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Victor C. Yang - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Biomedical Engineering, Biochemistry
Website:
https://pharmacy.umich.edu/people/vcyang

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Xu Y, Zhang X, Wang N, Pei X, Guo Y, Wang J, Barth S, Yu F, Jin Lee S, He H, Yang VC. Cell-Penetrating Peptide Enhanced Insulin Buccal Absorption. International Journal of Pharmaceutics. 119469. PMID 32470482 DOI: 10.1016/J.Ijpharm.2020.119469  0.346
2020 Ji X, Xie S, Jiao Y, Zhang X, Sun D, Yang VC, Wang M, He H, Sun L. MT1-MMP activatable fluorogenic probes with enhanced specificity via high-affinity peptide conjugation for tumor imaging. Biomaterials Science. PMID 32186291 DOI: 10.1039/C9Bm02007A  0.301
2020 Liu Q, Zhang L, Ji X, Shin MC, Xie S, Pan B, Yu F, Zhao J, Yang VC. A self-assembly and stimuli-responsive fusion gelonin delivery system for tumor treatment Journal of Industrial and Engineering Chemistry. 89: 409-415. DOI: 10.1016/J.Jiec.2020.06.012  0.445
2019 Cui H, Zhang B, Ding H, Hu Y, Wang X, Xu L, Jiao X, He H, Wang X, Zeng X, Yang VC. A -Diol/pH Dual-Responsive Upconversion Nanoplatform: Synthesis, Characterization, and Demonstration. Journal of Biomedical Nanotechnology. 15: 487-499. PMID 31165694 DOI: 10.1166/jbn.2019.2700  0.303
2018 Liu E, Zhang M, Cui H, Gong J, Huang Y, Wang J, Cui Y, Dong W, Sun L, He H, Yang VC. Tat-functionalized Ag-FeO nano-composites as tissue-penetrating vehicles for tumor magnetic targeting and drug delivery. Acta Pharmaceutica Sinica. B. 8: 956-968. PMID 30505664 DOI: 10.1016/J.Apsb.2018.07.012  0.449
2018 Ye J, Pei X, Cui H, Yu Z, Lee H, Wang J, Wang X, Sun L, He H, Yang VC. Cellular uptake mechanism and comparative in vitro cytotoxicity studies of monomeric LMWP-siRNA conjugate Journal of Industrial and Engineering Chemistry. 63: 103-111. DOI: 10.1016/J.Jiec.2018.02.005  0.381
2017 Wang H, Moon C, Shin MC, Wang Y, He H, Yang VC, Huang Y. Heparin-Regulated Prodrug-Type Macromolecular Theranostic Systems for Cancer Therapy. Nanotheranostics. 1: 114-130. PMID 29071181 DOI: 10.7150/ntno.18292  0.608
2017 Ye J, Liu E, Gong J, Wang J, Huang Y, He H, Yang VC. High-Yield Synthesis of Monomeric LMWP(CPP)-siRNA Covalent Conjugate for Effective Cytosolic Delivery of siRNA. Theranostics. 7: 2495-2508. PMID 28744330 DOI: 10.7150/thno.19863  0.304
2017 Li R, Pang Z, He H, Lee S, Qin J, Wu J, Pang L, Wang J, Yang VC. Drug depot-anchoring hydrogel: A self-assembling scaffold for localized drug release and enhanced stem cell differentiation. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28694033 DOI: 10.1016/J.Jconrel.2017.07.008  0.354
2017 Shin MC, Min KA, Cheong H, Moon C, Huang Y, He H, Yang VC. Tandem-Multimeric F3-Gelonin Fusion Toxins for Enhanced Anti-Cancer Activity for Prostate Cancer Treatment. International Journal of Pharmaceutics. PMID 28359823 DOI: 10.1016/J.Ijpharm.2017.03.072  0.597
2017 Huang Y, Yang VC, Li F, Shin MC, Wang H, Min KA, Zhang M, Chen Y. Improved Protein Toxin Delivery Based on ATTEMPTS Systems. Current Drug Targets. PMID 28260497 DOI: 10.2174/1389450118666170302094758  0.418
2017 Gao W, Ye G, Duan X, Yang X, Yang VC. Transferrin receptor-targeted pH-sensitive micellar system for diminution of drug resistance and targetable delivery in multidrug-resistant breast cancer. International Journal of Nanomedicine. 12: 1047-1064. PMID 28223798 DOI: 10.2147/Ijn.S115215  0.391
2017 Lee K, David AE, Zhang J, Shin MC, Yang VC. Enhanced accumulation of theranostic nanoparticles in brain tumor by external magnetic field mediated in situ clustering of magnetic nanoparticles Journal of Industrial and Engineering Chemistry. 54: 389-397. DOI: 10.1016/J.Jiec.2017.06.019  0.421
2017 Zhang P, Ye J, Liu E, Sun L, Zhang J, Lee S, Gong J, He H, Yang VC. Aptamer-coded DNA nanoparticles for targeted doxorubicin delivery using pH-sensitive spacer Frontiers of Chemical Science and Engineering. 11: 529-536. DOI: 10.1007/S11705-017-1645-Z  0.385
2016 Lin T, Zhao P, Jiang Y, Tang Y, Jin H, Pan Z, He H, Yang VC, Huang Y. Blood-Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy. Acs Nano. 10: 9999-10012. PMID 27934069 DOI: 10.1021/Acsnano.6B04268  0.448
2016 Ye J, Liu E, Yu Z, Pei X, Chen S, Zhang P, Shin MC, Gong J, He H, Yang VC. CPP-Assisted Intracellular Drug Delivery, What Is Next? International Journal of Molecular Sciences. 17. PMID 27854260 DOI: 10.3390/Ijms17111892  0.442
2016 Lin T, Liu E, He H, Shin MC, Moon C, Yang VC, Huang Y. Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides. Acta Pharmaceutica Sinica. B. 6: 352-8. PMID 27471676 DOI: 10.1016/J.Apsb.2016.04.001  0.589
