| Year |
Citation |
Score |
| 2023 |
López-Tena M, Farrera-Soler L, Barluenga S, Winssinger N. Pseudo-Complementary G:C Base Pair for Mixed Sequence dsDNA Invasion and Its Applications in Diagnostics (SARS-CoV-2 Detection). Jacs Au. 3: 449-458. PMID 36873687 DOI: 10.1021/jacsau.2c00588 |
0.628 |
|
| 2022 |
Patouret R, Barluenga S, Winssinger N. Withaferin A, a polyfunctional pharmacophore that includes covalent engagement of IPO5, is an inhibitor of influenza A replication. Bioorganic & Medicinal Chemistry. 69: 116883. PMID 35772286 DOI: 10.1016/j.bmc.2022.116883 |
0.633 |
|
| 2022 |
Farrera-Soler L, Gonse A, Kim KT, Barluenga S, Winssinger N. Combining recombinase polymerase amplification and DNA-templated reaction for SARS-CoV-2 sensing with dual fluorescence and lateral flow assay output. Biopolymers. e23485. PMID 35023571 DOI: 10.1002/bip.23485 |
0.635 |
|
| 2021 |
Vummidi BR, Farrera-Soler L, Daguer JP, Dockerill M, Barluenga S, Winssinger N. A mating mechanism to generate diversity for the Darwinian selection of DNA-encoded synthetic molecules. Nature Chemistry. PMID 34873299 DOI: 10.1038/s41557-021-00829-5 |
0.671 |
|
| 2021 |
Sabale PM, Imiołek M, Raia P, Barluenga S, Winssinger N. Suprastapled Peptides: Hybridization-Enhanced Peptide Ligation and Enforced α-Helical Conformation for Affinity Selection of Combinatorial Libraries. Journal of the American Chemical Society. 143: 18932-18940. PMID 34739233 DOI: 10.1021/jacs.1c07013 |
0.637 |
|
| 2021 |
Pagano S, Yerly S, Meyer B, Juillard C, Suh N, Le Terrier C, Daguer JP, Farrera-Soler L, Barluenga S, Piumatti G, Hartley O, Lemaitre B, Eberhardt CS, Siegrist CA, Eckerle I, et al. SARS-CoV2- infection as a trigger of humoral response against apolipoprotein A-1. European Journal of Clinical Investigation. e13661. PMID 34324704 DOI: 10.1111/eci.13661 |
0.606 |
|
| 2021 |
Liu W, Patouret R, Barluenga S, Plank M, Loewith R, Winssinger N. Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides. Acs Central Science. 7: 954-962. PMID 34235256 DOI: 10.1021/acscentsci.1c00056 |
0.693 |
|
| 2021 |
Daguer JP, Gonse A, Shchukin Y, Farrera-Soler L, Barluenga S, Winssinger N. Dual Bcl-X /Bcl-2 inhibitors discovered from DNA-encoded libraries using a fragment pairing strategy. Bioorganic & Medicinal Chemistry. 44: 116282. PMID 34216984 DOI: 10.1016/j.bmc.2021.116282 |
0.674 |
|
| 2021 |
Farrera-Soler L, Daguer JP, Barluenga S, Winssinger N. Experimental Identification of Immuno- dominant B-cell Epitopes from SARS-CoV-2. Chimia. 75: 276-284. PMID 33902795 DOI: 10.2533/chimia.2021.276 |
0.605 |
|
| 2020 |
Farrera-Soler L, Daguer JP, Barluenga S, Vadas O, Cohen P, Pagano S, Yerly S, Kaiser L, Vuilleumier N, Winssinger N. Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma. Plos One. 15: e0238089. PMID 32903266 DOI: 10.1371/Journal.Pone.0238089 |
0.635 |
|
| 2020 |
Streuff J, Echavarren AM, González JM, Oestreich M, Gansäuer A, Barluenga S, Winssinger N. Kilian Muñiz (1970-2020). Angewandte Chemie (International Ed. in English). PMID 32249993 DOI: 10.1002/Anie.202004481 |
0.631 |
|
| 2020 |
Farrera-Soler L, Daguer JP, Raunft P, Barluenga S, Imberty A, Winssinger N. PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectins. Bioorganic & Medicinal Chemistry. 115458. PMID 32241620 DOI: 10.1016/J.Bmc.2020.115458 |
0.692 |
|
| 2020 |
Saarbach J, Barluenga S, Winssinger N. PNA-Encoded Synthesis (PES) and DNA Display of Small Molecule Libraries. Methods in Molecular Biology (Clifton, N.J.). 2105: 119-139. PMID 32088867 DOI: 10.1007/978-1-0716-0243-0_7 |
0.708 |
|
| 2019 |
