Guangwei Du - Publications

Affiliations: 
Molecular and Cellular Pharmacology Stony Brook University, Stony Brook, NY, United States 
Area:
Pharmacology, Cell Biology, Molecular Biology

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ishihara S, Sato T, Du G, Guardavaccaro D, Nakajima A, Sawai S, Kataoka T, Katagiri K. Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking. Bmc Biology. 18: 75. PMID 32600317 DOI: 10.1186/S12915-020-00809-0  0.345
2020 Symons JL, Cho KJ, Chang JT, Du G, Waxham MN, Hancock JF, Levental I, Levental KR. Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture conditions, subcellular membranes, and cell lineages. Soft Matter. PMID 32451522 DOI: 10.1039/D0Sm00404A  0.376
2020 Fu P, Ramchandran R, Shaaya M, Huang L, Ebenezer DL, Jiang Y, Komarova Y, Vogel SM, Malik AB, Minshall RD, Du G, Tonks NK, Natarajan V. Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation. The Journal of Biological Chemistry. PMID 32327488 DOI: 10.1074/Jbc.Ra119.011801  0.354
2020 Zheng L, Du G. Illustrating human PLD. Nature Chemical Biology. 16: 364-365. PMID 32198491 DOI: 10.1038/S41589-020-0503-3  0.37
2020 Momoi Y, Nishikimi A, Du G, Kataoka T, Katagiri K. Phosphatidic acid regulates subcellular distribution of RA-GEFs critical for chemokine-dependent migration. Biochemical and Biophysical Research Communications. PMID 31996307 DOI: 10.1016/J.Bbrc.2020.01.080  0.355
2019 Xiong J, He J, Xie WP, Hinojosa E, Ambati CSR, Putluri N, Kim HE, Zhu MX, Du G. Rapid affinity purification of intracellular organelles using twin strep tag. Journal of Cell Science. PMID 31780580 DOI: 10.1242/Jcs.235390  0.339
2019 Bolomini-Vittori M, Mennens SFB, Joosten B, Fransen J, Du G, van den Dries K, Cambi A. PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation. Scientific Reports. 9: 3556. PMID 30837487 DOI: 10.1038/S41598-019-39358-0  0.445
2019 Wang Z, Cai M, Tay LWR, Zhang F, Wu P, Huynh A, Cao X, Di Paolo G, Peng J, Milewicz DM, Du G. Phosphatidic acid generated by PLD2 promotes the plasma membrane recruitment of IQGAP1 and neointima formation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800390RR. PMID 30811216 DOI: 10.1096/Fj.201800390Rr  0.427
2018 Liang H, Estes MK, Zhang H, Du G, Zhou Y. Bile acids target proteolipid nano-assemblies of EGFR and phosphatidic acid in the plasma membrane for stimulation of MAPK signaling. Plos One. 13: e0198983. PMID 30169511 DOI: 10.1371/Journal.Pone.0198983  0.413
2017 Wang Z, Zhang F, He J, Wu P, Tay LWR, Cai M, Nian W, Weng Y, Qin L, Chang JT, McIntire LB, Di Paolo G, Xu J, Peng J, Du G. Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells. Developmental Cell. PMID 29033361 DOI: 10.1016/J.Devcel.2017.09.012  0.373
2017 Li Y, Wang W, Wang F, Wu Q, Li W, Zhong X, Tian K, Zeng T, Gao L, Liu Y, Li S, Jiang X, Du G, Zhou Y. Paired related homeobox 1 transactivates dopamine D2 receptor to maintain propagation and tumorigenicity of glioma-initiating cells. Journal of Molecular Cell Biology. PMID 28486630 DOI: 10.1093/Jmcb/Mjx017  0.344
2017 Law F, Seo JH, Wang Z, DeLeon JL, Bolis Y, Brown A, Zong WX, Du G, Rocheleau CE. The VPS-34 PI3 kinase negatively regulates RAB-5 during endosome maturation. Journal of Cell Science. PMID 28455411 DOI: 10.1242/Jcs.194746  0.33
