Year |
Citation |
Score |
2024 |
Chhabra G, Singh CK, Ndiaye MA, Su S, Shirley CA, Ahmad N. Role of PLK1/NUMB/NOTCH in epithelial-mesenchymal transition in human melanoma. Npj Precision Oncology. 8: 6. PMID 38184733 DOI: 10.1038/s41698-023-00493-7 |
0.3 |
|
2023 |
Su S, Ndiaye MA, Guzmán-Pérez G, Baus RM, Huang W, Patankar MS, Ahmad N. Potential Tumor Suppressor Role of Polo-like Kinase 5 in Cancer. Cancers. 15. PMID 38001717 DOI: 10.3390/cancers15225457 |
0.37 |
|
2022 |
Dong B, Simonson L, Vold S, Oldham E, Barten L, Ahmad N, Chang H. Frizzled 6 promotes melanoma cell invasion but not proliferation by regulating canonical Wnt signaling and EMT. The Journal of Investigative Dermatology. PMID 36368445 DOI: 10.1016/j.jid.2022.09.658 |
0.331 |
|
2022 |
Singh CK, Denu RA, Nihal M, Shabbir M, Garvey DR, Huang W, Iczkowski KA, Ahmad N. PLK4 is upregulated in prostate cancer and its inhibition reduces centrosome amplification and causes senescence. The Prostate. PMID 35333404 DOI: 10.1002/pros.24342 |
0.36 |
|
2021 |
Su S, Chhabra G, Singh CK, Ndiaye MA, Ahmad N. PLK1 inhibition-based combination therapies for cancer management. Translational Oncology. 16: 101332. PMID 34973570 DOI: 10.1016/j.tranon.2021.101332 |
0.37 |
|
2021 |
Singh CK, George J, Chhabra G, Nihal M, Chang H, Ahmad N. Genetic Manipulation of Sirtuin 3 Causes Alterations of Key Metabolic Regulators in Melanoma. Frontiers in Oncology. 11: 676077. PMID 33937086 DOI: 10.3389/fonc.2021.676077 |
0.309 |
|
2021 |
Chhabra G, Singh CK, Amiri D, Akula N, Ahmad N. Recent Advancements on Immunomodulatory Mechanisms of Resveratrol in Tumor Microenvironment. Molecules (Basel, Switzerland). 26. PMID 33802331 DOI: 10.3390/molecules26051343 |
0.351 |
|
2021 |
Garvey DR, Chhabra G, Ndiaye MA, Ahmad N. Role of polo-like kinase 4 (PLK4) in epithelial cancers and recent progress in its small molecule targeting for cancer management. Molecular Cancer Therapeutics. PMID 33402398 DOI: 10.1158/1535-7163.MCT-20-0741 |
0.43 |
|
2020 |
Su S, Chhabra G, Ndiaye MA, Singh CK, Ye T, Huang W, Dewey CN, Setaluri V, Ahmad N. PLK1 and NOTCH Positively Correlate in Melanoma and their Combined Inhibition Results in Synergistic Modulations of Key Melanoma Pathways. Molecular Cancer Therapeutics. PMID 33177155 DOI: 10.1158/1535-7163.MCT-20-0654 |
0.325 |
|
2020 |
Singh CK, Chhabra G, Ndiaye MA, Siddiqui IA, Panackal JE, Mintie CA, Ahmad N. Quercetin-Resveratrol Combination for Prostate Cancer Management in TRAMP Mice. Cancers. 12. PMID 32748838 DOI: 10.3390/Cancers12082141 |
0.492 |
|
2020 |
Mintie CA, Musarra AK, Singh CK, Ndiaye MA, Sullivan R, Eickhoff JC, Ahmad N. Protective Effects of Dietary Grape on UVB-Mediated Cutaneous Damages and Skin Tumorigenesis in SKH-1 Mice. Cancers. 12. PMID 32630288 DOI: 10.3390/Cancers12071751 |
0.375 |
|
2020 |
Garcia-Peterson LM, Ndiaye MA, Chhabra G, Singh CK, Guzmán-Pérez G, Iczkowski KA, Ahmad N. CRISPR/Cas9-mediated Knockout of SIRT6 Imparts Remarkable Anti-proliferative Response in Human Melanoma Cells in vitro and in vivo. Photochemistry and Photobiology. PMID 32621766 DOI: 10.1111/Php.13305 |
0.474 |
|
2020 |
Su S, Ndiaye MA, Singh CK, Ahmad N. Mitochondrial Sirtuins in Skin and Skin Cancers. Photochemistry and Photobiology. PMID 32124989 DOI: 10.1111/Php.13254 |
0.374 |
|
2019 |
Mintie CA, Singh CK, Ahmad N. Whole Fruit Phytochemicals Combating Skin Damage and Carcinogenesis. Translational Oncology. 13: 146-156. PMID 31865177 DOI: 10.1016/J.Tranon.2019.10.014 |
0.333 |
|
2019 |
Garcia-Peterson LM, Guzmán-Pérez G, Krier CR, Ahmad N. The sirtuin 6: An overture in skin cancer. Experimental Dermatology. PMID 31696978 DOI: 10.1111/Exd.14057 |
0.454 |
|
2019 |
Mintie CA, Singh CK, Ndiaye MA, Barrett-Wilt GA, Ahmad N. Identification of Molecular Targets of Dietary Grape-Mediated Chemoprevention of Ultraviolet B Skin Carcinogenesis: A Comparative Quantitative Proteomics Analysis. Journal of Proteome Research. PMID 31487184 DOI: 10.1021/Acs.Jproteome.9B00442 |
0.333 |
|
2019 |
George J, Nihal M, Singh CK, Ahmad N. 4'-Bromo-resveratrol, a dual Sirtuin-1 and Sirtuin-3 inhibitor, inhibits melanoma cell growth through mitochondrial metabolic reprogramming. Molecular Carcinogenesis. PMID 31292999 DOI: 10.1002/Mc.23080 |
0.467 |
|
2019 |
Bai Y, Zhang Z, Cheng L, Wang R, Chen X, Kong Y, Feng F, Ahmad N, Li L, Liu X. Inhibition of enhancer of zeste homolog 2 (EZH2) overcomes enzalutamide-resistance in castration-resistance prostate cancer. The Journal of Biological Chemistry. PMID 31085587 DOI: 10.1074/Jbc.Ra119.008152 |
0.428 |
|
2019 |
Farah E, Li C, Cheng L, Kong Y, Lanman NA, Pascuzzi PE, Lorenz GR, Zhang Y, Ahmad N, Li L, Ratliff T, Liu X. NOTCH signaling is activated in and contributes to resistance in enzalutamide-resistant prostate cancer cells. The Journal of Biological Chemistry. PMID 30940724 DOI: 10.1074/Jbc.Ra118.006983 |
0.459 |
|
2019 |
Su S, Chhabra G, Singh CK, Ndiaye MA, Ahmad N. Abstract 302: The combined inhibition of Plk1 and Notch1 results in a synergistic anti-proliferative response in human melanoma cells Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-302 |
0.386 |
|
2019 |
Ndiaye MA, Su S, Baus RM, Huang W, Patankar MS, Ahmad N. Abstract 1251: Potential tumor suppressor function of polo-like kinase 5 in ovarian cancers Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-1251 |
0.4 |
|
2019 |
Singh CK, Ndiaye MA, Chhabra G, Mintie CA, Ahmad N. Abstract 5085: Molecular analysis of chemopreventive effects of grape antioxidants resveratrol and quercetin in transgenic adenocarcinoma of the mouse prostate Cancer Research. 79: 5085-5085. DOI: 10.1158/1538-7445.Am2019-5085 |
0.491 |
|
2019 |
Garvey D, Ndiaye M, Ahmad N. 1033 The potential pro-proliferative role of polo-like kinase 4 in non-melanoma skin cancer Journal of Investigative Dermatology. 139: S178. DOI: 10.1016/J.Jid.2019.03.1109 |
0.425 |
|
2018 |
Singh CK, Mintie CA, Ndiaye MA, Chhabra G, Dakup PP, Ye T, Yu M, Ahmad N. Chemoprotective effects of dietary grape powder on ultraviolet B radiation-mediated skin carcinogenesis in SKH-1 hairless mice. The Journal of Investigative Dermatology. PMID 30393084 DOI: 10.1016/J.Jid.2018.09.028 |
