| Year |
Citation |
Score |
| 2019 |
Damiani C, Maspero D, Di Filippo M, Colombo R, Pescini D, Graudenzi A, Westerhoff HV, Alberghina L, Vanoni M, Mauri G. Integration of single-cell RNA-seq data into population models to characterize cancer metabolism. Plos Computational Biology. 15: e1006733. PMID 30818329 DOI: 10.1371/Journal.Pcbi.1006733 |
0.309 |
|
| 2018 |
Marozava S, Vargas-López R, Tian Y, Merl-Pham J, Braster M, Meckenstock RU, Smidt H, Röling WFM, Westerhoff HV. Metabolic flexibility of a prospective bioremediator: Desulfitobacterium hafniense Y51 challenged in chemostats. Environmental Microbiology. PMID 29921035 DOI: 10.1111/1462-2920.14295 |
0.319 |
|
| 2018 |
Wright Muelas M, Ortega F, Breitling R, Bendtsen C, Westerhoff HV. Rational cell culture optimization enhances experimental reproducibility in cancer cells. Scientific Reports. 8: 3029. PMID 29445172 DOI: 10.1038/S41598-018-21050-4 |
0.314 |
|
| 2017 |
Damiani C, Colombo R, Gaglio D, Mastroianni F, Pescini D, Westerhoff HV, Mauri G, Vanoni M, Alberghina L. A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect. Plos Computational Biology. 13: e1005758. PMID 28957320 DOI: 10.1371/Journal.Pcbi.1005758 |
0.35 |
|
| 2017 |
Abudukelimu A, Mondeel TDGA, Barberis M, Westerhoff HV. Learning to read and write in evolution: from static pseudoenzymes and pseudosignalers to dynamic gear shifters. Biochemical Society Transactions. 45: 635-652. PMID 28620026 DOI: 10.1042/Bst20160281 |
0.341 |
|
| 2017 |
Zhang Y, Kouril T, Snoep JL, Siebers B, Barberis M, Westerhoff HV. The Peculiar Glycolytic Pathway in Hyperthermophylic Archaea: Understanding Its Whims by Experimentation In Silico. International Journal of Molecular Sciences. 18. PMID 28425930 DOI: 10.3390/Ijms18040876 |
0.341 |
|
| 2017 |
Haanstra JR, Gerding A, Dolga AM, Sorgdrager FJ, Buist-Homan M, du Toit F, Faber KN, Holzhütter HG, Szöör B, Matthews KR, Snoep JL, Westerhoff HV, Bakker BM. Targeting pathogen metabolism without collateral damage to the host. Scientific Reports. 7: 40406. PMID 28084422 DOI: 10.1038/Srep40406 |
0.305 |
|
| 2016 |
He F, Murabito E, Westerhoff HV. Synthetic biology and regulatory networks: where metabolic systems biology meets control engineering. Journal of the Royal Society, Interface / the Royal Society. 13. PMID 27075000 DOI: 10.1098/Rsif.2015.1046 |
0.302 |
|
| 2015 |
Sellick CA, Croxford AS, Maqsood AR, Stephens GM, Westerhoff HV, Goodacre R, Dickson AJ. Metabolite profiling of CHO cells: Molecular reflections of bioprocessing effectiveness. Biotechnology Journal. 10: 1434-45. PMID 26198903 DOI: 10.1002/Biot.201400664 |
0.332 |
|
| 2014 |
Murabito E, Verma M, Bekker M, Bellomo D, Westerhoff HV, Teusink B, Steuer R. Monte-Carlo modeling of the central carbon metabolism of Lactococcus lactis: insights into metabolic regulation. Plos One. 9: e106453. PMID 25268481 DOI: 10.1371/Journal.Pone.0106453 |
0.373 |
|
| 2013 |
van Heeswijk WC, Westerhoff HV, Boogerd FC. Nitrogen assimilation in Escherichia coli: putting molecular data into a systems perspective. Microbiology and Molecular Biology Reviews : Mmbr. 77: 628-95. PMID 24296575 DOI: 10.1128/Mmbr.00025-13 |
0.341 |
|
| 2013 |
He F, Fromion V, Westerhoff HV. (Im)Perfect robustness and adaptation of metabolic networks subject to metabolic and gene-expression regulation: marrying control engineering with metabolic control analysis. Bmc Systems Biology. 7: 131. PMID 24261908 DOI: 10.1186/1752-0509-7-131 |
0.356 |
|
| 2013 |
Kouril T, Esser D, Kort J, Westerhoff HV, Siebers B, Snoep JL. Intermediate instability at high temperature leads to low pathway efficiency for an in vitro reconstituted system of gluconeogenesis in Sulfolobus solfataricus. The Febs Journal. 280: 4666-80. PMID 23865479 DOI: 10.1111/Febs.12438 |
0.334 |
|
| 2013 |
Mensonides FI, Bakker BM, Cremazy F, Messiha HL, Mendes P, Boogerd FC, Westerhoff HV. A new regulatory principle for in vivo biochemistry: pleiotropic low affinity regulation by the adenine nucleotides--illustrated for the glycolytic enzymes of Saccharomyces cerevisiae. Febs Letters. 587: 2860-7. PMID 23856461 DOI: 10.1016/J.Febslet.2013.07.013 |
0.348 |
|
| 2013 |
Smallbone K, Messiha HL, Carroll KM, Winder CL, Malys N, Dunn WB, Murabito E, Swainston N, Dada JO, Khan F, Pir P, Simeonidis E, Spasić I, Wishart J, Weichart D, ... ... Westerhoff HV, et al. A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes. Febs Letters. 587: 2832-41. PMID 23831062 DOI: 10.1016/J.Febslet.2013.06.043 |
0.358 |
|
| 2013 |
Geenen S, du Preez FB, Snoep JL, Foster AJ, Sarda S, Kenna JG, Wilson ID, Westerhoff HV. Glutathione metabolism modeling: a mechanism for liver drug-robustness and a new biomarker strategy. Biochimica Et Biophysica Acta. 1830: 4943-59. PMID 23643929 DOI: 10.1016/J.Bbagen.2013.04.014 |
0.362 |
|
| 2013 |
Thiele I, Swainston N, Fleming RM, Hoppe A, Sahoo S, Aurich MK, Haraldsdottir H, Mo ML, Rolfsson O, Stobbe MD, Thorleifsson SG, Agren R, Bölling C, Bordel S, Chavali AK, ... ... Westerhoff HV, et al. A community-driven global reconstruction of human metabolism. Nature Biotechnology. 31: 419-25. PMID 23455439 DOI: 10.1038/Nbt.2488 |
0.304 |
|
| 2013 |
Quinton-Tulloch MJ, Bruggeman FJ, Snoep JL, Westerhoff HV. Trade-off of dynamic fragility but not of robustness in metabolic pathways in silico. The Febs Journal. 280: 160-73. PMID 23121761 DOI: 10.1111/Febs.12057 |
0.344 |
|
| 2013 |
Verma M, Zakhartsev M, Reuss M, Westerhoff HV. 'Domino' systems biology and the 'A' of ATP. Biochimica Et Biophysica Acta. 1827: 19-29. PMID 23031542 DOI: 10.1016/J.Bbabio.2012.09.014 |
0.35 |
|
| 2012 |
García-Contreras R, Vos P, Westerhoff HV, Boogerd FC. Why in vivo may not equal in vitro - new effectors revealed by measurement of enzymatic activities under the same in vivo-like assay conditions. The Febs Journal. 279: 4145-59. PMID 22978366 DOI: 10.1111/Febs.12007 |
0.308 |
|
| 2012 |
Jozefczuk J, Kashofer K, Ummanni R, Henjes F, Rehman S, Geenen S, Wruck W, Regenbrecht C, Daskalaki A, Wierling C, Turano P, Bertini I, Korf U, Zatloukal K, Westerhoff HV, et al. A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells. Frontiers in Physiology. 3: 339. PMID 22969728 DOI: 10.3389/Fphys.2012.00339 |
0.302 |
|
| 2012 |
Rehman S, Xu Y, Dunn WB, Day PJ, Westerhoff HV, Goodacre R, Bayat A. Dupuytren's disease metabolite analyses reveals alterations following initial short-term fibroblast culturing. Molecular Biosystems. 8: 2274-88. PMID 22772395 DOI: 10.1039/C2Mb25173F |
0.325 |
|
| 2012 |