2017 He J, Zhang F, Tay LW, Boroda S, Nian W, Levental KR, Levental I, Harris TE, Chang JT, Du G. Lipin-1 regulation of phospholipid synthesis maintains endoplasmic reticulum homeostasis and is critical for triple-negative breast cancer cell survival. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28347999 DOI: 10.1096/Fj.201601353R  0.378
2017 Tay LW, Wang Z, Du G. Analysis of Phosphatidic Acid Binding and Regulation of PIPKI In Vitro and in Intact Cells. Methods in Enzymology. 583: 359-374. PMID 28063499 DOI: 10.1016/Bs.Mie.2016.09.043  0.454
2016 Cai M, He J, Xiong J, Tay LW, Wang Z, Rog C, Wang J, Xie Y, Wang G, Banno Y, Li F, Zhu M, Du G. Phospholipase D1-regulated autophagy supplies free fatty acids to counter nutrient stress in cancer cells. Cell Death & Disease. 7: e2448. PMID 27809301 DOI: 10.1038/Cddis.2016.355  0.357
2016 Jaber N, Mohd-Naim N, Wang Z, DeLeon JL, Kim S, Zhong H, Sheshadri N, Dou Z, Edinger AL, Du G, Braga VM, Zong WX. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase activating protein Armus. Journal of Cell Science. PMID 27793976 DOI: 10.1242/Jcs.192260  0.423
2016 Jiang Y, Sverdlov MS, Toth PT, Huang L, Du G, Liu Y, Natarajan V, Minshall RD. Phosphatidic acid produced by RalA-activated PLD2 stimulates caveolae-mediated endocytosis and trafficking in endothelial cells. The Journal of Biological Chemistry. PMID 27510034 DOI: 10.1074/Jbc.M116.752485  0.461
2016 Lu M, Tay LW, He J, Du G. Monitoring Phosphatidic Acid Signaling in Breast Cancer Cells Using Genetically Encoded Biosensors. Methods in Molecular Biology (Clifton, N.J.). 1406: 225-37. PMID 26820960 DOI: 10.1007/978-1-4939-3444-7_20  0.354
2016 Wang Z, Liang X, Cai M, Du G. Analysis of Invadopodia Formation in Breast Cancer Cells. Methods in Molecular Biology (Clifton, N.J.). 1406: 203-10. PMID 26820958 DOI: 10.1007/978-1-4939-3444-7_18  0.311
2015 Li L, Chang J, Du G, Amato R, Li W. Abstract 1433: CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression Cancer Research. 75: 1433-1433. DOI: 10.1158/1538-7445.Am2015-1433  0.325
2015 Wang J, Xuan Y, Guo W, Du G, Deng W. Abstract 1019: hnRNPA2/B1 upregulates COX-2 expression and tumor growth and predicts poor prognosis in human lung cancers Cancer Research. 75: 1019-1019. DOI: 10.1158/1538-7445.Am2015-1019  0.319
2014 Li L, Liu C, Amato RJ, Chang JT, Du G, Li W. CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression. Oncotarget. 5: 10840-53. PMID 25333262 DOI: 10.18632/Oncotarget.2535  0.329
2014 Guo W, Lu J, Dai M, Wu T, Yu Z, Wang J, Chen W, Shi D, Yu W, Xiao Y, Yi C, Tang Z, Xu T, Xiao X, Yuan Y, ... ... Du G, et al. Transcriptional coactivator CBP upregulates hTERT expression and tumor growth and predicts poor prognosis in human lung cancers. Oncotarget. 5: 9349-61. PMID 25294805 DOI: 10.18632/Oncotarget.2430  0.333
2014 Feng X, Huang Y, Lu Y, Xiong J, Wong CO, Yang P, Xia J, Chen D, Du G, Venkatachalam K, Xia X, Zhu MX. Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane. The Journal of Biological Chemistry. 289: 4262-72. PMID 24375408 DOI: 10.1074/Jbc.M113.506501  0.345
2014 Zhang F, Wang Z, Lu M, Yonekubo Y, Liang X, Zhang Y, Wu P, Zhou Y, Grinstein S, Hancock JF, Du G. Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells. Molecular and Cellular Biology. 34: 84-95. PMID 24164897 DOI: 10.1128/Mcb.00987-13  0.425
