-8. PMID 14755252 DOI: 10.1038/Sj.Onc.1207310  0.37
2004 Duensing S, Münger K. Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins. International Journal of Cancer. 109: 157-62. PMID 14750163 DOI: 10.1002/Ijc.11691  0.588
2004 Papadakis A, Georgakoudi I, Baldwin A, Münger K. Spectral fluorescence imaging for the characterization of HPV16 transfected cells Biosilico. DOI: 10.1364/Bio.2004.Sd1  0.458
2003 Balsitis SJ, Sage J, Duensing S, Münger K, Jacks T, Lambert PF. Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Molecular and Cellular Biology. 23: 9094-103. PMID 14645521 DOI: 10.1128/Mcb.23.24.9094-9103.2003  0.499
2003 Duensing S, Münger K. Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins. Progress in Cell Cycle Research. 5: 383-91. PMID 14593733  0.499
2003 Duensing S, Münger K. Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members. Journal of Virology. 77: 12331-5. PMID 14581569 DOI: 10.1128/Jvi.77.22.12331-12335.2003  0.592
2003 Kleine-Lowinski K, Rheinwald JG, Fichorova RN, Anderson DJ, Basile J, Münger K, Daly CM, Rösl F, Rollins BJ. Selective suppression of monocyte chemoattractant protein-1 expression by human papillomavirus E6 and E7 oncoproteins in human cervical epithelial and epidermal cells. International Journal of Cancer. Journal International Du Cancer. 107: 407-15. PMID 14506741 DOI: 10.1002/Ijc.11411  0.608
2003 Riley RR, Duensing S, Brake T, Münger K, Lambert PF, Arbeit JM. Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Research. 63: 4862-71. PMID 12941807  0.426
2003 Syken J, Macian F, Agarwal S, Rao A, Münger K. TID1, a mammalian homologue of the drosophila tumor suppressor lethal(2) tumorous imaginal discs, regulates activation-induced cell death in Th2 cells. Oncogene. 22: 4636-41. PMID 12879007 DOI: 10.1038/Sj.Onc.1206569  0.33
2003 Duensing S, Münger K. Centrosomes, genomic instability, and cervical carcinogenesis. Critical Reviews in Eukaryotic Gene Expression. 13: 9-23. PMID 12839094 DOI: 10.1615/Critreveukaryotgeneexpr.V13.I1.20  0.619
2003 Munger K. Clefts, grooves, and (small) pockets: the structure of the retinoblastoma tumor suppressor in complex with its cellular target E2F unveiled. Proceedings of the National Academy of Sciences of the United States of America. 100: 2165-7. PMID 12606716 DOI: 10.1073/Pnas.0630419100  0.32
2003 Genther SM, Sterling S, Duensing S, Münger K, Sattler C, Lambert PF. Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle. Journal of Virology. 77: 2832-42. PMID 12584306 DOI: 10.1128/Jvi.77.5.2832-2842.2003  0.575
2003 Piboonniyom SO, Duensing S, Swilling NW, Hasskarl J, Hinds PW, Münger K. Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability. Cancer Research. 63: 476-83. PMID 12543805  0.499
2002 Duensing S, Münger K. The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Research. 62: 7075-82. PMID 12460929  0.538
2002 Münger K, Howley PM. Human papillomavirus immortalization and transformation functions. Virus Research. 89: 213-28. PMID 12445661 DOI: 10.1016/S0168-1702(02)00190-9  0.635
2002 Duensing S, Münger K. Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability. Oncogene. 21: 6241-8. PMID 12214255 DOI: 10.1038/Sj.Onc.1205709  0.628
2002 Hasskarl J, Münger K. Id proteins--tumor markers or oncogenes? Cancer Biology & Therapy. 1: 91-6. PMID 12170780 DOI: 10.4161/Cbt.50  0.346
2002 Eichten A, Westfall M, Pietenpol JA, Münger K. Stabilization and functional impairment of the tumor suppressor p53 by the human papillomavirus type 16 E7 oncoprotein. Virology. 295: 74-85. PMID 12033767 DOI: 10.1006/Viro.2002.1375  0.492
