| Year |
Citation |
Score |
| 2020 |
Borthwick JA, Alemparte C, Wall I, Whitehurst BC, Argyrou A, Burley GA, de Dios-Anton P, Guijarro L, Monteiro MC, Ortega F, Suckling CJ, Castro-Pichel J, Cacho M, Young RJ. Mycobacterium tuberculosis Decaprenylphosphoryl-β-D-ribose Oxidase inhibitors: expeditious reconstruction of sub-optimal hits into a series with potent in vivo activity. Journal of Medicinal Chemistry. PMID 31922409 DOI: 10.1021/Acs.Jmedchem.9B01561 |
0.309 |
|
| 2018 |
Procopiou PA, Anderson NA, Barrett J, Barrett TN, Crawford MHJ, Fallon BJ, Hancock AP, Le J, Lemma S, Marshall RP, Morrell J, Pritchard JM, Rowedder JE, Saklatvala P, Slack RJ, ... ... Suckling CJ, et al. Discovery of ( S)-3-(3-(3,5-Dimethyl-1 H-pyrazol-1-yl)phenyl)-4-(( R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic αβ Integrin Inhibitor for the Inhaled Treatment of Idiopathic Pulmonary Fibrosis. Journal of Medicinal Chemistry. PMID 30215258 DOI: 10.1021/Acs.Jmedchem.8B00959 |
0.344 |
|
| 2017 |
Scott FJ, Nichol RJO, Khalaf AI, Giordani F, Gillingwater K, Ramu S, Elliott A, Zuegg J, Duffy P, Rosslee MJ, Hlaka L, Kumar S, Ozturk M, Brombacher F, Barrett M, ... ... Suckling CJ, et al. An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics. European Journal of Medicinal Chemistry. 136: 561-572. PMID 28544982 DOI: 10.1016/J.Ejmech.2017.05.039 |
0.315 |
|
| 2017 |
Kennedy AR, Khalaf AI, Scott FJ, Suckling CJ. Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders. Acta Crystallographica. Section E, Crystallographic Communications. 73: 254-259. PMID 28217354 DOI: 10.1107/S2056989017001177 |
0.349 |
|
| 2016 |
Scott FJ, Khalaf AI, Giordani F, Wong PE, Duffy S, Barrett M, Avery VM, Suckling CJ. An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics. European Journal of Medicinal Chemistry. 116: 116-125. PMID 27060763 DOI: 10.1016/J.Ejmech.2016.03.064 |
0.326 |
|
| 2016 |
Westaway SM, Preston AG, Barker MD, Brown F, Brown JA, Campbell M, Chung CW, Drewes G, Eagle R, Garton N, Gordon L, Haslam C, Hayhow TG, Humphreys PG, Joberty G, ... ... Suckling CJ, et al. Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives. Journal of Medicinal Chemistry. PMID 26771203 DOI: 10.1021/Acs.Jmedchem.5B01538 |
0.303 |
|
| 2015 |
Bertrand SM, Ancellin N, Beaufils B, Bingham RP, Borthwick JA, Boullay AB, Boursier E, Carter PS, Chung CW, Churcher I, Dodic N, Fouchet MH, Fournier C, Francis PL, Gummer LA, ... ... Suckling CJ, et al. The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits. Journal of Medicinal Chemistry. PMID 26090771 DOI: 10.1021/Acs.Jmedchem.5B00313 |
0.312 |
|
| 2014 |
Lünse CE, Scott FJ, Suckling CJ, Mayer G. Novel TPP-riboswitch activators bypass metabolic enzyme dependency. Frontiers in Chemistry. 2: 53. PMID 25121086 DOI: 10.3389/Fchem.2014.00053 |
0.333 |
|
| 2014 |
Khalaf AI, Huggan JK, Suckling CJ, Gibson CL, Stewart K, Giordani F, Barrett MP, Wong PE, Barrack KL, Hunter WN. Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1. Journal of Medicinal Chemistry. 57: 6479-94. PMID 25007262 DOI: 10.1021/Jm500483B |
0.34 |
|
| 2014 |
