Yuval Dor, Ph.D. - Publications

Affiliations: 
Hebrew University, Jerusalem, Jerusalem, Israel 

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Drawshy Z, Neiman D, Fridlich O, Peretz A, Magenheim J, Rozo AV, Doliba NM, Stoffers DA, Kaestner KH, Schatz DA, Wasserfall C, Campbell-Thompson M, Shapiro J, Kaplan T, Shemer R, ... ... Dor Y, et al. DNA methylation-based assessment of cell composition in human pancreas and islets. Diabetes. PMID 38266068 DOI: 10.2337/db23-0704  0.436
2023 Stolovich-Rain M, Fridlich O, Azulai S, Klochendler A, Anzi S, Magenheim J, Stein I, Mushasha F, Glaser B, Pikarsky E, Ben-Zvi D, Dor Y. Extensive elimination of acinar cells during normal postnatal pancreas growth. Cell Reports. 42: 113457. PMID 37995187 DOI: 10.1016/j.celrep.2023.113457  0.679
2023 Cha J, Tong X, Walker EM, Dahan T, Cochrane VA, Ashe S, Russell R, Osipovich AB, Mawla AM, Guo M, Liu JH, Loyd ZA, Huising MO, Magnuson MA, Hebrok M, ... Dor Y, et al. Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity. Jci Insight. 8. PMID 37606041 DOI: 10.1172/jci.insight.166386  0.635
2023 Magenheim J, Maestro MA, Sharon N, Herrera PL, Murtaugh LC, Kopp J, Sander M, Gu G, Melton DA, Ferrer J, Dor Y. Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors. Cell Stem Cell. 30: 488-497.e3. PMID 37028408 DOI: 10.1016/j.stem.2023.03.003  0.617
2022 Furth-Lavi J, Hija A, Tornovsky-Babeay S, Mazouz A, Dahan T, Stolovich-Rain M, Klochendler A, Dor Y, Avrahami D, Glaser B. Glycemic control releases regenerative potential of pancreatic beta cells blocked by severe hyperglycemia. Cell Reports. 41: 111719. PMID 36450253 DOI: 10.1016/j.celrep.2022.111719  0.418
2021 Kaestner KH, Campbell-Thompson M, Dor Y, Gill RG, Glaser B, Kim SK, Sander M, Stabler C, Stewart AF, Powers AC. What is a β cell? - Chapter I in the Human Islet Research Network (HIRN) Review Series. Molecular Metabolism. 101323. PMID 34416394 DOI: 10.1016/j.molmet.2021.101323  0.378
2021 Tornovsky-Babeay S, Weinberg-Corem N, Ben-Haroush Schyr R, Avrahami D, Lavi J, Feleke E, Kaestner KH, Dor Y, Glaser B. Biphasic dynamics of beta cell mass in a mouse model of congenital hyperinsulinism: implications for type 2 diabetes. Diabetologia. PMID 33558985 DOI: 10.1007/s00125-021-05390-x  0.36
2020 Petrenko V, Stolovich-Rain M, Vandereycken B, Giovannoni L, Storch KF, Dor Y, Chera S, Dibner C. The core clock transcription factor BMAL1 drives circadian β-cell proliferation during compensatory regeneration of the endocrine pancreas. Genes & Development. PMID 33184223 DOI: 10.1101/gad.343137.120  0.336
2020 Neiman D, Gillis D, Piyanzin S, Cohen D, Fridlich O, Moss J, Zick A, Oron T, Sundberg F, Forsander G, Skog O, Korsgren O, Levy-Khademi F, Arbell D, Hashavya S, ... ... Dor Y, et al. Multiplexing DNA methylation markers to detect circulating cell-free DNA derived from human pancreatic beta-cells. Jci Insight. PMID 32573495 DOI: 10.1172/Jci.Insight.136579  0.45
2020 Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, et al. Retraction Note: Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Nature Biotechnology. PMID 32066957 DOI: 10.1038/S41587-020-0426-2  0.462
2020 Speake C, Ylescupidez A, Neiman D, Shemer R, Glaser B, Tersey SA, Usmani-Brown S, Clark P, Wilhelm JJ, Bellin MD, Herold KC, Mirmira RG, Dor Y, Evans-Molina C. Circulating unmethylated insulin DNA as a biomarker of human beta cell death: a multi-laboratory assay comparison. The Journal of Clinical Endocrinology and Metabolism. PMID 31913467 DOI: 10.1210/Clinem/Dgaa008  0.447
2020 Petrenko V, Stolovich-Rain M, Vandereycken B, Chera S, Dor Y, Dibner C. 1-LB: Diurnal Regulation of Pancreatic Beta-Cell Proliferation following Massive Ablation Diabetes. 69. DOI: 10.2337/Db20-1-Lb  0.466