0.412 |
|
2018 |
Chhabra G, Garvey DR, Singh CK, Mintie CA, Ahmad N. Effects and Mechanism of Nicotinamide Against UVA- and/or UVB-mediated DNA Damages in Normal Melanocytes. Photochemistry and Photobiology. PMID 30102774 DOI: 10.1111/Php.12994 |
0.387 |
|
2018 |
Kong Y, Cheng L, Mao F, Zhang Z, Zhang Y, Farah E, Bosler J, Bai Y, Ahmad N, Kuang S, Li L, Liu X. Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC). The Journal of Biological Chemistry. PMID 30089652 DOI: 10.1074/Jbc.Ra118.004442 |
0.456 |
|
2018 |
Chhabra G, Singh CK, Ndiaye MA, Fedorowicz S, Molot A, Ahmad N. Prostate cancer chemoprevention by natural agents: Clinical evidence and potential implications. Cancer Letters. PMID 29471004 DOI: 10.1016/j.canlet.2018.02.025 |
0.336 |
|
2018 |
Denu RA, Shabbir M, Nihal M, Singh CK, Longley BJ, Burkard ME, Ahmad N. Centriole Overduplication is the Predominant Mechanism Leading to Centrosome Amplification in Melanoma. Molecular Cancer Research : McR. PMID 29330283 DOI: 10.1158/1541-7786.Mcr-17-0197 |
0.342 |
|
2018 |
Garcia-Peterson LM, Ndiaye MA, Singh CK, Chhabra G, Ahmad N. Abstract 548: The effects of Sirtuin 6 inhibition on autophagy-related pathways in melanoma Cancer Research. 78: 548-548. DOI: 10.1158/1538-7445.Am2018-548 |
0.481 |
|
2018 |
Singh CK, Chhabra G, Nihal M, Iczkowski KA, Ahmad N. Abstract 539: Pro-proliferative function of the histone deacetylase SIRT3 in prostate cancer Cancer Research. 78: 539-539. DOI: 10.1158/1538-7445.Am2018-539 |
0.568 |
|
2018 |
Su S, Singh CK, Ndiaye MA, Setaluri V, Ahmad N. Abstract 2530: An analysis of correlative interactions between Plk1, Notch1 and FoxM1 in melanoma Cancer Research. 78: 2530-2530. DOI: 10.1158/1538-7445.Am2018-2530 |
0.432 |
|
2018 |
Chhabra G, Singh CK, Ndiaye MA, Ahmad N. Abstract 2016: Potential role of polo-like kinase 1 in epithelial-mesenchymal transition in melanoma Tumor Biology. DOI: 10.1158/1538-7445.Am2018-2016 |
0.306 |
|
2018 |
Mintie CA, Singh CK, Ndiaye MA, Barrett-Wilt GA, Ahmad N. Abstract 1260: Mechanism of skin cancer chemoprevention by dietary grape: A global proteomics approach Cancer Research. 78: 1260-1260. DOI: 10.1158/1538-7445.Am2018-1260 |
0.442 |
|
2018 |
Garcia-Peterson L, Ndiaye M, Singh C, Chhabra G, Ahmad N. 1263 Involvement of SIRT6 deacetylase in autophagy regulation in melanoma Journal of Investigative Dermatology. 138: S214. DOI: 10.1016/J.Jid.2018.03.1278 |
0.336 |
|
2018 |
Chhabra G, Singh C, Ndiaye M, Ahmad N. 1258 Plk1 phosphorylates Numb and promotes EMT in melanoma Journal of Investigative Dermatology. 138: S213. DOI: 10.1016/J.Jid.2018.03.1273 |
0.307 |
|
2017 |
Garcia-Peterson LM, Ndiaye MA, Singh CK, Chhabra G, Huang W, Ahmad N. SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. Genes & Cancer. 8: 701-712. PMID 29234488 DOI: 10.18632/Genesandcancer.153 |
0.474 |
|
2017 |
Wilking-Busch MJ, Ndiaye MA, Liu X, Ahmad N. RNA interference-mediated knockdown of SIRT1 and/or SIRT2 in melanoma: Identification of downstream targets by large-scale proteomics analysis. Journal of Proteomics. PMID 28882678 DOI: 10.1016/j.jprot.2017.09.002 |
0.338 |
|
2017 |
Seenivasan R, Singh CK, Warrick JW, Ahmad N, Gunasekaran S. Microfluidic-integrated patterned ITO immunosensor for rapid detection of prostate-specific membrane antigen biomarker in prostate cancer. Biosensors & Bioelectronics. 95: 160-167. PMID 28445813 DOI: 10.1016/J.Bios.2017.04.004 |
0.394 |
|
2017 |
Chhabra G, Ndiaye MA, Garcia-Peterson LM, Ahmad N. Melanoma Chemoprevention: Current Status and Future Prospects. Photochemistry and Photobiology. PMID 28295364 DOI: 10.1111/Php.12749 |
0.408 |
|
2017 |
Gutteridge RE, Singh CK, Ndiaye MA, Ahmad N. Targeted knockdown of polo-like kinase 1 alters metabolic regulation in melanoma. Cancer Letters. PMID 28235541 DOI: 10.1016/J.Canlet.2017.02.013 |
0.414 |
|
2017 |
Wilking-Busch MJ, Ndiaye MA, Huang W, Ahmad N. Expression Profile of SIRT2 in Human Melanoma and Implications for Sirtuin-Based Chemotherapy. Cell Cycle (Georgetown, Tex.). 0. PMID 28166441 DOI: 10.1080/15384101.2017.1288323 |
0.426 |
|
2017 |
Garcia-Peterson L, Ndiaye MA, Singh CK, Huang W, Ahmad N. Abstract 820: Potential pro-proliferative role of SIRT6 in melanoma Cancer Research. 77: 820-820. DOI: 10.1158/1538-7445.Am2017-820 |
0.303 |
|
2017 |
Gutteridge RE, Singh CK, Ndiaye MA, Ahmad N. Abstract 5415: Targeted depletion of polo-like kinase 1 alters metabolic regulation in melanoma Cancer Research. 77: 5415-5415. DOI: 10.1158/1538-7445.Am2017-5415 |
0.319 |
|
2017 |
Singh CK, Ndiaye MA, Mintie CA, Chhabra G, Ahmad N. Abstract 5263: Chemopreventive effects of dietary grapes on skin cancer Cancer Research. 77: 5263-5263. DOI: 10.1158/1538-7445.Am2017-5263 |
0.408 |
|
2017 |
Singh CK, Malas KM, Tydrick C, Iczkowski KA, Ahmad N. Abstract 4139: Role of zinc transporters in prostate cancer and a potential association with racial disparity Cancer Research. 77: 4139-4139. DOI: 10.1158/1538-7445.Am2017-4139 |
0.428 |
|
2017 |
Chhabra G, Singh C, Ndiaye M, Fedorowicz S, Molot A, Ahmad N. LB995 Polo-like kinase 1 inhibition suppresses epithelial mesenchymal transition in melanoma Journal of Investigative Dermatology. 137: B11. DOI: 10.1016/J.Jid.2017.07.077 |
0.334 |
|
2017 |
Nihal M, Singh C, Wood G, Ahmad N. 126 Potential pro-proliferative role of polo-like kinase 4 in cutaneous T-cell lymphoma Journal of Investigative Dermatology. 137: S21. DOI: 10.1016/J.Jid.2017.02.140 |
0.33 |
|
2016 |
Singh CK, Malas KM, Tydrick C, Siddiqui IA, Iczkowski KA, Ahmad N. Analysis of Zinc-Exporters Expression in Prostate Cancer. Scientific Reports. 6: 36772. PMID 27833104 DOI: 10.1038/Srep36772 |
0.394 |
|
2016 |
Cholewa BD, Ndiaye MA, Huang W, Liu X, Ahmad N. Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo. Cancer Letters. PMID 27793694 DOI: 10.1016/J.Canlet.2016.10.025 |
0.427 |
|
2016 |
Chen L, Li J, Farah E, Sarkar S, Ahmad N, Gupta S, Larner J, Liu X. Co-targeting HSP90 and its client proteins for treatment of prostate cancer. Molecular Cancer Therapeutics. PMID 27390342 DOI: 10.1158/1535-7163.Mct-16-0241 |