Adamczyk M, Westerhoff HV. Engineering of self-sustaining systems: substituting the yeast glucose transporter plus hexokinase for the Lactococcus lactis phosphotransferase system in a Lactococcus lactis network in silico. Biotechnology Journal. 7: 877-83. PMID 22700394 DOI: 10.1002/Biot.201100314 |
0.303 |
|
| 2012 |
van Eunen K, Kiewiet JA, Westerhoff HV, Bakker BM. Testing biochemistry revisited: how in vivo metabolism can be understood from in vitro enzyme kinetics. Plos Computational Biology. 8: e1002483. PMID 22570597 DOI: 10.1371/Journal.Pcbi.1002483 |
0.354 |
|
| 2012 |
Geenen S, Taylor PN, Snoep JL, Wilson ID, Kenna JG, Westerhoff HV. Systems biology tools for toxicology. Archives of Toxicology. 86: 1251-71. PMID 22569772 DOI: 10.1007/S00204-012-0857-8 |
0.31 |
|
| 2012 |
Geenen S, du Preez FB, Reed M, Nijhout HF, Kenna JG, Wilson ID, Westerhoff HV, Snoep JL. A mathematical modelling approach to assessing the reliability of biomarkers of glutathione metabolism. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 46: 233-43. PMID 21888969 DOI: 10.1016/J.Ejps.2011.08.017 |
0.321 |
|
| 2011 |
van Eunen K, Rossell S, Bouwman J, Westerhoff HV, Bakker BM. Quantitative analysis of flux regulation through hierarchical regulation analysis. Methods in Enzymology. 500: 571-95. PMID 21943915 DOI: 10.1016/B978-0-12-385118-5.00027-X |
0.332 |
|
| 2011 |
Adamczyk M, van Eunen K, Bakker BM, Westerhoff HV. Enzyme kinetics for systems biology when, why and how. Methods in Enzymology. 500: 233-57. PMID 21943901 DOI: 10.1016/B978-0-12-385118-5.00013-X |
0.303 |
|
| 2011 |
Nilapwar SM, Nardelli M, Westerhoff HV, Verma M. Absorption spectroscopy. Methods in Enzymology. 500: 59-75. PMID 21943892 DOI: 10.1016/B978-0-12-385118-5.00004-9 |
0.319 |
|
| 2011 |
Haanstra JR, Kerkhoven EJ, van Tuijl A, Blits M, Wurst M, van Nuland R, Albert MA, Michels PA, Bouwman J, Clayton C, Westerhoff HV, Bakker BM. A domino effect in drug action: from metabolic assault towards parasite differentiation. Molecular Microbiology. 79: 94-108. PMID 21166896 DOI: 10.1111/J.1365-2958.2010.07435.X |
0.302 |
|
| 2011 |
Murabito E, Smallbone K, Swinton J, Westerhoff HV, Steuer R. A probabilistic approach to identify putative drug targets in biochemical networks. Journal of the Royal Society, Interface / the Royal Society. 8: 880-95. PMID 21123256 DOI: 10.1098/Rsif.2010.0540 |
0.324 |
|
| 2010 |
Canelas AB, Harrison N, Fazio A, Zhang J, Pitkänen JP, van den Brink J, Bakker BM, Bogner L, Bouwman J, Castrillo JI, Cankorur A, Chumnanpuen P, Daran-Lapujade P, Dikicioglu D, van Eunen K, ... ... Westerhoff H, et al. Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains. Nature Communications. 1: 145. PMID 21266995 DOI: 10.1038/Ncomms1150 |
0.304 |
|
| 2010 |
Li P, Dada JO, Jameson D, Spasic I, Swainston N, Carroll K, Dunn W, Khan F, Malys N, Messiha HL, Simeonidis E, Weichart D, Winder C, Wishart J, Broomhead DS, ... ... Westerhoff HV, et al. Systematic integration of experimental data and models in systems biology. Bmc Bioinformatics. 11: 582. PMID 21114840 DOI: 10.1186/1471-2105-11-582 |
0.313 |
|
| 2010 |
Simeonidis E, Murabito E, Smallbone K, Westerhoff HV. Why does yeast ferment? A flux balance analysis study. Biochemical Society Transactions. 38: 1225-9. PMID 20863289 DOI: 10.1042/Bst0381225 |
0.33 |
|
| 2010 |
Moreno-Sánchez R, Saavedra E, Rodríguez-Enríquez S, Gallardo-Pérez JC, Quezada H, Westerhoff HV. Metabolic control analysis indicates a change of strategy in the treatment of cancer. Mitochondrion. 10: 626-39. PMID 20599628 DOI: 10.1016/J.Mito.2010.06.002 |
0.352 |
|
| 2010 |
van Eunen K, Dool P, Canelas AB, Kiewiet J, Bouwman J, van Gulik WM, Westerhoff HV, Bakker BM. Time-dependent regulation of yeast glycolysis upon nitrogen starvation depends on cell history. Iet Systems Biology. 4: 157-68. PMID 20232995 DOI: 10.1049/Iet-Syb.2009.0025 |
0.327 |
|
| 2010 |
Conradie R, Bruggeman FJ, Ciliberto A, Csikász-Nagy A, Novák B, Westerhoff HV, Snoep JL. Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex. The Febs Journal. 277: 357-67. PMID 20015233 DOI: 10.1111/J.1742-4658.2009.07473.X |
0.317 |
|
| 2009 |
Härdin HM, Zagaris A, Krab K, Westerhoff HV. Simplified yet highly accurate enzyme kinetics for cases of low substrate concentrations. The Febs Journal. 276: 5491-506. PMID 19725885 DOI: 10.1111/J.1742-4658.2009.07233.X |
0.332 |
|
| 2009 |
van Eunen K, Bouwman J, Lindenbergh A, Westerhoff HV, Bakker BM. Time-dependent regulation analysis dissects shifts between metabolic and gene-expression regulation during nitrogen starvation in baker's yeast. The Febs Journal. 276: 5521-36. PMID 19691496 DOI: 10.1111/J.1742-4658.2009.07235.X |
0.365 |
|
| 2009 |
Westerhoff HV, Kelt DB. Matrix method for determining steps most rate-limiting to metabolic fluxes in biotechnological processes. 1987. Biotechnology and Bioengineering. 104: 1-9. PMID 19623536 DOI: 10.1002/Bit.22458 |
0.366 |
|
| 2009 |
Albers SV, Birkeland NK, Driessen AJ, Gertig S, Haferkamp P, Klenk HP, Kouril T, Manica A, Pham TK, Ruoff P, Schleper C, Schomburg D, Sharkey KJ, Siebers B, Sierocinski P, ... ... Westerhoff HV, et al. SulfoSYS (Sulfolobus Systems Biology): towards a silicon cell model for the central carbohydrate metabolism of the archaeon Sulfolobus solfataricus under temperature variation. Biochemical Society Transactions. 37: 58-64. PMID 19143602 DOI: 10.1042/Bst0370058 |
0.331 |
|
| 2009 |
Snoep JL, Arfman N, Yomano LP, Westerhoff HV, Conway T, Ingram LO. Control of glycolytic flux in Zymomonas mobilis by glucose 6-phosphate dehydrogenase activity. Biotechnology and Bioengineering. 51: 190-7. PMID 18624328 DOI: 10.1002/(Sici)1097-0290(19960720)51:2<190::Aid-Bit8>3.0.Co;2-E |
0.325 |
|
| 2009 |
Westerhoff HV, Kolodkin A, Conradie R, Wilkinson SJ, Bruggeman FJ, Krab K, van Schuppen JH, Hardin H, Bakker BM, Moné MJ, Rybakova KN, Eijken M, van Leeuwen HJ, Snoep JL. Systems biology towards life in silico: mathematics of the control of living cells. Journal of Mathematical Biology. 58: 7-34. PMID 18278498 DOI: 10.1007/S00285-008-0160-8 |
0.373 |
|
| 2008 |
Bruggeman FJ, Snoep JL, Westerhoff HV. Control, responses and modularity of cellular regulatory networks: a control analysis perspective. Iet Systems Biology. 2: 397-410. PMID 19045835 DOI: 10.1049/Iet-Syb:20070065 |
0.349 |
|
| 2008 |
Haanstra JR, van Tuijl A, Kessler P, Reijnders W, Michels PA, Westerhoff HV, Parsons M, Bakker BM. Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes. Proceedings of the National Academy of Sciences of the United States of America. 105: 17718-23. PMID 19008351 DOI: 10.1073/Pnas.0806664105 |