2016 Shin MC, Min KA, Cheong H, Moon C, Huang Y, He H, Yang VC. Preparation and Characterization of Gelonin-Melittin Fusion Biotoxin for Synergistically Enhanced Anti-Tumor Activity. Pharmaceutical Research. PMID 27251414 DOI: 10.1007/S11095-016-1959-4  0.592
2016 Sheng J, He H, Han L, Qin J, Chen S, Ru G, Li R, Yang P, Wang J, Yang VC. Enhancing insulin oral absorption by using mucoadhesive nanoparticles loaded with LMWP-linked insulin conjugates. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27178809 DOI: 10.1016/J.Jconrel.2016.05.015  0.336
2016 Chen S, Liang Q, Xie S, Liu E, Yu Z, Sun L, Shin MC, Lee SJ, He H, Yang VC. Curcumin based combination therapy for anti-breast cancer: from in vitro drug screening to in vivo efficacy evaluation Frontiers of Chemical Science and Engineering. 10: 383-388. DOI: 10.1007/S11705-016-1574-2  0.381
2015 He H, Sun L, Ye J, Liu E, Chen S, Liang Q, Shin MC, Yang VC. Enzyme-triggered, cell penetrating peptide-mediated delivery of anti-tumor agents. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26514292 DOI: 10.1016/J.Jconrel.2015.10.040  0.445
2015 Wang Y, Lin T, Zhang W, Jiang Y, Jin H, He H, Yang VC, Chen Y, Huang Y. A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging. Theranostics. 5: 787-95. PMID 26000052 DOI: 10.7150/Thno.11139  0.346
2015 Shin MC, Zhang J, Min KA, He H, David AE, Huang Y, Yang VC. PTD-Modified ATTEMPTS for Enhanced Toxin-based Cancer Therapy: An In Vivo Proof-of-Concept Study. Pharmaceutical Research. 32: 2690-703. PMID 25701313 DOI: 10.1007/S11095-015-1653-Y  0.305
2015 Ye J, Shin MC, Liang Q, He H, Yang VC. 15 years of ATTEMPTS: a macromolecular drug delivery system based on the CPP-mediated intracellular drug delivery and antibody targeting. Journal of Controlled Release : Official Journal of the Controlled Release Society. 205: 58-69. PMID 25483423 DOI: 10.1016/J.Jconrel.2014.12.002  0.441
2015 Shin MC, Zhao J, Zhang J, Huang Y, He H, Wang M, Min KA, Yang VC. Recombinant TAT-gelonin fusion toxin: synthesis and characterization of heparin/protamine-regulated cell transduction. Journal of Biomedical Materials Research. Part A. 103: 409-19. PMID 24733757 DOI: 10.1002/Jbm.A.35188  0.417
2014 Liu E, Sheng J, Ye J, Wang Y, Gong J, Yang VC, Wang J, He H. CPP mediated insulin delivery: current status and promising future. Current Pharmaceutical Biotechnology. 15: 240-55. PMID 25312540 DOI: 10.2174/1389201015666140813125840  0.316
2014 Shin MC, Zhang J, Min KA, Lee K, Moon C, Balthasar JP, Yang VC. Combination of antibody targeting and PTD-mediated intracellular toxin delivery for colorectal cancer therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 194: 197-210. PMID 25204286 DOI: 10.1016/J.Jconrel.2014.08.030  0.596
2014 Wang H, Zhao Y, Wang H, Gong J, He H, Shin MC, Yang VC, Huang Y. Low-molecular-weight protamine-modified PLGA nanoparticles for overcoming drug-resistant breast cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. 192: 47-56. PMID 25003794 DOI: 10.1016/J.Jconrel.2014.06.051  0.406
2014 He H, Ye J, Liu E, Liang Q, Liu Q, Yang VC. Low molecular weight protamine (LMWP): a nontoxic protamine substitute and an effective cell-penetrating peptide. Journal of Controlled Release : Official Journal of the Controlled Release Society. 193: 63-73. PMID 24943246 DOI: 10.1016/J.Jconrel.2014.05.056  0.36
2014 He H, Ye J, Wang Y, Liu Q, Chung HS, Kwon YM, Shin MC, Lee K, Yang VC. Cell-penetrating peptides meditated encapsulation of protein therapeutics into intact red blood cells and its application. Journal of Controlled Release : Official Journal of the Controlled Release Society. 176: 123-32. PMID 24374002 DOI: 10.1016/J.Jconrel.2013.12.019  0.396
2014 Zhang J, Shin MC, Yang VC. Magnetic targeting of novel heparinized iron oxide nanoparticles evaluated in a 9L-glioma mouse model. Pharmaceutical Research. 31: 579-92. PMID 24065589 DOI: 10.1007/S11095-013-1182-5  0.364
2014 Absar S, Nahar K, Choi S, Ahsan F, Yang VC, Kwon YM. Serum albumin-protamine conjugate for biocompatible platform for targeted delivery of therapeutic macromolecules. Journal of Biomedical Materials Research. Part A. 102: 2481-90. PMID 23946132 DOI: 10.1002/Jbm.A.34916  0.436
2014 Shin MC, Zhang J, Min KA, Lee K, Byun Y, David AE, He H, Yang VC. Cell-penetrating peptides: achievements and challenges in application for cancer treatment. Journal of Biomedical Materials Research. Part A. 102: 575-87. PMID 23852939 DOI: 10.1002/Jbm.A.34859  0.441