2002 Münger K. The role of human papillomaviruses in human cancers. Frontiers in Bioscience : a Journal and Virtual Library. 7: d641-9. PMID 11861215 DOI: 10.2741/A800  0.63
2002 Piboonniyom SO, Timmermann S, Hinds P, Münger K. Aberrations in the MTS1 tumor suppressor locus in oral squamous cell carcinoma lines preferentially affect the INK4A gene and result in increased cdk6 activity. Oral Oncology. 38: 179-86. PMID 11854066 DOI: 10.1016/S1368-8375(01)00042-2  0.364
2002 Münger K. Disruption of oncogene/tumor suppressor networks during human carcinogenesis. Cancer Investigation. 20: 71-81. PMID 11853005 DOI: 10.1081/Cnv-120000369  0.407
2001 Münger K, Basile JR, Duensing S, Eichten A, Gonzalez SL, Grace M, Zacny VL. Biological activities and molecular targets of the human papillomavirus E7 oncoprotein. Oncogene. 20: 7888-98. PMID 11753671 DOI: 10.1038/Sj.Onc.1204860  0.646
2001 Jiang X, Wilford C, Duensing S, Munger K, Jones G, Jones D. Participation of Survivin in mitotic and apoptotic activities of normal and tumor-derived cells. Journal of Cellular Biochemistry. 83: 342-54. PMID 11573250 DOI: 10.1002/Jcb.1228  0.347
2001 Duensing S, Duensing A, Flores ER, Do A, Lambert PF, Münger K. Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes. Journal of Virology. 75: 7712-6. PMID 11462043 DOI: 10.1128/Jvi.75.16.7712-7716.2001  0.612
2001 Gonzalez SL, Stremlau M, He X, Basile JR, Münger K. Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7. Journal of Virology. 75: 7583-91. PMID 11462030 DOI: 10.1128/Jvi.75.16.7583-7591.2001  0.553
2001 Thompson DA, Zacny V, Belinsky GS, Classon M, Jones DL, Schlegel R, Münger K. The HPV E7 oncoprotein inhibits tumor necrosis factor α-mediated apoptosis in normal human fibroblasts Oncogene. 20: 3629-3640. PMID 11439326 DOI: 10.1038/Sj.Onc.1204483  0.454
2001 Keating JT, Cviko A, Riethdorf S, Riethdorf L, Quade BJ, Sun D, Duensing S, Sheets EE, Munger K, Crum CP. Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia. The American Journal of Surgical Pathology. 25: 884-891. PMID 11420459 DOI: 10.1097/00000478-200107000-00006  0.49
2001 Duensing S, Münger K. Centrosome abnormalities, genomic instability and carcinogenic progression. Biochimica Et Biophysica Acta. 1471. PMID 11342187 DOI: 10.1016/S0304-419X(00)00025-1  0.377
2001 Basile JR, Zacny V, Münger K. The Cytokines Tumor Necrosis Factor-α (TNF-α) and TNF-related Apoptosis-inducing Ligand Differentially Modulate Proliferation and Apoptotic Pathways in Human Keratinocytes Expressing the Human Papillomavirus-16 E7 Oncoprotein Journal of Biological Chemistry. 276: 22522-22528. PMID 11306566 DOI: 10.1074/Jbc.M010505200  0.493
2000 Munger K. Learning old tricks from new viruses Nature Medicine. 6: 1091-1092. PMID 11017130 DOI: 10.1038/80409  0.307
2000 Duensing S, Lee LY, Duensing A, Basile J, Piboonniyom S, Gonzalez S, Crum CP, Munger K. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proceedings of the National Academy of Sciences of the United States of America. 97: 10002-7. PMID 10944189 DOI: 10.1073/Pnas.170093297  0.615
2000 Park JS, Boyer S, Mitchell K, Gilfor D, Birrer M, Darlington G, El Deiry W, Firestone GL, Munger K, Band V, Fisher PB, Dent P. Expression of human papilloma virus E7 protein causes apoptosis and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6). The Journal of Biological Chemistry. 275: 18-28. PMID 10617580 DOI: 10.1074/Jbc.275.1.18  0.422