0.458 |
|
2016 |
Gutteridge RE, Ndiaye MA, Liu X, Ahmad N. Plk1 Inhibitors in Cancer Therapy: From Laboratory to Clinics. Molecular Cancer Therapeutics. PMID 27330107 DOI: 10.1158/1535-7163.Mct-15-0897 |
0.482 |
|
2016 |
George J, Ahmad N. Mitochondrial Sirtuins in Cancer: Emerging Roles and Therapeutic Potential. Cancer Research. 76: 2500-6. PMID 27197261 DOI: 10.1158/0008-5472.Can-15-2733 |
0.467 |
|
2016 |
Chen L, Ahmad N, Liu X. Combining p53 stabilizers with metformin induces synergistic apoptosis through regulation of energy metabolism in castration-resistant prostate cancer. Cell Cycle (Georgetown, Tex.). 0. PMID 26900800 DOI: 10.1080/15384101.2016.1151582 |
0.466 |
|
2016 |
Li J, Wang R, Schweickert PG, Karki A, Yang Y, Kong Y, Ahmad N, Konieczny SF, Liu X. Plk1 Inhibition Enhances the Efficacy of Gemcitabine in Human Pancreatic Cancer. Cell Cycle (Georgetown, Tex.). 0. PMID 26890815 DOI: 10.1080/15384101.2016.1148838 |
0.47 |
|
2016 |
Singh CK, Siddiqui IA, El-Abd S, Mukhtar H, Ahmad N. Combination chemoprevention with grape antioxidants. Molecular Nutrition & Food Research. PMID 26829056 DOI: 10.1002/Mnfr.201500945 |
0.415 |
|
2016 |
Singh CK, Shabbir M, Nihal M, Iczkowski KA, Ahmad N. Abstract LB-228: Polo-like kinase 4: A potential new target for the management of prostate cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-228 |
0.565 |
|
2016 |
Shabbir M, Nihal M, Singh CK, Longley BJ, Ahmad N. Abstract LB-102: A pro-proliferative function of centriole duplication regulator, polo-like kinase-4 in human melanoma Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-102 |
0.529 |
|
2016 |
Singh CK, George J, Nihal M, Ahmad N. Abstract 3667: Potential role of DUSP4 as a tumor suppressor in pancreatic cancer Cancer Research. 76: 3667-3667. DOI: 10.1158/1538-7445.Am2016-3667 |
0.466 |
|
2016 |
George J, Nihal M, Ndiaye MA, Ahmad N. Abstract 1143: Pro-proliferative function of SIRT3 in a human melanoma xenograft mouse model Cancer Research. 76: 1143-1143. DOI: 10.1158/1538-7445.Am2016-1143 |
0.483 |
|
2016 |
Shabbir M, Nihal M, Singh C, Longley B, Ahmad N. 631 Potential pro-proliferative function of polo-like kinase 4 in human melanoma Journal of Investigative Dermatology. 136: S112. DOI: 10.1016/J.Jid.2016.02.672 |
0.326 |
|
2015 |
George J, Nihal M, Singh CK, Zhong W, Liu X, Ahmad N. Pro-proliferative function of mitochondrial sirtuin deacetylase SIRT3 in human melanoma. The Journal of Investigative Dermatology. PMID 26743598 DOI: 10.1016/J.Jid.2015.12.026 |
0.462 |
|
2015 |
Li J, Karki A, Hodges KB, Ahmad N, Zoubeidi A, Strebhardt K, Ratliff TL, Konieczny SF, Liu X. Co-targeting Polo-like kinase 1(Plk1) and the Wnt/β-catenin signaling pathway in castration-resistant prostate cancer. Molecular and Cellular Biology. PMID 26438599 DOI: 10.1128/Mcb.00825-15 |
0.428 |
|
2015 |
Li Z, Lu Y, Ahmad N, Strebhardt K, Liu X. Low-dose arsenic-mediated metabolic shift is associated with activation of Polo-like kinase 1 (Plk1). Cell Cycle (Georgetown, Tex.). 0. PMID 26292025 DOI: 10.1080/15384101.2015.1080397 |
0.385 |
|
2015 |
Siddiqui IA, Sanna V, Ahmad N, Sechi M, Mukhtar H. Resveratrol nanoformulation for cancer prevention and therapy. Annals of the New York Academy of Sciences. 1348: 20-31. PMID 26109073 DOI: 10.1111/Nyas.12811 |
0.433 |
|
2015 |
Posch C, Cholewa BD, Vujic I, Sanlorenzo M, Ma J, Kim ST, Kleffel S, Schatton T, Rappersberger K, Gutteridge R, Ahmad N, Ortiz-Urda S. Combined Inhibition of MEK and Plk1 Has Synergistic Antitumor Activity in NRAS Mutant Melanoma. The Journal of Investigative Dermatology. 135: 2475-83. PMID 26016894 DOI: 10.1038/Jid.2015.198 |
0.416 |
|
2015 |
Singh CK, Kaur S, George J, Nihal M, Pellitteri Hahn MC, Scarlett CO, Ahmad N. Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach. Oncotarget. 6: 10335-48. PMID 25929337 DOI: 10.18632/Oncotarget.3231 |
0.469 |
|
2015 |
Zhang Z, Chen L, Wang H, Ahmad N, Liu X. Inhibition of Plk1 represses androgen signaling pathway in castration-resistant prostate cancer. Cell Cycle (Georgetown, Tex.). 14: 2142-8. PMID 25927139 DOI: 10.1080/15384101.2015.1041689 |
0.493 |
|
2015 |
Chen L, Li Z, Ahmad N, Liu X. Plk1 phosphorylation of IRS2 prevents premature mitotic exit via AKT inactivation. Biochemistry. 54: 2473-80. PMID 25830382 DOI: 10.1021/Acs.Biochem.5B00016 |
0.326 |
|
2015 |
Shao C, Ahmad N, Hodges K, Kuang S, Ratliff T, Liu X. Inhibition of polo-like kinase 1 (Plk1) enhances the antineoplastic activity of metformin in prostate cancer. The Journal of Biological Chemistry. 290: 2024-33. PMID 25505174 DOI: 10.1074/Jbc.M114.596817 |
0.514 |
|
2015 |
Wilking MJ, Ahmad N. The Role of SIRT1 in Cancer: The Saga Continues American Journal of Pathology. 185: 26-28. PMID 25452121 DOI: 10.1016/J.Ajpath.2014.10.002 |
0.428 |
|
2015 |
Singh CK, Ndiaye MA, Ahmad N. Resveratrol and cancer: Challenges for clinical translation. Biochimica Et Biophysica Acta. 1852: 1178-1185. PMID 25446990 DOI: 10.1016/J.Bbadis.2014.11.004 |
0.349 |
|
2015 |
Singh CK, Nihal M, George J, Siddiqui IA, Mukhtar H, Ahmad N. Abstract 4643: Effect of resveratrol-zinc combination on prostate tumor growth in transgenic adenocarcinoma of mouse prostate (TRAMP) model Cancer Research. 75: 4643-4643. DOI: 10.1158/1538-7445.Am2015-4643 |
0.463 |
|
2015 |
Singh CK, Ahmad N. Abstract 2801: Resveratrol-Quercetin combination significantly inhibits prostate cancer in TRAMP mice Cancer Research. 75: 2801-2801. DOI: 10.1158/1538-7445.Am2015-2801 |
0.515 |
|
2015 |
George J, Nihal M, Singh CK, Ahmad N. Abstract 1127: Small molecule SIRT3 inhibitor 4′-bromo-resveratrol inhibits proliferation, promotes apoptosis and causes metabolic reprograming of human melanoma cells Cancer Research. 75: 1127-1127. DOI: 10.1158/1538-7445.Am2015-1127 |
0.488 |
|
2014 |
Wilking MJ, Singh CK, Nihal M, Ndiaye MA, Ahmad N. Sirtuin deacetylases: a new target for melanoma management. Cell Cycle (Georgetown, Tex.). 13: 2821-6. PMID 25486469 DOI: 10.4161/15384101.2014.949085 |