Figuerola-Conchas A, Saarbach J, Daguer JP, Cieren A, Barluenga S, Winssinger N, Gotta M. Small-molecule modulators of the ATPase VCP/p97 affect specific p97 cellular functions. Acs Chemical Biology. PMID 31790201 DOI: 10.1021/Acschembio.9B00832 |
0.65 |
|
| 2019 |
Laurent Q, Berthet M, Cheng Y, Sakai N, Barluenga S, Winssinger N, Matile S. Probing for Thiol-Mediated Uptake into Bacteria. Chembiochem : a European Journal of Chemical Biology. PMID 31603284 DOI: 10.1002/Cbic.201900378 |
0.632 |
|
| 2016 |
Versele M, Haefner B, Wroblowski B, Stansfield I, Mevellec L, Gilissen R, Neumann L, Augustin M, Jacobs K, Cools J, Barluenga S, Röthlingshöfer M, Karthikeyan G, Attar R, Meerpoel L, et al. Abstract 4800: Covalent Flt3-Cys828 inhibition represents a novel therapeutic approach for the treatment of Flt3-ITD and Flt3-D835 mutant acute myeloid leukemia Cancer Research. 76: 4800-4800. DOI: 10.1158/1538-7445.Am2016-4800 |
0.675 |
|
| 2016 |
Zambaldo C, Daguer J, Saarbach J, Barluenga S, Winssinger N. Screening for covalent inhibitors using DNA-display of small molecule libraries functionalized with cysteine reactive moieties Medchemcomm. 7: 1340-1351. DOI: 10.1039/C6Md00242K |
0.689 |
|
| 2015 |
Daguer JP, Zambaldo C, Ciobanu M, Morieux P, Barluenga S, Winssinger N. DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules. Chemical Science. 6: 739-744. PMID 30154995 DOI: 10.1039/C4Sc01654H |
0.704 |
|
| 2015 |
Barluenga S, Zambaldo C, Ioannidou HA, Ciobanu M, Morieux P, Daguer JP, Winssinger N. Novel PTP1B inhibitors identified by DNA display of fragment pairs. Bioorganic & Medicinal Chemistry Letters. PMID 26691757 DOI: 10.1016/J.Bmcl.2015.11.102 |
0.696 |
|
| 2015 |
Viéville JM, Barluenga S, Winssinger N, Delsuc MA. Duplex formation and secondary structure of γ-PNA observed by NMR and CD. Biophysical Chemistry. PMID 26493008 DOI: 10.1016/J.Bpc.2015.09.002 |
0.659 |
|
| 2015 |
Barluenga S, Winssinger N. PNA as a Biosupramolecular Tag for Programmable Assemblies and Reactions. Accounts of Chemical Research. 48: 1319-31. PMID 25947113 DOI: 10.1021/Acs.Accounts.5B00109 |
0.704 |
|
| 2015 |
Daguer JP, Zambaldo C, Abegg D, Barluenga S, Tallant C, Müller S, Adibekian A, Winssinger N. Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules. Angewandte Chemie (International Ed. in English). 54: 6057-61. PMID 25772490 DOI: 10.1002/Anie.201412276 |
0.669 |
|
| 2015 |
Zambaldo C, Barluenga S, Winssinger N. PNA-encoded chemical libraries. Current Opinion in Chemical Biology. 26: 8-15. PMID 25621730 DOI: 10.1016/J.Cbpa.2015.01.005 |
0.715 |
|
| 2015 |
Daguer JP, Zambaldo C, Ciobanu M, Morieux P, Barluenga S, Winssinger N. DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules Chemical Science. 6: 739-744. DOI: 10.1039/c4sc01654h |
0.647 |
|
| 2015 |
Daguer J, Zambaldo C, Abegg D, Barluenga S, Tallant C, Müller S, Adibekian A, Winssinger N. Identifizierung von niedermolekularen kovalenten Bromodomäne-Bindern aus einer DNA-kodierten Bibliothek Angewandte Chemie. 127: 6155-6159. DOI: 10.1002/Ange.201412276 |
0.622 |
|
| 2014 |
Novoa A, Machida T, Barluenga S, Imberty A, Winssinger N. PNA-encoded synthesis (PES) of a 10 000-member hetero-glycoconjugate library and microarray analysis of diverse lectins. Chembiochem : a European Journal of Chemical Biology. 15: 2058-65. PMID 25158314 DOI: 10.1002/Cbic.201402280 |
0.689 |
|
| 2014 |
Novoa A, Eierhoff T, Topin J, Varrot A, Barluenga S, Imberty A, Römer W, Winssinger N. A LecA ligand identified from a galactoside-conjugate array inhibits host cell invasion by Pseudomonas aeruginosa. Angewandte Chemie (International Ed. in English). 53: 8885-9. PMID 25044671 DOI: 10.1002/Anie.201402831 |