Lang S, Khalaf AI, Breen D, Huggan JK, Clements CJ, MacKay SP, Suckling CJ. Oligoamides of 2-amino-5-alkylthiazole 4-carboxylic acids: Anti-trypanosomal compounds Medicinal Chemistry Research. 23: 1170-1179. DOI: 10.1007/S00044-013-0723-0 |
0.357 |
|
| 2013 |
Barrett MP, Gemmell CG, Suckling CJ. Minor groove binders as anti-infective agents. Pharmacology & Therapeutics. 139: 12-23. PMID 23507040 DOI: 10.1016/J.Pharmthera.2013.03.002 |
0.353 |
|
| 2013 |
Suckling CJ. The diversity-oriented synthesis of pteridines - achievements and potential for development. Iubmb Life. 65: 283-99. PMID 23440881 DOI: 10.1002/Iub.1148 |
0.343 |
|
| 2013 |
Bochatay VN, Boissarie PJ, Murphy JA, Suckling CJ, Lang S. Mechanistic exploration of the palladium-catalyzed process for the synthesis of benzoxazoles and benzothiazoles. The Journal of Organic Chemistry. 78: 1471-7. PMID 23316812 DOI: 10.1021/Jo302544D |
0.314 |
|
| 2012 |
Khalaf AI, Bourdin C, Breen D, Donoghue G, Scott FJ, Suckling CJ, Macmillan D, Clements C, Fox K, Sekibo DA. Design, synthesis and antibacterial activity of minor groove binders: the role of non-cationic tail groups. European Journal of Medicinal Chemistry. 56: 39-47. PMID 22948178 DOI: 10.1016/J.Ejmech.2012.08.013 |
0.317 |
|
| 2012 |
Suckling C. From multiply active natural product to candidate drug? Antibacterial (and other) minor groove binders for DNA Future Medicinal Chemistry. 4: 971-989. PMID 22650239 DOI: 10.4155/Fmc.12.52 |
0.333 |
|
| 2012 |
Anderson NA, Fallon BJ, Valverde E, MacDonald SJF, Pritchard JM, Suckling CJ, Watson AJB. Asymmetric rhodium-catalysed addition of arylboronic acids to acyclic unsaturated esters containing a basic γ-amino group Synlett. 23: 2817-2821. DOI: 10.1055/S-0032-1317512 |
0.331 |
|
| 2011 |
Baiget J, Llona-Minguez S, Lang S, Mackay SP, Suckling CJ, Sutcliffe OB. Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine. Beilstein Journal of Organic Chemistry. 7: 1407-11. PMID 22043251 DOI: 10.3762/Bjoc.7.164 |
0.355 |
|
| 2011 |
Khalaf AI, Anthony N, Breen D, Donoghue G, Mackay SP, Scott FJ, Suckling CJ. Amide isosteres in structure-activity studies of antibacterial minor groove binders. European Journal of Medicinal Chemistry. 46: 5343-55. PMID 21908079 DOI: 10.1016/J.Ejmech.2011.08.035 |
0.359 |
|
| 2011 |
Adcock J, Gibson CL, Huggan JK, Suckling CJ. Diversity oriented synthesis: substitution at C5 in unreactive pyrimidines by Claisen rearrangement and reactivity in nucleophilic substitution at C2 and C4 in pteridines and pyrido[2,3-d]pyrimidines Tetrahedron. 67: 3226-3237. DOI: 10.1016/J.Tet.2011.03.011 |
0.348 |
|
| 2010 |
Tulloch LB, Martini VP, Iulek J, Huggan JK, Lee JH, Gibson CL, Smith TK, Suckling CJ, Hunter WN. Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases. Journal of Medicinal Chemistry. 53: 221-9. PMID 19916554 DOI: 10.1021/Jm901059X |
0.326 |
|
| 2009 |
Kennedy AR, Khalaf AI, Suckling CJ. 2,2,2-Trifluoro-N-(isoquinolin-5-ylmeth-yl)acetamide. Acta Crystallographica. Section E, Structure Reports Online. 66: o135. PMID 21580026 DOI: 10.1107/S1600536809052994 |
0.301 |
|
| 2009 |