0.341 |
|
| 2008 |
Herrgård MJ, Swainston N, Dobson P, Dunn WB, Arga KY, Arvas M, Blüthgen N, Borger S, Costenoble R, Heinemann M, Hucka M, Le Novère N, Li P, Liebermeister W, Mo ML, ... ... Westerhoff HV, et al. A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. Nature Biotechnology. 26: 1155-60. PMID 18846089 DOI: 10.1038/Nbt1492 |
0.303 |
|
| 2008 |
Oláh J, Klivényi P, Gardián G, Vécsei L, Orosz F, Kovacs GG, Westerhoff HV, Ovádi J. Increased glucose metabolism and ATP level in brain tissue of Huntington's disease transgenic mice. The Febs Journal. 275: 4740-55. PMID 18721135 DOI: 10.1111/J.1742-4658.2008.06612.X |
0.345 |
|
| 2008 |
Westerhoff HV. Signalling control strength. Journal of Theoretical Biology. 252: 555-67. PMID 18222488 DOI: 10.1016/J.Jtbi.2007.11.035 |
0.355 |
|
| 2008 |
Rossell S, Lindenbergh A, van der Weijden CC, Kruckeberg AL, van Eunen K, Westerhoff HV, Bakker BM. Mixed and diverse metabolic and gene-expression regulation of the glycolytic and fermentative pathways in response to a HXK2 deletion in Saccharomyces cerevisiae. Fems Yeast Research. 8: 155-64. PMID 17662056 DOI: 10.1111/J.1567-1364.2007.00282.X |
0.345 |
|
| 2007 |
Daran-Lapujade P, Rossell S, van Gulik WM, Luttik MA, de Groot MJ, Slijper M, Heck AJ, Daran JM, de Winde JH, Westerhoff HV, Pronk JT, Bakker BM. The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels. Proceedings of the National Academy of Sciences of the United States of America. 104: 15753-8. PMID 17898166 DOI: 10.1073/Pnas.0707476104 |
0.351 |
|
| 2007 |
Ruoff P, Zakhartsev M, Westerhoff HV. Temperature compensation through systems biology. The Febs Journal. 274: 940-50. PMID 17227386 DOI: 10.1111/J.1742-4658.2007.05641.X |
0.305 |
|
| 2007 |
Röling WF, van Breukelen BM, Bruggeman FJ, Westerhoff HV. Ecological control analysis: being(s) in control of mass flux and metabolite concentrations in anaerobic degradation processes. Environmental Microbiology. 9: 500-11. PMID 17222148 DOI: 10.1111/J.1462-2920.2006.01167.X |
0.322 |
|
| 2007 |
Hornberg JJ, Bruggeman FJ, Bakker BM, Westerhoff HV. Metabolic control analysis to identify optimal drug targets. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. ProgrèS Des Recherches Pharmaceutiques. 64: 171, 173-89. PMID 17195475 DOI: 10.1007/978-3-7643-7567-6_7 |
0.357 |
|
| 2007 |
Ciapaite J, Bakker SJ, Van Eikenhorst G, Wagner MJ, Teerlink T, Schalkwijk CG, Fodor M, Ouwens DM, Diamant M, Heine RJ, Westerhoff HV, Krab K. Functioning of oxidative phosphorylation in liver mitochondria of high-fat diet fed rats. Biochimica Et Biophysica Acta. 1772: 307-16. PMID 17184976 DOI: 10.1016/J.Bbadis.2006.10.018 |
0.301 |
|
| 2006 |
Ciapaite J, Bakker SJ, Diamant M, van Eikenhorst G, Heine RJ, Westerhoff HV, Krab K. Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects. Implications for a mechanism linking obesity and type 2 diabetes. The Febs Journal. 273: 5288-302. PMID 17059463 DOI: 10.1111/J.1742-4658.2006.05523.X |
0.326 |
|
| 2006 |
Blüthgen N, Bruggeman FJ, Legewie S, Herzel H, Westerhoff HV, Kholodenko BN. Effects of sequestration on signal transduction cascades. The Febs Journal. 273: 895-906. PMID 16478465 DOI: 10.1111/J.1742-4658.2006.05105.X |
0.312 |
|
| 2006 |
Rossell S, Van Der Weijden CC, Lindenbergh A, Van Tuijl A, Francke C, Bakker BM, Westerhoff HV. Unraveling the complexity of flux regulation: A new method demonstrated for nutrient starvation in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 103: 2166-2171. PMID 16467155 DOI: 10.1073/Pnas.0509831103 |
0.357 |
|
| 2006 |
Snoep JL, Bruggeman F, Olivier BG, Westerhoff HV. Towards building the silicon cell: a modular approach. Bio Systems. 83: 207-16. PMID 16242236 DOI: 10.1016/J.Biosystems.2005.07.006 |
0.316 |
|
| 2006 |
Westerhoff HV. Systems biology and the silicon cell: Order out of chaos Computer Aided Chemical Engineering. 21: 81-93. DOI: 10.1016/S1570-7946(06)80029-5 |
0.35 |
|
| 2005 |
Hornberg JJ, Binder B, Bruggeman FJ, Schoeberl B, Heinrich R, Westerhoff HV. Control of MAPK signalling: from complexity to what really matters. Oncogene. 24: 5533-42. PMID 16007170 DOI: 10.1038/Sj.Onc.1208817 |
0.317 |
|
| 2005 |
Bruggeman FJ, Boogerd FC, Westerhoff HV. The multifarious short-term regulation of ammonium assimilation of Escherichia coli: Dissection using an in silico replica Febs Journal. 272: 1965-1985. PMID 15819889 DOI: 10.1111/J.1742-4658.2005.04626.X |
0.361 |
|
| 2005 |
Rossell S, Van Der Weijden CC, Kruckeberg AL, Bakker BM, Westerhoff HV. Hierarchical and metabolic regulation of glucose influx in starved Saccharomyces cerevisiae Fems Yeast Research. 5: 611-619. PMID 15780660 DOI: 10.1016/J.Femsyr.2004.11.003 |
0.318 |
|
| 2005 |
Reijenga KA, Van Megen YMGA, Kooi BW, Bakker BM, Snoep JL, Van Verseveld HW, Westerhoff HV. Yeast glycolytic oscillations that are not controlled by a single oscillophore: A new definition of oscillophore strength Journal of Theoretical Biology. 232: 385-398. PMID 15572063 DOI: 10.1016/J.Jtbi.2004.08.019 |
0.347 |
|
| 2003 |
Peletier MA, Westerhoff HV, Kholodenko BN. Control of spatially heterogeneous and time-varying cellular reaction networks: A new summation law Journal of Theoretical Biology. 225: 477-487. PMID 14615206 DOI: 10.1016/S0022-5193(03)00289-3 |
0.324 |
|
| 2003 |
Francke C, Postma PW, Westerhoff HV, Blom JG, Peletier MA. Why the phosphotransferase system of Escherichia coli escapes diffusion limitation Biophysical Journal. 85: 612-622. PMID 12829515 DOI: 10.1016/S0006-3495(03)74505-6 |
0.306 |
|
| 2003 |
Getz WM, Westerhoff HV, Hofmeyr JHS, Snoep JL. Control analysis of trophic chains Ecological Modelling. 168: 153-171. DOI: 10.1016/S0304-3800(03)00208-4 |
0.309 |
|
| 2002 |
Koebmann BJ, Westerhoff HV, Snoep JL, Solem C, Pedersen MB, Nilsson D, Michelsen O, Jensen PR. The extent to which ATP demand controls the glycolytic flux depends strongly on the organism and conditions for growth Molecular Biology Reports. 29: 41-45. PMID 12241072 DOI: 10.1023/A:1020398117281 |
0.337 |
|
| 2002 |
Rossell S, Van Der Weijden CC, Kruckeberg A, Bakker BM, Westerhoff HV. Loss of fermentative capacity in baker's yeast can partly be explained by reduced glucose uptake capacity Molecular Biology Reports. 29: 255-257. PMID 12241067 DOI: 10.1023/A:1020398401293 |
0.304 |
|
| 2002 |
