Laurel L. Lenz - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Immunology, Microbiology Biology

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bortell N, Aguilera ER, Lenz LL. Pulmonary insults exacerbate susceptibility to oral Listeria monocytogenes infection through the production of IL-10 by NK cells. Plos Pathogens. 17: e1009531. PMID 33878120 DOI: 10.1371/journal.ppat.1009531  0.404
2020 Eshleman EM, Bortell N, McDermott DS, Crisler WJ, Lenz LL. Myeloid cell responsiveness to interferon-gamma is sufficient for initial resistance to . Current Research in Immunology. 1: 1-9. PMID 34337387 DOI: 10.1016/j.crimmu.2020.01.001  0.475
2020 Larson SR, Bortell N, Illies A, Crisler WJ, Matsuda JL, Lenz LL. Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection. Frontiers in Immunology. 11: 590266. PMID 33363536 DOI: 10.3389/fimmu.2020.590266  0.436
2020 Clark SE, Schmidt RL, Aguilera ER, Lenz LL. IL-10-producing NK cells exacerbate sublethal Streptococcus pneumoniae infection in the lung. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 32634590 DOI: 10.1016/J.Trsl.2020.07.001  0.473
2020 Walker MM, Kim S, Crisler WJ, Nguyen K, Lenz LL, Cambier JC, Getahun A. Selective Loss of Responsiveness to Exogenous but Not Endogenous Cyclic-Dinucleotides in Mice Expressing STING-R231H. Frontiers in Immunology. 11: 238. PMID 32153571 DOI: 10.3389/Fimmu.2020.00238  0.437
2020 Aguilera ER, Lenz LL. Inflammation as a Modulator of Host Susceptibility to Pulmonary Influenza, Pneumococcal, and Co-Infections. Frontiers in Immunology. 11: 105. PMID 32117259 DOI: 10.3389/Fimmu.2020.00105  0.475
2020 Eshleman EM, Bortell N, McDermott DS, Crisler WJ, Lenz LL. Myeloid cell responsiveness to interferon-gamma is sufficient for initial resistance to Listeria monocytogenes Current Research in Immunology. 1: 1-9. DOI: 10.1016/j.crimmu.2020.01.001  0.359
2019 Yang C, McDermot DS, Pasricha S, Bedoui S, Lenz LL, van Driel IR, Hartland EL. IFNγ receptor down-regulation facilitates Legionella survival in alveolar macrophages. Journal of Leukocyte Biology. PMID 31793076 DOI: 10.1002/Jlb.4Ma1019-152R  0.529
2019 Crisler WJ, Eshleman EM, Lenz LL. Ligand-induced IFNGR1 down-regulation calibrates myeloid cell IFNγ responsiveness. Life Science Alliance. 2. PMID 31585982 DOI: 10.26508/lsa.201900447  0.503
2019 Clark SE, Burrack KS, Jameson SC, Hamilton SE, Lenz LL. NK Cell IL-10 Production Requires IL-15 and IL-10 Driven STAT3 Activation. Frontiers in Immunology. 10: 2087. PMID 31552035 DOI: 10.3389/Fimmu.2019.02087  0.365
2018 Soderborg TK, Clark SE, Mulligan CE, Janssen RC, Babcock L, Ir D, Lemas DJ, Johnson LK, Weir T, Lenz LL, Frank DN, Hernandez TL, Kuhn KA, D'Alessandro A, Barbour LA, et al. The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD. Nature Communications. 9: 4462. PMID 30367045 DOI: 10.1038/S41467-018-06929-0  0.303
2018 Alper S, Lenz LL. Editorial overview: Tuning the innate immune response to pathogens. Current Opinion in Immunology. 54: vi-ix. PMID 30342707 DOI: 10.1016/J.Coi.2018.10.001  0.441
2018 Crisler WJ, Lenz LL. Crosstalk between type I and II interferons in regulation of myeloid cell responses during bacterial infection. Current Opinion in Immunology. 54: 35-41. PMID 29886270 DOI: 10.1016/J.Coi.2018.05.014  0.612
2018 Clark SE, Schmidt RL, McDermott DS, Lenz LL. A Batf3/Nlrp3/IL-18 Axis Promotes Natural Killer Cell IL-10 Production during Listeria monocytogenes Infection. Cell Reports. 23: 2582-2594. PMID 29847790 DOI: 10.1016/J.Celrep.2018.04.106  0.392