2013 Schlam D, Bohdanowicz M, Chatgilialoglu A, Chatilialoglu A, Steinberg BE, Ueyama T, Du G, Grinstein S, Fairn GD. Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. The Journal of Biological Chemistry. 288: 23090-104. PMID 23814057 DOI: 10.1074/Jbc.M113.457606  0.354
2013 Bohdanowicz M, Schlam D, Hermansson M, Rizzuti D, Fairn GD, Ueyama T, Somerharju P, Du G, Grinstein S. Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Molecular Biology of the Cell. 24: 1700-12, S1-7. PMID 23576545 DOI: 10.1091/Mbc.E12-11-0789  0.446
2012 Roach AN, Wang Z, Wu P, Zhang F, Chan RB, Yonekubo Y, Di Paolo G, Gorfe AA, Du G. Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganization. Journal of Lipid Research. 53: 2598-609. PMID 22991193 DOI: 10.1194/Jlr.M028597  0.647
2012 Zhang F, Du G. Dysregulated lipid metabolism in cancer. World Journal of Biological Chemistry. 3: 167-74. PMID 22937213 DOI: 10.4331/Wjbc.V3.I8.167  0.33
2011 Yoon MS, Du G, Backer JM, Frohman MA, Chen J. Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway. The Journal of Cell Biology. 195: 435-47. PMID 22024166 DOI: 10.1083/Jcb.201107033  0.382
2011 Cho KJ, Hill MM, Chigurupati S, Du G, Parton RG, Hancock JF. Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2. Molecular and Cellular Biology. 31: 1110-20. PMID 21245384 DOI: 10.1128/Mcb.00989-10  0.357
2010 Tsukahara T, Tsukahara R, Fujiwara Y, Yue J, Cheng Y, Guo H, Bolen A, Zhang C, Balazs L, Re F, Du G, Frohman MA, Baker DL, Parrill AL, Uchiyama A, et al. Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid. Molecular Cell. 39: 421-32. PMID 20705243 DOI: 10.1016/J.Molcel.2010.07.022  0.392
2010 Ariotti N, Liang H, Xu Y, Zhang Y, Yonekubo Y, Inder K, Du G, Parton RG, Hancock JF, Plowman SJ. Epidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation. Molecular and Cellular Biology. 30: 3795-804. PMID 20516214 DOI: 10.1128/Mcb.01615-09  0.39
2010 Yin H, Gui Y, Du G, Frohman MA, Zheng XL. Dependence of phospholipase D1 multi-monoubiquitination on its enzymatic activity and palmitoylation. The Journal of Biological Chemistry. 285: 13580-8. PMID 20189990 DOI: 10.1074/Jbc.M109.046359  0.437
2010 Scotto-Lavino E, Garcia-Diaz M, Du G, Frohman MA. Basis for the isoform-specific interaction of myosin phosphatase subunits protein phosphatase 1c beta and myosin phosphatase targeting subunit 1. The Journal of Biological Chemistry. 285: 6419-24. PMID 20042605 DOI: 10.1074/Jbc.M109.074773  0.335
2009 Zhang Y, Du G. Phosphatidic acid signaling regulation of Ras superfamily of small guanosine triphosphatases. Biochimica Et Biophysica Acta. 1791: 850-5. PMID 19540930 DOI: 10.1016/J.Bbalip.2009.05.013  0.429
2009 Mor A, Wynne JP, Ahearn IM, Dustin ML, Du G, Philips MR. Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane. Molecular and Cellular Biology. 29: 3297-306. PMID 19332557 DOI: 10.1128/Mcb.00366-09  0.407
2009 Su W, Yeku O, Olepu S, Genna A, Park JS, Ren H, Du G, Gelb MH, Morris AJ, Frohman MA. 5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Molecular Pharmacology. 75: 437-46. PMID 19064628 DOI: 10.1124/Mol.108.053298  0.425
2009 Du G, Frohman MA. A lipid-signaled myosin phosphatase surge disperses cortical contractile force early in cell spreading. Molecular Biology of the Cell. 20: 200-8. PMID 18946083 DOI: 10.1091/Mbc.E08-06-0555  0.432