2019 Jaafar R, Tran S, Shah A, Sun G, Valdearcos M, Marchetti P, Masini M, Swisa A, Giacometti S, Bernal-Mizrachi E, Matveyenko A, Hebrok M, Dor Y, Rutter GA, Koliwad SK, et al. mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes. The Journal of Clinical Investigation. 130. PMID 31265435 DOI: 10.1172/Jci127021  0.657
2019 Borghesan M, Fafián-Labora J, Eleftheriadou O, Carpintero-Fernández P, Paez-Ribes M, Vizcay-Barrena G, Swisa A, Kolodkin-Gal D, Ximénez-Embún P, Lowe R, Martín-Martín B, Peinado H, Muñoz J, Fleck RA, Dor Y, et al. Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3. Cell Reports. 27: 3956-3971.e6. PMID 31242426 DOI: 10.1016/J.Celrep.2019.05.095  0.426
2019 Mandelbaum AD, Kredo-Russo S, Aronowitz D, Myers N, Yanowski E, Klochendler A, Swisa A, Dor Y, Hornstein E. miR-17-92 and miR-106b-25 clusters regulate beta cell mitotic checkpoint and insulin secretion in mice. Diabetologia. PMID 31187215 DOI: 10.1007/S00125-019-4916-Z  0.422
2018 Moss J, Magenheim J, Neiman D, Zemmour H, Loyfer N, Korach A, Samet Y, Maoz M, Druid H, Arner P, Fu KY, Kiss E, Spalding KL, Landesberg G, Zick A, ... ... Dor Y, et al. Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease. Nature Communications. 9: 5068. PMID 30498206 DOI: 10.1038/S41467-018-07466-6  0.393
2018 Riahi Y, Israeli T, Yeroslaviz R, Chimenez S, Avrahami D, Stolovich-Rain M, Alter I, Sebag M, Polin N, Bernal-Mizrachi E, Dor Y, Cerasi E, Leibowitz G. Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the mouse. Elife. 7. PMID 30412050 DOI: 10.7554/Elife.38472  0.426
2018 Sakikubo M, Furuyama K, Horiguchi M, Hosokawa S, Aoyama Y, Tsuboi K, Goto T, Hirata K, Masui T, Dor Y, Fujiyama T, Hoshino M, Uemoto S, Kawaguchi Y. Ptf1a inactivation in adult pancreatic acinar cells causes apoptosis through activation of the endoplasmic reticulum stress pathway. Scientific Reports. 8: 15812. PMID 30361559 DOI: 10.1038/S41598-018-34093-4  0.381
2018 Horwitz E, Krogvold L, Zhitomirsky S, Swisa A, Fischman M, Lax T, Dahan T, Hurvitz N, Weinberg-Corem N, Klochendler A, Powers AC, Brissova M, Jörns A, Lenzen S, Glaser B, ... ... Dor Y, et al. Beta Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes. Diabetes. PMID 30150306 DOI: 10.2337/Db17-1006  0.492
2018 Anzi S, Stolovich-Rain M, Klochendler A, Fridlich O, Helman A, Paz-Sonnenfeld A, Avni-Magen N, Kaufman E, Ginzberg MB, Snider D, Ray S, Brecht M, Holmes MM, Meir K, Avivi A, ... ... Dor Y, et al. Postnatal Exocrine Pancreas Growth by Cellular Hypertrophy Correlates with a Shorter Lifespan in Mammals. Developmental Cell. 45: 726-737.e3. PMID 29920277 DOI: 10.1016/J.Devcel.2018.05.024  0.418
2018 Gazala SA, Horwitz E, Ben-Haroush Schyr R, Bardugo A, Israeli H, Hija A, Schug J, Shin S, Dor Y, Kaestner KH, Ben-Zvi D. Sleeve Gastrectomy Improves Glycemia Independent of Weight Loss by Restoring Hepatic Insulin Sensitivity. Diabetes. PMID 29475831 DOI: 10.2337/Db17-1028  0.617
2018 Gala-Lopez BL, Neiman D, Kin T, O'Gorman D, Pepper AR, Malcolm AJ, Pianzin S, Senior PA, Campbell P, Glaser B, Dor Y, Shemer R, Shapiro AMJ. Beta Cell Death by Cell-Free DNA and Outcome after Clinical Islet Transplantation. Transplantation. PMID 29329189 DOI: 10.1097/Tp.0000000000002083  0.448
2018 Riahi Y, Israeli T, Yeroslaviz R, Chimenez S, Avrahami D, Stolovich-Rain M, Alter I, Sebag M, Polin N, Bernal-Mizrachi E, Dor Y, Cerasi E, Leibowitz G. Author response: Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the Akita mouse Elife. DOI: 10.7554/Elife.38472.033  0.362
2017 Swisa A, Kaestner KH, Dor Y. Transcriptional Noise and Somatic Mutations in the Aging Pancreas. Cell Metabolism. 26: 809-811. PMID 29211979 DOI: 10.1016/J.Cmet.2017.11.009  0.429
2017 Neiman D, Moss J, Hecht M, Magenheim J, Piyanzin S, Shapiro AMJ, de Koning EJP, Razin A, Cedar H, Shemer R, Dor Y. Islet cells share promoter hypomethylation independently of expression, but exhibit cell-type-specific methylation in enhancers. Proceedings of the National Academy of Sciences of the United States of America. 114: 13525-13530. PMID 29203669 DOI: 10.1073/Pnas.1713736114  0.465
