Year |
Citation |
Score |
2023 |
Benin BM, Hillyer T, Crugnale AS, Fulk A, Thomas CA, Crowder MW, Smith MA, Shin WS. Taxifolin as a Metallo-β-Lactamase Inhibitor in Combination with Augmentin against Verona Imipenemase 2 Expressing . Microorganisms. 11. PMID 38004664 DOI: 10.3390/microorganisms11112653 |
0.775 |
|
2023 |
Thoden JB, Benin BM, Priebe A, Shin WS, Muthyala R, Sham YY, Holden HM. Characterization of a novel inhibitor for the New Delhi metallo-β-lactamase-4: implications for drug design and combating bacterial drug resistance. The Journal of Biological Chemistry. 105135. PMID 37549809 DOI: 10.1016/j.jbc.2023.105135 |
0.764 |
|
2023 |
Hillyer T, Benin BM, Sun C, Aguirre N, Willard B, Sham YY, Shin WS. A novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii. Scientific Reports. 13: 9177. PMID 37280269 DOI: 10.1038/s41598-023-36475-9 |
0.759 |
|
2023 |
Abeydeera N, Benin BM, Mudarmah K, Pant BD, Chen G, Shin WS, Kim MH, Huang SD. Harnessing the Dual Antimicrobial Mechanism of Action with Fe(8-Hydroxyquinoline) to Develop a Topical Ointment for Mupirocin-Resistant MRSA Infections. Antibiotics (Basel, Switzerland). 12. PMID 37237789 DOI: 10.3390/antibiotics12050886 |
0.687 |
|
2023 |
Sun C, Zhou K, DePaola P, Shin W, Hillyer T, Sawaya M, Zhu R, Peng C, Zhou ZH, Jiang L. Cryo-EM structure of amyloid fibril formed by α-synuclein hereditary A53E mutation reveals a distinct protofilament interface. The Journal of Biological Chemistry. 104566. PMID 36871760 DOI: 10.1016/j.jbc.2023.104566 |
0.343 |
|
2023 |
Hillyer T, Benin BM, Sun C, Aguirre N, Willard B, Sham YY, Shin WS. A novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii. Research Square. PMID 36711967 DOI: 10.21203/rs.3.rs-2359505/v1 |
0.759 |
|
2021 |
Shin WS, Nguyen ME, Bergstrom A, Jennings IR, Crowder MW, Muthyala R, Sham YY. Fragment based screening and hit-based substructure search: Rapid discovery of 8-hydroxyquinoline-7-carboxylic acid as a low-cytotoxic, nanomolar metallo β-lactamase inhibitor. Chemical Biology & Drug Design. PMID 34148302 DOI: 10.1111/cbdd.13912 |
0.768 |
|
2021 |
Shin WS, Di J, Cao Q, Li B, Seidler PM, Murray KA, Bitan G, Jiang L. Correction to: Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation. Alzheimer's Research & Therapy. 13: 83. PMID 33879220 DOI: 10.1186/s13195-021-00824-5 |
0.413 |
|
2019 |
Shin WS, Di J, Murray KA, Sun C, Li B, Bitan G, Jiang L. Different Amyloid-β Self-Assemblies Have Distinct Effects on Intracellular Tau Aggregation. Frontiers in Molecular Neuroscience. 12: 268. PMID 31787880 DOI: 10.3389/Fnmol.2019.00268 |
0.326 |
|
2019 |
Shin WS, Di J, Cao Q, Li B, Seidler PM, Murray KA, Bitan G, Jiang L. Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation. Alzheimer's Research & Therapy. 11: 86. PMID 31627745 DOI: 10.1186/S13195-019-0541-9 |
0.392 |
|
2019 |
Gui X, Luo F, Li Y, Zhou H, Qin Z, Liu Z, Gu J, Xie M, Zhao K, Dai B, Shin WS, He J, He L, Jiang L, Zhao M, et al. Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly. Nature Communications. 10: 2006. PMID 31043593 DOI: 10.1038/S41467-019-09902-7 |
0.303 |
|
2018 |
Cao Q, Shin WS, Chan H, Vuong CK, Dubois B, Li B, Murray KA, Sawaya MR, Feigon J, Black DL, Eisenberg DS, Jiang L. Author Correction: Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design. Nature Chemistry. PMID 30420778 DOI: 10.1038/S41557-018-0182-9 |
0.397 |
|
2018 |
Cao Q, Shin WS, Chan H, Vuong CK, Dubois B, Li B, Murray KA, Sawaya MR, Feigon J, Black DL, Eisenberg DS, Jiang L. Inhibiting amyloid-ß cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design. Nature Chemistry. PMID 30297750 DOI: 10.1038/S41557-018-0147-Z |
0.368 |
|
2018 |
Li B, Ge P, Murray KA, Sheth P, Zhang M, Nair G, Sawaya MR, Shin WS, Boyer DR, Ye S, Eisenberg DS, Zhou ZH, Jiang L. Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel. Nature Communications. 9: 3609. PMID 30190461 DOI: 10.1038/s41467-018-05971-2 |
0.351 |
|
2017 |
Muthyala R, Shin WS, Sham YY, Bergstrom A, Crowder MW, Bonomo RA. Discovery of 1-hydroxypyridine-2(1H)-thione-6-carboxylic acid as a first-in-class low-cytotoxic nanomolar metallo -lactamase inhibitor. Chemmedchem. PMID 28482143 DOI: 10.1002/Cmdc.201700182 |
0.651 |
|
2015 |
Muthyala R, Shin WS, Xie J, Sham YY. Discovery of 1-hydroxypyridine-2-thiones as selective histone deacetylase inhibitors and their potential application for treating leukemia. Bioorganic & Medicinal Chemistry Letters. 25: 4320-4. PMID 26264503 DOI: 10.1016/J.Bmcl.2015.07.065 |
0.585 |
|
2014 |
Zhuang C, Sheng C, Shin WS, Wu Y, Li J, Yao J, Dong G, Zhang W, Sham YY, Miao Z, Zhang W. A novel drug discovery strategy: mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-κB pathways. Oncotarget. 5: 10830-9. PMID 25350970 DOI: 10.18632/Oncotarget.2521 |
0.561 |
|
2014 |
Muthyala R, Rastogi N, Shin WS, Peterson ML, Sham YY. Cell permeable vanX inhibitors as vancomycin re-sensitizing agents Bioorganic and Medicinal Chemistry Letters. 24: 2535-2538. PMID 24751446 DOI: 10.1016/J.Bmcl.2014.03.097 |
0.622 |
|
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