Anthony NG, Breen D, Donoghue G, Khalaf AI, Mackay SP, Parkinson JA, Suckling CJ. A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity. Organic & Biomolecular Chemistry. 7: 1843-50. PMID 19590779 DOI: 10.1039/B901898K |
0.331 |
|
| 2009 |
Gibson CL, Huggan JK, Kennedy A, Kiefer L, Lee JH, Suckling CJ, Clements C, Harvey AL, Hunter WN, Tulloch LB. Diversity oriented syntheses of fused pyrimidines designed as potential antifolates. Organic & Biomolecular Chemistry. 7: 1829-42. PMID 19590778 DOI: 10.1039/B818339B |
0.391 |
|
| 2009 |
Breen D, Kennedy AR, Suckling CJ. A divergent synthesis of minor groove binders with tail group variation Organic and Biomolecular Chemistry. 7: 178-186. PMID 19081961 DOI: 10.1039/B814452D |
0.351 |
|
| 2008 |
Suckling CJ, Gibson CL, Huggan JK, Morthala RR, Clarke B, Kununthur S, Wadsworth RM, Daff S, Papale D. 6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases. Bioorganic & Medicinal Chemistry Letters. 18: 1563-6. PMID 18261902 DOI: 10.1016/J.Bmcl.2008.01.079 |
0.302 |
|
| 2008 |
Gibson CL, Kennedy AR, Morthala RR, Parkinson JA, Suckling CJ. Tetramic acid and imidazolidinone syntheses via unexpected base induced cyclisations of alanine derived Weinreb amides Tetrahedron. 64: 7619-7625. DOI: 10.1016/J.Tet.2008.05.058 |
0.352 |
|
| 2008 |
Suckling CJ. Molecular recognition and physicochemical properties in the discovery of selective antibacterial minor groove binders Journal of Physical Organic Chemistry. 21: 575-583. DOI: 10.1002/Poc.1323 |
0.366 |
|
| 2007 |
Anthony NG, Breen D, Clarke J, Donoghue G, Drummond AJ, Ellis EM, Gemmell CG, Helesbeux JJ, Hunter IS, Khalaf AI, Mackay SP, Parkinson JA, Suckling CJ, Waigh RD. Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. Journal of Medicinal Chemistry. 50: 6116-25. PMID 17960927 DOI: 10.1021/Jm070831G |
0.319 |
|
| 2006 |
Kennedy AR, Khalaf AI, Suckling CJ, Waigh RD. 3-Nitro-1-(triisopropylsilyl)-1H-pyrrole Acta Crystallographica Section E-Structure Reports Online. 62. DOI: 10.1107/S1600536806025943 |
0.328 |
|
| 2006 |
Gibson CL, Huggan JK, Kennedy AR, Suckling CJ. Ethyl 2-({6-amino-2-(benzylsulfanyl)-5-[2-(ethoxycarbonyl)prop-2-enyl]pyrimidin-4-yloxy}methyl)acrylate Acta Crystallographica Section E-Structure Reports Online. 62. DOI: 10.1107/S1600536805041899 |
0.343 |
|
| 2004 |
Khalaf AI, Ebrahimabadi AH, Drummond AJ, Anthony NG, Mackay SP, Suckling CJ, Waigh RD. Synthesis and antimicrobial activity of some netropsin analogues Organic and Biomolecular Chemistry. 2: 3119-3127. PMID 15505717 DOI: 10.1039/B408386P |
0.338 |
|
| 2004 |
Khalaf AI, Waigh RD, Drummond AJ, Pringle B, McGroarty I, Skellern GG, Suckling CJ. Distamycin Analogues with Enhanced Lipophilicity: Synthesis and Antimicrobial Activity Journal of Medicinal Chemistry. 47: 2133-2156. PMID 15056010 DOI: 10.1021/Jm031089X |
0.385 |
|
| 2004 |
Suckling CJ. Minor groove binders 1998 – 2004 Expert Opinion On Therapeutic Patents. 14: 1693-1724. DOI: 10.1517/13543776.14.12.1693 |
0.337 |
|
| 2004 |
Gibson CL, Rosa SL, Ohta K, Boyle PH, Leurquin F, Lemaçon A, Suckling CJ. The synthesis of 7-deazaguanines as potential inhibitors of guanosine triphosphate cyclohydrolase I Tetrahedron. 60: 943-959. DOI: 10.1016/J.Tet.2003.11.030 |