2014 Ren X, Chen H, Yang V, Sun D. Iron oxide nanoparticle-based theranostics for cancer imaging and therapy Frontiers of Chemical Science and Engineering. 8: 253-264. DOI: 10.1007/S11705-014-1425-Y  0.321
2014 Wang Y, Jiang Y, Zhang M, Tan J, Liang J, Wang H, Li Y, He H, Yang VC, Huang Y. Protease-Activatable Hybrid Nanoprobe for Tumor Imaging Advanced Functional Materials. 24: 5443-5453. DOI: 10.1002/Adfm.201400419  0.361
2013 Zhang J, Shin MC, David AE, Zhou J, Lee K, He H, Yang VC. Long-circulating heparin-functionalized magnetic nanoparticles for potential application as a protein drug delivery platform. Molecular Pharmaceutics. 10: 3892-902. PMID 24024964 DOI: 10.1021/Mp400360Q  0.417
2013 Zhou J, Zhang J, David AE, Yang VC. Magnetic tumor targeting of β-glucosidase immobilized iron oxide nanoparticles. Nanotechnology. 24: 375102. PMID 23974977 DOI: 10.1088/0957-4484/24/37/375102  0.355
2013 Shin MC, Zhang J, David AE, Trommer WE, Kwon YM, Min KA, Kim JH, Yang VC. Chemically and biologically synthesized CPP-modified gelonin for enhanced anti-tumor activity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 169-78. PMID 23973813 DOI: 10.1016/J.Jconrel.2013.08.016  0.409
2013 Min KA, Shin MC, Yu F, Yang M, David AE, Yang VC, Rosania GR. Pulsed magnetic field improves the transport of iron oxide nanoparticles through cell barriers Acs Nano. 7: 2161-2171. PMID 23373613 DOI: 10.1021/Nn3057565  0.329
2013 Huang Y, Jiang Y, Wang H, Wang J, Shin MC, Byun Y, He H, Liang Y, Yang VC. Curb challenges of the "Trojan Horse" approach: smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery. Advanced Drug Delivery Reviews. 65: 1299-315. PMID 23369828 DOI: 10.1016/J.Addr.2012.11.007  0.422
2013 He H, David A, Chertok B, Cole A, Lee K, Zhang J, Wang J, Huang Y, Yang VC. Magnetic nanoparticles for tumor imaging and therapy: a so-called theranostic system. Pharmaceutical Research. 30: 2445-58. PMID 23344909 DOI: 10.1007/S11095-013-0982-Y  0.776
2013 Absar S, Choi S, Ahsan F, Cobos E, Yang VC, Kwon YM. Preparation and characterization of anionic oligopeptide-modified tissue plasminogen activator for triggered delivery: an approach for localized thrombolysis. Thrombosis Research. 131: e91-9. PMID 23269380 DOI: 10.1016/J.Thromres.2012.11.030  0.353
2013 Park YS, David AE, Park KM, Lin CY, Than KD, Lee K, Park JB, Jo I, Park KD, Yang VC. Controlled release of simvastatin from in situ forming hydrogel triggers bone formation in MC3T3-E1 cells. The Aaps Journal. 15: 367-76. PMID 23250670 DOI: 10.1208/S12248-012-9442-6  0.325
2013 Sun Y, Dong W, Wang H, Huang Y, Gu H, Yang VC, Gong J. Template synthesis of PMAA@chitosan hollow nanorods for docetaxel delivery Polymer Chemistry. 4: 2489-2495. DOI: 10.1039/C3Py21157F  0.421
2013 He H, Liang Q, Shin MC, Lee K, Gong J, Ye J, Liu Q, Wang J, Yang V. Significance and strategies in developing delivery systems for bio-macromolecular drugs Frontiers of Chemical Science and Engineering. 7: 496-507. DOI: 10.1007/S11705-013-1362-1  0.348
2013 Ye J, He H, Gong J, Dong W, Huang Y, Wang J, Chen G, Yang VC. Ultrasound-mediated targeted microbubbles: a new vehicle for cancer therapy Frontiers of Chemical Science and Engineering. 7: 20-28. DOI: 10.1007/S11705-013-1311-Z  0.394
2013 He H, Ye J, Sheng J, Wang J, Huang Y, Chen G, Wang J, Yang VC. Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous composites Frontiers of Chemical Science and Engineering. 7: 9-19. DOI: 10.1007/S11705-013-1306-9  0.323
2012 Adulnirath A, Chung SW, Park J, Hwang SR, Kim JY, Yang VC, Kim SY, Moon HT, Byun Y. Cyclic RGDyk-conjugated LMWH-taurocholate derivative as a targeting angiogenesis inhibitor. Journal of Controlled Release : Official Journal of the Controlled Release Society. 164: 8-16. PMID 23063549 DOI: 10.1016/J.Jconrel.2012.10.001  0.351
2012 Hwang SR, Seo DH, Al-Hilal TA, Jeon OC, Kang JH, Kim SH, Kim HS, Chang YT, Kang YM, Yang VC, Byun Y. Orally active desulfated low molecular weight heparin and deoxycholic acid conjugate, 6ODS-LHbD, suppresses neovascularization and bone destruction in arthritis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 163: 374-84. PMID 23041275 DOI: 10.1016/J.Jconrel.2012.09.013  0.311
2012 Wang J, Huang Y, David AE, Chertok B, Zhang L, Yu F, Yang VC. Magnetic nanoparticles for MRI of brain tumors. Current Pharmaceutical Biotechnology. 13: 2403-16. PMID 23016645 DOI: 10.2174/138920112803341824  0.694
2012 Zhang J, Deng D, Zhu H, Byun Y, Yang VC, Gu Y. Folate-conjugated thermo-responsive micelles for tumor targeting. Journal of Biomedical Materials Research. Part A. 100: 3134-42. PMID 22826176 DOI: 10.1002/Jbm.A.34230  0.394