0.476 |
|
2014 |
Zhang Z, Hou X, Shao C, Li J, Cheng JX, Kuang S, Ahmad N, Ratliff T, Liu X. Plk1 inhibition enhances the efficacy of androgen signaling blockade in castration-resistant prostate cancer. Cancer Research. 74: 6635-47. PMID 25252916 DOI: 10.1158/0008-5472.Can-14-1916 |
0.482 |
|
2014 |
Li Z, Li J, Bi P, Lu Y, Burcham G, Elzey BD, Ratliff T, Konieczny SF, Ahmad N, Kuang S, Liu X. Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state. Molecular and Cellular Biology. 34: 3642-61. PMID 25047839 DOI: 10.1128/Mcb.00814-14 |
0.386 |
|
2014 |
Singh CK, Ndiaye MA, Siddiqui IA, Nihal M, Havighurst T, Kim K, Zhong W, Mukhtar H, Ahmad N. Methaneseleninic acid and γ-Tocopherol combination inhibits prostate tumor growth in Vivo in a xenograft mouse model. Oncotarget. 5: 3651-61. PMID 25004451 DOI: 10.18632/Oncotarget.1979 |
0.406 |
|
2014 |
Cholewa BD, Pellitteri-Hahn MC, Scarlett CO, Ahmad N. Large-scale label-free comparative proteomics analysis of polo-like kinase 1 inhibition via the small-molecule inhibitor BI 6727 (Volasertib) in BRAF(V600E) mutant melanoma cells. Journal of Proteome Research. 13: 5041-50. PMID 24884503 DOI: 10.1021/Pr5002516 |
0.465 |
|
2014 |
Singh CK, Pitschmann A, Ahmad N. Resveratrol-zinc combination for prostate cancer management. Cell Cycle (Georgetown, Tex.). 13: 1867-74. PMID 24866157 DOI: 10.4161/Cc.29334 |
0.473 |
|
2014 |
Wilking MJ, Singh C, Nihal M, Zhong W, Ahmad N. SIRT1 deacetylase is overexpressed in human melanoma and its small molecule inhibition imparts anti-proliferative response via p53 activation. Archives of Biochemistry and Biophysics. 563: 94-100. PMID 24751483 DOI: 10.1016/J.Abb.2014.04.001 |
0.455 |
|
2014 |
Singh CK, George J, Nihal M, Sabat G, Kumar R, Ahmad N. Novel downstream molecular targets of SIRT1 in melanoma: a quantitative proteomics approach. Oncotarget. 5: 1987-99. PMID 24743044 DOI: 10.18632/Oncotarget.1898 |
0.451 |
|
2014 |
Nihal M, Ahmad N, Wood GS. SIRT1 is upregulated in cutaneous T-cell lymphoma, and its inhibition induces growth arrest and apoptosis. Cell Cycle (Georgetown, Tex.). 13: 632-40. PMID 24343700 DOI: 10.4161/Cc.27523 |
0.406 |
|
2014 |
Ndiaye MA, Nihal M, Wood GS, Ahmad N. Skin, reactive oxygen species, and circadian clocks. Antioxidants & Redox Signaling. 20: 2982-96. PMID 24111846 DOI: 10.1089/Ars.2013.5645 |
0.3 |
|
2014 |
Cholewa BD, Hahn MP, Scarlett CO, Ahmad N. Abstract 4543: Identification of downstream targets of polo-like kinase 1 in melanoma by large-scale label-free comparative proteomics profiling Cancer Research. 74: 4543-4543. DOI: 10.1158/1538-7445.Am2014-4543 |
0.483 |
|
2014 |
Singh CK, Kaur S, George J, Pellitteri-Hahn MC, Scarlett CO, Ahmad N. Abstract 4533: Mechanism of anti-proliferative effects of sanguinarine in pancreatic cancer cells: A label-free quantitative proteomics approach Cancer Research. 74: 4533-4533. DOI: 10.1158/1538-7445.Am2014-4533 |
0.438 |
|
2014 |
George J, Nihal M, Singh CK, Zhong W, Ahmad N. Abstract 3516: The mitochondrial sirtuin SIRT3 promotes survival of human melanoma cells in vitro Cancer Research. 74: 3516-3516. DOI: 10.1158/1538-7445.Am2014-3516 |
0.494 |
|
2014 |
Singh CK, George J, Duster M, Safdar N, Ahmad N. Abstract 235: Combination of the probiotic Lactobacillus rhamnosus GG with grape antioxidant resveratrol for the management of colorectal cancer Cancer Research. 74: 235-235. DOI: 10.1158/1538-7445.Am2014-235 |
0.44 |
|
2013 |
Cholewa BD, Liu X, Ahmad N. The role of polo-like kinase 1 in carcinogenesis: cause or consequence? Cancer Research. 73: 6848-55. PMID 24265276 DOI: 10.1158/0008-5472.CAN-13-2197 |
0.336 |
|
2013 |
Singh CK, George J, Ahmad N. Resveratrol-based combinatorial strategies for cancer management. Annals of the New York Academy of Sciences. 1290: 113-21. PMID 23855473 DOI: 10.1111/Nyas.12160 |
0.418 |
|
2013 |
Ahmad N, Mukhtar H. Antioxidants meet molecular targets for cancer prevention and therapeutics. Antioxidants & Redox Signaling. 19: 85-8. PMID 23521502 DOI: 10.1089/Ars.2013.5299 |
0.376 |
|
2013 |
Wilking M, Ndiaye M, Mukhtar H, Ahmad N. Circadian rhythm connections to oxidative stress: Implications for human health Antioxidants and Redox Signaling. 19: 192-208. PMID 23198849 DOI: 10.1089/Ars.2012.4889 |
0.311 |
|
2013 |
George J, Nihal M, Singh CK, Ahmad N. Abstract LB-209: SIRT3, a mitochondrial sirtuin deacetylase, promotes survival of human melanoma cells. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-209 |
0.512 |
|
2013 |
Singh CK, Ndiaye MA, Siddiqui IA, Nihal M, Havighurst T, Zhong W, Mukhtar H, Ahmad N. Abstract 3693: Methaneseleninic acid and γ-tocopherol combination inhibits prostate tumor growth in a xenograft model . Cancer Research. 73: 3693-3693. DOI: 10.1158/1538-7445.Am2013-3693 |
0.429 |
|
2013 |
Singh CK, George J, Kumar R, Ahmad N. Abstract 2509: Mechanism of anti-proliferative effects of SIRT1 inhibition in melanoma cells: a proteomics approach. Cancer Research. 73: 2509-2509. DOI: 10.1158/1538-7445.Am2013-2509 |
0.429 |
|
2012 |
Schmit TL, Nihal M, Ndiaye M, Setaluri V, Spiegelman VS, Ahmad N. Numb regulates stability and localization of the mitotic kinase PLK1 and is required for transit through mitosis. Cancer Research. 72: 3864-72. PMID 22593191 DOI: 10.1158/0008-5472.Can-12-0714 |
0.808 |
|
2012 |
Desotelle JA, Wilking MJ, Ahmad N. The circadian control of skin and cutaneous photodamage Photochemistry and Photobiology. 88: 1037-1047. PMID 22277067 DOI: 10.1111/J.1751-1097.2012.01099.X |
0.347 |
|
2012 |
Challa A, Ahmad N, Mukhtar H. Cancer prevention through sensible nutrition (commentary). International Journal of Oncology. 11: 1387-92. PMID 21528350 DOI: 10.3892/Ijo.11.6.1387 |
0.397 |
|
2012 |
Singh CK, Wilking MJ, Nihal M, Ahmad N. Abstract 4722: Targeted inhibition of SIRT1 histone deacetylase by small-molecule inhibitor Tenovin-1 imparts significant anti-proliferative effects in human melanoma cells Cancer Research. 72: 4722-4722. DOI: 10.1158/1538-7445.Am2012-4722 |
0.519 |
|
2012 |