0.646 |
|
| 2014 |
Winssinger N, Gorska K, Ciobanu M, Daguer JP, Barluenga S. Assembly of PNA-tagged small molecules, peptides, and carbohydrates onto DNA templates: programming the combinatorial pairing and inter-ligand distance. Methods in Molecular Biology (Clifton, N.J.). 1050: 95-110. PMID 24297353 DOI: 10.1007/978-1-62703-553-8_8 |
0.685 |
|
| 2014 |
Duplan V, Serba C, Garcia J, Valot G, Barluenga S, Hoerlé M, Cuendet M, Winssinger N. Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway. Organic & Biomolecular Chemistry. 12: 370-5. PMID 24263232 DOI: 10.1039/C3Ob42049C |
0.711 |
|
| 2013 |
Barluenga S, Winssinger N. Picture perfect: DNA-templated photoaffinity labeling. Chembiochem : a European Journal of Chemical Biology. 14: 1927-8. PMID 24006240 DOI: 10.1002/Cbic.201300416 |
0.675 |
|
| 2013 |
Novoa A, Barluenga S, Serba C, Winssinger N. Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates. Chemical Communications (Cambridge, England). 49: 7608-10. PMID 23882465 DOI: 10.1039/C3Cc43458C |
0.671 |
|
| 2013 |
Kazane SA, Axup JY, Kim CH, Ciobanu M, Wold ED, Barluenga S, Hutchins BA, Schultz PG, Winssinger N, Smider VV. Self-assembled antibody multimers through peptide nucleic acid conjugation. Journal of the American Chemical Society. 135: 340-6. PMID 23210862 DOI: 10.1021/Ja309505C |
0.667 |
|
| 2013 |
Zambaldo C, Sadhu KK, Karthikeyan G, Barluenga S, Daguer JP, Winssinger N. Selective affinity-based probe for oncogenic kinases suitable for live cell imaging Chemical Science. 4: 2088-2092. DOI: 10.1039/C3Sc21856B |
0.669 |
|
| 2012 |
Chouikhi D, Ciobanu M, Zambaldo C, Duplan V, Barluenga S, Winssinger N. Expanding the scope of PNA-encoded synthesis (PES): Mtt-protected PNA fully orthogonal to fmoc chemistry and a broad array of robust diversity-generating reactions. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 12698-704. PMID 22915361 DOI: 10.1002/Chem.201201337 |
0.722 |
|
| 2012 |
Karthikeyan G, Zambaldo C, Barluenga S, Zoete V, Karplus M, Winssinger N. Asymmetric synthesis of pochonin E and F, revision of their proposed structure, and their conversion to potent Hsp90 inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 8978-86. PMID 22696415 DOI: 10.1002/Chem.201200546 |
0.669 |
|
| 2012 |
Valot G, Garcia J, Duplan V, Serba C, Barluenga S, Winssinger N. Diversity-oriented synthesis of diverse polycyclic scaffolds inspired by the logic of sesquiterpene lactones biosynthesis. Angewandte Chemie (International Ed. in English). 51: 5391-4. PMID 22517777 DOI: 10.1002/Anie.201201157 |
0.685 |
|
| 2012 |
Daguer JP, Ciobanu M, Barluenga S, Winssinger N. Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries. Organic & Biomolecular Chemistry. 10: 1502-5. PMID 22237952 DOI: 10.1039/C2Ob06880J |
0.675 |
|
| 2012 |
Hamidi A, von Bulow V, Hamidi R, Winssinger N, Barluenga S, Heldin CH, Landström M. Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli. The Journal of Biological Chemistry. 287: 123-33. PMID 22069318 DOI: 10.1074/Jbc.M111.285122 |
0.617 |
|
| 2012 |
Garcia J, Barluenga S, Gorska K, Sasse F, Winssinger N. Synthesis of deguelin-biotin conjugates and investigation into deguelin's interactions. Bioorganic & Medicinal Chemistry. 20: 672-80. PMID 22037048 DOI: 10.1016/J.Bmc.2011.09.064 |
0.678 |
|
| 2011 |
Ciobanu M, Huang KT, Daguer JP, Barluenga S, Chaloin O, Schaeffer E, Mueller CG, Mitchell DA, Winssinger N. Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells. Chemical Communications (Cambridge, England). 47: 9321-3. PMID 21785785 DOI: 10.1039/C1Cc13213J |