0.385 |
|
| 2003 |
Gibson CL, La Rosa S, Suckling CJ. A prototype solid phase synthesis of pteridines and related heterocyclic compounds. Organic & Biomolecular Chemistry. 1: 1909-18. PMID 12945773 DOI: 10.1039/B300798G |
0.349 |
|
| 2003 |
Guiney D, Gibson CL, Suckling CJ. Syntheses of highly functionalised 6-substituted pteridines. Organic & Biomolecular Chemistry. 1: 664-75. PMID 12929453 DOI: 10.1039/B211564F |
0.391 |
|
| 2003 |
Kennedy AR, Khalaf AI, Suckling CJ, Waigh RD. Ethyl 5-oxo-2,5-dihydro-4-isoxazolecarboxylate hydroxylamine salt Acta Crystallographica Section E-Structure Reports Online. 59: 1410-1412. DOI: 10.1107/S1600536803018828 |
0.318 |
|
| 2001 |
Alvarez RG, Hunter IS, Suckling CJ, Thomas M, Vitinius U. A novel biotransformation of benzofurans and related compounds catalysed by a chloroperoxidase Tetrahedron. 57: 8581-8587. DOI: 10.1016/S0040-4020(01)00837-7 |
0.374 |
|
| 2000 |
Fishleigh RV, Fox KR, Khalaf AI, Pitt AR, Scobie M, Suckling CJ, Urwin J, Waigh RD, Young SC. DNA binding, solubility, and partitioning characteristics of extended lexitropsins. Journal of Medicinal Chemistry. 43: 3257-3266. PMID 10966744 DOI: 10.1021/Jm990620E |
0.311 |
|
| 2000 |
Khalaf AI, Pitt AR, Scobie M, Suckling CJ, Urwin J, Waigh RD, Fishleigh RV, Young SC. Synthesis of novel DNA binding agents: indole-containing analogs of bis-netropsin Journal of Chemical Research-S. 2000: 264-265. DOI: 10.3184/030823400103167444 |
0.328 |
|
| 2000 |
Khalaf AI, Linaza S, Pitt AR, Stimson WH, Suckling CJ. On the Specificity of Reactions Catalysed by the Antibody H11 Tetrahedron. 56: 489-495. DOI: 10.1016/S0040-4020(99)01037-6 |
0.313 |
|
| 2000 |
Khalaf AI, Alvarez RG, Suckling CJ, Waigh RD. Unexpected Dealkylation During Nucleophilic Substitution: Synthesis of 2-N,N-Dialkylamino Benzoxazoles and Benzothiazoles Tetrahedron. 56: 8567-8571. DOI: 10.1016/S0040-4020(00)00802-4 |
0.331 |
|
| 2000 |
Khalaf AI, Pitt AR, Scobie M, Suckling CJ, Urwin J, Waigh RD, Fishleigh RV, Young SC, Wylie WA. The Synthesis of Some Head to Head Linked DNA Minor Groove Binders Tetrahedron. 56: 5225-5239. DOI: 10.1016/S0040-4020(00)00432-4 |
0.341 |
|
| 1999 |
Kennedy A, Khalaf AI, Pitt AP, Scobie M, Suckling CJ, Urwin J, Waigh RD, Young SC. Methyl 2-amino-4-(methoxymethyl)thiazole-5-carboxylate Acta Crystallographica Section C-Crystal Structure Communications. 55. DOI: 10.1107/S0108270199099199 |
0.32 |
|
| 1999 |
Thomas MG, Suckling CJ, Pitt AR, Suckling KE. The synthesis of A- and B-ring fluorinated analogues of cholesterol Journal of the Chemical Society-Perkin Transactions 1. 3191-3198. DOI: 10.1039/A904826J |
0.321 |
|
| 1999 |
Gibson CL, Lang A, Ohta K, Suckling CJ. Specific inhibitors in vitamin biosynthesis. Part 11. Syntheses of pterins with extended side chains at C-6 Journal of the Chemical Society-Perkin Transactions 1. 163-170. DOI: 10.1039/A807756H |
0.357 |
|
| 1998 |
Gibson CL, Ohta K, Paulini K, Suckling CJ. Specific inhibitors in vitamin biosynthesis. Part 10. Synthesis of 7- and 8-substituted 7-deazaguanines Journal of the Chemical Society-Perkin Transactions 1. 3025-3032. DOI: 10.1039/A804037K |