Singh CK, Nihal M, Ahmad N. Abstract 3729: Resveratrol enhances the anti-proliferative response of zinc by increasing zinc-transporter protein ZIP1 in prostate cancer cells: A novel combinatorial approach for prostate cancer management Cancer Research. 72: 3729-3729. DOI: 10.1158/1538-7445.Am2012-3729 |
0.506 |
|
2012 |
Cholewa BD, Desotelle JA, Ahmad N. Abstract 1920: Small molecule inhibitor of polo-like kinase 1 (Plk1) causes significant melanoma growth delay and regressionin vivo Cancer Research. 72: 1920-1920. DOI: 10.1158/1538-7445.Am2012-1920 |
0.476 |
|
2011 |
Liu XS, Song B, Elzey BD, Ratliff TL, Konieczny SF, Cheng L, Ahmad N, Liu X. Polo-like kinase 1 facilitates loss of Pten tumor suppressor-induced prostate cancer formation. The Journal of Biological Chemistry. 286: 35795-800. PMID 21890624 DOI: 10.1074/Jbc.C111.269050 |
0.516 |
|
2011 |
Johnson JJ, Nihal M, Siddiqui IA, Scarlett CO, Bailey HH, Mukhtar H, Ahmad N. Enhancing the bioavailability of resveratrol by combining it with piperine. Molecular Nutrition & Food Research. 55: 1169-76. PMID 21714124 DOI: 10.1002/Mnfr.201100117 |
0.314 |
|
2011 |
Nihal M, Stutz N, Schmit T, Ahmad N, Wood GS. Polo-like kinase 1 (Plk1) is expressed by cutaneous T-cell lymphomas (CTCLs), and its downregulation promotes cell cycle arrest and apoptosis. Cell Cycle (Georgetown, Tex.). 10: 1303-11. PMID 21436619 DOI: 10.4161/Cc.10.8.15353 |
0.807 |
|
2011 |
Ndiaye M, Kumar R, Ahmad N. Resveratrol in cancer management: where are we and where we go from here? Annals of the New York Academy of Sciences. 1215: 144-9. PMID 21261653 DOI: 10.1111/J.1749-6632.2010.05851.X |
0.405 |
|
2011 |
Ndiaye M, Philippe C, Mukhtar H, Ahmad N. The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges. Archives of Biochemistry and Biophysics. 508: 164-70. PMID 21215251 DOI: 10.1016/J.Abb.2010.12.030 |
0.335 |
|
2011 |
Jung-Hynes B, Schmit TL, Reagan-Shaw SR, Siddiqui IA, Mukhtar H, Ahmad N. Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model. Journal of Pineal Research. 50: 140-9. PMID 21062352 DOI: 10.1111/J.1600-079X.2010.00823.X |
0.806 |
|
2011 |
Ahmad N, Kumar R. Steroid hormone receptors in cancer development: a target for cancer therapeutics. Cancer Letters. 300: 1-9. PMID 20926181 DOI: 10.1016/J.Canlet.2010.09.008 |
0.466 |
|
2011 |
Ledesma MC, Jung-Hynes B, Schmit TL, Kumar R, Mukhtar H, Ahmad N. Selenium and vitamin E for prostate cancer: post-SELECT (Selenium and Vitamin E Cancer Prevention Trial) status. Molecular Medicine (Cambridge, Mass.). 17: 134-43. PMID 20882260 DOI: 10.2119/Molmed.2010.00136 |
0.764 |
|
2011 |
Khan SH, Arnott JA, Atamna H, Ahmad N, Kumar R. Abstract 4552: Naturally occurring osmolyte, trehalose induces a functionally active conformation in an intrinsically disordered transactivation function domain (AF1) of the Glucocorticoid Receptor Cancer Research. 71: 4552-4552. DOI: 10.1158/1538-7445.Am2011-4552 |
0.332 |
|
2011 |
Nihal M, Ndiaye M, Wood GS, Ahmad N. Abstract 1647: Role of Sirt1 histone deacetylase in melanoma: A target for melanoma management via its inhibition Cancer Research. 71: 1647-1647. DOI: 10.1158/1538-7445.Am2011-1647 |
0.326 |
|
2010 |
Khan SH, Ahmad N, Ahmad F, Kumar R. Naturally occurring organic osmolytes: from cell physiology to disease prevention. Iubmb Life. 62: 891-5. PMID 21190292 DOI: 10.1002/Iub.406 |
0.31 |
|
2010 |
Siddiqui IA, Adhami VM, Ahmad N, Mukhtar H. Nanochemoprevention: sustained release of bioactive food components for cancer prevention. Nutrition and Cancer. 62: 883-90. PMID 20924964 DOI: 10.1080/01635581.2010.509537 |
0.398 |
|
2010 |
Jung-Hynes B, Huang W, Reiter RJ, Ahmad N. Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells. Journal of Pineal Research. 49: 60-8. PMID 20524973 DOI: 10.1111/J.1600-079X.2010.00767.X |
0.822 |
|
2010 |
Reagan-Shaw S, Eggert D, Mukhtar H, Ahmad N. Antiproliferative effects of apple peel extract against cancer cells. Nutrition and Cancer. 62: 517-24. PMID 20432173 DOI: 10.1080/01635580903441253 |
0.516 |
|
2010 |
Schmit TL, Ledesma MC, Ahmad N. Modulating polo-like kinase 1 as a means for cancer chemoprevention. Pharmaceutical Research. 27: 989-98. PMID 20107874 DOI: 10.1007/S11095-010-0051-8 |
0.809 |
|
2010 |
Jung-Hynes B, Reiter RJ, Ahmad N. Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer. Journal of Pineal Research. 48: 9-19. PMID 20025641 DOI: 10.1111/J.1600-079X.2009.00729.X |
0.797 |
|
2010 |
Jung BD, Huang W, Ahmad N. Abstract LB-16: Altered circadian rhythm components are resynchronized by melatonin in human prostate cancer Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-16 |
0.518 |
|
2010 |
Jung-Hynes BD, Schmit TL, Reagan-Shaw S, Siddiqui IA, Mukhtar H, Ahmad N. Abstract 5478: Melatonin, a novel Sirt1 inhibitor, imparts anti-proliferative effects against PCain vitroin cell culture andin vivoin transgenic adenocarcinoma of mouse prostate (TRAMP) model Cancer Research. 70: 5478-5478. DOI: 10.1158/1538-7445.Am10-5478 |
0.81 |
|
2010 |
Schmit TL, Setaluri V, Spiegelman VS, Ahmad N. Abstract 1064: Numb, a progenitor cell fate determinant and intrinsic inhibitor of Notch signaling, is cell cycle regulated and required for proper mitotic entry and progression in melanoma cells Cellular and Molecular Biology. 70: 1064-1064. DOI: 10.1158/1538-7445.Am10-1064 |
0.786 |
|
2010 |
Schmit TL, Setaluri V, Spiegelman VS, Ahmad N. Abstract 1062: Numb, an intrinsic Notch inhibitor, possesses a tumor suppressor role through regulation of Plk1 localization during mitosis Cancer Research. 70: 1062-1062. DOI: 10.1158/1538-7445.Am10-1062 |
0.794 |
|
2009 |
Schmit TL, Zhong W, Nihal M, Ahmad N. Polo-like kinase 1 (Plk1) in non-melanoma skin cancers. Cell Cycle (Georgetown, Tex.). 8: 2697-702. PMID 19652546 DOI: 10.4161/Cc.8.17.9413 |
0.826 |
|
2009 |
Schmit TL, Zhong W, Setaluri V, Spiegelman VS, Ahmad N. Targeted depletion of Polo-like kinase (Plk) 1 through lentiviral shRNA or a small-molecule inhibitor causes mitotic catastrophe and induction of apoptosis in human melanoma cells. The Journal of Investigative Dermatology. 129: 2843-53. PMID 19554017 DOI: 10.1038/Jid.2009.172 |
0.821 |
|
2009 |