Ortega F, Ehrenberg M, Acerenza L, Westerhoff HV, Mas F, Cascante M. Sensitivity analysis of metabolic cascades catalyzed by bifunctional enzymes. Molecular Biology Reports. 29: 211-5. PMID 12241060 DOI: 10.1023/A:1020334014497 |
0.321 |
|
| 2002 |
Francke C, Westerhoff HV, Blom JG, Peletier MA. Flux control of the bacterial phosphoenolpyruvate:glucose phosphotransferase system and the effect of diffusion Molecular Biology Reports. 29: 21-26. PMID 12241059 DOI: 10.1023/A:1020389915464 |
0.314 |
|
| 2002 |
Westerhoff HV, Getz WM, Bruggeman F, Hofmeyr JH, Rohwer JM, Snoep JL. ECA: control in ecosystems. Molecular Biology Reports. 29: 113-7. PMID 12241039 DOI: 10.1023/A:1020396906319 |
0.323 |
|
| 2002 |
Bakker BM, Assmus HE, Bruggeman F, Haanstra JR, Klipp E, Westerhoff H. Network-Based Selectivity of Antiparasitic Inhibitors Molecular Biology Reports. 29: 1-5. PMID 12241036 DOI: 10.1023/A:1020397513646 |
0.301 |
|
| 2002 |
De La Fuente A, Snoep JL, Westerhoff HV, Mendes P. Metabolic control in integrated biochemical systems European Journal of Biochemistry. 269: 4399-4408. PMID 12230551 DOI: 10.1046/J.1432-1033.2002.03088.X |
0.392 |
|
| 2002 |
Koefoed S, Otten MF, Koebmann BJ, Bruggeman FJ, Bakker BM, Snoep JL, Krab K, Van Spanning RJM, Van Verseveld HW, Jensen PR, Koster JG, Westerhoff HV. A turbo engine with automatic transmission? How to marry chemicomotion to the subtleties and robustness of life Biochimica Et Biophysica Acta - Bioenergetics. 1555: 75-82. PMID 12206895 DOI: 10.1016/S0005-2728(02)00258-X |
0.365 |
|
| 2002 |
Koebmann BJ, Westerhoff HV, Snoep JL, Nilsson D, Jensen PR. The glycolytic flux in Escherichia coli is controlled by the demand for ATP Journal of Bacteriology. 184: 3909-3916. PMID 12081962 DOI: 10.1128/Jb.184.14.3909-3916.2002 |
0.371 |
|
| 2002 |
Hoefnagel MHN, Starrenburg MJC, Martens DE, Hugenholtz J, Kleerebezem M, Van Swam II, Bongers R, Westerhoff HV, Snoep JL. Metabolic engineering of lactic acid bacteria, the combined approach: Kinetic modelling, metabolic control and experimental analysis Microbiology. 148: 1003-1013. PMID 11932446 DOI: 10.1099/00221287-148-4-1003 |
0.365 |
|
| 2002 |
Danø S, Hynne F, Monte SD, d'Ovidio F, Sørensen PG, Westerhoff H. Synchronization of glycolytic oscillations in a yeast cell population. Faraday Discussions. 120: 261-275. PMID 11901680 DOI: 10.1039/B103238K |
0.331 |
|
| 2002 |
Jonker CM, Snoep JL, Treur J, Westerhoff HV, Wijngaards WC. Putting intentions into cell biochemistry: an artificial intelligence perspective. Journal of Theoretical Biology. 214: 105-34. PMID 11786036 DOI: 10.1006/Jtbi.2001.2444 |
0.31 |
|
| 2002 |
Van Rotterdam BJ, Crielaard W, Van Stokkum IHM, Hellingwerf KJ, Westerhoff HV. Simplicity in complexity: The photosynthetic reaction center performs as a simple 0.2 V battery Febs Letters. 510: 105-107. PMID 11755540 DOI: 10.1016/S0014-5793(01)03210-0 |
0.472 |
|
| 2002 |
Reijenga KA, Westerhoff HV, Kholodenko BN, Snoep JL. Control analysis for autonomously oscillating biochemical networks Biophysical Journal. 82: 99-108. PMID 11751299 DOI: 10.1016/S0006-3495(02)75377-0 |
0.337 |
|
| 2001 |
Demin OV, Kholodenko BN, Westerhoff HV. Kinetic modeling of energy metabolism and superoxide generation in hepatocyte mitochondria Molekulyarnaya Biologiya. 35: 1095-1104. PMID 11771135 DOI: 10.1023/A:1013211007465 |
0.323 |
|
| 2001 |
Hoffer SM, Westerhoff HV, Hellingwerf KJ, Postma PW, Tommassen J. Autoamplification of a two-component regulatory system results in "learning" behavior. Journal of Bacteriology. 183: 4914-7. PMID 11466297 DOI: 10.1128/Jb.183.16.4914-4917.2001 |
0.471 |
|
| 2001 |
Kuile BH, Westerhoff HV. Transcriptome meets metabolome: Hierarchical and metabolic regulation of the glycolytic pathway Febs Letters. 500: 169-171. PMID 11445079 DOI: 10.1016/S0014-5793(01)02613-8 |
0.318 |
|
| 2001 |
Hofmeyr JHS, Westerhoff HV. Building the cellular puzzle: Control in multi-level reaction networks Journal of Theoretical Biology. 208: 261-285. PMID 11207090 DOI: 10.1006/Jtbi.2000.2216 |
0.343 |
|
| 2001 |
van Rotterdam BJ, Westerhoff HV, Visschers RW, Bloch DA, Hellingwerf KJ, Jones MR, Crielaard W. Pumping capacity of bacterial reaction centers and backpressure regulation of energy transduction. European Journal of Biochemistry / Febs. 268: 958-70. PMID 11179962 DOI: 10.1046/J.1432-1327.2001.01951.X |
0.505 |
|
| 2001 |
Reijenga KA, Snoep JL, Diderich JA, Van Verseveld HW, Westerhoff HV, Teusink B. Control of glycolytic dynamics by hexose transport in Saccharomyces cerevisiae Biophysical Journal. 80: 626-634. PMID 11159431 DOI: 10.1016/S0006-3495(01)76043-2 |
0.316 |
|
| 2001 |
Raamsdonk LM, Teusink B, Broadhurst D, Zhang N, Hayes A, Walsh MC, Berden JA, Brindle KM, Kell DB, Rowland JJ, Westerhoff HV, van Dam K, Oliver SG. A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nature Biotechnology. 19: 45-50. PMID 11135551 DOI: 10.1038/83496 |
0.54 |
|
| 2000 |
van Rotterdam BJ, Westerhoff HV, Visschers RW, Jones MR, Hellingwerf KJ, Crielaard W. Steady-state cyclic electron transfer through solubilized Rhodobacter sphaeroides reaction centres. Biophysical Chemistry. 88: 137-52. PMID 11152271 DOI: 10.1016/S0301-4622(00)00206-4 |
0.498 |
|
| 2000 |
Somsen OJG, Hoeben MA, Esgalhado E, Snoep JL, Visser D, Van der Heijden RTJM, Heijnen JJ, Westerhoff HV. Glucose and the ATP paradox in yeast Biochemical Journal. 352: 593-599. PMID 11085955 DOI: 10.1042/0264-6021:3520593 |
0.322 |
|
| 2000 |
Bruggeman FJ, Heeswijk WCv, Boogerd FC, Westerhoff HV. Macromolecular intelligence in microorganisms. Biological Chemistry. 381: 965-972. PMID 11076029 DOI: 10.1515/Bc.2000.119 |
0.321 |
|
| 2000 |
Teusink B, Passarge J, Reijenga CA, Esgalhado E, van der Weijden CC, Schepper M, Walsh MC, Bakker BM, van Dam K, Westerhoff HV, Snoep JL. Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry. European Journal of Biochemistry / Febs. 267: 5313-29. PMID 10951190 DOI: 10.1046/J.1432-1327.2000.01527.X |
0.554 |
|
| 2000 |
Jeneson JA, Westerhoff HV, Kushmerick MJ. A metabolic control analysis of kinetic controls in ATP free energy metabolism in contracting skeletal muscle. American Journal of Physiology. Cell Physiology. 279: C813-32. PMID 10942732 DOI: 10.1152/Ajpcell.2000.279.3.C813 |
0.339 |
|
| 2000 |
Kholodenko BN, Westerhoff HV, Schwaber J, Cascante M. Engineering a living cell to desired metabolite concentrations and fluxes: Pathways with multifunctional enzymes Metabolic Engineering. 2: 1-13. PMID 10935931 DOI: 10.1006/Mben.1999.0132 |
0.35 |
|
| 2000 |