1999 Syken J, De-Medina T, Münger K. TID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functions. Proceedings of the National Academy of Sciences of the United States of America. 96: 8499-504. PMID 10411904 DOI: 10.1073/Pnas.96.15.8499  0.304
1999 Jones DL, Thompson DA, Suh-Bürgmann E, Grace M, Münger K. Expression of the HPV E7 oncoprotein mimics but does not evoke a p53-dependent cellular DNA damage response pathway. Virology. 258: 406-414. PMID 10366578 DOI: 10.1006/Viro.1999.9733  0.496
1998 Timmermann S, Hinds PW, Münger K. Re-expression of endogenous p16(ink4a) in oral squamous cell carcinoma lines by 5-aza-2'-deoxycytidine treatment induces a senescence-like state Oncogene. 17: 3445-3453. PMID 10030668 DOI: 10.1038/Sj.Onc.1202244  0.321
1998 Alani RM, Hasskarl J, Munger K. Alterations in cyclin-dependent kinase 2 function during differentiation of primary human keratinocytes Molecular Carcinogenesis. 23: 226-233. PMID 9869451 DOI: 10.1002/(Sici)1098-2744(199812)23:4<226::Aid-Mc5>3.0.Co;2-N  0.365
1998 Schilling B, De-Medina T, Syken J, Vidal M, Münger K. A novel human DnaJ protein, hTid-1, a homolog of the Drosophila tumor suppressor protein Tid56, can interact with the human papillomavirus type 16 E7 oncoprotein. Virology. 247: 74-85. PMID 9683573 DOI: 10.1006/Viro.1998.9220  0.59
1998 Alani RM, Münger K. Human papillomaviruses and associated malignancies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 16: 330-7. PMID 9440761 DOI: 10.1200/Jco.1998.16.1.330  0.586
1997 Mavromatis KO, Jones DL, Mukherjee R, Yee C, Grace M, Münger K. The carboxyl-terminal zinc-binding domain of the human papillomavirus E7 protein can be functionally replaced by the homologous sequences of the E6 protein. Virus Research. 52: 109-118. PMID 9453149 DOI: 10.1016/S0168-1702(97)00090-7  0.52
1997 Thompson DA, Belinsky G, Chang TH-, Jones DL, Schlegel R, Münger K. The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints. Oncogene. 15: 3025-3035. PMID 9444951 DOI: 10.1038/Sj.Onc.1201495  0.621
1997 Jones DL, Thompson DA, Münger K. Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis Virology. 239: 97-107. PMID 9426450 DOI: 10.1006/Viro.1997.8851  0.522
1996 Jones DL, Münger K. Interactions of the human papillomavirus E7 protein with cell cycle regulators Seminars in Cancer Biology. 7: 327-337. PMID 9284525 DOI: 10.1006/Scbi.1996.0042  0.637
1995 Munger K. The molecular biology of cervical cancer Journal of Cellular Biochemistry. 59: 55-60. PMID 8747378 DOI: 10.1002/Jcb.240590908  0.506
1995 Clemens KE, Brent R, Gyuris J, Munger K. Dimerization of the human papillomavirus E7 oncoprotein in vivo Virology. 214: 289-293. PMID 8525630 DOI: 10.1006/Viro.1995.9926  0.422
1994 Scheffner M, Romanczuk H, Munger K, Huibregtse JM, Mietz JA, Howley PM. Functions of human papillomavirus proteins Current Topics in Microbiology and Immunology. 186: 83-99. PMID 8205847 DOI: 10.1007/978-3-642-78487-3_5  0.575
1994 Brokaw JL, Yee CL, Münger K. A mutational analysis of the amino terminal domain of the human papillomavirus type 16 E7 oncoprotein. Virology. 205: 603-7. PMID 7975265 DOI: 10.1006/Viro.1994.1688  0.573
1994 Arbeit JM, Münger K, Howley PM, Hanahan D. Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice Journal of Virology. 68: 4358-4368. PMID 7515971 DOI: 10.1128/Jvi.68.7.4358-4368.1994  0.526
1993 Wu EW, Clemens KE, Heck DV, Munger K. The human papillomavirus E7 oncoprotein and the cellular transcription factor E2F bind to separate sites on the retinoblastoma tumor suppressor protein Journal of Virology. 67: 2402-2407. PMID 8445736 DOI: 10.1128/Jvi.67.4.2402-2407.1993  0.419