2017 Jäkel C, Bergmann F, Toth R, Assenov Y, van der Duin D, Strobel O, Hank T, Klöppel G, Dorrell C, Grompe M, Moss J, Dor Y, Schirmacher P, Plass C, Popanda O, et al. Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability. Nature Communications. 8: 1323. PMID 29109526 DOI: 10.1038/S41467-017-01118-X  0.313
2017 Avrahami D, Wang YJ, Klochendler A, Dor Y, Glaser B, Kaestner KH. β-Cells are not uniform after all-Novel insights into molecular heterogeneity of insulin-secreting cells. Diabetes, Obesity & Metabolism. 19: 147-152. PMID 28880481 DOI: 10.1111/Dom.13019  0.47
2017 Avrahami D, Klochendler A, Dor Y, Glaser B. Beta cell heterogeneity: an evolving concept. Diabetologia. PMID 28597073 DOI: 10.1007/S00125-017-4326-Z  0.481
2017 Staels W, Heremans Y, Leuckx G, Van Gassen N, Salinno C, De Groef S, Cools M, Keshet E, Dor Y, Heimberg H, De Leu N. Conditional islet hypovascularisation does not preclude beta cell expansion during pregnancy in mice. Diabetologia. PMID 28299380 DOI: 10.1007/S00125-017-4243-1  0.429
2017 Swisa A, Glaser B, Dor Y. Metabolic Stress and Compromised Identity of Pancreatic Beta Cells. Frontiers in Genetics. 8: 21. PMID 28270834 DOI: 10.3389/Fgene.2017.00021  0.481
2017 Helman A, Avrahami D, Klochendler A, Glaser B, Kaestner KH, Ben-Porath I, Dor Y. Effects of ageing and senescence on pancreatic β-cell function. Diabetes, Obesity & Metabolism. 58-62. PMID 27615132 DOI: 10.1111/Dom.12719  0.448
2016 Swisa A, Avrahami D, Eden N, Zhang J, Feleke E, Dahan T, Cohen-Tayar Y, Stolovich-Rain M, Kaestner KH, Glaser B, Ashery-Padan R, Dor Y. PAX6 maintains β cell identity by repressing genes of alternative islet cell types. The Journal of Clinical Investigation. PMID 27941241 DOI: 10.1172/Jci88015  0.474
2016 Brereton MF, Rohm M, Shimomura K, Holland C, Tornovsky-Babeay S, Dadon D, Iberl M, Chibalina MV, Lee S, Glaser B, Dor Y, Rorsman P, Clark A, Ashcroft FM. Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells. Nature Communications. 7: 13496. PMID 27882918 DOI: 10.1038/Ncomms13496  0.467
2016 Dahan T, Ziv O, Horwitz E, Zemmour H, Lavi J, Swisa A, Leibowitz G, Ashcroft FM, Veld PI, Glaser B, Dor Y. Pancreatic Beta Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes. Diabetes. PMID 27864307 DOI: 10.2337/Db16-0641  0.516
2016 Azizoglu DB, Chong DC, Villasenor A, Magenheim J, Barry DM, Lee S, Marty-Santos L, Fu S, Dor Y, Cleaver O. Vascular development in the vertebrate pancreas. Developmental Biology. PMID 27789228 DOI: 10.1016/J.Ydbio.2016.10.009  0.338
2016 Malakar P, Chartarifsky L, Hija A, Leibowitz G, Glaser B, Dor Y, Karni R. Insulin receptor alternative splicing is regulated by insulin signaling and modulates beta cell survival. Scientific Reports. 6: 31222. PMID 27526875 DOI: 10.1038/Srep31222  0.445
2016 Hashimshony T, Senderovich N, Avital G, Klochendler A, de Leeuw Y, Anavy L, Gennert D, Li S, Livak KJ, Rozenblatt-Rosen O, Dor Y, Regev A, Yanai I. CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq. Genome Biology. 17: 77. PMID 27121950 DOI: 10.1186/S13059-016-0938-8  0.377
2016 Klochendler A, Caspi I, Corem N, Moran M, Friedlich O, Elgavish S, Nevo Y, Helman A, Glaser B, Eden A, Itzkovitz S, Dor Y. The genetic program of pancreatic beta-cell replication in vivo. Diabetes. PMID 26993067 DOI: 10.2337/Db16-0003  0.468
2016 Lehmann-Werman R, Neiman D, Zemmour H, Moss J, Magenheim J, Vaknin-Dembinsky A, Rubertsson S, Nellgård B, Blennow K, Zetterberg H, Spalding K, Haller MJ, Wasserfall CH, Schatz DA, Greenbaum CJ, ... ... Dor Y, et al. Identification of tissue-specific cell death using methylation patterns of circulating DNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976580 DOI: 10.1073/Pnas.1519286113  0.394