2009 Esechie A, Du G. Increased lipogenesis in cancer Communicative & Integrative Biology. 2: 545-548. DOI: 10.4161/Cib.2.6.9343  0.31
2008 Yang JS, Gad H, Lee SY, Mironov A, Zhang L, Beznoussenko GV, Valente C, Turacchio G, Bonsra AN, Du G, Baldanzi G, Graziani A, Bourgoin S, Frohman MA, Luini A, et al. A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenance. Nature Cell Biology. 10: 1146-53. PMID 18776900 DOI: 10.1038/Ncb1774  0.367
2007 Zeniou-Meyer M, Zabari N, Ashery U, Chasserot-Golaz S, Haeberlé AM, Demais V, Bailly Y, Gottfried I, Nakanishi H, Neiman AM, Du G, Frohman MA, Bader MF, Vitale N. Phospholipase D1 production of phosphatidic acid at the plasma membrane promotes exocytosis of large dense-core granules at a late stage. The Journal of Biological Chemistry. 282: 21746-57. PMID 17540765 DOI: 10.1074/Jbc.M702968200  0.425
2007 Mor A, Campi G, Du G, Zheng Y, Foster DA, Dustin ML, Philips MR. The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2. Nature Cell Biology. 9: 713-9. PMID 17486117 DOI: 10.1038/Ncb1592  0.362
2007 Zhao C, Du G, Skowronek K, Frohman MA, Bar-Sagi D. Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. Nature Cell Biology. 9: 706-12. PMID 17486115 DOI: 10.1038/Ncb1594  0.387
2006 LaLonde M, Janssens H, Yun S, Crosby J, Redina O, Olive V, Altshuller YM, Choi SY, Du G, Gergen JP, Frohman MA. A role for Phospholipase D in Drosophila embryonic cellularization. Bmc Developmental Biology. 6: 60. PMID 17156430 DOI: 10.1186/1471-213X-6-60  0.402
2006 Corrotte M, Chasserot-Golaz S, Huang P, Du G, Ktistakis NT, Frohman MA, Vitale N, Bader MF, Grant NJ. Dynamics and function of phospholipase D and phosphatidic acid during phagocytosis. Traffic (Copenhagen, Denmark). 7: 365-77. PMID 16497229 DOI: 10.1111/J.1600-0854.2006.00389.X  0.436
2006 Su W, Chardin P, Yamazaki M, Kanaho Y, Du G. RhoA-mediated Phospholipase D1 signaling is not required for the formation of stress fibers and focal adhesions. Cellular Signalling. 18: 469-78. PMID 15993039 DOI: 10.1016/J.Cellsig.2005.05.027  0.388
2005 Xiao N, Du G, Frohman MA. Peroxiredoxin II functions as a signal terminator for H2O2-activated phospholipase D1. The Febs Journal. 272: 3929-37. PMID 16045763 DOI: 10.1111/J.1742-4658.2005.04809.X  0.388
2005 Zhou Y, Du G, Hu X, Yu S, Liu Y, Xu Y, Huang X, Liu J, Yin B, Fan M, Peng X, Qiang B, Yuan J. Nectin-like molecule 1 is a protein 4.1N associated protein and recruits protein 4.1N from cytoplasm to the plasma membrane. Biochimica Et Biophysica Acta. 1669: 142-54. PMID 15893517 DOI: 10.1016/J.Bbamem.2005.01.013  0.369
2004 Zhang Y, Huang P, Du G, Kanaho Y, Frohman MA, Tsirka SE. Increased expression of two phospholipase D isoforms during experimentally induced hippocampal mossy fiber outgrowth. Glia. 46: 74-83. PMID 14999815 DOI: 10.1002/Glia.10322  0.325
2004 Du G, Huang P, Liang BT, Frohman MA. Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis. Molecular Biology of the Cell. 15: 1024-30. PMID 14718562 DOI: 10.1091/Mbc.E03-09-0673  0.395
2004 Zheng XL, Gui Y, Du G, Frohman MA, Peng DQ. Calphostin-C induction of vascular smooth muscle cell apoptosis proceeds through phospholipase D and microtubule inhibition. The Journal of Biological Chemistry. 279: 7112-8. PMID 14660552 DOI: 10.1074/Jbc.M310721200  0.304