2017 Eshleman EM, Delgado C, Kearney SJ, Friedman RS, Lenz LL. Down regulation of macrophage IFNGR1 exacerbates systemic L. monocytogenes infection. Plos Pathogens. 13: e1006388. PMID 28542482 DOI: 10.1371/Journal.Ppat.1006388  0.81
2017 Smith C, Jalbert E, de Almeida V, Canniff J, Lenz LL, Mussi-Pinhata MM, Cohen RA, Yu Q, Amaral FR, Pinto J, Alarcon JO, Siberry G, Weinberg A. Altered Natural Killer Cell Function in HIV-Exposed Uninfected Infants. Frontiers in Immunology. 8: 470. PMID 28484464 DOI: 10.3389/Fimmu.2017.00470  0.302
2016 Clark SE, Filak HC, Guthrie BS, Schmidt RL, Jamieson A, Merkel P, Knight V, Cole CM, Raulet DH, Lenz LL. Bacterial Manipulation of NK Cell Regulatory Activity Increases Susceptibility to Listeria monocytogenes Infection. Plos Pathogens. 12: e1005708. PMID 27295349 DOI: 10.1371/Journal.Ppat.1005708  0.528
2016 Mills CD, Lenz LL, Harris RA. A Breakthrough: Macrophage-Directed Cancer Immunotherapy. Cancer Research. PMID 26772756 DOI: 10.1158/0008-5472.Can-15-1737  0.364
2015 Mills CD, Lenz LL, Ley K. Macrophages at the fork in the road to health or disease. Frontiers in Immunology. 6: 59. PMID 25762997 DOI: 10.3389/Fimmu.2015.00059  0.424
2014 Mills CD, Thomas AC, Lenz LL, Munder M. Macrophage: SHIP of Immunity. Frontiers in Immunology. 5: 620. PMID 25538705 DOI: 10.3389/Fimmu.2014.00620  0.431
2014 Eshleman EM, Lenz LL. Type I interferons in bacterial infections: taming of myeloid cells and possible implications for autoimmunity. Frontiers in Immunology. 5: 431. PMID 25309533 DOI: 10.3389/Fimmu.2014.00431  0.614
2014 Czaja CA, Merkel PA, Chan ED, Lenz LL, Wolf ML, Alam R, Frankel SK, Fischer A, Gogate S, Perez-Velez CM, Knight V. Rituximab as successful adjunct treatment in a patient with disseminated nontuberculous mycobacterial infection due to acquired anti-interferon-γ autoantibody. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: e115-8. PMID 24336756 DOI: 10.1093/Cid/Cit809  0.496
2013 Kearney SJ, Delgado C, Eshleman EM, Hill KK, O'Connor BP, Lenz LL. Type I IFNs downregulate myeloid cell IFN-γ receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription. Journal of Immunology (Baltimore, Md. : 1950). 191: 3384-92. PMID 23935197 DOI: 10.4049/Jimmunol.1203510  0.792
2013 Kearney S, Delgado C, Lenz LL. Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infections. Immunologic Research. 55: 187-200. PMID 22983898 DOI: 10.1007/S12026-012-8362-Y  0.805
2013 Kearney SJ, Delgado C, Eshleman EM, Hill KK, O’Connor BP, Lenz LL. 142 Cytokine. 63: 276. DOI: 10.1016/J.Cyto.2013.06.145  0.802
2012 Schmidt RL, Lenz LL. Distinct licensing of IL-18 and IL-1β secretion in response to NLRP3 inflammasome activation. Plos One. 7: e45186. PMID 23028835 DOI: 10.1371/Journal.Pone.0045186  0.334
2012 Williams MA, Schmidt RL, Lenz LL. Early events regulating immunity and pathogenesis during Listeria monocytogenes infection. Trends in Immunology. 33: 488-95. PMID 22677184 DOI: 10.1016/J.It.2012.04.007  0.525
2012 Cole C, Thomas S, Filak H, Henson PM, Lenz LL. Nitric oxide increases susceptibility of Toll-like receptor-activated macrophages to spreading Listeria monocytogenes. Immunity. 36: 807-20. PMID 22542147 DOI: 10.1016/J.Immuni.2012.03.011  0.532