0.686 |
|
| 2011 |
Gorska K, Manicardi A, Barluenga S, Winssinger N. DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker. Chemical Communications (Cambridge, England). 47: 4364-6. PMID 21369617 DOI: 10.1039/C1Cc10222B |
0.68 |
|
| 2011 |
Leproult E, Barluenga S, Moras D, Wurtz JM, Winssinger N. Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors. Journal of Medicinal Chemistry. 54: 1347-55. PMID 21322567 DOI: 10.1021/Jm101396Q |
0.68 |
|
| 2011 |
Huang KT, Gorska K, Alvarez S, Barluenga S, Winssinger N. Combinatorial self-assembly of glycan fragments into microarrays. Chembiochem : a European Journal of Chemical Biology. 12: 56-60. PMID 21154493 DOI: 10.1002/Cbic.201000567 |
0.677 |
|
| 2011 |
Daguer JP, Ciobanu M, Alvarez S, Barluenga S, Winssinger N. DNA-templated combinatorial assembly of small molecule fragments amenable to selection/amplification cycles Chemical Science. 2: 625-632. DOI: 10.1039/C0Sc00574F |
0.703 |
|
| 2010 |
Grad I, Cederroth CR, Walicki J, Grey C, Barluenga S, Winssinger N, De Massy B, Nef S, Picard D. The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse. Plos One. 5: e15770. PMID 21209834 DOI: 10.1371/Journal.Pone.0015770 |
0.65 |
|
| 2010 |
Zhu H, Woolfenden S, Bronson RT, Jaffer ZM, Barluenga S, Winssinger N, Rubenstein AE, Chen R, Charest A. The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme. Molecular Cancer Therapeutics. 9: 2618-26. PMID 20643786 DOI: 10.1158/1535-7163.Mct-10-0248 |
0.667 |
|
| 2010 |
Barluenga S, Jogireddy R, Koripelly GK, Winssinger N. In vivo efficacy of natural product-inspired irreversible kinase inhibitors. Chembiochem : a European Journal of Chemical Biology. 11: 1692-9. PMID 20623569 DOI: 10.1002/Cbic.201000205 |
0.688 |
|
| 2010 |
Garcia J, Barluenga S, Beebe K, Neckers L, Winssinger N. Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 9767-71. PMID 20572190 DOI: 10.1002/Chem.201001080 |
0.676 |
|
| 2010 |
Chouikhi D, Barluenga S, Winssinger N. Clickable peptide nucleic acids (cPNA) with tunable affinity. Chemical Communications (Cambridge, England). 46: 5476-8. PMID 20571635 DOI: 10.1039/C0Cc01081B |
0.692 |
|
| 2010 |
Jogireddy R, Barluenga S, Winssinger N. Molecular editing of kinase-targeting resorcylic acid lactones (RAL): Fluoroenone RAL. Chemmedchem. 5: 670-3. PMID 20209566 DOI: 10.1002/Cmdc.201000047 |
0.694 |
|
| 2010 |
Jogireddy R, Barluenga S, Winssinger N. Cover Picture: Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL (ChemMedChem 5/2010) Chemmedchem. 5: 633-633. DOI: 10.1002/Cmdc.201090015 |
0.666 |
|
| 2010 |
Nicolaou KC, Baran PS, Zhong Y, Barluenga S, Hunt KW, Kranich R, Vega JA. ChemInform Abstract: Iodine(V) Reagents in Organic Synthesis. Part 3. New Routes to Heterocyclic Compounds via o-Iodoxybenzoic Acid-Mediated Cyclizations: Generality, Scope, and Mechanism. Cheminform. 33: no-no. DOI: 10.1002/chin.200231035 |
0.545 |
|
| 2010 |
Nicolaou KC, Murphy F, Barluenga S, Ohshima T, Wei H, Xu J, Gray DLF, Baudoin O. ChemInform Abstract: Total Synthesis of the Novel Immunosuppressant Sanglifehrin A (I). Cheminform. 31: no-no. DOI: 10.1002/chin.200030237 |
0.641 |
|
| 2010 |
Barluenga J, Aznar F, Palomero MA, Barluenga S. ChemInform Abstract: Unexpected Thermal Benzannulation of 1,3,5-Metallahexatrienes: Synthesis of o-Alkoxyphenol-Containing Polycycles. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199949044 |
0.342 |
|
| 2010 |