2003 Fang Y, Park IH, Wu AL, Du G, Huang P, Frohman MA, Walker SJ, Brown HA, Chen J. PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1. Current Biology : Cb. 13: 2037-44. PMID 14653992 DOI: 10.1016/J.Cub.2003.11.021  0.41
2003 Ballou LM, Jiang YP, Du G, Frohman MA, Lin RZ. Ca(2+)- and phospholipase D-dependent and -independent pathways activate mTOR signaling. Febs Letters. 550: 51-6. PMID 12935885 DOI: 10.1016/S0014-5793(03)00816-0  0.368
2003 Du G, Altshuller YM, Vitale N, Huang P, Chasserot-Golaz S, Morris AJ, Bader MF, Frohman MA. Regulation of phospholipase D1 subcellular cycling through coordination of multiple membrane association motifs. The Journal of Cell Biology. 162: 305-15. PMID 12876278 DOI: 10.1083/Jcb.200302033  0.394
2002 Du G, Morris AJ, Sciorra VA, Frohman MA. G-protein-coupled receptor regulation of phospholipase D. Methods in Enzymology. 345: 265-74. PMID 11665610 DOI: 10.1016/S0076-6879(02)45022-7  0.419
2001 Humeau Y, Vitale N, Chasserot-Golaz S, Dupont JL, Du G, Frohman MA, Bader MF, Poulain B. A role for phospholipase D1 in neurotransmitter release. Proceedings of the National Academy of Sciences of the United States of America. 98: 15300-5. PMID 11752468 DOI: 10.1073/Pnas.261358698  0.356
2001 Wang J, Zhou Y, Yin B, Du G, Huang X, Li G, Shen Y, Yuan J, Qiang B. ASH2L: Alternative splicing and downregulation during induced megakaryocytic differentiation of multipotential leukemia cell lines Journal of Molecular Medicine. 79: 399-405. PMID 11466562 DOI: 10.1007/S001090100222  0.328
2001 Vitale N, Caumont AS, Chasserot-Golaz S, Du G, Wu S, Sciorra VA, Morris AJ, Frohman MA, Bader MF. Phospholipase D1: a key factor for the exocytotic machinery in neuroendocrine cells. The Embo Journal. 20: 2424-34. PMID 11350931 DOI: 10.1093/Emboj/20.10.2424  0.434
2000 Du G, Altshuller YM, Kim Y, Han JM, Ryu SH, Morris AJ, Frohman MA. Dual requirement for rho and protein kinase C in direct activation of phospholipase D1 through G protein-coupled receptor signaling. Molecular Biology of the Cell. 11: 4359-68. PMID 11102529 DOI: 10.1091/Mbc.11.12.4359  0.39
2000 Park JB, Kim JH, Kim Y, Ha SH, Yoo JS, Du G, Frohman MA, Suh PG, Ryu SH. Cardiac phospholipase D2 localizes to sarcolemmal membranes and is inhibited by alpha-actinin in an ADP-ribosylation factor-reversible manner. The Journal of Biological Chemistry. 275: 21295-301. PMID 10801846 DOI: 10.1074/Jbc.M002463200  0.348
2000 Slaaby R, Du G, Altshuller YM, Frohman MA, Seedorf K. Insulin-induced phospholipase D1 and phospholipase D2 activity in human embryonic kidney-293 cells mediated by the phospholipase Cγ and protein kinase Cα signalling cascade Biochemical Journal. 351: 613-619. DOI: 10.1042/0264-6021:3510613  0.366
1999 Zhou Y, Du G, Wang J, Chen J, Yuan J, Qiang B. Isolation and cloning of a novel cDNALDB1 encoding human LIM domain binding protein Chinese Science Bulletin. 44: 1114-1119. DOI: 10.1007/Bf02886138  0.302
1999 Wang J, Du G, Zhou Y, Yin B, Yuan J, Qiang B. Cloning and identification of PHF2 cDNA and its alternatively spliced transcripts Chinese Science Bulletin. 44: 1382-1387. DOI: 10.1007/Bf02885987  0.318
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