2012 Rayamajhi M, Delgado C, Condon TV, Riches DW, Lenz LL. Lung B cells promote early pathogen dissemination and hasten death from inhalation anthrax. Mucosal Immunology. 5: 444-54. PMID 22472773 DOI: 10.1038/Mi.2012.21  0.664
2011 Schmidt RL, Filak HC, Lemon JD, Potter TA, Lenz LL. A LysM and SH3-domain containing region of the Listeria monocytogenes p60 protein stimulates accessory cells to promote activation of host NK cells. Plos Pathogens. 7: e1002368. PMID 22072975 DOI: 10.1371/Journal.Ppat.1002368  0.466
2011 Jin L, Hill KK, Filak H, Mogan J, Knowles H, Zhang B, Perraud AL, Cambier JC, Lenz LL. MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP. Journal of Immunology (Baltimore, Md. : 1950). 187: 2595-601. PMID 21813776 DOI: 10.4049/Jimmunol.1100088  0.613
2011 Knowles H, Heizer JW, Li Y, Chapman K, Ogden CA, Andreasen K, Shapland E, Kucera G, Mogan J, Humann J, Lenz LL, Morrison AD, Perraud AL. Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes. Proceedings of the National Academy of Sciences of the United States of America. 108: 11578-83. PMID 21709234 DOI: 10.1073/Pnas.1010678108  0.775
2011 Rayamajhi M, Redente EF, Condon TV, Gonzalez-Juarrero M, Riches DW, Lenz LL. Non-surgical intratracheal instillation of mice with analysis of lungs and lung draining lymph nodes by flow cytometry. Journal of Visualized Experiments : Jove. PMID 21587154 DOI: 10.3791/2702  0.631
2011 Boudreau JE, Stephenson KB, Wang F, Ashkar AA, Mossman KL, Lenz LL, Rosenthal KL, Bramson JL, Lichty BD, Wan Y. IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells. Cancer Research. 71: 2497-506. PMID 21307131 DOI: 10.1158/0008-5472.Can-10-3025  0.487
2010 Rayamajhi M, Humann J, Kearney S, Hill KK, Lenz LL. Antagonistic crosstalk between type I and II interferons and increased host susceptibility to bacterial infections. Virulence. 1: 418-22. PMID 21178482 DOI: 10.4161/Viru.1.5.12787  0.739
2010 Jin L, Lenz LL, Cambier JC. Cellular reactive oxygen species inhibit MPYS induction of IFNβ. Plos One. 5: e15142. PMID 21170271 DOI: 10.1371/Journal.Pone.0015142  0.355
2010 Humann J, Lenz LL. Activation of naive NK cells in response to Listeria monocytogenes requires IL-18 and contact with infected dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 5172-8. PMID 20351186 DOI: 10.4049/Jimmunol.0903759  0.776
2010 Rayamajhi M, Humann J, Penheiter K, Andreasen K, Lenz LL. Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma. The Journal of Experimental Medicine. 207: 327-37. PMID 20123961 DOI: 10.1084/Jem.20091746  0.816
2009 Humann J, Lenz LL. Bacterial peptidoglycan degrading enzymes and their impact on host muropeptide detection. Journal of Innate Immunity. 1: 88-97. PMID 19319201 DOI: 10.1159/000181181  0.744
2009 Lenz LL. CD5 sweetens lymphocyte responses. Proceedings of the National Academy of Sciences of the United States of America. 106: 1303-4. PMID 19174525 DOI: 10.1073/Pnas.0812579106  0.462
2008 Lenz LL, Huang WA, Zhou C, Li Z, Calendar R. Stable integration vector for nutrient broth-based selection of attenuated Listeria monocytogenes strains with recombinant antigen expression. Clinical and Vaccine Immunology : Cvi. 15: 1414-9. PMID 18650400 DOI: 10.1128/Cvi.00208-08  0.372
2008 Lenz LL, Andrews-Polymenis HL. Silencing the alarm: insights into the interaction between host and pathogen. Conference on Microbial Pathogenesis: Mechanisms of Infectious Disease. Embo Reports. 9: 27-32. PMID 18084188 DOI: 10.1038/Sj.Embor.7401127  0.496