Nihal M, Ahsan H, Siddiqui IA, Mukhtar H, Ahmad N, Wood GS. (-)-Epigallocatechin-3-gallate (EGCG) sensitizes melanoma cells to interferon induced growth inhibition in a mouse model of human melanoma. Cell Cycle (Georgetown, Tex.). 8: 2057-63. PMID 19502799 DOI: 10.4161/Cc.8.13.8862 |
0.426 |
|
2009 |
Jung-Hynes B, Ahmad N. SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age-related neoplasms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2803-9. PMID 19439501 DOI: 10.1096/Fj.09-129148 |
0.812 |
|
2009 |
Jung-Hynes B, Ahmad N. Role of p53 in the anti-proliferative effects of Sirt1 inhibition in prostate cancer cells. Cell Cycle (Georgetown, Tex.). 8: 1478-83. PMID 19377286 DOI: 10.4161/Cc.8.10.8408 |
0.822 |
|
2009 |
Adhami VM, Siddiqui IA, Sarfaraz S, Khwaja SI, Hafeez BB, Ahmad N, Mukhtar H. Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 1947-53. PMID 19276266 DOI: 10.1158/1078-0432.Ccr-08-2332 |
0.449 |
|
2009 |
Siddiqui IA, Adhami VM, Bharali DJ, Hafeez BB, Asim M, Khwaja SI, Ahmad N, Cui H, Mousa SA, Mukhtar H. Introducing nanochemoprevention as a novel approach for cancer control: proof of principle with green tea polyphenol epigallocatechin-3-gallate. Cancer Research. 69: 1712-6. PMID 19223530 DOI: 10.1158/0008-5472.Can-08-3978 |
0.364 |
|
2009 |
Jung-Hynes B, Nihal M, Zhong W, Ahmad N. Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition? The Journal of Biological Chemistry. 284: 3823-32. PMID 19075016 DOI: 10.1074/Jbc.M807869200 |
0.826 |
|
2008 |
Reagan-Shaw S, Nihal M, Ahsan H, Mukhtar H, Ahmad N. Combination of vitamin E and selenium causes an induction of apoptosis of human prostate cancer cells by enhancing Bax/Bcl-2 ratio Prostate. 68: 1624-1634. PMID 18668529 DOI: 10.1002/Pros.20824 |
0.469 |
|
2008 |
Reagan-Shaw S, Mukhtar H, Ahmad N. Resveratrol imparts photoprotection of normal cells and enhances the efficacy of radiation therapy in cancer cells. Photochemistry and Photobiology. 84: 415-21. PMID 18221451 DOI: 10.1111/J.1751-1097.2007.00279.X |
0.416 |
|
2007 |
Thiyagarajan S, Bhatia N, Reagan-Shaw S, Cozma D, Thomas-Tikhonenko A, Ahmad N, Spiegelman VS. Role of GLI2 transcription factor in growth and tumorigenicity of prostate cells. Cancer Research. 67: 10642-6. PMID 18006803 DOI: 10.1158/0008-5472.Can-07-2015 |
0.514 |
|
2007 |
Ahsan H, Reagan-Shaw S, Eggert DM, Tan TC, Afaq F, Mukhtar H, Ahmad N. Protective effect of sanguinarine on ultraviolet B-mediated damages in SKH-1 hairless mouse skin: implications for prevention of skin cancer. Photochemistry and Photobiology. 83: 986-93. PMID 17645675 DOI: 10.1111/J.1751-1097.2007.00156.X |
0.419 |
|
2007 |
Schmit TL, Ahmad N. Regulation of mitosis via mitotic kinases: new opportunities for cancer management. Molecular Cancer Therapeutics. 6: 1920-31. PMID 17620424 DOI: 10.1158/1535-7163.Mct-06-0781 |
0.795 |
|
2007 |
Reagan-Shaw S, Ahmad N. The role of Forkhead-box Class O (FoxO) transcription factors in cancer: a target for the management of cancer. Toxicology and Applied Pharmacology. 224: 360-8. PMID 17275054 DOI: 10.1016/J.Taap.2006.12.003 |
0.479 |
|
2007 |
Ahsan H, Reagan-Shaw S, Breur J, Ahmad N. Sanguinarine induces apoptosis of human pancreatic carcinoma AsPC-1 and BxPC-3 cells via modulations in Bcl-2 family proteins Cancer Letters. 249: 198-208. PMID 17005319 DOI: 10.1016/J.Canlet.2006.08.018 |
0.466 |
|
2006 |
Jung B, Ahmad N. Melatonin in cancer management: Progress and promise Cancer Research. 66: 9789-9793. PMID 17047036 DOI: 10.1158/0008-5472.CAN-06-1776 |
0.338 |
|
2006 |
Aziz MH, Nihal M, Fu VX, Jarrard DF, Ahmad N. Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3'-kinase/Akt pathway and Bcl-2 family proteins. Molecular Cancer Therapeutics. 5: 1335-41. PMID 16731767 DOI: 10.1158/1535-7163.Mct-05-0526 |
0.525 |
|
2006 |
Khan N, Afaq F, Saleem M, Ahmad N, Mukhtar H. Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. Cancer Research. 66: 2500-5. PMID 16510563 DOI: 10.1158/0008-5472.Can-05-3636 |
0.462 |
|
2006 |
Reagan-Shaw S, Breur J, Ahmad N. Enhancement of UVB radiation-mediated apoptosis by sanguinarine in HaCaT human immortalized keratinocytes. Molecular Cancer Therapeutics. 5: 418-29. PMID 16505117 DOI: 10.1158/1535-7163.Mct-05-0250 |
0.425 |
|
2006 |
Reagan-Shaw S, Ahmad N. RNA interference-mediated depletion of phosphoinositide 3-kinase activates forkhead box class O transcription factors and induces cell cycle arrest and apoptosis in breast carcinoma cells. Cancer Research. 66: 1062-9. PMID 16424042 DOI: 10.1158/0008-5472.Can-05-1018 |
0.435 |
|
2006 |
Siddiqui IA, Zaman N, Aziz MH, Reagan-Shaw SR, Sarfaraz S, Adhami VM, Ahmad N, Raisuddin S, Mukhtar H. Inhibition of CWR22Rν1 tumor growth and PSA secretion in athymic nude mice by green and black teas Carcinogenesis. 27: 833-839. PMID 16387739 DOI: 10.1093/Carcin/Bgi323 |
0.485 |
|
2005 |
Reagan-Shaw S, Ahmad N. Polo-like kinase (Plk) 1 as a target for prostate cancer management. Iubmb Life. 57: 677-82. PMID 16223707 DOI: 10.1080/15216540500305910 |
0.522 |
|
2005 |
Ahsan H, Aziz MH, Ahmad N. Ultraviolet B exposure activates Stat3 signaling via phosphorylation at tyrosine705 in skin of SKH1 hairless mouse: A target for the management of skin cancer? Biochemical and Biophysical Research Communications. 333: 241-246. PMID 15936723 DOI: 10.1016/J.Bbrc.2005.05.106 |
0.395 |
|
2005 |
Aziz MH, Reagan-Shaw S, Wu J, Longley BJ, Ahmad N. Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1193-5. PMID 15837718 DOI: 10.1096/Fj.04-3582Fje |
0.446 |
|
2005 |
Saleem M, Adhami VM, Ahmad N, Gupta S, Mukhtar H. Prognostic significance of metastasis-associated protein S100A4 (Mts1) in prostate cancer progression and chemoprevention regimens in an autochthonous mouse model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 147-53. PMID 15671539 |
0.372 |
|
2005 |
Reagan-Shaw S, Ahmad N. Silencing of polo-like kinase (Plk) 1 via siRNA causes induction of apoptosis and impairment of mitosis machinery in human prostate cancer cells: implications for the treatment of prostate cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 611-3. PMID 15661849 DOI: 10.1096/Fj.04-2910Fje |