2016 Helman A, Klochendler A, Azazmeh N, Gabai Y, Horwitz E, Anzi S, Swisa A, Condiotti R, Granit RZ, Nevo Y, Fixler Y, Shreibman D, Zamir A, Tornovsky-Babeay S, Dai C, ... ... Dor Y, et al. p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion. Nature Medicine. PMID 26950362 DOI: 10.1038/Nm.4054  0.497
2016 Wittenberg AD, Azar S, Klochendler A, Stolovich-Rain M, Avraham S, Birnbaum L, Binder Gallimidi A, Katz M, Dor Y, Meyuhas O. Phosphorylated Ribosomal Protein S6 Is Required for Akt-Driven Hyperplasia and Malignant Transformation, but Not for Hypertrophy, Aneuploidy and Hyperfunction of Pancreatic β-Cells. Plos One. 11: e0149995. PMID 26919188 DOI: 10.1371/Journal.Pone.0149995  0.425
2015 Swisa A, Granot Z, Tamarina N, Sayers S, Bardeesy N, Philipson L, Hodson DJ, Wikstrom JD, Rutter GA, Leibowitz G, Glaser B, Dor Y. Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects. The Journal of Biological Chemistry. 290: 20934-46. PMID 26139601 DOI: 10.1074/Jbc.M115.639237  0.462
2015 Stolovich-Rain M, Enk J, Vikesa J, Nielsen FC, Saada A, Glaser B, Dor Y. Weaning triggers a maturation step of pancreatic β cells. Developmental Cell. 32: 535-45. PMID 25662175 DOI: 10.1016/J.Devcel.2015.01.002  0.473
2014 Kone M, Pullen TJ, Sun G, Ibberson M, Martinez-Sanchez A, Sayers S, Nguyen-Tu MS, Kantor C, Swisa A, Dor Y, Gorman T, Ferrer J, Thorens B, Reimann F, Gribble F, et al. LKB1 and AMPK differentially regulate pancreatic β-cell identity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4972-85. PMID 25070369 DOI: 10.1096/Fj.14-257667  0.409
2014 Chen YJ, Finkbeiner SR, Weinblatt D, Emmett MJ, Tameire F, Yousefi M, Yang C, Maehr R, Zhou Q, Shemer R, Dor Y, Li C, Spence JR, Stanger BZ. De novo formation of insulin-producing "neo-β cell islets" from intestinal crypts. Cell Reports. 6: 1046-58. PMID 24613355 DOI: 10.1016/J.Celrep.2014.02.013  0.764
2014 Tornovsky-Babeay S, Dadon D, Ziv O, Tzipilevich E, Kadosh T, Schyr-Ben Haroush R, Hija A, Stolovich-Rain M, Furth-Lavi J, Granot Z, Porat S, Philipson LH, Herold KC, Bhatti TR, Stanley C, ... ... Dor Y, et al. Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells. Cell Metabolism. 19: 109-21. PMID 24332968 DOI: 10.1016/J.Cmet.2013.11.007  0.415
2014 Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, et al. Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Nature Biotechnology. 32: 76-83. PMID 24240391 DOI: 10.1038/Nbt.2747  0.546
2014 Hija A, Salpeter S, Klochendler A, Grimsby J, Brandeis M, Glaser B, Dor Y. G0-G1 transition and the restriction point in pancreatic β-cells in vivo. Diabetes. 63: 578-84. PMID 24130333 DOI: 10.2337/Db12-1035  0.439
2014 De Leu N, Heremans Y, Coppens V, Van Gassen N, Cai Y, D'Hoker J, Magenheim J, Salpeter S, Swisa A, Khalaileh A, Arnold C, Gradwohl G, Van de Casteele M, Keshet E, Dor Y, et al. Short-term overexpression of VEGF-A in mouse beta cells indirectly stimulates their proliferation and protects against diabetes. Diabetologia. 57: 140-7. PMID 24121626 DOI: 10.1007/S00125-013-3076-9  0.465
2013 Gur C, Enk J, Weitman E, Bachar E, Suissa Y, Cohen G, Schyr RB, Sabanay H, Horwitz E, Glaser B, Dor Y, Pribluda A, Hanna JH, Leibowitz G, Mandelboim O. The expression of the beta cell-derived autoimmune ligand for the killer receptor nkp46 is attenuated in type 2 diabetes. Plos One. 8: e74033. PMID 24009765 DOI: 10.1371/Journal.Pone.0074033  0.452
2013 Wikstrom JD, Israeli T, Bachar-Wikstrom E, Swisa A, Ariav Y, Waiss M, Kaganovich D, Dor Y, Cerasi E, Leibowitz G. AMPK regulates ER morphology and function in stressed pancreatic β-cells via phosphorylation of DRP1. Molecular Endocrinology (Baltimore, Md.). 27: 1706-23. PMID 23979843 DOI: 10.1210/Me.2013-1109  0.316
2013 D'Hoker J, De Leu N, Heremans Y, Baeyens L, Minami K, Ying C, Lavens A, Chintinne M, Stangé G, Magenheim J, Swisa A, Martens G, Pipeleers D, van de Casteele M, Seino S, ... ... Dor Y, et al. Conditional hypovascularization and hypoxia in islets do not overtly influence adult β-cell mass or function. Diabetes. 62: 4165-73. PMID 23974922 DOI: 10.2337/Db12-1827  0.486