2012 Shen M, Huang Y, Han L, Qin J, Fang X, Wang J, Yang VC. Multifunctional drug delivery system for targeting tumor and its acidic microenvironment. Journal of Controlled Release : Official Journal of the Controlled Release Society. 161: 884-92. PMID 22587941 DOI: 10.1016/J.Jconrel.2012.05.013  0.442
2012 Kim JY, Shim G, Choi HW, Park J, Chung SW, Kim S, Kim K, Kwon IC, Kim CW, Kim SY, Yang VC, Oh YK, Byun Y. Tumor vasculature targeting following co-delivery of heparin-taurocholate conjugate and suberoylanilide hydroxamic acid using cationic nanolipoplex. Biomaterials. 33: 4424-30. PMID 22425551 DOI: 10.1016/J.Biomaterials.2012.02.066  0.412
2012 Lee TY, Park YS, Garcia GA, Sunahara RK, Woods JH, Yang VC. Cell permeable cocaine esterases constructed by chemical conjugation and genetic recombination. Molecular Pharmaceutics. 9: 1361-73. PMID 22404344 DOI: 10.1021/Mp200623W  0.556
2012 David AE, Gong J, Chertok B, Domszy RC, Moon C, Park YS, Wang NS, Yang AJ, Yang VC. Immobilized thermolysin for highly efficient production of low-molecular-weight protamine--an attractive cell-penetrating peptide for macromolecular drug delivery applications. Journal of Biomedical Materials Research. Part A. 100: 211-9. PMID 22042599 DOI: 10.1002/Jbm.A.33244  0.749
2012 Absar S, Choi S, Yang VC, Kwon YM. Heparin-triggered release of camouflaged tissue plasminogen activator for targeted thrombolysis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 46-54. PMID 21930168 DOI: 10.1016/J.Jconrel.2011.09.060  0.359
2011 David AE, Cole AJ, Yang VC. Magnetically targeted nanoparticles for brain tumor therapy: what does the future hold? Nanomedicine (London, England). 6: 1133-5. PMID 21929450 DOI: 10.2217/Nnm.11.99  0.572
2011 Chertok B, David AE, Yang VC. Brain tumor targeting of magnetic nanoparticles for potential drug delivery: effect of administration route and magnetic field topography. Journal of Controlled Release : Official Journal of the Controlled Release Society. 155: 393-9. PMID 21763736 DOI: 10.1016/J.Jconrel.2011.06.033  0.704
2011 Cole AJ, David AE, Wang J, Galbán CJ, Yang VC. Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles. Biomaterials. 32: 6291-301. PMID 21684593 DOI: 10.1016/J.Biomaterials.2011.05.024  0.615
2011 Chertok B, David AE, Yang VC. Magnetically-enabled and MR-monitored selective brain tumor protein delivery in rats via magnetic nanocarriers. Biomaterials. 32: 6245-53. PMID 21632104 DOI: 10.1016/J.Biomaterials.2011.05.004  0.716
2011 Cole AJ, Yang VC, David AE. Cancer theranostics: the rise of targeted magnetic nanoparticles. Trends in Biotechnology. 29: 323-32. PMID 21489647 DOI: 10.1016/J.Tibtech.2011.03.001  0.58
2011 Li J, Feng L, Fan L, Zha Y, Guo L, Zhang Q, Chen J, Pang Z, Wang Y, Jiang X, Yang VC, Wen L. Targeting the brain with PEG-PLGA nanoparticles modified with phage-displayed peptides. Biomaterials. 32: 4943-50. PMID 21470674 DOI: 10.1016/J.Biomaterials.2011.03.031  0.404
2011 Choi YS, Lee JY, Suh JS, Lee SJ, Yang VC, Chung CP, Park YJ. Cell penetrating peptides for tumor targeting. Current Pharmaceutical Biotechnology. 12: 1166-82. PMID 21470141 DOI: 10.2174/138920111796117391  0.424
2011 David AE, Cole AJ, Chertok B, Park YS, Yang VC. A combined theoretical and in vitro modeling approach for predicting the magnetic capture and retention of magnetic nanoparticles in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. 152: 67-75. PMID 21295085 DOI: 10.1016/J.Jconrel.2011.01.033  0.73
2011 Huang Y, Rao Y, Chen J, Yang VC, Liang W. Polysorbate cationic synthetic vesicle for gene delivery. Journal of Biomedical Materials Research. Part A. 96: 513-9. PMID 21254382 DOI: 10.1002/Jbm.A.32999  0.312
2011 Cole AJ, David AE, Wang J, Galbán CJ, Hill HL, Yang VC. Polyethylene glycol modified, cross-linked starch-coated iron oxide nanoparticles for enhanced magnetic tumor targeting. Biomaterials. 32: 2183-93. PMID 21176955 DOI: 10.1016/J.Biomaterials.2010.11.040  0.572
2011 Lee JY, Choi YS, Suh JS, Kwon YM, Yang VC, Lee SJ, Chung CP, Park YJ. Cell-penetrating chitosan/doxorubicin/TAT conjugates for efficient cancer therapy. International Journal of Cancer. 128: 2470-80. PMID 20669230 DOI: 10.1002/Ijc.25578  0.402
2010 Min KA, Yu F, Yang VC, Zhang X, Rosania GR. Transcellular Transport of Heparin-coated Magnetic Iron Oxide Nanoparticles (Hep-MION) Under the Influence of an Applied Magnetic Field. Pharmaceutics. 2: 119-135. PMID 21152371 DOI: 10.3390/Pharmaceutics2020119  0.354