Nicolaou KC, Xu J, Murphy F, Barluenga S, Baudoin O, Wei H, Gray DLF, Ohshima T. ChemInform Abstract: Total Synthesis of Sanglifehrin A. Cheminform. 30: no-no. DOI: 10.1002/chin.199947252 |
0.63 |
|
| 2010 |
Nicolaou KC, Ohshima T, Murphy F, Barluenga S, Xu J, Winssinger N. ChemInform Abstract: Synthesis of the Macrocyclic Core of Sanglifehrin A. Cheminform. 30: no-no. DOI: 10.1002/chin.199934254 |
0.689 |
|
| 2010 |
Barluenga J, Aznar F, Barluenga S, Fernandez M, Martin A, Garcia-Granda S, Pinera-Nicolas A. ChemInform Abstract: Reactions of 2-Amino-1,3-butadienes and Fischer Alkynyl Carbenes: Up to Nine C-C Bonds and Seven Stereogenic Centers Created in a Stereoselective Manner Through a Cascade Process. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199912073 |
0.347 |
|
| 2010 |
NICOLAOU KC, PASTOR J, BARLUENGA S, WINSSINGER N. ChemInform Abstract: Polymer-Supported Selenium Reagents for Organic Synthesis. Cheminform. 30: no-no. DOI: 10.1002/chin.199902057 |
0.662 |
|
| 2010 |
BARLUENGA J, AZNAR F, BARLUENGA S, MARTIN A, GARCIA-GRANDA S, MARTIN E. ChemInform Abstract: Tandem Cycloaddition-Cyclopentannulation Processes of 2-Aminobuta-1,3-dienes and Fischer Alkynylcarbene Complexes as a Tool for the Preparation of Complex Polycyclic Scaffolds. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199834124 |
0.332 |
|
| 2010 |
BARLUENGA J, AZNAR F, BARLUENGA S, GARCIA-GRANDA S, ALVAREZ-RUA C. ChemInform Abstract: Stereospecific [4 + 2] Reaction Between 2-Morpholino-1,3-butadienes and α,β-Unsaturated Exocyclic Chromium Carbene Complexes. Preparation of Enantiomerically Pure Spiro Compounds. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199803066 |
0.348 |
|
| 2010 |
BARLUENGA J, AZNAR F, MARTIN A, BARLUENGA S. ChemInform Abstract: Enantioselective Synthesis of Six Membered Carbocycles Through (4 + 2) Cycloaddition Reactions of Chiral 2-Amino-1,3-butadienes and Tungsten Vinyl Fischer Type Carbene Complexes. Cheminform. 28: no-no. DOI: 10.1002/CHIN.199748220 |
0.41 |
|
| 2010 |
BARLUENGA J, AZNAR F, BARLUENGA S. ChemInform Abstract: Unexpected and Easy Annulation of Fischer-Type Phenylethenyl Carbene Complexes. Cheminform. 27: no-no. DOI: 10.1002/CHIN.199608103 |
0.31 |
|
| 2010 |
BARLUENGA J, AZNAR F, MARTIN A, BARLUENGA S, GARCIA-GRANDA S, PANEQUE-QUEVEDO AA. ChemInform Abstract: First (4 + 2) Cycloaddition Reaction Between Vinyl Fischer Type Carbene Complexes and Chiral 2-Amino-1,3-dienes. Cheminform. 25: no-no. DOI: 10.1002/CHIN.199435061 |
0.372 |
|
| 2010 |
Barluenga S, Dakas PY, Jogireddy R, Valot G, Winssinger N. Metathesis Reactions in Solid-Phase Organic Synthesis Metathesis in Natural Product Synthesis: Strategies, Substrates and Catalysts. 349-372. DOI: 10.1002/9783527629626.ch13 |
0.633 |
|
| 2009 |
Winssinger N, Fontaine JG, Barluenga S. Hsp90 inhibition with resorcyclic acid lactones (RALs). Current Topics in Medicinal Chemistry. 9: 1419-35. PMID 19860733 DOI: 10.2174/156802609789895665 |
0.682 |
|
| 2009 |
Barluenga S, Fontaine JG, Wang C, Aouadi K, Chen R, Beebe K, Neckers L, Winssinger N. Inhibition of HSP90 with pochoximes: SAR and structure-based insights. Chembiochem : a European Journal of Chemical Biology. 10: 2753-9. PMID 19856365 DOI: 10.1002/Cbic.200900494 |
0.683 |
|
| 2009 |
Jogireddy R, Dakas PY, Valot G, Barluenga S, Winssinger N. Synthesis of a resorcylic acid lactone (RAL) library using fluorous-mixture synthesis and profile of its selectivity against a panel of kinases. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 11498-506. PMID 19821461 DOI: 10.1002/Chem.200901375 |
0.708 |
|
| 2009 |