2013 Suissa Y, Magenheim J, Stolovich-Rain M, Hija A, Collombat P, Mansouri A, Sussel L, Sosa-Pineda B, McCracken K, Wells JM, Heller RS, Dor Y, Glaser B. Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas. Plos One. 8: e70397. PMID 23940571 DOI: 10.1371/Journal.Pone.0070397  0.527
2013 Ziv O, Glaser B, Dor Y. The plastic pancreas. Developmental Cell. 26: 3-7. PMID 23867225 DOI: 10.1016/J.Devcel.2013.06.013  0.497
2013 Salpeter SJ, Khalaileh A, Weinberg-Corem N, Ziv O, Glaser B, Dor Y. Systemic regulation of the age-related decline of pancreatic β-cell replication. Diabetes. 62: 2843-8. PMID 23630298 DOI: 10.2337/Db13-0160  0.429
2013 Van de Casteele M, Leuckx G, Baeyens L, Cai Y, Yuchi Y, Coppens V, De Groef S, Eriksson M, Svensson C, Ahlgren U, Ahnfelt-Rønne J, Madsen OD, Waisman A, Dor Y, Jensen JN, et al. Neurogenin 3+ cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas. Cell Death & Disease. 4: e523. PMID 23470530 DOI: 10.1038/Cddis.2013.52  0.534
2013 Dor Y, Glaser B. β-cell dedifferentiation and type 2 diabetes. The New England Journal of Medicine. 368: 572-3. PMID 23388011 DOI: 10.1056/Nejmcibr1214034  0.431
2013 Khalaileh A, Dreazen A, Khatib A, Apel R, Swisa A, Kidess-Bassir N, Maitra A, Meyuhas O, Dor Y, Zamir G. Phosphorylation of ribosomal protein S6 attenuates DNA damage and tumor suppression during development of pancreatic cancer. Cancer Research. 73: 1811-20. PMID 23361300 DOI: 10.1158/0008-5472.Can-12-2014  0.329
2013 Salpeter S, Khalaileh A, Weinberg-Corem N, Ziv O, Glaser B, Dor Y. Systemic regulation of the age-related decline of pancreatic β-cell replication. Diabetes 2013;62:2843–2848 Diabetes. 62: 3300-3300. DOI: 10.2337/Db13-Er09  0.324
2013 Dor Y, Melton DA. Pancreatic Stem Cells Essentials of Stem Cell Biology: Third Edition. 329-342. DOI: 10.1016/B978-0-12-409503-8.00024-X  0.312
2013 Dor Y, Melton DA. Pancreatic Stem Cells Handbook of Stem Cells. 2: 819-826. DOI: 10.1016/B978-0-12-385942-6.00068-8  0.554
2012 Boj SF, van Es JH, Huch M, Li VS, José A, Hatzis P, Mokry M, Haegebarth A, van den Born M, Chambon P, Voshol P, Dor Y, Cuppen E, Fillat C, Clevers H. Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 151: 1595-607. PMID 23260145 DOI: 10.1016/J.Cell.2012.10.053  0.344
2012 Klochendler A, Weinberg-Corem N, Moran M, Swisa A, Pochet N, Savova V, Vikeså J, Van de Peer Y, Brandeis M, Regev A, Nielsen FC, Dor Y, Eden A. A transgenic mouse marking live replicating cells reveals in vivo transcriptional program of proliferation. Developmental Cell. 23: 681-90. PMID 23000141 DOI: 10.1016/J.Devcel.2012.08.009  0.461
2012 Mandelbaum AD, Melkman-Zehavi T, Oren R, Kredo-Russo S, Nir T, Dor Y, Hornstein E. Dysregulation of Dicer1 in beta cells impairs islet architecture and glucose metabolism. Experimental Diabetes Research. 2012: 470302. PMID 22991506 DOI: 10.1155/2012/470302  0.462
2012 Dadon D, Tornovsky-Babaey S, Furth-Lavi J, Ben-Zvi D, Ziv O, Schyr-Ben-Haroush R, Stolovich-Rain M, Hija A, Porat S, Granot Z, Weinberg-Corem N, Dor Y, Glaser B. Glucose metabolism: key endogenous regulator of β-cell replication and survival. Diabetes, Obesity & Metabolism. 14: 101-8. PMID 22928570 DOI: 10.1111/J.1463-1326.2012.01646.X  0.706
2012 Cleaver O, Dor Y. Vascular instruction of pancreas development. Development (Cambridge, England). 139: 2833-43. PMID 22833471 DOI: 10.1242/Dev.065953  0.38
2012 Kaufman-Francis K, Koffler J, Weinberg N, Dor Y, Levenberg S. Engineered vascular beds provide key signals to pancreatic hormone-producing cells. Plos One. 7: e40741. PMID 22808248 DOI: 10.1371/Journal.Pone.0040741  0.401