Schuster S, Kholodenko BN, Westerhoff HV. Cellular information transfer regarded from a stoichiometry and control analysis perspective Biosystems. 55: 73-81. PMID 10745111 DOI: 10.1016/S0303-2647(99)00085-4 |
0.338 |
|
| 2000 |
Bakker BM, Westerhoff HV, Opperdoes FR, Michels PA. Metabolic control analysis of glycolysis in trypanosomes as an approach to improve selectivity and effectiveness of drugs. Molecular and Biochemical Parasitology. 106: 1-10. PMID 10743606 DOI: 10.1016/S0166-6851(99)00197-8 |
0.339 |
|
| 2000 |
Teusink B, Westerhoff HV. 'Slave' metabolites and enzymes. A rapid way of delineating metabolic control European Journal of Biochemistry. 267: 1889-1893. PMID 10727927 DOI: 10.1046/J.1432-1327.2000.01220.X |
0.358 |
|
| 2000 |
Wolf J, Passarge J, Somsen OJ, Snoep JL, Heinrich R, Westerhoff HV. Transduction of intracellular and intercellular dynamics in yeast glycolytic oscillations. Biophysical Journal. 78: 1145-53. PMID 10692304 DOI: 10.1016/S0006-3495(00)76672-0 |
0.322 |
|
| 2000 |
Bier M, Bakker BM, Westerhoff HV. How yeast cells synchronize their glycolytic oscillations: A perturbation analytic treatment Biophysical Journal. 78: 1087-1093. PMID 10692299 DOI: 10.1016/S0006-3495(00)76667-7 |
0.322 |
|
| 2000 |
Bakker BM, Mensonides FI, Teusink B, van Hoek P, Michels PA, Westerhoff HV. Compartmentation protects trypanosomes from the dangerous design of glycolysis. Proceedings of the National Academy of Sciences of the United States of America. 97: 2087-92. PMID 10681445 DOI: 10.1073/Pnas.030539197 |
0.336 |
|
| 1999 |
Moreno-Sánchez R, Bravo C, Westerhoff HV. Determining and understanding the control of flux. An illustration in submitochondrial particles of how to validate schemes of metabolic control. European Journal of Biochemistry. 264: 427-33. PMID 10491087 DOI: 10.1046/J.1432-1327.1999.00621.X |
0.328 |
|
| 1999 |
Bakker BM, Michels PA, Opperdoes FR, Westerhoff HV. What controls glycolysis in bloodstream form Trypanosoma brucei? The Journal of Biological Chemistry. 274: 14551-9. PMID 10329645 DOI: 10.1074/Jbc.274.21.14551 |
0.33 |
|
| 1999 |
Schuster S, Westerhoff HV. Modular control analysis of slipping enzymes. Bio Systems. 49: 1-15. PMID 10091969 DOI: 10.1016/S0303-2647(98)00028-8 |
0.358 |
|
| 1999 |
Demin OV, Westerhoff HV, Kholodenko BN. Control analysis of stationary forced oscillations. Journal of Physical Chemistry B. 103: 10695-10710. DOI: 10.1021/Jp991597B |
0.339 |
|
| 1998 |
Kholodenko BN, Cascante M, Hoek JB, Westerhoff HV, Schwaber J. Metabolic design: How to engineer a living cell to desired metabolite concentrations and fluxes Biotechnology and Bioengineering. 59: 239-247. PMID 10099334 DOI: 10.1002/(Sici)1097-0290(19980720)59:2<239::Aid-Bit11>3.0.Co;2-9 |
0.353 |
|
| 1998 |
Rohwer JM, Postma PW, Kholodenko BN, Westerhoff HV. Implications of macromolecular crowding for signal transduction and metabolite channeling Proceedings of the National Academy of Sciences of the United States of America. 95: 10547-10552. PMID 9724740 DOI: 10.1073/Pnas.95.18.10547 |
0.343 |
|
| 1998 |
Rohwer JM, Bader R, Westerhoff HV, Postma PW. Limits to inducer exclusion: inhibition of the bacterial phosphotransferase system by glycerol kinase. Molecular Microbiology. 29: 641-52. PMID 9720879 DOI: 10.1046/J.1365-2958.1998.00963.X |
0.317 |
|
| 1998 |
Teusink B, Walsh MC, van Dam K, Westerhoff HV. The danger of metabolic pathways with turbo design. Trends in Biochemical Sciences. 23: 162-9. PMID 9612078 DOI: 10.1016/S0968-0004(98)01205-5 |
0.566 |
|
| 1998 |
Kholodenko BN, Schuster S, Garcia J, Westerhoff HV, Cascante M. Control analysis of metabolic systems involving quasi-equilibrium reactions Biochimica Et Biophysica Acta - General Subjects. 1379: 337-352. PMID 9545597 DOI: 10.1016/S0304-4165(97)00114-1 |
0.319 |
|
| 1998 |
Teusink B, Diderich JA, Westerhoff HV, van Dam K, Walsh MC. Intracellular glucose concentration in derepressed yeast cells consuming glucose is high enough to reduce the glucose transport rate by 50%. Journal of Bacteriology. 180: 556-62. PMID 9457857 DOI: 10.1128/Jb.180.3.556-562.1998 |
0.504 |
|
| 1998 |
van der Gugten AA, Westerhoff HV. Internal regulation of a modular system: the different faces of internal control. Bio Systems. 44: 79-106. PMID 9429746 DOI: 10.1016/S0303-2647(97)00041-5 |
0.335 |
|
| 1998 |
Teusink B, Baganz F, Westerhoff HV, Oliver SG. Metabolic control analysis as a tool in the elucidation of the function of novel genes Methods in Microbiology. 26: 297-336. DOI: 10.1016/S0580-9517(08)70338-6 |
0.349 |
|
| 1998 |
Westerhoff H, Jensen P, Snoep J, Kholodenko B. Thermodynamics of complexity. The live cell Thermochimica Acta. 309: 111-120. DOI: 10.1016/S0040-6031(97)00353-5 |
0.354 |
|
| 1998 |
Kholodenko BN, Rohwer JM, Cascante M, Westerhoff HV. Subtleties in control by metabolic channelling and enzyme organization Molecular and Cellular Biochemistry. 184: 311-320. DOI: 10.1007/978-1-4615-5653-4_20 |
0.379 |
|
| 1997 |
Bakker BM, Michels PA, Opperdoes FR, Westerhoff HV. Glycolysis in bloodstream form Trypanosoma brucei can be understood in terms of the kinetics of the glycolytic enzymes. The Journal of Biological Chemistry. 272: 3207-15. PMID 9013556 DOI: 10.1074/Jbc.272.6.3207 |
0.325 |
|
| 1997 |
Jensen PR, Michelsen O, Westerhoff HV. Experimental determination of control by the H(+)-ATPase in Escherichia coli. Journal of Bioenergetics and Biomembranes. 27: 543-54. PMID 8746842 DOI: 10.1007/Bf02111653 |
0.304 |
|
| 1997 |
Kholodenko BN, Demin OV, Westerhoff HV. Control Analysis of Periodic Phenomena in Biological Systems The Journal of Physical Chemistry B. 101: 2070-2081. DOI: 10.1021/Jp962336U |
0.339 |
|
| 1996 |
Bier M, Teusink B, Kholodenko BN, Westerhoff HV. Control analysis of glycolytic oscillations Biophysical Chemistry. 62: 15-24. PMID 8962468 DOI: 10.1016/S0301-4622(96)02195-3 |
0.319 |
|
| 1996 |
Brown GC, Westerhoff HV, Kholodenko BN. Molecular control analysis: Control within proteins and molecular processes Journal of Theoretical Biology. 182: 389-396. PMID 8944172 DOI: 10.1006/Jtbi.1996.0178 |
0.333 |
|
| 1996 |
Richard P, Teusink B, Hemker MB, Van Dam K, Westerhoff HV. Sustained oscillations in free-energy state and hexose phosphates in yeast. Yeast (Chichester, England). 12: 731-40. PMID 8813760 DOI: 10.1002/(Sici)1097-0061(19960630)12:8<731::Aid-Yea961>3.0.Co;2-Z |
0.561 |
|
| 1996 |
Teusink B, Larsson C, Diderich J, Richard P, van Dam K, Gustafsson L, Westerhoff HV. Synchronized heat flux oscillations in yeast cell populations. The Journal of Biological Chemistry. 271: 24442-8. PMID 8798702 DOI: 10.1074/Jbc.271.40.24442 |