1993 Münger K, Phelps WC. The human papillomavirus E7 protein as a transforming and transactivating factor. Biochimica Et Biophysica Acta. 1155: 111-123. PMID 8389201 DOI: 10.1016/0304-419X(93)90025-8  0.617
1993 Arbeit JM, Munger K, Howley PM, Hanahan D. Neuroepithelial carcinomas in mice transgenic with human papillomavirus type 16 E6/E7 ORFs American Journal of Pathology. 142: 1187-1197. PMID 8386443  0.459
1992 Munger K, Scheffner M, Huibregtse JM, Howley PM. Interactions of HPV E6 and E7 oncoproteins with tumour suppressor gene products Cancer Surveys. 12: 197-217. PMID 1322242  0.543
1992 Scheffner M, Münger K, Huibregtse JM, Howley PM. Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins Embo Journal. 11: 2425-2431. PMID 1321031 DOI: 10.1002/J.1460-2075.1992.Tb05307.X  0.58
1992 Chellappan S, Kraus VB, Kroger B, Munger K, Howley PM, Phelps WC, Nevins JR. Adeno virus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product Proceedings of the National Academy of Sciences of the United States of America. 89: 4549-4553. PMID 1316611 DOI: 10.1073/Pnas.89.10.4549  0.346
1992 Heck DV, Yee CL, Howley PM, Münger K. Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses. Proceedings of the National Academy of Sciences of the United States of America. 89: 4442-6. PMID 1316608 DOI: 10.1073/Pnas.89.10.4442  0.572
1992 Phelps WC, Münger K, Yee CL, Barnes JA, Howley PM. Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein. Journal of Virology. 66: 2418-27. PMID 1312637 DOI: 10.1128/Jvi.66.4.2418-2427.1992  0.433
1991 Phelps WC, Bagchi S, Barnes JA, Raychaudhuri P, Kraus V, Münger K, Howley PM, Nevins JR. Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism. Journal of Virology. 65: 6922-30. PMID 1834862 DOI: 10.1128/Jvi.65.12.6922-6930.1991  0.445
1991 Howley PM, Scheffner M, Huibregtse J, Munger K. Oncoproteins encoded by the cancer-associated human papillomaviruses target the products of the retinoblastoma and p53 tumor suppressor genes Cold Spring Harbor Symposia On Quantitative Biology. 56: 149-155. PMID 1668080 DOI: 10.1101/Sqb.1991.056.01.019  0.345
1991 Scheffner M, Munger K, Byrne JC, Howley PM. The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines Proceedings of the National Academy of Sciences of the United States of America. 88: 5523-5527. PMID 1648218 DOI: 10.1073/Pnas.88.13.5523  0.554
1991 Münger K, Yee CL, Phelps WC, Pietenpol JA, Moses HL, Howley PM. Biochemical and biological differences between E7 oncoproteins of the high- and low-risk human papillomavirus types are determined by amino-terminal sequences. Journal of Virology. 65: 3943-8. PMID 1645802 DOI: 10.1128/Jvi.65.7.3943-3948.1991  0.578
1990 Pietenpol JA, Stein RW, Moran E, Yaciuk P, Schlegel R, Lyons RM, Pittelkow MR, Münger K, Howley PM, Moses HL. TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell. 61: 777-85. PMID 2140528 DOI: 10.1016/0092-8674(90)90188-K  0.383
1989 Phelps WC, Yee CL, Münger K, Howley PM. Functional and sequence similarities between HPV16 E7 and adenovirus E1A. Current Topics in Microbiology and Immunology. 144: 153-66. PMID 2551580 DOI: 10.1007/978-3-642-74578-2_19  0.576
1989 Munger K, Phelps WC, Bubb V, Howley PM. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes Journal of Virology. 63: 4417-4421. PMID 2476573 DOI: 10.1128/Jvi.63.10.4417-4421.1989  0.428
1988 Phelps WC, Yee CL, Münger K, Howley PM. The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell. 53: 539-47. PMID 2836062 DOI: 10.1016/0092-8674(88)90570-3  0.611
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