2012 Stolovich-Rain M, Hija A, Grimsby J, Glaser B, Dor Y. Pancreatic beta cells in very old mice retain capacity for compensatory proliferation. The Journal of Biological Chemistry. 287: 27407-14. PMID 22740691 DOI: 10.1074/Jbc.M112.350736  0.46
2012 Prévot PP, Simion A, Grimont A, Colletti M, Khalaileh A, Van den Steen G, Sempoux C, Xu X, Roelants V, Hald J, Bertrand L, Heimberg H, Konieczny SF, Dor Y, Lemaigre FP, et al. Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia. Gut. 61: 1723-32. PMID 22271799 DOI: 10.1136/Gutjnl-2011-300266  0.315
2011 Magenheim J, Ilovich O, Lazarus A, Klochendler A, Ziv O, Werman R, Hija A, Cleaver O, Mishani E, Keshet E, Dor Y. Blood vessels restrain pancreas branching, differentiation and growth. Development (Cambridge, England). 138: 4743-52. PMID 21965615 DOI: 10.1242/Dev.066548  0.405
2011 Magenheim J, Klein AM, Stanger BZ, Ashery-Padan R, Sosa-Pineda B, Gu G, Dor Y. Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium. Developmental Biology. 359: 26-36. PMID 21888903 DOI: 10.1016/J.Ydbio.2011.08.006  0.525
2011 Gur C, Enk J, Kassem SA, Suissa Y, Magenheim J, Stolovich-Rain M, Nir T, Achdout H, Glaser B, Shapiro J, Naparstek Y, Porgador A, Dor Y, Mandelboim O. Recognition and killing of human and murine pancreatic beta cells by the NK receptor NKp46. Journal of Immunology (Baltimore, Md. : 1950). 187: 3096-103. PMID 21849674 DOI: 10.4049/Jimmunol.1101269  0.474
2011 Salpeter SJ, Klochendler A, Weinberg-Corem N, Porat S, Granot Z, Shapiro AM, Magnuson MA, Eden A, Grimsby J, Glaser B, Dor Y. Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channels. Endocrinology. 152: 2589-98. PMID 21521747 DOI: 10.1210/En.2010-1372  0.413
2011 Porat S, Weinberg-Corem N, Tornovsky-Babaey S, Schyr-Ben-Haroush R, Hija A, Stolovich-Rain M, Dadon D, Granot Z, Ben-Hur V, White P, Girard CA, Karni R, Kaestner KH, Ashcroft FM, Magnuson MA, ... ... Dor Y, et al. Control of pancreatic β cell regeneration by glucose metabolism. Cell Metabolism. 13: 440-9. PMID 21459328 DOI: 10.1016/J.Cmet.2011.02.012  0.488
2011 Melkman-Zehavi T, Oren R, Kredo-Russo S, Shapira T, Mandelbaum AD, Rivkin N, Nir T, Lennox KA, Behlke MA, Dor Y, Hornstein E. miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors. The Embo Journal. 30: 835-45. PMID 21285947 DOI: 10.1038/Emboj.2010.361  0.352
2011 Sand FW, Hörnblad A, Johansson JK, Lorén C, Edsbagge J, Ståhlberg A, Magenheim J, Ilovich O, Mishani E, Dor Y, Ahlgren U, Semb H. Growth-limiting role of endothelial cells in endoderm development. Developmental Biology. 352: 267-77. PMID 21281624 DOI: 10.1016/J.Ydbio.2011.01.026  0.404
2011 Schlager A, Khalaileh A, Mintz Y, Abu Gazala M, Globerman A, Ilani N, Rivkind AI, Salpeter S, Dor Y, Zamir G. A mouse model for sleeve gastrectomy: applications for diabetes research. Microsurgery. 31: 66-71. PMID 20734435 DOI: 10.1002/Micr.20797  0.387
2011 Khatib AAS, Dor Y, Khalilah A. Abstract A51: The role of ribosomal protein s6 in the development of pancreatic cancer precursor lesions Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A51  0.317
2010 Salpeter SJ, Klein AM, Huangfu D, Grimsby J, Dor Y. Glucose and aging control the quiescence period that follows pancreatic beta cell replication. Development (Cambridge, England). 137: 3205-13. PMID 20823063 DOI: 10.1242/Jcs.080713  0.713
2010 Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, et al. The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell. 140: 280-93. PMID 20141841 DOI: 10.1016/J.Cell.2009.12.041  0.354
2010 Gur C, Porgador A, Elboim M, Gazit R, Mizrahi S, Stern-Ginossar N, Achdout H, Ghadially H, Dor Y, Nir T, Doviner V, Hershkovitz O, Mendelson M, Naparstek Y, Mandelboim O. The activating receptor NKp46 is essential for the development of type 1 diabetes. Nature Immunology. 11: 121-8. PMID 20023661 DOI: 10.1038/Ni.1834  0.402