0.376 |
|
| 1997 |
Gibson CL, Paulini K, Suckling CJ. Synthesis of potential inhibitors of GTP-cyclohydrolase I: anefficient synthesis of 8-substituted 7-deazaguanines Chemical Communications. 371-372. DOI: 10.1039/A608297A |
0.335 |
|
| 1997 |
Dufton MJ, Gibson CL, Pitt AR, Athmani S, Suckling CJ. On the mechanism of action of GTP-transforming enzymes Bioorganic & Medicinal Chemistry Letters. 7: 779-784. DOI: 10.1016/S0960-894X(97)00093-0 |
0.313 |
|
| 1996 |
Dunn C, Gibson CL, Suckling CJ. The synthesis of fluorine-containing pterins Tetrahedron. 52: 13017-13026. DOI: 10.1016/0040-4020(96)00782-X |
0.319 |
|
| 1996 |
Pitt AR, Stimson WH, Suckling CJ, Marrero-Tellado JJ, Vazzana C. Catalytic Properties of the Antibody H11 Israel Journal of Chemistry. 36: 171-175. DOI: 10.1002/Ijch.199600023 |
0.326 |
|
| 1995 |
Currie M, Suckling CJ, Zhu L, Irvine J, Stimson WH. The Synthesis of Haptens and Properties of Catalytic Antibodies Designed to Catalyse Carbanionic Cyclisation Reactions Tetrahedron. 51: 8915-8922. DOI: 10.1016/0040-4020(95)00500-8 |
0.302 |
|
| 1995 |
Husbands S, Fraser W, Suckling CJ, Wood HCS. Latent inhibitors part 11. The synthesis of 5-spirocyclopropyl dihydroorotic acid Tetrahedron. 51: 865-870. DOI: 10.1016/0040-4020(94)00977-3 |
0.393 |
|
| 1994 |
Anderson L, Suckling CJ, Zhu L. An unusual stable adduct in the reaction of pyruvate with papain Chemically modiied by 3-acetyl pyridinium and quinolinium derivatives Bioorganic & Medicinal Chemistry Letters. 4: 1415-1418. DOI: 10.1016/S0960-894X(01)80504-7 |
0.36 |
|
| 1994 |
Husbands S, Suckling CA, Suckling CJ. Latent inhibitors Part 10. The inhibition of carboxypeptidase a by tetrapeptide analogues based on 1-aminocyclopropane carboxylic acid Tetrahedron. 50: 9729-9742. DOI: 10.1016/S0040-4020(01)85539-3 |
0.323 |
|
| 1993 |
Dunn C, Gibson CL, Suckling CJ, Xing W. The Synthesis of Fluorine-Containing Pterins Advances in Experimental Medicine and Biology. 338: 25-28. PMID 8304119 DOI: 10.1007/978-1-4615-2960-6_4 |
0.394 |
|
| 1993 |
Boumrah D, Suckling CJ, Dufton MJ. Characteristics of the peptidase activity contained in Taiwan cobra (Naja naja atra) venom Toxicon. 31: 1293-1303. PMID 8303723 DOI: 10.1016/0041-0101(93)90402-5 |
0.309 |
|
| 1993 |
Kemp A, Ner SK, Rees L, Suckling CJ, Tedford MC, Bell AR, Wrigglesworth R. Latent inhibitors. Part 9. Substrate activated time-dependent inhibition of carboxypeptidase A by aminocyclopropanecarboxylic acid derivatives and analogues Journal of the Chemical Society-Perkin Transactions 1. 1993: 741-748. DOI: 10.1039/P29930000741 |
0.343 |
|
| 1993 |
Suckling CJ, Tedford MC, Bence LM, Irvine JI, Stimson WH. An antibody with dual catalytic activity Journal of the Chemical Society-Perkin Transactions 1. 1925-1929. DOI: 10.1039/P19930001925 |
0.312 |
|
| 1993 |
Owens J, Rees L, Suckling CJ, Wood HCS. The preparation of the (6R)- and (6S)-diastereoisomers of 5-formyltetrahydrofolate (leucovorin) Journal of the Chemical Society-Perkin Transactions 1. 871-876. DOI: 10.1039/P19930000871 |
0.311 |
|
| 1993 |