2008 Noor S, Goldfine H, Tucker DE, Suram S, Lenz LL, Akira S, Uematsu S, Girotti M, Bonventre JV, Breuel K, Williams DL, Leslie CC. Activation of cytosolic phospholipase A2alpha in resident peritoneal macrophages by Listeria monocytogenes involves listeriolysin O and TLR2. The Journal of Biological Chemistry. 283: 4744-55. PMID 18083708 DOI: 10.1074/jbc.M709956200  0.395
2007 Humann J, Bjordahl R, Andreasen K, Lenz LL. Expression of the p60 autolysin enhances NK cell activation and is required for listeria monocytogenes expansion in IFN-gamma-responsive mice. Journal of Immunology (Baltimore, Md. : 1950). 178: 2407-14. PMID 17277147 DOI: 10.4049/Jimmunol.178.4.2407  0.807
2007 Muraille E, Narni-Mancinelli E, Gounon P, Bassand D, Glaichenhaus N, Lenz LL, Lauvau G. Cytosolic expression of SecA2 is a prerequisite for long-term protective immunity. Cellular Microbiology. 9: 1445-54. PMID 17244189 DOI: 10.1111/J.1462-5822.2007.00883.X  0.517
2005 Arrunategui-Correa V, Lenz L, Kim HS. CD1d-independent regulation of NKT cell migration and cytokine production upon Listeria monocytogenes infection. Cellular Immunology. 232: 38-48. PMID 15922714 DOI: 10.1016/J.Cellimm.2005.01.009  0.485
2004 Diehl GE, Yue HH, Hsieh K, Kuang AA, Ho M, Morici LA, Lenz LL, Cado D, Riley LW, Winoto A. TRAIL-R as a negative regulator of innate immune cell responses. Immunity. 21: 877-89. PMID 15589175 DOI: 10.1016/j.immuni.2004.11.008  0.337
2003 Ploss A, Lauvau G, Contos B, Kerksiek KM, Guirnalda PD, Leiner I, Lenz LL, Bevan MJ, Pamer EG. Promiscuity of MHC class Ib-restricted T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 171: 5948-55. PMID 14634106 DOI: 10.4049/Jimmunol.171.11.5948  0.367
2003 Lenz LL, Mohammadi S, Geissler A, Portnoy DA. SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 12432-7. PMID 14527997 DOI: 10.1073/Pnas.2133653100  0.484
2002 Lenz LL, Portnoy DA. Identification of a second Listeria secA gene associated with protein secretion and the rough phenotype. Molecular Microbiology. 45: 1043-56. PMID 12180923 DOI: 10.1046/J.1365-2958.2002.03072.X  0.33
2001 Auerbuch V, Lenz LL, Portnoy DA. Development of a competitive index assay to evaluate the virulence of Listeria monocytogenes actA mutants during primary and secondary infection of mice. Infection and Immunity. 69: 5953-7. PMID 11500481 DOI: 10.1128/Iai.69.9.5953-5957.2001  0.354
2000 Lenz LL, Butz EA, Bevan MJ. Requirements for bone marrow-derived antigen-presenting cells in priming cytotoxic T cell responses to intracellular pathogens Journal of Experimental Medicine. 192: 1135-1142. PMID 11034603 DOI: 10.1084/Jem.192.8.1135  0.472
1998 Princiotta MF, Lenz LL, Bevan MJ, Staerz UD. H2-M3 restricted presentation of a listeria-derived leader peptide Journal of Experimental Medicine. 187: 1711-1719. PMID 9584149 DOI: 10.1084/Jem.187.10.1711  0.4
1997 Lenz LL, Bevan MJ. CTL responses to H2-M3-restricted Listeria epitopes Immunological Reviews. 158: 115-121. PMID 9314079 DOI: 10.1111/J.1600-065X.1997.Tb00997.X  0.366
1996 Harty JT, Lenz LL, Bevan MJ. Primary and secondary immune responses to Listeria monocytogenes Current Opinion in Immunology. 8: 526-530. PMID 8794012 DOI: 10.1016/S0952-7915(96)80041-0  0.472
1996 Lenz LL, Dere B, Bevan MJ. Identification of an H2-M3-Restricted listeria epitope: Implications for antigen presentation by M3 Immunity. 5: 63-72. PMID 8758895 DOI: 10.1016/S1074-7613(00)80310-6  0.308
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