2010 Park JW, Jeon OC, Kim SK, Al-Hilal TA, Jin SJ, Moon HT, Yang VC, Kim SY, Byun Y. High antiangiogenic and low anticoagulant efficacy of orally active low molecular weight heparin derivatives. Journal of Controlled Release : Official Journal of the Controlled Release Society. 148: 317-26. PMID 20869408 DOI: 10.1016/J.Jconrel.2010.09.014  0.396
2010 Huang Y, Yu F, Park YS, Wang J, Shin MC, Chung HS, Yang VC. Co-administration of protein drugs with gold nanoparticles to enable percutaneous delivery. Biomaterials. 31: 9086-91. PMID 20828812 DOI: 10.1016/J.Biomaterials.2010.08.046  0.336
2010 Huang Y, Park YS, Wang J, Moon C, Kwon YM, Chung HS, Park YJ, Yang VC. ATTEMPTS system: a macromolecular prodrug strategy for cancer drug delivery. Current Pharmaceutical Design. 16: 2369-76. PMID 20618157 DOI: 10.2174/138161210791920441  0.658
2010 Chertok B, David AE, Yang VC. Polyethyleneimine-modified iron oxide nanoparticles for brain tumor drug delivery using magnetic targeting and intra-carotid administration. Biomaterials. 31: 6317-24. PMID 20494439 DOI: 10.1016/J.Biomaterials.2010.04.043  0.722
2010 Yu F, Zhang L, Huang Y, Sun K, David AE, Yang VC. The magnetophoretic mobility and superparamagnetism of core-shell iron oxide nanoparticles with dual targeting and imaging functionality. Biomaterials. 31: 5842-8. PMID 20434209 DOI: 10.1016/J.Biomaterials.2010.03.072  0.394
2010 Huang Y, Park YS, Moon C, David AE, Chung HS, Yang VC. Synthetic skin-permeable proteins enabling needleless immunization. Angewandte Chemie (International Ed. in English). 49: 2724-7. PMID 20232417 DOI: 10.1002/Anie.200906153  0.596
2010 Park YS, Huang Y, Park YJ, David AE, White L, He H, Chung HS, Yang VC. Specific down regulation of 3T3-L1 adipocyte differentiation by cell-permeable antisense HIF1alpha-oligonucleotide. Journal of Controlled Release : Official Journal of the Controlled Release Society. 144: 82-90. PMID 20109509 DOI: 10.1016/J.Jconrel.2010.01.026  0.311
2010 Chertok B, Cole AJ, David AE, Yang VC. Comparison of electron spin resonance spectroscopy and inductively-coupled plasma optical emission spectroscopy for biodistribution analysis of iron-oxide nanoparticles. Molecular Pharmaceutics. 7: 375-85. PMID 20039679 DOI: 10.1021/Mp900161H  0.734
2010 Choi YS, Lee JY, Suh JS, Kwon YM, Lee SJ, Chung JK, Lee DS, Yang VC, Chung CP, Park YJ. The systemic delivery of siRNAs by a cell penetrating peptide, low molecular weight protamine. Biomaterials. 31: 1429-43. PMID 19954842 DOI: 10.1016/J.Biomaterials.2009.11.001  0.385
2010 Park JB, Kwon YM, Lee TY, Brim R, Ko MC, Sunahara RK, Woods JH, Yang VC. PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 142: 174-9. PMID 19857534 DOI: 10.1016/J.Jconrel.2009.10.015  0.544
2010 Urva SR, Yang VC, Balthasar JP. Physiologically based pharmacokinetic model for T84.66: a monoclonal anti-CEA antibody. Journal of Pharmaceutical Sciences. 99: 1582-600. PMID 19774657 DOI: 10.1002/Jps.21918  0.322
2010 Yu F, Yang VC. Size-tunable synthesis of stable superparamagnetic iron oxide nanoparticles for potential biomedical applications. Journal of Biomedical Materials Research. Part A. 92: 1468-75. PMID 19402138 DOI: 10.1002/Jbm.A.32489  0.307
2010 He H, Dong W, Gong J, Wang J, Yang VC. Developing macromolecular therapeutics: The future drug-of-choice Frontiers of Chemical Engineering in China. 4: 10-17. DOI: 10.1007/S11705-009-0291-5  0.364
2009 Chen JS, Chan DC, Chung MJ, Chang LC, Yang VC. Altered fibrinolytic activities in gastric cancer and uremic patients after intervention. Clinical Nephrology. 72: 468-72. PMID 19954724  0.444
2009 Zhang H, Wang L, Park JB, Park P, Yang VC, Hollister SJ, La Marca F, Lin CY. Intradiscal injection of simvastatin retards progression of intervertebral disc degeneration induced by stab injury. Arthritis Research & Therapy. 11: R172. PMID 19912653 DOI: 10.1186/Ar2861  0.312
2009 Zhang L, Yu F, Cole AJ, Chertok B, David AE, Wang J, Yang VC. Gum arabic-coated magnetic nanoparticles for potential application in simultaneous magnetic targeting and tumor imaging. The Aaps Journal. 11: 693-9. PMID 19842043 DOI: 10.1208/S12248-009-9151-Y  0.746
2009 Chertok B, David AE, Moffat BA, Yang VC. Substantiating in vivo magnetic brain tumor targeting of cationic iron oxide nanocarriers via adsorptive surface masking. Biomaterials. 30: 6780-7. PMID 19782394 DOI: 10.1016/J.Biomaterials.2009.08.040  0.721
2009 Kwon YM, Chung HS, Moon C, Yockman J, Park YJ, Gitlin SD, David AE, Yang VC. L-Asparaginase encapsulated intact erythrocytes for treatment of acute lymphoblastic leukemia (ALL). Journal of Controlled Release : Official Journal of the Controlled Release Society. 139: 182-9. PMID 19577600 DOI: 10.1016/J.Jconrel.2009.06.027  0.592