Aitken DJ, Alijah R, Onyiriuka SO, Suckling CJ, Wood HCS, Zhu L. Approaches to chemically modified enzymes as synthetic catalysts Journal of the Chemical Society-Perkin Transactions 1. 597-608. DOI: 10.1039/P19930000597 |
0.584 |
|
| 1992 |
Suckling CJ. Catalytic antibodies--a new window on protein chemistry. Biochemical Society Transactions. 20: 216-220. PMID 1633947 DOI: 10.1042/Bst0200216 |
0.3 |
|
| 1992 |
Khalaf AI, Proctor GR, Suckling CJ, Bence LH, Irvine JI, Stimson WH. Remarkably efficient hydrolysis of a 4-nitrophenyl ester by a catalytic antibody raised to an ammonium hapten Journal of the Chemical Society-Perkin Transactions 1. 1475-1481. DOI: 10.1039/P19920001475 |
0.316 |
|
| 1992 |
McGill J, Rees L, Suckling CJ, Wood HCS. Latent inhibitors. Part 8. Synthesis and evaluation of some mechanism-based inhibitors of dihydrofolate reductase Journal of the Chemical Society-Perkin Transactions 1. 1299-1304. DOI: 10.1039/P19920001299 |
0.347 |
|
| 1991 |
Kemp A, Tedford C, Suckling CJ. Substrate activated time dependent inhibition of carboxypeptidase a by aminocyclopropane carboxylic acid derivatives and analogues Bioorganic & Medicinal Chemistry Letters. 1: 557-562. DOI: 10.1016/S0960-894X(01)80465-0 |
0.349 |
|
| 1990 |
Fraser W, Suckling CJ, Wood HCS. Latent inhibitors. Part 7. Inhibition of dihydro-orotate dehydrogenase by spirocyclopropanobarbiturates Journal of the Chemical Society-Perkin Transactions 1. 3137-3144. DOI: 10.1039/P19900003137 |
0.38 |
|
| 1990 |
Howie C, Suckling CJ, Wood HCS. Latent inhibitors. Part 6. Inhibition of dihydro-orotate dehydrogenase by substituted 5-benzylhydantoins Journal of the Chemical Society-Perkin Transactions 1. 3129-3135. DOI: 10.1039/P19900003129 |
0.387 |
|
| 1989 |
Haddow J, Suckling CJ, Wood HCS. Latent inhibitors. Part 5. Latent inhibition of dihydrofolate reductase by a pteridine-spiro-cyclopropane Journal of the Chemical Society-Perkin Transactions 1. 1297-1304. DOI: 10.1039/P19890001297 |
0.34 |
|
| 1988 |
Buntain IG, Suckling CJ, Wood HCS. Latent inhibitors. Part 4. Irreversible inhibition of dihydro-orotate dehydrogenase by hydantoins derived from amino acids Journal of the Chemical Society-Perkin Transactions 1. 3175-3182. DOI: 10.1039/P19880003175 |
0.374 |
|
| 1988 |
Pervez H, Onyiriuka SO, Rees L, Rooney JR, Suckling CJ. Selective functionalisatlon Tetrahedron. 44: 4555-4568. DOI: 10.1016/S0040-4020(01)86158-5 |
0.358 |
|
| 1987 |
Haddow J, Suckling CJ, Wood HCS. Latent inhibition of dihydrofolate reductase by a spirocyclopropyl pteridine Journal of the Chemical Society, Chemical Communications. 478-480. DOI: 10.1039/C39870000478 |
0.315 |
|
| 1986 |
Suckling CJ. Studies of enzyme inhibition by compounds containing small rings. Biochemical Society Transactions. 14: 402-404. PMID 2940133 DOI: 10.1042/Bst0140402 |
0.348 |
|
| 1986 |
Aitken DJ, Rees L, Suckling CJ, Wood HCS. Novel Reactivity of 2‐(Chloromethoxy)ethyl Acetate. Tetrahedron Letters. 27: 3417-3420. DOI: 10.1016/S0040-4039(00)84811-X |
0.546 |
|
| 1986 |
Breckenridge RJ, Suckling CJ. Enzyme inhibition by electrophilic cyclopropane derivatives Tetrahedron. 42: 5665-5677. DOI: 10.1016/S0040-4020(01)88172-2 |
0.37 |
|