0.562 |
|
2005 |
Nihal M, Ahmad N, Mukhtar H, Wood GS. Anti-proliferative and proapoptotic effects of (-)-epigallocatechin-3-gallate on human melanoma: possible implications for the chemoprevention of melanoma. International Journal of Cancer. Journal International Du Cancer. 114: 513-21. PMID 15609335 DOI: 10.1002/Ijc.20785 |
0.508 |
|
2005 |
Aziz MH, Afaq F, Ahmad N. Prevention of ultraviolet-B radiation damage by resveratrol in mouse skin is mediated via modulation in survivin. Photochemistry and Photobiology. 81: 25-31. PMID 15469386 DOI: 10.1562/2004-08-13-Ra-274.1 |
0.392 |
|
2004 |
Aziz MH, Ghotra AS, Shukla Y, Ahmad N. Ultraviolet-B radiation causes an upregulation of survivin in human keratinocytes and mouse skin. Photochemistry and Photobiology. 80: 602-8. PMID 15623349 DOI: 10.1562/0031-8655(2004)080<0602:Urcauo>2.0.Co;2 |
0.395 |
|
2004 |
Adhami VM, Siddiqui IA, Ahmad N, Gupta S, Mukhtar H. Oral consumption of green tea polyphenols inhibits insulin-like growth factor-I-induced signaling in an autochthonous mouse model of prostate cancer. Cancer Research. 64: 8715-22. PMID 15574782 DOI: 10.1158/0008-5472.Can-04-2840 |
0.498 |
|
2004 |
Adhami VM, Aziz MH, Reagan-Shaw SR, Nihal M, Mukhtar H, Ahmad N. Sanguinarine causes cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin-dependent kinase machinery. Molecular Cancer Therapeutics. 3: 933-40. PMID 15299076 |
0.464 |
|
2004 |
Siddiqui IA, Afaq F, Adhami VM, Ahmad N, Mukhtar H. Antioxidants of the beverage tea in promotion of human health. Antioxidants & Redox Signaling. 6: 571-82. PMID 15130283 DOI: 10.1089/152308604773934323 |
0.362 |
|
2004 |
Reagan-Shaw S, Afaq F, Aziz MH, Ahmad N. Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin. Oncogene. 23: 5151-60. PMID 15122319 DOI: 10.1038/Sj.Onc.1207666 |
0.464 |
|
2004 |
Siddiqui IA, Adhami VM, Afaq F, Ahmad N, Mukhtar H. Modulation of phosphatidylinositol-3-kinase/protein kinase B- and mitogen-activated protein kinase-pathways by tea polyphenols in human prostate cancer cells. Journal of Cellular Biochemistry. 91: 232-42. PMID 14743383 DOI: 10.1002/Jcb.10737 |
0.52 |
|
2004 |
Ahmad N. Polo-like kinase (Plk) 1: A novel target for the treatment of prostate cancer Faseb Journal. 18: 5-7. PMID 14718382 DOI: 10.1096/Fj.03-0848Hyp |
0.547 |
|
2004 |
Gupta S, Hastak K, Afaq F, Ahmad N, Mukhtar H. Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis. Oncogene. 23: 2507-22. PMID 14676829 DOI: 10.1038/Sj.Onc.1207353 |
0.4 |
|
2003 |
Afaq F, Ahmad N, Mukhtar H. Suppression of UVB-induced phosphorylation of mitogen-activated protein kinases and nuclear factor kappa B by green tea polyphenol in SKH-1 hairless mice. Oncogene. 22: 9254-64. PMID 14681684 DOI: 10.1038/Sj.Onc.1207035 |
0.376 |
|
2003 |
Hastak K, Gupta S, Ahmad N, Agarwal MK, Agarwal ML, Mukhtar H. Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells. Oncogene. 22: 4851-9. PMID 12894226 DOI: 10.1038/Sj.Onc.1206708 |
0.462 |
|
2003 |
Adhami VM, Ahmad N, Mukhtar H. Molecular targets for green tea in prostate cancer prevention. The Journal of Nutrition. 133: 2417S-2424S. PMID 12840218 DOI: 10.1093/Jn/133.7.2417S |
0.534 |
|
2003 |
Aziz MH, Kumar R, Ahmad N. Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review). International Journal of Oncology. 23: 17-28. PMID 12792772 DOI: 10.3892/Ijo.23.1.17 |
0.474 |
|
2003 |
Adhami VM, Afaq F, Ahmad N. Suppression of ultraviolet B exposure-mediated activation of NF-kappaB in normal human keratinocytes by resveratrol. Neoplasia (New York, N.Y.). 5: 74-82. PMID 12659672 DOI: 10.1016/S1476-5586(03)80019-2 |
0.413 |
|
2003 |
Afaq F, Adhami VM, Ahmad N, Mukhtar H. Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea Constituent (-)-epigallocatechin-3-gallate. Oncogene. 22: 1035-44. PMID 12592390 DOI: 10.1038/Sj.Onc.1206206 |
0.429 |
|
2003 |
Afaq F, Adhami VM, Ahmad N. Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice. Toxicology and Applied Pharmacology. 186: 28-37. PMID 12583990 DOI: 10.1016/S0041-008X(02)00014-5 |
0.407 |
|
2002 |
Afaq F, Adhami VM, Ahmad N, Mukhtar H. Botanical antioxidants for chemoprevention of photocarcinogenesis. Frontiers in Bioscience : a Journal and Virtual Library. 7: d784-92. PMID 11897547 DOI: 10.2741/Afaq |
0.402 |
|
2002 |
Ahmad N, Adhami VM, Gupta S, Cheng P, Mukhtar H. Role of the retinoblastoma (pRb)-E2F/DP pathway in cancer chemopreventive effects of green tea polyphenol epigallocatechin-3-gallate. Archives of Biochemistry and Biophysics. 398: 125-31. PMID 11811957 DOI: 10.1006/Abbi.2001.2704 |
0.462 |
|
2001 |
Adhami VM, Afaq F, Ahmad N. Involvement of the retinoblastoma (pRb)-E2F/DP pathway during antiproliferative effects of resveratrol in human epidermoid carcinoma (A431) cells. Biochemical and Biophysical Research Communications. 288: 579-85. PMID 11676482 DOI: 10.1006/Bbrc.2001.5819 |
0.484 |
|
2001 |
Ahmad N, Gilliam AC, Katiyar SK, O'Brien TG, Mukhtar H. A definitive role of ornithine decarboxylase in photocarcinogenesis. The American Journal of Pathology. 159: 885-92. PMID 11549581 DOI: 10.1016/S0002-9440(10)61764-6 |
0.343 |
|
2001 |
Gupta S, Hastak K, Ahmad N, Lewin JS, Mukhtar H. Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols. Proceedings of the National Academy of Sciences of the United States of America. 98: 10350-5. PMID 11504910 DOI: 10.1073/Pnas.171326098 |
0.467 |
|
2001 |
Ahmad N, Kalka K, Mukhtar H. In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy. Oncogene. 20: 2314-7. PMID 11402326 DOI: 10.1038/Sj.Onc.1204313 |
0.434 |
|
2001 |
Ahmad N, Mukhtar H. Cutaneous photochemoprotection by green tea: a brief review. Skin Pharmacology and Applied Skin Physiology. 14: 69-76. PMID 11316965 DOI: 10.1159/000056336 |
0.444 |
|
2001 |
Srivastava M, Ahmad N, Gupta S, Mukhtar H. Involvement of Bcl-2 and Bax in photodynamic therapy-mediated apoptosis. Antisense Bcl-2 oligonucleotide sensitizes RIF 1 cells to photodynamic therapy apoptosis. The Journal of Biological Chemistry. 276: 15481-8. PMID 11278320 DOI: 10.1074/Jbc.M006920200 |
0.377 |
|