2009 Granot Z, Swisa A, Magenheim J, Stolovich-Rain M, Fujimoto W, Manduchi E, Miki T, Lennerz JK, Stoeckert CJ, Meyuhas O, Seino S, Permutt MA, Piwnica-Worms H, Bardeesy N, Dor Y. LKB1 regulates pancreatic beta cell size, polarity, and function. Cell Metabolism. 10: 296-308. PMID 19808022 DOI: 10.1016/J.Cmet.2009.08.010  0.493
2009 Wang S, Jensen JN, Seymour PA, Hsu W, Dor Y, Sander M, Magnuson MA, Serup P, Gu G. Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proceedings of the National Academy of Sciences of the United States of America. 106: 9715-20. PMID 19487660 DOI: 10.1073/Pnas.0904247106  0.5
2008 Setty Y, Cohen IR, Dor Y, Harel D. Four-dimensional realistic modeling of pancreatic organogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 20374-9. PMID 19091945 DOI: 10.1073/Pnas.0808725105  0.314
2008 Khalaileh A, Gonen-Gross T, Magenheim J, Nir T, Porat S, Salpeter S, Stolovich-Rain M, Swisa A, Weinberg N, Dor Y. Determinants of pancreatic beta-cell regeneration. Diabetes, Obesity & Metabolism. 10: 128-35. PMID 18834440 DOI: 10.1111/J.1463-1326.2008.00948.X  0.508
2008 Fendrich V, Esni F, Garay MV, Feldmann G, Habbe N, Jensen JN, Dor Y, Stoffers D, Jensen J, Leach SD, Maitra A. Hedgehog signaling is required for effective regeneration of exocrine pancreas. Gastroenterology. 135: 621-31. PMID 18515092 DOI: 10.1053/J.Gastro.2008.04.011  0.457
2008 Wasserstrom A, Frumkin D, Adar R, Itzkovitz S, Stern T, Kaplan S, Shefer G, Shur I, Zangi L, Reizel Y, Harmelin A, Dor Y, Dekel N, Reisner Y, Benayahu D, et al. Estimating cell depth from somatic mutations. Plos Computational Biology. 4: e1000058. PMID 18404205 DOI: 10.1371/Journal.Pcbi.1000058  0.443
2008 Wang S, Hecksher-Sorensen J, Xu Y, Zhao A, Dor Y, Rosenberg L, Serup P, Gu G. Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation. Developmental Biology. 317: 531-40. PMID 18394599 DOI: 10.1016/J.Ydbio.2008.02.052  0.425
2008 Dor Y, Melton DA. Facultative endocrine progenitor cells in the adult pancreas. Cell. 132: 183-4. PMID 18243094 DOI: 10.1016/J.Cell.2008.01.004  0.656
2008 Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA. Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Molecular and Cellular Biology. 28: 2414-25. PMID 18227155 DOI: 10.1128/Mcb.01621-07  0.427
2008 Gu G, Wang S, Zhao A, Xu Y, Dor Y. Ngn3 expression in differentiated islet cells contributes to islet cell maintenance and function Developmental Biology. 319: 607. DOI: 10.1016/J.Ydbio.2008.05.455  0.5
2008 Salpeter SJ, Dor Y. Beta-cell replication Pancreatic Beta Cell in Health and Disease. 245-263. DOI: 10.1007/978-4-431-75452-7_13  0.313
2007 Strobel O, Dor Y, Alsina J, Stirman A, Lauwers G, Trainor A, Castillo CF, Warshaw AL, Thayer SP. In vivo lineage tracing defines the role of acinar-to-ductal transdifferentiation in inflammatory ductal metaplasia. Gastroenterology. 133: 1999-2009. PMID 18054571 DOI: 10.1053/J.Gastro.2007.09.009  0.376
2007 Nir T, Melton DA, Dor Y. Recovery from diabetes in mice by beta cell regeneration. The Journal of Clinical Investigation. 117: 2553-61. PMID 17786244 DOI: 10.1172/Jci32959  0.651
2007 Porat S, Dor Y. New sources of pancreatic beta cells. Current Diabetes Reports. 7: 304-8. PMID 17686408 DOI: 10.1007/S11892-007-0049-8  0.513
2007 Strobel O, Dor Y, Stirman A, Trainor A, Fernández-del Castillo C, Warshaw AL, Thayer SP. Beta cell transdifferentiation does not contribute to preneoplastic/metaplastic ductal lesions of the pancreas by genetic lineage tracing in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 4419-24. PMID 17360539 DOI: 10.1073/Pnas.0605248104  0.496
2007 Weinberg N, Ouziel-Yahalom L, Knoller S, Efrat S, Dor Y. Lineage tracing evidence for in vitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells. Diabetes. 56: 1299-304. PMID 17303800 DOI: 10.2337/Db06-1654  0.49
2006 Salpeter SJ, Dor Y. Pancreatic cells and their progenitors. Methods in Enzymology. 419: 322-37. PMID 17141061 DOI: 10.1016/S0076-6879(06)19013-8  0.522