| 1986 |
Laurie D, Lucas E, Nonhebel DC, Suckling CJ, Walton JC. On the mechanism of hydrogen transfer by nicotinamide coenzymes and some dehydrogenases Tetrahedron. 42: 1035-1045. DOI: 10.1016/S0040-4020(01)87508-6 |
0.346 |
|
| 1986 |
Rees L, Valente E, Suckling CJ, Wood HC. Asymmetric reduction of dihydrofolate using dihydrofolate reductase and chiral boron-containing compounds Tetrahedron. 42: 117-136. DOI: 10.1016/S0040-4020(01)87409-3 |
0.702 |
|
| 1985 |
Suckling CJ, Breckenridge RJ, Bansal SS, Williams LC, Watling KJ, Iversen LL. Non-selective inhibition of GABA and 5-HT uptake systems in rat brain by N-n-alkyl hydroxybenzylamine and N-n-alkyl phenylethylamine derivatives Biochemical Pharmacology. 34: 4173-4177. PMID 4062986 DOI: 10.1016/0006-2952(85)90213-8 |
0.708 |
|
| 1985 |
Al-Hassan SS, Cameron R, Nicholson SH, Robinson DH, Suckling CJ, Wood HCS. Specific inhibitors in vitamin biosynthesis. Part 9.1 reactions of 7,7-dialkyl-7,8-dihydropteridines of use in the synthesis of potential inhibitors of tetrahydrofolate biosynthesis Journal of the Chemical Society, Perkin Transactions 1. 2145-2150. DOI: 10.1039/P19850002145 |
0.42 |
|
| 1985 |
Cameron R, Nicholson SH, Robinson DH, Suckling CJ, Wood HCS. Specific inhibitors in vitamin biosynthesis. Part 8. Syntheses of some functionalised 7,7-dialkyl-7,8-dihydropterins Journal of the Chemical Society, Perkin Transactions 1. 2133-2143. DOI: 10.1039/P19850002133 |
0.392 |
|
| 1985 |
Al-Hassan SS, Cameron RJ, Curran AWC, Lyall WJS, Nicholson SH, Robinson DR, Stuart A, Suckling CJ, Stirling I, Wood HCS. Specific inhibitors in vitamin biosynthesis. Part 7.<sup>1</sup> Syntheses of blocked 7,8-dihydropteridines via α-amino ketones Journal of the Chemical Society, Perkin Transactions 1. 1645-1659. DOI: 10.1039/P19850001645 |
0.382 |
|
| 1985 |
Pervez H, Rees L, Suckling CJ. Selective nitration of phenol Journal of the Chemical Society, Chemical Communications. 512-513. DOI: 10.1039/C39850000512 |
0.325 |
|
| 1985 |
Buntain IG, Suckling CJ, Wood HCS. Irreversible inhibition of dihydro-orotate dehydrogenase by hydantoins derived from amino acids Journal of the Chemical Society, Chemical Communications. 242-244. DOI: 10.1039/C39850000242 |
0.329 |
|
| 1984 |
Wrigglesworth R, Inglis WD, Livingstone DB, Suckling CJ, Wood HCS. Specific enzyme inhibitors in vitamin biosynthesis. Part 6. Identification of an affinity chromatography ligand for the purification of riboflavin synthase Journal of the Chemical Society-Perkin Transactions 1. 15: 959-963. DOI: 10.1039/P19840000959 |
0.33 |
|
| 1984 |
Ginger CD, Wrigglesworth R, Inglis WD, Kulick RJ, Suckling CJ, Wood HCS. Specific enzyme inhibitors in vitamin biosynthesis. Part 5. Purification of riboflavin synthase by affinity chromatography using 7-oxolumazines Journal of the Chemical Society-Perkin Transactions 1. 15: 953-958. DOI: 10.1039/P19840000953 |
0.327 |
|
| 1984 |
Robinson D, Sherrington D, Suckling C. Selective functionalisation-7 Tetrahedron. 40: 785-791. DOI: 10.1016/S0040-4020(01)91108-1 |
0.337 |
|
| 1983 |