0.52 |
|
| 1996 |
Kholodenko BN, Sakamoto N, Puigjaner J, Westerhoff HV, Cascante M. Strong control on the transit time in metabolic channelling Febs Letters. 389: 123-125. PMID 8766813 DOI: 10.1016/0014-5793(96)00532-7 |
0.301 |
|
| 1996 |
Rohwer JM, Schuster S, Westerhoff HV. How to recognize monofunctional units in a metabolic system. Journal of Theoretical Biology. 179: 213-28. PMID 8762334 DOI: 10.1006/Jtbi.1996.0062 |
0.325 |
|
| 1996 |
Bakker BM, Westerhoff HV, Michels PA. Regulation and control of compartmentalized glycolysis in bloodstream form Trypanosoma brucei. Journal of Bioenergetics and Biomembranes. 27: 513-25. PMID 8718456 DOI: 10.1007/Bf02110191 |
0.379 |
|
| 1996 |
Teusink B, Bakker BM, Westerhoff HV. Control of frequency and amplitudes is shared by all enzymes in three models for yeast glycolytic oscillations. Biochimica Et Biophysica Acta. 1275: 204-12. PMID 8695635 DOI: 10.1016/0005-2728(96)00026-6 |
0.332 |
|
| 1996 |
Richard P, Bakker BM, Teusink B, Van Dam K, Westerhoff HV. Acetaldehyde mediates the synchronization of sustained glycolytic oscillations in populations of yeast cells. European Journal of Biochemistry / Febs. 235: 238-41. PMID 8631335 DOI: 10.1111/J.1432-1033.1996.00238.X |
0.513 |
|
| 1996 |
Rohwer JM, Jensen PR, Shinohara Y, Postma PW, Westerhoff HV. Changes in the cellular energy state affect the activity of the bacterial phosphotransferase system. European Journal of Biochemistry. 235: 225-30. PMID 8631333 DOI: 10.1111/J.1432-1033.1996.00225.X |
0.331 |
|
| 1996 |
Kholodenko BN, Westerhoff HV, Cascante M. Effect of channelling on the concentration of bulk-phase intermediates as cytosolic proteins become more concentrated Biochemical Journal. 313: 921-926. PMID 8611176 DOI: 10.1042/Bj3130921 |
0.325 |
|
| 1996 |
Mendes P, Kell DB, Westerhoff HV. Why and when channelling can decrease pool size at constant net flux in a simple dynamic channel. Biochimica Et Biophysica Acta. 1289: 175-86. PMID 8600971 DOI: 10.1016/0304-4165(95)00152-2 |
0.31 |
|
| 1995 |
Van Spanning RJ, de Boer AP, Reijnders WN, De Gier JW, Delorme CO, Stouthamer AH, Westerhoff HV, Harms N, van der Oost J. Regulation of oxidative phosphorylation: the flexible respiratory network of Paracoccus denitrificans. Journal of Bioenergetics and Biomembranes. 27: 499-512. PMID 8718455 DOI: 10.1007/Bf02110190 |
0.322 |
|
| 1995 |
Westerhoff HV, Kholodenko BN, Cascante M, Van Dam K. Elusive control. Journal of Bioenergetics and Biomembranes. 27: 491-7. PMID 8718454 DOI: 10.1007/BF02110189 |
0.503 |
|
| 1995 |
Kholodenko BN, Cascante M, Westerhoff HV. Control theory of metabolic channelling. Molecular and Cellular Biochemistry. 313-31. PMID 7808462 DOI: 10.1007/Bf01267963 |
0.349 |
|
| 1995 |
Jensen PR, Loman L, Petra B, van der Weijden C, Westerhoff HV. Energy buffering of DNA structure fails when Escherichia coli runs out of substrate. Journal of Bacteriology. 177: 3420-6. PMID 7768851 DOI: 10.1128/Jb.177.12.3420-3426.1995 |
0.317 |
|
| 1995 |
Kholodenko BN, Westerhoff HV. The macroworld versus the microworld of biochemical regulation and control Trends in Biochemical Sciences. 20: 52-54. PMID 7701560 DOI: 10.1016/S0968-0004(00)88955-0 |
0.346 |
|
| 1995 |
Hellingwerf KJ, Postma PW, Tommassen J, Westerhoff HV. Signal transduction in bacteria: phospho-neural network(s) in Escherichia coli? Fems Microbiology Reviews. 16: 309-21. PMID 7654406 DOI: 10.1111/J.1574-6976.1995.Tb00178.X |
0.499 |
|
| 1995 |
Kholodenko BN, Schuster S, Rohwer JM, Cascante M, Westerhoff HV. Composite control of cell function: metabolic pathways behaving as single control units Febs Letters. 368: 1-4. PMID 7615057 DOI: 10.1016/0014-5793(95)00562-N |
0.372 |
|
| 1995 |
SCHUSTER S, KAHN D, WESTERHOFF HV. CONTROL ANALYSIS OF METABOLIC SYSTEMS CONSISTING OF UNI- AND/OR MULTIFUNCTIONAL UNITS: APPLICATION TO MODULAR SYSTEMS AND SLIPPING ENZYMES Journal of Biological Systems. 3: 217-230. DOI: 10.1142/S0218339095000216 |
0.365 |
|
| 1995 |
MOLENAAR D, KHOLODENKO BN, VAN HEESWIJK WC, WESTERHOFF HV. DYNAMIC ASPECTS OF CASCADE-TYPE METABOLIC REGULATION Journal of Biological Systems. 3: 187-196. DOI: 10.1142/S0218339095000186 |
0.323 |
|
| 1995 |
KHOLODENKO B, CASCANTE M, MOLENAAR D, DEMIN O, VAN DER GUGTEN A, WESTERHOFF H. CONTROL THEORY OF CELL METABOLISM: TOWARDS MORE REALISTIC “NON-IDEAL” SYSTEMS Journal of Biological Systems. 3: 145-154. DOI: 10.1142/S0218339095000149 |
0.367 |
|
| 1995 |
JENSEN P, VAN DER GUGTEN A, BIER M, VAN HEESWIJK W, ROHWER J, MOLENAAR D, VAN WORKUM M, RICHARD P, TEUSINK B, BAKKER B, KHOLODENKO B, WESTERHOFF H. HIERARCHIES IN CONTROL Journal of Biological Systems. 3: 139-144. DOI: 10.1142/S0218339095000137 |
0.339 |
|
| 1995 |
Snoep JL, Yomano LP, Westerhoff HV, Ingram LO. Protein burden in Zymomonas mobilis: negative flux and growth control due to overproduction of glycolytic enzymes Microbiology. 141: 2329-2337. DOI: 10.1099/13500872-141-9-2329 |
0.338 |
|
| 1995 |
Westerhoff HV. Henrik Kacser (1918–1995): metabolism of control Trends in Biotechnology. 13: 245. DOI: 10.1016/S0167-7799(00)88956-8 |
0.306 |
|
| 1995 |
Kholodenko BN, Molenaar D, Schuster S, Heinrich R, Westerhoff HV. Defining control coefficients in non-ideal metabolic pathways Biophysical Chemistry. 56: 215-226. DOI: 10.1016/0301-4622(95)00039-Z |
0.362 |
|
| 1995 |
Kholodenko BN, Westerhoff HV, Puigjaner J, Cascante M. Control in channelled pathways. A matrix method calculating the enzyme control coefficients Biophysical Chemistry. 53: 247-258. DOI: 10.1016/0301-4622(94)00104-R |
0.35 |
|
| 1995 |
Kholodenko BN, Westerhoff HV. Control theory of group transfer pathways Bba - Bioenergetics. 1229: 256-274. DOI: 10.1016/0005-2728(95)00014-A |
0.356 |
|
| 1995 |
Kholodenko BN, Westerhoff HV. How to reveal various aspects of regulation in group-transfer pathways Bba - Bioenergetics. 1229: 275-289. DOI: 10.1016/0005-2728(95)00013-9 |
0.349 |
|
| 1994 |
Westerhoff HV, Kahn D. Control involving metabolism and gene expression: the square-matrix method for modular decomposition. Acta Biotheoretica. 41: 75-83. PMID 8266747 DOI: 10.1007/Bf00712776 |
0.327 |
|
| 1994 |
Schuster S, Kahn D, Westerhoff HV. Modular analysis of the control of complex metabolic pathways. Biophysical Chemistry. 48: 1-17. PMID 8257764 DOI: 10.1016/0301-4622(93)80037-J |
0.345 |
|
| 1994 |
Richard P, Diderich JA, Bakker BM, Teusink B, van Dam K, Westerhoff HV. Yeast cells with a specific cellular make-up and an environment that removes acetaldehyde are prone to sustained glycolytic oscillations. Febs Letters. 341: 223-6. PMID 8137943 DOI: 10.1016/0014-5793(94)80461-3 |