Dakas PY, Jogireddy R, Valot G, Barluenga S, Winssinger N. Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 11490-7. PMID 19821460 DOI: 10.1002/Chem.200901373 |
0.684 |
|
| 2009 |
Spichty M, Taly A, Hagn F, Kessler H, Barluenga S, Winssinger N, Karplus M. The HSP90 binding mode of a radicicol-like E-oxime determined by docking, binding free energy estimations, and NMR 15N chemical shifts. Biophysical Chemistry. 143: 111-23. PMID 19482409 DOI: 10.1016/J.Bpc.2009.04.003 |
0.656 |
|
| 2009 |
Wang C, Barluenga S, Koripelly GK, Fontaine JG, Chen R, Yu JC, Shen X, Chabala JC, Heck JV, Rubenstein A, Winssinger N. Synthesis of pochoxime prodrugs as potent HSP90 inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 3836-40. PMID 19410458 DOI: 10.1016/J.Bmcl.2009.04.030 |
0.684 |
|
| 2009 |
Dakas P, Jogireddy R, Valot G, Barluenga S, Winssinger N. Cover Picture: Divergent Syntheses of Resorcylic Acid Lactones: L-783277, LL-Z1640-2, and Hypothemycin / Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases (Chem. Chemistry - a European Journal. 15: 11409-11409. DOI: 10.1002/Chem.200990168 |
0.699 |
|
| 2009 |
Winssinger N, Barluenga S, Dakas PY. High-Throughput Synthesis of Natural Products The Power of Functional Resins in Organic Synthesis. 613-640. DOI: 10.1002/9783527626175.ch21 |
0.646 |
|
| 2008 |
García-Cuadrado D, Barluenga S, Winssinger N. Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents. Chemical Communications (Cambridge, England). 4619-21. PMID 18815703 DOI: 10.1039/B807869F |
0.688 |
|
| 2008 |
Barluenga S, Wang C, Fontaine JG, Aouadi K, Beebe K, Tsutsumi S, Neckers L, Winssinger N. Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor. Angewandte Chemie (International Ed. in English). 47: 4432-5. PMID 18435518 DOI: 10.1002/Anie.200800233 |
0.699 |
|
| 2008 |
Barluenga S, Dakas PY, Boulifa M, Moulin E, Winssinger N. Resorcylic acid lactones: A pluripotent scaffold with therapeutic potential Comptes Rendus Chimie. 11: 1306-1317. DOI: 10.1016/J.Crci.2008.01.020 |
0.662 |
|
| 2007 |
Dakas PY, Barluenga S, Totzke F, Zirrgiebel U, Winssinger N. Modular synthesis of radicicol A and related resorcylic acid lactones, potent kinase inhibitors. Angewandte Chemie (International Ed. in English). 46: 6899-902. PMID 17676571 DOI: 10.1002/Anie.200702406 |
0.67 |
|
| 2007 |
Winssinger N, Barluenga S. Chemistry and biology of resorcylic acid lactones. Chemical Communications (Cambridge, England). 22-36. PMID 17279252 DOI: 10.1039/B610344H |
0.697 |
|
| 2007 |
Winssinger N, Pianowski Z, Barluenga S. Chemical Technologies: Probing Biology with Small Molecules Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine. 109-144. DOI: 10.1002/9780470199138.ch5 |
0.615 |
|
| 2006 |
Moulin E, Barluenga S, Totzke F, Winssinger N. Diversity-oriented synthesis of pochonins and biological evaluation against a panel of kinases. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 8819-34. PMID 16953513 DOI: 10.1002/Chem.200600553 |
0.706 |
|
| 2006 |
Barluenga S, Dakas PY, Ferandin Y, Meijer L, Winssinger N. Modular asymmetric synthesis of aigialomycin D, a kinase-inhibitory scaffold. Angewandte Chemie (International Ed. in English). 45: 3951-4. PMID 16683294 DOI: 10.1002/Anie.200600593 |
0.694 |
|
| 2006 |
Winssinger N, Barluenga S, Dakas P, Ferandin Y, Meijer L. Polymer-Supported Synthesis of Aigialomycin D Synfacts. 2006: 0961-0961. DOI: 10.1055/S-2006-949249 |
0.613 |
|
| 2006 |
Barluenga S, Moulin E, Lopez P, Winssinger N. Solution- and Solid-Phase Synthesis of Radicicol (Monorden) (I) and Pochonin C (II). Cheminform. 37. DOI: 10.1002/chin.200615210 |