2009 Yu F, Huang Y, Cole AJ, Yang VC. The artificial peroxidase activity of magnetic iron oxide nanoparticles and its application to glucose detection. Biomaterials. 30: 4716-22. PMID 19515418 DOI: 10.1016/J.Biomaterials.2009.05.005  0.548
2009 Li YT, Kwon YM, Spangrude GJ, Liang JF, Chung HS, Park YJ, Yang VC. Preliminary in vivo evaluation of the protein transduction domain-modified ATTEMPTS approach in enhancing asparaginase therapy. Journal of Biomedical Materials Research. Part A. 91: 209-20. PMID 18814276 DOI: 10.1002/Jbm.A.32204  0.542
2008 Suh JS, Lee JY, Choi YS, Yu F, Yang V, Lee SJ, Chung CP, Park YJ. Efficient labeling of mesenchymal stem cells using cell permeable magnetic nanoparticles. Biochemical and Biophysical Research Communications. 379: 669-75. PMID 19101509 DOI: 10.1016/J.Bbrc.2008.12.041  0.353
2008 Kwon YM, Li Y, Naik S, Liang JF, Huang Y, Park YJ, Yang VC. The ATTEMPTS delivery systems for macromolecular drugs. Expert Opinion On Drug Delivery. 5: 1255-66. PMID 18976135 DOI: 10.1517/17425240802498059  0.693
2008 Kwon YM, Li YT, Liang JF, Park YJ, Chang LC, Yang VC. PTD-modified ATTEMPTS system for enhanced asparaginase therapy: a proof-of-concept investigation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 130: 252-8. PMID 18652856 DOI: 10.1016/J.Jconrel.2008.06.017  0.692
2008 Chertok B, Moffat BA, David AE, Yu F, Bergemann C, Ross BD, Yang VC. Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors. Biomaterials. 29: 487-96. PMID 17964647 DOI: 10.1016/J.Biomaterials.2007.08.050  0.708
2008 Moon C, Kwon YM, Lee WK, Park YJ, Chang LC, Yang VC. A novel polyrotaxane-based intracellular delivery system for camptothecin: in vitro feasibility evaluation. Journal of Biomedical Materials Research. Part A. 84: 238-46. PMID 17607767 DOI: 10.1002/Jbm.A.31452  0.72
2008 Chertok B, David A, Yang V. Delivery of functional proteins to brain tumor using MRI-monitored, magnetically-targeted nanoparticles Journal of Controlled Release. 132: e61-e62. DOI: 10.1016/J.Jconrel.2008.09.058  0.708
2008 Chertok B, David AE, Yang VC. Glioma-targeted platform for potential intracellular drug delivery: Design and evaluation 8th World Biomaterials Congress 2008. 2: 951.  0.654
2008 Chertok B, David AE, Yang VC. Strategies for enhanced brain tumor accumulation of magnetic nanoparticles for potential drug delivery Technical Proceedings of the 2008 Nsti Nanotechnology Conference and Trade Show, Nsti-Nanotech, Nanotechnology 2008. 2: 8-11.  0.682
2007 Moon C, Kwon YM, Lee WK, Park YJ, Yang VC. In vitro assessment of a novel polyrotaxane-based drug delivery system integrated with a cell-penetrating peptide. Journal of Controlled Release : Official Journal of the Controlled Release Society. 124: 43-50. PMID 17904680 DOI: 10.1016/J.Jconrel.2007.08.029  0.642
2007 Chertok B, David AE, Huang Y, Yang VC. Glioma selectivity of magnetically targeted nanoparticles: a role of abnormal tumor hydrodynamics. Journal of Controlled Release : Official Journal of the Controlled Release Society. 122: 315-23. PMID 17628157 DOI: 10.1016/J.Jconrel.2007.05.030  0.702
2005 Yang VC, Naik SS, Song H, Dombkowski AA, Crippen G, Liang JF. Construction and characterization of a t-PA mutant for use in ATTEMPTS: a drug delivery system for achieving targeted thrombolysis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 110: 164-76. PMID 16260060 DOI: 10.1016/J.Jconrel.2005.09.027  0.575
2005 Wang T, Yang Z, Emregul E, David A, Balthasar JP, Liang J, Yang VC. Strategies for improving the functionality of an affinity bioreactor. International Journal of Pharmaceutics. 306: 132-41. PMID 16246511 DOI: 10.1016/J.Ijpharm.2005.09.011  0.612
2005 Liang JF, Yang VC. Synthesis of doxorubicin-peptide conjugate with multidrug resistant tumor cell killing activity. Bioorganic & Medicinal Chemistry Letters. 15: 5071-5. PMID 16168650 DOI: 10.1016/J.Bmcl.2005.07.087  0.363
2005 Park YJ, Chang LC, Liang JF, Moon C, Chung CP, Yang VC. Nontoxic membrane translocation peptide from protamine, low molecular weight protamine (LMWP), for enhanced intracellular protein delivery: in vitro and in vivo study. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1555-7. PMID 16033808 DOI: 10.1096/Fj.04-2322Fje  0.715
2005 Chang LC, Lee HF, Chung MJ, Yang VC. PEG-modified protamine with improved pharmacological/pharmaceutical properties as a potential protamine substitute: synthesis and in vitro evaluation. Bioconjugate Chemistry. 16: 147-55. PMID 15656586 DOI: 10.1021/Bc0499735  0.554