0.543 |
|
| 1994 |
Kholodenko BN, Westerhoff HV, Brown GC. Rate limitation within a single enzyme is directly related to enzyme intermediate levels Febs Letters. 349: 131-134. PMID 8045290 DOI: 10.1016/0014-5793(94)00617-2 |
0.312 |
|
| 1994 |
Westerhoff HV, Hofmeyr JHS, Kholodenko BN. Getting to the inside of cells using metabolic control analysis Biophysical Chemistry. 50: 273-283. PMID 8011948 DOI: 10.1016/0301-4622(93)E0095-M |
0.357 |
|
| 1994 |
Kholodenko BN, Westerhoff HV. Control theory of one enzyme Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 1208: 294-305. PMID 7947961 DOI: 10.1016/0167-4838(94)90116-3 |
0.346 |
|
| 1994 |
Kholodenko BN, Sauro HM, Westerhoff HV. Control by enzymes, coenzymes and conserved moieties. A generalisation of the connectivity theorem of metabolic control analysis. European Journal of Biochemistry / Febs. 225: 179-86. PMID 7925436 DOI: 10.1111/J.1432-1033.1994.00179.X |
0.358 |
|
| 1993 |
Vosman B, Rauch PJ, Westerhoff HV, Hellingwerf KJ. Regulation of the expression of the Pseudomonas stutzeri recA gene. Antonie Van Leeuwenhoek. 63: 55-62. PMID 8480993 DOI: 10.1007/Bf00871732 |
0.467 |
|
| 1993 |
van Dam K, van der Vlag J, Kholodenko BN, Westerhoff HV. The sum of the control coefficients of all enzymes on the flux through a group-transfer pathway can be as high as two. European Journal of Biochemistry / Febs. 212: 791-9. PMID 8462550 DOI: 10.1111/J.1432-1033.1993.Tb17720.X |
0.564 |
|
| 1993 |
Richard P, Teusink B, Westerhoff HV, van Dam K. Around the growth phase transition S. cerevisiae's make-up favours sustained oscillations of intracellular metabolites. Febs Letters. 318: 80-2. PMID 8436231 DOI: 10.1016/0014-5793(93)81332-T |
0.55 |
|
| 1993 |
Jensen PR, Westerhoff HV, Michelsen O. The use of lac-type promoters in control analysis. European Journal of Biochemistry. 211: 181-91. PMID 8425528 DOI: 10.1111/J.1432-1033.1993.Tb19885.X |
0.315 |
|
| 1993 |
Jensen PR, Michelsen O, Westerhoff HV. Control analysis of the dependence of Escherichia coli physiology on the H(+)-ATPase. Proceedings of the National Academy of Sciences of the United States of America. 90: 8068-72. PMID 8367465 DOI: 10.1073/Pnas.90.17.8068 |
0.338 |
|
| 1993 |
Kholodenko BN, Cascante M, Westerhoff HV. Dramatic changes in control properties that accompany channelling and metabolite sequestration Febs Letters. 336: 381-384. PMID 8282097 DOI: 10.1016/0014-5793(93)80841-H |
0.348 |
|
| 1993 |
Hendler RW, Westerhoff HV. Redox interactions in cytochrome c oxidase: from the "neoclassical" toward "modern" models. Biophysical Journal. 63: 1586-604. PMID 1336989 DOI: 10.1016/S0006-3495(92)81748-4 |
0.301 |
|
| 1993 |
Jensen P, Westerhoff H, Michelsen O. Excess capacity of H(+)-ATPase and inverse respiratory control in Escherichia coli. The Embo Journal. 12: 1277-1282. DOI: 10.1002/J.1460-2075.1993.Tb05772.X |
0.315 |
|
| 1992 |
Westerhoff HV, van Heeswijk W, Kahn D, Kell DB. Quantitative approaches to the analysis of the control and regulation of microbial metabolism. Antonie Van Leeuwenhoek. 60: 193-207. PMID 1687235 DOI: 10.1007/978-94-011-2446-1_6 |
0.336 |
|
| 1992 |
Westerhoff HV, Welch GR. Enzyme organization and the direction of metabolic flow: physicochemical considerations Current Topics in Cellular Regulation. 33: 361-390. PMID 1499341 DOI: 10.1016/B978-0-12-152833-1.50026-5 |
0.357 |
|
| 1992 |
Westerhoff HV, van Dam K. Chapter 1 Thermodynamics and the regulation of cell functions New Comprehensive Biochemistry. 23: 1-35. DOI: 10.1016/S0167-7306(08)60169-6 |
0.571 |
|
| 1991 |
Aon MA, Cortassa S, Westerhoff HV, Berden JA, Van Spronsen E, Van Dam K. Dynamic regulation of yeast glycolytic oscillations by mitochondrial functions. Journal of Cell Science. 99: 325-34. PMID 1885673 |
0.492 |
|
| 1991 |
Rutgers M, Dam KV, Westerhoff HV. Control and Thermodynamics of Microbial Growth: Rational Tools for Bioengineering Critical Reviews in Biotechnology. 11: 367-395. DOI: 10.3109/07388559109040625 |
0.361 |
|
| 1990 |
Westerhoff HV, Aon MA, van Dam K, Cortassa S, Kahn D, van Workum M. Dynamical and hierarchical coupling Bba - Bioenergetics. 1018: 142-146. DOI: 10.1016/0005-2728(90)90235-V |
0.475 |
|
| 1989 |
Westerhoff HV, Wiechmann AH, van Dam K, Hellingwerf KJ. On the evaluation of data from flow-dialysis experiments. Journal of Biochemical and Biophysical Methods. 18: 53-64. PMID 2723331 DOI: 10.1016/0165-022X(89)90013-4 |
0.599 |
|
| 1989 |
Westerhoff HV. Control, regulation and thermodynamics of free-energy transduction Biochimie. 71: 877-886. PMID 2508760 DOI: 10.1016/0300-9084(89)90071-0 |
0.381 |
|
| 1988 |
Kamp F, Astumian RD, Westerhoff HV. Coupling of vectorial proton flow to a biochemical reaction by local electric interactions. Proceedings of the National Academy of Sciences of the United States of America. 85: 3792-6. PMID 2836858 DOI: 10.1073/Pnas.85.11.3792 |
0.302 |
|
| 1987 |
Westerhoff HV, Plomp PJ, Groen AK, Wanders RJ, Bode JA, van Dam K. On the origin of the limited control of mitochondrial respiration by the adenine nucleotide translocator. Archives of Biochemistry and Biophysics. 257: 154-69. PMID 2888431 DOI: 10.1016/0003-9861(87)90554-6 |
0.537 |
|
| 1986 |
Westerhoff HV, Van der Bend RL, Van Dam K, Berden J, Peterson J. A model system for delocalized chemiosmotic coupling exhibited the features thought diagnostic of localized coupling. The Biochemical Journal. 236: 932-3. PMID 2947574 DOI: 10.1042/Bj2360932 |
0.479 |
|
| 1986 |
Westerhoff HV, Tsong TY, Chock PB, Chen YD, Astumian RD. How enzymes can capture and transmit free energy from an oscillating electric field. Proceedings of the National Academy of Sciences of the United States of America. 83: 4734-8. PMID 2941758 DOI: 10.1073/Pnas.83.13.4734 |
0.309 |
|
| 1986 |
Kell DB, Westerhoff HV. Metabolic control theory: its role in microbiology and biotechnology Fems Microbiology Letters. 39: 305-320. DOI: 10.1111/J.1574-6968.1986.Tb01863.X |
0.304 |
|
| 1986 |
Chen Y, Westerhoff HV. How do inhibitors and modifiers of individual enzymes affect steady-state fluxes and concentrations in metabolic systems? Mathematical Modelling. 7: 1173-1180. DOI: 10.1016/0270-0255(86)90073-4 |
0.351 |
|
| 1985 |
Westerhoff HV, Chen Y. Stochastic free energy transduction. Proceedings of the National Academy of Sciences of the United States of America. 82: 3222-6. PMID 3858819 DOI: 10.1073/Pnas.82.10.3222 |
0.314 |
|