Onyiriuka SO, Suckling CJ, Wilson AA. Selective functionalisation. Part 6. The chlorination of phenol in micellar solution Journal of the Chemical Society-Perkin Transactions 1. 14: 1103-1107. DOI: 10.1039/P29830001103 |
0.317 |
|
| 1983 |
Maclnnes I, Nonhebel DC, Orszulik ST, Suckling CJ, Wrigglesworth R. Latent inhibitors. Part 3. The inhibition of lactate dehydrogenase and alcohol dehydrogenase by cyclopropane-containing compounds Journal of the Chemical Society-Perkin Transactions 1. 15: 2771-2776. DOI: 10.1039/P19830002771 |
0.345 |
|
| 1982 |
Suckling KE, Smellie CG, Ibrahim IES, Nonhebel DC, Suckling CJ. The oxidation of cyclopropyl benzene by rat liver microsomal cytochrome P-450: an unusual triple oxidation of a substrate Febs Letters. 145: 179-181. PMID 7128821 DOI: 10.1016/0014-5793(82)80162-2 |
0.31 |
|
| 1982 |
Jackson AH, Kenner GW, Smith KM, Suckling CJ. Synthetic approaches to versatile hemoprotein model compounds built from porphyrins and peptides Journal of the Chemical Society, Perkin Transactions 1. 1441-1448. DOI: 10.1039/P19820001441 |
0.434 |
|
| 1982 |
Nonhebel DC, Orszulik ST, Suckling CJ. 2-Cyclopropaneglyoxylic acid: a probe for the mechanism of hydrogen transfer by lactate dehydrogenase and by N-benzyl-1,4-dihydronicotinamide Journal of the Chemical Society, Chemical Communications. 1146-1147. DOI: 10.1039/C39820001146 |
0.337 |
|
| 1982 |
Suckling CJ. Host–guests binding by a simple detergent derivative: ‘tentacle molecules’ Journal of the Chemical Society, Chemical Communications. 661-662. DOI: 10.1039/C39820000661 |
0.327 |
|
| 1982 |
MacInnes I, Nonhebel DC, Orszulik ST, Suckling CJ. Cyclopropylmethyl compounds as probes of the mechanism of hydrogen transfer by NAD(H) and alcohol dehydrogenase Journal of the Chemical Society, Chemical Communications. 121-122. DOI: 10.1039/C39820000121 |
0.315 |
|
| 1981 |
MacInnes I, Schorstein DE, Suckling CJ, Wrigglesworth R. Latent inhibitors. Part 2. Allylic inhibitors of alcohol dehydrogenase Journal of the Chemical Society-Perkin Transactions 1. 1103-1108. DOI: 10.1039/P19810001103 |
0.366 |
|
| 1980 |
Al-Hassan SS, Kulick RJ, Livingstone DB, Suckling CJ, Wood HCS, Wrigglesworth R, Ferone R. Specific enzyme inhibitors in vitamin biosynthesis. Part 3. The synthesis and inhibitory properties of some substrates and transition state analogues of riboflavin synthase Journal of the Chemical Society-Perkin Transactions 1. 12: 2645-2656. DOI: 10.1039/P19800002645 |
0.363 |
|
| 1977 |
Shirra A, Suckling CJ. Pyridinium salts and dihydropyridines; mechanistic studies of the redox reaction between pyridinium salts and alkoxides in tetrahydrofuran Journal of the Chemical Society-Perkin Transactions 1. 8: 759-765. DOI: 10.1039/P29770000759 |
0.313 |
|
| 1977 |
JACKSON AH, KENNER GW, SMITH KM, SUCKLING CJ. ChemInform Abstract: PYRROLES AND RELATED COMPOUNDS. XXXVII. HARDEROPORPHYRIN Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197711341 |
0.313 |
|
| 1976 |
Jackson AH, Kenner GW, Smith KM, Suckling CJ. Pyrroles and related compounds-XXXVII. Harderoporphyrin Tetrahedron. 32: 2757-2762. DOI: 10.1016/0040-4020(76)80119-6 |
0.357 |
|
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