0.609 |
|
| 2005 |
Moulin E, Barluenga S, Winssinger N. Concise synthesis of pochonin A, an HSP90 inhibitor. Organic Letters. 7: 5637-9. PMID 16321010 DOI: 10.1021/Ol052263+ |
0.707 |
|
| 2005 |
Barluenga S, Moulin E, Lopez P, Winssinger N. Solution- and solid-phase synthesis of radicicol (monorden) and pochonin C. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 4935-52. PMID 15940738 DOI: 10.1002/Chem.200500160 |
0.686 |
|
| 2005 |
Moulin E, Zoete V, Barluenga S, Karplus M, Winssinger N. Design, synthesis, and biological evaluation of HSP90 inhibitors based on conformational analysis of radicicol and its analogues. Journal of the American Chemical Society. 127: 6999-7004. PMID 15884943 DOI: 10.1021/Ja043101W |
0.694 |
|
| 2004 |
Barluenga S, Lopez P, Moulin E, Winssinger N. Modular asymmetric synthesis of pochonin C. Angewandte Chemie (International Ed. in English). 43: 3467-70. PMID 15221842 DOI: 10.1002/Anie.200454108 |
0.661 |
|
| 2004 |
Barluenga S, Simonsen KB, Littlefield ES, Ayida BK, Vourloumis D, Winters GC, Takahashi M, Shandrick S, Zhao Q, Han Q, Hermann T. Rational design of azepane-glycoside antibiotics targeting the bacterial ribosome. Bioorganic & Medicinal Chemistry Letters. 14: 713-8. PMID 14741274 DOI: 10.1016/J.Bmcl.2003.11.028 |
0.301 |
|
| 2003 |
Vourloumis D, Takahashi M, Simonsen KB, Ayida BK, Barluenga S, Winters GC, Hermann T. Solid-phase synthesis of benzimidazole libraries biased for RNA targets Tetrahedron Letters. 44: 2807-2811. DOI: 10.1016/S0040-4039(03)00453-2 |
0.323 |
|
| 2002 |
Nicholas GM, Eckman LL, Ray S, Hughes RO, Pfefferkorn JA, Barluenga S, Nicolaou KC, Bewley CA. Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase. Bioorganic & Medicinal Chemistry Letters. 12: 2487-90. PMID 12161164 DOI: 10.1016/S0960-894X(02)00385-2 |
0.737 |
|
| 2002 |
Nicolaou KC, Baran PS, Zhong YL, Barluenga S, Hunt KW, Kranich R, Vega JA. Iodine(V) reagents in organic synthesis. Part 3. New routes to heterocyclic compounds via o-iodoxybenzoic acid-mediated cyclizations: generality, scope, and mechanism. Journal of the American Chemical Society. 124: 2233-44. PMID 11878977 DOI: 10.1021/ja012126h |
0.565 |
|
| 2001 |
Nicolaou KC, Roecker AJ, Barluenga S, Pfefferkorn JA, Cao GQ. Discovery of novel antibacterial agents active against methicillin-resistant Staphylococcus aureus from combinatorial benzopyran libraries. Chembiochem : a European Journal of Chemical Biology. 2: 460-5. PMID 11828478 DOI: 10.1002/1439-7633(20010601)2:6<460::Aid-Cbic460>3.0.Co;2-2 |
0.756 |
|
| 2001 |
Nicolaou KC, Hughes R, Pfefferkorn JA, Barluenga S. Optimization and mechanistic studies of psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA). Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 4296-310. PMID 11686610 DOI: 10.1002/1521-3765(20011001)7:19<4296::Aid-Chem4296>3.0.Co;2-2 |
0.745 |
|
| 2001 |
Nicolaou KC, Hughes R, Pfefferkorn JA, Barluenga S, Roecker AJ. Combinatorial synthesis through disulfide exchange: discovery of potent psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA). Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 4280-95. PMID 11686609 DOI: 10.1002/1521-3765(20011001)7:19<4280::Aid-Chem4280>3.0.Co;2-3 |
0.782 |
|
| 2000 |
Nicolaou KC, Murphy F, Barluenga S, Ohshima T, Wei H, Xu J, Gray DLF, Baudoin O. Total Synthesis of the Novel Immunosuppressant Sanglifehrin A Journal of the American Chemical Society. 122: 3830-3838. DOI: 10.1021/Ja994285V |
0.67 |
|
| 2000 |