| 1985 |
Van der Bend RL, Petersen J, Berden JA, Van Dam K, Westerhoff HV. A critical appraisal of evidence for localized energy coupling. Kinetic studies on liposomes containing bacteriorhodopsin and ATP synthase. The Biochemical Journal. 230: 543-9. PMID 2996506 DOI: 10.1042/Bj2300543 |
0.538 |
|
| 1985 |
Burns JA, Cornish-Bowden A, Groen AK, Heinrich R, Kacser H, Porteous JW, Rapoport SM, Rapoport TA, Stucki JW, Tager JM, Wanders RJA, Westerhoff HV. Control analysis of metabolic systems Trends in Biochemical Sciences. 10: 16. DOI: 10.1016/0968-0004(85)90008-8 |
0.319 |
|
| 1984 |
Westerhoff HV, Chen YD. How do enzyme activities control metabolite concentrations? An additional theorem in the theory of metabolic control. European Journal of Biochemistry. 142: 425-30. PMID 6745283 DOI: 10.1111/J.1432-1033.1984.Tb08304.X |
0.351 |
|
| 1984 |
Kohen E, Kohen C, Hirschberg JG, Wouters AW, Thorell B, Westerhoff HV, Charyulu KK. Metabolic control and compartmentation in single living cells. Cell Biochemistry and Function. 1: 3-16. PMID 6678615 DOI: 10.1002/Cbf.290010103 |
0.338 |
|
| 1984 |
Westerhoff HV, Groen AK, Wanders RJ. Modern theories of metabolic control and their applications (review). Bioscience Reports. 4: 1-22. PMID 6365197 DOI: 10.1007/Bf01120819 |
0.362 |
|
| 1984 |
Van Dam K, Woelders H, Colen A, Westerhoff HV. A structural basis for mosaic protonic energy coupling. Biochemical Society Transactions. 12: 401-2. PMID 6329842 DOI: 10.1042/Bst0120401 |
0.499 |
|
| 1984 |
Westerhoff HV, Arents JC. Two (completely) rate-limiting steps in one metabolic pathway? The resolution of a paradox using bacteriorhodopsin liposomes and the control theory. Bioscience Reports. 4: 23-31. PMID 6320924 DOI: 10.1007/Bf01120820 |
0.311 |
|
| 1984 |
Van Dam K, Westerhoff HV. Chapter 1 Thermodynamic aspects of bioenergetics New Comprehensive Biochemistry. 9: 1-27. DOI: 10.1016/S0167-7306(08)60311-7 |
0.535 |
|
| 1984 |
WESTERHOFF H, DANCSHAZY Z. Keeping a light-driven proton pump under control Trends in Biochemical Sciences. 9: 112-117. DOI: 10.1016/0968-0004(84)90107-5 |
0.325 |
|
| 1983 |
Westerhoff HV, Hellingwerf KJ, Van Dam K. Thermodynamic efficiency of microbial growth is low but optimal for maximal growth rate. Proceedings of the National Academy of Sciences of the United States of America. 80: 305-9. PMID 6572006 DOI: 10.1073/Pnas.80.1.305 |
0.605 |
|
| 1983 |
Westerhoff HV, Colen AM, van Dam K. Metabolic control by pump slippage and proton leakage in 'delocalized' and more localized chemiosmotic energy-coupling schemes. Biochemical Society Transactions. 11: 81-5. PMID 6298029 DOI: 10.1042/Bst0110081 |
0.531 |
|
| 1982 |
Westerhoff HV, Lolkema JS, Otto R, Hellingwerf KJ. Thermodynamics of growth. Non-equilibrium thermodynamics of bacterial growth. The phenomenological and the mosaic approach. Biochimica Et Biophysica Acta. 683: 181-220. PMID 7159578 DOI: 10.1016/0304-4173(82)90001-5 |
0.496 |
|
| 1982 |
Arents JC, van Dekken H, Hellingwerf KJ, Westerhoff HV. Linear relations between proton current and pH gradient in bacteriorhodopsin liposomes. Biochemistry. 20: 5114-23. PMID 6271177 DOI: 10.1021/Bi00521A004 |
0.486 |
|
| 1982 |
Hellingwerf KJ, Lolkema JS, Otto R, Neijssel OM, Stouthamer AH, Harder W, van Dam K, Westerhoff HV. Energetics of microbial growth: an analysis of the relationship between growth and its mechanistic basis by mosaic non-equilibrium thermodynamics Fems Microbiology Letters. 15: 7-17. DOI: 10.1111/J.1574-6968.1982.Tb00028.X |
0.488 |
|
| 1981 |
Westerhoff HV, Simonetti AL, Van Dam K. The hypothesis of localized chemiosmosis is unsatisfactory. The Biochemical Journal. 200: 193-202. PMID 6280679 DOI: 10.1042/Bj2000193 |
0.512 |
|
| 1981 |
Westerhoff HV, Hellingwerf KJ, Arents JC, Scholte BJ, Van Dam K. Mosaic nonequilibrium thermodynamics describes biological energy transduction. Proceedings of the National Academy of Sciences of the United States of America. 78: 3554-8. PMID 6267598 DOI: 10.1073/Pnas.78.6.3554 |
0.635 |
|
| 1981 |
Heinz E, Westerhoff HV, van Dam K. The residual protonmotive force in mitochondria after an oxygen pulse. European Journal of Biochemistry / Febs. 115: 107-13. PMID 6262076 DOI: 10.1111/J.1432-1033.1981.Tb06204.X |
0.494 |
|
| 1981 |
Westerhoff H, Arents J, Hellingwerf K. The effect of ionophores and light intensity on the initial rate of proton uptake into bacteriorhodopsin liposomes can be quantitatively described by mosaic non-equilibrium thermodynamics Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 637: 69-79. DOI: 10.1016/0005-2728(81)90211-5 |
0.485 |
|
| 1981 |
Arents JC, Hellingwerf KJ, van Dam K, Westerhoff HV. Bacteriorhodopsin in liposomes: Quantitative evaluation of ΔpH changes induced by variations of light intensity and conductivity parameters The Journal of Membrane Biology. 60: 95-104. DOI: 10.1007/Bf01870413 |
0.48 |
|
| 1980 |
Kohen E, Kohen C, Hirschberg JG, Wouters AW, Westerhoff HV, Bartick PR, Schachtschabel DO, Rabinovitch A, Meda P, Mintz D, Thorell B. Multichannel analysis of intracellular control and intercellular transfer of molecules. International Journal of Bio-Medical Computing. 11: 305-28. PMID 7399736 DOI: 10.1016/0020-7101(80)90035-5 |
0.332 |
|
| 1980 |
Van Dam K, Westerhoff HV, Krab K, van der Meer R, Arents JC. Relationship between chemiosomotic flows and thermodynamic forces in oxidative phosphorylation. Biochimica Et Biophysica Acta. 591: 240-50. PMID 7397123 DOI: 10.1016/0005-2728(80)90156-5 |
0.493 |
|
| 1979 |
Hellingwerf KJ, Arents JC, Scholte BJ, Westerhoff HV. Bacteriorhodopsin in liposomes. II. Experimental evidence in support of a theoretical model. Biochimica Et Biophysica Acta. 547: 561-82. PMID 486434 DOI: 10.1016/0005-2728(79)90034-3 |
0.489 |
|
| 1979 |
Westerhoff HV, Scholte BJ, Hellingwerf KJ. Bacteriorhodopsin in liposomes. I. A description using irreversible thermodynamics. Biochimica Et Biophysica Acta. 547: 544-60. PMID 486433 DOI: 10.1016/0005-2728(79)90033-1 |
0.483 |
|
| 1978 |
Hellingwerf KJ, Schuurmans JJ, Westerhoff HV. Demonstration of coupling between the protonmotive force across bacteriorhodopsin and the flow through its photochemical cycle. Febs Letters. 92: 181-6. PMID 29778 DOI: 10.1016/0014-5793(78)80749-2 |
0.459 |
|
| 1977 |
Van Dam K, Wiechmann AH, Westerhoff HV, Hellingwerf KJ. Proton gradients across energy-transducing membranes. Biochemical Society Transactions. 5: 28-9. PMID 19321 DOI: 10.1042/Bst0050028 |
0.603 |
|
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