2005 Naik SS, Liang JF, Park YJ, Lee WK, Yang VC. Application of "ATTEMPTS" for drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 101: 35-45. PMID 15588892 DOI: 10.1016/J.Jconrel.2004.07.020  0.61
2004 Chen PC, Kohane DS, Park YJ, Bartlett RH, Langer R, Yang VC. Injectable microparticle-gel system for prolonged and localized lidocaine release. II. In vivo anesthetic effects. Journal of Biomedical Materials Research. Part A. 70: 459-66. PMID 15293320 DOI: 10.1002/Jbm.A.30101  0.682
2004 Chen PC, Park YJ, Chang LC, Kohane DS, Bartlett RH, Langer R, Yang VC. Injectable microparticle-gel system for prolonged and localized lidocaine release. I. In vitro characterization. Journal of Biomedical Materials Research. Part A. 70: 412-9. PMID 15293314 DOI: 10.1002/Jbm.A.30086  0.739
2003 Park YJ, Liang JF, Ko KS, Kim SW, Yang VC. Low molecular weight protamine as an efficient and nontoxic gene carrier: in vitro study. The Journal of Gene Medicine. 5: 700-11. PMID 12898639 DOI: 10.1002/Jgm.402  0.315
2003 Liang JF, Zhen L, Chang LC, Yang VC. A less toxic heparin antagonist--low molecular weight protamine. Biochemistry. Biokhimii︠a︡. 68: 116-20. PMID 12693985 DOI: 10.1023/A:1022109905487  0.524
2003 Park YJ, Liang JF, Song H, Li YT, Naik S, Yang VC. ATTEMPTS: a heparin/protamine-based triggered release system for the delivery of enzyme drugs without associated side-effects. Advanced Drug Delivery Reviews. 55: 251-65. PMID 12564979 DOI: 10.1016/S0169-409X(02)00181-3  0.675
2002 Yang Z, Zhang Y, Markland P, Yang VC. Poly(glutamic acid) poly(ethylene glycol) hydrogels prepared by photoinduced polymerization: Synthesis, characterization, and preliminary release studies of protein drugs. Journal of Biomedical Materials Research. 62: 14-21. PMID 12124782 DOI: 10.1002/Jbm.10219  0.355
2002 Liang JF, Li YT, Song H, Park YJ, Naik SS, Yang VC. ATTEMPTS: a heparin/protamine-based delivery system for enzyme drugs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 78: 67-79. PMID 11772450 DOI: 10.1016/S0168-3659(01)00484-9  0.644
2001 Lee LM, Chang LC, Wrobleski S, Wakefield TW, Yang VC. Low molecular weight protamine as nontoxic heparin/low molecular weight heparin antidote (III): preliminary in vivo evaluation of efficacy and toxicity using a canine model. Aaps Pharmsci. 3: E19. PMID 11741270 DOI: 10.1208/Ps030319  0.678
2001 Chang LC, Liang JF, Lee HF, Lee LM, Yang VC. Low molecular weight protamine (LMWP) as nontoxic heparin/low molecular weight heparin antidote (II): in vitro evaluation of efficacy and toxicity. Aaps Pharmsci. 3: E18. PMID 11741269 DOI: 10.1208/Ps030318  0.664
2001 Chang LC, Lee HF, Yang Z, Yang VC. Low molecular weight protamine (LMWP) as nontoxic heparin/low molecular weight heparin antidote (I): preparation and characterization. Aaps Pharmsci. 3: E17. PMID 11741268 DOI: 10.1208/Ps030317  0.561
2001 Park YJ, Liang J, Yang Z, Yang VC. Controlled release of clot-dissolving tissue-type plasminogen activator from a poly(L-glutamic acid) semi-interpenetrating polymer network hydrogel Journal of Controlled Release. 75: 37-44. PMID 11451495 DOI: 10.1016/S0168-3659(01)00360-1  0.315
2001 Liang JF, Park YJ, Song H, Li YT, Yang VC. ATTEMPTS: a heparin/protamine-based prodrug approach for delivery of thrombolytic drugs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 72: 145-56. PMID 11389993 DOI: 10.1016/S0168-3659(01)00270-X  0.483
2000 Liang JF, Li YT, Connell ME, Yang VC. Synthesis and characterization of positively charged tPA as a prodrug using heparin/protamine-based drug delivery system. Aaps Pharmsci. 2: E7. PMID 11741223 DOI: 10.1208/ps020107  0.464
2000 Song H, Liang JF, Yang VC. A prodrug approach for delivery of t-PA: Construction of the cationic t-PA prodrug by a recombinant method and preliminary in vitro evaluation of the construct Asaio Journal. 46: 663-668. PMID 11110262 DOI: 10.1097/00002480-200011000-00005  0.359
2000 Byun Y, Chang LC, Lee LM, Han IS, Singh VK, Yang VC. Low molecular weight protamine: a potent but nontoxic antagonist to heparin/low molecular weight protamine. Asaio Journal (American Society For Artificial Internal Organs : 1992). 46: 435-9. PMID 10926141 DOI: 10.1097/00002480-200007000-00013  0.663
2000 Liang JF, Li YT, Yang VC. A novel approach for delivery of enzyme drugs: preliminary demonstration of feasibility and utility in vitro. International Journal of Pharmaceutics. 202: 11-20. PMID 10915922 DOI: 10.1016/S0378-5173(00)00414-2  0.475
2000 Liang JF, Li YT, Yang VC. Biomedical application of immobilized enzymes. Journal of Pharmaceutical Sciences. 89: 979-90. PMID 10906721 DOI: 10.1002/1520-6017(200008)89:8<979::AID-JPS2>3.0.CO;2-H  0.364