Nicolaou KC, Pfefferkorn JA, Barluenga S, Mitchell HJ, Roecker AJ, Cao GQ. Natural product-like combinatorial libraries based on privileged structures. 3. The 'libraries from libraries' principle for diversity enhancement of benzopyran libraries Journal of the American Chemical Society. 122: 9968-9976. DOI: 10.1021/Ja0020355 |
0.787 |
|
| 2000 |
Nicolaou KC, Pfefferkorn JA, Mitchell HJ, Roecker AJ, Barluenga S, Cao GQ, Affleck RL, Lillig JE. Natural product-like combinatorial libraries based on privileged structures. 2. Construction of a 10 000-membered benzopyran library by directed split-and-pool chemistry using NanoKans and optical encoding Journal of the American Chemical Society. 122: 9954-9967. DOI: 10.1021/Ja002034C |
0.799 |
|
| 1999 |
Nicolaou KC, Xu J, Murphy F, Barluenga S, Baudoin O, Wei Hx, Gray DL, Ohshima T. Total Synthesis of Sanglifehrin A. Angewandte Chemie (International Ed. in English). 38: 2447-2451. PMID 10458817 DOI: 10.1002/(Sici)1521-3773(19990816)38:16<2447::Aid-Anie2447>3.0.Co;2-O |
0.725 |
|
| 1999 |
Barluenga J, Aznar F, Palomero MA, Barluenga S. Unexpected Thermal Benzannulation of 1,3,5-Metallahexatrienes: Synthesis ofo-Alkoxyphenol-Containing Polycycles Organic Letters. 1: 541-544. DOI: 10.1021/Ol9906256 |
0.452 |
|
| 1999 |
Nicolaou K, Xu J, Murphy F, Barluenga S, Baudoin O, Wei H, Gray D, Ohshima T. Totalsynthese von Sanglifehrin A Angewandte Chemie. 111: 2599-2604. DOI: 10.1002/(Sici)1521-3757(19990816)111:16<2599::Aid-Ange2599>3.0.Co;2-7 |
0.657 |
|
| 1999 |
Nicolaou KC, Ohshima T, Murphy F, Barluenga S, Xu J, Winssinger N. Synthesis of the macrocyclic core of sanglifehrin A Chemical Communications. 809-810. |
0.654 |
|
| 1998 |
Barluenga J, Aznar F, Barluenga S, Martín A, García-Granda S, Martín E. Tandem Cycloaddition-Cyclopentannulation Processes of 2-Aminobuta-1,3-dienes and Fischer Alkynylcarbene Complexes as a Tool for the Preparation of Complex Polycyclic Scaffolds Synlett. 1998: 473-474. DOI: 10.1055/S-1998-1704 |
0.41 |
|
| 1998 |
Nicolaou KC, Pastor J, Barluenga S, Winssinger NC. Polymer-supported selenium reagents for organic synthesis Chemical Communications. 1947-1948. DOI: 10.1039/A804795B |
0.433 |
|
| 1998 |
Barluenga J, Aznar F, Barluenga S, Fernández M, Martín A, García-Granda S, Piñera-Nicolás A. Reactions of 2-Amino-1,3-butadienes and Fischer Alkynyl Carbenes: Up to Nine C−C Bonds and Seven Stereogenic Centers Created in a Stereoselective Manner through a Cascade Process Chemistry - a European Journal. 4: 2280-2298. DOI: 10.1002/(Sici)1521-3765(19981102)4:11<2280::Aid-Chem2280>3.0.Co;2-# |
0.437 |
|
| 1998 |
Nicolaou KC, Pastor J, Barluenga S, Winssinger N. Polymer-supported selenium reagents for organic synthesis Chemical Communications. 1947-1948. |
0.62 |
|
| 1997 |
Barluenga J, Aznar F, Barluenga S, García-Granda S, Alvarez-Rúa C. Stereospecific [4+2] Reaction between 2-Morpholino-1,3-butadienes and α,β-Unsaturated Exocyclic Chromium Carbene Complexes. Preparation of Enantiomerically Pure Spiro Compounds Synlett. 1997: 1040-1042. DOI: 10.1055/S-1997-1539 |
0.427 |
|
| 1997 |
Barluenga J, Aznar F, Martín A, Barluenga S. Enantioselective synthesis of six membered carbocycles through [4+2] cycloaddition reactions of chiral 2-amino-1,3-butadienes and tungsten vinyl Fischer type carbene complexes Tetrahedron. 53: 9323-9340. DOI: 10.1016/S0040-4020(97)00586-3 |
0.473 |
|
| 1995 |
Barluenga J, Aznar F, Barluenga S. Unexpected and easy annulation of Fischer-type phenylethenyl carbene complexes Journal of the Chemical Society, Chemical Communications. 1973-1974. DOI: 10.1039/C39950001973 |
0.436 |
|
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