2001 |
Gupta S, Srivastava M, Ahmad N, Sakamoto K, Bostwick DG, Mukhtar H. Lipoxygenase-5 is overexpressed in prostate adenocarcinoma. Cancer. 91: 737-43. PMID 11241241 DOI: 10.1002/1097-0142(20010215)91:4<737::Aid-Cncr1059>3.0.Co;2-F |
0.401 |
|
2001 |
Ahmad N, Katiyar SK, Mukhtar H. Antioxidants in chemoprevention of skin cancer. Current Problems in Dermatology. 29: 128-39. PMID 11225193 DOI: 10.1159/000060662 |
0.406 |
|
2001 |
Azizuddin K, Kalka K, Chiu SM, Ahmad N, Mukhtar H, Separovic D. Recombinant human tumor necrosis factor alpha does not potentiate cell killing after photodynamic therapy with a silicon phthalocyanine in A431 human epidermoid carcinoma cells. International Journal of Oncology. 18: 411-5. PMID 11172611 DOI: 10.3892/Ijo.18.2.411 |
0.44 |
|
2001 |
Ahmad N, Gupta S, Feyes DK, Mukhtar H. Involvement of Fas (APO-1/CD-95) during photodynamic-therapy-mediated apoptosis in human epidermoid carcinoma A431 cells. The Journal of Investigative Dermatology. 115: 1041-6. PMID 11121139 DOI: 10.1046/J.1523-1747.2000.00147.X |
0.348 |
|
2000 |
Athar M, Kim AL, Ahmad N, Mukhtar H, Gautier J, Bickers DR. Mechanism of ultraviolet B-induced cell cycle arrest in G2/M phase in immortalized skin keratinocytes with defective p53. Biochemical and Biophysical Research Communications. 277: 107-11. PMID 11027648 DOI: 10.1006/Bbrc.2000.3436 |
0.392 |
|
2000 |
Ahmad N, Cheng P, Mukhtar H. Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate. Biochemical and Biophysical Research Communications. 275: 328-34. PMID 10964666 DOI: 10.1006/Bbrc.2000.3297 |
0.471 |
|
2000 |
Ahmad N, Mukhtar H. Mechanism of photodynamic therapy-induced cell death. Methods in Enzymology. 319: 342-58. PMID 10907525 DOI: 10.1016/S0076-6879(00)19034-2 |
0.381 |
|
2000 |
Mukhtar H, Ahmad N. Tea polyphenols: prevention of cancer and optimizing health. The American Journal of Clinical Nutrition. 71: 1698S-702S; discussi. PMID 10837321 DOI: 10.1093/Ajcn/71.6.1698S |
0.396 |
|
2000 |
Ahmad N, Gupta S, Mukhtar H. Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kappaB in cancer cells versus normal cells. Archives of Biochemistry and Biophysics. 376: 338-46. PMID 10775421 DOI: 10.1006/Abbi.2000.1742 |
0.466 |
|
2000 |
Gupta S, Ahmad N, Nieminen AL, Mukhtar H. Growth inhibition, cell-cycle dysregulation, and induction of apoptosis by green tea constituent (-)-epigallocatechin-3-gallate in androgen-sensitive and androgen-insensitive human prostate carcinoma cells. Toxicology and Applied Pharmacology. 164: 82-90. PMID 10739747 DOI: 10.1006/Taap.1999.8885 |
0.51 |
|
2000 |
Chiu SM, Davis TW, Meyers M, Ahmad N, Mukhtar H, Separovic D. Phthalocyanine 4-photodynamic therapy induces ceramide generation and apoptosis in acid sphingomyelinase-deficient mouse embryonic fibroblasts. International Journal of Oncology. 16: 423-7. PMID 10639587 DOI: 10.3892/Ijo.16.2.423 |
0.36 |
|
2000 |
Gupta S, Srivastava M, Ahmad N, Bostwick DG, Mukhtar H. Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma. The Prostate. 42: 73-8. PMID 10579801 DOI: 10.1002/(Sici)1097-0045(20000101)42:1<73::Aid-Pros9>3.0.Co;2-G |
0.464 |
|
1999 |
Mukhtar H, Ahmad N. Cancer chemoprevention: Future holds in multiple agents Toxicology and Applied Pharmacology. 158: 207-210. PMID 10438653 DOI: 10.1006/Taap.1999.8721 |
0.401 |
|
1999 |
Balasubramanian S, Ahmad N, Mukhtar H. Upregulation of E2F transcription factors in chemically induced mouse skin tumors. International Journal of Oncology. 15: 387-90. PMID 10402252 DOI: 10.3892/Ijo.15.2.387 |
0.389 |
|
1999 |
Mukhtar H, Ahmad N. Mechanism of cancer chemopreventive activity of green Tea. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 220: 234-8. PMID 10202395 DOI: 10.1046/J.1525-1373.1999.D01-40.X |
0.417 |
|
1999 |
Ahmad N, Mukhtar H. Green tea polyphenols and cancer: biologic mechanisms and practical implications. Nutrition Reviews. 57: 78-83. PMID 10101921 DOI: 10.1111/J.1753-4887.1999.Tb06927.X |
0.421 |
|
1999 |
Ahmad N, Gupta S, Mukhtar H. Involvement of retinoblastoma (Rb) and E2F transcription factors during photodynamic therapy of human epidermoid carcinoma cells A431. Oncogene. 18: 1891-6. PMID 10086343 DOI: 10.1038/Sj.Onc.1202493 |
0.464 |
|
1999 |
Balasubramanian S, Kim KH, Ahmad N, Mukhtar H. Activation of telomerase and its association with G1-phase of the cell cycle during UVB-induced skin tumorigenesis in SKH-1 hairless mouse. Oncogene. 18: 1297-302. PMID 10022811 DOI: 10.1038/Sj.Onc.1202417 |
0.454 |
|
1998 |
Ahmad N, Gali H, Javed S, Agarwal R. Skin cancer chemopreventive effects of a flavonoid antioxidant silymarin are mediated via impairment of receptor tyrosine kinase signaling and perturbation in cell cycle progression. Biochemical and Biophysical Research Communications. 247: 294-301. PMID 9642119 DOI: 10.1006/Bbrc.1998.8748 |
0.457 |
|
1998 |
Ahmad N, Feyes DK, Agarwal R, Mukhtar H. Photodynamic therapy results in induction of WAF1/CIP1/P21 leading to cell cycle arrest and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 95: 6977-82. PMID 9618524 DOI: 10.1073/Pnas.95.12.6977 |
0.411 |
|
1998 |
Balasubramanian S, Ahmad N, Jeedigunta S, Mukhtar H. Alterations in cell cycle regulation in mouse skin tumors Biochemical and Biophysical Research Communications. 243: 744-748. PMID 9500999 DOI: 10.1006/Bbrc.1998.8172 |
0.448 |
|
1998 |
Ahmad N, Feyes DK, Nieminen AL, Agarwal R, Mukhtar H. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. Journal of the National Cancer Institute. 89: 1881-6. PMID 9414176 DOI: 10.1093/Jnci/89.24.1881 |
0.468 |
|
1998 |
Mukhtar H, Grupta S, Ahmad N. Inhibition of nuclear transcription factor NFκB by green tea constituent epigallocatechin-3-gallate in human epidermoid carcinoma cells A431 Journal of Dermatological Science. 16: S50. DOI: 10.1016/S0923-1811(98)83294-5 |
0.325 |
|
1997 |
Ahmad N, Srivastava RC, Agarwal R, Mukhtar H. Nitric oxide synthase and skin tumor promotion. Biochemical and Biophysical Research Communications. 232: 328-31. PMID 9125174 DOI: 10.1006/Bbrc.1997.6275 |
0.315 |
|
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