2006 Dor Y. beta-Cell proliferation is the major source of new pancreatic beta cells. Nature Clinical Practice. Endocrinology & Metabolism. 2: 242-3. PMID 16932291 DOI: 10.1038/Ncpendmet0187  0.529
2006 Grunewald M, Avraham I, Dor Y, Bachar-Lustig E, Itin A, Jung S, Yung S, Chimenti S, Landsman L, Abramovitch R, Keshet E. VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell. 124: 175-89. PMID 16413490 DOI: 10.1016/J.Cell.2005.10.036  0.389
2006 Stanger BZ, Dor Y. Dissecting the cellular origins of pancreatic cancer. Cell Cycle (Georgetown, Tex.). 5: 43-6. PMID 16322695 DOI: 10.4161/Cc.5.1.2291  0.417
2006 Horiguchi M, Kawaguchi Y, Kodama S, Furuyama K, Fukuda A, Kuhara T, Fujimoto K, Dor Y, Wright C, Doi R. Adult pancreatic exocrine tissue is maintained by self-duplication of the existing cells Journal of Surgical Research. 130: 285. DOI: 10.1016/J.Jss.2005.11.360  0.376
2006 Grunewald M, Avraham I, Dor Y, Bachar-Lustig E, Itin A, Yung S, Chimenti S, Landsman L, Abramovitch R, Keshet E. VEGF-Induced Adult Neovascularization: Recruitment, Retention, and Role of Accessory Cells (DOI:10.1016/j.cell.2005.10.036) Cell. 126: 811. DOI: 10.1016/j.cell.2006.08.015  0.331
2005 Murtaugh LC, Law AC, Dor Y, Melton DA. Beta-catenin is essential for pancreatic acinar but not islet development. Development (Cambridge, England). 132: 4663-74. PMID 16192304 DOI: 10.1242/Dev.02063  0.626
2005 Stanger BZ, Stiles B, Lauwers GY, Bardeesy N, Mendoza M, Wang Y, Greenwood A, Cheng KH, McLaughlin M, Brown D, Depinho RA, Wu H, Melton DA, Dor Y. Pten constrains centroacinar cell expansion and malignant transformation in the pancreas. Cancer Cell. 8: 185-95. PMID 16169464 DOI: 10.1016/J.Ccr.2005.07.015  0.735
2005 Ruvinsky I, Sharon N, Lerer T, Cohen H, Stolovich-Rain M, Nir T, Dor Y, Zisman P, Meyuhas O. Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis. Genes & Development. 19: 2199-211. PMID 16166381 DOI: 10.1101/Gad.351605  0.467
2005 Nir T, Dor Y. How to make pancreatic beta cells--prospects for cell therapy in diabetes. Current Opinion in Biotechnology. 16: 524-9. PMID 16084716 DOI: 10.1016/J.Copbio.2005.07.005  0.521
2005 Karni R, Gus Y, Dor Y, Meyuhas O, Levitzki A. Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation. Molecular and Cellular Biology. 25: 5031-9. PMID 15923620 DOI: 10.1128/Mcb.25.12.5031-5039.2005  0.337
2004 Dor Y, Melton DA. How important are adult stem cells for tissue maintenance? Cell Cycle (Georgetown, Tex.). 3: 1104-6. PMID 15326371 DOI: 10.4161/Cc.3.9.1096  0.641
2004 Dor Y, Brown J, Martinez OI, Melton DA. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature. 429: 41-6. PMID 15129273 DOI: 10.1038/Nature02520  0.74
2003 Amsterdam A, Sasson R, Keren-Tal I, Aharoni D, Dantes A, Rimon E, Land A, Cohen T, Dor Y, Hirsh L. Alternative pathways of ovarian apoptosis: death for life. Biochemical Pharmacology. 66: 1355-62. PMID 14555209 DOI: 10.1016/S0006-2952(03)00485-4  0.31
1999 Raboy B, Marom A, Dor Y, Kulka RG. Heat-induced cell cycle arrest of Saccharomyces cerevisiae: involvement of the RAD6/UBC2 and WSC2 genes in its reversal. Molecular Microbiology. 32: 729-39. PMID 10361277 DOI: 10.1046/J.1365-2958.1999.01389.X  0.385
1998 Carmeliet P, Dor Y, Herbert JM, Fukumura D, Brusselmans K, Dewerchin M, Neeman M, Bono F, Abramovitch R, Maxwell P, Koch CJ, Ratcliffe P, Moons L, Jain RK, Collen D, et al. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature. 394: 485-90. PMID 9697772 DOI: 10.1038/28867  0.305
1998 Carmeliet P, Dor Y, Herbert J, Fukumura D, Brusselmans K, Dewerchin M, Neeman M, Bono F, Abramovitch R, Maxwell P, Koch CJ, Ratcliffe P, Moons L, Jain RK, Collen D, et al. Erratum: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis Nature. 395: 525-525. DOI: 10.1038/26791  0.348
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