2000 Liang JF, Song H, Li YT, Yang VC. A novel heparin/protamine-based pro-drug type delivery system for protease drugs. Journal of Pharmaceutical Sciences. 89: 664-73. PMID 10756332 DOI: 10.1002/(SICI)1520-6017(200005)89:5<664::AID-JPS12>3.0.CO;2-9  0.495
2000 Liang JF, Li Y, Yang VC. The potential mechanism for the effect of heparin on tissue plasminogen activator-mediated plasminogen activation. Thrombosis Research. 97: 349-58. PMID 10709911 DOI: 10.1016/S0049-3848(99)00188-7  0.455
1999 Chang LC, Meyerhoff ME, Yang VC. Electrochemical assay of plasminogen activators in plasma using polyion-sensitive membrane electrode detection. Analytical Biochemistry. 276: 8-12. PMID 10585738 DOI: 10.1006/Abio.1999.4299  0.488
1999 Markland P, Zhang Y, Amidon GL, Yang VC. A pH- and ionic strength-responsive polypeptide hydrogel: Synthesis, characterization, and preliminary protein release studies Journal of Biomedical Materials Research. 47: 595-602. PMID 10497296 DOI: 10.1002/(Sici)1097-4636(19991215)47:4<595::Aid-Jbm17>3.0.Co;2-I  0.304
1999 Yun JH, Han IS, Chang LC, Ramamurthy N, Meyerhoff ME, Yang VC. Electrochemical sensors for polyionic macromolecules: development and applications in pharmaceutical research. Pharmaceutical Science & Technology Today. 2: 102-110. PMID 10322363 DOI: 10.1016/S1461-5347(99)00121-2  0.478
1999 Byun Y, Singh VK, Yang VC. Low molecular weight protamine: A potential nontoxic heparin antagonist Thrombosis Research. 94: 53-61. PMID 10213181 DOI: 10.1016/S0049-3848(98)00201-1  0.357
1999 Wang H, Song H, Yang VC. A recombinant prodrug type approach for triggered delivery of streptokinase Journal of Controlled Release. 59: 119-122. PMID 10210728 DOI: 10.1016/S0168-3659(99)00019-X  0.341
1999 Markland P, Amidon GL, Yang VC. Modified polypeptides containing γ-benzyl glutamic acid as drug delivery platforms International Journal of Pharmaceutics. 178: 183-192. PMID 10205638 DOI: 10.1016/S0378-5173(98)00373-1  0.328
1999 Yang VC, Lee TY, Hwang GY, Kao CH, Chen JK. Immunolocalization of high-density lipoproteins in arterial walls of rats. Atherosclerosis. 142: 269-77. PMID 10030377 DOI: 10.1016/S0021-9150(98)00238-X  0.456
1996 Byun Y, Wang T, Kim JS, Yang VC. Optimization and assessment of the in vivo efficacy of a heparin removing bio-reactor using mathematical modeling. Asaio Journal (American Society For Artificial Internal Organs : 1992). 42: M782-7. PMID 8944989 DOI: 10.1097/00002480-199609000-00096  0.571
1996 Guo X, Han IS, Yang VC, Meyerhoff ME. Homogeneous enzyme-based binding assay for studying glycosaminoglycan interactions with macromolecules and peptides. Analytical Biochemistry. 235: 153-60. PMID 8833323 DOI: 10.1006/Abio.1996.0107  0.304
1996 Wahr JA, Yun JH, Yang VC, Lee LM, Fu B, Meyerhoff ME. A new method of measuring heparin levels in whole blood by protamine titration using a heparin-responsive electrochemical sensor. Journal of Cardiothoracic and Vascular Anesthesia. 10: 447-50. PMID 8776635 DOI: 10.1016/S1053-0770(05)80002-3  0.488
1995 Yun JH, Lee LM, Wahr JA, Fu B, Meyerhoff ME, Yang VC. Clinical application of disposable heparin sensors. Blood heparin measurements during open heart surgery. Asaio Journal (American Society For Artificial Internal Organs : 1992). 41: M661-4. PMID 8573887 DOI: 10.1097/00002480-199507000-00093  0.441
1988 Bernstein J, Yang VC, Cooney CL, Langer R. Immobilized heparin lyase system for blood deheparinization Methods in Enzymology. 137: 515-529. PMID 3374357 DOI: 10.1016/0076-6879(88)37048-5  0.392
1986 Yang VC, Bernstein H, Cooney CL, Kadam JC, Langer R. Removal of the anticoagulant activities of the low molecular weight heparin fractions and fragments with flavobacterial heparinase Thrombosis Research. 44: 599-610. PMID 3810562 DOI: 10.1016/0049-3848(86)90162-3  0.399
1985 Yang VC, Morgan L, McCarty MT, Langer R. Isoelectric points of the polysaccharide-degrading enzymes in Flavobacterium heparinum Carbohydrate Research. 143: 294-299. PMID 4084918 DOI: 10.1016/S0008-6215(00)90723-7  0.347
1985 Yang VC, Turcotte JG, Steim JM. Biophysical properties of cytidine diphosphate diacylglycerol in solution. Biochimica Et Biophysica Acta. 834: 364-75. PMID 3995072 DOI: 10.1016/0005-2760(85)90010-4  0.645
1982 Yang VC, Turcotte JG, Steim JM. Physical properties of arabinofuranosylcytosine diphosphate diacylglycerol, an antitumor liponucleotide. Biochimica Et Biophysica Acta. 689: 375-84. PMID 7115716 DOI: 10.1016/0005-2736(82)90272-3  0.64
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